| 1 | A | B | C | D | E | F | G |
| --- | --- | --- | --- | --- | --- | --- | --- |
| 2 | IFFO1 - Orthologs |  |  |  |  |  |  |
| 3 | Genus/Species | Common Name | Divergence from Human (MYA) | Length (aa) | Similarity | Identity | NCBI Accession |
| 4 | Homo sapiens | Human | N/A | 570 | 100% | 100% | XP_006719036.1 |
| 5 | Mus musculus | Mouse | 92.3 | 563 | 93% | 95% | XP_006506337.2 |
| 6 | Lipotes vexillifer | Baiji dolphin | 94.2 | 573 | 92% | 95% | XP_007469487.1 |
| 7 | Loxodonta africana | African bush elephant | 98.7 | 574 | 94% | 96% | XP_003410688.1 |
| 8 | Chrysemys picta bellii | Painted turtle | 296 | 557 | 78% | 84% | XP_005291351.1 |
| 9 | Pseudopodoces humilis | Ground tit | 296 | 531 | 76% | 81% | XP_005523902.1 |
| 10 | Python bivittatus | Burmese python | 296 | 570 | 75% | 82% | XP_007429680.1 |
| 11 | Haliaeetus leucocephalus | Bald eagle | 296 | 537 | 74% | 79% | XP_010565842.1 |
| 12 | Rana catesbeiana | American bull frog | 371.2 | 511 | 25% | 44% | BAB63946.1 |
| 13 | Ambystoma mexicanum | Axolotl | 371.2 | 372 | 24% | 42% | AFN68290.1 |
| 14 | Notophthalmus viridescens | Eastern newt | 371.2 | 496 | 23% | 45% | CAA04656.1 |
| 15 | Danio Rerio | Zebra fish | 400.1 | 640 | 62% | 71% | XP_690165.5 |
| 16 | Poecilia formosa | Amazon molly | 400.1 | 640 | 57% | 65% | XP_007550181.1 |
| 17 | Callorhinchus milii | Australian ghostshark | 462.5 | 512 | 62% | 73% | XP_007896103.1 |

Question: How long ago did the IFFO1 gene in the Australian ghostshark diverge from humans?
Answer: The most distant ortholog was found to be in the Australian ghostshark, IFFO1 gene, which diverged from humans 462.5 million years ago.