| 1 | A | B | C | D | E | F |
| --- | --- | --- | --- | --- | --- | --- |
| 2 | Interleukin-1 family - Nomenclature |  |  |  |  |  |
| 3 | Name | Family name | Receptor | Coreceptor | Property | Chromosomal location |
| 4 | IL-1α | IL-1F1 | IL-1RI | IL-1RAcP | Proinflammatory | 2q14 |
| 5 | IL-1β | IL-1F2 | IL-1RI | IL-1RAcP | Proinflammatory | 2q14 |
| 6 | IL-1Ra | IL-1F3 | IL-1RI | NA | Antagonist for IL-1α, IL-1β | 2q14.2 |
| 7 | IL-18 | IL-1F4 | IL-18Rα | IL-18Rβ | Proinflammatory | 11q22.2-q22.3 |
| 8 | IL-36Ra | IL-1F5 | IL-1Rrp2 | NA | Antagonist for IL-36α, IL-36β, IL-36γ | 2q14 |
| 9 | IL-36α | IL-1F6 | IL-1Rrp2 | IL-1RAcP | Proinflammatory | 2q12 - q14.1 |
| 10 | IL-37 | IL-1F7 | Unknown | Unknown | Anti-inflammatory | 2q12 – q14.1 |
| 11 | IL-36β | IL-1F8 | IL-1Rrp2 | IL-1RAcP | Proinflammatory | 2q14 |
| 12 | IL-36γ | IL1-F9 | IL-1Rrp2 | IL-1RAcP | Proinflammatory | 2q12 – q21 |
| 13 | IL-38 | IL-1F10 | IL-1Rrp2 | Unknown | Anti-inflammatory | 2q13 |
| 14 | IL-33 | IL-1F11 | ST2 | IL-1RAcP | Th2 responses, proinflammatory | 9p24.1 |

Question: For what do IL-1RI and IL-1RAcP serve as receptors and coreceptors?
Answer: IL-1RI and IL-1RAcP serve as receptors and coreceptors for IL-1α and IL-1β.