What are the names of the people who are born to the same mother?
The film opens as a pregnant woman gives birth to a vampire. A young Brother, Silus, aged 10–13 is told this child, Edgar and he are from the same mother. Throughout this introduction, the mother is in visible emotional distress, reaching out across the room to Silus, trying to touch him.
Captioned "100 Years Later." Jamestown slum has had a series of attacks on women, who are all found with their throats bitten. Lilly Squires is in charge of the human police investigating these cases. She states that she comes from a workhouse in this same slum, and we establish that she is one of the few cops who care what happens to these people at the bottom of the socioeconomic heap.  Lilly finds a small boy who witnesses one attack, and tells her that a Brother was responsible. As the police don't want to panic the city, the string of murders is explained away as being the result of an outbreak of the rampant influenza virus.
Silus is detailed by the church cardinals to work with the human police, because the Brothers know that these attacks have been carried out by a Brother; Silus's brother Edgar. Edgar has sent Silus a recording of his last murder, challenging him to find and stop him before he kills again. Edgar provides the location of his next murder.
With Silus' help, Lilly puts together a task force to stake out the area Edgar has targeted. However Edgar distracts the cops and attacks Lilly, biting her in the neck. An officer interrupts the attack and Edgar flees. To save Lilly's life, Silus tells her to drink his blood, which she does. Silus then pursues Edgar, managing to shoot him with a tranquilizing dart. Silus later visits Lilly in hospital. We establish that she has no family as they died from influenza. Lilly is having visions from drinking Silus' blood. The newspapers have published a fake story of the death of the killer; a deranged human who believed he was a Brother.
Silus Edgar