paragraph_text: The research that led to golden rice was conducted with the goal of helping children who suffer from vitamin A deficiency (VAD). In 2005, 190 million children and 19 million pregnant women, in 122 countries, were estimated to be affected by VAD. VAD is responsible for 1–2 million deaths, 500,000 cases of irreversible blindness and millions of cases of xerophthalmia annually. Children and pregnant women are at highest risk. Vitamin A is supplemented orally and by injection in areas where the diet is deficient in vitamin A.

paragraph_text: The Paleozoic spanned from roughly 541 to 252 million years ago (Ma) and is subdivided into six geologic periods; from oldest to youngest they are the Cambrian, Ordovician, Silurian, Devonian, Carboniferous and Permian. Geologically, the Paleozoic starts shortly after the breakup of a supercontinent called Pannotia and at the end of a global ice age. Throughout the early Paleozoic, the Earth's landmass was broken up into a substantial number of relatively small continents. Toward the end of the era the continents gathered together into a supercontinent called Pangaea, which included most of the Earth's land area.

paragraph_text: I, Coriander is a children's novel by Sally Gardner, published in 2005, a historical fantasy set in London at the time of the Puritan Commonwealth. The novel traces the time period of the beheading of Charles the 1st through the Restoration of Charles the 2nd. It won the Nestlé Children's Book Prize Gold Award. It was also shortlisted for the British Children's Book of the Year and the Stockton Children's Book of the Year, as well as longlisted for the Carnegie Medal.

paragraph_text: The Kids of Degrassi Street is a Canadian children's TV series that aired from 1979 to 1986, and is the first series in the "Degrassi" franchise. It follows the lives of a group of children living on Degrassi Street in Toronto, Ontario, Canada. The series grew out of four short films: "Ida Makes a Movie", "Cookie Goes to the Hospital", "Irene Moves In" and "Noel Buys a Suit", which originally aired as after-school specials on CBC Television in 1979, 1980, 1981 and 1982, respectively. The show was acclaimed for its realistic depiction of everyday children's lives and tribulations, and it remains memorable to many Canadians because of this.

paragraph_text: The global temperature record shows the fluctuations of the temperature of the atmosphere and the oceans through various spans of time. The most detailed information exists since 1850, when methodical thermometer - based records began. There are numerous estimates of temperatures since the end of the Pleistocene glaciation, particularly during the current Holocene epoch. Older time periods are studied by paleoclimatology.

paragraph_text: At the time of the Berlin Conference, Africa contained one-fifth of the world’s population living in one-quarter of the world’s land area. However, from Europe's perspective, they were dividing an unknown continent. European countries established a few coastal colonies in Africa by the mid-nineteenth century, which included Cape Colony (Great Britain), Angola (Portugal), and Algeria (France), but until the late nineteenth century Europe largely traded with free African states without feeling the need for territorial possession. Until the 1880s most of Africa remained unchartered, with western maps from the period generally showing blank spaces for the continent’s interior.

paragraph_text: The predominant educational psychology from the 1750s onward, especially in northern European countries was associationism, the notion that the mind associates or dissociates ideas through repeated routines. In addition to being conducive to Enlightenment ideologies of liberty, self-determination and personal responsibility, it offered a practical theory of the mind that allowed teachers to transform longstanding forms of print and manuscript culture into effective graphic tools of learning for the lower and middle orders of society. Children were taught to memorize facts through oral and graphic methods that originated during the Renaissance.

paragraph_text: During the Eocene (56 million years ago - 33.9 million years ago), the continents continued to drift toward their present positions. At the beginning of the period, Australia and Antarctica remained connected, and warm equatorial currents mixed with colder Antarctic waters, distributing the heat around the world and keeping global temperatures high. But when Australia split from the southern continent around 45 Ma, the warm equatorial currents were deflected away from Antarctica, and an isolated cold water channel developed between the two continents. The Antarctic region cooled down, and the ocean surrounding Antarctica began to freeze, sending cold water and ice floes north, reinforcing the cooling. The present pattern of ice ages began about 40 million years ago.[citation needed]

paragraph_text: The symptoms of the disease include a high fever with frontal headaches, followed by haemorrhagic symptoms, such as bleeding from the nasal cavity, throat, and gums, as well as gastrointestinal bleeding.  Other symptoms include vomiting, muscle stiffness, tremors, absent reflexes, and mental disturbances.An affected person may recover in two weeks time, but the convalescent period is typically very long, lasting for several months. There will be muscle aches and weakness during this period and the affected person is unable to engage in physical activities.

paragraph_text: The region also experiences occasional periods of drought, during which the city sometimes has restricted water use by residents. During the late summer and early fall, Raleigh can experience hurricanes. In 1996, Hurricane Fran caused severe damage in the Raleigh area, mostly from falling trees. The most recent hurricane to have a considerable effect on the area was Isabel in 2003. Tornadoes also have on occasion affected the city of Raleigh most notably the November 28, 1988 tornado which occurred in the early morning hours and rated an F4 on the Fujita Tornado Scale and affected Northwestern portions of the city. Also the April 16, 2011 F3 Tornado which affected portions of downtown and North east Raleigh and the suburb of Holly Springs.

paragraph_text: Writing to a friend in May 1795, Burke surveyed the causes of discontent: "I think I can hardly overrate the malignity of the principles of Protestant ascendency, as they affect Ireland; or of Indianism [i.e. corporate tyranny, as practiced by the British East Indies Company], as they affect these countries, and as they affect Asia; or of Jacobinism, as they affect all Europe, and the state of human society itself. The last is the greatest evil". By March 1796, however Burke had changed his mind: "Our Government and our Laws are beset by two different Enemies, which are sapping its foundations, Indianism, and Jacobinism. In some Cases they act separately, in some they act in conjunction: But of this I am sure; that the first is the worst by far, and the hardest to deal with; and for this amongst other reasons, that it weakens discredits, and ruins that force, which ought to be employed with the greatest Credit and Energy against the other; and that it furnishes Jacobinism with its strongest arms against all formal Government".

paragraph_text: There are various methods for determining the clotting time, the most common being the capillary tube method. It is affected by calcium ion levels and many diseases. Normal value of clotting time is 8 to 15 minutes.

paragraph_text: Secondary forestation is common in areas where forests have been lost by the slash-and-burn method, a component of some shifting cultivation systems of agriculture. Secondary forests may also arise from forest that has been harvested heavily or over a long period of time, forest that is naturally regenerating from fire and from abandoned pastures or areas of agriculture.  It takes a secondary forest typically forty to 100 years to begin to resemble the original old-growth forest; however, in some cases a secondary forest will not succeed, due to erosion or soil nutrient loss in certain tropical forests.

paragraph_text: The Ordovician Period started at a major extinction event called the Cambrian-Ordovician extinction events some time about 485.4 ± 1.9 Ma. During the Ordovician the southern continents were collected into a single continent called Gondwana. Gondwana started the period in the equatorial latitudes and, as the period progressed, drifted toward the South Pole. Early in the Ordovician the continents Laurentia, Siberia and Baltica were still independent continents (since the break-up of the supercontinent Pannotia earlier), but Baltica began to move toward Laurentia later in the period, causing the Iapetus Ocean to shrink between them. Also, Avalonia broke free from Gondwana and began to head north toward Laurentia. The Rheic Ocean was formed as a result of this. By the end of the period, Gondwana had neared or approached the pole and was largely glaciated.

paragraph_text: From the 10th to the 13th century, Romanesque architecture had become a pan-European style and manner of construction, affecting buildings in countries as far apart as Ireland, Croatia, Sweden and Sicily. The same wide geographic area was then affected by the development of Gothic architecture, but the acceptance of the Gothic style and methods of construction differed from place to place, as did the expressions of Gothic taste. The proximity of some regions meant that modern country borders do not define divisions of style. On the other hand, some regions such as England and Spain produced defining characteristics rarely seen elsewhere, except where they have been carried by itinerant craftsmen, or the transfer of bishops. Regional differences that are apparent in the great abbey churches and cathedrals of the Romanesque period often become even more apparent in the Gothic.

paragraph_text: The process of polonization took place over a lengthy period of time. At first only the highest members of the nobility were involved, although gradually a wider group of the population was affected. The major effects on the lesser Lithuanian nobility took place after various sanctions were imposed by the Russian Empire such as removing Lithuania from the names of the Gubernyas few years after the November Uprising. After the January Uprising the sanctions went further, and Russian officials announced that "Lithuanians are Russians seduced by Poles and Catholicism" and began to intensify russification, and to ban the printing of books in the Lithuanian language.

paragraph_text: The Renaissance (UK: / rɪˈneɪsəns /, US: / rɛnəˈsɑːns /) is a period in European history, covering the span between the 14th and 17th centuries. It is an extension of the Middle Ages, and is bridged by the Age of Enlightenment to modern history. It grew in fragments, with the very first traces found seemingly in Italy, coming to cover much of Europe, for some scholars marking the beginning of the modern age.

paragraph_text: The approach was originally developed by Harold Garfinkel, who attributed its origin to his work investigating the conduct of jury members in 1954. His interest was in describing the common sense methods through which members of a jury produce themselves in a jury room as a jury. Thus, their methods for: establishing matters of fact; developing evidence chains; determining the reliability of witness testimony; establishing the organization of speakers in the jury room itself; and determining the guilt or innocence of defendants, etc. are all topics of interest. Such methods serve to constitute the social order of being a juror for the members of the jury, as well as for researchers and other interested parties, in that specific social setting.

paragraph_text: An annual venture, the STV Children's Appeal is committed to providing support across a wide range of issues affecting Scotland, and in its first year the charity's work was focused on supporting children and young people affected by poverty.

paragraph_text: Jean-Frédéric Edelmann (Johann Friedrich Edelmann, 5 May 1749 – 17 July 1794) was a French classical composer. He was born in Strasbourg to a Protestant family of Alsatian descent. After studying law and music, he moved to Paris in 1774 where he played and taught the piano. It is possible that Edelmann worked for some time in London. During the French Revolution he was appointed administrator of the Bas-Rhin. In July 1794 he was arrested for being a leader of the local Jacobin faction and executed by guillotine.

Question: In what area did the period of history, in which originated methods to teach children facts, begin on the continent which was affected by Jacobinism?
Answer: seemingly in Italy