paragraph_text: Neural tube defects (NTDs) are a group of birth defects in which an opening in the spinal cord or brain remains from early in human development. In the 3rd week of pregnancy called gastrulation, specialized cells on the dorsal side of the embryo begin to change shape and form the neural tube. When the neural tube does not close completely, an NTD develops.

paragraph_text: Jews in New York City comprise approximately 13 percent of the city's population, making the Jewish community the largest in the world outside of Israel. As of 2014, 1.1 million Jews live in the five boroughs of New York City, and 1.75 million Jews live in New York state overall. Jews have immigrated to New York City since the first settlement in Dutch New Amsterdam in 1654, most notably at the end of the 19th century to the early 20th century, when the Jewish population rose from about 80,000 in 1880 to 1.5 million in 1920. The large Jewish population has led to a significant impact on the culture of New York City. After many decades of decline in the 20th century, the Jewish population of New York City has seen a sharp increase in the 21st century owing to the high birth rate of the Hasidic and Orthodox communities.

paragraph_text: The Honorable Mr. Woodrow Huckleberry Tiberius ``Woody ''Boyd is a character on the American television show Cheers, portrayed by Woody Harrelson. Woody came to Cheers at the beginning of the fourth season of Cheers in 1985 in the episode`` Birth, Death, Love and Rice''.

paragraph_text: Lambing Live is a farming programme which was broadcast live on BBC Two in five parts, beginning on Sunday 7 March 2010. Presented by Kate Humble and Adam Henson, the show was mainly filmed live on the Beavan family farm, near Abergavenny in Monmouthshire and followed a week in the life of the farm, concentrating on the births of the new lambs. Filmed inserts showed the lead-up to the lambing season, including the purchase of two new stud sheep (tups). The show was produced in a style similar to "Springwatch".

paragraph_text: In 2007, about 48 percent of Malians were younger than 12 years old, 49 percent were 15–64 years old, and 3 percent were 65 and older. The median age was 15.9 years. The birth rate in 2014 is 45.53 births per 1,000, and the total fertility rate (in 2012) was 6.4 children per woman. The death rate in 2007 was 16.5 deaths per 1,000. Life expectancy at birth was 53.06 years total (51.43 for males and 54.73 for females). Mali has one of the world's highest rates of infant mortality, with 106 deaths per 1,000 live births in 2007.

paragraph_text: Song of Solomon is a 1977 novel by American author Toni Morrison. It follows the life of Macon ``Milkman ''Dead III, an African - American man living in Michigan, from birth to adulthood.

paragraph_text: Lakeport is a city in Gregg County, Texas, United States. The population was 974 at the 2010 census, up from 861 at the 2000 census.

paragraph_text: As of 2010, the maternal mortality rate was 560 deaths/100,000 live births, and the infant mortality rate was 59.34 deaths/1,000 live births. Female genital mutilation (FGM) is rare in the country, being confined to limited geographic areas of the country.

paragraph_text: Finally, Mowgli stumbles across the village where his adopted human mother (Messua), is now living, which forces him to come to terms with his humanity and decide whether to rejoin his fellow humans in ``The Spring Running ''.

paragraph_text: Fertilization usually occurs in the Fallopian tubes and marks the beginning of embryogenesis. The zygote will then divide over enough generations of cells to form a blastocyst, which implants itself in the wall of the uterus. This begins the period of gestation and the embryo will continue to develop until full - term. When the fetus has developed enough to survive outside the uterus, the cervix dilates and contractions of the uterus propel the newborn through the birth canal (the vagina).

paragraph_text: In classical anatomy, the human stomach is divided into four sections, beginning at the gastric cardia, each of which has different cells and functions.

paragraph_text: The earliest evidence of human habitation in what is now the city of San Francisco dates to 3000 BC. Native Americans who settled in this region found the bay to be a resource for hunting and gathering, leading to the establishment of many small villages. Collectively, these early Native Americans are now known as the Ohlone, and the language they spoke belonged to the Miwok family. Their trade patterns included places as far away as Baja California, the Mojave Desert and Yosemite.

paragraph_text: In the "Epic of Gilgamesh", Ninsun is depicted as a human queen who lives in Uruk with her son as king. Since the father of Gilgamesh was former king Lugalbanda, it stands to reason that Ninsun procreated with Lugalbanda to give birth. She assists her son in his adventure by providing him with the meanings of his dream in the beginning.

paragraph_text: Maternal factors also play a role in the body’s immune response. At birth, most of the immunoglobulin present is maternal IgG. Because IgM, IgD, IgE and IgA don’t cross the placenta, they are almost undetectable at birth. Some IgA is provided by breast milk. These passively-acquired antibodies can protect the newborn for up to 18 months, but their response is usually short-lived and of low affinity. These antibodies can also produce a negative response. If a child is exposed to the antibody for a particular antigen before being exposed to the antigen itself then the child will produce a dampened response. Passively acquired maternal antibodies can suppress the antibody response to active immunization. Similarly the response of T-cells to vaccination differs in children compared to adults, and vaccines that induce Th1 responses in adults do not readily elicit these same responses in neonates. Between six to nine months after birth, a child’s immune system begins to respond more strongly to glycoproteins, but there is usually no marked improvement in their response to polysaccharides until they are at least one year old. This can be the reason for distinct time frames found in vaccination schedules.

paragraph_text: In humans, birth normally occurs at a gestational age of about 40 weeks, though it is common for births to occur from 37 to 42 weeks. After 8 weeks, the embryo is called a fetus.

paragraph_text: Webbed toes is the common name for syndactyly affecting the feet. It is characterised by the fusion of two or more digits of the feet. This is normal in many birds, such as ducks; amphibians, such as frogs; and mammals, such as kangaroos. In humans it is considered unusual, occurring in approximately one in 2,000 to 2,500 live births.

paragraph_text: Matthew Buchanan is a fictional character on the American soap opera "One Life to Live". Born onscreen in 1999, the character was rapidly aged in 2001 with the casting of Eddie Alderson, re-establishing his birth year as 1994 (which is also Alderson's birth year). Alderson stayed with the series until the ABC Daytime finale in 2012. Upon resuming as a web series via The Online Network, Robert Gorrie was cast in the role and debuted April 29, 2013, ultimately revising his birth year to 1992.

paragraph_text: Gregg Tafralis ("Gregory Louis Tafralis;" born April 9, 1958 in San Francisco, California) is a former track and field athlete from the United States, who set the best world year performance in the men's shot put event in 1992. He competed for his native country at the 1988 Summer Olympics, finishing in ninth place.

paragraph_text: Three Bewildered People in the Night is a 1987 American drama film directed by Gregg Araki and starring Darcy Marta, John Lacques, and Mark Howell. The film follows three characters through the dissolution of a heterosexual relationship and the possible beginning of a gay one.

paragraph_text: Emma Watson as Belle, a young benevolent bibliophile woman who develops feelings for the Beast and begins to see the humanity within him. Daisy Duczmal portrays an infant Belle.

Question: When did humans begin to live in Gregg Tafralis's city of birth?
Answer: 3000 BC