paragraph_text: Since its founding in 1949, the People's Republic of China (PRC) has had a diplomatic tug - of - war with its rival in Taiwan, the Republic of China (ROC). Throughout the Cold War, both governments claimed to be the sole legitimate government of all China and allowed countries to recognize either one or the other. Until the 1970s, most Western countries recognized the ROC while the communist bloc and third world countries generally recognized the PRC. This gradually shifted and today only 19 UN member states recognize the ROC while the PRC is recognized by the United Nations and the majority (175) of sovereign states around the world and Palestine. Both the ROC and the PRC maintain the requirement of recognizing its view of the One - China policy to establish or maintain diplomatic relations.

paragraph_text: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extracts were of particular interest to surgeons as hemostatic agents and as treatment for shock, and a number of companies developed products based on adrenal extracts containing varying purities of the active substance. In 1897 John Abel of Johns Hopkins University identified the active principle as epinephrine, which he isolated in an impure state as the sulfate salt. Industrial chemist Jokichi Takamine later developed a method for obtaining epinephrine in a pure state, and licensed the technology to Parke Davis. Parke Davis marketed epinephrine under the trade name Adrenalin. Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). By 1929 epinephrine had been formulated into an inhaler for use in the treatment of nasal congestion.

paragraph_text: The site of the UN headquarters has extraterritoriality status. This affects some law enforcement where UN rules override the laws of New York City, but it does not give immunity to those who commit crimes there. In addition, the United Nations Headquarters remains under the jurisdiction and laws of the United States, although a few members of the UN staff have diplomatic immunity and so can not be prosecuted by local courts unless the diplomatic immunity is waived by the Secretary - General. In 2005, Secretary - General Kofi Annan waived the immunity of Benon Sevan, Aleksandr Yakovlev, and Vladimir Kuznetsov in relation to the Oil - for - Food Programme, and all were charged in the United States District Court for the Southern District of New York. Benon Sevan later fled the United States to Cyprus, while Aleksandr Yakovlev and Vladimir Kuznetsov decided to stand trial.

paragraph_text: Pseudomonas amyloderamosa is a Gram-negative soil bacterium that produces isoamylase. Because this organism is patented, it is not officially recognized as a legitimate "Pseudomonas" species, and therefore has no type strain. It is available, however, through the American Type Culture Collection.

paragraph_text: Serdar Denktaş (in English often spelled "Serdar Denktash") is son of Rauf Denktaş, the former President of the de facto Turkish Republic of Northern Cyprus.

paragraph_text: In 1964, Turkey tried to invade Cyprus in response to the continuing Cypriot intercommunal violence. But Turkey was stopped by a strongly worded telegram from the US President Lyndon B. Johnson on 5 June, warning that the US would not stand beside Turkey in case of a consequential Soviet invasion of Turkish territory. Meanwhile, by 1964, enosis was a Greek policy that could not be abandoned; Makarios and the Greek prime minister Georgios Papandreou agreed that enosis should be the ultimate aim and King Constantine wished Cyprus "a speedy union with the mother country". Greece dispatched 10,000 troops to Cyprus to counter a possible Turkish invasion.

paragraph_text: Organized football was introduced to Cyprus early in the 20th century by the British. Initially played in the island's schools, it proved hugely popular and a number of clubs were duly formed. As football became established, the clubs were united in agreeing that an official body was needed to regulate the sport. On 23 September 1934, the Cyprus Football Association was founded by the following eight clubs: AEL Limassol, Anorthosis Famagusta, APOEL, Aris Limassol, EPA Larnaca, Olympiakos Nicosia, Lefkoşa Türk Spor Kulübü and Trust. After Cyprus Football Association's establishment football began to be played on an official basis with the CFA organizing various championships for its member clubs. It became FIFA member in 1948 and UEFA member in 1962.

paragraph_text: The reaction begins in the amygdala, which triggers a neural response in the hypothalamus. The initial reaction is followed by activation of the pituitary gland and secretion of the hormone ACTH. The adrenal gland is activated almost simultaneously, via the sympathetic nervous system, and releases the hormone epinephrine. The release of chemical messengers results in the production of the hormone cortisol, which increases blood pressure, blood sugar, and suppresses the immune system. The initial response and subsequent reactions are triggered in an effort to create a boost of energy. This boost of energy is activated by epinephrine binding to liver cells and the subsequent production of glucose. Additionally, the circulation of cortisol functions to turn fatty acids into available energy, which prepares muscles throughout the body for response. Catecholamine hormones, such as adrenaline (epinephrine) or noradrenaline (norepinephrine), facilitate immediate physical reactions associated with a preparation for violent muscular action and:

paragraph_text: The Republic of the Congo (French: République du Congo), also known as Congo, Congo Republic, West Congo[citation needed], or Congo-Brazzaville, is a country located in Central Africa. It is bordered by five countries: Gabon to the west; Cameroon to the northwest; the Central African Republic to the northeast; the Democratic Republic of the Congo to the east and south; and the Angolan exclave of Cabinda to the southwest.

paragraph_text: National Pan-Hellenic Council Data Established 1930 Members 9 Continent North America Country United States Headquarters Decatur, Georgia Organization type Coalition of members

paragraph_text: Territories of the United States are sub-national administrative divisions directly overseen by the United States Federal Government. Unlike U.S. states and Native American tribes which exercise limited sovereignty alongside the federal government, territories are without sovereignty. The territories are classified by whether they are incorporated and whether they have an ``organized ''government through an Organic Act passed by the U.S. Congress.

paragraph_text: Cyprus (i/ˈsaɪprəs/; Greek: Κύπρος IPA: [ˈcipros]; Turkish: Kıbrıs IPA: [ˈkɯbɾɯs]), officially the Republic of Cyprus (Greek: Κυπριακή Δημοκρατία; Turkish: Kıbrıs Cumhuriyeti), is an island country in the Eastern Mediterranean Sea, off the coasts of Syria and Turkey.[e] Cyprus is the third largest and third most populous island in the Mediterranean, and a member state of the European Union. It is located south of Turkey, west of Syria and Lebanon, northwest of Israel and Palestine, north of Egypt and east of Greece.

paragraph_text: Canan Öztoprak (born 1955) is a Turkish Republic of Northern Cyprus Cabinet Minister appointed in the April 2005 TRNC Government of Prime Minister Ferdi Sabit Soyer. Her portfolios are National Education and Culture. She has been an active peace activist and founding member of the Cyprus Conflict Resolution Trainers Group.

paragraph_text: Since 1965, following clashes between the two communities, the Turkish Cypriot seats in the House remain vacant. In 1974 Cyprus was divided de facto when the Turkish army occupied the northern third of the island. The Turkish Cypriots subsequently declared independence in 1983 as the Turkish Republic of Northern Cyprus but were recognised only by Turkey. In 1985 the TRNC adopted a constitution and held its first elections. The United Nations recognises the sovereignty of the Republic of Cyprus over the entire island of Cyprus.

paragraph_text: The medication was not readily available globally as of 2015. It was believed that pricing will be similar to bedaquiline, which for six months is approximately US$900 in low income countries, US$3,000 in middle income countries, and US$30,000 in high income countries. As of 2016 the Stop TB Partnership had an agreement to get the medication for US$1,700 per six month.

paragraph_text: This is a list of island countries. An island is a land mass (smaller than a continent) that is surrounded by water. Many island countries are spread over an archipelago, as is the case with the Federated States of Micronesia and the Indonesia (which consists of thousands of islands). Others consist of a single island, such as Nauru, or part of an island, such as Haiti. Although Australia is designated as a continent, it is often referred to as an island, as it has no land borders. Some declared island countries are not universally recognized as politically independent, such as Northern Cyprus. Some states, such as Taiwan, officially claim to hold continental territories but are de facto limited to control over islands.

paragraph_text: The United Nations formulates multiple regional divisions as is convenient for its various operations. But few of them include a Near East, and that poorly defined. UNICEF recognizes the "Middle East and North Africa" region, where the Middle East is bounded by the Red Sea on the west and includes Iran on the east. UNESCO recognizes neither a Near East nor a Middle East, dividing the countries instead among three regions: Arab States, Asia and the Pacific, and Africa. Its division "does not forcibly reflect geography" but "refers to the execution of regional activities." The United Nations Statistics Division defines Western Asia to contain the countries included elsewhere in the Middle East. The Food and Agriculture Organization (FAO) describes its entire theatre of operations as the Near East, but then assigns many of its members to other regions as well; for example, Cyprus, Malta and Turkey are in both the European and the Near Eastern regions. Its total area extends further into Central Asia than that of most agencies.

paragraph_text: The Republic of Cyprus has de jure sovereignty over the island of Cyprus and its surrounding waters, according to international law, except for the British Overseas Territory of Akrotiri and Dhekelia, administered as Sovereign Base Areas. However, the Republic of Cyprus is de facto partitioned into two main parts; the area under the effective control of the Republic, comprising about 59% of the island's area, and the north, administered by the self-declared Turkish Republic of Northern Cyprus, which is recognised only by Turkey, covering about 36% of the island's area. The international community considers the northern part of the island as territory of the Republic of Cyprus occupied by Turkish forces. The occupation is viewed as illegal under international law, amounting to illegal occupation of EU territory since Cyprus became a member of the European Union.

paragraph_text: The North Atlantic Treaty Organization (NATO / ˈneɪtoʊ /; French: Organisation du Traité de l'Atlantique Nord; OTAN), also called the North Atlantic Alliance, is an intergovernmental military alliance between 29 North American and European countries. The organization implements the North Atlantic Treaty that was signed on 4 April 1949. NATO constitutes a system of collective defence whereby its independent member states agree to mutual defence in response to an attack by any external party. NATO's Headquarters are located in Haren, Brussels, Belgium, while the headquarters of Allied Command Operations is near Mons, Belgium.

paragraph_text: ISO 3166-2:CY is the entry for Cyprus in ISO 3166-2, part of the ISO 3166 standard published by the International Organization for Standardization (ISO), which defines codes for the names of the principal subdivisions (e.g., provinces or states) of all countries coded in ISO 3166-1.

Question: When did epinephrine stop being available in the country that contains the headquarters of the organization that recognizes the Republic of Cyprus's sovereignty?
Answer: 2011