paragraph_text: The 2015 Egypt bus accident occurred on 21 March 2015 when a bus fell off a bridge near Giza in Egypt. It plunged into a canal, killing at least 35, many of whom worked for a private construction company.

paragraph_text: Louis van Waefelghem (13 January 1840 in Bruges – 19 June 1908 in Paris) was a Belgian violinist, violist and one of the greatest viola d'amore players of the 19th century. He also composed several works and made transcriptions for viola and viola d'amore.

paragraph_text: Gustav Hollaender (15 February 1855 in Leobschütz – 4 December 1915 in Berlin) was a German violinist, conductor and composer. He composed many violin works including violin concerti. He was uncle of the more famous film composer Friedrich Hollaender.(See "Great Jews in Music" by Darryl Lyman).

paragraph_text: Other forms of plague have been implicated by modern scientists. The modern bubonic plague has a mortality rate of 30–75% and symptoms including fever of 38–41 °C (100–106 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Left untreated, of those that contract the bubonic plague, 80 percent die within eight days. Pneumonic plague has a mortality rate of 90 to 95 percent. Symptoms include fever, cough, and blood-tinged sputum. As the disease progresses, sputum becomes free flowing and bright red. Septicemic plague is the least common of the three forms, with a mortality rate near 100%. Symptoms are high fevers and purple skin patches (purpura due to disseminated intravascular coagulation). In cases of pneumonic and particularly septicemic plague, the progress of the disease is so rapid that there would often be no time for the development of the enlarged lymph nodes that were noted as buboes.

paragraph_text: Medical knowledge had stagnated during the Middle Ages. The most authoritative account at the time came from the medical faculty in Paris in a report to the king of France that blamed the heavens, in the form of a conjunction of three planets in 1345 that caused a "great pestilence in the air". This report became the first and most widely circulated of a series of plague tracts that sought to give advice to sufferers. That the plague was caused by bad air became the most widely accepted theory. Today, this is known as the Miasma theory. The word 'plague' had no special significance at this time, and only the recurrence of outbreaks during the Middle Ages gave it the name that has become the medical term.

paragraph_text: The plague disease, caused by Yersinia pestis, is enzootic (commonly present) in populations of fleas carried by ground rodents, including marmots, in various areas including Central Asia, Kurdistan, Western Asia, Northern India and Uganda. Due to climate change in Asia, rodents began to flee the dried out grasslands to more populated areas, spreading the disease. Nestorian graves dating to 1338 -- 1339 near Lake Issyk Kul in Kyrgyzstan have inscriptions referring to plague and are thought by many epidemiologists to mark the outbreak of the epidemic, from which it could easily have spread to China and India. In October 2010, medical geneticists suggested that all three of the great waves of the plague originated in China. In China, the 13th - century Mongol conquest caused a decline in farming and trading. However, economic recovery had been observed at the beginning of the 14th century. In the 1330s, a large number of natural disasters and plagues led to widespread famine, starting in 1331, with a deadly plague arriving soon after. Epidemics that may have included plague killed an estimated 25 million Chinese and other Asians during the 15 years before it reached Constantinople in 1347.

paragraph_text: Abu al-Fadl Abbas Ibn al-Ahnaf, (750 in Basra-809), Arabic, عباس بن الأحنف, was an Arab Abbasid poet from the clan of Hanifa. His work consists solely of love poems (ghazal). It is "primarily concerned with the hopelessness of love, and the personae in his compositions seems resigned to a relationship of deprivation". The vocabulary he chose was simple and his style is fluent and easy.

paragraph_text: Mezzanotte d'amore (Italian for "Midnight of love") is a 1970 Italian musicarello film directed by Ettore Maria Fizzarotti and starring Al Bano and Romina Power. It is the sequel of "Il suo nome è Donna Rosa".

paragraph_text: Traditional English ale was made solely from fermented malt. The practice of adding hops to produce beer was introduced from the Netherlands in the early 15th century. Alehouses would each brew their own distinctive ale, but independent breweries began to appear in the late 17th century. By the end of the century almost all beer was brewed by commercial breweries.

paragraph_text: Alf Heiberg Clausen (born March 28, 1941) is an American film and television composer. He is best known for his work scoring many episodes of "The Simpsons", of which he had been the sole composer between 1990 and 2017. Clausen has scored or orchestrated music for more than 30 films and television shows, including "Moonlighting", "The Naked Gun", "ALF" and "Ferris Bueller's Day Off". Clausen received an Honorary Doctorate of Music from the prestigious Berklee College of Music in 1996.

paragraph_text: Muhammad Amin Ibn Abidin (1198–1252 AH / 1783–1836 AD) also known as Imam Ibn Abidin ash-shami was a prominent Islamic scholar and Jurist who lived in the city of Damascus in Syria during the Ottoman era. He was the authority of the fiqh (Islamic jurisprudence) of the Hanafi madhhab (school of law). He was a state employee with the title of Amin al-fatwa. This meant that he was the mufti that people would go to when they had legal questions in Damascus. He composed over 50 works consisting of a major fatwa (legal statement) collection, many treatises, poems, and several commentaries on the works of others.

paragraph_text: The Grans Brewery (Grans Bryggeri AS) is a brewery founded in 1899 in Sandefjord, Norway. The bane was "Sandefjord Bryggeri og Mineralvandfabrik A/S" until 1965. After two generations of Guttorm Gran (senior and junior) in the management, Trygve Christophersen was employed as CEO in 2001.

paragraph_text: In 1466, perhaps 40,000 people died of the plague in Paris. During the 16th and 17th centuries, the plague was present in Paris around 30 per cent of the time. The Black Death ravaged Europe for three years before it continued on into Russia, where the disease was present somewhere in the country 25 times between 1350 to 1490. Plague epidemics ravaged London in 1563, 1593, 1603, 1625, 1636, and 1665, reducing its population by 10 to 30% during those years. Over 10% of Amsterdam's population died in 1623–25, and again in 1635–36, 1655, and 1664. Plague occurred in Venice 22 times between 1361 and 1528. The plague of 1576–77 killed 50,000 in Venice, almost a third of the population. Late outbreaks in central Europe included the Italian Plague of 1629–1631, which is associated with troop movements during the Thirty Years' War, and the Great Plague of Vienna in 1679. Over 60% of Norway's population died in 1348–50. The last plague outbreak ravaged Oslo in 1654.

paragraph_text: Al gran sole carico d'amore ("In the Bright Sunshine Heavy with Love") is an opera (designated as an 'azione scenica') with music by Luigi Nono, based mainly on plays by Bertolt Brecht, but also incorporating texts of Fidel Castro, Che Guevara, Karl Marx, and Vladimir Lenin. Nono himself and Yuri Lyubimov wrote the libretto. It premiered at the Teatro alla Scala on 4 April 1975, conducted by Claudio Abbado. Lyubimov directed the original production. The UK premiere was at the 32nd Edinburgh Festival in 1978. In addition to vocal soloists, chorus and orchestra, the work incorporates taped sounds. This work is a product of Nono's strong political activism through the mid-1970s.

paragraph_text: It is recognised that an epidemiological account of the plague is as important as an identification of symptoms, but researchers are hampered by the lack of reliable statistics from this period. Most work has been done on the spread of the plague in England, and even estimates of overall population at the start vary by over 100% as no census was undertaken between the time of publication of the Domesday Book and the year 1377. Estimates of plague victims are usually extrapolated from figures from the clergy.

paragraph_text: Abu Zayd Abd al-Rahman al-Jazuli al-Tamanarti al-Mghafri (died 1070 AH, 1659/60 AD) was a qadi of the Moroccan town Taroudannt and grand qadi of the Sous area. He is the author of " Fawaid al Jamma bi Isnadi Ouloumi al Oumma", an autobiographical work of great historical value that also includes biographies of his instructors. Appended to this work is a chapter about dreams, "Bab al-rabi".

paragraph_text: He studied under Giacomo Favretto, Alessandro Milesi, and Luigi Nono at the Academy of Fine Arts in his native Venice. In 1873, he exhibited in Venice: "Né sposo né figlio" and "Scena famigliare". In 1877 at Paris, "Les saltimbanques" and "Les pingeons de Saint Marc". He was active as a painter in Venice. Among his watercolors are "Le rondini", exhibited at 1880 at Turin; "Una calle", exhibited at the 1891 Mostra Triennale of the Brera Academy. In 1881 at Milan, displayed the paintings: "Mercante di ventagli"; "At the Predica", "Half-figure of a Girl"; and "Popolana". In 1883 in Rome, exhibited: "The Lovers". He painted "Love Letter", "Una fuga nel 1700"; and "The Dockside of San Marco". He sent to Paris in 1877-1878, the paintings: "Pigeons of St Mark", "El-Mazrama" (Mouchoir of the Sultan), "Los Saltimbanques", and "A venetian - A Daughter of the People".

paragraph_text: The plague theory was first significantly challenged by the work of British bacteriologist J. F. D. Shrewsbury in 1970, who noted that the reported rates of mortality in rural areas during the 14th-century pandemic were inconsistent with the modern bubonic plague, leading him to conclude that contemporary accounts were exaggerations. In 1984 zoologist Graham Twigg produced the first major work to challenge the bubonic plague theory directly, and his doubts about the identity of the Black Death have been taken up by a number of authors, including Samuel K. Cohn, Jr. (2002), David Herlihy (1997), and Susan Scott and Christopher Duncan (2001).

paragraph_text: Christian Ackermann was born in Königsberg. He worked in Riga, Stockholm, and Gdańsk, before becoming active in Tallinn from about 1672 until his death in 1710. In 1675, Ackermann moved to Tallinn and acquired his own workshop. He probably died either in 1710 or a short time later from plague.

paragraph_text: Trigger Happy! is the sole album led by American jazz double bassist Trigger Alpert which was recorded in 1956 for the Riverside label. The album was also issued under Zoot Sims Al Cohn and Tony Scott's names as East Coast Sounds.

Question: How many times did plague occur in Al gran sole carico d'amore's composer's work location?
Answer: 22