paragraph_text: The Black Death was a bubonic plague pandemic, which reached England in June 1348. It was the first and most severe manifestation of the Second Pandemic, caused by Yersinia pestis bacteria. The term ``Black Death ''was not used until the late 17th century.

paragraph_text: Violante is an oil painting attributed to Titian, dated to around 1515 and now held at the Kunsthistorisches Museum in Vienna.

paragraph_text: The plague theory was first significantly challenged by the work of British bacteriologist J. F. D. Shrewsbury in 1970, who noted that the reported rates of mortality in rural areas during the 14th-century pandemic were inconsistent with the modern bubonic plague, leading him to conclude that contemporary accounts were exaggerations. In 1984 zoologist Graham Twigg produced the first major work to challenge the bubonic plague theory directly, and his doubts about the identity of the Black Death have been taken up by a number of authors, including Samuel K. Cohn, Jr. (2002), David Herlihy (1997), and Susan Scott and Christopher Duncan (2001).

paragraph_text: The Black Death, also known as the Great Plague, the Black Plague, or simply the Plague, was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia and peaking in Europe from 1347 to 1351. The bacterium Yersinia pestis, which results in several forms of plague, is believed to have been the cause. The plague created a series of religious, social and economic upheavals, which had profound effects on the course of European history.

paragraph_text: In addition to arguing that the rat population was insufficient to account for a bubonic plague pandemic, sceptics of the bubonic plague theory point out that the symptoms of the Black Death are not unique (and arguably in some accounts may differ from bubonic plague); that transference via fleas in goods was likely to be of marginal significance; and that the DNA results may be flawed and might not have been repeated elsewhere, despite extensive samples from other mass graves. Other arguments include the lack of accounts of the death of rats before outbreaks of plague between the 14th and 17th centuries; temperatures that are too cold in northern Europe for the survival of fleas; that, despite primitive transport systems, the spread of the Black Death was much faster than that of modern bubonic plague; that mortality rates of the Black Death appear to be very high; that, while modern bubonic plague is largely endemic as a rural disease, the Black Death indiscriminately struck urban and rural areas; and that the pattern of the Black Death, with major outbreaks in the same areas separated by 5 to 15 years, differs from modern bubonic plague—which often becomes endemic for decades with annual flare-ups.

paragraph_text: The historian Francis Aidan Gasquet wrote about the 'Great Pestilence' in 1893 and suggested that "it would appear to be some form of the ordinary Eastern or bubonic plague". He was able to adopt the epidemiology of the bubonic plague for the Black Death for the second edition in 1908, implicating rats and fleas in the process, and his interpretation was widely accepted for other ancient and medieval epidemics, such as the Justinian plague that was prevalent in the Eastern Roman Empire from 541 to 700 CE.

paragraph_text: The 2010 Elazığ earthquake was a 6.1 M earthquake that occurred on 8 March 2010 at 02:32 UTC (04:32 local time). The epicentre was Başyurt in Elazığ Province, in eastern Turkey. Initial reports in global media said as many as 57 people had died. By 10 March, reports in the Turkish media placed the death toll at 41 and later, the death toll rose to 42. Another 74 were injured, many after falling and jumping from buildings. A stampede through the streets led to further injuries.

paragraph_text: Informal learning is one of three forms of learning defined by the Organisation for Economic Co-operation and Development (OECD). Informal learning occurs in a variety of places, such as at home, work, and through daily interactions and shared relationships among members of society. For many learners this includes language acquisition, cultural norms and manners. Informal learning for young people is an ongoing process that also occurs in a variety of places, such as out of school time, in youth programs at community centers and media labs.

paragraph_text: The Black Death is thought to have originated in the arid plains of Central Asia, where it then travelled along the Silk Road, reaching Crimea by 1343. From there, it was most likely carried by Oriental rat fleas living on the black rats that were regular passengers on merchant ships. Spreading throughout the Mediterranean and Europe, the Black Death is estimated to have killed 30 -- 60% of Europe's total population. In total, the plague may have reduced the world population from an estimated 450 million down to 350 -- 375 million in the 14th century. The world population as a whole did not recover to pre-plague levels until the 17th century. The plague recurred occasionally in Europe until the 19th century.

paragraph_text: The Black Death ravaged much of the Islamic world. Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. Plague repeatedly struck the cities of North Africa. Algiers lost 30 to 50 thousand inhabitants to it in 1620–21, and again in 1654–57, 1665, 1691, and 1740–42. Plague remained a major event in Ottoman society until the second quarter of the 19th century. Between 1701 and 1750, thirty-seven larger and smaller epidemics were recorded in Constantinople, and an additional thirty-one between 1751 and 1800. Baghdad has suffered severely from visitations of the plague, and sometimes two-thirds of its population has been wiped out.

paragraph_text: Christian Ackermann was born in Königsberg. He worked in Riga, Stockholm, and Gdańsk, before becoming active in Tallinn from about 1672 until his death in 1710. In 1675, Ackermann moved to Tallinn and acquired his own workshop. He probably died either in 1710 or a short time later from plague.

paragraph_text: The Black Death, also known as the Great Plague, the Black Plague, or the Plague, was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia and peaking in Europe from 1347 to 1351. The bacterium Yersinia pestis, which results in several forms of plague, is believed to have been the cause. The plague created a series of religious, social and economic upheavals, which had profound effects on the course of European history.

paragraph_text: In 1466, perhaps 40,000 people died of the plague in Paris. During the 16th and 17th centuries, the plague was present in Paris around 30 per cent of the time. The Black Death ravaged Europe for three years before it continued on into Russia, where the disease was present somewhere in the country 25 times between 1350 to 1490. Plague epidemics ravaged London in 1563, 1593, 1603, 1625, 1636, and 1665, reducing its population by 10 to 30% during those years. Over 10% of Amsterdam's population died in 1623–25, and again in 1635–36, 1655, and 1664. Plague occurred in Venice 22 times between 1361 and 1528. The plague of 1576–77 killed 50,000 in Venice, almost a third of the population. Late outbreaks in central Europe included the Italian Plague of 1629–1631, which is associated with troop movements during the Thirty Years' War, and the Great Plague of Vienna in 1679. Over 60% of Norway's population died in 1348–50. The last plague outbreak ravaged Oslo in 1654.

paragraph_text: Other forms of plague have been implicated by modern scientists. The modern bubonic plague has a mortality rate of 30–75% and symptoms including fever of 38–41 °C (100–106 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Left untreated, of those that contract the bubonic plague, 80 percent die within eight days. Pneumonic plague has a mortality rate of 90 to 95 percent. Symptoms include fever, cough, and blood-tinged sputum. As the disease progresses, sputum becomes free flowing and bright red. Septicemic plague is the least common of the three forms, with a mortality rate near 100%. Symptoms are high fevers and purple skin patches (purpura due to disseminated intravascular coagulation). In cases of pneumonic and particularly septicemic plague, the progress of the disease is so rapid that there would often be no time for the development of the enlarged lymph nodes that were noted as buboes.

paragraph_text: In 1726, however, a re-establishment took place through Jakob van Schuppen as "K.k. Hofacademie of the painters, sculptor and architecture", which still exists. Peter Strudel is considered as a founder of the oldest art academy of central Europe, the Academy of Fine Arts Vienna. One year before the death of Strudel, the "Strudelhof" included a plague house, where those afflicted by the epidemic were treated and quarantined.

paragraph_text: Medical knowledge had stagnated during the Middle Ages. The most authoritative account at the time came from the medical faculty in Paris in a report to the king of France that blamed the heavens, in the form of a conjunction of three planets in 1345 that caused a "great pestilence in the air". This report became the first and most widely circulated of a series of plague tracts that sought to give advice to sufferers. That the plague was caused by bad air became the most widely accepted theory. Today, this is known as the Miasma theory. The word 'plague' had no special significance at this time, and only the recurrence of outbreaks during the Middle Ages gave it the name that has become the medical term.

paragraph_text: At the onset of clinical death, consciousness is lost within several seconds. Measurable brain activity stops within 20 to 40 seconds. Irregular gasping may occur during this early time period, and is sometimes mistaken by rescuers as a sign that CPR is not necessary.  During clinical death, all tissues and organs in the body steadily accumulate a type of injury called ischemic injury.

paragraph_text: Acral necrosis is a symptom common in bubonic plague. The striking black discoloration of skin and tissue, primarily on the extremities (``acral ''), is commonly thought to have given rise to the name`` Black Death,'' associated both with the disease and the pandemic which occurred in the 14th century. The term in fact came from the figural sense of ``black '', that is ghastly, lugubrious or dreadful.

paragraph_text: The Martyrdom of Saint Lawrence is a 1558 painting by Titian, now in the church of I Gesuiti in Venice. It so impressed Philip II of Spain that he commissioned a second version in 1567 for the basilica at El Escorial.

paragraph_text: The 2013 Houphouët-Boigny stampede occurred as crowds departed a New Year's Eve fireworks display in the early hours of 1 January 2013 near the Félix Houphouët-Boigny Stadium in Abidjan, Ivory Coast. It resulted in 61 deaths and over 200 injuries, mostly women and children. This was the second time in four years that a fatal stampede occurred at the stadium.

Question: How many times did plague occur in the place of death of the creator of Violante?
Answer: 22