Hüma Hatun
Hüma Hatun (1410 ‒ September 1449) was the fourth wife of Ottoman Sultan Murad II and mother of Mehmed II and the grandmother of Bayezid II.
Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.
Anne Denman
Anne Denman( 1587–1661) was born in Olde Hall, Retford, Nottinghamshire.
Through a fortunate second marriage with Thomas Aylesbury, she became the grandmother of Lady Anne Hyde, Duchess of York and great- grandmother of Queen Mary II and Queen Anne.
Colin Campbell, 1st Earl of Argyll
Colin Campbell, 1st Earl of Argyll (c. 1433 – 10 May 1493), was a medieval Scottish nobleman, peer, and politician.
He was the son of Archibald Campbell, Master of Campbell and Elizabeth Somerville.
He had the sobriquet Colin Mulle, Bold Earl Colin.
Mona Hopton Bell
Mona Hopton Bell( 1867- 1940) was a British artist, best known for her portraits of civic figures.
She was the grandmother of the painter Jean H. Bell.
Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Gülbahar Hatun (wife of Mehmed II)
Gülbahar Hatun( 1432 – 1492) was the consort of Sultan Mehmed II, and mother of Sultan Bayezid II of the Ottoman Empire and the grandmother of Selim I.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Iseabail Ní Mheic Cailéin
Iseabail Ní Mheic Cailéin, Gaelic noblewoman and poet, fl. 1500.
A daughter of Colin Campbell, 1st Earl of Argyll (died 1493).
Three poems by her are preserved in the Book of the Dean of Lismore - "Atá fleasgach ar mo thíÉistibh, a Luchd an Tighe-se" and "Is mairg dá ngalar an grádh".
Thomas Owen Clancy Clancy notes that "Éistibh, a Luchd an Tighe-seis a fairly obscene boast to the court circle on the size and potency of her household priest's penis.
The authenticity of the attribution to Iseabail has been questioned, but without substantial grounds."

Question: Who is the paternal grandmother of Iseabail Ní Mheic Cailéin?
Answer: Elizabeth Somerville