Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.
Juan de Aragón y de Jonqueras, 2nd count of Ribagorza
Juan de Aragón y de Jonqueras, 2nd Count of Ribagorza,( 27 March 1457 in Benabarre, Spain – 5 July 1528 in Monzón, Spain) was a Viceroy of Naples( 1507 – 1509), replacing Gonzalo Fernández de Córdoba.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Juan Alfonso de la Cerda
Juan Alfonso de la Cerda
( France, 1295- August 7, 1347) was Lord of Gibraleón, Huelva, Real de Manzanares and Deza.
He was the son of Alfonso de la Cerda, grandson of Ferdinand de la Cerda.
His mother was Matile of Brienne, daughter of John I of Brienne, Count of Eu. He married Maria Alfonso de Portugal( illegitimate daughter of King Denis of Portugal).
He served under Alfonso XI of Castile in the Siege of Algeciras( 1342- 1344), which culminated in the city's surrender in 1344.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Hernando de Aragón
Hernando de Aragón y de Gurrea, OCist( 25 July 1498 – 29 January 1575), Archbishop of Zaragoza and Lieutenant General of Aragon, was an Aragonese humanist and historian.
Alfonso de Talavera
Alfonso de Talavera, O.S.H. or Alfonso de Guzman was a Roman Catholic prelate who served as the first Bishop of Comayagua( 1531 – 1540).
Alfonso de Aragón y de Escobar
Alfonso (or Alonso) de Aragon y de Escobar (1417–1495), Duke of Villahermosa, Count of Ribagorza and Cortes and Grand Master of the Order of Calatrava, was an illegitimate son of John II of Aragon and Leonor de Escobar, one of his mistresses.
His brothers and half brothers included Prince Charles of Trastámara and Viana (Charles IV of Navarre) and King Ferdinand II of Aragon, called the Catholic.
On August 18, 1443 he was elected "Master of the Order of Calatrava" and dismissed on September 19, 1445, overtaken by Pedro Girón.
Received the title of count of Ribagorza by his father John II in Monzón, and resigned on November 27, 1469 to be succeeded by his first son Fernando.
He fought in the War of the Castilian Succession.
Capture of the Catalan castle of Amposta gave him fame during the war.
He again led a group of skilled siege engineers in the Siege of Burgos in 1475.
In 1475 he was named Duke of Villahermosa by his father John II of Aragon as a reward for his loyalty and military value.
Alfonso of Aragon and Escobar died in Linares in 1485, not long after making to Pizarra, Málaga.
John II of Aragon
John II (Catalan: "Joan II", Aragonese: "Chuan II" and), called the Great ("el Gran") or the Faithless ("el Sense Fe")
(29 June 1398 – 20 January 1479), was the King of Navarre through his wife ("jure uxoris") from 1425 and the King of Aragon in his own right from 1458 until his death.
He was the son of Ferdinand I and his wife Eleanor of Alburquerque.
John was also King of Sicily from 1458-1468.

Question: Who is the paternal grandmother of Alfonso De Aragón Y De Escobar?
Answer: Eleanor of Alburquerque