Carlo de' Medici (cardinal)
Carlo de' Medici( 19 March 1595 – 17 June 1666) was the son of Ferdinando I de' Medici, Grand Duke of Tuscany and Christina of Lorraine.
Ferdinando II de' Medici, Grand Duke of Tuscany
Ferdinando II de' Medici (14 July 1610 – 23 May 1670) was grand duke of Tuscany from 1621 to 1670.
He was the eldest son of Cosimo II de' Medici and Maria Maddalena of Austria.
His 49-year rule was punctuated by the beginning of Tuscany's long economic decline.
He married Vittoria della Rovere, a first cousin, with whom he had two children who reached adulthood: Cosimo III
de' Medici, his eventual successor, and Francesco Maria de' Medici, Duke of Rovere and Montefeltro, a cardinal.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Leopoldo de' Medici
Leopoldo de' Medici (6 November 1617 – 10 November 1675) was an Italian cardinal, scholar, patron of the arts and Governor of Siena.
He was the brother of Ferdinando II de' Medici, Grand Duke of Tuscany.
Giovanni di Bicci de' Medici
Giovanni di Bicci de' Medici( c. 1360 – February 1429) was an Italian banker and founder of the Medici Bank.
While other members of the Medici family, such as Chiarissimo di Giambuono de' Medici, who served in the Signoria of Florence in 1201, and Salvestro de' Medici, who was implicated in the Ciompi Revolt of 1378, are of historical interest, it was Giovanni's founding of the family bank that truly initiated the family's rise to power in Florence.
He was the father of Cosimo de' Medici and Lorenzo de' Medici, and an ancestor of other notable Medici rulers.
For example, he was the grandfather of Piero di Cosimo de' Medici; the great- grandfather of Lorenzo de' Medici( the Magnificent); and the great- great- great- grandfather of Cosimo I de' Medici, Grand Duke of Tuscany.
Nannina de' Medici
Nannina de' Medici( 14 February 1448 – 14 May 1493), born Lucrezia de' Medici, was the second daughter of Piero di Cosimo de' Medici and Lucrezia Tornabuoni.
She was thus the elder sister of Lorenzo de' Medici.
She married Bernardo Rucellai.
Her father's name was Piero, so she is sometimes known as Lucrezia di Piero de' Medici.
Maria Cristina de' Medici
Maria Cristina de 'Medici (24 August 1609 - 9 August 1632) was a Tuscan princess and the first born child of Cosimo II de' Medici, Grand Duke of Tuscany.
Cosimo II de' Medici, Grand Duke of Tuscany
Cosimo II de' Medici (12 May 1590 – 28 February 1621) was Grand Duke of Tuscany from 1609 until his death.
He was the elder son of Ferdinando
I de' Medici, Grand Duke of Tuscany, and Christina of Lorraine.
For the majority of his twelve-year reign, he delegated the administration of Tuscany to his ministers.
He is best remembered as the patron of Galileo Galilei, his childhood tutor.
Giancarlo de' Medici
Giancarlo de' Medici (24 July 1611 – 22 January 1663) was an Italian cardinal of the House of Medici.
He was the second son of Grand Duke Cosimo II of Tuscany and his wife, Maria Maddalena of Austria, and the brother of Ferdinando II de' Medici, Grand Duke of Tuscany.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.

Question: Who is the paternal grandmother of Ferdinando Ii De' Medici, Grand Duke Of Tuscany?
Answer: Christina of Lorraine