Louis, Duke of Joyeuse
Louis de Lorraine, Duke of Joyeuse( 11 January 1622 – 27 September 1654, Paris) was a younger son of Charles, Duke of Guise and Henriette Catherine de Joyeuse.
Charles, Duke of Mayenne
Charles of Lorraine, Duke of Mayenne (26 March 1554 – 3 October 1611), or Charles de Guise, was a French nobleman of the house of Guise and a military leader of the Catholic League, which he headed during the French Wars of Religion, following the assassination of his brothers at Blois in 1588.
In 1596, when he made peace with Henri of Navarre, the wars were essentially at an end.
He was the second son of Francis of Lorraine, Duke of Guise and Anna d'Este, the daughter of Ercole II d'Este, Duke of Ferrara and Renée of France.
Antoinette de Bourbon
Antoinette de Bourbon Duchess of Guise( 25 December 1494 – 22 January 1583) was a French noblewoman of the House of Bourbon.
She was the wife of Claude of Lorraine, Duke of Guise.
Through her eldest daughter, Mary of Guise, she was the maternal grandmother of Mary, Queen of Scots.
Henri I, Duke of Nemours
Henri of Savoy( 2 November 157210 July 1632), called originally Marquis de Saint- Sorlin, was the son of Jacques of Savoy and Anna d' Este, the widow of François de Lorraine, Duke of Guise.
He succeeded his brother Charles Emmanuel as Duke of Nemours.
In 1588 he took the marquisate of Saluzzo from the French for his cousin, the Duke of Savoy.
The princes of Guise, his half- brothers, induced him to join the League, and in 1591 he was made governor of Dauphiné in the name of that faction.
He made his submission to Henry IV in 1596.
After quarrelling with the duke of Savoy he withdrew to Burgundy and joined the Spaniards in their war against Savoy.
After peace had been proclaimed on November 14, 1616, he retired to the French court.
After his death, he was succeeded by his eldest son, Louis; on the death of Louis in 1641 by his second son Charles Amadeus; and on Charles's death in 1651 by his third son Henri.
All three were the sons of his wife Anne de Lorraine( 1600 – 1638), daughter of Charles de Lorraine, Duke of Aumale.
Marie de Lorraine, Duchess of Guise
Marie de Lorraine( 15 August 1615 – 3 March 1688) was the daughter of Charles de Lorraine, Duke of Guise and Henriette Catherine de Joyeuse and the last member of the House of Guise, a branch of the House of Lorraine.
Élisabeth Marguerite d'Orléans
Élisabeth Marguerite d'Orléans (26 December 1646 - 17 March 1696), known as Isabelle d'Orléans, was the Duchess of Alençon and, during her husband's lifetime, Duchess of Angoulême.
She was a daughter of Gaston d'Orléans and a first cousin of Louis XIV of France.
She has no descendants today.
She was "suo jure" Duchess of Alençon and Angoulême.
René, Marquis of Elbeuf
René of Guise, Marquis d' Elbeuf( 14 August 1536 – 14 December 1566) was the youngest son of Claude of Lorraine, Duke of Guise and Antoinette of Bourbon- Vendôme.
René was born at Joinville, Haute- Marne.
He married Louise de Rieux( 1531 – c. 1570) on 3 February 1555.
They had two children:
He served as French ambassador to Scotland, and accompanied his niece Mary, Queen of Scots on her entrance to that country in 1561.
He was also a patron of the arts, particularly of composer Pierre Clereau of Lorraine.
Charles, Duke of Guise
Charles de Lorraine, 4th Duke of Guise( 2 August 1571 – 30 September 1640) was the son of Henry I, Duke of Guise and Catherine of Cleves.
Nicolas, Duke of Mercœur
Nicolas of Lorraine, Duke of Mercœur (16 October 1524 – 23 January 1577) was the second son of Antoine, Duke of Lorraine and Renée de Bourbon.
François Joseph, Duke of Guise
François Joseph de Lorraine (Paris, 28 August 1670 – 16 March 1675, Paris), Duke of Guise, Duke of Alençon and Duke of Angoulême, was the only son of Louis Joseph de Lorraine, Duke of Guise and Élisabeth Marguerite d'Orléans, "suo jure" duchess of Alençon.

Question: When did François Joseph, Duke Of Guise's mother die?
Answer: 17 March 1696