Giuliano de' Medici
Giuliano de' Medici (25 March 1453 – 26 April 1478) was the second son of Piero de' Medici (the Gouty) and Lucrezia Tornabuoni.
As co-ruler of Florence, with his brother Lorenzo the Magnificent, he complemented his brother's image as the "patron of the arts" with his own image as the handsome, sporting, "golden boy."
Anne Denman
Anne Denman( 1587–1661) was born in Olde Hall, Retford, Nottinghamshire.
Through a fortunate second marriage with Thomas Aylesbury, she became the grandmother of Lady Anne Hyde, Duchess of York and great- grandmother of Queen Mary II and Queen Anne.
Mona Hopton Bell
Mona Hopton Bell( 1867- 1940) was a British artist, best known for her portraits of civic figures.
She was the grandmother of the painter Jean H. Bell.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.
Hüma Hatun
Hüma Hatun (1410 ‒ September 1449) was the fourth wife of Ottoman Sultan Murad II and mother of Mehmed II and the grandmother of Bayezid II.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Pope Clement VII
Pope Clement VII
(26 May 1478 – 25 September 1534), born
Giulio di Giuliano de' Medici, was head of the Catholic Church and ruler of the Papal States from 19 November 1523 to his death on 25 September 1534.
“The most unfortunate of the Popes,” Clement VII’s reign was marked by a rapid succession of political, military, and religious struggles — many long in the making — which had far-reaching consequences for Christianity and world politics.
Elected in 1523 at the end of the Italian Renaissance, Clement VII came to the papacy with a high reputation as a statesman.
He'd served with distinction as chief advisor to Pope Leo X (1513-1521), Pope Adrian VI (1522-1523), and commendably as gran maestro of Florence (1519-1523).
Assuming leadership at a time of crisis, with the Protestant Reformation spreading; the Church nearing bankruptcy; and large, foreign armies invading Italy, Clement VII initially tried to unite Christendom by making peace among the many Christian leaders then at odds.
He later attempted to liberate Italy from foreign occupation, believing that it threatened the Church's freedom.
The complex political situation of the 1520s thwarted Clement's efforts.
Inheriting daunting challenges, including Martin Luther’s Protestant Reformation in Northern Europe; a vast power struggle in Italy between Europe’s two most powerful kings, Holy Roman Emperor Charles V and Francis I of France, each of whom demanded that the Pope choose a side; and Turkish invasions of Eastern Europe led by Suleiman the Magnificent; Clement's problems were exacerbated by King Henry VIII of England’s contentious divorce, resulting in England breaking away from the Catholic Church; and in 1527, souring relations with Emperor Charles V leading to the violent Sack of Rome, during which the Pope was imprisoned.
After escaping confinement in the Castel Sant'Angelo, Clement — with few economic, military, or political options remaining — compromised the Church's and Italy's independence by allying with his former jailor, Emperor Charles V.
In contrast to his tortured Papacy, Clement VII was personally respectable and devout, possessing a “dignified propriety of character,”
“great acquirements both theological and scientific,” as well as “extraordinary address and penetration — Clement VII, in serener times, might have administered the Papal power with high reputation and enviable prosperity.
But with all of his profound insight into the political affairs of Europe, Clement does not seem to have comprehended the altered position of the Pope” in relation to Europe’s emerging nation-states and Protestantism.
In matters of science, Clement VII is best known for personally approving, in 1533, Nicolaus Copernicus’s theory that the Earth revolves around the Sun — 99 years before Galileo Galilei’s heresy trial for similar ideas.
Ecclesiastically, Clement VII is remembered for issuing orders protecting Jews from the Inquisition, approving the Capuchin Franciscan Order, and securing the island of Malta for the Knights of Malta.
Gülbahar Hatun (wife of Mehmed II)
Gülbahar Hatun( 1432 – 1492) was the consort of Sultan Mehmed II, and mother of Sultan Bayezid II of the Ottoman Empire and the grandmother of Selim I.

Question: Who is Pope Clement Vii's paternal grandmother?
Answer: Lucrezia Tornabuoni