Giacomo II Crispo
Giacomo II Crispo (or Jacopo) (1426–1447) was the thirteenth Duke of the Archipelago, etc., from 1433 to 1447.
He was the son of twelfth Duke John II Crispo and "Nobil Donna" Francesca Morosini, Patrizia Veneta.
He was a minor when he succeeded to the throne, and during his minority, the Duchy was ruled by his mother Francesca, described as a "masterful woman", who continued to influence in the affairs of state during the reign of her son and grandson until the accession of William II to the throne in 1453.
The reign of Giacomo II was reportedly a peaceful and prosperous one, as the Ottomans were occupied in Hungary, and Venice included the Duchy in their protection in their peace treaty with the Ottomans in 1446.
He married in 1444 Ginevra Gattilusio, daughter of Dorino
I of Lesbos, and wife Orietta Doria, and had two children:
John Westley
Rev. John Westley( 1636 – 78) was an English nonconformist minister.
He was the grandfather of John Wesley( founder of Methodism).
Kaya Alp
Kaya Alp was, according to Ottoman tradition, the son of Kızıl Buğa and the father of Suleyman Shah, who was, in turn, the grandfather of Ertuğrul, and the great grandfather of the Ottoman Empire founder, Osman I.
Gian Giacomo Crispo
Gian Giacomo Crispo (1446–1453) was the fourteenth Duke of the Archipelago, etc., from 1447 to 1453, son of the thirteenth Duke Giacomo II Crispo and Ginevra Gattilusio.
Antonio Crispo, Governor of the Duchy of the Archipelago
Antonio Crispo( died after 1505) was a governor of the Duchy of the Archipelago between 1496 and 1505.
He was the son of Giacomo Crispo.
He married NN and had a son:
Guillaume Wittouck
Guillaume Wittouck( 1749- 1829) was a Belgian lawyer and High Magistrate.
He was the Grandfather of industrialist Paul Wittouck.
Lyon Cohen
Lyon Cohen( 1868–1937) was a Polish- born Canadian businessman and a philanthropist.
He was the grandfather of singer/ poet Leonard Cohen.
Prithvipati Shah
Prithvipati Shah( ?–1716) was the king of the Gorkha Kingdom in the Indian subcontinent, present- day Nepal.
He was the grandfather of Nara Bhupal Shah.
Abd al-Muttalib
Abd al- Muttalib Shaybah ibn Hashim( c. 497 – 578) was the grandfather of Islamic prophet Muhammad.
Gian Giacomo Teodoro Trivulzio
Giovanni( Gian) Giacomo Teodoro Trivulzio
( 1597 – 3 August 1656) was an Italian Cardinal who held several high functions in service of the Spanish Crown.
Trivulzio was born and died in Milan, Duchy of Milan.
He was the son of Carlo Emanuele Teodoro Trivulzio, Count of Melzo, who died when Gian Giacomo was still very young, and Catherina Gonzaga.
His sister was Ippolita Trivulzio.
In 1615 he married Giovanna Maria Grimaldi, daughter of Hercule, Lord of Monaco .< br>
They had two daughters and one son:
When his wife died in 1620, Gian Giacomo entered the Church.
In 1629, he became cardinal .< br>
In 1642 he became Viceroy of Aragon, and Grandee of Spain.
He participated in the Papal conclave, 1644, which finally chose Pope Innocent X, and in the Papal conclave, 1655, which elected Pope Alexander VII, and where Gian Giacomo as protodeacon gave the Habemus Papam announcement.
Between 1647 and 1649 he was Viceroy of Sicily and between 1649 and 1651 Viceroy of Sardinia.
In April 1656 he became interim Governor of the Duchy of Milan, a post he held until his death.
He died in Milan on 3 August 1656 and was buried in the family vault in the Santo Stefano church.

Question: Who is the paternal grandfather of Gian Giacomo Crispo?
Answer: John II Crispo