Joanna of Austria, Princess of Portugal
Joanna of Austria (in Castilian, "doña Juana de Austria"; in Portuguese, "Dona Joana de Áustria", 24 June 1535 – 7 September 1573) was a Princess of Portugal by marriage to John Manuel, Prince of Portugal.
She served as regent of Spain to her brother Philip II of Spain during his trip to England to marry Mary I in 1554-1556, and from 1556 to 1559.
She was the mother of King Sebastian of Portugal.
Afonso, Prince of Portugal (1526)
Afonso, Prince of Portugal was the first son of king John III of Portugal and his queen, Catherine of Austria.
He was the Prince of Portugal but died in the same year he was born, in 1526.
João Manuel, Prince of Portugal
João Manuel, Prince of Portugal( 3 June 1537 – 2 January 1554) was a Portuguese" infante"( prince), the eighth son of King John III of Portugal by his wife Catherine of Austria, daughter of Philip I of Castile and Joanna of Castile.
As the heir to the throne he was styled Prince of Portugal.
Diana Guardato
Diana Guardato was a member of the aristocratic Patrician Guardato family, and had three children with King Ferdinand I: Diana Guardato is the 16th- Great Grandmother of His Royal Highness Albert II of Belgium, 15th- Great Grandmother of His Majesty Juan Carlos
I of Spain, 17th- Great Grandmother of Philippe of Belgium, 14th- Great Grandmother of His Majesty Manuel II of Portugal, 16th- Great Grandmother of Grand Duke Henri, as well as many others.
Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
John III of Portugal
John III (7 June 1502 – 11 June 1557) nicknamed The Colonizer (Portuguese: "o Colonizador")
was the King of Portugal and the Algarves from 13 December 1521 to 11 June 1557.
He was the son of King Manuel I and Maria of Aragon, the third daughter of King Ferdinand II of Aragon and Queen Isabella
I of Castile.
John succeeded his father in 1521, at the age of nineteen.
During his rule, Portuguese possessions were extended in Asia and in the New World through the Portuguese colonization of Brazil.
John III's policy of reinforcing Portugal's bases in India (such as Goa) secured Portugal's monopoly over the spice trade of cloves and nutmeg from the Maluku Islands, as a result of which John III has been called the "Grocer King".
On the eve of his death in 1557, the Portuguese empire had a global dimension and spanned almost 1 billion acres (about 4 million square kilometers).
During his reign, the Portuguese became the first Europeans to make contact with both China, under the Ming dynasty, and Japan, during the Muromachi period.
He abandoned Muslim territories in North Africa in favor of trade with India and investment in Brazil.
In Europe, he improved relations with the Baltic region and the Rhineland, hoping that this would bolster Portuguese trade.
Philip, Prince of Portugal
Filipe, Prince of Portugal( 25 March 1533 – 29 April 1539), was the Prince of Portugal from 1537 to his death in 1539.
He was the sixth child son of king John III of Portugal and Catherine of Austria.
In 1537, he succeeded his brother Prince Manuel as Prince of Portugal, after his premature death.
However, after his own premature death, two years later, after reaching six years old, his younger brother Infante João Manuel became the next Prince of Portugal.
Manuel, Prince of Portugal (1531–1537)
Manuel, Prince of Portugal (11 November 1531 – 14 April 1537), was the Prince of Portugal from 1535 to his death in 1537.
He was the fifth child son of king John III of Portugal and Catherine of Austria.
In 1535, his father officially designated him as Prince of Portugal, taking the place of his eldest sister Infanta Maria Manuela.
However, after his premature death at five years old, his younger brother Infante Filipe became the next Prince of Portugal.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.

Question: Who is the paternal grandmother of Manuel, Prince Of Portugal (1531–1537)?
Answer: Maria of Aragon