Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Anne Denman
Anne Denman( 1587–1661) was born in Olde Hall, Retford, Nottinghamshire.
Through a fortunate second marriage with Thomas Aylesbury, she became the grandmother of Lady Anne Hyde, Duchess of York and great- grandmother of Queen Mary II and Queen Anne.
Francis, Duke of Anjou
Francis, Duke of Anjou and Alençon ("Hercule François"; 18 March 1555 – 10 June 1584) was the youngest son of King Henry II of France and Catherine de' Medici.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Louis II, Cardinal of Guise
Louis II, Cardinal of Guise( 6 July 1555, Dampierre – 24 December 1588, Château de Blois), was the third son of Francis, Duke of Guise, and Anna d' Este.
Philippe, Duke of Anjou
Philippe of France, Duke of Anjou( 30 August 1730 – 7 April 1733) was a French prince and the second son of king Louis XV of France and Marie Leszczyńska.
He was styled Duke of Anjou from birth.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Catherine de' Medici
Catherine de' Medici (13 April 1519 – 5 January 1589), was an Italian noblewoman who was queen consort of France from 1547 until 1559, by marriage to King Henry II, and Queen mother of kings Francis II, Charles IX and Henry III from 1559 to 1589.
The years during which her sons reigned have been called "the age of Catherine de' Medici" as she had extensive, if at times varying, influence in the political life of France.
She was born in Florence to Lorenzo de’ Medici, Duke of Urbino and Madeleine de La Tour d'Auvergne.
In 1533, at the age of fourteen, Catherine married Henry, second son of King Francis I and Queen Claude of France.
Catherine's marriage was arranged by her uncle Pope Clement VII.
Henry excluded Catherine from participating in state affairs and instead showered favors on his chief mistress, Diane de Poitiers, who wielded much influence over him.
Henry's death thrust Catherine into the political arena as mother of the frail 15-year-old King Francis II.
When he died in 1560, she became regent on behalf of her 10-year-old son King Charles IX and was granted sweeping powers.
From 1560 to 1563, she ruled France as regent for her son Charles IX, King of France.
After Charles died in 1574, Catherine played a key role in the reign of her third son, Henry III.
He dispensed with her advice only in the last months of her life (he would outlive her by seven months).
Catherine's three sons reigned in an age of almost constant civil and religious war in France.
The problems facing the monarchy were complex and daunting but Catherine was able to keep the monarchy and the state institutions functioning even at a minimum level.
At first, Catherine compromised and made concessions to the rebelling Calvinist Protestants, or Huguenots, as they became known.
She failed, however, to grasp the theological issues that drove their movement.
Later she resorted, in frustration and anger, to hard-line policies against them.
In return, she came to be blamed for the excessive persecutions carried out under her sons' rule, in particular for the St. Bartholomew's Day massacre of 1572, in which thousands of Huguenots were killed in Paris and throughout France.
Some historians have excused Catherine from blame for the worst decisions of the crown, though evidence for her ruthlessness can be found in her letters.
In practice, her authority was always limited by the effects of the civil wars.
Her policies, therefore, may be seen as desperate measures to keep the Valois monarchy on the throne at all costs, and her patronage of the arts as an attempt to glorify a monarchy whose prestige was in steep decline.
Without Catherine, it is unlikely that her sons would have remained in power.
According to Mark Strage, one of her biographers, Catherine was the most powerful woman in 16th-century Europe.
Marie of Brittany, Viscountess of Rohan
Marie of Brittany( 1444 – 1506) was the younger daughter of Francis I, Duke of Brittany, by Isabella, daughter of King James I of Scotland.
She was married to John II, Viscount of Rohan and Count of Porhoët.
Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.

Question: Who is the maternal grandmother of Francis, Duke Of Anjou?
Answer: Madeleine de La Tour d'Auvergne