Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Peter III of Aragon
Peter III of Aragon( November 1285) was King of Aragon, King of Valencia( as Peter I), and Count of Barcelona( as) from 1276 to his death.
At the invitation of some rebels, he conquered the Kingdom of Sicily and became King of Sicily in 1282, pressing the claim of his wife, Constance II of Sicily, uniting the kingdom to the crown.
Constance of Sicily, Queen of Aragon
Constance II of Sicily was Queen consort of Aragon as the wife of Peter III of Aragon and a pretender to the Kingdom of Sicily from 1268 to 1285.
She was the only daughter of Manfred of Sicily and his first wife, Beatrice of Savoy.
Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Manfred, King of Sicily
Manfred (123226 February 1266) was the last King of Sicily from the Hohenstaufen dynasty, reigning from 1258 until his death.
The natural son of the Holy Roman Emperor Frederick II, Manfred became regent over the kingdom of Sicily on behalf of his nephew Conradin in 1254.
As regent he subdued rebellions in the kingdom, until in 1258 he usurped Conradin's rule.
After an initial attempt to appease pope Innocent IV he took up the ongoing conflict between the Hohenstaufens and the papacy through combat and political alliances.
He defeated the papal army at Foggia on 2 December 1254.
Excommunicated by three successive popes, Manfred was the target of a Crusade (1255–66) called first by Pope Alexander IV and then by Urban IV.
Nothing came of Alexander's call, but Urban enlisted the aid of Charles of Anjou in overthrowing Manfred.
Manfred was killed during his defeat by Charles at the Battle of Benevento, and Charles assumed kingship of Sicily.
Frederick II, Holy Roman Emperor
Frederick II (26 December 1194 – 13 December 1250) was King of Sicily from 1198, King of Germany from 1212, King of Italy and Holy Roman Emperor from 1220 and King of Jerusalem from 1225.
He was the son of emperor Henry VI of the Hohenstaufen dynasty and of Constance, heiress to the Norman kings of Sicily.
His political and cultural ambitions were enormous as he ruled a vast area, beginning with Sicily and stretching through Italy all the way north to Germany.
As the Crusades progressed, he acquired control of Jerusalem and styled himself its king.
However, the Papacy became his enemy, and it eventually prevailed.
Viewing himself as a direct successor to the Roman emperors of antiquity, he was Emperor of the Romans from his papal coronation in 1220 until his death; he was also a claimant to the title of King of the Romans from 1212 and unopposed holder of that monarchy from 1215.
As such, he was King of Germany, of Italy, and of Burgundy.
At the age of three, he was crowned King of Sicily as a co-ruler with his mother, Constance of Hauteville, the daughter of Roger II of Sicily.
His other royal title was King of Jerusalem by virtue of marriage and his connection with the Sixth Crusade.
Frequently at war with the papacy, which was hemmed in between Frederick's lands in northern Italy and his Kingdom of Sicily (the "Regno") to the south, he was excommunicated four times and often vilified in pro-papal chronicles of the time and after.
Pope Gregory IX went so far as to call him an Antichrist.
Speaking six languages (Latin, Sicilian, Middle High German, Langues d'oïl, Greek and Arabic), Frederick was an avid patron of science and the arts.
He played a major role in promoting literature through the Sicilian School of poetry.
His Sicilian royal court in Palermo, beginning around 1220, saw the first use of a literary form of an Italo-Romance language, Sicilian.
The poetry that emanated from the school had a significant influence on literature and on what was to become the modern Italian language.
He was also the first king to formally outlaw trial by ordeal, which had come to be viewed as superstitious.
After his death his line did not survive, and the House of Hohenstaufen came to an end.
Furthermore, the Holy Roman Empire entered a long period of decline from which it did not completely recover until the reign of Charles V, 250 years later.
Historian Donald Detwiler wrote:
Anne Denman
Anne Denman( 1587–1661) was born in Olde Hall, Retford, Nottinghamshire.
Through a fortunate second marriage with Thomas Aylesbury, she became the grandmother of Lady Anne Hyde, Duchess of York and great- grandmother of Queen Mary II and Queen Anne.
Roger II of Sicily
Roger II( 22 December 1095 – 26 February 1154) was King of Sicily and Africa, son of Roger I of Sicily and successor to his brother Simon.
He began his rule as Count of Sicily in 1105, became Duke of Apulia and Calabria in 1127, then King of Sicily in 1130 and King of Africa in 1148 ..
By the time of his death at the age of 58, Roger had succeeded in uniting all the Norman conquests in Italy into one kingdom with a strong centralized government.
Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.

Question: Who is the paternal grandmother of Manfred, King Of Sicily?