John I, Lord of Polanen
John I, Lord of Polanen( – 26 September 1342) was Lord of Polanen, Lord of De Lek and Lord of Breda.
Nicholas Crispo, Lord of Syros
Nicholas Crispo, Patrizio Veneto (or "Niccolò"; 1392–1450), became Lord of Syros in 1420 and Regent of the Duchy of the Archipelago between 1447 and 1450.
He was a son of Francesco I Crispo, tenth Duke of the Archipelago, and wife Fiorenza I Sanudo, Lady of Milos, and brother of Dukes Giacomo I, John II and William II.
He married in 1413 Princess Valenza-Eudokia Komnena and had ten children:
Kaya Alp
Kaya Alp was, according to Ottoman tradition, the son of Kızıl Buğa and the father of Suleyman Shah, who was, in turn, the grandfather of Ertuğrul, and the great grandfather of the Ottoman Empire founder, Osman I.
John II, Lord of Polanen
John III, Lord of Polanen( – 3 November 1378 in Breda) was Lord of Polanen, Lord of De Lek and Lord of Breda.
Anthony Crispo, Lord of Syros
Anthony Crispo (or "Antonio"; 1429/1430 - 1494), became Lord of Syros in 1463 after his older brother Francesco's death.
He was the youngest son of Nicholas Crispo, Lord of Syros, and wife Valenza-Eudokia Komnena, and brother of Francesco II, sixteenth Duke of the Archipelago.
He married ... de Paterno, without issue.
Henry Krause
Henry J." Red" Krause, Jr.( August 28, 1913 – February 20, 1987) was an American football offensive lineman in the National Football League for the Brooklyn Dodgers and the Washington Redskins.
He played college football at St. Louis University.
He is the grandfather of Jennifer Krause
He is the great grandfather of Payton Hoeing
Abd al-Muttalib
Abd al- Muttalib Shaybah ibn Hashim( c. 497 – 578) was the grandfather of Islamic prophet Muhammad.
Fred Le Deux
Frederick" Fred" Le Deux( born 4 December 1934) was an Australian rules footballer who played with Geelong in the Victorian Football League( VFL).
He is the grandfather of Tom Hawkins.
Angelo I Gozzadini
Angelo I Gozzadini( died between 1468 and 1476) was Lord of Kythnos.
He married in 1429 Caterina Crispo( born 1415, date of death unknown), daughter of Nicholas Crispo, Lord of Syros, and wife Valenza- Eudokia Komnena, and sister of Francesco II, sixteenth Duke of the Archipelago.
Francis Martin Drexel
Francis Martin Drexel( April 7, 1792 – June 5, 1863) was a Philadelphia banker and artist.
He was the father of Anthony Joseph Drexel, the founder of Drexel University and the grandfather of Saint Katherine Drexel.

Question: Who is Anthony Crispo, Lord Of Syros's paternal grandfather?
Answer: Francesco I Crispo