Hubba bint Hulail
Hubba bint Hulail was the grandmother of Hashim ibn' Abd Manaf, thus the great- great- great- grandmother of the Islamic" Nabī"( Prophet) Muhammad ibn Abdullah.
Tjuyu
Tjuyu( sometimes transliterated as Thuya or Thuyu) was an Egyptian noblewoman and the mother of queen Tiye, and the wife of Yuya.
She is the grandmother of Akhenaten, and great grandmother of Tutankhamun.
Hannah Arnold
Hannah Arnold, also known as Hannah Waterman King, was the grandmother of Benedict Arnolds children.
Kaoru Hatoyama
After the elections of 2009, she became more widely known as the grandmother of Prime Minister Yukio Hatoyama and his politician brother Kunio Hatoyama.
Peter II of Portugal
"Dom" Pedro II (Peter II; 26 April 1648 – 9 December 1706), nicknamed "the Pacific", was the King of Portugal from 1683 until his death, previously serving as regent for his brother Afonso VI from 1668 until his own accession.
He was the fifth and last child of John IV and Luisa de Guzmán.
Gülbahar Hatun (wife of Mehmed II)
Gülbahar Hatun( 1432 – 1492) was the consort of Sultan Mehmed II, and mother of Sultan Bayezid II of the Ottoman Empire and the grandmother of Selim I.
Francisco António, Prince of Beira
D. Francisco Antonio of Braganza, Prince of Beira( 21 March 1795 – 11 June 1801) was the first son of D. João Maria and D. Carlota Joaquina, the Prince and Princess of Brazil.
The Prince was born on 21 March 1795, and was titled the Prince of Beira and the Duke of Barcelos, as heir- apparent to the heir- apparent of the throne of Portugal.
Antonio Francisco died on 11 June 1801, at the age of six, passing his title as" Prince of Beira" to his younger brother, the Infante D. Pedro de Alcântara.
Mona Hopton Bell
Mona Hopton Bell( 1867- 1940) was a British artist, best known for her portraits of civic figures.
She was the grandmother of the painter Jean H. Bell.
Anne Denman
Anne Denman( 1587–1661) was born in Olde Hall, Retford, Nottinghamshire.
Through a fortunate second marriage with Thomas Aylesbury, she became the grandmother of Lady Anne Hyde, Duchess of York and great- grandmother of Queen Mary II and Queen Anne.
Isabel Luísa, Princess of Beira
Infanta Isabel Luísa of Portugal (6 January 1669 – 21 October 1690) was a Portuguese "infanta" and the sole daughter of Peter II of Portugal and his first wife and former sister-in-law Maria Francisca of Savoy.
She was the heir presumptive to the throne of Portugal between 1668 and 1689, when her half-brother John was born.
As such, she was styled Princess of Beira.

Question: Who is the paternal grandmother of Isabel Luísa, Princess Of Beira?
Answer: Luisa de Guzmán