Sodium metabisulfite is added to the tissue sample to diagnose this disease, which is caused by a single substitution of valine for glutamic acid.
Sodium metabisulfite is added to the tissue sample to diagnose this disease, which is caused by a single substitution of valine for glutamic acid. Hydroxyurea [hi-DROK-see-yoo-ree-uh] can treat this disease by inducing production of the fetal form of hemoglobin, which if left untreated can cause the spleen to simultaneously enlarge and deteriorate. Heterozygote advantage may explain the prevalence of this disease in malaria-stricken regions like sub-Saharan Africa. Often triggered by low oxygen concentration, name this hereditary disease in which small blood vessels may be blocked by the characteristic crescent-shaped red blood cells.
Sodium metabisulfite is added to the tissue sample to diagnose this disease, which is caused by a single substitution of valine for glutamic acid.
sickle-cell anemia [or sickle-cell disease]