Along with cholestasis and growth retardation, overabundance of this substance is characteristic ofGRACILE syndrome.
Along with cholestasis and growth retardation, overabundance of this substance is characteristic ofGRACILE syndrome. One syndrome in which this substance is inappropriately absorbed is treated withdeferoxamine. Mutations in HFE or hepcidin cause an overload of this element, resulting in diabetes andcirrhosis. This element binds to the DMT1 transporter in the gut, and regulates gene expression by bindingto its namesake response element, which is found in the tail of TF mRNA. This element is found alongsidesulfur in a certain cluster in aconitase, and this metal is also found in a protein that contains a glutamic acidto valine mutation in sickle cell anemia patients. For 10 points, name this metal, which is found in theoxygen-binding site of hemoglobin.
Along with cholestasis and growth retardation, overabundance of this substance is characteristic ofGRACILE syndrome.
Iron