This process is inhibited by decitabine and by azacitidine at low doses, and it is detected by bisulfite treatment.
This process is inhibited by decitabine and by azacitidine at low doses, and it is detected by bisulfite treatment. It occurs heavily in Alu, LINE, and satellite repeat elements. This modification is used to distinguish the template in mismatch repair. This modification occurs at CpG islands. Its occurrence on the long arm of chromosome 15 is a classic instance of genomic imprinting, and deletion of that region results in PraderÂ–Willi or Angelman syndrome. It occurs extensively in Barr bodies, and along with histone (*) modification it is a primary mechanism of epigenetic inheritance. It usually occurs at cytosine residues to silence genes. For 10 points, name this chemical modification of DNA that involves adding a CH3 group.
This process is inhibited by decitabine and by azacitidine at low doses, and it is detected by bisulfite treatment.
DNA methylation [do NOT accept "histone methylation" or "protein methylation"]