The first signs are usually weakness in the hands, and rapid twitching in the lower legs.
The first signs are usually weakness in the hands, and rapid twitching in the lower legs. In 1993, researchers located the gene that causes this disease, first described by neurologist [*] Jean Charcot [shar-KOT] in 1874.  Muscles lose their nerve supply, causing them to atrophy, rapidly causing paralysis and death. For 10  points—Stephen Hawking suffers from what disease commonly called Lou Gehrig's disease?
The first signs are usually weakness in the hands, and rapid twitching in the lower legs.
ALS or Amyotrophic Lateral Sclerosis [accept Lou Gehrig’s disease on early buzz]