George Briggs and John Haldane showed that its pre-equilibrium step is unnecessary and instead applied steady-state approximation to calculate its constant as the sum of the backward rate and catalytic constants divided by the forward rate constant.
George Briggs and John Haldane showed that its pre-equilibrium step is unnecessary and instead applied steady-state approximation to calculate its constant as the sum of the backward rate and catalytic constants divided by the forward rate constant. Based on Victor Henri's work, its constant is equal to the dissociation constant when the turnover number is small, and also equal to the concentration at which the rate is equal to half the maximum rate. Reciprocal of the Lineweaver-Burk equation, FTP name this equation of enzyme kinetics named for German and Canadian chemists.
George Briggs and John Haldane showed that its pre-equilibrium step is unnecessary and instead applied steady-state approximation to calculate its constant as the sum of the backward rate and catalytic constants divided by the forward rate constant.
{Michaelis-Menten }equation or kinetics