Scott Denmark showed that a reagent used in this reaction can be improved by with the substitution of chlorine, while replacing that reagent with a samarium-based reagent results in higher exo/endo diastereoselectivity.
Scott Denmark showed that a reagent used in this reaction can be improved by with the substitution of chlorine, while replacing that reagent with a samarium-based reagent results in higher exo/endo diastereoselectivity. In-situ formation of its reagent can be enhanced with ultrasonication.Wittig and others developed a variant of this reaction using diazomethane, and another modification of this reaction is named for Furukawa. When this reaction is performed on Z-substituted allylic alcohols, it proceeds with high diastereoselectivity. Charette's chiral dioxaborolane ligand is commonly used to achieve an asymmetric version of this reaction. This reaction's namesake reagent consists of diiodomethane with either diethyl zinc or a zinc-copper couple. For 10 points, name this doubly-eponymous stereospecific reaction in which a carbenoid intermediate reacts with an alkene to form a cyclopropane.
Scott Denmark showed that a reagent used in this reaction can be improved by with the substitution of chlorine, while replacing that reagent with a samarium-based reagent results in higher exo/endo diastereoselectivity.
Simmons-Smith reaction [prompt on cyclopropanation]