These cells are encouraged to proliferate by a protein that is inhibited by Blisibimod and Belimumab.
These cells are encouraged to proliferate by a protein that is inhibited by Blisibimod and Belimumab.During their development they express Bruton's tyrosine kinase and rely on the Pax5 transcription factor.The only cells of this type to depend on Notch-2 signaling are those formed in the marginal zone of thespleen. Since naive mature ones only produce IgM and IgD, they must undergo class switching in order toproduce other immunoglobulins. One class of these cells has abundant rough endoplasmic reticulum andare formed in the bone marrow before becoming the "plasma" type. Following primary infection, thememory type is formed as well. For 10 points, name these lymphocytes involved in the humoral response,in contrast with T cells.
These cells are encouraged to proliferate by a protein that is inhibited by Blisibimod and Belimumab.
B cells [or B lymphocytes; prompt on lymphocytes; prompt on white blood cells]