This process can be detected using nick-end labeling in the TUNEL assay.
This process can be detected using nick-end labeling in the TUNEL assay. During this process, phosÂ•phaÂ•tidylÂ•serine becomes exposed to the cell surface and "laddering" is observed. It is triggered by BAK and BAX, and opposed by Bcl-2. Initiated by the binding of a Fas ligand, which activates caspases, it is triggered by p53 if DNA is damaged beyond repair. During this process, the cell membrane blebs, DNA breaks down, and the nucleus becomes fragmented. In the human body, its failure results in conjoined fingers or toes. For 10 points, name this biological process of programmed cell death.
This process can be detected using nick-end labeling in the TUNEL assay.
apoptosis ("a-puh-to-sis") [prompt on "programmed cell death" before it is mentioned] 