The goal of this reaction is similar to the Tebbe and Peterson Reactions, and like the Julia Reaction, it can produce an E-isomer of the desired product.
The goal of this reaction is similar to the Tebbe and Peterson Reactions, and like the Julia Reaction, it can produce an E-isomer of the desired product. It likewise shares much in common with the HWE Reaction, and the introduction of phenyllithium and then hydrochloric acid to an erythro intermediate is known as the Schlosser modification of this reaction. That dipolar intermediate is known as a betaine, which aids the olefination process, and a namesake reagent is prepared using a strong base in suspension, often in diethyl ether, and commonly couples with an aldehyde. FTP, name this reaction in which an alkene is formed from an aldehyde or ketone by combining it with a phosphonium ylide [ILL-ide], named for a German chemist.
The goal of this reaction is similar to the Tebbe and Peterson Reactions, and like the Julia Reaction, it can produce an E-isomer of the desired product.
{Wittig} Reaction