Modifications of this reaction include the Huang-Minlon Modification.
Modifications of this reaction include the Huang-Minlon Modification. The central step in this mechanism was modeled on the equally similar formation of an oxime with a carbonyl. It gives yields of about 70% due to the isomerization of side products, and has an acid analog known as the Clemmenson reaction. The key ingredients are the base and heated hydrazine hydrate. FTP, identify this reaction that creates methyl or methylene groups from carbonyl compounds, a reduction named for its two discoverers.
Modifications of this reaction include the Huang-Minlon Modification.
{Wolf-Kishner} reduction