This disease is associated with abnormalities in the SORL1 gene and the presenilin 1 and 2 genes.
This disease is associated with abnormalities in the SORL1 gene and the presenilin 1 and 2 genes. It is also strongly linked to the APOE4 allele. One hypothesis states that this disease is caused by mutations on the APP gene. Another hypothesis states that this disease is caused by abnormalities in a protein that helps to stabilize microtubules, the (*) tau protein, eventually leading to the formation of neurofibrillary tangles. This disease leads to the formation of beta-amyloid plaques. One treatment for this disease is Donepezil which increases acetylcholine production. For 10 points, identify this most common form of dementia, a disease named for a German.
This disease is associated with abnormalities in the SORL1 gene and the presenilin 1 and 2 genes.
{Alzheimer’s} disease