As part of the process of affinity maturation, the genes that code for these proteins undergo somatic hypermutation.
As part of the process of affinity maturation, the genes that code for these proteins undergo somatic hypermutation. One molecule of this type, called Rho(D), is injected before childbirth to desensitize an Rh-negative mother to her Rh-positive fetus. In a Western blot, "secondary" varieties of these molecules are linked to a horseradish peroxidase and bind to the Fc or F(ab) region of another protein of this type. By fusing myelomatous cells with spleen cells, monoclonal varieties of these epitope-binding proteins can be formed. For 10 points, name these Y-shaped glycoproteins produced by B cells that bind to foreign antigens and trigger an immune response. 
As part of the process of affinity maturation, the genes that code for these proteins undergo somatic hypermutation.
antibodies [or antibody; or immunoglobulins; or Ig; prompt on "Ab"] 