These organelles are the target location of structures whose formation is mediated by P13K. They malfunction in Niemann-Pick disease, and swelling of the liver and spleen may result from a deficiency of LAL, an enzyme that hydrolyses cholesterol esters in these organelles.
These organelles are the target location of structures whose formation is mediated by P13K. They malfunction in Niemann-Pick disease, and swelling of the liver and spleen may result from a deficiency of LAL, an enzyme that hydrolyses cholesterol esters in these organelles. One disease of these organelles results in the accumulation of gangliosides. Mannose-6-phosphate targets proteins to these organelles, which may malfunction in Tay-Sachs disease and are the site of autophagy. They use proton pumps to maintain an internal pH of 4.8 and contain lipases and hydrolases. For 10 points, name these digestive organelles that break down cell components.
These organelles are the target location of structures whose formation is mediated by P13K. They malfunction in Niemann-Pick disease, and swelling of the liver and spleen may result from a deficiency of LAL, an enzyme that hydrolyses cholesterol esters in these organelles.
lysosomes