sentence1: We found no obvious effect of LATS2-depletion on the Aurora-A kinase activity when monitored by phosphorylation state of Thr288 on Aurora-A [18] (Fig. S2), suggesting that LATS2 may be a downstream of Aurora-A as mentioned in a previous report [8]
sentence2: Among them, miR-143, miR-145 and miR-34a have been shown to inhibit cell proliferation, and miR-146a and miR-21 to increase cell growth