pwc-archive/papers-with-abstracts huggingface dataset:
Unsupervised Learning for Class Distribution Mismatch
Authors: Pan Du, Wangbo Zhao, Xinai Lu, Nian Liu, Zhikai Li, Chaoyu Gong, Suyun Zhao, Hong Chen, Cuiping Li, Kai Wang, Yang You
Date: 2025-05-11 00:00:00

Class distribution mismatch (CDM) refers to the discrepancy between class distributions in training data and target tasks. Previous methods address this by designing classifiers to categorize classes known during training, while grouping unknown or new classes into an "other" category. However, they focus on semi-supervised scenarios and heavily rely on labeled data, limiting their applicability and performance. To address this, we propose Unsupervised Learning for Class Distribution Mismatch (UCDM), which constructs positive-negative pairs from unlabeled data for classifier training. Our approach randomly samples images and uses a diffusion model to add or erase semantic classes, synthesizing diverse training pairs. Additionally, we introduce a confidence-based labeling mechanism that iteratively assigns pseudo-labels to valuable real-world data and incorporates them into the training process. Extensive experiments on three datasets demonstrate UCDM's superiority over previous semi-supervised methods. Specifically, with a 60% mismatch proportion on Tiny-ImageNet dataset, our approach, without relying on labeled data, surpasses OpenMatch (with 40 labels per class) by 35.1%, 63.7%, and 72.5% in classifying known, unknown, and new classes.
Transformer-Based Dual-Optical Attention Fusion Crowd Head Point Counting and Localization Network
Authors: Fei Zhou, Yi Li, Mingqing Zhu
Date: 2025-05-11 00:00:00
Tasks: Crowd Counting, Data Augmentation

In this paper, the dual-optical attention fusion crowd head point counting model (TAPNet) is proposed to address the problem of the difficulty of accurate counting in complex scenes such as crowd dense occlusion and low light in crowd counting tasks under UAV view. The model designs a dual-optical attention fusion module (DAFP) by introducing complementary information from infrared images to improve the accuracy and robustness of all-day crowd counting. In order to fully utilize different modal information and solve the problem of inaccurate localization caused by systematic misalignment between image pairs, this paper also proposes an adaptive two-optical feature decomposition fusion module (AFDF). In addition, we optimize the training strategy to improve the model robustness through spatial random offset data augmentation. Experiments on two challenging public datasets, DroneRGBT and GAIIC2, show that the proposed method outperforms existing techniques in terms of performance, especially in challenging dense low-light scenes. Code is available at https://github.com/zz-zik/TAPNet
Whitened CLIP as a Likelihood Surrogate of Images and Captions
Authors: Roy Betser, Meir Yossef Levi, Guy Gilboa
Date: 2025-05-11 00:00:00

Likelihood approximations for images are not trivial to compute and can be useful in many applications. We examine the use of Contrastive Language-Image Pre-training (CLIP) to assess the likelihood of images and captions. We introduce \textit{Whitened CLIP}, a novel transformation of the CLIP latent space via an invertible linear operation. This transformation ensures that each feature in the embedding space has zero mean, unit standard deviation, and no correlation with all other features, resulting in an identity covariance matrix. We show that the whitened embeddings statistics can be well approximated as a standard normal distribution, thus, the log-likelihood is estimated simply by the square Euclidean norm in the whitened embedding space. The whitening procedure is completely training-free and performed using a pre-computed whitening matrix, hence, is very fast. We present several preliminary experiments demonstrating the properties and applicability of these likelihood scores to images and captions.
Bi-directional Self-Registration for Misaligned Infrared-Visible Image Fusion
Authors: Timing Li, Bing Cao, Pengfei Zhu, Bin Xiao, QinGhua Hu
Date: 2025-05-11 00:00:00
Tasks: Image Registration

Acquiring accurately aligned multi-modal image pairs is fundamental for achieving high-quality multi-modal image fusion. To address the lack of ground truth in current multi-modal image registration and fusion methods, we propose a novel self-supervised \textbf{B}i-directional \textbf{S}elf-\textbf{R}egistration framework (\textbf{B-SR}). Specifically, B-SR utilizes a proxy data generator (PDG) and an inverse proxy data generator (IPDG) to achieve self-supervised global-local registration. Visible-infrared image pairs with spatially misaligned differences are aligned to obtain global differences through the registration module. The same image pairs are processed by PDG, such as cropping, flipping, stitching, etc., and then aligned to obtain local differences. IPDG converts the obtained local differences into pseudo-global differences, which are used to perform global-local difference consistency with the global differences. Furthermore, aiming at eliminating the effect of modal gaps on the registration module, we design a neighborhood dynamic alignment loss to achieve cross-modal image edge alignment. Extensive experiments on misaligned multi-modal images demonstrate the effectiveness of the proposed method in multi-modal image alignment and fusion against the competing methods. Our code will be publicly available.
Uni-AIMS: AI-Powered Microscopy Image Analysis
Authors: Yanhui Hong, Nan Wang, Zhiyi Xia, Haoyi Tao, Xi Fang, Yiming Li, Jiankun Wang, Peng Jin, Xiaochen Cai, Shengyu Li, Ziqi Chen, Zezhong Zhang, Guolin Ke, Linfeng Zhang
Date: 2025-05-11 00:00:00
Tasks: Synthetic Data Generation

This paper presents a systematic solution for the intelligent recognition and automatic analysis of microscopy images. We developed a data engine that generates high-quality annotated datasets through a combination of the collection of diverse microscopy images from experiments, synthetic data generation and a human-in-the-loop annotation process. To address the unique challenges of microscopy images, we propose a segmentation model capable of robustly detecting both small and large objects. The model effectively identifies and separates thousands of closely situated targets, even in cluttered visual environments. Furthermore, our solution supports the precise automatic recognition of image scale bars, an essential feature in quantitative microscopic analysis. Building upon these components, we have constructed a comprehensive intelligent analysis platform and validated its effectiveness and practicality in real-world applications. This study not only advances automatic recognition in microscopy imaging but also ensures scalability and generalizability across multiple application domains, offering a powerful tool for automated microscopic analysis in interdisciplinary research.
Building a Human-Verified Clinical Reasoning Dataset via a Human LLM Hybrid Pipeline for Trustworthy Medical AI
Authors: Chao Ding, Mouxiao Bian, Pengcheng Chen, Hongliang Zhang, Tianbin Li, Lihao Liu, Jiayuan Chen, Zhuoran Li, Yabei Zhong, Yongqi Liu, Haiqing Huang, Dongming Shan, Junjun He, Jie Xu
Date: 2025-05-11 00:00:00
Tasks: Medical Question Answering, Question Answering

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the predominant reliance of current medical LLMs on corpora from scientific literature or synthetic data, which often lack the granular expert validation and high clinical relevance essential for advancing their specialized medical capabilities. To address these critical gaps, we introduce a highly clinically relevant dataset with 31,247 medical question-answer pairs, each accompanied by expert-validated chain-of-thought (CoT) explanations. This resource, spanning multiple clinical domains, was curated via a scalable human-LLM hybrid pipeline: LLM-generated rationales were iteratively reviewed, scored, and refined by medical experts against a structured rubric, with substandard outputs revised through human effort or guided LLM regeneration until expert consensus. This publicly available dataset provides a vital source for the development of medical LLMs that capable of transparent and verifiable reasoning, thereby advancing safer and more interpretable AI in medicine.
Enhancing Monocular Height Estimation via Sparse LiDAR-Guided Correction
Authors: Jian Song, Hongruixuan Chen, Naoto Yokoya
Date: 2025-05-11 00:00:00
Tasks: Domain Adaptation

Monocular height estimation (MHE) from very-high-resolution (VHR) remote sensing imagery via deep learning is notoriously challenging due to the lack of sufficient structural information. Conventional digital elevation models (DEMs), typically derived from airborne LiDAR or multi-view stereo, remain costly and geographically limited. Recently, models trained on synthetic data and refined through domain adaptation have shown remarkable performance in MHE, yet it remains unclear how these models make predictions or how reliable they truly are. In this paper, we investigate a state-of-the-art MHE model trained purely on synthetic data to explore where the model looks when making height predictions. Through systematic analyses, we find that the model relies heavily on shadow cues, a factor that can lead to overestimation or underestimation of heights when shadows deviate from expected norms. Furthermore, the inherent difficulty of evaluating regression tasks with the human eye underscores additional limitations of purely synthetic training. To address these issues, we propose a novel correction pipeline that integrates sparse, imperfect global LiDAR measurements (ICESat-2) with deep-learning outputs to improve local accuracy and achieve spatially consistent corrections. Our method comprises two stages: pre-processing raw ICESat-2 data, followed by a random forest-based approach to densely refine height estimates. Experiments in three representative urban regions -- Saint-Omer, Tokyo, and Sao Paulo -- reveal substantial error reductions, with mean absolute error (MAE) decreased by 22.8\%, 6.9\%, and 4.9\%, respectively. These findings highlight the critical role of shadow awareness in synthetic data-driven models and demonstrate how fusing imperfect real-world LiDAR data can bolster the robustness of MHE, paving the way for more reliable and scalable 3D mapping solutions.
CheXLearner: Text-Guided Fine-Grained Representation Learning for Progression Detection
Authors: Yuanzhuo Wang, Junwen Duan, Xinyu Li, Jianxin Wang
Date: 2025-05-11 00:00:00
Tasks: Decision Making, Medical Image Analysis, Representation Learning

Temporal medical image analysis is essential for clinical decision-making, yet existing methods either align images and text at a coarse level - causing potential semantic mismatches - or depend solely on visual information, lacking medical semantic integration. We present CheXLearner, the first end-to-end framework that unifies anatomical region detection, Riemannian manifold-based structure alignment, and fine-grained regional semantic guidance. Our proposed Med-Manifold Alignment Module (Med-MAM) leverages hyperbolic geometry to robustly align anatomical structures and capture pathologically meaningful discrepancies across temporal chest X-rays. By introducing regional progression descriptions as supervision, CheXLearner achieves enhanced cross-modal representation learning and supports dynamic low-level feature optimization. Experiments show that CheXLearner achieves 81.12% (+17.2%) average accuracy and 80.32% (+11.05%) F1-score on anatomical region progression detection - substantially outperforming state-of-the-art baselines, especially in structurally complex regions. Additionally, our model attains a 91.52% average AUC score in downstream disease classification, validating its superior feature representation.
Multi-Modal Explainable Medical AI Assistant for Trustworthy Human-AI Collaboration
Authors: Honglong Yang, Shanshan Song, Yi Qin, Lehan Wang, Haonan Wang, Xinpeng Ding, Qixiang Zhang, Bodong Du, Xiaomeng Li
Date: 2025-05-11 00:00:00
Tasks: Benchmarking, Descriptive, Diagnostic, Question Answering, Uncertainty Quantification, Visual Question Answering

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities. Here, we present XMedGPT, a clinician-centric, multi-modal AI assistant that integrates textual and visual interpretability to support transparent and trustworthy medical decision-making. XMedGPT not only produces accurate diagnostic and descriptive outputs, but also grounds referenced anatomical sites within medical images, bridging critical gaps in interpretability and enhancing clinician usability. To support real-world deployment, we introduce a reliability indexing mechanism that quantifies uncertainty through consistency-based assessment via interactive question-answering. We validate XMedGPT across four pillars: multi-modal interpretability, uncertainty quantification, and prognostic modeling, and rigorous benchmarking. The model achieves an IoU of 0.703 across 141 anatomical regions, and a Kendall's tau-b of 0.479, demonstrating strong alignment between visual rationales and clinical outcomes. For uncertainty estimation, it attains an AUC of 0.862 on visual question answering and 0.764 on radiology report generation. In survival and recurrence prediction for lung and glioma cancers, it surpasses prior leading models by 26.9%, and outperforms GPT-4o by 25.0%. Rigorous benchmarking across 347 datasets covers 40 imaging modalities and external validation spans 4 anatomical systems confirming exceptional generalizability, with performance gains surpassing existing GMAI by 20.7% for in-domain evaluation and 16.7% on 11,530 in-house data evaluation. Together, XMedGPT represents a significant leap forward in clinician-centric AI integration, offering trustworthy and scalable support for diverse healthcare applications.
Image Classification Using a Diffusion Model as a Pre-Training Model
Authors: Kosuke Ukita, Ye Xiaolong, Tsuyoshi Okita
Date: 2025-05-11 00:00:00
Tasks: Contrastive Learning, image-classification, Image Classification, model, Self-Supervised Learning, zero-shot-classification, Zero-Shot Learning

In this paper, we propose a diffusion model that integrates a representation-conditioning mechanism, where the representations derived from a Vision Transformer (ViT) are used to condition the internal process of a Transformer-based diffusion model. This approach enables representation-conditioned data generation, addressing the challenge of requiring large-scale labeled datasets by leveraging self-supervised learning on unlabeled data. We evaluate our method through a zero-shot classification task for hematoma detection in brain imaging. Compared to the strong contrastive learning baseline, DINOv2, our method achieves a notable improvement of +6.15% in accuracy and +13.60% in F1-score, demonstrating its effectiveness in image classification.
Joint Low-level and High-level Textual Representation Learning with Multiple Masking Strategies
Authors: Zhengmi Tang, Yuto Mitsui, Tomo Miyazaki, Shinichiro Omachi
Date: 2025-05-11 00:00:00
Tasks: Contrastive Learning, Image Super-Resolution, Representation Learning, Self-Supervised Learning, Super-Resolution

Most existing text recognition methods are trained on large-scale synthetic datasets due to the scarcity of labeled real-world datasets. Synthetic images, however, cannot faithfully reproduce real-world scenarios, such as uneven illumination, irregular layout, occlusion, and degradation, resulting in performance disparities when handling complex real-world images. Recent self-supervised learning techniques, notably contrastive learning and masked image modeling (MIM), narrow this domain gap by exploiting unlabeled real text images. This study first analyzes the original Masked AutoEncoder (MAE) and observes that random patch masking predominantly captures low-level textural features but misses high-level contextual representations. To fully exploit the high-level contextual representations, we introduce random blockwise and span masking in the text recognition task. These strategies can mask the continuous image patches and completely remove some characters, forcing the model to infer relationships among characters within a word. Our Multi-Masking Strategy (MMS) integrates random patch, blockwise, and span masking into the MIM frame, which jointly learns low and high-level textual representations. After fine-tuning with real data, MMS outperforms the state-of-the-art self-supervised methods in various text-related tasks, including text recognition, segmentation, and text-image super-resolution.
Predicting Surgical Safety Margins in Osteosarcoma Knee Resections: An Unsupervised Approach
Authors: Carolina Vargas-Ecos, Edwin Salcedo
Date: 2025-05-11 00:00:00

According to the Pan American Health Organization, the number of cancer cases in Latin America was estimated at 4.2 million in 2022 and is projected to rise to 6.7 million by 2045. Osteosarcoma, one of the most common and deadly bone cancers affecting young people, is difficult to detect due to its unique texture and intensity. Surgical removal of osteosarcoma requires precise safety margins to ensure complete resection while preserving healthy tissue. Therefore, this study proposes a method for estimating the confidence interval of surgical safety margins in osteosarcoma surgery around the knee. The proposed approach uses MRI and X-ray data from open-source repositories, digital processing techniques, and unsupervised learning algorithms (such as k-means clustering) to define tumor boundaries. Experimental results highlight the potential for automated, patient-specific determination of safety margins.
Visual Instruction Tuning with Chain of Region-of-Interest
Authors: Yixin Chen, Shuai Zhang, Boran Han, Bernie Wang
Date: 2025-05-11 00:00:00
Tasks: MME

High-resolution (HR) images are pivotal for enhancing the recognition and understanding capabilities of multimodal large language models (MLLMs). However, directly increasing image resolution can significantly escalate computational demands. In this study, we propose a method called Chain of Region-of-Interest (CoRoI) for Visual Instruction Tuning, aimed at alleviating the computational burden associated with high-resolution images for MLLMs. Drawing inspiration from the selective nature of the human visual system, we recognize that not all regions within high-resolution images carry equal importance. CoRoI seeks to identify and prioritize the most informative regions, thereby enhancing multimodal visual comprehension and recognition while circumventing the need for processing lengthy HR image tokens. Through extensive experiments on 11 benchmarks, we validate the efficacy of CoRoI across varying sizes, ranging from 7B to 34B in parameters. Our models consistently demonstrate superior performance across diverse multimodal benchmarks and tasks. Notably, our method outperforms LLaVA-NeXT on almost all benchmarks and our finetuned 34B model surpasses proprietary methods like Gemini Pro 1.0 on six benchmarks, as well as outperforming GPT-4V on MMB, SEED-I, and MME.
Fine-Grained Bias Exploration and Mitigation for Group-Robust Classification
Authors: Miaoyun Zhao, Qiang Zhang, Chenrong Li
Date: 2025-05-11 00:00:00
Tasks: Binary Classification, Robust classification

Achieving group-robust generalization in the presence of spurious correlations remains a significant challenge, particularly when bias annotations are unavailable. Recent studies on Class-Conditional Distribution Balancing (CCDB) reveal that spurious correlations often stem from mismatches between the class-conditional and marginal distributions of bias attributes. They achieve promising results by addressing this issue through simple distribution matching in a bias-agnostic manner. However, CCDB approximates each distribution using a single Gaussian, which is overly simplistic and rarely holds in real-world applications. To address this limitation, we propose a novel method called Bias Exploration via Overfitting (BEO), which captures each distribution in greater detail by modeling it as a mixture of latent groups. Building on these group-level descriptions, we introduce a fine-grained variant of CCDB, termed FG-CCDB, which performs more precise distribution matching and balancing within each group. Through group-level reweighting, FG-CCDB learns sample weights from a global perspective, achieving stronger mitigation of spurious correlations without incurring substantial storage or computational costs. Extensive experiments demonstrate that BEO serves as a strong proxy for ground-truth bias annotations and can be seamlessly integrated with bias-supervised methods. Moreover, when combined with FG-CCDB, our method performs on par with bias-supervised approaches on binary classification tasks and significantly outperforms them in highly biased multi-class scenarios.
Active Learning for Multi-class Image Classification
Authors: Thien Nhan Vo
Date: 2025-05-11 00:00:00
Tasks: Active Learning, Binary Classification, Classification, image-classification, Image Classification

A principle bottleneck in image classification is the large number of training examples needed to train a classifier. Using active learning, we can reduce the number of training examples to teach a CNN classifier by strategically selecting examples. Assigning values to image examples using different uncertainty metrics allows the model to identify and select high-value examples in a smaller training set size. We demonstrate results for digit recognition and fruit classification on the MNIST and Fruits360 data sets. We formally compare results for four different uncertainty metrics. Finally, we observe active learning is also effective on simpler (binary) classification tasks, but marked improvement from random sampling is more evident on more difficult tasks. We show active learning is a viable algorithm for image classification problems.
Missing Data Estimation for MR Spectroscopic Imaging via Mask-Free Deep Learning Methods
Authors: Tan-Hanh Pham, Ovidiu C. Andronesi, Xianqi Li, Kim-Doang Nguyen
Date: 2025-05-11 00:00:00
Tasks: SSIM

Magnetic Resonance Spectroscopic Imaging (MRSI) is a powerful tool for non-invasive mapping of brain metabolites, providing critical insights into neurological conditions. However, its utility is often limited by missing or corrupted data due to motion artifacts, magnetic field inhomogeneities, or failed spectral fitting-especially in high resolution 3D acquisitions. To address this, we propose the first deep learning-based, mask-free framework for estimating missing data in MRSI metabolic maps. Unlike conventional restoration methods that rely on explicit masks to identify missing regions, our approach implicitly detects and estimates these areas using contextual spatial features through 2D and 3D U-Net architectures. We also introduce a progressive training strategy to enhance robustness under varying levels of data degradation. Our method is evaluated on both simulated and real patient datasets and consistently outperforms traditional interpolation techniques such as cubic and linear interpolation. The 2D model achieves an MSE of 0.002 and an SSIM of 0.97 with 20% missing voxels, while the 3D model reaches an MSE of 0.001 and an SSIM of 0.98 with 15% missing voxels. Qualitative results show improved fidelity in estimating missing data, particularly in metabolically heterogeneous regions and ventricular regions. Importantly, our model generalizes well to real-world datasets without requiring retraining or mask input. These findings demonstrate the effectiveness and broad applicability of mask-free deep learning for MRSI restoration, with strong potential for clinical and research integration.