pwc-archive/papers-with-abstracts huggingface dataset:
Cross-Document Cross-Lingual NLI via RST-Enhanced Graph Fusion and Interpretability Prediction
Authors: Mengying Yuan, Wenhao Wang, Zixuan Wang, Yujie Huang, Kangli Wei, Fei Li, Chong Teng, Donghong Ji
Date: 2025-04-11 00:00:00
Tasks: Cross-Lingual Natural Language Inference, Graph Attention, Hallucination, Information Retrieval, Natural Language Inference, Retrieval, Semantic Retrieval

Natural Language Inference (NLI) is a fundamental task in natural language processing. While NLI has developed many sub-directions such as sentence-level NLI, document-level NLI and cross-lingual NLI, Cross-Document Cross-Lingual NLI (CDCL-NLI) remains largely unexplored. In this paper, we propose a novel paradigm: CDCL-NLI, which extends traditional NLI capabilities to multi-document, multilingual scenarios. To support this task, we construct a high-quality CDCL-NLI dataset including 25,410 instances and spanning 26 languages. To address the limitations of previous methods on CDCL-NLI task, we further propose an innovative method that integrates RST-enhanced graph fusion with interpretability-aware prediction. Our approach leverages RST (Rhetorical Structure Theory) within heterogeneous graph neural networks for cross-document context modeling, and employs a structure-aware semantic alignment based on lexical chains for cross-lingual understanding. For NLI interpretability, we develop an EDU (Elementary Discourse Unit)-level attribution framework that produces extractive explanations. Extensive experiments demonstrate our approach's superior performance, achieving significant improvements over both conventional NLI models as well as large language models. Our work sheds light on the study of NLI and will bring research interest on cross-document cross-lingual context understanding, hallucination elimination and interpretability inference. Our code and datasets are available at \href{https://anonymous.4open.science/r/CDCL-NLI-637E/}{CDCL-NLI-link} for peer review.
Reconstructing Sepsis Trajectories from Clinical Case Reports using LLMs: the Textual Time Series Corpus for Sepsis
Authors: Shahriar Noroozizadeh, Jeremy C. Weiss
Date: 2025-04-12 00:00:00
Tasks: Time Series

Clinical case reports and discharge summaries may be the most complete and accurate summarization of patient encounters, yet they are finalized, i.e., timestamped after the encounter. Complementary data structured streams become available sooner but suffer from incompleteness. To train models and algorithms on more complete and temporally fine-grained data, we construct a pipeline to phenotype, extract, and annotate time-localized findings within case reports using large language models. We apply our pipeline to generate an open-access textual time series corpus for Sepsis-3 comprising 2,139 case reports from the Pubmed-Open Access (PMOA) Subset. To validate our system, we apply it on PMOA and timeline annotations from I2B2/MIMIC-IV and compare the results to physician-expert annotations. We show high recovery rates of clinical findings (event match rates: O1-preview--0.755, Llama 3.3 70B Instruct--0.753) and strong temporal ordering (concordance: O1-preview--0.932, Llama 3.3 70B Instruct--0.932). Our work characterizes the ability of LLMs to time-localize clinical findings in text, illustrating the limitations of LLM use for temporal reconstruction and providing several potential avenues of improvement via multimodal integration.
A Comprehensive Survey of Reward Models: Taxonomy, Applications, Challenges, and Future
Authors: Jialun Zhong, Wei Shen, Yanzeng Li, Songyang Gao, Hua Lu, Yicheng Chen, Yang Zhang, Wei Zhou, Jinjie Gu, Lei Zou
Date: 2025-04-12 00:00:00

Reward Model (RM) has demonstrated impressive potential for enhancing Large Language Models (LLM), as RM can serve as a proxy for human preferences, providing signals to guide LLMs' behavior in various tasks. In this paper, we provide a comprehensive overview of relevant research, exploring RMs from the perspectives of preference collection, reward modeling, and usage. Next, we introduce the applications of RMs and discuss the benchmarks for evaluation. Furthermore, we conduct an in-depth analysis of the challenges existing in the field and dive into the potential research directions. This paper is dedicated to providing beginners with a comprehensive introduction to RMs and facilitating future studies. The resources are publicly available at github\footnote{https://github.com/JLZhong23/awesome-reward-models}.
Speculative Thinking: Enhancing Small-Model Reasoning with Large Model Guidance at Inference Time
Authors: Wang Yang, Xiang Yue, Vipin Chaudhary, Xiaotian Han
Date: 2025-04-12 00:00:00
Tasks: model

Recent advances leverage post-training to enhance model reasoning performance, which typically requires costly training pipelines and still suffers from inefficient, overly lengthy outputs. We introduce Speculative Thinking, a training-free framework that enables large reasoning models to guide smaller ones during inference at the reasoning level, distinct from speculative decoding, which operates at the token level. Our approach is based on two observations: (1) reasoning-supportive tokens such as "wait" frequently appear after structural delimiters like "\n\n", serving as signals for reflection or continuation; and (2) larger models exhibit stronger control over reflective behavior, reducing unnecessary backtracking while improving reasoning quality. By strategically delegating reflective steps to a more capable model, our method significantly boosts the reasoning accuracy of reasoning models while shortening their output. With the assistance of the 32B reasoning model, the 1.5B model's accuracy on MATH500 increases from 83.2% to 89.4%, marking a substantial improvement of 6.2%. Simultaneously, the average output length is reduced from 5439 tokens to 4583 tokens, representing a 15.7% decrease. Moreover, when applied to a non-reasoning model (Qwen-2.5-7B-Instruct), our framework boosts its accuracy from 74.0% to 81.8% on the same benchmark, achieving a relative improvement of 7.8%.
HM-RAG: Hierarchical Multi-Agent Multimodal Retrieval Augmented Generation
Authors: Pei Liu, Xin Liu, Ruoyu Yao, Junming Liu, Siyuan Meng, Ding Wang, Jun Ma
Date: 2025-04-13 00:00:00
Tasks: Multimodal Reasoning, RAG, Retrieval, Retrieval-augmented Generation

While Retrieval-Augmented Generation (RAG) augments Large Language Models (LLMs) with external knowledge, conventional single-agent RAG remains fundamentally limited in resolving complex queries demanding coordinated reasoning across heterogeneous data ecosystems. We present HM-RAG, a novel Hierarchical Multi-agent Multimodal RAG framework that pioneers collaborative intelligence for dynamic knowledge synthesis across structured, unstructured, and graph-based data. The framework is composed of three-tiered architecture with specialized agents: a Decomposition Agent that dissects complex queries into contextually coherent sub-tasks via semantic-aware query rewriting and schema-guided context augmentation; Multi-source Retrieval Agents that carry out parallel, modality-specific retrieval using plug-and-play modules designed for vector, graph, and web-based databases; and a Decision Agent that uses consistency voting to integrate multi-source answers and resolve discrepancies in retrieval results through Expert Model Refinement. This architecture attains comprehensive query understanding by combining textual, graph-relational, and web-derived evidence, resulting in a remarkable 12.95% improvement in answer accuracy and a 3.56% boost in question classification accuracy over baseline RAG systems on the ScienceQA and CrisisMMD benchmarks. Notably, HM-RAG establishes state-of-the-art results in zero-shot settings on both datasets. Its modular architecture ensures seamless integration of new data modalities while maintaining strict data governance, marking a significant advancement in addressing the critical challenges of multimodal reasoning and knowledge synthesis in RAG systems. Code is available at https://github.com/ocean-luna/HMRAG.
Span-level Emotion-Cause-Category Triplet Extraction with Instruction Tuning LLMs and Data Augmentation
Authors: Xiangju Li, Dong Yang, Xiaogang Zhu, Faliang Huang, Peng Zhang, Zhongying Zhao
Date: 2025-04-13 00:00:00
Tasks: Data Augmentation, Emotion-Cause Pair Extraction, Information Retrieval, Triplet

Span-level emotion-cause-category triplet extraction represents a novel and complex challenge within emotion cause analysis. This task involves identifying emotion spans, cause spans, and their associated emotion categories within the text to form structured triplets. While prior research has predominantly concentrated on clause-level emotion-cause pair extraction and span-level emotion-cause detection, these methods often confront challenges originating from redundant information retrieval and difficulty in accurately determining emotion categories, particularly when emotions are expressed implicitly or ambiguously. To overcome these challenges, this study explores a fine-grained approach to span-level emotion-cause-category triplet extraction and introduces an innovative framework that leverages instruction tuning and data augmentation techniques based on large language models. The proposed method employs task-specific triplet extraction instructions and utilizes low-rank adaptation to fine-tune large language models, eliminating the necessity for intricate task-specific architectures. Furthermore, a prompt-based data augmentation strategy is developed to address data scarcity by guiding large language models in generating high-quality synthetic training data. Extensive experimental evaluations demonstrate that the proposed approach significantly outperforms existing baseline methods, achieving at least a 12.8% improvement in span-level emotion-cause-category triplet extraction metrics. The results demonstrate the method's effectiveness and robustness, offering a promising avenue for advancing research in emotion cause analysis. The source code is available at https://github.com/zxgnlp/InstruDa-LLM.
QM-ToT: A Medical Tree of Thoughts Reasoning Framework for Quantized Model
Authors: Zongxian Yang, Jiayu Qian, Zhi-An Huang, Kay Chen Tan
Date: 2025-04-13 00:00:00

Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical terminology and the need for accurate clinical insights, leading to performance reduction when quantized for resource-constrained deployment. To address these issues, we propose Quantized Medical Tree of Thought (QM-ToT), a path-based reasoning framework. QM-ToT leverages a Tree of Thought (ToT) reasoning approach to decompose complex medical problems into manageable subtasks, coupled with evaluator assessment layers. This framework facilitates substantial performance improvements in INT4-quantized models on the challenging MedQAUSMLE dataset. Specifically, we demonstrate a remarkable accuracy increase from 34% to 50% for the LLaMA2-70b model and from 58.77% to 69.49% for LLaMA-3.1-8b. Besides, we also proposed an effect data distillation method based on ToT. Compared to the traditional distillation method, we achieved an improvement of 86. 27% while using only 3.9% of the data.This work, for the first time, showcases the potential of ToT to significantly enhance performance on complex biomedical tasks, establishing a crucial foundation for future advances in deploying high-performing quantized LLM in resource-limited medical settings.
You've Changed: Detecting Modification of Black-Box Large Language Models
Authors: Alden Dima, James Foulds, SHimei Pan, Philip Feldman
Date: 2025-04-14 00:00:00

Large Language Models (LLMs) are often provided as a service via an API, making it challenging for developers to detect changes in their behavior. We present an approach to monitor LLMs for changes by comparing the distributions of linguistic and psycholinguistic features of generated text. Our method uses a statistical test to determine whether the distributions of features from two samples of text are equivalent, allowing developers to identify when an LLM has changed. We demonstrate the effectiveness of our approach using five OpenAI completion models and Meta's Llama 3 70B chat model. Our results show that simple text features coupled with a statistical test can distinguish between language models. We also explore the use of our approach to detect prompt injection attacks. Our work enables frequent LLM change monitoring and avoids computationally expensive benchmark evaluations.
Paging Dr. GPT: Extracting Information from Clinical Notes to Enhance Patient Predictions
Authors: David Anderson, Michaela Anderson, Margret Bjarnadottir, Stephen Mahar, Shriyan Reyya
Date: 2025-04-14 00:00:00
Tasks: Mortality Prediction

There is a long history of building predictive models in healthcare using tabular data from electronic medical records. However, these models fail to extract the information found in unstructured clinical notes, which document diagnosis, treatment, progress, medications, and care plans. In this study, we investigate how answers generated by GPT-4o-mini (ChatGPT) to simple clinical questions about patients, when given access to the patient's discharge summary, can support patient-level mortality prediction. Using data from 14,011 first-time admissions to the Coronary Care or Cardiovascular Intensive Care Units in the MIMIC-IV Note dataset, we implement a transparent framework that uses GPT responses as input features in logistic regression models. Our findings demonstrate that GPT-based models alone can outperform models trained on standard tabular data, and that combining both sources of information yields even greater predictive power, increasing AUC by an average of 5.1 percentage points and increasing positive predictive value by 29.9 percent for the highest-risk decile. These results highlight the value of integrating large language models (LLMs) into clinical prediction tasks and underscore the broader potential for using LLMs in any domain where unstructured text data remains an underutilized resource.
Streamlining Biomedical Research with Specialized LLMs
Authors: Linqing Chen, Weilei Wang, Yubin Xia, Wentao Wu, Peng Xu, Zilong Bai, Jie Fang, Chaobo Xu, Ran Hu, Licong Xu, Haoran Hua, Jing Sun, Hanmeng Zhong, Jin Liu, Tian Qiu, Haowen Liu, Meng Hu, Xiuwen Li, Fei Gao, Yong Gu, Tao Shi, Chaochao Wang, Jianping Lu, Cheng Sun, Yixin Wang, Shengjie Yang, Yuancheng LI, Lu Jin, Lisha Zhang, Fu Bian, Zhongkai Ye, Lidong Pei, Changyang Tu
Date: 2025-04-15 00:00:00
Tasks: Decision Making, Dialogue Generation, Information Retrieval, Question Answering, Retrieval

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates seamless interaction among diverse components, enabling cross-validation of outputs to produce accurate, high-quality responses enriched with relevant data, images, tables, and other modalities. We demonstrate the system's capability to enhance response precision by leveraging a robust question-answering model, significantly improving the quality of dialogue generation. The system provides an accessible platform for real-time, high-fidelity interactions, allowing users to benefit from efficient human-computer interaction, precise retrieval, and simultaneous access to a wide range of literature and data. This dramatically improves the research efficiency of professionals in the biomedical and pharmaceutical domains and facilitates faster, more informed decision-making throughout the R\&D process. Furthermore, the system proposed in this paper is available at https://synapse-chat.patsnap.com.
Benchmarking Biopharmaceuticals Retrieval-Augmented Generation Evaluation
Authors: Hanmeng Zhong, Linqing Chen, Weilei Wang, Wentao Wu
Date: 2025-04-15 00:00:00
Tasks: Benchmarking, Question Answering, Retrieval, Retrieval-augmented Generation

Recently, the application of the retrieval-augmented Large Language Models (LLMs) in specific domains has gained significant attention, especially in biopharmaceuticals. However, in this context, there is no benchmark specifically designed for biopharmaceuticals to evaluate LLMs. In this paper, we introduce the Biopharmaceuticals Retrieval-Augmented Generation Evaluation (BRAGE) , the first benchmark tailored for evaluating LLMs' Query and Reference Understanding Capability (QRUC) in the biopharmaceutical domain, available in English, French, German and Chinese. In addition, Traditional Question-Answering (QA) metrics like accuracy and exact match fall short in the open-ended retrieval-augmented QA scenarios. To address this, we propose a citation-based classification method to evaluate the QRUC of LLMs to understand the relationship between queries and references. We apply this method to evaluate the mainstream LLMs on BRAGE. Experimental results show that there is a significant gap in the biopharmaceutical QRUC of mainstream LLMs, and their QRUC needs to be improved.
Propaganda via AI? A Study on Semantic Backdoors in Large Language Models
Authors: Nay Myat Min, Long H. Pham, Yige Li, Jun Sun
Date: 2025-04-15 00:00:00

Large language models (LLMs) demonstrate remarkable performance across myriad language tasks, yet they remain vulnerable to backdoor attacks, where adversaries implant hidden triggers that systematically manipulate model outputs. Traditional defenses focus on explicit token-level anomalies and therefore overlook semantic backdoors-covert triggers embedded at the conceptual level (e.g., ideological stances or cultural references) that rely on meaning-based cues rather than lexical oddities. We first show, in a controlled finetuning setting, that such semantic backdoors can be implanted with only a small poisoned corpus, establishing their practical feasibility. We then formalize the notion of semantic backdoors in LLMs and introduce a black-box detection framework, RAVEN (short for "Response Anomaly Vigilance for uncovering semantic backdoors"), which combines semantic entropy with cross-model consistency analysis. The framework probes multiple models with structured topic-perspective prompts, clusters the sampled responses via bidirectional entailment, and flags anomalously uniform outputs; cross-model comparison isolates model-specific anomalies from corpus-wide biases. Empirical evaluations across diverse LLM families (GPT-4o, Llama, DeepSeek, Mistral) uncover previously undetected semantic backdoors, providing the first proof-of-concept evidence of these hidden vulnerabilities and underscoring the urgent need for concept-level auditing of deployed language models. We open-source our code and data at https://github.com/NayMyatMin/RAVEN.
A Large-Language Model Framework for Relative Timeline Extraction from PubMed Case Reports
Authors: Jing Wang, Jeremy C Weiss
Date: 2025-04-15 00:00:00
Tasks: Language Modeling, Language Modelling, Large Language Model, Temporal Localization

Timing of clinical events is central to characterization of patient trajectories, enabling analyses such as process tracing, forecasting, and causal reasoning. However, structured electronic health records capture few data elements critical to these tasks, while clinical reports lack temporal localization of events in structured form. We present a system that transforms case reports into textual time series-structured pairs of textual events and timestamps. We contrast manual and large language model (LLM) annotations (n=320 and n=390 respectively) of ten randomly-sampled PubMed open-access (PMOA) case reports (N=152,974) and assess inter-LLM agreement (n=3,103; N=93). We find that the LLM models have moderate event recall(O1-preview: 0.80) but high temporal concordance among identified events (O1-preview: 0.95). By establishing the task, annotation, and assessment systems, and by demonstrating high concordance, this work may serve as a benchmark for leveraging the PMOA corpus for temporal analytics.
Replicating ReLM Results: Validating Large Language Models with ReLM
Authors: Reece Adamson, Erin Song
Date: 2025-04-16 00:00:00
Tasks: Memorization

Validating Large Language Models with ReLM explores the application of formal languages to evaluate and control Large Language Models (LLMs) for memorization, bias, and zero-shot performance. Current approaches for evaluating these types behavior are often slow, imprecise, costly, or introduce biases of their own, but are necessary due to the importance of this behavior when productionizing LLMs. This project reproduces key results from the original ReLM paper and expounds on the approach and applications with an emphasis on the relevance to the field of systems for machine learning.
A Method for Handling Negative Similarities in Explainable Graph Spectral Clustering of Text Documents -- Extended Version
Authors: Mieczysław A. Kłopotek, Sławomir T. Wierzchoń, Bartłomiej Starosta, Dariusz Czerski, Piotr Borkowski
Date: 2025-04-16 00:00:00

This paper investigates the problem of Graph Spectral Clustering with negative similarities, resulting from document embeddings different from the traditional Term Vector Space (like doc2vec, GloVe, etc.). Solutions for combinatorial Laplacians and normalized Laplacians are discussed. An experimental investigation shows the advantages and disadvantages of 6 different solutions proposed in the literature and in this research. The research demonstrates that GloVe embeddings frequently cause failures of normalized Laplacian based GSC due to negative similarities. Furthermore, application of methods curing similarity negativity leads to accuracy improvement for both combinatorial and normalized Laplacian based GSC. It also leads to applicability for GloVe embeddings of explanation methods developed originally bythe authors for Term Vector Space embeddings.
On Linear Representations and Pretraining Data Frequency in Language Models
Authors: Jack Merullo, Noah A. Smith, Sarah Wiegreffe, Yanai Elazar
Date: 2025-04-16 00:00:00
Tasks: 2k, In-Context Learning, Relation

Pretraining data has a direct impact on the behaviors and quality of language models (LMs), but we only understand the most basic principles of this relationship. While most work focuses on pretraining data's effect on downstream task behavior, we investigate its relationship to LM representations. Previous work has discovered that, in language models, some concepts are encoded `linearly' in the representations, but what factors cause these representations to form? We study the connection between pretraining data frequency and models' linear representations of factual relations. We find evidence that the formation of linear representations is strongly connected to pretraining term frequencies; specifically for subject-relation-object fact triplets, both subject-object co-occurrence frequency and in-context learning accuracy for the relation are highly correlated with linear representations. This is the case across all phases of pretraining. In OLMo-7B and GPT-J, we discover that a linear representation consistently (but not exclusively) forms when the subjects and objects within a relation co-occur at least 1k and 2k times, respectively, regardless of when these occurrences happen during pretraining. Finally, we train a regression model on measurements of linear representation quality in fully-trained LMs that can predict how often a term was seen in pretraining. Our model achieves low error even on inputs from a different model with a different pretraining dataset, providing a new method for estimating properties of the otherwise-unknown training data of closed-data models. We conclude that the strength of linear representations in LMs contains signal about the models' pretraining corpora that may provide new avenues for controlling and improving model behavior: particularly, manipulating the models' training data to meet specific frequency thresholds.