pwc-archive/papers-with-abstracts huggingface dataset:
Scaling Up Biomedical Vision-Language Models: Fine-Tuning, Instruction Tuning, and Multi-Modal Learning
Authors: Cheng Peng, Kai Zhang, Mengxian Lyu, Hongfang Liu, Lichao Sun, Yonghui Wu
Date: 2025-05-23 00:00:00
Tasks: Decoder, Image Captioning, image-classification, Image Classification, Language Modeling, Language Modelling, Question Answering, Text Summarization, Visual Question Answering, Zero-Shot Learning

To advance biomedical vison-language model capabilities through scaling up, fine-tuning, and instruction tuning, develop vision-language models with improved performance in handling long text, explore strategies to efficiently adopt vision language models for diverse multi-modal biomedical tasks, and examine the zero-shot learning performance. We developed two biomedical vision language models, BiomedGPT-Large and BiomedGPT-XLarge, based on an encoder-decoder-based transformer architecture. We fine-tuned the two models on 23 benchmark datasets from 6 multi-modal biomedical tasks including one image-only task (image classification), three language-only tasks (text understanding, text summarization and question answering), and two vision-language tasks (visual question answering and image captioning). We compared the developed scaled models with our previous BiomedGPT-Base model and existing prestigious models reported in the literature. We instruction-tuned the two models using a large-scale multi-modal biomedical instruction-tuning dataset and assessed the zero-shot learning performance and alignment accuracy.
RSRefSeg 2: Decoupling Referring Remote Sensing Image Segmentation with Foundation Models
Authors: Keyan Chen, Chenyang Liu, Bowen Chen, Jiafan Zhang, Zhengxia Zou, Zhenwei Shi
Date: 2025-07-08 00:00:00
Tasks: cross-modal alignment, Image Segmentation, Segmentation, Semantic Segmentation

Referring Remote Sensing Image Segmentation provides a flexible and fine-grained framework for remote sensing scene analysis via vision-language collaborative interpretation. Current approaches predominantly utilize a three-stage pipeline encompassing dual-modal encoding, cross-modal interaction, and pixel decoding. These methods demonstrate significant limitations in managing complex semantic relationships and achieving precise cross-modal alignment, largely due to their coupled processing mechanism that conflates target localization with boundary delineation. This architectural coupling amplifies error propagation under semantic ambiguity while restricting model generalizability and interpretability. To address these issues, we propose RSRefSeg 2, a decoupling paradigm that reformulates the conventional workflow into a collaborative dual-stage framework: coarse localization followed by fine segmentation. RSRefSeg 2 integrates CLIP's cross-modal alignment strength with SAM's segmentation generalizability through strategic foundation model collaboration. Specifically, CLIP is employed as the dual-modal encoder to activate target features within its pre-aligned semantic space and generate localization prompts. To mitigate CLIP's misactivation challenges in multi-entity scenarios described by referring texts, a cascaded second-order prompter is devised, which enhances precision through implicit reasoning via decomposition of text embeddings into complementary semantic subspaces. These optimized semantic prompts subsequently direct the SAM to generate pixel-level refined masks, thereby completing the semantic transmission pipeline. Extensive experiments (RefSegRS, RRSIS-D, and RISBench) demonstrate that RSRefSeg 2 surpasses contemporary methods in segmentation accuracy (+~3% gIoU) and complex semantic interpretation. Code is available at: https://github.com/KyanChen/RSRefSeg2.
Rethinking Layered Graphic Design Generation with a Top-Down Approach
Authors: Jingye Chen, Zhaowen Wang, Nanxuan Zhao, Li Zhang, Difan Liu, Jimei Yang, Qifeng Chen
Date: 2025-07-08 00:00:00

Graphic design is crucial for conveying ideas and messages. Designers usually organize their work into objects, backgrounds, and vectorized text layers to simplify editing. However, this workflow demands considerable expertise. With the rise of GenAI methods, an endless supply of high-quality graphic designs in pixel format has become more accessible, though these designs often lack editability. Despite this, non-layered designs still inspire human designers, influencing their choices in layouts and text styles, ultimately guiding the creation of layered designs. Motivated by this observation, we propose Accordion, a graphic design generation framework taking the first attempt to convert AI-generated designs into editable layered designs, meanwhile refining nonsensical AI-generated text with meaningful alternatives guided by user prompts. It is built around a vision language model (VLM) playing distinct roles in three curated stages. For each stage, we design prompts to guide the VLM in executing different tasks. Distinct from existing bottom-up methods (e.g., COLE and Open-COLE) that gradually generate elements to create layered designs, our approach works in a top-down manner by using the visually harmonious reference image as global guidance to decompose each layer. Additionally, it leverages multiple vision experts such as SAM and element removal models to facilitate the creation of graphic layers. We train our method using the in-house graphic design dataset Design39K, augmented with AI-generated design images coupled with refined ground truth created by a customized inpainting model. Experimental results and user studies by designers show that Accordion generates favorable results on the DesignIntention benchmark, including tasks such as text-to-template, adding text to background, and text de-rendering, and also excels in creating design variations.
OpenWorldSAM: Extending SAM2 for Universal Image Segmentation with Language Prompts
Authors: Shiting Xiao, Rishabh Kabra, Yuhang Li, DongHyun Lee, Joao Carreira, Priyadarshini Panda
Date: 2025-07-07 00:00:00
Tasks: Image Segmentation, Panoptic Segmentation, Semantic Segmentation

The ability to segment objects based on open-ended language prompts remains a critical challenge, requiring models to ground textual semantics into precise spatial masks while handling diverse and unseen categories. We present OpenWorldSAM, a framework that extends the prompt-driven Segment Anything Model v2 (SAM2) to open-vocabulary scenarios by integrating multi-modal embeddings extracted from a lightweight vision-language model (VLM). Our approach is guided by four key principles: i) Unified prompting: OpenWorldSAM supports a diverse range of prompts, including category-level and sentence-level language descriptions, providing a flexible interface for various segmentation tasks. ii) Efficiency: By freezing the pre-trained components of SAM2 and the VLM, we train only 4.5 million parameters on the COCO-stuff dataset, achieving remarkable resource efficiency. iii) Instance Awareness: We enhance the model's spatial understanding through novel positional tie-breaker embeddings and cross-attention layers, enabling effective segmentation of multiple instances. iv) Generalization: OpenWorldSAM exhibits strong zero-shot capabilities, generalizing well on unseen categories and an open vocabulary of concepts without additional training. Extensive experiments demonstrate that OpenWorldSAM achieves state-of-the-art performance in open-vocabulary semantic, instance, and panoptic segmentation across multiple benchmarks, including ADE20k, PASCAL, ScanNet, and SUN-RGBD.
SAMed-2: Selective Memory Enhanced Medical Segment Anything Model
Authors: Zhiling Yan, Sifan Song, Dingjie Song, Yiwei Li, Rong Zhou, Weixiang Sun, Zhennong Chen, Sekeun Kim, Hui Ren, Tianming Liu, Quanzheng Li, Xiang Li, Lifang He, Lichao Sun
Date: 2025-07-04 00:00:00
Tasks: Continual Learning, Image Segmentation, Medical Image Segmentation, Semantic Segmentation

Recent "segment anything" efforts show promise by learning from large-scale data, but adapting such models directly to medical images remains challenging due to the complexity of medical data, noisy annotations, and continual learning requirements across diverse modalities and anatomical structures. In this work, we propose SAMed-2, a new foundation model for medical image segmentation built upon the SAM-2 architecture. Specifically, we introduce a temporal adapter into the image encoder to capture image correlations and a confidence-driven memory mechanism to store high-certainty features for later retrieval. This memory-based strategy counters the pervasive noise in large-scale medical datasets and mitigates catastrophic forgetting when encountering new tasks or modalities. To train and evaluate SAMed-2, we curate MedBank-100k, a comprehensive dataset spanning seven imaging modalities and 21 medical segmentation tasks. Our experiments on both internal benchmarks and 10 external datasets demonstrate superior performance over state-of-the-art baselines in multi-task scenarios. The code is available at: https://github.com/ZhilingYan/Medical-SAM-Bench.
Causal-SAM-LLM: Large Language Models as Causal Reasoners for Robust Medical Segmentation
Authors: Tao Tang, Shijie Xu, Yiting Wu, Zhixiang Lu
Date: 2025-07-04 00:00:00
Tasks: Anatomy, Disentanglement, Image Segmentation, Medical Image Segmentation, Semantic Segmentation

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between anatomical content and domain-specific imaging styles. To overcome this fundamental challenge, we introduce Causal-SAM-LLM, a novel framework that elevates Large Language Models (LLMs) to the role of causal reasoners. Our framework, built upon a frozen Segment Anything Model (SAM) encoder, incorporates two synergistic innovations. First, Linguistic Adversarial Disentanglement (LAD) employs a Vision-Language Model to generate rich, textual descriptions of confounding image styles. By training the segmentation model's features to be contrastively dissimilar to these style descriptions, it learns a representation robustly purged of non-causal information. Second, Test-Time Causal Intervention (TCI) provides an interactive mechanism where an LLM interprets a clinician's natural language command to modulate the segmentation decoder's features in real-time, enabling targeted error correction. We conduct an extensive empirical evaluation on a composite benchmark from four public datasets (BTCV, CHAOS, AMOS, BraTS), assessing generalization under cross-scanner, cross-modality, and cross-anatomy settings. Causal-SAM-LLM establishes a new state of the art in out-of-distribution (OOD) robustness, improving the average Dice score by up to 6.2 points and reducing the Hausdorff Distance by 15.8 mm over the strongest baseline, all while using less than 9% of the full model's trainable parameters. Our work charts a new course for building robust, efficient, and interactively controllable medical AI systems.
Weakly-supervised Contrastive Learning with Quantity Prompts for Moving Infrared Small Target Detection
Authors: Weiwei Duan, Luping Ji, Shengjia Chen, Sicheng Zhu, Jianghong Huang, Mao Ye
Date: 2025-07-03 00:00:00
Tasks: Contrastive Learning, object-detection, Object Detection

Different from general object detection, moving infrared small target detection faces huge challenges due to tiny target size and weak background contrast.Currently, most existing methods are fully-supervised, heavily relying on a large number of manual target-wise annotations. However, manually annotating video sequences is often expensive and time-consuming, especially for low-quality infrared frame images. Inspired by general object detection, non-fully supervised strategies ($e.g.$, weakly supervised) are believed to be potential in reducing annotation requirements. To break through traditional fully-supervised frameworks, as the first exploration work, this paper proposes a new weakly-supervised contrastive learning (WeCoL) scheme, only requires simple target quantity prompts during model training.Specifically, in our scheme, based on the pretrained segment anything model (SAM), a potential target mining strategy is designed to integrate target activation maps and multi-frame energy accumulation.Besides, contrastive learning is adopted to further improve the reliability of pseudo-labels, by calculating the similarity between positive and negative samples in feature subspace.Moreover, we propose a long-short term motion-aware learning scheme to simultaneously model the local motion patterns and global motion trajectory of small targets.The extensive experiments on two public datasets (DAUB and ITSDT-15K) verify that our weakly-supervised scheme could often outperform early fully-supervised methods. Even, its performance could reach over 90\% of state-of-the-art (SOTA) fully-supervised ones.
ViRefSAM: Visual Reference-Guided Segment Anything Model for Remote Sensing Segmentation
Authors: Hanbo Bi, Yulong Xu, Ya Li, Yongqiang Mao, Boyuan Tong, Chongyang Li, Chunbo Lang, Wenhui Diao, Hongqi Wang, Yingchao Feng, Xian Sun
Date: 2025-07-03 00:00:00
Tasks: Few-Shot Learning, Segmentation

The Segment Anything Model (SAM), with its prompt-driven paradigm, exhibits strong generalization in generic segmentation tasks. However, applying SAM to remote sensing (RS) images still faces two major challenges. First, manually constructing precise prompts for each image (e.g., points or boxes) is labor-intensive and inefficient, especially in RS scenarios with dense small objects or spatially fragmented distributions. Second, SAM lacks domain adaptability, as it is pre-trained primarily on natural images and struggles to capture RS-specific semantics and spatial characteristics, especially when segmenting novel or unseen classes. To address these issues, inspired by few-shot learning, we propose ViRefSAM, a novel framework that guides SAM utilizing only a few annotated reference images that contain class-specific objects. Without requiring manual prompts, ViRefSAM enables automatic segmentation of class-consistent objects across RS images. Specifically, ViRefSAM introduces two key components while keeping SAM's original architecture intact: (1) a Visual Contextual Prompt Encoder that extracts class-specific semantic clues from reference images and generates object-aware prompts via contextual interaction with target images; and (2) a Dynamic Target Alignment Adapter, integrated into SAM's image encoder, which mitigates the domain gap by injecting class-specific semantics into target image features, enabling SAM to dynamically focus on task-relevant regions. Extensive experiments on three few-shot segmentation benchmarks, including iSAID-5$^i$, LoveDA-2$^i$, and COCO-20$^i$, demonstrate that ViRefSAM enables accurate and automatic segmentation of unseen classes by leveraging only a few reference images and consistently outperforms existing few-shot segmentation methods across diverse datasets.
NOCTIS: Novel Object Cyclic Threshold based Instance Segmentation
Authors: Max Gandyra, Alessandro Santonicola, Michael Beetz
Date: 2025-07-02 00:00:00
Tasks: Instance Segmentation, Object, Segmentation, Semantic Segmentation

Instance segmentation of novel objects instances in RGB images, given some example images for each object, is a well known problem in computer vision. Designing a model general enough to be employed, for all kinds of novel objects, without (re-) training, has proven to be a difficult task. To handle this, we propose a simple, yet powerful, framework, called: Novel Object Cyclic Threshold based Instance Segmentation (NOCTIS). This work stems from and improves upon previous ones like CNOS, SAM-6D and NIDS-Net; thus, it also leverages on recent vision foundation models, namely: Grounded-SAM 2 and DINOv2. It utilises Grounded-SAM 2 to obtain object proposals with precise bounding boxes and their corresponding segmentation masks; while DINOv2's zero-shot capabilities are employed to generate the image embeddings. The quality of those masks, together with their embeddings, is of vital importance to our approach; as the proposal-object matching is realized by determining an object matching score based on the similarity of the class embeddings and the average maximum similarity of the patch embeddings. Differently to SAM-6D, calculating the latter involves a prior patch filtering based on the distance between each patch and its corresponding cyclic/roundtrip patch in the image grid. Furthermore, the average confidence of the proposals' bounding box and mask is used as an additional weighting factor for the object matching score. We empirically show that NOCTIS, without further training/fine tuning, outperforms the best RGB and RGB-D methods on the seven core datasets of the BOP 2023 challenge for the "Model-based 2D segmentation of unseen objects" task.
Autoadaptive Medical Segment Anything Model
Authors: Tyler Ward, Meredith K. Owen, O'Kira Coleman, Brian Noehren, Abdullah-Al-Zubaer Imran
Date: 2025-07-02 00:00:00
Tasks: Image Segmentation, Medical Image Segmentation, model, Segmentation, Semantic Segmentation

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual annotation, which can be an expensive, time-consuming, and error-prone process. This signals a need for accurate, automatic, and annotation-efficient methods of training these models. We propose ADA-SAM (automated, domain-specific, and adaptive segment anything model), a novel multitask learning framework for medical image segmentation that leverages class activation maps from an auxiliary classifier to guide the predictions of the semi-supervised segmentation branch, which is based on the Segment Anything (SAM) framework. Additionally, our ADA-SAM model employs a novel gradient feedback mechanism to create a learnable connection between the segmentation and classification branches by using the segmentation gradients to guide and improve the classification predictions. We validate ADA-SAM on real-world clinical data collected during rehabilitation trials, and demonstrate that our proposed method outperforms both fully-supervised and semi-supervised baselines by double digits in limited label settings. Our code is available at: https://github.com/tbwa233/ADA-SAM.
Boosting Adversarial Transferability Against Defenses via Multi-Scale Transformation
Authors: Zihong Guo, Chen Wan, Yayin Zheng, Hailing Kuang, Xiaohai Lu
Date: 2025-07-02 00:00:00

The transferability of adversarial examples poses a significant security challenge for deep neural networks, which can be attacked without knowing anything about them. In this paper, we propose a new Segmented Gaussian Pyramid (SGP) attack method to enhance the transferability, particularly against defense models. Unlike existing methods that generally focus on single-scale images, our approach employs Gaussian filtering and three types of downsampling to construct a series of multi-scale examples. Then, the gradients of the loss function with respect to each scale are computed, and their average is used to determine the adversarial perturbations. The proposed SGP can be considered an input transformation with high extensibility that is easily integrated into most existing adversarial attacks. Extensive experiments demonstrate that in contrast to the state-of-the-art methods, SGP significantly enhances attack success rates against black-box defense models, with average attack success rates increasing by 2.3% to 32.6%, based only on transferability.
Mamba Guided Boundary Prior Matters: A New Perspective for Generalized Polyp Segmentation
Authors: Tapas K. Dutta, Snehashis Majhi, Deepak Ranjan Nayak, Debesh Jha
Date: 2025-07-02 00:00:00
Tasks: Mamba, Segmentation

Polyp segmentation in colonoscopy images is crucial for early detection and diagnosis of colorectal cancer. However, this task remains a significant challenge due to the substantial variations in polyp shape, size, and color, as well as the high similarity between polyps and surrounding tissues, often compounded by indistinct boundaries. While existing encoder-decoder CNN and transformer-based approaches have shown promising results, they struggle with stable segmentation performance on polyps with weak or blurry boundaries. These methods exhibit limited abilities to distinguish between polyps and non-polyps and capture essential boundary cues. Moreover, their generalizability still falls short of meeting the demands of real-time clinical applications. To address these limitations, we propose SAM-MaGuP, a groundbreaking approach for robust polyp segmentation. By incorporating a boundary distillation module and a 1D-2D Mamba adapter within the Segment Anything Model (SAM), SAM-MaGuP excels at resolving weak boundary challenges and amplifies feature learning through enriched global contextual interactions. Extensive evaluations across five diverse datasets reveal that SAM-MaGuP outperforms state-of-the-art methods, achieving unmatched segmentation accuracy and robustness. Our key innovations, a Mamba-guided boundary prior and a 1D-2D Mamba block, set a new benchmark in the field, pushing the boundaries of polyp segmentation to new heights.
Mask-aware Text-to-Image Retrieval: Referring Expression Segmentation Meets Cross-modal Retrieval
Authors: Li-Cheng Shen, Jih-Kang Hsieh, Wei-Hua Li, Chu-Song Chen
Date: 2025-06-28 00:00:00
Tasks: Cross-Modal Retrieval, Image Captioning, Image Retrieval, Large Language Model, Multimodal Large Language Model, Object, Object Localization, Referring Expression, Referring Expression Segmentation, Reranking, Retrieval, Segmentation, Semantic Segmentation

Text-to-image retrieval (TIR) aims to find relevant images based on a textual query, but existing approaches are primarily based on whole-image captions and lack interpretability. Meanwhile, referring expression segmentation (RES) enables precise object localization based on natural language descriptions but is computationally expensive when applied across large image collections. To bridge this gap, we introduce Mask-aware TIR (MaTIR), a new task that unifies TIR and RES, requiring both efficient image search and accurate object segmentation. To address this task, we propose a two-stage framework, comprising a first stage for segmentation-aware image retrieval and a second stage for reranking and object grounding with a multimodal large language model (MLLM). We leverage SAM 2 to generate object masks and Alpha-CLIP to extract region-level embeddings offline at first, enabling effective and scalable online retrieval. Secondly, MLLM is used to refine retrieval rankings and generate bounding boxes, which are matched to segmentation masks. We evaluate our approach on COCO and D$^3$ datasets, demonstrating significant improvements in both retrieval accuracy and segmentation quality over previous methods.