pwc-archive/papers-with-abstracts huggingface dataset:
FedSCA: Federated Tuning with Similarity-guided Collaborative Aggregation for Heterogeneous Medical Image Segmentation
Authors: Yumin Zhang, Yan Gao, Haoran Duan, Hanqing Guo, Tejal Shah, Rajiv Ranjan, Bo Wei
Date: 2025-03-19 00:00:00
Tasks: Computational Efficiency, Federated Learning, Image Segmentation, Medical Image Segmentation, parameter-efficient fine-tuning, Semantic Segmentation

Transformer-based foundation models (FMs) have recently demonstrated remarkable performance in medical image segmentation. However, scaling these models is challenging due to the limited size of medical image datasets within isolated hospitals, where data centralization is restricted due to privacy concerns. These constraints, combined with the data-intensive nature of FMs, hinder their broader application. Integrating federated learning (FL) with foundation models (FLFM) fine-tuning offers a potential solution to these challenges by enabling collaborative model training without data sharing, thus allowing FMs to take advantage of a diverse pool of sensitive medical image data across hospitals/clients. However, non-independent and identically distributed (non-IID) data among clients, paired with computational and communication constraints in federated environments, presents an additional challenge that limits further performance improvements and remains inadequately addressed in existing studies. In this work, we propose a novel FLFM fine-tuning framework, \underline{\textbf{Fed}}erated tuning with \underline{\textbf{S}}imilarity-guided \underline{\textbf{C}}ollaborative \underline{\textbf{A}}ggregation (FedSCA), encompassing all phases of the FL process. This includes (1) specially designed parameter-efficient fine-tuning (PEFT) for local client training to enhance computational efficiency; (2) partial low-level adapter transmission for communication efficiency; and (3) similarity-guided collaborative aggregation (SGCA) on the server side to address non-IID issues. Extensive experiments on three FL benchmarks for medical image segmentation demonstrate the effectiveness of our proposed FedSCA, establishing new SOTA performance.
Context-Aware Vision Language Foundation Models for Ocular Disease Screening in Retinal Images
Authors: Lucie Berger, Mathieu Lamard, Philippe Zhang, Laurent Borderie, Alexandre Le Guilcher, Pascale Massin, Béatrice Cochener, Gwenolé Quellec, Sarah Matta
Date: 2025-03-19 00:00:00

Foundation models are large-scale versatile systems trained on vast quantities of diverse data to learn generalizable representations. Their adaptability with minimal fine-tuning makes them particularly promising for medical imaging, where data variability and domain shifts are major challenges. Currently, two types of foundation models dominate the literature: self-supervised models and more recent vision-language models. In this study, we advance the application of vision-language foundation (VLF) models for ocular disease screening using the OPHDIAT dataset, which includes nearly 700,000 fundus photographs from a French diabetic retinopathy (DR) screening network. This dataset provides extensive clinical data (patient-specific information such as diabetic health conditions, and treatments), labeled diagnostics, ophthalmologists text-based findings, and multiple retinal images for each examination. Building on the FLAIR model $\unicode{x2013}$ a VLF model for retinal pathology classification $\unicode{x2013}$ we propose novel context-aware VLF models (e.g jointly analyzing multiple images from the same visit or taking advantage of past diagnoses and contextual data) to fully leverage the richness of the OPHDIAT dataset and enhance robustness to domain shifts. Our approaches were evaluated on both in-domain (a testing subset of OPHDIAT) and out-of-domain data (public datasets) to assess their generalization performance. Our model demonstrated improved in-domain performance for DR grading, achieving an area under the curve (AUC) ranging from 0.851 to 0.9999, and generalized well to ocular disease detection on out-of-domain data (AUC: 0.631-0.913).
Texture-Aware StarGAN for CT data harmonisation
Authors: Francesco Di Feola, Ludovica Pompilio, Cecilia Assolito, Valerio Guarrasi, Paolo Soda
Date: 2025-03-19 00:00:00
Tasks: Computed Tomography (CT), Medical Diagnosis, Style Transfer

Computed Tomography (CT) plays a pivotal role in medical diagnosis; however, variability across reconstruction kernels hinders data-driven approaches, such as deep learning models, from achieving reliable and generalized performance. To this end, CT data harmonization has emerged as a promising solution to minimize such non-biological variances by standardizing data across different sources or conditions. In this context, Generative Adversarial Networks (GANs) have proved to be a powerful framework for harmonization, framing it as a style-transfer problem. However, GAN-based approaches still face limitations in capturing complex relationships within the images, which are essential for effective harmonization. In this work, we propose a novel texture-aware StarGAN for CT data harmonization, enabling one-to-many translations across different reconstruction kernels. Although the StarGAN model has been successfully applied in other domains, its potential for CT data harmonization remains unexplored. Furthermore, our approach introduces a multi-scale texture loss function that embeds texture information across different spatial and angular scales into the harmonization process, effectively addressing kernel-induced texture variations. We conducted extensive experimentation on a publicly available dataset, utilizing a total of 48667 chest CT slices from 197 patients distributed over three different reconstruction kernels, demonstrating the superiority of our method over the baseline StarGAN.
A Novel Channel Boosted Residual CNN-Transformer with Regional-Boundary Learning for Breast Cancer Detection
Authors: Aamir Mehmood, Yue Hu, Saddam Hussain Khan
Date: 2025-03-19 00:00:00
Tasks: Breast Cancer Detection, Computational Efficiency, Transfer Learning

Recent advancements in detecting tumors using deep learning on breast ultrasound images (BUSI) have demonstrated significant success. Deep CNNs and vision-transformers (ViTs) have demonstrated individually promising initial performance. However, challenges related to model complexity and contrast, texture, and tumor morphology variations introduce uncertainties that hinder the effectiveness of current methods. This study introduces a novel hybrid framework, CB-Res-RBCMT, combining customized residual CNNs and new ViT components for detailed BUSI cancer analysis. The proposed RBCMT uses stem convolution blocks with CNN Meet Transformer (CMT) blocks, followed by new Regional and boundary (RB) feature extraction operations for capturing contrast and morphological variations. Moreover, the CMT block incorporates global contextual interactions through multi-head attention, enhancing computational efficiency with a lightweight design. Additionally, the customized inverse residual and stem CNNs within the CMT effectively extract local texture information and handle vanishing gradients. Finally, the new channel-boosted (CB) strategy enriches the feature diversity of the limited dataset by combining the original RBCMT channels with transfer learning-based residual CNN-generated maps. These diverse channels are processed through a spatial attention block for optimal pixel selection, reducing redundancy and improving the discrimination of minor contrast and texture variations. The proposed CB-Res-RBCMT achieves an F1-score of 95.57%, accuracy of 95.63%, sensitivity of 96.42%, and precision of 94.79% on the standard harmonized stringent BUSI dataset, outperforming existing ViT and CNN methods. These results demonstrate the versatility of our integrated CNN-Transformer framework in capturing diverse features and delivering superior performance in BUSI cancer diagnosis.
Ultrasound Image-to-Video Synthesis via Latent Dynamic Diffusion Models
Authors: Tingxiu Chen, Yilei Shi, Zixuan Zheng, Bingcong Yan, Jingliang Hu, Xiao Xiang Zhu, Lichao Mou
Date: 2025-03-19 00:00:00
Tasks: Classification, Data Augmentation, Video Classification

Ultrasound video classification enables automated diagnosis and has emerged as an important research area. However, publicly available ultrasound video datasets remain scarce, hindering progress in developing effective video classification models. We propose addressing this shortage by synthesizing plausible ultrasound videos from readily available, abundant ultrasound images. To this end, we introduce a latent dynamic diffusion model (LDDM) to efficiently translate static images to dynamic sequences with realistic video characteristics. We demonstrate strong quantitative results and visually appealing synthesized videos on the BUSV benchmark. Notably, training video classification models on combinations of real and LDDM-synthesized videos substantially improves performance over using real data alone, indicating our method successfully emulates dynamics critical for discrimination. Our image-to-video approach provides an effective data augmentation solution to advance ultrasound video analysis. Code is available at https://github.com/MedAITech/U_I2V.
FetalFlex: Anatomy-Guided Diffusion Model for Flexible Control on Fetal Ultrasound Image Synthesis
Authors: Yaofei Duan, Tao Tan, Zhiyuan Zhu, Yuhao Huang, Yuanji Zhang, Rui Gao, Patrick Cheong-Iao Pang, Xinru Gao, Guowei Tao, Xiang Cong, Zhou Li, Lianying Liang, Guangzhi He, Linliang Yin, Xuedong Deng, Xin Yang, Dong Ni
Date: 2025-03-19 00:00:00
Tasks: Anatomy, Anomaly Detection, counterfactual, Diagnostic, Image Generation

Fetal ultrasound (US) examinations require the acquisition of multiple planes, each providing unique diagnostic information to evaluate fetal development and screening for congenital anomalies. However, obtaining a comprehensive, multi-plane annotated fetal US dataset remains challenging, particularly for rare or complex anomalies owing to their low incidence and numerous subtypes. This poses difficulties in training novice radiologists and developing robust AI models, especially for detecting abnormal fetuses. In this study, we introduce a Flexible Fetal US image generation framework (FetalFlex) to address these challenges, which leverages anatomical structures and multimodal information to enable controllable synthesis of fetal US images across diverse planes. Specifically, FetalFlex incorporates a pre-alignment module to enhance controllability and introduces a repaint strategy to ensure consistent texture and appearance. Moreover, a two-stage adaptive sampling strategy is developed to progressively refine image quality from coarse to fine levels. We believe that FetalFlex is the first method capable of generating both in-distribution normal and out-of-distribution abnormal fetal US images, without requiring any abnormal data. Experiments on multi-center datasets demonstrate that FetalFlex achieved state-of-the-art performance across multiple image quality metrics. A reader study further confirms the close alignment of the generated results with expert visual assessments. Furthermore, synthetic images by FetalFlex significantly improve the performance of six typical deep models in downstream classification and anomaly detection tasks. Lastly, FetalFlex's anatomy-level controllable generation offers a unique advantage for anomaly simulation and creating paired or counterfactual data at the pixel level. The demo is available at: https://dyf1023.github.io/FetalFlex/.
Degradation Alchemy: Self-Supervised Unknown-to-Known Transformation for Blind Hyperspectral Image Fusion
Authors: He Huang, Yong Chen, Yujun Guo, wei he
Date: 2025-03-19 00:00:00

Hyperspectral image (HSI) fusion is an efficient technique that combines low-resolution HSI (LR-HSI) and high-resolution multispectral images (HR-MSI) to generate high-resolution HSI (HR-HSI). Existing supervised learning methods (SLMs) can yield promising results when test data degradation matches the training ones, but they face challenges in generalizing to unknown degradations. To unleash the potential and generalization ability of SLMs, we propose a novel self-supervised unknown-to-known degradation transformation framework (U2K) for blind HSI fusion, which adaptively transforms unknown degradation into the same type of degradation as those handled by pre-trained SLMs. Specifically, the proposed U2K framework consists of: (1) spatial and spectral Degradation Wrapping (DW) modules that map HR-HSI to unknown degraded HR-MSI and LR-HSI, and (2) Degradation Transformation (DT) modules that convert these wrapped data into predefined degradation patterns. The transformed HR-MSI and LR-HSI pairs are then processed by a pre-trained network to reconstruct the target HR-HSI. We train the U2K framework in a self-supervised manner using consistency loss and greedy alternating optimization, significantly improving the flexibility of blind HSI fusion. Extensive experiments confirm the effectiveness of our proposed U2K framework in boosting the adaptability of five existing SLMs under various degradation settings and surpassing state-of-the-art blind methods.
Involution and BSConv Multi-Depth Distillation Network for Lightweight Image Super-Resolution
Authors: Akram Khatami-Rizi, Ahmad Mahmoudi-Aznaveh
Date: 2025-03-18 00:00:00
Tasks: Computational Efficiency, Image Super-Resolution, SSIM, Super-Resolution

Single Image Super-Resolution (SISR) aims to reconstruct high-resolution (HR) images from low-resolution (LR) inputs. Deep learning, especially Convolutional Neural Networks (CNNs), has advanced SISR. However, increasing network depth increases parameters, and memory usage, and slows training, which is problematic for resource-limited devices. To address this, lightweight models are developed to balance accuracy and efficiency. We propose the Involution & BSConv Multi-Depth Distillation Network (IBMDN), combining Involution & BSConv Multi-Depth Distillation Block (IBMDB) and the Contrast and High-Frequency Attention Block (CHFAB). IBMDB integrates Involution and BSConv to balance computational efficiency and feature extraction. CHFAB enhances high-frequency details for better visual quality. IBMDB is compatible with other SISR architectures and reduces complexity, improving evaluation metrics like PSNR and SSIM. In transformer-based models, IBMDB reduces memory usage while improving feature extraction. In GANs, it enhances perceptual quality, balancing pixel-level accuracy with perceptual details. Our experiments show that the method achieves high accuracy with minimal computational cost. The code is available at GitHub.
Whole-Body Image-to-Image Translation for a Virtual Scanner in a Healthcare Digital Twin
Authors: Valerio Guarrasi, Francesco Di Feola, Rebecca Restivo, Lorenzo Tronchin, Paolo Soda
Date: 2025-03-18 00:00:00
Tasks: Computed Tomography (CT), Image Generation, Image-to-Image Translation, Translation

Generating positron emission tomography (PET) images from computed tomography (CT) scans via deep learning offers a promising pathway to reduce radiation exposure and costs associated with PET imaging, improving patient care and accessibility to functional imaging. Whole-body image translation presents challenges due to anatomical heterogeneity, often limiting generalized models. We propose a framework that segments whole-body CT images into four regions-head, trunk, arms, and legs-and uses district-specific Generative Adversarial Networks (GANs) for tailored CT-to-PET translation. Synthetic PET images from each region are stitched together to reconstruct the whole-body scan. Comparisons with a baseline non-segmented GAN and experiments with Pix2Pix and CycleGAN architectures tested paired and unpaired scenarios. Quantitative evaluations at district, whole-body, and lesion levels demonstrated significant improvements with our district-specific GANs. Pix2Pix yielded superior metrics, ensuring precise, high-quality image synthesis. By addressing anatomical heterogeneity, this approach achieves state-of-the-art results in whole-body CT-to-PET translation. This methodology supports healthcare Digital Twins by enabling accurate virtual PET scans from CT data, creating virtual imaging representations to monitor, predict, and optimize health outcomes.
Core-Periphery Principle Guided State Space Model for Functional Connectome Classification
Authors: Minheng Chen, Xiaowei Yu, Jing Zhang, Tong Chen, Chao Cao, Yan Zhuang, Yanjun Lyu, Lu Zhang, Tianming Liu, Dajiang Zhu
Date: 2025-03-18 00:00:00
Tasks: Functional Connectivity, Mamba, Mixture-of-Experts, Representation Learning

Understanding the organization of human brain networks has become a central focus in neuroscience, particularly in the study of functional connectivity, which plays a crucial role in diagnosing neurological disorders. Advances in functional magnetic resonance imaging and machine learning techniques have significantly improved brain network analysis. However, traditional machine learning approaches struggle to capture the complex relationships between brain regions, while deep learning methods, particularly Transformer-based models, face computational challenges due to their quadratic complexity in long-sequence modeling. To address these limitations, we propose a Core-Periphery State-Space Model (CP-SSM), an innovative framework for functional connectome classification. Specifically, we introduce Mamba, a selective state-space model with linear complexity, to effectively capture long-range dependencies in functional brain networks. Furthermore, inspired by the core-periphery (CP) organization, a fundamental characteristic of brain networks that enhances efficient information transmission, we design CP-MoE, a CP-guided Mixture-of-Experts that improves the representation learning of brain connectivity patterns. We evaluate CP-SSM on two benchmark fMRI datasets: ABIDE and ADNI. Experimental results demonstrate that CP-SSM surpasses Transformer-based models in classification performance while significantly reducing computational complexity. These findings highlight the effectiveness and efficiency of CP-SSM in modeling brain functional connectivity, offering a promising direction for neuroimaging-based neurological disease diagnosis.
Analysis of human visual field information using machine learning methods and assessment of their accuracy
Authors: A. I. Medvedeva, V. V. Bakutkin
Date: 2025-03-18 00:00:00
Tasks: Binary Classification

Subject of research: is the study of methods for analyzing perimetric images for the diagnosis and control of glaucoma diseases. Objects of research: is a dataset collected on the ophthalmological perimeter with the results of various patient pathologies, since the ophthalmological community is acutely aware of the issue of disease control and import substitution. [5]. Purpose of research: is to consider various machine learning methods that can classify glaucoma. This is possible thanks to the classifier built after labeling the dataset. It is able to determine from the image whether the visual fields depicted on it are the results of the impact of glaucoma on the eyes or other visual diseases. Earlier in the work [3], a dataset was described that was collected on the Tomey perimeter. The average age of the examined patients ranged from 30 to 85 years. Methods of research: machine learning methods for classifying image results (stochastic gradient descent, logistic regression, random forest, naive Bayes). Main results of research: the result of the study is computer modeling that can determine from the image whether the result is glaucoma or another disease (binary classification).
Novel AI-Based Quantification of Breast Arterial Calcification to Predict Cardiovascular Risk
Authors: Theodorus Dapamede, Aisha Urooj, Vedant Joshi, Gabrielle Gershon, Frank Li, Mohammadreza Chavoshi, Beatrice Brown-Mulry, Rohan Satya Isaac, Aawez Mansuri, Chad Robichaux, Chadi Ayoub, Reza Arsanjani, Laurence Sperling, Judy Gichoya, Marly van Assen, Charles W. ONeill, Imon Banerjee, Hari Trivedi
Date: 2025-03-17 00:00:00
Tasks: All

Women are underdiagnosed and undertreated for cardiovascular disease. Automatic quantification of breast arterial calcification on screening mammography can identify women at risk for cardiovascular disease and enable earlier treatment and management of disease. In this retrospective study of 116,135 women from two healthcare systems, a transformer-based neural network quantified BAC severity (no BAC, mild, moderate, and severe) on screening mammograms. Outcomes included major adverse cardiovascular events (MACE) and all-cause mortality. BAC severity was independently associated with MACE after adjusting for cardiovascular risk factors, with increasing hazard ratios from mild (HR 1.18-1.22), moderate (HR 1.38-1.47), to severe BAC (HR 2.03-2.22) across datasets (all p<0.001). This association remained significant across all age groups, with even mild BAC indicating increased risk in women under 50. BAC remained an independent predictor when analyzed alongside ASCVD risk scores, showing significant associations with myocardial infarction, stroke, heart failure, and mortality (all p<0.005). Automated BAC quantification enables opportunistic cardiovascular risk assessment during routine mammography without additional radiation or cost. This approach provides value beyond traditional risk factors, particularly in younger women, offering potential for early CVD risk stratification in the millions of women undergoing annual mammography.
The Impact of Artificial Intelligence on Emergency Medicine: A Review of Recent Advances
Authors: Gustavo Correia, Victor Alves, Paulo Novais
Date: 2025-03-17 00:00:00
Tasks: Diagnostic

Artificial Intelligence (AI) is revolutionizing emergency medicine by enhancing diagnostic processes and improving patient outcomes. This article provides a review of the current applications of AI in emergency imaging studies, focusing on the last five years of advancements. AI technologies, particularly machine learning and deep learning, are pivotal in interpreting complex imaging data, offering rapid, accurate diagnoses and potentially surpassing traditional diagnostic methods. Studies highlighted within the article demonstrate AI's capabilities in accurately detecting conditions such as fractures, pneumothorax, and pulmonary diseases from various imaging modalities including X-rays, CT scans, and MRIs. Furthermore, AI's ability to predict clinical outcomes like mechanical ventilation needs illustrates its potential in crisis resource optimization. Despite these advancements, the integration of AI into clinical practice presents challenges such as data privacy, algorithmic bias, and the need for extensive validation across diverse settings. This review underscores the transformative potential of AI in emergency settings, advocating for a future where AI and clinical expertise synergize to elevate patient care standards.