pwc-archive/papers-with-abstracts huggingface dataset:
U2AD: Uncertainty-based Unsupervised Anomaly Detection Framework for Detecting T2 Hyperintensity in MRI Spinal Cord
Authors: Qi Zhang, Xiuyuan Chen, Ziyi He, Kun Wang, Lianming Wu, Hongxing Shen, Jianqi Sun
Date: 2025-03-17 00:00:00
Tasks: Anomaly Detection, Lesion Detection, Unsupervised Anomaly Detection

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise in lesion detection, but most supervised approaches are heavily dependent on large, annotated datasets. Unsupervised anomaly detection (UAD) offers a compelling alternative by eliminating the need for abnormal data annotations. However, existing UAD methods rely on curated normal datasets and their performance frequently deteriorates when applied to clinical datasets due to domain shifts. We propose an Uncertainty-based Unsupervised Anomaly Detection framework, termed U2AD, to address these limitations. Unlike traditional methods, U2AD is designed to be trained and tested within the same clinical dataset, following a "mask-and-reconstruction" paradigm built on a Vision Transformer-based architecture. We introduce an uncertainty-guided masking strategy to resolve task conflicts between normal reconstruction and anomaly detection to achieve an optimal balance. Specifically, we employ a Monte-Carlo sampling technique to estimate reconstruction uncertainty mappings during training. By iteratively optimizing reconstruction training under the guidance of both epistemic and aleatoric uncertainty, U2AD reduces overall reconstruction variance while emphasizing regions. Experimental results demonstrate that U2AD outperforms existing supervised and unsupervised methods in patient-level identification and segment-level localization tasks. This framework establishes a new benchmark for incorporating uncertainty guidance into UAD, highlighting its clinical utility in addressing domain shifts and task conflicts in medical image anomaly detection. Our code is available: https://github.com/zhibaishouheilab/U2AD
Subgroup Performance of a Commercial Digital Breast Tomosynthesis Model for Breast Cancer Detection
Authors: Beatrice Brown-Mulry, Rohan Satya Isaac, Sang Hyup Lee, Ambika Seth, KyungJee Min, Theo Dapamede, Frank Li, Aawez Mansuri, Minjae Woo, Christian Allison Fauria-Robinson, Bhavna Paryani, Judy Wawira Gichoya, Hari Trivedi
Date: 2025-03-17 00:00:00
Tasks: Breast Cancer Detection

While research has established the potential of AI models for mammography to improve breast cancer screening outcomes, there have not been any detailed subgroup evaluations performed to assess the strengths and weaknesses of commercial models for digital breast tomosynthesis (DBT) imaging. This study presents a granular evaluation of the Lunit INSIGHT DBT model on a large retrospective cohort of 163,449 screening mammography exams from the Emory Breast Imaging Dataset (EMBED). Model performance was evaluated in a binary context with various negative exam types (162,081 exams) compared against screen detected cancers (1,368 exams) as the positive class. The analysis was stratified across demographic, imaging, and pathologic subgroups to identify potential disparities. The model achieved an overall AUC of 0.91 (95% CI: 0.90-0.92) with a precision of 0.08 (95% CI: 0.08-0.08), and a recall of 0.73 (95% CI: 0.71-0.76). Performance was found to be robust across demographics, but cases with non-invasive cancers (AUC: 0.85, 95% CI: 0.83-0.87), calcifications (AUC: 0.80, 95% CI: 0.78-0.82), and dense breast tissue (AUC: 0.90, 95% CI: 0.88-0.91) were associated with significantly lower performance compared to other groups. These results highlight the need for detailed evaluation of model characteristics and vigilance in considering adoption of new tools for clinical deployment.
LEAVS: An LLM-based Labeler for Abdominal CT Supervision
Authors: Ricardo Bigolin Lanfredi, Yan Zhuang, Mark Finkelstein, Praveen Thoppey Srinivasan Balamuralikrishna, Luke Krembs, Brandon Khoury, Arthi Reddy, Pritam Mukherjee, Neil M. Rofsky, Ronald M. Summers
Date: 2025-03-17 00:00:00
Tasks: Anatomy, Large Language Model, Multiple-choice

Extracting structured labels from radiology reports has been employed to create vision models to simultaneously detect several types of abnormalities. However, existing works focus mainly on the chest region. Few works have been investigated on abdominal radiology reports due to more complex anatomy and a wider range of pathologies in the abdomen. We propose LEAVS (Large language model Extractor for Abdominal Vision Supervision). This labeler can annotate the certainty of presence and the urgency of seven types of abnormalities for nine abdominal organs on CT radiology reports. To ensure broad coverage, we chose abnormalities that encompass most of the finding types from CT reports. Our approach employs a specialized chain-of-thought prompting strategy for a locally-run LLM using sentence extraction and multiple-choice questions in a tree-based decision system. We demonstrate that the LLM can extract several abnormality types across abdominal organs with an average F1 score of 0.89, significantly outperforming competing labelers and humans. Additionally, we show that extraction of urgency labels achieved performance comparable to human annotations. Finally, we demonstrate that the abnormality labels contain valuable information for training a single vision model that classifies several organs as normal or abnormal. We release our code and structured annotations for a public CT dataset containing over 1,000 CT volumes.
Integrating AI for Human-Centric Breast Cancer Diagnostics: A Multi-Scale and Multi-View Swin Transformer Framework
Authors: Farnoush Bayatmakou, Reza Taleei, Milad Amir Toutounchian, Arash Mohammadi
Date: 2025-03-17 00:00:00
Tasks: Diagnostic

Despite advancements in Computer-Aided Diagnosis (CAD) systems, breast cancer remains one of the leading causes of cancer-related deaths among women worldwide. Recent breakthroughs in Artificial Intelligence (AI) have shown significant promise in development of advanced Deep Learning (DL) architectures for breast cancer diagnosis through mammography. In this context, the paper focuses on the integration of AI within a Human-Centric workflow to enhance breast cancer diagnostics. Key challenges are, however, largely overlooked such as reliance on detailed tumor annotations and susceptibility to missing views, particularly during test time. To address these issues, we propose a hybrid, multi-scale and multi-view Swin Transformer-based framework (MSMV-Swin) that enhances diagnostic robustness and accuracy. The proposed MSMV-Swin framework is designed to work as a decision-support tool, helping radiologists analyze multi-view mammograms more effectively. More specifically, the MSMV-Swin framework leverages the Segment Anything Model (SAM) to isolate the breast lobe, reducing background noise and enabling comprehensive feature extraction. The multi-scale nature of the proposed MSMV-Swin framework accounts for tumor-specific regions as well as the spatial characteristics of tissues surrounding the tumor, capturing both localized and contextual information. The integration of contextual and localized data ensures that MSMV-Swin's outputs align with the way radiologists interpret mammograms, fostering better human-AI interaction and trust. A hybrid fusion structure is then designed to ensure robustness against missing views, a common occurrence in clinical practice when only a single mammogram view is available.
Artificial Intelligence-Driven Prognostic Classification of COVID-19 Using Chest X-rays: A Deep Learning Approach
Authors: Alfred Simbun, Suresh Kumar
Date: 2025-03-17 00:00:00
Tasks: Deep Learning, Diagnostic, Prognosis, Specificity

Background: The COVID-19 pandemic has overwhelmed healthcare systems, emphasizing the need for AI-driven tools to assist in rapid and accurate patient prognosis. Chest X-ray imaging is a widely available diagnostic tool, but existing methods for prognosis classification lack scalability and efficiency. Objective: This study presents a high-accuracy deep learning model for classifying COVID-19 severity (Mild, Moderate, and Severe) using Chest X-ray images, developed on Microsoft Azure Custom Vision. Methods: Using a dataset of 1,103 confirmed COVID-19 X-ray images from AIforCOVID, we trained and validated a deep learning model leveraging Convolutional Neural Networks (CNNs). The model was evaluated on an unseen dataset to measure accuracy, precision, and recall. Results: Our model achieved an average accuracy of 97%, with specificity of 99%, sensitivity of 87%, and an F1-score of 93.11%. When classifying COVID-19 severity, the model achieved accuracies of 89.03% (Mild), 95.77% (Moderate), and 81.16% (Severe). These results demonstrate the model's potential for real-world clinical applications, aiding in faster decision-making and improved resource allocation. Conclusion: AI-driven prognosis classification using deep learning can significantly enhance COVID-19 patient management, enabling early intervention and efficient triaging. Our study provides a scalable, high-accuracy AI framework for integrating deep learning into routine clinical workflows. Future work should focus on expanding datasets, external validation, and regulatory compliance to facilitate clinical adoption.
Anatomically and Metabolically Informed Diffusion for Unified Denoising and Segmentation in Low-Count PET Imaging
Authors: Menghua Xia, Kuan-Yin Ko, Der-Shiun Wang, Ming-Kai Chen, Qiong Liu, Huidong Xie, Liang Guo, Wei Ji, Jinsong Ouyang, Reimund Bayerlein, Benjamin A. Spencer, Quanzheng Li, Ramsey D. Badawi, Georges El Fakhri, Chi Liu
Date: 2025-03-17 00:00:00
Tasks: Denoising, Image Denoising, Organ Segmentation

Positron emission tomography (PET) image denoising, along with lesion and organ segmentation, are critical steps in PET-aided diagnosis. However, existing methods typically treat these tasks independently, overlooking inherent synergies between them as correlated steps in the analysis pipeline. In this work, we present the anatomically and metabolically informed diffusion (AMDiff) model, a unified framework for denoising and lesion/organ segmentation in low-count PET imaging. By integrating multi-task functionality and exploiting the mutual benefits of these tasks, AMDiff enables direct quantification of clinical metrics, such as total lesion glycolysis (TLG), from low-count inputs. The AMDiff model incorporates a semantic-informed denoiser based on diffusion strategy and a denoising-informed segmenter utilizing nnMamba architecture. The segmenter constrains denoised outputs via a lesion-organ-specific regularizer, while the denoiser enhances the segmenter by providing enriched image information through a denoising revision module. These components are connected via a warming-up mechanism to optimize multitask interactions. Experiments on multi-vendor, multi-center, and multi-noise-level datasets demonstrate the superior performance of AMDiff. For test cases below 20% of the clinical count levels from participating sites, AMDiff achieves TLG quantification biases of -26.98%, outperforming its ablated versions which yield biases of -35.85% (without the lesion-organ-specific regularizer) and -40.79% (without the denoising revision module).
Sampling Innovation-Based Adaptive Compressive Sensing
Authors: Zhifu Tian, Tao Hu, Chaoyang Niu, Di wu, Shu Wang
Date: 2025-03-17 00:00:00
Proceeding: CVPR 2025 1
Tasks: Compressive Sensing, Image Reconstruction

Scene-aware Adaptive Compressive Sensing (ACS) has attracted significant interest due to its promising capability for efficient and high-fidelity acquisition of scene images. ACS typically prescribes adaptive sampling allocation (ASA) based on previous samples in the absence of ground truth. However, when confronting unknown scenes, existing ACS methods often lack accurate judgment and robust feedback mechanisms for ASA, thus limiting the high-fidelity sensing of the scene. In this paper, we introduce a Sampling Innovation-Based ACS (SIB-ACS) method that can effectively identify and allocate sampling to challenging image reconstruction areas, culminating in high-fidelity image reconstruction. An innovation criterion is proposed to judge ASA by predicting the decrease in image reconstruction error attributable to sampling increments, thereby directing more samples towards regions where the reconstruction error diminishes significantly. A sampling innovation-guided multi-stage adaptive sampling (AS) framework is proposed, which iteratively refines the ASA through a multi-stage feedback process. For image reconstruction, we propose a Principal Component Compressed Domain Network (PCCD-Net), which efficiently and faithfully reconstructs images under AS scenarios. Extensive experiments demonstrate that the proposed SIB-ACS method significantly outperforms the state-of-the-art methods in terms of image reconstruction fidelity and visual effects. Codes are available at https://github.com/giant-pandada/SIB-ACS_CVPR2025.
Logic-in-Frames: Dynamic Keyframe Search via Visual Semantic-Logical Verification for Long Video Understanding
Authors: Weiyu Guo, Ziyang Chen, Shaoguang Wang, Jianxiang He, Yijie Xu, Jinhui Ye, Ying Sun, Hui Xiong
Date: 2025-03-17 00:00:00
Tasks: Attribute, MME, Question Answering, Video MME, Video Question Answering, Video Understanding

Understanding long video content is a complex endeavor that often relies on densely sampled frame captions or end-to-end feature selectors, yet these techniques commonly overlook the logical relationships between textual queries and visual elements. In practice, computational constraints necessitate coarse frame subsampling, a challenge analogous to "finding a needle in a haystack." To address this issue, we introduce a semantics-driven search framework that reformulates keyframe selection under the paradigm of Visual Semantic-Logical Search. Specifically, we systematically define four fundamental logical dependencies: 1) spatial co-occurrence, 2) temporal proximity, 3) attribute dependency, and 4) causal order. These relations dynamically update frame sampling distributions through an iterative refinement process, enabling context-aware identification of semantically critical frames tailored to specific query requirements. Our method establishes new SOTA performance on the manually annotated benchmark in key-frame selection metrics. Furthermore, when applied to downstream video question-answering tasks, the proposed approach demonstrates the best performance gains over existing methods on LongVideoBench and Video-MME, validating its effectiveness in bridging the logical gap between textual queries and visual-temporal reasoning. The code will be publicly available.
OSLO-IC: On-the-Sphere Learned Omnidirectional Image Compression with Attention Modules and Spatial Context
Authors: Paul Wawerek-López, Navid Mahmoudian Bidgoli, Pascal Frossard, André Kaup, Thomas Maugey
Date: 2025-03-17 00:00:00
Tasks: Image Compression

Developing effective 360-degree (spherical) image compression techniques is crucial for technologies like virtual reality and automated driving. This paper advances the state-of-the-art in on-the-sphere learning (OSLO) for omnidirectional image compression framework by proposing spherical attention modules, residual blocks, and a spatial autoregressive context model. These improvements achieve a 23.1% bit rate reduction in terms of WS-PSNR BD rate. Additionally, we introduce a spherical transposed convolution operator for upsampling, which reduces trainable parameters by a factor of four compared to the pixel shuffling used in the OSLO framework, while maintaining similar compression performance. Therefore, in total, our proposed method offers significant rate savings with a smaller architecture and can be applied to any spherical convolutional application.
DehazeMamba: SAR-guided Optical Remote Sensing Image Dehazing with Adaptive State Space Model
Authors: Zhicheng Zhao, Jinquan Yan, Chenglong Li, Xiao Wang, Jin Tang
Date: 2025-03-17 00:00:00
Tasks: Image Dehazing, Semantic Segmentation, Single Image Dehazing

Optical remote sensing image dehazing presents significant challenges due to its extensive spatial scale and highly non-uniform haze distribution, which traditional single-image dehazing methods struggle to address effectively. While Synthetic Aperture Radar (SAR) imagery offers inherently haze-free reference information for large-scale scenes, existing SAR-guided dehazing approaches face two critical limitations: the integration of SAR information often diminishes the quality of haze-free regions, and the instability of feature quality further exacerbates cross-modal domain shift. To overcome these challenges, we introduce DehazeMamba, a novel SAR-guided dehazing network built on a progressive haze decoupling fusion strategy. Our approach incorporates two key innovations: a Haze Perception and Decoupling Module (HPDM) that dynamically identifies haze-affected regions through optical-SAR difference analysis, and a Progressive Fusion Module (PFM) that mitigates domain shift through a two-stage fusion process based on feature quality assessment. To facilitate research in this domain, we present MRSHaze, a large-scale benchmark dataset comprising 8,000 pairs of temporally synchronized, precisely geo-registered SAR-optical images with high resolution and diverse haze conditions. Extensive experiments demonstrate that DehazeMamba significantly outperforms state-of-the-art methods, achieving a 0.73 dB improvement in PSNR and substantial enhancements in downstream tasks such as semantic segmentation. The dataset is available at https://github.com/mmic-lcl/Datasets-and-benchmark-code.
How Good is my Histopathology Vision-Language Foundation Model? A Holistic Benchmark
Authors: Roba Al Majzoub, Hashmat Malik, Muzammal Naseer, Zaigham Zaheer, Tariq Mahmood, Salman Khan, Fahad Khan
Date: 2025-03-17 00:00:00

Recently, histopathology vision-language foundation models (VLMs) have gained popularity due to their enhanced performance and generalizability across different downstream tasks. However, most existing histopathology benchmarks are either unimodal or limited in terms of diversity of clinical tasks, organs, and acquisition instruments, as well as their partial availability to the public due to patient data privacy. As a consequence, there is a lack of comprehensive evaluation of existing histopathology VLMs on a unified benchmark setting that better reflects a wide range of clinical scenarios. To address this gap, we introduce HistoVL, a fully open-source comprehensive benchmark comprising images acquired using up to 11 various acquisition tools that are paired with specifically crafted captions by incorporating class names and diverse pathology descriptions. Our Histo-VL includes 26 organs, 31 cancer types, and a wide variety of tissue obtained from 14 heterogeneous patient cohorts, totaling more than 5 million patches obtained from over 41K WSIs viewed under various magnification levels. We systematically evaluate existing histopathology VLMs on Histo-VL to simulate diverse tasks performed by experts in real-world clinical scenarios. Our analysis reveals interesting findings, including large sensitivity of most existing histopathology VLMs to textual changes with a drop in balanced accuracy of up to 25% in tasks such as Metastasis detection, low robustness to adversarial attacks, as well as improper calibration of models evident through high ECE values and low model prediction confidence, all of which can affect their clinical implementation.
MSWAL: 3D Multi-class Segmentation of Whole Abdominal Lesions Dataset
Authors: Zhaodong Wu, Qiaochu Zhao, Ming Hu, Yulong Li, Haochen Xue, Kang Dang, Zhengyong Jiang, Angelos Stefanidis, Qiufeng Wang, Imran Razzak, ZongYuan Ge, Junjun He, Yu Qiao, Zhong Zheng, Feilong Tang, Jionglong Su
Date: 2025-03-17 00:00:00
Tasks: Transfer Learning

With the significantly increasing incidence and prevalence of abdominal diseases, there is a need to embrace greater use of new innovations and technology for the diagnosis and treatment of patients. Although deep-learning methods have notably been developed to assist radiologists in diagnosing abdominal diseases, existing models have the restricted ability to segment common lesions in the abdomen due to missing annotations for typical abdominal pathologies in their training datasets. To address the limitation, we introduce MSWAL, the first 3D Multi-class Segmentation of the Whole Abdominal Lesions dataset, which broadens the coverage of various common lesion types, such as gallstones, kidney stones, liver tumors, kidney tumors, pancreatic cancer, liver cysts, and kidney cysts. With CT scans collected from 694 patients (191,417 slices) of different genders across various scanning phases, MSWAL demonstrates strong robustness and generalizability. The transfer learning experiment from MSWAL to two public datasets, LiTS and KiTS, effectively demonstrates consistent improvements, with Dice Similarity Coefficient (DSC) increase of 3.00% for liver tumors and 0.89% for kidney tumors, demonstrating that the comprehensive annotations and diverse lesion types in MSWAL facilitate effective learning across different domains and data distributions. Furthermore, we propose Inception nnU-Net, a novel segmentation framework that effectively integrates an Inception module with the nnU-Net architecture to extract information from different receptive fields, achieving significant enhancement in both voxel-level DSC and region-level F1 compared to the cutting-edge public algorithms on MSWAL. Our dataset will be released after being accepted, and the code is publicly released at https://github.com/tiuxuxsh76075/MSWAL-.
Mixed-granularity Implicit Representation for Continuous Hyperspectral Compressive Reconstruction
Authors: Jianan Li, Huan Chen, Wangcai Zhao, Rui Chen, Tingfa Xu
Date: 2025-03-17 00:00:00
Tasks: Decoder, Image Reconstruction

Hyperspectral Images (HSIs) are crucial across numerous fields but are hindered by the long acquisition times associated with traditional spectrometers. The Coded Aperture Snapshot Spectral Imaging (CASSI) system mitigates this issue through a compression technique that accelerates the acquisition process. However, reconstructing HSIs from compressed data presents challenges due to fixed spatial and spectral resolution constraints. This study introduces a novel method using implicit neural representation for continuous hyperspectral image reconstruction. We propose the Mixed Granularity Implicit Representation (MGIR) framework, which includes a Hierarchical Spectral-Spatial Implicit Encoder for efficient multi-scale implicit feature extraction. This is complemented by a Mixed-Granularity Local Feature Aggregator that adaptively integrates local features across scales, combined with a decoder that merges coordinate information for precise reconstruction. By leveraging implicit neural representations, the MGIR framework enables reconstruction at any desired spatial-spectral resolution, significantly enhancing the flexibility and adaptability of the CASSI system. Extensive experimental evaluations confirm that our model produces reconstructed images at arbitrary resolutions and matches state-of-the-art methods across varying spectral-spatial compression ratios. The code will be released at https://github.com/chh11/MGIR.