pwc-archive/papers-with-abstracts huggingface dataset:
UnPuzzle: A Unified Framework for Pathology Image Analysis
Authors: Dankai Liao, Sicheng Chen, Nuwa Xi, Qiaochu Xue, Jieyu Li, Lingxuan Hou, Zeyu Liu, Chang Han Low, Yufeng Wu, Yiling Liu, Yanqin Jiang, Dandan Li, Shangqing Lyu
Date: 2025-03-05 00:00:00
Tasks: Benchmarking, Diagnostic, Medical Diagnosis, Multi-Task Learning, whole slide images

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks, the lack of standardization in pre-processing methods and model/database architectures complicates fair comparisons across different approaches. This highlights the need for a unified pipeline and comprehensive benchmarks to enable consistent evaluation and accelerate research progress. In this paper, we present UnPuzzle, a novel and unified framework for pathological AI research that covers a broad range of pathology tasks with benchmark results. From high-level to low-level, upstream to downstream tasks, UnPuzzle offers a modular pipeline that encompasses data pre-processing, model composition,taskconfiguration,andexperimentconduction.Specifically, it facilitates efficient benchmarking for both Whole Slide Images (WSIs) and Region of Interest (ROI) tasks. Moreover, the framework supports variouslearningparadigms,includingself-supervisedlearning,multi-task learning,andmulti-modallearning,enablingcomprehensivedevelopment of pathology AI models. Through extensive benchmarking across multiple datasets, we demonstrate the effectiveness of UnPuzzle in streamlining pathology AI research and promoting reproducibility. We envision UnPuzzle as a cornerstone for future advancements in pathology AI, providing a more accessible, transparent, and standardized approach to model evaluation. The UnPuzzle repository is publicly available at https://github.com/Puzzle-AI/UnPuzzle.
Implicit U-KAN2.0: Dynamic, Efficient and Interpretable Medical Image Segmentation
Authors: Chun-Wun Cheng, Yining Zhao, Yanqi Cheng, Javier Montoya, Carola-Bibiane Schönlieb, Angelica I Aviles-Rivero
Date: 2025-03-05 00:00:00
Tasks: Decoder, Image Segmentation, Medical Image Segmentation, Semantic Segmentation

Image segmentation is a fundamental task in both image analysis and medical applications. State-of-the-art methods predominantly rely on encoder-decoder architectures with a U-shaped design, commonly referred to as U-Net. Recent advancements integrating transformers and MLPs improve performance but still face key limitations, such as poor interpretability, difficulty handling intrinsic noise, and constrained expressiveness due to discrete layer structures, often lacking a solid theoretical foundation.In this work, we introduce Implicit U-KAN 2.0, a novel U-Net variant that adopts a two-phase encoder-decoder structure. In the SONO phase, we use a second-order neural ordinary differential equation (NODEs), called the SONO block, for a more efficient, expressive, and theoretically grounded modeling approach. In the SONO-MultiKAN phase, we integrate the second-order NODEs and MultiKAN layer as the core computational block to enhance interpretability and representation power. Our contributions are threefold. First, U-KAN 2.0 is an implicit deep neural network incorporating MultiKAN and second order NODEs, improving interpretability and performance while reducing computational costs. Second, we provide a theoretical analysis demonstrating that the approximation ability of the MultiKAN block is independent of the input dimension. Third, we conduct extensive experiments on a variety of 2D and a single 3D dataset, demonstrating that our model consistently outperforms existing segmentation networks.
SPIDER: A Comprehensive Multi-Organ Supervised Pathology Dataset and Baseline Models
Authors: Dmitry Nechaev, Alexey Pchelnikov, Ekaterina Ivanova
Date: 2025-03-04 00:00:00
Tasks: Image Description

Advancing AI in computational pathology requires large, high-quality, and diverse datasets, yet existing public datasets are often limited in organ diversity, class coverage, or annotation quality. To bridge this gap, we introduce SPIDER (Supervised Pathology Image-DEscription Repository), the largest publicly available patch-level dataset covering multiple organ types, including Skin, Colorectal, Thorax, and Breast with comprehensive class coverage for each organ. SPIDER provides high-quality annotations verified by expert pathologists and includes surrounding context patches, which enhance classification performance by providing spatial context. Alongside the dataset, we present baseline models trained on SPIDER using the Hibou-L foundation model as a feature extractor combined with an attention-based classification head. The models achieve state-of-the-art performance across multiple tissue categories and serve as strong benchmarks for future digital pathology research. Beyond patch classification, the model enables rapid identification of significant areas, quantitative tissue metrics, and establishes a foundation for multimodal approaches. Both the dataset and trained models are publicly available to advance research, reproducibility, and AI-driven pathology development. Access them at: https://github.com/HistAI/SPIDER
Undertrained Image Reconstruction for Realistic Degradation in Blind Image Super-Resolution
Authors: Ru Ito, Supatta Viriyavisuthisakul, Kazuhiko Kawamoto, Hiroshi Kera
Date: 2025-03-04 00:00:00
Tasks: Dataset Generation, Image Reconstruction, Image Super-Resolution, Super-Resolution

Most super-resolution (SR) models struggle with real-world low-resolution (LR) images. This issue arises because the degradation characteristics in the synthetic datasets differ from those in real-world LR images. Since SR models are trained on pairs of high-resolution (HR) and LR images generated by downsampling, they are optimized for simple degradation. However, real-world LR images contain complex degradation caused by factors such as the imaging process and JPEG compression. Due to these differences in degradation characteristics, most SR models perform poorly on real-world LR images. This study proposes a dataset generation method using undertrained image reconstruction models. These models have the property of reconstructing low-quality images with diverse degradation from input images. By leveraging this property, this study generates LR images with diverse degradation from HR images to construct the datasets. Fine-tuning pre-trained SR models on our generated datasets improves noise removal and blur reduction, enhancing performance on real-world LR images. Furthermore, an analysis of the datasets reveals that degradation diversity contributes to performance improvements, whereas color differences between HR and LR images may degrade performance. 11 pages, (11 figures and 2 tables)
A Joint Visual Compression and Perception Framework for Neuralmorphic Spiking Camera
Authors: Kexiang Feng, Chuanmin Jia, Siwei Ma, Wen Gao
Date: 2025-03-04 00:00:00
Tasks: Attribute

The advent of neuralmorphic spike cameras has garnered significant attention for their ability to capture continuous motion with unparalleled temporal resolution.However, this imaging attribute necessitates considerable resources for binary spike data storage and transmission.In light of compression and spike-driven intelligent applications, we present the notion of Spike Coding for Intelligence (SCI), wherein spike sequences are compressed and optimized for both bit-rate and task performance.Drawing inspiration from the mammalian vision system, we propose a dual-pathway architecture for separate processing of spatial semantics and motion information, which is then merged to produce features for compression.A refinement scheme is also introduced to ensure consistency between decoded features and motion vectors.We further propose a temporal regression approach that integrates various motion dynamics, capitalizing on the advancements in warping and deformation simultaneously.Comprehensive experiments demonstrate our scheme achieves state-of-the-art (SOTA) performance for spike compression and analysis.We achieve an average 17.25% BD-rate reduction compared to SOTA codecs and a 4.3% accuracy improvement over SpiReco for spike-based classification, with 88.26% complexity reduction and 42.41% inference time saving on the encoding side.
Interpretable Few-Shot Retinal Disease Diagnosis with Concept-Guided Prompting of Vision-Language Models
Authors: Deval Mehta, Yiwen Jiang, Catherine L Jan, Mingguang He, Kshitij Jadhav, ZongYuan Ge
Date: 2025-03-04 00:00:00
Tasks: Diagnostic, Prompt Learning

Recent advancements in deep learning have shown significant potential for classifying retinal diseases using color fundus images. However, existing works predominantly rely exclusively on image data, lack interpretability in their diagnostic decisions, and treat medical professionals primarily as annotators for ground truth labeling. To fill this gap, we implement two key strategies: extracting interpretable concepts of retinal diseases using the knowledge base of GPT models and incorporating these concepts as a language component in prompt-learning to train vision-language (VL) models with both fundus images and their associated concepts. Our method not only improves retinal disease classification but also enriches few-shot and zero-shot detection (novel disease detection), while offering the added benefit of concept-based model interpretability. Our extensive evaluation across two diverse retinal fundus image datasets illustrates substantial performance gains in VL-model based few-shot methodologies through our concept integration approach, demonstrating an average improvement of approximately 5.8\% and 2.7\% mean average precision for 16-shot learning and zero-shot (novel class) detection respectively. Our method marks a pivotal step towards interpretable and efficient retinal disease recognition for real-world clinical applications.
Q&C: When Quantization Meets Cache in Efficient Image Generation
Authors: Xin Ding, Xin Li, Haotong Qin, Zhibo Chen
Date: 2025-03-04 00:00:00
Tasks: Image Generation, Quantization

Quantization and cache mechanisms are typically applied individually for efficient Diffusion Transformers (DiTs), each demonstrating notable potential for acceleration. However, the promoting effect of combining the two mechanisms on efficient generation remains under-explored. Through empirical investigation, we find that the combination of quantization and cache mechanisms for DiT is not straightforward, and two key challenges lead to severe catastrophic performance degradation: (i) the sample efficacy of calibration datasets in post-training quantization (PTQ) is significantly eliminated by cache operation; (ii) the combination of the above mechanisms introduces more severe exposure bias within sampling distribution, resulting in amplified error accumulation in the image generation process. In this work, we take advantage of these two acceleration mechanisms and propose a hybrid acceleration method by tackling the above challenges, aiming to further improve the efficiency of DiTs while maintaining excellent generation capability. Concretely, a temporal-aware parallel clustering (TAP) is designed to dynamically improve the sample selection efficacy for the calibration within PTQ for different diffusion steps. A variance compensation (VC) strategy is derived to correct the sampling distribution. It mitigates exposure bias through an adaptive correction factor generation. Extensive experiments have shown that our method has accelerated DiTs by 12.7x while preserving competitive generation capability. The code will be available at https://github.com/xinding-sys/Quant-Cache.
Building 3D In-Context Learning Universal Model in Neuroimaging
Authors: Jiesi Hu, Hanyang Peng, Yanwu Yang, Xutao Guo, Yang Shang, Pengcheng Shi, Chenfei Ye, Ting Ma
Date: 2025-03-04 00:00:00
Tasks: Denoising, In-Context Learning

In-context learning (ICL), a type of universal model, demonstrates exceptional generalization across a wide range of tasks without retraining by leveraging task-specific guidance from context, making it particularly effective for the complex demands of neuroimaging. However, existing ICL models, which take 2D images as input, struggle to fully leverage the 3D anatomical structures in neuroimages, leading to a lack of global awareness and suboptimal performance. In this regard, we introduce Neuroverse3D, an ICL model capable of performing multiple neuroimaging tasks (e.g., segmentation, denoising, inpainting) in 3D. Neuroverse3D overcomes the large memory consumption due to 3D inputs through adaptive parallel-sequential context processing and a U-shape fusion strategy, allowing it to handle an unlimited number of context images. Additionally, we propose an optimized loss to balance multi-task training and enhance the focus on anatomical structures. Our study incorporates 43,674 3D scans from 19 neuroimaging datasets and evaluates Neuroverse3D on 14 diverse tasks using held-out test sets. The results demonstrate that Neuroverse3D significantly outperforms existing ICL models and closely matches the performance of task-specific models. The code and model weights are publicly released at: https://github.com/jiesihu/Neu3D.
COMMA: Coordinate-aware Modulated Mamba Network for 3D Dispersed Vessel Segmentation
Authors: Gen Shi, HUI ZHANG, Jie Tian
Date: 2025-03-04 00:00:00
Tasks: Computational Efficiency, Mamba

Accurate segmentation of 3D vascular structures is essential for various medical imaging applications. The dispersed nature of vascular structures leads to inherent spatial uncertainty and necessitates location awareness, yet most current 3D medical segmentation models rely on the patch-wise training strategy that usually loses this spatial context. In this study, we introduce the Coordinate-aware Modulated Mamba Network (COMMA) and contribute a manually labeled dataset of 570 cases, the largest publicly available 3D vessel dataset to date. COMMA leverages both entire and cropped patch data through global and local branches, ensuring robust and efficient spatial location awareness. Specifically, COMMA employs a channel-compressed Mamba (ccMamba) block to encode entire image data, capturing long-range dependencies while optimizing computational costs. Additionally, we propose a coordinate-aware modulated (CaM) block to enhance interactions between the global and local branches, allowing the local branch to better perceive spatial information. We evaluate COMMA on six datasets, covering two imaging modalities and five types of vascular tissues. The results demonstrate COMMA's superior performance compared to state-of-the-art methods with computational efficiency, especially in segmenting small vessels. Ablation studies further highlight the importance of our proposed modules and spatial information. The code and data will be open source at https://github.com/shigen-StoneRoot/COMMA.
Generative Model-Assisted Demosaicing for Cross-multispectral Cameras
Authors: Jiahui Luo, Kai Feng, Haijin Zeng, Yongyong Chen
Date: 2025-03-04 00:00:00
Tasks: Demosaicking

As a crucial part of the spectral filter array (SFA)-based multispectral imaging process, spectral demosaicing has exploded with the proliferation of deep learning techniques. However, (1) bothering by the difficulty of capturing corresponding labels for real data or simulating the practical spectral imaging process, end-to-end networks trained in a supervised manner using simulated data often perform poorly on real data. (2) cross-camera spectral discrepancies make it difficult to apply pre-trained models to new cameras. (3) existing demosaicing networks are prone to introducing visual artifacts on hard cases due to the interpolation of unknown values. To address these issues, we propose a hybrid supervised training method with the assistance of the self-supervised generative model, which performs well on real data across different spectral cameras. Specifically, our approach consists of three steps: (1) Pre-Training step: training the end-to-end neural network on a large amount of simulated data; (2) Pseudo-Pairing step: generating pseudo-labels of real target data using the self-supervised generative model; (3) Fine-Tuning step: fine-tuning the pre-trained model on the pseudo data pairs obtained in (2). To alleviate artifacts, we propose a frequency-domain hard patch selection method that identifies artifact-prone regions by analyzing spectral discrepancies using Fourier transform and filtering techniques, allowing targeted fine-tuning to enhance demosaicing performance. Finally, we propose UniSpecTest, a real-world multispectral mosaic image dataset for testing. Ablation experiments have demonstrated the effectiveness of each training step, and extensive experiments on both synthetic and real datasets show that our method achieves significant performance gains compared to state-of-the-art techniques.
Rapid Bone Scintigraphy Enhancement via Semantic Prior Distillation from Segment Anything Model
Authors: Pengchen Liang, Leijun Shi, Huiping Yao, Bin Pu, Jianguo Chen, Lei Zhao, Haishan Huang, Zhuangzhuang Chen, Zhaozhao Xu, Lite Xu, Qing Chang, Yiwei Li
Date: 2025-03-04 00:00:00
Tasks: Image Restoration, Knowledge Distillation, SSIM

Rapid bone scintigraphy is crucial for diagnosing skeletal disorders and detecting tumor metastases in children, as it shortens scan duration and reduces discomfort. However, accelerated acquisition often degrades image quality, impairing the visibility of fine anatomical details and potentially compromising diagnosis. To overcome this limitation, we introduce the first application of SAM-based semantic priors for medical image restoration, utilizing the Segment Anything Model (SAM) to enhance pediatric rapid bone scintigraphy. Our approach employs two cascaded networks, $f^{IR1}$ and $f^{IR2}$, supported by three specialized modules: a Semantic Prior Integration (SPI) module, a Semantic Knowledge Distillation (SKD) module, and a Semantic Consistency Module (SCM). The SPI and SKD modules inject domain-specific semantic cues from a fine-tuned SAM, while the SCM preserves coherent semantic feature representations across both cascaded stages. Moreover, we present RBS, a novel Rapid Bone Scintigraphy dataset comprising paired standard (20 cm/min) and rapid (40 cm/min) scans from 137 pediatric patients aged 0.5 - 16 years, making it the first dataset tailored for pediatric rapid bone scintigraphy restoration. Extensive experiments on both a public endoscopic dataset and our RBS dataset demonstrate that our method consistently surpasses existing techniques in PSNR, SSIM, FID, and LPIPS metrics.
Volume Tells: Dual Cycle-Consistent Diffusion for 3D Fluorescence Microscopy De-noising and Super-Resolution
Authors: Zelin Li, Chenwei Wang, Zhaoke Huang, Yiming Ma, Cunmin Zhao, Zhongying Zhao, Hong Yan
Date: 2025-03-04 00:00:00
Proceeding: CVPR 2025 1
Tasks: Denoising, Super-Resolution

3D fluorescence microscopy is essential for understanding fundamental life processes through long-term live-cell imaging. However, due to inherent issues in imaging principles, it faces significant challenges including spatially varying noise and anisotropic resolution, where the axial resolution lags behind the lateral resolution up to 4.5 times. Meanwhile, laser power is kept low to maintain cell viability, leading to inaccessible low-noise and high-resolution paired ground truth (GT). To tackle these limitations, a dual Cycle-consistent Diffusion is proposed to effectively mine intra-volume imaging priors within 3D cell volumes in an unsupervised manner, i.e., Volume Tells (VTCD), achieving de-noising and super-resolution (SR) simultaneously. Specifically, a spatially iso-distributed denoiser is designed to exploit the noise distribution consistency between adjacent low-noise and high-noise regions within the 3D cell volume, suppressing the spatially varying noise. Then, in light of the structural consistency of the cell volume, a cross-plane global-propagation SR module propagates high-resolution details from the XY plane into adjacent regions in the XZ and YZ planes, progressively enhancing resolution across the entire 3D cell volume. Experimental results on 10 in vivo cellular dataset demonstrate high improvements in both denoising and super-resolution, with axial resolution enhanced from ~ 430 nm to ~ 90 nm.
$\mathbfΦ$-GAN: Physics-Inspired GAN for Generating SAR Images Under Limited Data
Authors: Xidan Zhang, Yihan Zhuang, Qian Guo, Haodong Yang, Xuelin Qian, Gong Cheng, Junwei Han, Zhongling Huang
Date: 2025-03-04 00:00:00

Approaches for improving generative adversarial networks (GANs) training under a few samples have been explored for natural images. However, these methods have limited effectiveness for synthetic aperture radar (SAR) images, as they do not account for the unique electromagnetic scattering properties of SAR. To remedy this, we propose a physics-inspired regularization method dubbed $\Phi$-GAN, which incorporates the ideal point scattering center (PSC) model of SAR with two physical consistency losses. The PSC model approximates SAR targets using physical parameters, ensuring that $\Phi$-GAN generates SAR images consistent with real physical properties while preventing discriminator overfitting by focusing on PSC-based decision cues. To embed the PSC model into GANs for end-to-end training, we introduce a physics-inspired neural module capable of estimating the physical parameters of SAR targets efficiently. This module retains the interpretability of the physical model and can be trained with limited data. We propose two physical loss functions: one for the generator, guiding it to produce SAR images with physical parameters consistent with real ones, and one for the discriminator, enhancing its robustness by basing decisions on PSC attributes. We evaluate $\Phi$-GAN across several conditional GAN (cGAN) models, demonstrating state-of-the-art performance in data-scarce scenarios on three SAR image datasets.
Anomaly detection in non-stationary videos using time-recursive differencing network based prediction
Authors: Gargi V. Pillai, Debashis Sen
Date: 2025-03-04 00:00:00
Tasks: Anomaly Detection, Optical Flow Estimation, Prediction, Video Anomaly Detection

Most videos, including those captured through aerial remote sensing, are usually non-stationary in nature having time-varying feature statistics. Although, sophisticated reconstruction and prediction models exist for video anomaly detection, effective handling of non-stationarity has seldom been considered explicitly. In this paper, we propose to perform prediction using a time-recursive differencing network followed by autoregressive moving average estimation for video anomaly detection. The differencing network is employed to effectively handle non-stationarity in video data during the anomaly detection. Focusing on the prediction process, the effectiveness of the proposed approach is demonstrated considering a simple optical flow based video feature, and by generating qualitative and quantitative results on three aerial video datasets and two standard anomaly detection video datasets. EER, AUC and ROC curve based comparison with several existing methods including the state-of-the-art reveal the superiority of the proposed approach.