pwc-archive/papers-with-abstracts huggingface dataset:
Volumetric segmentation of muscle compartments using in vivo imaging and architectural validation in human finger flexors
Authors: Yang Li
Date: 2025-06-25 00:00:00
Tasks: Anatomy, Segmentation

Segmenting muscle compartments and measuring their architecture can facilitate movement function assessment, accurate musculoskeletal modeling, and synergy-based electromyogram simulation. Here, we presented a novel method for volumetric segmentation of muscle compartments using in vivo imaging, focusing on the independent compartments for finger control of flexor digitorum superficialis (FDS). Besides, we measured the architectural properties of FDS compartments and validated the segmentation. Specifically, ultrasound and magnetic resonance imaging (MRI) from 10 healthy subjects were used for segmentation and measurement, while electromyography was utilized for validation. A two-step piecewise segmentation was proposed, first annotating compartment regions in the cross-sectional ultrasound image based on compartment movement, and then performing minimum energy matching to register the ultrasound data to the three-dimensional MRI coordinate system. Additionally, the architectural properties were measured in the compartment masks from the segmentation using MRI tractography. Anatomical correctness was verified by comparing known anatomy with reconstructed fiber tracts and measured properties, while segmentation accuracy was quantified as the percentage of finger electromyogram centers falling within their corresponding compartments. Results demonstrated agreement for the fiber orientation between the tractography and cadaveric photographs. Significant differences in architectural properties (P < 0.001) were observed between compartments. The properties of FDS and its compartments were within the physiological ranges (P < 0.01). 95% (38/40) of the electromyogram centers were located within respective compartments, with 2 errors occurring in the index and little fingers. The validated segmentation method and derived architectural properties may advance biomedical applications.
U-R-VEDA: Integrating UNET, Residual Links, Edge and Dual Attention, and Vision Transformer for Accurate Semantic Segmentation of CMRs
Authors: Racheal Mukisa, Arvind K. Bansal
Date: 2025-06-25 00:00:00
Tasks: Edge Detection, Medical Image Analysis, Semantic Segmentation

Artificial intelligence, including deep learning models, will play a transformative role in automated medical image analysis for the diagnosis of cardiac disorders and their management. Automated accurate delineation of cardiac images is the first necessary initial step for the quantification and automated diagnosis of cardiac disorders. In this paper, we propose a deep learning based enhanced UNet model, U-R-Veda, which integrates convolution transformations, vision transformer, residual links, channel-attention, and spatial attention, together with edge-detection based skip-connections for an accurate fully-automated semantic segmentation of cardiac magnetic resonance (CMR) images. The model extracts local-features and their interrelationships using a stack of combination convolution blocks, with embedded channel and spatial attention in the convolution block, and vision transformers. Deep embedding of channel and spatial attention in the convolution block identifies important features and their spatial localization. The combined edge information with channel and spatial attention as skip connection reduces information-loss during convolution transformations. The overall model significantly improves the semantic segmentation of CMR images necessary for improved medical image analysis. An algorithm for the dual attention module (channel and spatial attention) has been presented. Performance results show that U-R-Veda achieves an average accuracy of 95.2%, based on DSC metrics. The model outperforms the accuracy attained by other models, based on DSC and HD metrics, especially for the delineation of right-ventricle and left-ventricle-myocardium.
Building Lightweight Semantic Segmentation Models for Aerial Images Using Dual Relation Distillation
Authors: Minglong Li, Lianlei Shan, Weiqiang Wang, Ke Lv, Bin Luo, Si-Bao Chen
Date: 2025-06-25 00:00:00
Tasks: Knowledge Distillation, Relation, Segmentation, Semantic Segmentation

Recently, there have been significant improvements in the accuracy of CNN models for semantic segmentation. However, these models are often heavy and suffer from low inference speed, which limits their practical application. To address this issue, knowledge distillation has emerged as a promising approach to achieve a good trade-off between segmentation accuracy and efficiency. In this paper, we propose a novel dual relation distillation (DRD) technique that transfers both spatial and channel relations in feature maps from a cumbersome model (teacher) to a compact model (student). Specifically, we compute spatial and channel relation maps separately for the teacher and student models, and then align corresponding relation maps by minimizing their distance. Since the teacher model usually learns more information and collects richer spatial and channel correlations than the student model, transferring these correlations from the teacher to the student can help the student mimic the teacher better in terms of feature distribution, thus improving the segmentation accuracy of the student model. We conduct comprehensive experiments on three segmentation datasets, including two widely adopted benchmarks in the remote sensing field (Vaihingen and Potsdam datasets) and one popular benchmark in general scene (Cityscapes dataset). The experimental results demonstrate that our novel distillation framework can significantly boost the performance of the student network without incurring extra computational overhead.
Global and Local Contrastive Learning for Joint Representations from Cardiac MRI and ECG
Authors: Alexander Selivanov, Philip Müller, Özgün Turgut, Nil Stolt-Ansó, Daniel Rückert
Date: 2025-06-24 00:00:00
Tasks: Contrastive Learning, Diagnostic

An electrocardiogram (ECG) is a widely used, cost-effective tool for detecting electrical abnormalities in the heart. However, it cannot directly measure functional parameters, such as ventricular volumes and ejection fraction, which are crucial for assessing cardiac function. Cardiac magnetic resonance (CMR) is the gold standard for these measurements, providing detailed structural and functional insights, but is expensive and less accessible. To bridge this gap, we propose PTACL (Patient and Temporal Alignment Contrastive Learning), a multimodal contrastive learning framework that enhances ECG representations by integrating spatio-temporal information from CMR. PTACL uses global patient-level contrastive loss and local temporal-level contrastive loss. The global loss aligns patient-level representations by pulling ECG and CMR embeddings from the same patient closer together, while pushing apart embeddings from different patients. Local loss enforces fine-grained temporal alignment within each patient by contrasting encoded ECG segments with corresponding encoded CMR frames. This approach enriches ECG representations with diagnostic information beyond electrical activity and transfers more insights between modalities than global alignment alone, all without introducing new learnable weights. We evaluate PTACL on paired ECG-CMR data from 27,951 subjects in the UK Biobank. Compared to baseline approaches, PTACL achieves better performance in two clinically relevant tasks: (1) retrieving patients with similar cardiac phenotypes and (2) predicting CMR-derived cardiac function parameters, such as ventricular volumes and ejection fraction. Our results highlight the potential of PTACL to enhance non-invasive cardiac diagnostics using ECG. The code is available at: https://github.com/alsalivan/ecgcmr
Systematic Review of Pituitary Gland and Pituitary Adenoma Automatic Segmentation Techniques in Magnetic Resonance Imaging
Authors: Mubaraq Yakubu, Navodini Wijethilake, Jonathan Shapey, Andrew King, Alexander Hammers
Date: 2025-06-24 00:00:00
Tasks: Segmentation

Purpose: Accurate segmentation of both the pituitary gland and adenomas from magnetic resonance imaging (MRI) is essential for diagnosis and treatment of pituitary adenomas. This systematic review evaluates automatic segmentation methods for improving the accuracy and efficiency of MRI-based segmentation of pituitary adenomas and the gland itself. Methods: We reviewed 34 studies that employed automatic and semi-automatic segmentation methods. We extracted and synthesized data on segmentation techniques and performance metrics (such as Dice overlap scores). Results: The majority of reviewed studies utilized deep learning approaches, with U-Net-based models being the most prevalent. Automatic methods yielded Dice scores of 0.19--89.00\% for pituitary gland and 4.60--96.41\% for adenoma segmentation. Semi-automatic methods reported 80.00--92.10\% for pituitary gland and 75.90--88.36\% for adenoma segmentation. Conclusion: Most studies did not report important metrics such as MR field strength, age and adenoma size. Automated segmentation techniques such as U-Net-based models show promise, especially for adenoma segmentation, but further improvements are needed to achieve consistently good performance in small structures like the normal pituitary gland. Continued innovation and larger, diverse datasets are likely critical to enhancing clinical applicability.
NeRF-based CBCT Reconstruction needs Normalization and Initialization
Authors: Zhuowei Xu, Han Li, Dai Sun, Zhicheng Li, Yujia Li, Qingpeng Kong, Zhiwei Cheng, Nassir Navab, S. Kevin Zhou
Date: 2025-06-24 00:00:00
Tasks: global-optimization, NeRF

Cone Beam Computed Tomography (CBCT) is widely used in medical imaging. However, the limited number and intensity of X-ray projections make reconstruction an ill-posed problem with severe artifacts. NeRF-based methods have achieved great success in this task. However, they suffer from a local-global training mismatch between their two key components: the hash encoder and the neural network. Specifically, in each training step, only a subset of the hash encoder's parameters is used (local sparse), whereas all parameters in the neural network participate (global dense). Consequently, hash features generated in each step are highly misaligned, as they come from different subsets of the hash encoder. These misalignments from different training steps are then fed into the neural network, causing repeated inconsistent global updates in training, which leads to unstable training, slower convergence, and degraded reconstruction quality. Aiming to alleviate the impact of this local-global optimization mismatch, we introduce a Normalized Hash Encoder, which enhances feature consistency and mitigates the mismatch. Additionally, we propose a Mapping Consistency Initialization(MCI) strategy that initializes the neural network before training by leveraging the global mapping property from a well-trained model. The initialized neural network exhibits improved stability during early training, enabling faster convergence and enhanced reconstruction performance. Our method is simple yet effective, requiring only a few lines of code while substantially improving training efficiency on 128 CT cases collected from 4 different datasets, covering 7 distinct anatomical regions.
ReCoGNet: Recurrent Context-Guided Network for 3D MRI Prostate Segmentation
Authors: Ahmad Mustafa, Reza Rastegar, Ghassan AlRegib
Date: 2025-06-24 00:00:00
Tasks: Segmentation

Prostate gland segmentation from T2-weighted MRI is a critical yet challenging task in clinical prostate cancer assessment. While deep learning-based methods have significantly advanced automated segmentation, most conventional approaches-particularly 2D convolutional neural networks (CNNs)-fail to leverage inter-slice anatomical continuity, limiting their accuracy and robustness. Fully 3D models offer improved spatial coherence but require large amounts of annotated data, which is often impractical in clinical settings. To address these limitations, we propose a hybrid architecture that models MRI sequences as spatiotemporal data. Our method uses a deep, pretrained DeepLabV3 backbone to extract high-level semantic features from each MRI slice and a recurrent convolutional head, built with ConvLSTM layers, to integrate information across slices while preserving spatial structure. This combination enables context-aware segmentation with improved consistency, particularly in data-limited and noisy imaging conditions. We evaluate our method on the PROMISE12 benchmark under both clean and contrast-degraded test settings. Compared to state-of-the-art 2D and 3D segmentation models, our approach demonstrates superior performance in terms of precision, recall, Intersection over Union (IoU), and Dice Similarity Coefficient (DSC), highlighting its potential for robust clinical deployment.
crossMoDA Challenge: Evolution of Cross-Modality Domain Adaptation Techniques for Vestibular Schwannoma and Cochlea Segmentation from 2021 to 2023
Authors: Navodini Wijethilake, Reuben Dorent, Marina Ivory, Aaron Kujawa, Stefan Cornelissen, Patrick Langenhuizen, Mohamed Okasha, Anna Oviedova, Hexin Dong, Bogyeong Kang, Guillaume Sallé, Luyi Han, Ziyuan Zhao, Han Liu, Tao Yang, Shahad Hardan, Hussain Alasmawi, Santosh Sanjeev, Yuzhou Zhuang, Satoshi Kondo, Maria Baldeon Calisto, Shaikh Muhammad Uzair Noman, Cancan Chen, Ipek Oguz, Rongguo Zhang, Mina Rezaei, Susana K. Lai-Yuen, Satoshi Kasai, Chih-Cheng Hung, Mohammad Yaqub, Lisheng Wang, Benoit M. Dawant, Cuntai Guan, Ritse Mann, Vincent Jaouen, Ji-Wung Han, Li Zhang, Jonathan Shapey, Tom Vercauteren
Date: 2025-06-13 00:00:00
Tasks: Benchmarking, Domain Adaptation, Segmentation

The cross-Modality Domain Adaptation (crossMoDA) challenge series, initiated in 2021 in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), focuses on unsupervised cross-modality segmentation, learning from contrast-enhanced T1 (ceT1) and transferring to T2 MRI. The task is an extreme example of domain shift chosen to serve as a meaningful and illustrative benchmark. From a clinical application perspective, it aims to automate Vestibular Schwannoma (VS) and cochlea segmentation on T2 scans for more cost-effective VS management. Over time, the challenge objectives have evolved to enhance its clinical relevance. The challenge evolved from using single-institutional data and basic segmentation in 2021 to incorporating multi-institutional data and Koos grading in 2022, and by 2023, it included heterogeneous routine data and sub-segmentation of intra- and extra-meatal tumour components. In this work, we report the findings of the 2022 and 2023 editions and perform a retrospective analysis of the challenge progression over the years. The observations from the successive challenge contributions indicate that the number of outliers decreases with an expanding dataset. This is notable since the diversity of scanning protocols of the datasets concurrently increased. The winning approach of the 2023 edition reduced the number of outliers on the 2021 and 2022 testing data, demonstrating how increased data heterogeneity can enhance segmentation performance even on homogeneous data. However, the cochlea Dice score declined in 2023, likely due to the added complexity from tumour sub-annotations affecting overall segmentation performance. While progress is still needed for clinically acceptable VS segmentation, the plateauing performance suggests that a more challenging cross-modal task may better serve future benchmarking.
Vision Transformer-Based Time-Series Image Reconstruction for Cloud-Filling Applications
Authors: Lujun Li, Yiqun Wang, Radu State
Date: 2025-06-24 00:00:00
Tasks: Image Reconstruction, Time Series

Cloud cover in multispectral imagery (MSI) poses significant challenges for early season crop mapping, as it leads to missing or corrupted spectral information. Synthetic aperture radar (SAR) data, which is not affected by cloud interference, offers a complementary solution, but lack sufficient spectral detail for precise crop mapping. To address this, we propose a novel framework, Time-series MSI Image Reconstruction using Vision Transformer (ViT), to reconstruct MSI data in cloud-covered regions by leveraging the temporal coherence of MSI and the complementary information from SAR from the attention mechanism. Comprehensive experiments, using rigorous reconstruction evaluation metrics, demonstrate that Time-series ViT framework significantly outperforms baselines that use non-time-series MSI and SAR or time-series MSI without SAR, effectively enhancing MSI image reconstruction in cloud-covered regions.
Learning from Anatomy: Supervised Anatomical Pretraining (SAP) for Improved Metastatic Bone Disease Segmentation in Whole-Body MRI
Authors: Joris Wuts, Jakub Ceranka, Nicolas Michoux, Frédéric Lecouvet, Jef Vandemeulebroucke
Date: 2025-06-24 00:00:00
Tasks: Anatomy, Inductive Bias, Lesion Detection, Self-Supervised Learning

The segmentation of metastatic bone disease (MBD) in whole-body MRI (WB-MRI) is a challenging problem. Due to varying appearances and anatomical locations of lesions, ambiguous boundaries, and severe class imbalance, obtaining reliable segmentations requires large, well-annotated datasets capturing lesion variability. Generating such datasets requires substantial time and expertise, and is prone to error. While self-supervised learning (SSL) can leverage large unlabeled datasets, learned generic representations often fail to capture the nuanced features needed for accurate lesion detection. In this work, we propose a Supervised Anatomical Pretraining (SAP) method that learns from a limited dataset of anatomical labels. First, an MRI-based skeletal segmentation model is developed and trained on WB-MRI scans from healthy individuals for high-quality skeletal delineation. Then, we compare its downstream efficacy in segmenting MBD on a cohort of 44 patients with metastatic prostate cancer, against both a baseline random initialization and a state-of-the-art SSL method. SAP significantly outperforms both the baseline and SSL-pretrained models, achieving a normalized surface Dice of 0.76 and a Dice coefficient of 0.64. The method achieved a lesion detection F2 score of 0.44, improving on 0.24 (baseline) and 0.31 (SSL). When considering only clinically relevant lesions larger than 1~ml, SAP achieves a detection sensitivity of 100% in 28 out of 32 patients. Learning bone morphology from anatomy yields an effective and domain-relevant inductive bias that can be leveraged for the downstream segmentation task of bone lesions. All code and models are made publicly available.
Angio-Diff: Learning a Self-Supervised Adversarial Diffusion Model for Angiographic Geometry Generation
Authors: Zhifeng Wang, Renjiao Yi, Xin Wen, Chenyang Zhu, Kai Xu, Kunlun He
Date: 2025-06-24 00:00:00
Tasks: Image Generation

Vascular diseases pose a significant threat to human health, with X-ray angiography established as the gold standard for diagnosis, allowing for detailed observation of blood vessels. However, angiographic X-rays expose personnel and patients to higher radiation levels than non-angiographic X-rays, which are unwanted. Thus, modality translation from non-angiographic to angiographic X-rays is desirable. Data-driven deep approaches are hindered by the lack of paired large-scale X-ray angiography datasets. While making high-quality vascular angiography synthesis crucial, it remains challenging. We find that current medical image synthesis primarily operates at pixel level and struggles to adapt to the complex geometric structure of blood vessels, resulting in unsatisfactory quality of blood vessel image synthesis, such as disconnections or unnatural curvatures. To overcome this issue, we propose a self-supervised method via diffusion models to transform non-angiographic X-rays into angiographic X-rays, mitigating data shortages for data-driven approaches. Our model comprises a diffusion model that learns the distribution of vascular data from diffusion latent, a generator for vessel synthesis, and a mask-based adversarial module. To enhance geometric accuracy, we propose a parametric vascular model to fit the shape and distribution of blood vessels. The proposed method contributes a pipeline and a synthetic dataset for X-ray angiography. We conducted extensive comparative and ablation experiments to evaluate the Angio-Diff. The results demonstrate that our method achieves state-of-the-art performance in synthetic angiography image quality and more accurately synthesizes the geometric structure of blood vessels. The code is available at https://github.com/zfw-cv/AngioDiff.
NAADA: A Noise-Aware Attention Denoising Autoencoder for Dental Panoramic Radiographs
Authors: Khuram Naveed, Bruna Neves de Freitas, Ruben Pauwels
Date: 2025-06-24 00:00:00
Tasks: Denoising, Diagnostic, Image Restoration

Convolutional denoising autoencoders (DAEs) are powerful tools for image restoration. However, they inherit a key limitation of convolutional neural networks (CNNs): they tend to recover low-frequency features, such as smooth regions, more effectively than high-frequency details. This leads to the loss of fine details, which is particularly problematic in dental radiographs where preserving subtle anatomical structures is crucial. While self-attention mechanisms can help mitigate this issue by emphasizing important features, conventional attention methods often prioritize features corresponding to cleaner regions and may overlook those obscured by noise. To address this limitation, we propose a noise-aware self-attention method, which allows the model to effectively focus on and recover key features even within noisy regions. Building on this approach, we introduce the noise-aware attention-enhanced denoising autoencoder (NAADA) network for enhancing noisy panoramic dental radiographs. Compared with the recent state of the art (and much heavier) methods like Uformer, MResDNN etc., our method improves the reconstruction of fine details, ensuring better image quality and diagnostic accuracy.
Reconsidering Explicit Longitudinal Mammography Alignment for Enhanced Breast Cancer Risk Prediction
Authors: Solveig Thrun, Stine Hansen, Zijun Sun, Nele Blum, Suaiba A. Salahuddin, Kristoffer Wickstrøm, Elisabeth Wetzer, Robert Jenssen, Maik Stille, Michael Kampffmeyer
Date: 2025-06-24 00:00:00
Tasks: Breast Cancer Detection, Prediction

Regular mammography screening is essential for early breast cancer detection. Deep learning-based risk prediction methods have sparked interest to adjust screening intervals for high-risk groups. While early methods focused only on current mammograms, recent approaches leverage the temporal aspect of screenings to track breast tissue changes over time, requiring spatial alignment across different time points. Two main strategies for this have emerged: explicit feature alignment through deformable registration and implicit learned alignment using techniques like transformers, with the former providing more control. However, the optimal approach for explicit alignment in mammography remains underexplored. In this study, we provide insights into where explicit alignment should occur (input space vs. representation space) and if alignment and risk prediction should be jointly optimized. We demonstrate that jointly learning explicit alignment in representation space while optimizing risk estimation performance, as done in the current state-of-the-art approach, results in a trade-off between alignment quality and predictive performance and show that image-level alignment is superior to representation-level alignment, leading to better deformation field quality and enhanced risk prediction accuracy. The code is available at https://github.com/sot176/Longitudinal_Mammogram_Alignment.git.