pwc-archive/papers-with-abstracts huggingface dataset:
MoEDiff-SR: Mixture of Experts-Guided Diffusion Model for Region-Adaptive MRI Super-Resolution
Authors: Zhe Wang, Yuhua Ru, Aladine Chetouani, Fang Chen, Fabian Bauer, Liping Zhang, Didier Hans, Rachid Jennane, Mohamed Jarraya, Yung Hsin Chen
Date: 2025-04-09 00:00:00
Tasks: Computational Efficiency, Denoising, Diagnostic, Mixture-of-Experts, Super-Resolution

Magnetic Resonance Imaging (MRI) at lower field strengths (e.g., 3T) suffers from limited spatial resolution, making it challenging to capture fine anatomical details essential for clinical diagnosis and neuroimaging research. To overcome this limitation, we propose MoEDiff-SR, a Mixture of Experts (MoE)-guided diffusion model for region-adaptive MRI Super-Resolution (SR). Unlike conventional diffusion-based SR models that apply a uniform denoising process across the entire image, MoEDiff-SR dynamically selects specialized denoising experts at a fine-grained token level, ensuring region-specific adaptation and enhanced SR performance. Specifically, our approach first employs a Transformer-based feature extractor to compute multi-scale patch embeddings, capturing both global structural information and local texture details. The extracted feature embeddings are then fed into an MoE gating network, which assigns adaptive weights to multiple diffusion-based denoisers, each specializing in different brain MRI characteristics, such as centrum semiovale, sulcal and gyral cortex, and grey-white matter junction. The final output is produced by aggregating the denoised results from these specialized experts according to dynamically assigned gating probabilities. Experimental results demonstrate that MoEDiff-SR outperforms existing state-of-the-art methods in terms of quantitative image quality metrics, perceptual fidelity, and computational efficiency. Difference maps from each expert further highlight their distinct specializations, confirming the effective region-specific denoising capability and the interpretability of expert contributions. Additionally, clinical evaluation validates its superior diagnostic capability in identifying subtle pathological features, emphasizing its practical relevance in clinical neuroimaging. Our code is available at https://github.com/ZWang78/MoEDiff-SR.
Dual Deep Learning Approach for Non-invasive Renal Tumour Subtyping with VERDICT-MRI
Authors: Snigdha Sen, Lorna Smith, Lucy Caselton, Joey Clemente, Maxine Tran, Shonit Punwani, David Atkinson, Richard L Hesketh, Eleftheria Panagiotaki
Date: 2025-04-09 00:00:00
Tasks: Diffusion  MRI, feature selection, Self-Supervised Learning

This work aims to characterise renal tumour microstructure using diffusion MRI (dMRI); via the Vascular, Extracellular and Restricted Diffusion for Cytometry in Tumours (VERDICT)-MRI framework with self-supervised learning. Comprehensive datasets were acquired from 14 patients with 15 biopsy-confirmed renal tumours, with nine b-values in the range b=[0,2500]s/mm2. A three-compartment VERDICT model for renal tumours was fitted to the dMRI data using a self-supervised deep neural network, and ROIs were drawn by an experienced uroradiologist. An economical acquisition protocol for future studies with larger patient cohorts was optimised using a recursive feature selection approach. The VERDICT model described the diffusion data in renal tumours more accurately than IVIM or ADC. Combined with self-supervised deep learning, VERDICT identified significant differences in the intracellular volume fraction between cancerous and normal tissue, and in the vascular volume fraction between vascular and non-vascular. The feature selector yields a 4 b-value acquisition of b = [70,150,1000,2000], with a duration of 14 minutes.
Longitudinal Assessment of Lung Lesion Burden in CT
Authors: Tejas Sudharshan Mathai, Benjamin Hou, Ronald M. Summers
Date: 2025-04-09 00:00:00
Tasks: Anatomy, Lung Nodule Segmentation

In the U.S., lung cancer is the second major cause of death. Early detection of suspicious lung nodules is crucial for patient treatment planning, management, and improving outcomes. Many approaches for lung nodule segmentation and volumetric analysis have been proposed, but few have looked at longitudinal changes in total lung tumor burden. In this work, we trained two 3D models (nnUNet) with and without anatomical priors to automatically segment lung lesions and quantified total lesion burden for each patient. The 3D model without priors significantly outperformed ($p < .001$) the model trained with anatomy priors. For detecting clinically significant lesions $>$ 1cm, a precision of 71.3\%, sensitivity of 68.4\%, and F1-score of 69.8\% was achieved. For segmentation, a Dice score of 77.1 $\pm$ 20.3 and Hausdorff distance error of 11.7 $\pm$ 24.1 mm was obtained. The median lesion burden was 6.4 cc (IQR: 2.1, 18.1) and the median volume difference between manual and automated measurements was 0.02 cc (IQR: -2.8, 1.2). Agreements were also evaluated with linear regression and Bland-Altman plots. The proposed approach can produce a personalized evaluation of the total tumor burden for a patient and facilitate interval change tracking over time.
Leveraging Anatomical Priors for Automated Pancreas Segmentation on Abdominal CT
Authors: Anisa V. Prasad, Tejas Sudharshan Mathai, Pritam Mukherjee, Jianfei Liu, Ronald M. Summers
Date: 2025-04-09 00:00:00
Tasks: Anatomy, Automated Pancreas Segmentation, Pancreas Segmentation, Segmentation

An accurate segmentation of the pancreas on CT is crucial to identify pancreatic pathologies and extract imaging-based biomarkers. However, prior research on pancreas segmentation has primarily focused on modifying the segmentation model architecture or utilizing pre- and post-processing techniques. In this article, we investigate the utility of anatomical priors to enhance the segmentation performance of the pancreas. Two 3D full-resolution nnU-Net models were trained, one with 8 refined labels from the public PANORAMA dataset, and another that combined them with labels derived from the public TotalSegmentator (TS) tool. The addition of anatomical priors resulted in a 6\% increase in Dice score ($p < .001$) and a 36.5 mm decrease in Hausdorff distance for pancreas segmentation ($p < .001$). Moreover, the pancreas was always detected when anatomy priors were used, whereas there were 8 instances of failed detections without their use. The use of anatomy priors shows promise for pancreas segmentation and subsequent derivation of imaging biomarkers.
DIMA: DIffusing Motion Artifacts for unsupervised correction in brain MRI images
Authors: Paolo Angella, Luca Balbi, Fabrizio Ferrando, Paolo Traverso, Rosario Varriale, Vito Paolo Pastore, Matteo Santacesaria
Date: 2025-04-09 00:00:00
Tasks: Diagnostic

Motion artifacts remain a significant challenge in Magnetic Resonance Imaging (MRI), compromising diagnostic quality and potentially leading to misdiagnosis or repeated scans. Existing deep learning approaches for motion artifact correction typically require paired motion-free and motion-affected images for training, which are rarely available in clinical settings. To overcome this requirement, we present DIMA (DIffusing Motion Artifacts), a novel framework that leverages diffusion models to enable unsupervised motion artifact correction in brain MRI. Our two-phase approach first trains a diffusion model on unpaired motion-affected images to learn the distribution of motion artifacts. This model then generates realistic motion artifacts on clean images, creating paired datasets suitable for supervised training of correction networks. Unlike existing methods, DIMA operates without requiring k-space manipulation or detailed knowledge of MRI sequence parameters, making it adaptable across different scanning protocols and hardware. Comprehensive evaluations across multiple datasets and anatomical planes demonstrate that our method achieves comparable performance to state-of-the-art supervised approaches while offering superior generalizability to real clinical data. DIMA represents a significant advancement in making motion artifact correction more accessible for routine clinical use, potentially reducing the need for repeat scans and improving diagnostic accuracy.
Q-Agent: Quality-Driven Chain-of-Thought Image Restoration Agent through Robust Multimodal Large Language Model
Authors: Yingjie Zhou, JieZhang Cao, ZiCheng Zhang, Farong Wen, Yanwei Jiang, Jun Jia, Xiaohong Liu, Xiongkuo Min, Guangtao Zhai
Date: 2025-04-09 00:00:00
Tasks: Image Quality Assessment, Image Restoration, Language Modeling, Language Modelling, Large Language Model, Multimodal Large Language Model

Image restoration (IR) often faces various complex and unknown degradations in real-world scenarios, such as noise, blurring, compression artifacts, and low resolution, etc. Training specific models for specific degradation may lead to poor generalization. To handle multiple degradations simultaneously, All-in-One models might sacrifice performance on certain types of degradation and still struggle with unseen degradations during training. Existing IR agents rely on multimodal large language models (MLLM) and a time-consuming rolling-back selection strategy neglecting image quality. As a result, they may misinterpret degradations and have high time and computational costs to conduct unnecessary IR tasks with redundant order. To address these, we propose a Quality-Driven agent (Q-Agent) via Chain-of-Thought (CoT) restoration. Specifically, our Q-Agent consists of robust degradation perception and quality-driven greedy restoration. The former module first fine-tunes MLLM, and uses CoT to decompose multi-degradation perception into single-degradation perception tasks to enhance the perception of MLLMs. The latter employs objective image quality assessment (IQA) metrics to determine the optimal restoration sequence and execute the corresponding restoration algorithms. Experimental results demonstrate that our Q-Agent achieves superior IR performance compared to existing All-in-One models.
VideoSPatS: Video SPatiotemporal Splines for Disentangled Occlusion, Appearance and Motion Modeling and Editing
Authors: Juan Luis Gonzalez Bello, Xu Yao, Alex Whelan, Kyle Olszewski, Hyeongwoo Kim, Pablo Garrido
Date: 2025-04-08 00:00:00
Proceeding: CVPR 2025 1
Tasks: Disentanglement, Motion Disentanglement, Video Editing

We present an implicit video representation for occlusions, appearance, and motion disentanglement from monocular videos, which we call Video SPatiotemporal Splines (VideoSPatS). Unlike previous methods that map time and coordinates to deformation and canonical colors, our VideoSPatS maps input coordinates into Spatial and Color Spline deformation fields $D_s$ and $D_c$, which disentangle motion and appearance in videos. With spline-based parametrization, our method naturally generates temporally consistent flow and guarantees long-term temporal consistency, which is crucial for convincing video editing. Using multiple prediction branches, our VideoSPatS model also performs layer separation between the latent video and the selected occluder. By disentangling occlusions, appearance, and motion, our method enables better spatiotemporal modeling and editing of diverse videos, including in-the-wild talking head videos with challenging occlusions, shadows, and specularities while maintaining an appropriate canonical space for editing. We also present general video modeling results on the DAVIS and CoDeF datasets, as well as our own talking head video dataset collected from open-source web videos. Extensive ablations show the combination of $D_s$ and $D_c$ under neural splines can overcome motion and appearance ambiguities, paving the way for more advanced video editing models.
Examining Joint Demosaicing and Denoising for Single-, Quad-, and Nona-Bayer Patterns
Authors: SaiKiran Tedla, Abhijith Punnappurath, Luxi Zhao, Michael S. Brown
Date: 2025-04-08 00:00:00
Tasks: Demosaicking, Denoising, Joint Demosaicing and Denoising

Camera sensors have color filters arranged in a mosaic layout, traditionally following the Bayer pattern. Demosaicing is a critical step camera hardware applies to obtain a full-channel RGB image. Many smartphones now have multiple sensors with different patterns, such as Quad-Bayer or Nona-Bayer. Most modern deep network-based models perform joint demosaicing and denoising with the current strategy of training a separate network per pattern. Relying on individual models per pattern requires additional memory overhead and makes it challenging to switch quickly between cameras. In this work, we are interested in analyzing strategies for joint demosaicing and denoising for the three main mosaic layouts (1x1 Single-Bayer, 2x2 Quad-Bayer, and 3x3 Nona-Bayer). We found that concatenating a three-channel mosaic embedding to the input image and training with a unified demosaicing architecture yields results that outperform existing Quad-Bayer and Nona-Bayer models and are comparable to Single-Bayer models. Additionally, we describe a maskout strategy that enhances the model performance and facilitates dead pixel correction -- a step often overlooked by existing AI-based demosaicing models. As part of this effort, we captured a new demosaicing dataset of 638 RAW images that contain challenging scenes with patches annotated for training, validation, and testing.
GIGA: Generalizable Sparse Image-driven Gaussian Avatars
Authors: Anton Zubekhin, Heming Zhu, Paulo Gotardo, Thabo Beeler, Marc Habermann, Christian Theobalt
Date: 2025-04-08 00:00:00

Driving a high-quality and photorealistic full-body human avatar, from only a few RGB cameras, is a challenging problem that has become increasingly relevant with emerging virtual reality technologies. To democratize such technology, a promising solution may be a generalizable method that takes sparse multi-view images of an unseen person and then generates photoreal free-view renderings of such identity. However, the current state of the art is not scalable to very large datasets and, thus, lacks in diversity and photorealism. To address this problem, we propose a novel, generalizable full-body model for rendering photoreal humans in free viewpoint, as driven by sparse multi-view video. For the first time in literature, our model can scale up training to thousands of subjects while maintaining high photorealism. At the core, we introduce a MultiHeadUNet architecture, which takes sparse multi-view images in texture space as input and predicts Gaussian primitives represented as 2D texels on top of a human body mesh. Importantly, we represent sparse-view image information, body shape, and the Gaussian parameters in 2D so that we can design a deep and scalable architecture entirely based on 2D convolutions and attention mechanisms. At test time, our method synthesizes an articulated 3D Gaussian-based avatar from as few as four input views and a tracked body template for unseen identities. Our method excels over prior works by a significant margin in terms of cross-subject generalization capability as well as photorealism.
Retuve: Automated Multi-Modality Analysis of Hip Dysplasia with Open Source AI
Authors: Adam McArthur, Stephanie Wichuk, Stephen Burnside, Andrew Kirby, Alexander Scammon, Damian Sol, Abhilash Hareendranathan, Jacob L. Jaremko
Date: 2025-04-08 00:00:00
Tasks: Diagnostic

Developmental dysplasia of the hip (DDH) poses significant diagnostic challenges, hindering timely intervention. Current screening methodologies lack standardization, and AI-driven studies suffer from reproducibility issues due to limited data and code availability. To address these limitations, we introduce Retuve, an open-source framework for multi-modality DDH analysis, encompassing both ultrasound (US) and X-ray imaging. Retuve provides a complete and reproducible workflow, offering open datasets comprising expert-annotated US and X-ray images, pre-trained models with training code and weights, and a user-friendly Python Application Programming Interface (API). The framework integrates segmentation and landmark detection models, enabling automated measurement of key diagnostic parameters such as the alpha angle and acetabular index. By adhering to open-source principles, Retuve promotes transparency, collaboration, and accessibility in DDH research. This initiative has the potential to democratize DDH screening, facilitate early diagnosis, and ultimately improve patient outcomes by enabling widespread screening and early intervention. The GitHub repository/code can be found here: https://github.com/radoss-org/retuve
OSDM-MReg: Multimodal Image Registration based One Step Diffusion Model
Authors: Xiaochen Wei, Weiwei Guo, Wenxian Yu, Feiming Wei, Dongying Li
Date: 2025-04-08 00:00:00
Tasks: Denoising, Image Registration, Image-to-Image Translation

Multimodal remote sensing image registration aligns images from different sensors for data fusion and analysis. However, current methods often fail to extract modality-invariant features when aligning image pairs with large nonlinear radiometric differences. To address this issues, we propose OSDM-MReg, a novel multimodal image registration framework based image-to-image translation to eliminate the gap of multimodal images. Firstly, we propose a novel one-step unaligned target-guided conditional denoising diffusion probabilistic models(UTGOS-CDDPM)to translate multimodal images into a unified domain. In the inference stage, traditional conditional DDPM generate translated source image by a large number of iterations, which severely slows down the image registration task. To address this issues, we use the unaligned traget image as a condition to promote the generation of low-frequency features of the translated source image. Furthermore, during the training stage, we add the inverse process of directly predicting the translated image to ensure that the translated source image can be generated in one step during the testing stage. Additionally, to supervised the detail features of translated source image, we propose a new perceptual loss that focuses on the high-frequency feature differences between the translated and ground-truth images. Finally, a multimodal multiscale image registration network (MM-Reg) fuse the multimodal feature of the unimodal images and multimodal images by proposed multimodal feature fusion strategy. Experiments demonstrate superior accuracy and efficiency across various multimodal registration tasks, particularly for SAR-optical image pairs.
AVP-AP: Self-supervised Automatic View Positioning in 3D cardiac CT via Atlas Prompting
Authors: Xiaolin Fan, Yan Wang, Yingying Zhang, Mingkun Bao, Bosen Jia, Dong Lu, Yifan Gu, Jian Cheng, Haogang Zhu
Date: 2025-04-08 00:00:00
Tasks: Computed Tomography (CT), SSIM

Automatic view positioning is crucial for cardiac computed tomography (CT) examinations, including disease diagnosis and surgical planning. However, it is highly challenging due to individual variability and large 3D search space. Existing work needs labor-intensive and time-consuming manual annotations to train view-specific models, which are limited to predicting only a fixed set of planes. However, in real clinical scenarios, the challenge of positioning semantic 2D slices with any orientation into varying coordinate space in arbitrary 3D volume remains unsolved. We thus introduce a novel framework, AVP-AP, the first to use Atlas Prompting for self-supervised Automatic View Positioning in the 3D CT volume. Specifically, this paper first proposes an atlas prompting method, which generates a 3D canonical atlas and trains a network to map slices into their corresponding positions in the atlas space via a self-supervised manner. Then, guided by atlas prompts corresponding to the given query images in a reference CT, we identify the coarse positions of slices in the target CT volume using rigid transformation between the 3D atlas and target CT volume, effectively reducing the search space. Finally, we refine the coarse positions by maximizing the similarity between the predicted slices and the query images in the feature space of a given foundation model. Our framework is flexible and efficient compared to other methods, outperforming other methods by 19.8% average structural similarity (SSIM) in arbitrary view positioning and achieving 9% SSIM in two-chamber view compared to four radiologists. Meanwhile, experiments on a public dataset validate our framework's generalizability.
Diabetic Retinopathy Detection Based on Convolutional Neural Networks with SMOTE and CLAHE Techniques Applied to Fundus Images
Authors: Sidhiq Mardianta, Affandy, Catur Supriyanto, Adi Wijaya
Date: 2025-04-08 00:00:00
Tasks: Binary Classification, Diabetic Retinopathy Detection

Diabetic retinopathy (DR) is one of the major complications in diabetic patients' eyes, potentially leading to permanent blindness if not detected timely. This study aims to evaluate the accuracy of artificial intelligence (AI) in diagnosing DR. The method employed is the Synthetic Minority Over-sampling Technique (SMOTE) algorithm, applied to identify DR and its severity stages from fundus images using the public dataset "APTOS 2019 Blindness Detection." Literature was reviewed via ScienceDirect, ResearchGate, Google Scholar, and IEEE Xplore. Classification results using Convolutional Neural Network (CNN) showed the best performance for the binary classes normal (0) and DR (1) with an accuracy of 99.55%, precision of 99.54%, recall of 99.54%, and F1-score of 99.54%. For the multiclass classification No_DR (0), Mild (1), Moderate (2), Severe (3), Proliferate_DR (4), the accuracy was 95.26%, precision 95.26%, recall 95.17%, and F1-score 95.23%. Evaluation using the confusion matrix yielded results of 99.68% for binary classification and 96.65% for multiclass. This study highlights the significant potential in enhancing the accuracy of DR diagnosis compared to traditional human analysis
POMATO: Marrying Pointmap Matching with Temporal Motion for Dynamic 3D Reconstruction
Authors: Songyan Zhang, Yongtao Ge, Jinyuan Tian, Guangkai Xu, Hao Chen, Chen Lv, Chunhua Shen
Date: 2025-04-08 00:00:00
Tasks: 3D Reconstruction, Depth Estimation, Point Tracking, Pose Estimation

3D reconstruction in dynamic scenes primarily relies on the combination of geometry estimation and matching modules where the latter task is pivotal for distinguishing dynamic regions which can help to mitigate the interference introduced by camera and object motion. Furthermore, the matching module explicitly models object motion, enabling the tracking of specific targets and advancing motion understanding in complex scenarios. Recently, the proposed representation of pointmap in DUSt3R suggests a potential solution to unify both geometry estimation and matching in 3D space, but it still struggles with ambiguous matching in dynamic regions, which may hamper further improvement. In this work, we present POMATO, a unified framework for dynamic 3D reconstruction by marrying pointmap matching with temporal motion. Specifically, our method first learns an explicit matching relationship by mapping RGB pixels from both dynamic and static regions across different views to 3D pointmaps within a unified coordinate system. Furthermore, we introduce a temporal motion module for dynamic motions that ensures scale consistency across different frames and enhances performance in tasks requiring both precise geometry and reliable matching, most notably 3D point tracking. We show the effectiveness of the proposed pointmap matching and temporal fusion paradigm by demonstrating the remarkable performance across multiple downstream tasks, including video depth estimation, 3D point tracking, and pose estimation. Code and models are publicly available at https://github.com/wyddmw/POMATO.