pwc-archive/papers-with-abstracts huggingface dataset:
PM-Gati Shakti: Advancing India's Energy Future through Demand Forecasting -- A Case Study
Authors: SujayKumar Reddy M, Gopakumar G
Date: 2023-07-30 00:00:00
Tasks: Demand Forecasting, Scheduling

PM-Gati-Shakti Initiative, integration of ministries, including railways, ports, waterways, logistic infrastructure, mass transport, airports, and roads. Aimed at enhancing connectivity and bolstering the competitiveness of Indian businesses, the initiative focuses on six pivotal pillars known as "Connectivity for Productivity": comprehensiveness, prioritization, optimization, synchronization, analytical, and dynamic. In this study, we explore the application of these pillars to address the problem of "Maximum Demand Forecasting in Delhi." Electricity forecasting plays a very significant role in the power grid as it is required to maintain a balance between supply and load demand at all times, to provide a quality electricity supply, for Financial planning, generation reserve, and many more. Forecasting helps not only in Production Planning but also in Scheduling like Import / Export which is very often in India and mostly required by the rural areas and North Eastern Regions of India. As Electrical Forecasting includes many factors which cannot be detected by the models out there, We use Classical Forecasting Techniques to extract the seasonal patterns from the daily data of Maximum Demand for the Union Territory Delhi. This research contributes to the power supply industry by helping to reduce the occurrence of disasters such as blackouts, power cuts, and increased tariffs imposed by regulatory commissions. The forecasting techniques can also help in reducing OD and UD of Power for different regions. We use the Data provided by a department from the Ministry of Power and use different forecast models including Seasonal forecasts for daily data.
GIST-AiTeR Speaker Diarization System for VoxCeleb Speaker Recognition Challenge (VoxSRC) 2023
Authors: Dongkeon Park, Ji Won Kim, Kang Ryeol Kim, Do Hyun Lee, Hong Kook Kim
Date: 2023-08-15 00:00:00
Tasks: speaker-diarization, Speaker Diarization, Speaker Recognition

This report describes the submission system by the GIST-AiTeR team for the VoxCeleb Speaker Recognition Challenge 2023 (VoxSRC-23) Track 4. Our submission system focuses on implementing diverse speaker diarization (SD) techniques, including ResNet293 and MFA-Conformer with different combinations of segment and hop length. Then, those models are combined into an ensemble model. The ResNet293 and MFA-Conformer models exhibited the diarization error rates (DERs) of 3.65% and 3.83% on VAL46, respectively. The submitted ensemble model provided a DER of 3.50% on VAL46, and consequently, it achieved a DER of 4.88% on the VoxSRC-23 test set.
The DKU-MSXF Diarization System for the VoxCeleb Speaker Recognition Challenge 2023
Authors: Ming Cheng, Weiqing Wang, Xiaoyi Qin, Yuke Lin, Ning Jiang, Guoqing Zhao, Ming Li
Date: 2023-08-15 00:00:00
Tasks: Action Detection, Activity Detection, Clustering, Speaker Recognition

This paper describes the DKU-MSXF submission to track 4 of the VoxCeleb Speaker Recognition Challenge 2023 (VoxSRC-23). Our system pipeline contains voice activity detection, clustering-based diarization, overlapped speech detection, and target-speaker voice activity detection, where each procedure has a fused output from 3 sub-models. Finally, we fuse different clustering-based and TSVAD-based diarization systems using DOVER-Lap and achieve the 4.30% diarization error rate (DER), which ranks first place on track 4 of the challenge leaderboard.
A deep deformable residual learning network for SAR images segmentation
Authors: Chenwei Wang, Jifang Pei, Yulin Huang, Jianyu Yang
Date: 2023-08-15 00:00:00
Tasks: Learning Theory, Segmentation

Reliable automatic target segmentation in Synthetic Aperture Radar (SAR) imagery has played an important role in the SAR fields. Different from the traditional methods, Spectral Residual (SR) and CFAR detector, with the recent adavance in machine learning theory, there has emerged a novel method for SAR target segmentation, based on the deep learning networks. In this paper, we proposed a deep deformable residual learning network for target segmentation that attempts to preserve the precise contour of the target. For this, the deformable convolutional layers and residual learning block are applied, which could extract and preserve the geometric information of the targets as much as possible. Based on the Moving and Stationary Target Acquisition and Recognition (MSTAR) data set, experimental results have shown the superiority of the proposed network for the precise targets segmentation.
Brain Tumor Detection Based on a Novel and High-Quality Prediction of the Tumor Pixel Distributions
Authors: Yanming Sun, Chunyan Wang
Date: 2023-08-14 00:00:00

In this paper, we propose a system to detect brain tumor in 3D MRI brain scans of Flair modality. It performs 2 functions: (a) predicting gray-level and locational distributions of the pixels in the tumor regions and (b) generating tumor mask in pixel-wise precision. To facilitate 3D data analysis and processing, we introduced a 2D histogram presentation that comprehends the gray-level distribution and pixel-location distribution of a 3D object. In the proposed system, particular 2D histograms, in which tumor-related feature data get concentrated, are established by exploiting the left-right asymmetry of a brain structure. A modulation function is generated from the input data of each patient case and applied to the 2D histograms to attenuate the element irrelevant to the tumor regions. The prediction of the tumor pixel distribution is done in 3 steps, on the axial, coronal and sagittal slice series, respectively. In each step, the prediction result helps to identify/remove tumor-free slices, increasing the tumor information density in the remaining data to be applied to the next step. After the 3-step removal, the 3D input is reduced to a minimum bounding box of the tumor region. It is used to finalize the prediction and then transformed into a 3D tumor mask, by means of gray level thresholding and low-pass-based morphological operations. The final prediction result is used to determine the critical threshold. The proposed system has been tested extensively with the data of more than one thousand patient cases in the datasets of BraTS 2018~21. The test results demonstrate that the predicted 2D histograms have a high degree of similarity with the true ones. The system delivers also very good tumor detection results, comparable to those of state-of-the-art CNN systems with mono-modality inputs, which is achieved at an extremely low computation cost and no need for training.
A Hierarchical Descriptor Framework for On-the-Fly Anatomical Location Matching between Longitudinal Studies
Authors: Halid Ziya Yerebakan, Yoshihisa Shinagawa, Mahesh Ranganath, Simon Allen-Raffl, Gerardo Hermosillo Valadez
Date: 2023-08-11 00:00:00
Tasks: CPU

We propose a method to match anatomical locations between pairs of medical images in longitudinal comparisons. The matching is made possible by computing a descriptor of the query point in a source image based on a hierarchical sparse sampling of image intensities that encode the location information. Then, a hierarchical search operation finds the corresponding point with the most similar descriptor in the target image. This simple yet powerful strategy reduces the computational time of mapping points to a millisecond scale on a single CPU. Thus, radiologists can compare similar anatomical locations in near real-time without requiring extra architectural costs for precomputing or storing deformation fields from registrations. Our algorithm does not require prior training, resampling, segmentation, or affine transformation steps. We have tested our algorithm on the recently published Deep Lesion Tracking dataset annotations. We observed more accurate matching compared to Deep Lesion Tracker while being 24 times faster than the most precise algorithm reported therein. We also investigated the matching accuracy on CT and MR modalities and compared the proposed algorithm's accuracy against ground truth consolidated from multiple radiologists.
Redesigning Out-of-Distribution Detection on 3D Medical Images
Authors: Anton Vasiliuk, Daria Frolova, Mikhail Belyaev, Boris Shirokikh
Date: 2023-08-07 00:00:00
Tasks: Image Segmentation, Medical Image Segmentation, Out-of-Distribution Detection, Segmentation, Semantic Segmentation

Detecting out-of-distribution (OOD) samples for trusted medical image segmentation remains a significant challenge. The critical issue here is the lack of a strict definition of abnormal data, which often results in artificial problem settings without measurable clinical impact. In this paper, we redesign the OOD detection problem according to the specifics of volumetric medical imaging and related downstream tasks (e.g., segmentation). We propose using the downstream model's performance as a pseudometric between images to define abnormal samples. This approach enables us to weigh different samples based on their performance impact without an explicit ID/OOD distinction. We incorporate this weighting in a new metric called Expected Performance Drop (EPD). EPD is our core contribution to the new problem design, allowing us to rank methods based on their clinical impact. We demonstrate the effectiveness of EPD-based evaluation in 11 CT and MRI OOD detection challenges.
On-site Energy Utilization Evaluation of Telecommunication Base Station: A Case Study of Western Uganda
Authors: Aceronga Kwocan, Mohammed Dahiru Buhari, Kelechi Ukagwu, Jonathan Serugunda
Date: 2023-08-15 00:00:00
Tasks: valid

Due to the widespread installation of Base Stations, the power consumption of cellular communication is increasing rapidly (BSs). Power consumption rises as traffic does, however, this scenario varies from geolocation to geolocation because sites in rural and urban areas have variable traffic loads. Therefore, in order to address various power consumption issues, it is necessary to analyze these sites and offer valid data that network operators can employ. This study took into account the impact of traffic load on energy consumption both in rural and urban locations in western Uganda because prior models did not adequately account for the impact of traffic load on both rural and urban sites. Regression models are used to examine these effects of traffic load on power consumption. Based on measurements taken for twenty-eight days in a row in six urban and rural areas, linear models have been presented. The findings showed that both rural and urban BTS were well-fitted by the suggested linear models. Depending on the layouts of the sites, it was found that energy consumption varied along with traffic, with the number of transceivers present having an impact on both the traffic load and energy consumption.
Statistical LOS/NLOS Classification for UWB Channels
Authors: Mohammed Dahiru Buhari, Tri Bagus Susilo, Irfan Khan, Bashir Olaniyi Sadiq
Date: 2023-08-15 00:00:00
Tasks: Classification, Outdoor Positioning

Ultrawideband (UWB) technology has attracted a lot of attention for indoor and outdoor positioning systems due to its high accuracy and robustness in non-line-of-sight (NLOS) environments. However, UWB signals are affected by multipath propagation which causes errors in localization. To overcome this problem, researchers have proposed various techniques for NLOS identification and mitigation. One of the approaches is statistical LOS/NLOS classification, which uses statistical parameters of the received signal to distinguish between LOS and NLOS channels. In this paper, we formulated several techniques which can be used for effectively classifying a Line of Sight (LOS) channel from a Non-Line of Sight (NLOS) channel. Various parameters obtained from Channel Impulse Response (CIR) like Skewness, Kurtosis, Root Mean Squared Delay Spread (RDS), Mean Excess Delay (MED), Energy, Energy Ratio, and Mean of Covariance Matrix are used for channel classification. In addition to this, the Joint Probability Density Functions (PDFs) of various parameters are used to improve the accuracy of UWB LOS/NLOS channel classification. Two different criteria-Likelihood Ratio and Hypothesis Tests are used for the identification of the channel.
Modeling and interpretation of single-cell proteogenomic data
Authors: Andrew Leduc, Hannah Harens, Nikolai Slavov
Date: 2023-08-14 00:00:00

Biological functions stem from coordinated interactions among proteins, nucleic acids and small molecules. Mass spectrometry technologies for reliable, high throughput single-cell proteomics will add a new modality to genomics and enable data-driven modeling of the molecular mechanisms coordinating proteins and nucleic acids at single-cell resolution. This promising potential requires estimating the reliability of measurements and computational analysis so that models can distinguish biological regulation from technical artifacts. We highlight different measurement modes that can support single-cell proteogenomic analysis and how to estimate their reliability. We then discuss approaches for developing both abstract and mechanistic models that aim to biologically interpret the measured differences across modalities, including specific applications to directed stem cell differentiation and to inferring protein interactions in cancer cells from the buffing of DNA copy-number variations. Single-cell proteogenomic data will support mechanistic models of direct molecular interactions that will provide generalizable and predictive representations of biological systems.
DiffHopp: A Graph Diffusion Model for Novel Drug Design via Scaffold Hopping
Authors: Jos Torge, Charles Harris, Simon V. Mathis, Pietro Lio
Date: 2023-08-14 00:00:00
Tasks: Drug Design, Drug Discovery

Scaffold hopping is a drug discovery strategy to generate new chemical entities by modifying the core structure, the \emph{scaffold}, of a known active compound. This approach preserves the essential molecular features of the original scaffold while introducing novel chemical elements or structural features to enhance potency, selectivity, or bioavailability. However, there is currently a lack of generative models specifically tailored for this task, especially in the pocket-conditioned context. In this work, we present DiffHopp, a conditional E(3)-equivariant graph diffusion model tailored for scaffold hopping given a known protein-ligand complex.
Benchmarking Generated Poses: How Rational is Structure-based Drug Design with Generative Models?
Authors: Charles Harris, Kieran Didi, Arian R. Jamasb, Chaitanya K. Joshi, Simon V. Mathis, Pietro Lio, Tom Blundell
Date: 2023-08-14 00:00:00
Tasks: Benchmarking, Drug Design

Deep generative models for structure-based drug design (SBDD), where molecule generation is conditioned on a 3D protein pocket, have received considerable interest in recent years. These methods offer the promise of higher-quality molecule generation by explicitly modelling the 3D interaction between a potential drug and a protein receptor. However, previous work has primarily focused on the quality of the generated molecules themselves, with limited evaluation of the 3D molecule \emph{poses} that these methods produce, with most work simply discarding the generated pose and only reporting a "corrected" pose after redocking with traditional methods. Little is known about whether generated molecules satisfy known physical constraints for binding and the extent to which redocking alters the generated interactions. We introduce PoseCheck, an extensive analysis of multiple state-of-the-art methods and find that generated molecules have significantly more physical violations and fewer key interactions compared to baselines, calling into question the implicit assumption that providing rich 3D structure information improves molecule complementarity. We make recommendations for future research tackling identified failure modes and hope our benchmark can serve as a springboard for future SBDD generative modelling work to have a real-world impact.
Reveal Your Images: Gradient Leakage Attack against Unbiased Sampling-Based Secure Aggregation
Authors: Y Yang, Z Ma, B Xiao, Y Liu, T Li, J Zhang
Date: 2023-04-28 00:00:00
Proceeding: IEEE Transactions on Knowledge and Data Engineering 2023 4
Tasks: Federated Learning

Recently, some Unbiased Gradient Sampling-based (UGS) methods are proposed to mitigate gradient leakage by introducing sampling and unbiased transformation, such as MinMax Sampling in SIGMOD '22. In this paper, we first propose a novel gradient leakage attack, GLAUS, to show that the UGS schemes still expose the privacy of private datapoints. Specifically, for the above secure aggregation scenario where the real gradient is not available, we demonstrate an idea to approximately infer the real gradient for gradient leakage attacks. Once the gradient can be approximately obtained, the security of UGS framework is downgraded to the original federated learning. The approximate gradient is refined by the following steps: 1) narrow the gradient searching range to the finite set; 2) obtain the magnitude of each gradient value approximately; 3) revise the gradient signs . Extensive experiments on six datasets show that our attack is effective in reconstructing the private datapoints with pixel-wise accuracy both on four network sizes and three image resolutions. Finally, we show a secure aggregation method to defend against the newly proposed attack while basically maintaining the gradient unbiased and communication-efficient of the UGS.
Genome assembly in the telomere-to-telomere era
Authors: Heng Li, Richard Durbin
Date: 2023-08-15 00:00:00

De novo assembly is the process of reconstructing the genome sequence of an organism from sequencing reads. Genome sequences are essential to biology, and assembly has been a central problem in bioinformatics for four decades. Until recently, genomes were typically assembled into fragments of a few megabases at best but technological advances in long-read sequencing now enable near complete chromosome-level assembly, also known as telomere-to-telomere assembly, for many organisms. Here we review recent progress on assembly algorithms and protocols. We focus on how to derive near telomere-to-telomere assemblies and discuss potential future developments.
Rapid model-guided design of organ-scale synthetic vasculature for biomanufacturing
Authors: Zachary A. Sexton, Andrew R. Hudson, Jessica E. Herrmann, Dan J. Shiwarski, Jonathan Pham, Jason M. Szafron, Sean M. Wu, Mark Skylar-Scott, Adam W. Feinberg, Alison Marsden
Date: 2023-08-15 00:00:00

Our ability to produce human-scale bio-manufactured organs is critically limited by the need for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily complex geometries, designing and printing vasculature capable of adequate perfusion has posed a major hurdle. Here, we introduce a model-driven design pipeline combining accelerated optimization methods for fast synthetic vascular tree generation and computational hemodynamics models. We demonstrate rapid generation, simulation, and 3D printing of synthetic vasculature in complex geometries, from small tissue constructs to organ scale networks. We introduce key algorithmic advances that all together accelerate synthetic vascular generation by more than 230-fold compared to standard methods and enable their use in arbitrarily complex shapes through localized implicit functions. Furthermore, we provide techniques for joining vascular trees into watertight networks suitable for hemodynamic CFD and 3D fabrication. We demonstrate that organ-scale vascular network models can be generated in silico within minutes and can be used to perfuse engineered and anatomic models including a bioreactor, annulus, bi-ventricular heart, and gyrus. We further show that this flexible pipeline can be applied to two common modes of bioprinting with free-form reversible embedding of suspended hydrogels and writing into soft matter. Our synthetic vascular tree generation pipeline enables rapid, scalable vascular model generation and fluid analysis for bio-manufactured tissues necessary for future scale up and production.
Efficacy of mannan-oligosaccharide and live yeast feed additives on performance, rumen morphology, serum biochemical parameters and muscle morphometric characteristics in buffalo calves
Authors: Muhammad Zeeshan, Saima Masood, Saima Ashraf, Shehla G. Bokhar, Hafsa Zainab, Saher Ijaz, Muhammad Usman, Ayesha Masood, Hafiz Faseeh U. Rehman, Mirza M. Usman
Date: 2023-08-14 00:00:00

The objective of the current study was to assess the effect of dietary supplementations of mannan-oligosaccharide, live yeast, and a combination of these two additives on growth performance, histo-morphology of the rumen, and muscle morphometric attributes in buffalo calves. A total of twenty buffalo calves (average weight of 25 kg) having 3 months of age were distributed according to a complete randomized design. All animals were individually stalled in the shed and were fed ad-libitum. Experimental animals were divided into four groups for 67 days: Control group(without the inclusion of dietary supplementation); MOS group (Mannan oligosaccharide 5 g/clave/day; Yeast group (Live yeast 2g/calve/day) and Mixed group (MOS + Live Yeast 2.5g + 1g )/calve/day. Experimental results revealed that combined supplementation of MOS and Yeast and MOS alone resulted in an increased number of short-chain fatty acids in the rumen as well as ruminal pH (P<0.05). Results showed a significant improvement in average daily gain and FCR of MOS and Mixed supplemented groups (P<0.05). Histomorphological evaluation of rumen mucosal epithelium showed a significant improvement in the mixed-supplemented group (P<0.05) as compared to the yeast-supplemented and control groups. Muscle quality parameters such as meat texture showed significant improvement in MOS and mix-supplemented groups. Histological examination of longissimus dorsi muscle cross-section showed a significantly higher(P<0.05) muscle fiber and muscle fascicle diameter in both MOS and mix-supplemented calves groups. In conclusion, the results of this experiment revealed that the dietary addition of MOS, Live yeast, and their combination have positive effects on growth performance, rumen histology indices, and muscle morphometric features in buffalo calves.
Reconstructing cryptocurrency processes via Markov chains
Authors: Tanya Araújo, Paulo Barbosa
Date: 2023-08-15 00:00:00

The growing attention on cryptocurrencies has led to increasing research on digital stock markets. Approaches and tools usually applied to characterize standard stocks have been applied to the digital ones. Among these tools is the identification of processes of market fluctuations. Being interesting stochastic processes, the usual statistical methods are appropriate tools for their reconstruction. There, besides chance, the description of a behavioural component shall be present whenever a deterministic pattern is ever found. Markov approaches are at the leading edge of this endeavour. In this paper, Markov chains of orders one to eight are considered as a way to forecast the dynamics of three major cryptocurrencies. It is accomplished using an empirical basis of intra-day returns. Besides forecasting, we investigate the existence of eventual long-memory components in each of those stochastic processes. Results show that predictions obtained from using the empirical probabilities are better than random choices.