pwc-archive/papers-with-abstracts huggingface dataset:
Applications of artificial intelligence in the analysis of histopathology images of gliomas: a review
Authors: Jan-Philipp Redlich, Friedrich Feuerhake, Joachim Weis, Nadine S. Schaadt, Sarah Teuber-Hanselmann, Christoph Buck, Sabine Luttmann, Andrea Eberle, Stefan Nikolin, Arno Appenzeller, Andreas Portmann, André Homeyer
Date: 2024-01-26 00:00:00
Tasks: Diagnostic, Survival Prediction

In recent years, the diagnosis of gliomas has become increasingly complex. Analysis of glioma histopathology images using artificial intelligence (AI) offers new opportunities to support diagnosis and outcome prediction. To give an overview of the current state of research, this review examines 83 publicly available research studies that have proposed AI-based methods for whole-slide histopathology images of human gliomas, covering the diagnostic tasks of subtyping (23/83), grading (27/83), molecular marker prediction (20/83), and survival prediction (29/83). All studies were reviewed with regard to methodological aspects as well as clinical applicability. It was found that the focus of current research is the assessment of hematoxylin and eosin-stained tissue sections of adult-type diffuse gliomas. The majority of studies (52/83) are based on the publicly available glioblastoma and low-grade glioma datasets from The Cancer Genome Atlas (TCGA) and only a few studies employed other datasets in isolation (16/83) or in addition to the TCGA datasets (15/83). Current approaches mostly rely on convolutional neural networks (63/83) for analyzing tissue at 20x magnification (35/83). A new field of research is the integration of clinical data, omics data, or magnetic resonance imaging (29/83). So far, AI-based methods have achieved promising results, but are not yet used in real clinical settings. Future work should focus on the independent validation of methods on larger, multi-site datasets with high-quality and up-to-date clinical and molecular pathology annotations to demonstrate routine applicability.
A General Framework for Robust G-Invariance in G-Equivariant Networks
Authors: Sophia Sanborn, Nina Miolane
Date: 2023-10-28 00:00:00
Proceeding: NeurIPS 2023 11

We introduce a general method for achieving robust group-invariance in group-equivariant convolutional neural networks ($G$-CNNs), which we call the $G$-triple-correlation ($G$-TC) layer. The approach leverages the theory of the triple-correlation on groups, which is the unique, lowest-degree polynomial invariant map that is also complete. Many commonly used invariant maps--such as the max--are incomplete: they remove both group and signal structure. A complete invariant, by contrast, removes only the variation due to the actions of the group, while preserving all information about the structure of the signal. The completeness of the triple correlation endows the $G$-TC layer with strong robustness, which can be observed in its resistance to invariance-based adversarial attacks. In addition, we observe that it yields measurable improvements in classification accuracy over standard Max $G$-Pooling in $G$-CNN architectures. We provide a general and efficient implementation of the method for any discretized group, which requires only a table defining the group's product structure. We demonstrate the benefits of this method for $G$-CNNs defined on both commutative and non-commutative groups--$SO(2)$, $O(2)$, $SO(3)$, and $O(3)$ (discretized as the cyclic $C8$, dihedral $D16$, chiral octahedral $O$ and full octahedral $O_h$ groups)--acting on $\mathbb{R}^2$ and $\mathbb{R}^3$ on both $G$-MNIST and $G$-ModelNet10 datasets.
Semantic Sensitivities and Inconsistent Predictions: Measuring the Fragility of NLI Models
Authors: Erik Arakelyan, Zhaoqi Liu, Isabelle Augenstein
Date: 2024-01-25 00:00:00
Tasks: Conditional Text Generation, Natural Language Inference, Natural Language Understanding, Sensitivity, Text Generation

Recent studies of the emergent capabilities of transformer-based Natural Language Understanding (NLU) models have indicated that they have an understanding of lexical and compositional semantics. We provide evidence that suggests these claims should be taken with a grain of salt: we find that state-of-the-art Natural Language Inference (NLI) models are sensitive towards minor semantics preserving surface-form variations, which lead to sizable inconsistent model decisions during inference. Notably, this behaviour differs from valid and in-depth comprehension of compositional semantics, however does neither emerge when evaluating model accuracy on standard benchmarks nor when probing for syntactic, monotonic, and logically robust reasoning. We propose a novel framework to measure the extent of semantic sensitivity. To this end, we evaluate NLI models on adversarially generated examples containing minor semantics-preserving surface-form input noise. This is achieved using conditional text generation, with the explicit condition that the NLI model predicts the relationship between the original and adversarial inputs as a symmetric equivalence entailment. We systematically study the effects of the phenomenon across NLI models for $\textbf{in-}$ and $\textbf{out-of-}$ domain settings. Our experiments show that semantic sensitivity causes performance degradations of $12.92\%$ and $23.71\%$ average over $\textbf{in-}$ and $\textbf{out-of-}$ domain settings, respectively. We further perform ablation studies, analysing this phenomenon across models, datasets, and variations in inference and show that semantic sensitivity can lead to major inconsistency within model predictions.
LongHealth: A Question Answering Benchmark with Long Clinical Documents
Authors: Lisa Adams, Felix Busch, Tianyu Han, Jean-Baptiste Excoffier, Matthieu Ortala, Alexander Löser, Hugo JWL. Aerts, Jakob Nikolas Kather, Daniel Truhn, Keno Bressem
Date: 2024-01-25 00:00:00
Tasks: Information Retrieval, Multiple-choice, Negation, Question Answering

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling real-world, lengthy clinical data. Methods: We present the LongHealth benchmark, comprising 20 detailed fictional patient cases across various diseases, with each case containing 5,090 to 6,754 words. The benchmark challenges LLMs with 400 multiple-choice questions in three categories: information extraction, negation, and sorting, challenging LLMs to extract and interpret information from large clinical documents. Results: We evaluated nine open-source LLMs with a minimum of 16,000 tokens and also included OpenAI's proprietary and cost-efficient GPT-3.5 Turbo for comparison. The highest accuracy was observed for Mixtral-8x7B-Instruct-v0.1, particularly in tasks focused on information retrieval from single and multiple patient documents. However, all models struggled significantly in tasks requiring the identification of missing information, highlighting a critical area for improvement in clinical data interpretation. Conclusion: While LLMs show considerable potential for processing long clinical documents, their current accuracy levels are insufficient for reliable clinical use, especially in scenarios requiring the identification of missing information. The LongHealth benchmark provides a more realistic assessment of LLMs in a healthcare setting and highlights the need for further model refinement for safe and effective clinical application. We make the benchmark and evaluation code publicly available.
K-QA: A Real-World Medical Q&A Benchmark
Authors: Itay Manes, Naama Ronn, David Cohen, Ran Ilan Ber, Zehavi Horowitz-Kugler, Gabriel Stanovsky
Date: 2024-01-25 00:00:00
Tasks: Hallucination, In-Context Learning, Retrieval

Ensuring the accuracy of responses provided by large language models (LLMs) is crucial, particularly in clinical settings where incorrect information may directly impact patient health. To address this challenge, we construct K-QA, a dataset containing 1,212 patient questions originating from real-world conversations held on K Health (an AI-driven clinical platform). We employ a panel of in-house physicians to answer and manually decompose a subset of K-QA into self-contained statements. Additionally, we formulate two NLI-based evaluation metrics approximating recall and precision: (1) comprehensiveness, measuring the percentage of essential clinical information in the generated answer and (2) hallucination rate, measuring the number of statements from the physician-curated response contradicted by the LLM answer. Finally, we use K-QA along with these metrics to evaluate several state-of-the-art models, as well as the effect of in-context learning and medically-oriented augmented retrieval schemes developed by the authors. Our findings indicate that in-context learning improves the comprehensiveness of the models, and augmented retrieval is effective in reducing hallucinations. We make K-QA available to to the community to spur research into medically accurate NLP applications.
Evaluating GPT-3.5's Awareness and Summarization Abilities for European Constitutional Texts with Shared Topics
Authors: Candida M. Greco, A. Tagarelli
Date: 2024-01-25 00:00:00
Tasks: Abstractive Text Summarization

Constitutions are foundational legal documents that underpin the governmental and societal structures. As such, they are a reflection of a nation's cultural and social uniqueness, but also contribute to establish topics of universal importance, like citizens' rights and duties (RD). In this work, using the renowned GPT-3.5, we leverage generative large language models to understand constitutional passages that transcend national boundaries. A key contribution of our study is the introduction of a novel application of abstractive summarization on a multi-source collection of constitutional texts, with a focus on European countries' constitution passages related to RD topics. Our results show the meaningfulness of GPT-3.5 to produce informative, coherent and faithful summaries capturing RD topics across European countries.
MEDs for PETs: Multilingual Euphemism Disambiguation for Potentially Euphemistic Terms
Authors: Patrick Lee, Alain Chirino Trujillo, Diana Cuevas Plancarte, Olumide Ebenezer Ojo, Xinyi Liu, Iyanuoluwa Shode, Yuan Zhao, Jing Peng, Anna Feldman
Date: 2024-01-25 00:00:00
Tasks: Cross-Lingual Transfer, Zero-Shot Learning

This study investigates the computational processing of euphemisms, a universal linguistic phenomenon, across multiple languages. We train a multilingual transformer model (XLM-RoBERTa) to disambiguate potentially euphemistic terms (PETs) in multilingual and cross-lingual settings. In line with current trends, we demonstrate that zero-shot learning across languages takes place. We also show cases where multilingual models perform better on the task compared to monolingual models by a statistically significant margin, indicating that multilingual data presents additional opportunities for models to learn about cross-lingual, computational properties of euphemisms. In a follow-up analysis, we focus on universal euphemistic "categories" such as death and bodily functions among others. We test to see whether cross-lingual data of the same domain is more important than within-language data of other domains to further understand the nature of the cross-lingual transfer.
Relative Value Biases in Large Language Models
Authors: William M. Hayes, Nicolas Yax, Stefano Palminteri
Date: 2024-01-25 00:00:00

Studies of reinforcement learning in humans and animals have demonstrated a preference for options that yielded relatively better outcomes in the past, even when those options are associated with lower absolute reward. The present study tested whether large language models would exhibit a similar bias. We had gpt-4-1106-preview (GPT-4 Turbo) and Llama-2-70B make repeated choices between pairs of options with the goal of maximizing payoffs. A complete record of previous outcomes was included in each prompt. Both models exhibited relative value decision biases similar to those observed in humans and animals. Making relative comparisons among outcomes more explicit magnified the bias, whereas prompting the models to estimate expected outcomes caused the bias to disappear. These results have implications for the potential mechanisms that contribute to context-dependent choice in human agents.
Looking Right is Sometimes Right: Investigating the Capabilities of Decoder-only LLMs for Sequence Labeling
Authors: David Dukić, Jan Šnajder
Date: 2024-01-25 00:00:00
Tasks: Causal Language Modeling, Decoder, Language Modeling, Language Modelling, Masked Language Modeling, Natural Language Understanding

Pre-trained language models based on masked language modeling (MLM) excel in natural language understanding (NLU) tasks. While fine-tuned MLM-based encoders consistently outperform causal language modeling decoders of comparable size, recent decoder-only large language models (LLMs) perform on par with smaller MLM-based encoders. Although their performance improves with scale, LLMs fall short of achieving state-of-the-art results in information extraction (IE) tasks, many of which are formulated as sequence labeling (SL). We hypothesize that LLMs' poor SL performance stems from causal masking, which prevents the model from attending to tokens on the right of the current token. Yet, how exactly and to what extent LLMs' performance on SL can be improved remains unclear. We explore techniques for improving the SL performance of open LLMs on IE tasks by applying layer-wise removal of the causal mask (CM) during LLM fine-tuning. This approach yields performance gains competitive with state-of-the-art SL models, matching or outperforming the results of CM removal from all blocks. Our findings hold for diverse SL tasks, demonstrating that open LLMs with layer-dependent CM removal outperform strong MLM-based encoders and even instruction-tuned LLMs.
Detecting Structured Language Alternations in Historical Documents by Combining Language Identification with Fourier Analysis
Authors: Hale Sirin, Sabrina Li, Tom Lippincott
Date: 2024-01-25 00:00:00
Tasks: Language Identification

In this study, we present a generalizable workflow to identify documents in a historic language with a nonstandard language and script combination, Armeno-Turkish. We introduce the task of detecting distinct patterns of multilinguality based on the frequency of structured language alternations within a document.
Enhancing Diagnostic Accuracy through Multi-Agent Conversations: Using Large Language Models to Mitigate Cognitive Bias
Authors: Yu He Ke, Rui Yang, Sui An Lie, Taylor Xin Yi Lim, Hairil Rizal Abdullah, Daniel Shu Wei Ting, Nan Liu
Date: 2024-01-26 00:00:00
Tasks: Decision Making, Diagnostic, Misconceptions

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study explores the role of large language models (LLMs) in mitigating these biases through the utilization of a multi-agent framework. We simulate the clinical decision-making processes through multi-agent conversation and evaluate its efficacy in improving diagnostic accuracy. Methods: A total of 16 published and unpublished case reports where cognitive biases have resulted in misdiagnoses were identified from the literature. In the multi-agent framework, we leveraged GPT-4 to facilitate interactions among four simulated agents to replicate clinical team dynamics. Each agent has a distinct role: 1) To make the final diagnosis after considering the discussions, 2) The devil's advocate and correct confirmation and anchoring bias, 3) The tutor and facilitator of the discussion to reduce premature closure bias, and 4) To record and summarize the findings. A total of 80 simulations were evaluated for the accuracy of initial diagnosis, top differential diagnosis and final two differential diagnoses. Results: In a total of 80 responses evaluating both initial and final diagnoses, the initial diagnosis had an accuracy of 0% (0/80), but following multi-agent discussions, the accuracy for the top differential diagnosis increased to 71.3% (57/80), and for the final two differential diagnoses, to 80.0% (64/80). Conclusions: The framework demonstrated an ability to re-evaluate and correct misconceptions, even in scenarios with misleading initial investigations. The LLM-driven multi-agent conversation framework shows promise in enhancing diagnostic accuracy in diagnostically challenging medical scenarios.
Alternative Speech: Complementary Method to Counter-Narrative for Better Discourse
Authors: SeungYoon Lee, Dahyun Jung, Chanjun Park, Seolhwa Lee, Heuiseok Lim
Date: 2024-01-26 00:00:00
Tasks: Specificity

We introduce the concept of "Alternative Speech" as a new way to directly combat hate speech and complement the limitations of counter-narrative. An alternative speech provides practical alternatives to hate speech in real-world scenarios by offering speech-level corrections to speakers while considering the surrounding context and promoting speakers to reform. Further, an alternative speech can combat hate speech alongside counter-narratives, offering a useful tool to address social issues such as racial discrimination and gender inequality. We propose the new concept and provide detailed guidelines for constructing the necessary dataset. Through discussion, we demonstrate that combining alternative speech and counter-narrative can be a more effective strategy for combating hate speech by complementing specificity and guiding capacity of counter-narrative. This paper presents another perspective for dealing with hate speech, offering viable remedies to complement the constraints of current approaches to mitigating harmful bias.
Query of CC: Unearthing Large Scale Domain-Specific Knowledge from Public Corpora
Authors: Zhaoye Fei, Yunfan Shao, Linyang Li, Zhiyuan Zeng, Conghui He, Hang Yan, Dahua Lin, Xipeng Qiu
Date: 2024-01-26 00:00:00
Tasks: Language Modeling, Language Modelling, Large Language Model

Large language models have demonstrated remarkable potential in various tasks, however, there remains a significant scarcity of open-source models and data for specific domains. Previous works have primarily focused on manually specifying resources and collecting high-quality data on specific domains, which significantly consume time and effort. To address this limitation, we propose an efficient data collection method $\textit{Query of CC}$ based on large language models. This method bootstraps seed information through a large language model and retrieves related data from public corpora. It not only collects knowledge-related data for specific domains but unearths the data with potential reasoning procedures. Through the application of this method, we have curated a high-quality dataset called KNOWLEDGE PILE, encompassing four major domains, including stem and humanities sciences, among others. Experimental results demonstrate that KNOWLEDGE PILE significantly improves the performance of large language models in mathematical and knowledge-related reasoning ability tests. To facilitate academic sharing, we open-source our dataset and code, providing valuable support to the academic community.
Toward Practical Automatic Speech Recognition and Post-Processing: a Call for Explainable Error Benchmark Guideline
Authors: Seonmin Koo, Chanjun Park, Jinsung Kim, Jaehyung Seo, Sugyeong Eo, Hyeonseok Moon, Heuiseok Lim
Date: 2024-01-26 00:00:00
Tasks: Automatic Speech Recognition, Automatic Speech Recognition (ASR), speech-recognition, Speech Recognition

Automatic speech recognition (ASR) outcomes serve as input for downstream tasks, substantially impacting the satisfaction level of end-users. Hence, the diagnosis and enhancement of the vulnerabilities present in the ASR model bear significant importance. However, traditional evaluation methodologies of ASR systems generate a singular, composite quantitative metric, which fails to provide comprehensive insight into specific vulnerabilities. This lack of detail extends to the post-processing stage, resulting in further obfuscation of potential weaknesses. Despite an ASR model's ability to recognize utterances accurately, subpar readability can negatively affect user satisfaction, giving rise to a trade-off between recognition accuracy and user-friendliness. To effectively address this, it is imperative to consider both the speech-level, crucial for recognition accuracy, and the text-level, critical for user-friendliness. Consequently, we propose the development of an Error Explainable Benchmark (EEB) dataset. This dataset, while considering both speech- and text-level, enables a granular understanding of the model's shortcomings. Our proposition provides a structured pathway for a more `real-world-centric' evaluation, a marked shift away from abstracted, traditional methods, allowing for the detection and rectification of nuanced system weaknesses, ultimately aiming for an improved user experience.
An Empirical Investigation of Domain Adaptation Ability for Chinese Spelling Check Models
Authors: Xi Wang, Ruoqing Zhao, Hongliang Dai, Piji Li
Date: 2024-01-26 00:00:00
Tasks: Domain Adaptation, Language Modeling, Language Modelling, Large Language Model

Chinese Spelling Check (CSC) is a meaningful task in the area of Natural Language Processing (NLP) which aims at detecting spelling errors in Chinese texts and then correcting these errors. However, CSC models are based on pretrained language models, which are trained on a general corpus. Consequently, their performance may drop when confronted with downstream tasks involving domain-specific terms. In this paper, we conduct a thorough evaluation about the domain adaption ability of various typical CSC models by building three new datasets encompassing rich domain-specific terms from the financial, medical, and legal domains. Then we conduct empirical investigations in the corresponding domain-specific test datasets to ascertain the cross-domain adaptation ability of several typical CSC models. We also test the performance of the popular large language model ChatGPT. As shown in our experiments, the performances of the CSC models drop significantly in the new domains.
T-Rex: Text-assisted Retrosynthesis Prediction
Authors: Yifeng Liu, Hanwen Xu, Tangqi Fang, Haocheng Xi, Zixuan Liu, Sheng Zhang, Hoifung Poon, Sheng Wang
Date: 2024-01-26 00:00:00
Tasks: Computational chemistry, Prediction, Re-Ranking, Retrosynthesis

As a fundamental task in computational chemistry, retrosynthesis prediction aims to identify a set of reactants to synthesize a target molecule. Existing template-free approaches only consider the graph structures of the target molecule, which often cannot generalize well to rare reaction types and large molecules. Here, we propose T-Rex, a text-assisted retrosynthesis prediction approach that exploits pre-trained text language models, such as ChatGPT, to assist the generation of reactants. T-Rex first exploits ChatGPT to generate a description for the target molecule and rank candidate reaction centers based both the description and the molecular graph. It then re-ranks these candidates by querying the descriptions for each reactants and examines which group of reactants can best synthesize the target molecule. We observed that T-Rex substantially outperformed graph-based state-of-the-art approaches on two datasets, indicating the effectiveness of considering text information. We further found that T-Rex outperformed the variant that only use ChatGPT-based description without the re-ranking step, demonstrate how our framework outperformed a straightforward integration of ChatGPT and graph information. Collectively, we show that text generated by pre-trained language models can substantially improve retrosynthesis prediction, opening up new avenues for exploiting ChatGPT to advance computational chemistry. And the codes can be found at https://github.com/lauyikfung/T-Rex.