user: You are a structured reasoning expert tasked with solving problems step by step. 
You first think about the reasoning process in the mind and then provide the answer. The reasoning process and answer should be enclosed within <think> </think> and <answer> </answer> tags, respectively, i.e., <think> reasoning process here </think> <answer> answer here </answer>. 
Given a question and the associated knowledge graph triplets (entity, relation, entity), you are asked to answer the question with these triplets and your own knowledge. 
You can break down the original question into several sub-questions and explore the given knowledge graph to solve them step-by-step. If there are multiple possible answers, choose one as the final answer. 
After thinking, when you finally reach a conclusion, clearly state the answer within <answer> </answer> tags, i.e., <answer> answer here </answer>. 
Question: name the medical trial that memantine has been tested for.? 
Knowledge Triplets: Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Placebo Control
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibile_genders, Male
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 5 tablet
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 10 tablet
Memantine hydrochloride 5 tablet, medicine.drug_formulation.formulation_of, Memantine
Memantine, medicine.drug.routed_drugs, Memantine Oral
Treatment, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Memantine hydrochloride 14 extended release capsule, medicine.drug_formulation.active_ingredient_moieties, Memantine
Blind experiment, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Parallel Assignment, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 21 extended release capsule
Memantine hydrochloride 28 extended release capsule, medicine.drug_formulation.formulation_of, Memantine
Placebo Control, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Safety/Efficacy Study
Memantine, medicine.medical_treatment.trials, Memantine in Systemic Lupus Erythematosus
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.clinicaltrials_identifier, NCT00181298
Memantine, medicine.drug.active_moieties, Memantine
Memantine hydrochloride 10 tablet, medicine.drug_formulation.active_ingredient_moieties, Memantine
Namenda, medicine.drug_brand.canonical_drug, Memantine
Forest Laboratories, Inc., medicine.medical_trial_sponsor.trials_sponsored, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug_ingredient.more_specific_ingredient, Memantine Hydrochloride
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.treatment_being_tested, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Treatment
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 5,10 kit
Memantine hydrochloride 21 extended release capsule, medicine.drug_formulation.formulation_of, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, History of non-compliance
Food and Drug Administration, medicine.medical_trial_health_authority.medical_trials, Memantine in Systemic Lupus Erythematosus
Memantine, chemistry.chemical_compound.pubchem_id, 4054
Alzheimer's disease, medicine.disease.treatments, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_inclusion_criteria, Clinical diagnosis of SLE
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.diseases, Systemic lupus erythematosus
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 21 extended release capsule
Systemic lupus erythematosus, medicine.disease.trials, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug.pregnancy_category, Pregnancy Category B (FDA)
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 28 extended release capsule
Memantine hydrochloride 2 solution, medicine.drug_formulation.formulation_of, Memantine
Memantine hydrochloride 7,14,21,28 kit, medicine.drug_formulation.formulation_of, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, Severe SLE flare in the last 6 weeks (defined as SLEDAI > 12 points)
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 2 solution
Memantine Hydrochloride, medicine.drug.active_moieties, Memantine
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 7 extended release capsule
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 2 solution
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, Current alcohol or illicit drug abuse
Memantine hydrochloride 5 tablet, medicine.drug_formulation.active_ingredient_moieties, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.sponsor, Johns Hopkins University
Nicotinic receptor antagonist, medicine.drug_class.drugs, Memantine
Randomized, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug.canonical_brands, Namenda
Memantine, chemistry.chemical_compound.average_molar_mass, 179.3
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 7,14,21,28 kit
Safety/Efficacy Study, medicine.medical_trial_design.trials, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug.drug_class, N-methyl-D-aspartate Receptor Antagonist
Memantine hydrochloride 28 extended release capsule, medicine.drug_formulation.active_ingredient_moieties, Memantine
Memantine hydrochloride 10 tablet, medicine.drug_formulation.formulation_of, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.type_of_trial, Interventional
Memantine Hydrochloride, medicine.drug_ingredient.more_general_ingredient, Memantine
Memantine, medicine.medical_treatment.used_to_treat, Alzheimer's disease
Memantine, chemistry.chemical_compound.inchikey, BUGYDGFZZOZRHP-UHFFFAOYSA-N
Memantine, medicine.medical_treatment.used_to_treat, Dementia
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 28 extended release capsule
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, Current use of Namenda, Aricept, Provigil
Memantine, medicine.drug.drug_class, 5-HT3 antagonist
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.end_date, 2007-05
Memantine, medicine.drug_ingredient.active_moiety_of_drug, Memantine Hydrochloride
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_inclusion_criteria, Self-reported cognitive impairment
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 7,14,21,28 kit
Memantine hydrochloride 7,14,21,28 kit, medicine.drug_formulation.active_ingredient_moieties, Memantine
N-methyl-D-aspartate Receptor Antagonist, medicine.drug_class.drugs, Memantine
NMDA receptor antagonist, medicine.drug_mechanism_of_action.drugs_with_this_mechanism_of_action, Memantine
Johns Hopkins University, medicine.medical_trial_sponsor.trials_sponsored, Memantine in Systemic Lupus Erythematosus
Memantine hydrochloride 5,10 kit, medicine.drug_formulation.active_ingredient_moieties, Memantine
NMDA receptor antagonist, medicine.drug_class.drugs, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibile_genders, Female
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Parallel Assignment
Memantine, base.schemastaging.context_name.common_name, Namenda
Memantine hydrochloride 21 extended release capsule, medicine.drug_formulation.active_ingredient_moieties, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.health_authority, Food and Drug Administration
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.primary_outcomes, Change in ANAM, Version 3.11
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 10 tablet
Memantine, medicine.drug.mechanism_of_action, NMDA receptor antagonist
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 5 tablet
Memantine, medicine.drug.drug_class, Nicotinic receptor antagonist
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.sponsor, Forest Laboratories, Inc.
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Blind experiment
Memantine hydrochloride 7 extended release capsule, medicine.drug_formulation.formulation_of, Memantine
Memantine hydrochloride 2 solution, medicine.drug_formulation.active_ingredient_moieties, Memantine
Memantine, chemistry.chemical_element.cas_id, 19982-08-2
Memantine, medicine.drug.atccode, N06DX01
Memantine, medicine.drug.drugbank, APRD00221
Memantine hydrochloride 5,10 kit, medicine.drug_formulation.formulation_of, Memantine
Interventional, medicine.medical_trial_type.medical_trials, Memantine in Systemic Lupus Erythematosus
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 5,10 kit
Pregnancy Category B (FDA), medicine.drug_pregnancy_category.drugs_in_this_category, Memantine
Memantine hydrochloride 14 extended release capsule, medicine.drug_formulation.formulation_of, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.location, Johns Hopkins University
Dementia, medicine.disease.treatments, Memantine
5-HT3 antagonist, medicine.drug_class.drugs, Memantine
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 14 extended release capsule
Memantine, medicine.drug.legal_status, Prescription drug
Memantine, medicine.drug.marketed_formulations, Memantine hydrochloride 7 extended release capsule
Memantine hydrochloride 7 extended release capsule, medicine.drug_formulation.active_ingredient_moieties, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, Pregnancy
Memantine, medicine.drug_ingredient.active_moiety_of_formulation, Memantine hydrochloride 14 extended release capsule
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.design, Randomized
Memantine Oral, medicine.routed_drug.routed_drug_of, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.start_date, 2006-03
Memantine, medicine.drug_ingredient.active_moiety_of_drug, Memantine
Memantine in Systemic Lupus Erythematosus, medicine.medical_trial.eligibility_exclusion_criteria, Liver or renal insufficiency/failure (calculated creatinine clearance < 50 cc/min)
Memantine, medicine.drug.drug_class, NMDA receptor antagonist
Memantine, user.avh.default_domain.ellerdale_topic.ellerdale_id, 0084-5159

Answer: Memantine in Systemic Lupus Erythematosus