I actually think Midtown is not the future, and that it lies further south.  The push has always been south.  The title companies, banks, and retailers largely left downtown several decades ago.  Look at how Dimond Abbott has filled in now, and then go sought to O'Malley/ Old Seward.  The money, the banks, the retailers, the restaurants, the wealth is all there or heading out there, until they hit the bottleneck (Potter's Marsh and the Mud.)