pt-sk/ml_research_abs huggingface dataset:
Four Types of Multiclass Frameworks for Pneumonia Classification and Its Validation in X-ray Scans Using Seven Types of Deep Learning Artificial Intelligence Models.
Authors: NoneNillmani, Pankaj KJain, NeerajSharma, Mannudeep KKalra, KlaudijaViskovic, LucaSaba, Jasjit SSuri
Journal: Diagnostics (Basel, Switzerland)

Background and Motivation: The novel coronavirus causing COVID-19 is exceptionally contagious, highly mutative, decimating human health and life, as well as the global economy, by consistent evolution of new pernicious variants and outbreaks. The reverse transcriptase polymerase chain reaction currently used for diagnosis has major limitations. Furthermore, the multiclass lung classification X-ray systems having viral, bacterial, and tubercular classes—including COVID-19—are not reliable. Thus, there is a need for a robust, fast, cost-effective, and easily available diagnostic method. Method: Artificial intelligence (AI) has been shown to revolutionize all walks of life, particularly medical imaging. This study proposes a deep learning AI-based automatic multiclass detection and classification of pneumonia from chest X-ray images that are readily available and highly cost-effective. The study has designed and applied seven highly efficient pre-trained convolutional neural networks—namely, VGG16, VGG19, DenseNet201, Xception, InceptionV3, NasnetMobile, and ResNet152—for classification of up to five classes of pneumonia. Results: The database consisted of 18,603 scans with two, three, and five classes. The best results were using DenseNet201, VGG16, and VGG16, respectively having accuracies of 99.84%, 96.7%, 92.67%; sensitivity of 99.84%, 96.63%, 92.70%; specificity of 99.84, 96.63%, 92.41%; and AUC of 1.0, 0.97, 0.92 (p < 0.0001 for all), respectively. Our system outperformed existing methods by 1.2% for the five-class model. The online system takes <1 s while demonstrating reliability and stability. Conclusions: Deep learning AI is a powerful paradigm for multiclass pneumonia classification.
Automatic Deep-Learning Segmentation of Epicardial Adipose Tissue from Low-Dose Chest CT and Prognosis Impact on COVID-19.
Authors: AxelBartoli, JorisFournel, LéaAit-Yahia, FarahCadour, FaroukTradi, BadihGhattas, SébastienCortaredona, MatthieuMillion, AdèleLasbleiz, AnneDutour, BénédicteGaborit, AlexisJacquier
Journal: Cells

Background: To develop a deep-learning (DL) pipeline that allowed an automated segmentation of epicardial adipose tissue (EAT) from low-dose computed tomography (LDCT) and investigate the link between EAT and COVID-19 clinical outcomes. Methods: This monocentric retrospective study included 353 patients: 95 for training, 20 for testing, and 238 for prognosis evaluation. EAT segmentation was obtained after thresholding on a manually segmented pericardial volume. The model was evaluated with Dice coefficient (DSC), inter-and intraobserver reproducibility, and clinical measures. Uni-and multi-variate analyzes were conducted to assess the prognosis value of the EAT volume, EAT extent, and lung lesion extent on clinical outcomes, including hospitalization, oxygen therapy, intensive care unit admission and death. Results: The mean DSC for EAT volumes was 0.85 ± 0.05. For EAT volume, the mean absolute error was 11.7 ± 8.1 cm3 with a non-significant bias of −4.0 ± 13.9 cm3 and a correlation of 0.963 with the manual measures (p < 0.01). The multivariate model providing the higher AUC to predict adverse outcome include both EAT extent and lung lesion extent (AUC = 0.805). Conclusions: A DL algorithm was developed and evaluated to obtain reproducible and precise EAT segmentation on LDCT. EAT extent in association with lung lesion extent was associated with adverse clinical outcomes with an AUC = 0.805.
Review of Machine Learning in Lung Ultrasound in COVID-19 Pandemic.
Authors: JingWang, XiaofengYang, BoranZhou, James JSohn, JunZhou, Jesse TJacob, Kristin AHiggins, Jeffrey DBradley, TianLiu
Journal: Journal of imaging

Ultrasound imaging of the lung has played an important role in managing patients with COVID-19-associated pneumonia and acute respiratory distress syndrome (ARDS). During the COVID-19 pandemic, lung ultrasound (LUS) or point-of-care ultrasound (POCUS) has been a popular diagnostic tool due to its unique imaging capability and logistical advantages over chest X-ray and CT. Pneumonia/ARDS is associated with the sonographic appearances of pleural line irregularities and B-line artefacts, which are caused by interstitial thickening and inflammation, and increase in number with severity. Artificial intelligence (AI), particularly machine learning, is increasingly used as a critical tool that assists clinicians in LUS image reading and COVID-19 decision making. We conducted a systematic review from academic databases (PubMed and Google Scholar) and preprints on arXiv or TechRxiv of the state-of-the-art machine learning technologies for LUS images in COVID-19 diagnosis. Openly accessible LUS datasets are listed. Various machine learning architectures have been employed to evaluate LUS and showed high performance. This paper will summarize the current development of AI for COVID-19 management and the outlook for emerging trends of combining AI-based LUS with robotics, telehealth, and other techniques.
Deep Learning-Based Classification of Reduced Lung Ultrasound Data From COVID-19 Patients.
Authors: UmairKhan, FedericoMento, LucreziaNicolussi Giacomaz, RiccardoTrevisan, AndreaSmargiassi, RiccardoInchingolo, TizianoPerrone, LibertarioDemi
Journal: IEEE transactions on ultrasonics, ferroelectrics, and frequency control

The application of lung ultrasound (LUS) imaging for the diagnosis of lung diseases has recently captured significant interest within the research community. With the ongoing COVID-19 pandemic, many efforts have been made to evaluate LUS data. A four-level scoring system has been introduced to semiquantitatively assess the state of the lung, classifying the patients. Various deep learning (DL) algorithms supported with clinical validations have been proposed to automate the stratification process. However, no work has been done to evaluate the impact on the automated decision by varying pixel resolution and bit depth, leading to the reduction in size of overall data. This article evaluates the performance of DL algorithm over LUS data with varying pixel and gray-level resolution. The algorithm is evaluated over a dataset of 448 LUS videos captured from 34 examinations of 20 patients. All videos are resampled by a factor of 2, 3, and 4 of original resolution, and quantized to 128, 64, and 32 levels, followed by score prediction. The results indicate that the automated scoring shows negligible variation in accuracy when it comes to the quantization of intensity levels only. Combined effect of intensity quantization with spatial down-sampling resulted in a prognostic agreement ranging from 73.5% to 82.3%.These results also suggest that such level of prognostic agreement can be achieved over evaluation of data reduced to 32 times of its original size. Thus, laying foundation to efficient processing of data in resource constrained environments.
Deep Learning and Medical Image Analysis for COVID-19 Diagnosis and Prediction.
Authors: TianmingLiu, EliotSiegel, DinggangShen
Journal: Annual review of biomedical engineering

The coronavirus disease 2019 (COVID-19) pandemic has imposed dramatic challenges to health-care organizations worldwide. To combat the global crisis, the use of thoracic imaging has played a major role in the diagnosis, prediction, and management of COVID-19 patients with moderate to severe symptoms or with evidence of worsening respiratory status. In response, the medical image analysis community acted quickly to develop and disseminate deep learning models and tools to meet the urgent need of managing and interpreting large amounts of COVID-19 imaging data. This review aims to not only summarize existing deep learning and medical image analysis methods but also offer in-depth discussions and recommendations for future investigations. We believe that the wide availability of high-quality, curated, and benchmarked COVID-19 imaging data sets offers the great promise of a transformative test bed to develop, validate, and disseminate novel deep learning methods in the frontiers of data science and artificial intelligence.
EDNC: Ensemble Deep Neural Network for COVID-19 Recognition.
Authors: LinYang, Shui-HuaWang, Yu-DongZhang
Journal: Tomography (Ann Arbor, Mich.)

The automatic recognition of COVID-19 diseases is critical in the present pandemic since it relieves healthcare staff of the burden of screening for infection with COVID-19. Previous studies have proven that deep learning algorithms can be utilized to aid in the diagnosis of patients with potential COVID-19 infection. However, the accuracy of current COVID-19 recognition models is relatively low. Motivated by this fact, we propose three deep learning architectures, F-EDNC, FC-EDNC, and O-EDNC, to quickly and accurately detect COVID-19 infections from chest computed tomography (CT) images. Sixteen deep learning neural networks have been modified and trained to recognize COVID-19 patients using transfer learning and 2458 CT chest images. The proposed EDNC has then been developed using three of sixteen modified pre-trained models to improve the performance of COVID-19 recognition. The results suggested that the F-EDNC method significantly enhanced the recognition of COVID-19 infections with 97.75% accuracy, followed by FC-EDNC and O-EDNC (97.55% and 96.12%, respectively), which is superior to most of the current COVID-19 recognition models. Furthermore, a localhost web application has been built that enables users to easily upload their chest CT scans and obtain their COVID-19 results automatically. This accurate, fast, and automatic COVID-19 recognition system will relieve the stress of medical professionals for screening COVID-19 infections.
CHS-Net: A Deep Learning Approach for Hierarchical Segmentation of COVID-19 via CT Images.
Authors: Narinder SinghPunn, SonaliAgarwal
Journal: Neural processing letters

The pandemic of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) also known as COVID-19 has been spreading worldwide, causing rampant loss of lives. Medical imaging such as computed tomography (CT), X-ray, etc., plays a significant role in diagnosing the patients by presenting the visual representation of the functioning of the organs. However, for any radiologist analyzing such scans is a tedious and time-consuming task. The emerging deep learning technologies have displayed its strength in analyzing such scans to aid in the faster diagnosis of the diseases and viruses such as COVID-19. In the present article, an automated deep learning based model, COVID-19 hierarchical segmentation network (CHS-Net) is proposed that functions as a semantic hierarchical segmenter to identify the COVID-19 infected regions from lungs contour via CT medical imaging using two cascaded residual attention inception U-Net (RAIU-Net) models. RAIU-Net comprises of a residual inception U-Net model with spectral spatial and depth attention network (SSD) that is developed with the contraction and expansion phases of depthwise separable convolutions and hybrid pooling (max and spectral pooling) to efficiently encode and decode the semantic and varying resolution information. The CHS-Net is trained with the segmentation loss function that is the defined as the average of binary cross entropy loss and dice loss to penalize false negative and false positive predictions. The approach is compared with the recently proposed approaches and evaluated using the standard metrics like accuracy, precision, specificity, recall, dice coefficient and Jaccard similarity along with the visualized interpretation of the model prediction with GradCam++ and uncertainty maps. With extensive trials, it is observed that the proposed approach outperformed the recently proposed approaches and effectively segments the COVID-19 infected regions in the lungs.
COVID-19 Identification System Using Transfer Learning Technique With Mobile-NetV2 and Chest X-Ray Images.
Authors: MahmoudRagab, SamahAlshehri, Gamil AbdelAzim, Hibah MAldawsari, AdeebNoor, JaberAlyami, SAbdel-Khalek
Journal: Frontiers in public health

Diagnosis is a crucial precautionary step in research studies of the coronavirus disease, which shows indications similar to those of various pneumonia types. The COVID-19 pandemic has caused a significant outbreak in more than 150 nations and has significantly affected the wellness and lives of many individuals globally. Particularly, discovering the patients infected with COVID-19 early and providing them with treatment is an important way of fighting the pandemic. Radiography and radiology could be the fastest techniques for recognizing infected individuals. Artificial intelligence strategies have the potential to overcome this difficulty. Particularly, transfer learning MobileNetV2 is a convolutional neural network architecture that can perform well on mobile devices. In this study, we used MobileNetV2 with transfer learning and augmentation data techniques as a classifier to recognize the coronavirus disease. Two datasets were used: the first consisted of 309 chest X-ray images (102 with COVID-19 and 207 were normal), and the second consisted of 516 chest X-ray images (102 with COVID-19 and 414 were normal). We assessed the model based on its sensitivity rate, specificity rate, confusion matrix, and F1-measure. Additionally, we present a receiver operating characteristic curve. The numerical simulation reveals that the model accuracy is 95.8% and 100% at dropouts of 0.3 and 0.4, respectively. The model was implemented using Keras and Python programming.
MultiR-Net: A Novel Joint Learning Network for COVID-19 segmentation and classification.
Authors: Cheng-FanLi, Yi-DuoXu, Xue-HaiDing, Jun-JuanZhao, Rui-QiDu, Li-ZhongWu, Wen-PingSun
Journal: Computers in biology and medicine

The outbreak of COVID-19 has caused a severe shortage of healthcare resources. Ground Glass Opacity (GGO) and consolidation of chest CT scans have been an essential basis for imaging diagnosis since 2020. The similarity of imaging features between COVID-19 and other pneumonia makes it challenging to distinguish between them and affects radiologists' diagnosis. Recently, deep learning in COVID-19 has been mainly divided into disease classification and lesion segmentation, yet little work has focused on the feature correlation between the two tasks. To address these issues, in this study, we propose MultiR-Net, a 3D deep learning model for combined COVID-19 classification and lesion segmentation, to achieve real-time and interpretable COVID-19 chest CT diagnosis. Precisely, the proposed network consists of two subnets: a multi-scale feature fusion UNet-like subnet for lesion segmentation and a classification subnet for disease diagnosis. The features between the two subnets are fused by the reverse attention mechanism and the iterable training strategy. Meanwhile, we proposed a loss function to enhance the interaction between the two subnets. Individual metrics can not wholly reflect network effectiveness. Thus we quantify the segmentation results with various evaluation metrics such as average surface distance, volume Dice, and test on the dataset. We employ a dataset containing 275 3D CT scans for classifying COVID-19, Community-acquired Pneumonia (CAP), and healthy people and segmented lesions in pneumonia patients. We split the dataset into 70% and 30% for training and testing. Extensive experiments showed that our multi-task model framework obtained an average recall of 93.323%, an average precision of 94.005% on the classification test set, and a 69.95% Volume Dice score on the segmentation test set of our dataset.
COVID-19 image classification using deep learning: Advances, challenges and opportunities.
Authors: PriyaAggarwal, Narendra KumarMishra, BinishFatimah, PushpendraSingh, AnubhaGupta, Shiv DuttJoshi
Journal: Computers in biology and medicine

Corona Virus Disease-2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2), is a highly contagious disease that has affected the lives of millions around the world. Chest X-Ray (CXR) and Computed Tomography (CT) imaging modalities are widely used to obtain a fast and accurate diagnosis of COVID-19. However, manual identification of the infection through radio images is extremely challenging because it is time-consuming and highly prone to human errors. Artificial Intelligence (AI)-techniques have shown potential and are being exploited further in the development of automated and accurate solutions for COVID-19 detection. Among AI methodologies, Deep Learning (DL) algorithms, particularly Convolutional Neural Networks (CNN), have gained significant popularity for the classification of COVID-19. This paper summarizes and reviews a number of significant research publications on the DL-based classification of COVID-19 through CXR and CT images. We also present an outline of the current state-of-the-art advances and a critical discussion of open challenges. We conclude our study by enumerating some future directions of research in COVID-19 imaging classification.
INASNET: Automatic identification of coronavirus disease (COVID-19) based on chest X-ray using deep neural network.
Authors: MurukessanPerumal, AkshayNayak, R PraneethaSree, MSrinivas
Journal: ISA transactions

Testing is one of the important methodologies used by various countries in order to fight against COVID-19 infection. The infection is considered as one of the deadliest ones although the mortality rate is not very high. COVID-19 infection is being caused by SARS-CoV2 which is termed as severe acute respiratory syndrome coronavirus 2 virus. To prevent the community, transfer among the masses, testing plays an important role. Efficient and quicker testing techniques helps in identification of infected person which makes it easier for to isolate the patient. Deep learning methods have proved their presence and effectiveness in medical image analysis and in the identification of some of the diseases like pneumonia. Authors have been proposed a deep learning mechanism and system to identify the COVID-19 infected patient on analyzing the X-ray images. Symptoms in the COVID-19 infection is well similar to the symptoms occurring in the influenza and pneumonia. The proposed model Inception Nasnet (INASNET) is being able to separate out and classify the X-ray images in the corresponding normal, COVID-19 infected or pneumonia infected classes. This testing method will be a boom for the doctors and for the state as it is a way cheaper method as compared to the other testing kits used by the healthcare workers for the diagnosis of the disease. Continuous analysis by convolutional neural network and regular evaluation will result in better accuracy and helps in eliminating the false-negative results. INASNET is based on the combined platform of InceptionNet and Neural network architecture search which will result in having higher and faster predictions. Regular testing, faster results, economically viable testing using X-ray images will help the front line workers to make a win over COVID-19.
Metaheuristics based COVID-19 detection using medical images: A review.
Authors: MamoonaRiaz, MaryamBashir, IrfanYounas
Journal: Computers in biology and medicine

Many countries in the world have been facing the rapid spread of COVID-19 since February 2020. There is a dire need for efficient and cheap automated diagnosis systems that can reduce the pressure on healthcare systems. Extensive research is being done on the use of image classification for the detection of COVID-19 through X-ray and CT-scan images of patients. Deep learning has been the most popular technique for image classification during the last decade. However, the performance of deep learning-based methods heavily depends on the architecture of the deep neural network. Over the last few years, metaheuristics have gained popularity for optimizing the architecture of deep neural networks. Metaheuristics have been widely used to solve different complex non-linear optimization problems due to their flexibility, simplicity, and problem independence. This paper aims to study the different image classification techniques for chest images, including the applications of metaheuristics for optimization and feature selection of deep learning and machine learning models. The motivation of this study is to focus on applications of different types of metaheuristics for COVID-19 detection and to shed some light on future challenges in COVID-19 detection from medical images. The aim is to inspire researchers to focus their research on overlooked aspects of COVID-19 detection.
Efficacy of Transfer Learning-based ResNet models in Chest X-ray image classification for detecting COVID-19 Pneumonia.
Authors: SadiaShowkat, ShaimaQureshi
Journal: Chemometrics and intelligent laboratory systems : an international journal sponsored by the Chemometrics Society

Because of COVID-19's effect on pulmonary tissues, Chest X-ray(CXR) and Computed Tomography (CT) images have become the preferred imaging modality for detecting COVID-19 infections at the early diagnosis stages, particularly when the symptoms are not specific. A significant fraction of individuals with COVID-19 have negative polymerase chain reaction (PCR) test results; therefore, imaging studies coupled with epidemiological, clinical, and laboratory data assist in the decision making. With the newer variants of COVID-19 emerging, the burden on diagnostic laboratories has increased manifold. Therefore, it is important to employ beyond laboratory measures to solve complex CXR image classification problems. One such tool is Convolutional Neural Network (CNN), one of the most dominant Deep Learning (DL) architectures. DL entails training a CNN for a task such as classification using extensive datasets. However, the labelled data for COVID-19 is scarce, proving to be a prime impediment to applying DL-assisted analysis. The available datasets are either scarce or too diversified to learn effective feature representations; therefore Transfer Learning (TL) approach is utilized. TL-based ResNet architecture has a powerful representational ability, making it popular in Computer Vision. The aim of this study is two-fold- firstly, to assess the performance of ResNet models for classifying Pneumonia cases from CXR images and secondly, to build a customized ResNet model and evaluate its contribution to the performance improvement. The global accuracies achieved by the five models i.e., ResNet18_v1, ResNet34_v1, ResNet50_v1, ResNet101_v1, ResNet152_v1 are 91.35%, 90.87%, 92.63%, 92.95%, and 92.95% respectively. ResNet50_v1 displayed the highest sensitivity of 97.18%, ResNet101_v1 showed the specificity of 94.02%, and ResNet18_v1 had the highest precision of 93.53%. The findings are encouraging, demonstrating the effectiveness of ResNet in the automatic detection of Pneumonia for COVID-19 diagnosis. The customized ResNet model presented in this study achieved 95% global accuracy, 95.65% precision, 92.74% specificity, and 95.9% sensitivity, thereby allowing a reliable analysis of CXR images to facilitate the clinical decision-making process. All simulations were carried in PyTorch utilizing Quadro 4000 GPU with Intel(R) Xeon(R) CPU E5-1650 v4 @ 3.60 ​GHz processor and 63.9 ​GB useable RAM.