pt-sk/ml_research_abs huggingface dataset:
Wavelet and deep learning-based detection of SARS-nCoV from thoracic X-ray images for rapid and efficient testing.
Authors: Amar KumarVerma, InturiVamsi, PrernaSaurabh, RadhikaSudha, SabareeshG R, RajkumarS
Journal: Expert systems with applications

This paper proposes a wavelet and artificial intelligence-enabled rapid and efficient testing procedure for patients with Severe Acute Respiratory Coronavirus Syndrome (SARS-nCoV) through a deep learning approach from thoracic X-ray images. Presently, the virus infection is diagnosed primarily by a process called the real-time Reverse Transcriptase-Polymerase Chain Reaction (rRT-PCR) based on its genetic prints. This whole procedure takes a substantial amount of time to identify and diagnose the patients infected by the virus. The proposed research uses a wavelet-based convolution neural network architectures to detect SARS-nCoV. CNN is pre-trained on the ImageNet and trained end-to-end using thoracic X-ray images. To execute Discrete Wavelet Transforms (DWT), the available mother wavelet functions from different families, namely Haar, Daubechies, Symlet, Biorthogonal, Coiflet, and Discrete Meyer, were considered. Two-level decomposition via DWT is adopted to extract prominent features peripheral and subpleural ground-glass opacities, often in the lower lobes explicitly from thoracic X-ray images to suppress noise effect, further enhancing the signal to noise ratio. The proposed wavelet-based deep learning models of both, two-class instances (COVID vs. Normal) and four-class instances (COVID-19 vs. PNA bacterial vs. PNA viral vs. Normal) were validated from publicly available databases using k-Fold Cross Validation (k-Fold CV) technique. In addition to these X-ray images, images of recent COVID-19 patients were further used to examine the model's practicality and real-time feasibility in combating the current pandemic situation. It was observed that the Symlet 7 approximation component with two-level manifested the highest test accuracy of 98.87%, followed by Biorthogonal 2.6 with an efficiency of 98.73%. While the test accuracy for Symlet 7 and Biorthogonal 2.6 is high, Haar and Daubechies with two levels have demonstrated excellent validation accuracy on unseen data. It was also observed that the precision, the recall rate, and the dice similarity coefficient for four-class instances were 98%, 98%, and 99%, respectively, using the proposed algorithm.
Fully automated unified prognosis of Covid-19 chest X-ray/CT scan images using Deep Covix-Net model.
Authors: Dasari NagaVinod, B RebeccaJeyavadhanam, Adamu MurtalaZungeru, S R SPrabaharan
Journal: Computers in biology and medicine

SARS-COV2 (Covid-19) prevails in the form of multiple mutant variants causing pandemic situations around the world. Thus, medical diagnosis is not accurate. Although several clinical diagnostic methodologies have been introduced hitherto, chest X-ray and computed tomography (CT) imaging techniques complement the analytical methods (for instance, RT-PCR) to a certain extent. In this context, we demonstrate a novel framework by employing various image segmentation models to leverage the available image databases (9000 chest X-ray images and 6000 CT scan images). The proposed methodology is expected to assist in the prognosis of Covid-19-infected individuals through examination of chest X-rays and CT scans of images using the Deep Covix-Net model for identifying novel coronavirus-infected patients effectively and efficiently. The slice of the precision score is analysed in terms of performance metrics such as accuracy, the confusion matrix, and the receiver operating characteristic curve. The result leans on the database obtainable in the GitHub and Kaggle repository, conforming to their endorsed chest X-ray and CT images. The classification performances of various algorithms were examined for a test set with 1800 images. The proposed model achieved a 96.8% multiple-classification accuracy among Covid-19, normal, and pneumonia chest X-ray databases. Moreover, it attained a 97% accuracy among Covid-19 and normal CT scan images. Thus, the proposed mechanism achieves the rigorousness associated with the machine learning technique, providing rapid outcomes for both training and testing datasets.
CoLe-CNN+: Context learning - Convolutional neural network for COVID-19-Ground-Glass-Opacities detection and segmentation.
Authors: GiuseppePezzano, OliverDíaz, Vicent RibasRipoll, PetiaRadeva
Journal: Computers in biology and medicine

The most common tool for population-wide COVID-19 identification is the Reverse Transcription-Polymerase Chain Reaction test that detects the presence of the virus in the throat (or sputum) in swab samples. This test has a sensitivity between 59% and 71%. However, this test does not provide precise information regarding the extension of the pulmonary infection. Moreover, it has been proven that through the reading of a computed tomography (CT) scan, a clinician can provide a more complete perspective of the severity of the disease. Therefore, we propose a comprehensive system for fully-automated COVID-19 detection and lesion segmentation from CT scans, powered by deep learning strategies to support decision-making process for the diagnosis of COVID-19.
In the workflow proposed, the input CT image initially goes through lung delineation, then COVID-19 detection and finally lesion segmentation. The chosen neural network has a U-shaped architecture using a newly introduced Multiple Convolutional Layers structure, that produces a lung segmentation mask within a novel pipeline for direct COVID-19 detection and segmentation. In addition, we propose a customized loss function that guarantees an optimal balance on average between sensitivity and precision.
Lungs' segmentation results show a sensitivity near 99% and Dice-score of 97%. No false positives were observed in the detection network after 10 different runs with an average accuracy of 97.1%. The average accuracy for lesion segmentation was approximately 99%. Using UNet as a benchmark, we compared our results with several other techniques proposed in the literature, obtaining the largest improvement over the UNet outcomes.
The method proposed in this paper outperformed the state-of-the-art methods for COVID-19 lesion segmentation from CT images, and improved by 38.2% the results for F1-score of UNet. The high accuracy observed in this work opens up a wide range of possible applications of our algorithm in other fields related to medical image segmentation.
COVID-19 diagnosis and severity detection from CT-images using transfer learning and back propagation neural network.
Authors: AswathyA L, Anand HareendranS, Vinod ChandraS S
Journal: Journal of infection and public health

COVID-19 diagnosis in symptomatic patients is an important factor for arranging the necessary lifesaving facilities like ICU care and ventilator support. For this purpose, we designed a computer-aided diagnosis and severity detection method by using transfer learning and a back propagation neural network.
To increase the learning capability, we used data augmentation. Most of the previously done works in this area concentrate on private datasets, but we used two publicly available datasets. The first section diagnose COVID-19 from the input CT image using the transfer learning of the pre-trained network ResNet-50. We used ResNet-50 and DenseNet-201 pre-trained networks for feature extraction and trained a back propagation neural network to classify it into High, Medium, and Low severity.
The proposed method for COVID-19 diagnosis gave an accuracy of 98.5% compared with the state-of-the-art methods. The experimental evaluation shows that combining the ResNet-50 and DenseNet-201 features gave more accurate results with the test data. The proposed system for COVID-19 severity detection gave better average classification accuracy of 97.84% compared with the state-of-the-art methods. This enables medical practitioners to identify the resources and treatment plans correctly.
This work is useful in the medical field as a first-line severity risk detection that is helpful for medical personnel to plan patient care and assess the need for ICU facilities and ventilator support. A computer-aided system that is helpful to make a care plan for the huge amount of patient inflow each day is sure to be an asset in these turbulent times.
Automatic COVID-19 Detection Using Exemplar Hybrid Deep Features with X-ray Images.
Authors: Prabal DattaBarua, Nadia FareedaMuhammad Gowdh, KartiniRahmat, NorlisahRamli, Wei LinNg, Wai YeeChan, MutluKuluozturk, SengulDogan, MehmetBaygin, OrhanYaman, TurkerTuncer, TaoWen, Kang HaoCheong, U RajendraAcharya
Journal: International journal of environmental research and public health

COVID-19 and pneumonia detection using medical images is a topic of immense interest in medical and healthcare research. Various advanced medical imaging and machine learning techniques have been presented to detect these respiratory disorders accurately. In this work, we have proposed a novel COVID-19 detection system using an exemplar and hybrid fused deep feature generator with X-ray images. The proposed Exemplar COVID-19FclNet9 comprises three basic steps: exemplar deep feature generation, iterative feature selection and classification. The novelty of this work is the feature extraction using three pre-trained convolutional neural networks (CNNs) in the presented feature extraction phase. The common aspects of these pre-trained CNNs are that they have three fully connected layers, and these networks are AlexNet, VGG16 and VGG19. The fully connected layer of these networks is used to generate deep features using an exemplar structure, and a nine-feature generation method is obtained. The loss values of these feature extractors are computed, and the best three extractors are selected. The features of the top three fully connected features are merged. An iterative selector is used to select the most informative features. The chosen features are classified using a support vector machine (SVM) classifier. The proposed COVID-19FclNet9 applied nine deep feature extraction methods by using three deep networks together. The most appropriate deep feature generation model selection and iterative feature selection have been employed to utilise their advantages together. By using these techniques, the image classification ability of the used three deep networks has been improved. The presented model is developed using four X-ray image corpora (DB1, DB2, DB3 and DB4) with two, three and four classes. The proposed Exemplar COVID-19FclNet9 achieved a classification accuracy of 97.60%, 89.96%, 98.84% and 99.64% using the SVM classifier with 10-fold cross-validation for four datasets, respectively. Our developed Exemplar COVID-19FclNet9 model has achieved high classification accuracy for all four databases and may be deployed for clinical application.
Learning-to-augment strategy using noisy and denoised data: Improving generalizability of deep CNN for the detection of COVID-19 in X-ray images.
Authors: MohammadMomeny, Ali AsgharNeshat, Mohammad ArafatHussain, SolmazKia, MahmoudMarhamati, AhmadJahanbakhshi, GhassanHamarneh
Journal: Computers in biology and medicine

Chest X-ray images are used in deep convolutional neural networks for the detection of COVID-19, the greatest human challenge of the 21st century. Robustness to noise and improvement of generalization are the major challenges in designing these networks. In this paper, we introduce a strategy for data augmentation using the determination of the type and value of noise density to improve the robustness and generalization of deep CNNs for COVID-19 detection. Firstly, we present a learning-to-augment approach that generates new noisy variants of the original image data with optimized noise density. We apply a Bayesian optimization technique to control and choose the optimal noise type and its parameters. Secondly, we propose a novel data augmentation strategy, based on denoised X-ray images, that uses the distance between denoised and original pixels to generate new data. We develop an autoencoder model to create new data using denoised images corrupted by the Gaussian and impulse noise. A database of chest X-ray images, containing COVID-19 positive, healthy, and non-COVID pneumonia cases, is used to fine-tune the pre-trained networks (AlexNet, ShuffleNet, ResNet18, and GoogleNet). The proposed method performs better results compared to the state-of-the-art learning to augment strategies in terms of sensitivity (0.808), specificity (0.915), and F-Measure (0.737). The source code of the proposed method is available at https://github.com/mohamadmomeny/Learning-to-augment-strategy.
Automated Diagnosis of COVID-19 Using Deep Supervised Autoencoder With Multi-View Features From CT Images.
Authors: JianhongCheng, WeiZhao, JinLiu, XingzhiXie, ShangjieWu, LiangliangLiu, HailinYue, JunjianLi, JianxinWang, JunLiu
Journal: IEEE/ACM transactions on computational biology and bioinformatics

Accurate and rapid diagnosis of coronavirus disease 2019 (COVID-19) from chest CT scans is of great importance and urgency during the worldwide outbreak. However, radiologists have to distinguish COVID-19 pneumonia from other pneumonia in a large number of CT scans, which is tedious and inefficient. Thus, it is urgently and clinically needed to develop an efficient and accurate diagnostic tool to help radiologists to fulfill the difficult task. In this study, we proposed a deep supervised autoencoder (DSAE) framework to automatically identify COVID-19 using multi-view features extracted from CT images. To fully explore features characterizing CT images from different frequency domains, DSAE was proposed to learn the latent representation by multi-task learning. The proposal was designed to both encode valuable information from different frequency features and construct a compact class structure for separability. To achieve this, we designed a multi-task loss function, which consists of a supervised loss and a reconstruction loss. Our proposed method was evaluated on a newly collected dataset of 787 subjects including COVID-19 pneumonia patients, other pneumonia patients, and normal subjects without abnormal CT findings. Extensive experimental results demonstrated that our proposed method achieved encouraging diagnostic performance and may have potential clinical application for the diagnosis of COVID-19.
Coronavirus disease analysis using chest X-ray images and a novel deep convolutional neural network.
Authors: Saddam HussainKhan, AnabiaSohail, Muhammad MohsinZafar, AsifullahKhan
Journal: Photodiagnosis and photodynamic therapy

The recent emergence of a highly infectious and contagious respiratory viral disease known as COVID-19 has vastly impacted human lives and overloaded the health care system. Therefore, it is crucial to develop a fast and accurate diagnostic system for the timely identification of COVID-19 infected patients and thus to help control its spread.
This work proposes a new deep CNN based technique for COVID-19 classification in X-ray images. In this regard, two novel custom CNN architectures, namely COVID-RENet-1 and COVID-RENet-2, are developed for COVID-19 specific pneumonia analysis. The proposed technique systematically employs Region and Edge-based operations along with convolution operations. The advantage of the proposed idea is validated by performing series of experimentation and comparing results with two baseline CNNs that exploited either a single type of pooling operation or strided convolution down the architecture. Additionally, the discrimination capacity of the proposed technique is assessed by benchmarking it against the state-of-the-art CNNs on radiologist's authenticated chest X-ray dataset. Implementation is available at https://github.com/PRLAB21/Coronavirus-Disease-Analysis-using-Chest-X-Ray-Images.
The proposed classification technique shows good generalization as compared to existing CNNs by achieving promising MCC (0.96), F-score (0.98) and Accuracy (98%). This suggests that the idea of synergistically using Region and Edge-based operations aid in better exploiting the region homogeneity, textural variations, and region boundary-related information in an image, which helps to capture the pneumonia specific pattern.
The encouraging results of the proposed classification technique on the test set with high sensitivity (0.98) and precision (0.98) suggest the effectiveness of the proposed technique. Thus, it suggests the potential use of the proposed technique in other X-ray imagery-based infectious disease analysis.
Role of deep learning in early detection of COVID-19: Scoping review.
Authors: MahmoodAlzubaidi, Haider DhiaZubaydi, Ali AbdulqaderBin-Salem, Alaa AAbd-Alrazaq, ArfanAhmed, MowafaHouseh
Journal: Computer methods and programs in biomedicine update

Since the onset of the COVID-19 pandemic, the world witnessed disruption on an unprecedented scale affecting our daily lives including but not limited to healthcare, business, education, and transportation. Deep Learning (DL) is a branch of Artificial intelligence (AI) applications, the recent growth of DL includes features that could be helpful in fighting the COVID-19 pandemic. Utilizing such features could support public health efforts.
Investigate the literature available in the use of DL technology to support dealing with the COVID-19 crisis. We summarize the literature that uses DL features to analyze datasets for the purpose of a quick COVID-19 detection.
This review follows PRISMA Extension for Scoping Reviews (PRISMA-ScR). We have scanned the most two commonly used databases (IEEE, ACM). Search terms were identified based on the target intervention (DL) and the target population (COVID-19). Two authors independently handled study selection and one author assigned for data extraction. A narrative approach is used to synthesize the extracted data.
We retrieved 53 studies and after passing through PRISMA excluding criteria, only 17 studies are considered in this review. All studies used deep learning for detection of COVID-19 cases in early stage based on different diagnostic modalities. Convolutional Neural Network (CNN) and Transfer Learning (TL) were the most commonly used techniques.
The included studies showed that DL techniques has significant impact on early detection of COVID-19 with high accuracy rate. However, most of the proposed methods are still in development and not tested in a clinical setting. Further investigation and collaboration are required from the research community and healthcare professionals in order to develop and standardize guidelines for use of DL in the healthcare domain.
Artificial intelligence-driven assessment of radiological images for COVID-19.
Authors: YassineBouchareb, PegahMoradi Khaniabadi, FaizaAl Kindi, HumoudAl Dhuhli, IsaacShiri, HabibZaidi, ArmanRahmim
Journal: Computers in biology and medicine

Artificial Intelligence (AI) methods have significant potential for diagnosis and prognosis of COVID-19 infections. Rapid identification of COVID-19 and its severity in individual patients is expected to enable better control of the disease individually and at-large. There has been remarkable interest by the scientific community in using imaging biomarkers to improve detection and management of COVID-19. Exploratory tools such as AI-based models may help explain the complex biological mechanisms and provide better understanding of the underlying pathophysiological processes. The present review focuses on AI-based COVID-19 studies as applies to chest x-ray (CXR) and computed tomography (CT) imaging modalities, and the associated challenges. Explicit radiomics, deep learning methods, and hybrid methods that combine both deep learning and explicit radiomics have the potential to enhance the ability and usefulness of radiological images to assist clinicians in the current COVID-19 pandemic. The aims of this review are: first, to outline COVID-19 AI-analysis workflows, including acquisition of data, feature selection, segmentation methods, feature extraction, and multi-variate model development and validation as appropriate for AI-based COVID-19 studies. Secondly, existing limitations of AI-based COVID-19 analyses are discussed, highlighting potential improvements that can be made. Finally, the impact of AI and radiomics methods and the associated clinical outcomes are summarized. In this review, pipelines that include the key steps for AI-based COVID-19 signatures identification are elaborated. Sample size, non-standard imaging protocols, segmentation, availability of public COVID-19 databases, combination of imaging and clinical information and full clinical validation remain major limitations and challenges. We conclude that AI-based assessment of CXR and CT images has significant potential as a viable pathway for the diagnosis, follow-up and prognosis of COVID-19.
COVID TV-Unet: Segmenting COVID-19 chest CT images using connectivity imposed Unet.
Authors: NargesSaeedizadeh, ShervinMinaee, RaheleKafieh, ShakibYazdani, MilanSonka
Journal: Computer methods and programs in biomedicine update

The novel corona-virus disease (COVID-19) pandemic has caused a major outbreak in more than 200 countries around the world, leading to a severe impact on the health and life of many people globally. By October 2020, more than 44 million people were infected, and more than 1,000,000 deaths were reported. Computed Tomography (CT) images can be used as an alternative to the time-consuming RT-PCR test, to detect COVID-19. In this work we propose a segmentation framework to detect chest regions in CT images, which are infected by COVID-19. An architecture similar to a Unet model was employed to detect ground glass regions on a voxel level. As the infected regions tend to form connected components (rather than randomly distributed voxels), a suitable regularization term based on 2D-anisotropic total-variation was developed and added to the loss function. The proposed model is therefore called "TV-Unet". Experimental results obtained on a relatively large-scale CT segmentation dataset of around 900 images, incorporating this new regularization term leads to a 2% gain on overall segmentation performance compared to the Unet trained from scratch. Our experimental analysis, ranging from visual evaluation of the predicted segmentation results to quantitative assessment of segmentation performance (precision, recall, Dice score, and mIoU) demonstrated great ability to identify COVID-19 associated regions of the lungs, achieving a mIoU rate of over 99%, and a Dice score of around 86%.
Deep Transfer Learning-Based Framework for COVID-19 Diagnosis Using Chest CT Scans and Clinical Information.
Authors: ShreyasMishra
Journal: SN computer science

The Coronavirus Disease 2019 (COVID-19) which first emerged in Wuhan, China in late December, 2019, has now spread to all the countries in the world. Conventional testing methods such as the antigen test, serology tests, and polymerase chain reaction tests are widely used. However, the test results can take anything from a few hours to a few days to reach the patient. Chest CT scan images have been used as alternatives for the detection of COVID-19 infection. Use of CT scan images alone might have limited capabilities, which calls attention to incorporating clinical features. In this paper, deep learning algorithms have been utilized to integrate the chest CT scan images obtained from patients with their clinical characteristics for fast and accurate diagnosis of COVID-19 patients. The framework uses an ANN to obtain the probability of the patient being infected with COVID-19 using their clinical information. Beyond a certain threshold, the chest CT scan of the patient is classified using a deep learning model which has been trained to classify the CT scan with 99% accuracy.