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In this task, you are given a abstract of article and corresponding title of an article. Your task is to generate label "yes" if title is right for article, otherwise generate "no".

Abstract: The recommended treatment for patients with chronic hepatitis C, pegylated interferon- (PEG-IFN-) plus ribavirin (RBV), does not provide sustained virologic response (SVR) in all patients. We report a genome-wide association study (GWAS) to null virological response (NVR) in the treatment of patients with hepatitis C virus (HCV) genotype 1 within a Japanese population. We found two SNPs near the gene IL28B on chromosome 19 to be strongly associated with NVR (rs12980275, P = 1.93 1013, and rs8099917, 3.11 1015). We replicated these associations in an independent cohort (combined P values, 2.84 1027 (OR = 17.7; 95% CI = 10.031.3) and 2.68 1032 (OR = 27.1; 95% CI = 14.650.3), respectively). Compared to NVR, these SNPs were also associated with SVR (rs12980275, P = 3.99 1024, and rs8099917, P = 1.11 1027). In further fine mapping of the region, seven SNPs (rs8105790, rs11881222, rs8103142, rs28416813, rs4803219, rs8099917 and rs7248668) located in the IL28B region showed the most significant associations (P = 5.52 10282.68 1032; OR = 22.327.1). Real-time quantitative PCR assays in peripheral blood mononuclear cells showed lower IL28B expression levels in individuals carrying the minor alleles (P = 0.015).. Title: Genome-wide association of IL28B with response to pegylated interferon- and ribavirin therapy for chronic hepatitis C
Output:
yes