Instructions: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Input: Question: Does stat3 signaling activation crosslinking of TGF-1 in hepatic stellate cell exacerbate liver injury and fibrosis?
Answer: We provide a novel role of Stat3 cooperating TGF-1 in activation and anti-apoptotic effect of HSCs. Stat3 worsens liver fibrosis through the up-regulation of TGF-1 and fibrotic product expression.
Output:
yes