In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Example Input: Paragraph: Viruses, the molecular nanomachines infecting hosts ranging from prokaryotes to eukaryotes, come in different sizes, shapes and symmetries. Questions such as what principles govern their structural organization, what factors guide their assembly, how these viruses integrate multifarious functions into one unique structure have enamored researchers for years. In the last five decades, following Caspar and Klug's elegant conceptualization of how viruses are constructed, high resolution structural studies using X-ray crystallography and more recently cryo-EM techniques have provided a wealth of information on structures of variety of viruses. These studies have significantly furthered our understanding of the principles that underlie structural organization in viruses. Such an understanding has practical impact in providing a rational basis for the design and development of antiviral strategies. In this chapter, we review principles underlying capsid formation in a variety of viruses, emphasizing the recent developments along with some historical perspective. -barrel fold; HK97-like fold; Double -barrel trimer Often the size of the virus is proportional to the size of the genome. However, the viral genome contributes far less to the total mass of the virion than the capsid proteins. It was NIH Public Access
Title: Principles of Virus Structural Organization
Example Output: True

Example Input: Paragraph: Rapid diagnosis of adenoviral respiratory infections is required in order to decide optimal treatment strategies. The adenovirus antigen immunochromatography Adeno Respiratory Card Letitest (Leti diagnostics, Barcelona, Spain), was evaluated versus the shell-vial culture and multiplex PCR (Clart Pneumovir Version 3.0, Genomica, Madrid, Spain), in nasopharyngeal washes and oropharyngeal swabs specimens from subjects with respiratory tract infections. Between April 2011 and November 2012, 224 patients were included. The IC Adeno Respiratory Card Letitest was positive for 77.9% (74 of 95) of patients diagnosed at bedside. Using multiplex-PCR as the reference standard, the overall sensitivity was 77.9% and the specificity was 73.6%. Taking shell-viral culture as the reference method, the Adeno Respiratory Card Letitest (Leti diagnostics, Barcelona, Spain) sensitivity and specificity values were 80.0% and 60.9%, respectively. Using RT-PCR (Clart Pneumovir Version 3.0, Genomica, Madrid, Spain) as the reference standard, the viral culture sensitivity was 53.2% and the specificity was 100%. The Adeno Respiratory Card Letitest (Leti diagnostics, Barcelona, Spain) assay could be a simple and rapid method for antigenic detection of adenovirus in pediatric respiratory samples although it would be necessary to improve the specificity and sensitivity of the test.
Title: Immunochromatographic test for detection of adenovirus from respiratory samples: Is it a real solution for pediatric emergency department?
Example Output: True

Example Input: Paragraph: Simulating epidemics in metapopulations is a challenging issue due to the large demographic and geographic scales to incorporate. Traditional epidemiologic models choose to simplify reality by ignoring both the spatial distribution of populations and possible intrapopulation heterogeneities, whereas more recent solutions based on Individual-Based Modeling (IBM) can achieve high precision but are costly to compute and analyze. We introduce here an original alternative to these two approaches, which relies on a novel hybrid modeling framework and incarnates a multiscale view of epidemics. The model relies on a technical fusion of two modeling paradigms: System Dynamics (SD) and Individual-Based Modeling. It features an aggregated representation of local outbreaks rendered in SD, and at the same time a spatially-explicit simulation of the spread between populations simulated in IBM. We first present the design of this deterministic model, show that it can reproduce the dynamics of real resurgent epidemics, and infer from the sensitivity of several spatial factors absent in compartmental models the importance of having large-scale epidemiological processes represented inside of an explicitly disaggregated metapopulation. After discussing the implications of results obtained from simulation runs and the applicability of this model, we conclude that SD-IB hybrid modeling can be an interesting choice to represent epidemics in a spatially-explicit way without necessarily taking into account individual heterogeneities, and therefore it can be considered as a valuable alternative to simple compartmental models suffering from detrimental effects of the well-mixed assumption.
Title: Impact of the topology of metapopulations on the resurgence of epidemics rendered by a new multiscale hybrid modeling approach
Example Output:
False