Some context: Henry Gustav Molaison (February 26, 1926 - December 2, 2008), known widely as H.M., was an American memory disorder patient who had a bilateral medial temporal lobectomy to surgically resect the anterior two thirds of his hippocampi, parahippocampal cortices, entorhinal cortices, piriform cortices, and amygdalae in an attempt to cure his epilepsy. Although the surgery was partially successful in controlling his epilepsy, a severe side effect was that he became unable to form new memories. H.M. was widely studied from late 1957 until his death in 2008. His case played an important role in the development of theories that explain the link between brain function and memory, and in the development of cognitive neuropsychology, a branch of psychology that aims to understand how the structure and function of the brain relates to specific psychological processes.
The study of Molaison revolutionized the understanding of the organization of human memory. It has provided broad evidence for the rejection of old theories and the formation of new theories on human memory, in particular about its processes and the underlying neural structures (cf. Kolb & Whishaw, 1996). In the following, some of the major insights are outlined. Molaison's brain was the subject of an anatomical study funded by the Dana Foundation and the National Science Foundation. The aim of the project, headed by Jacopo Annese, of The Brain Observatory at UC San Diego, was to provide a complete microscopic survey of the entire brain to reveal the neurological basis of Molaison's historical memory impairment at cellular resolution. On December 4, 2009, Annese's group acquired 2401 brain slices, with only two damaged slices and 16 potentially problematic slices. The digital 3D reconstruction of his brain was finished at the beginning of 2014. The results of the study were published in Nature Communications for January 2014. The researchers found, to their surprise, that half of H.M.'s hippocampus had survived the 1953 surgery, which has deep implications on past and future interpretations of H.M.'s neurobehavioral profile and of the previous literature describing H.M. as a 'pure' hippocampus lesion patient. Additionally, a previously unexpected discrete lesion was discovered in the prefrontal cortex. These findings suggest revisiting raw data from behavioral testing. A three-dimensional virtual model of the brain allowed the dynamics of the surgery to be reconstructed; it was found that the brain damage above the left orbit could have been created by Dr. Scoville when he lifted the frontal lobe to reach into the medial temporal lobes. The article also describes the general neuropathological state of the brain via multiple imaging modalities. As H.M. was 82 when he died, his brain had aged considerably. Several pathological features were discovered, some severe, which had contributed to his cognitive decline. The digital atlas of HM's brain was made publicly available on the Internet free of charge; its "permanence on the web relies on contributions from users".
Did Henry Molaison make any important contributions to science?
A: The study of Molaison revolutionized the understanding of the organization of human memory. It has provided broad evidence for the rejection of old theories
Some context: Crowded House are a rock band formed in Melbourne, Australia, in 1985. The founding members were New Zealander Neil Finn (vocalist, guitarist, primary songwriter) and Australians Paul Hester (drums) and Nick Seymour (bass). Later band members included Neil Finn's brother, Tim Finn, and Americans Mark Hart and Matt Sherrod. Originally active from 1985 to 1996, the band had consistent commercial and critical success in Australia and New Zealand and international chart success in two phases, beginning with their self-titled debut album, which reached number twelve on the US Album Chart in 1987 and provided the Top Ten hits
In 2006 Neil Finn asked Nick Seymour to play bass on his third solo album. Seymour agreed and the two joined up with producer and multi-instrumentalist Ethan Johns to begin recording. As the recording sessions progressed it was decided that the album would be issued under the Crowded House band name, rather than as a Neil Finn solo album. In January 2007, the group publicly announced their reformation and on 23 February, after 20 days of auditions, former Beck drummer Matt Sherrod joined Finn, Seymour and Mark Hart to complete the new line up. As Sherrod and Hart had not participated in the initial sessions, four new tracks were recorded with producer Steve Lillywhite including the album's first single "Don't Stop Now". On 17 March 2007 the band played a live show at their rehearsal studio in front of around fifty fans, friends and family. The performance was streamed live as a webcast. The two-and-a-half-hour set included some new tracks, including "Silent House" co-written by Finn with the Dixie Chicks. A concert onboard The Thekla, moored in Bristol, followed on 19 March. Crowded House played at the Marquee Theatre in Tempe, Arizona on 26 April as a warm-up for their appearance at the Coachella Festival on 29 April in Indio, California. They also played at the Australian Live Earth concert in Sydney on 7 July. The next day, Finn and Seymour were interviewed on Rove Live and the band, with Hart and Sherrod, performed "Don't Stop Now" to promote the new album, which was titled Time on Earth. The single was a minor hit in Australia and the UK. The album was released worldwide in June and July. It topped the album chart in New Zealand and made number 2 in Australia and number 3 in the UK. On 6 December 2008 Crowded House played the Homebake festival in Sydney, with warm up gigs at small venues in Hobart, Melbourne and Sydney. For these shows the band were augmented by multi-instrumentalist Don McGlashan and Neil's younger son, Elroy Finn, on guitar. On 14 March 2009 the band joined Neil's older son, Liam Finn, on stage for three songs at the Sound Relief concert in Melbourne.
How did that work out?
A:
For these shows the band were augmented by multi-instrumentalist Don McGlashan and Neil's younger son, Elroy Finn, on guitar.