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Charles Darwin's grandfather Erasmus Darwin outlined a hypothesis of transmutation of species in the 1790s, and Jean-Baptiste Lamarck published a more developed theory in 1809. Both envisaged that spontaneous generation produced simple forms of life that progressively developed greater complexity, adapting to the environment by inheriting changes in adults caused by use or disuse. This process was later called Lamarckism. Lamarck thought there was an inherent progressive tendency driving organisms continuously towards greater complexity, in parallel but separate lineages with no extinction. Geoffroy contended that embryonic development recapitulated transformations of organisms in past eras when the environment acted on embryos, and that animal structures were determined by a constant plan as demonstrated by homologies. Georges Cuvier strongly disputed such ideas, holding that unrelated, fixed species showed similarities that reflected a design for functional needs. His palontological work in the 1790s had established the reality of extinction, which he explained by local catastrophes, followed by repopulation of the affected areas by other species.

Whose paleontology work in the 1790s established the reality of extinction?
Answer: Georges Cuvier
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The Luftwaffe's poor intelligence meant that their aircraft were not always able to locate their targets, and thus attacks on factories and airfields failed to achieve the desired results. British fighter aircraft production continued at a rate surpassing Germany's by 2 to 1. The British produced 10,000 aircraft in 1940, in comparison to Germany's 8,000. The replacement of pilots and aircrew was more difficult. Both the RAF and Luftwaffe struggled to replace manpower losses, though the Germans had larger reserves of trained aircrew. The circumstances affected the Germans more than the British. Operating over home territory, British flyers could fly again if they survived being shot down. German crews, even if they survived, faced capture. Moreover, bombers had four to five crewmen on board, representing a greater loss of manpower. On 7 September, the Germans shifted away from the destruction of the RAF's supporting structures. German intelligence suggested Fighter Command was weakening, and an attack on London would force it into a final battle of annihilation while compelling the British Government to surrender.

Britain's fabrication of fighter planes out paced Germany by what margin?
Answer: 2 to 1
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The foundation has donated billions of dollars to help sufferers of AIDS, tuberculosis and malaria, protecting millions of children from death at the hands of preventable diseases. However, a 2007 investigation by The Los Angeles Times claimed there are three major unintended consequences with the foundation's allocation of aid. First, sub-Saharan Africa already suffered from a shortage of primary doctors before the arrival of the Gates Foundation, but "by pouring most contributions into the fight against such high-profile killers as AIDS, Gates grantees have increased the demand for specially trained, higher-paid clinicians, diverting staff from basic care" in sub-Saharan Africa. This "brain drain" adds to the existing doctor shortage and pulls away additional trained staff from children and those suffering from other common killers. Second, "the focus on a few diseases has shortchanged basic needs such as nutrition and transportation". Third, "Gates-funded vaccination programs have instructed caregivers to ignore even discourage patients from discussing ailments that the vaccinations cannot prevent".

What has the focus on a few diseases caused
Answer:
"the focus on a few diseases has shortchanged basic needs such as nutrition and transportation