Given a scientific passage and an answer, generate a question for the given answer.

[EX Q]: Passage: Saliva Saliva is essentially (95.5 percent) water. The remaining 4.5 percent is a complex mixture of ions, glycoproteins, enzymes, growth factors, and waste products. Perhaps the most important ingredient in salvia from the perspective of digestion is the enzyme salivary amylase, which initiates the breakdown of carbohydrates. Food does not spend enough time in the mouth to allow all the carbohydrates to break down, but salivary amylase continues acting until it is inactivated by stomach acids. Bicarbonate and phosphate ions function as chemical buffers, maintaining saliva at a pH between 6.35 and 6.85. Salivary mucus helps lubricate food, facilitating movement in the mouth, bolus formation, and swallowing. Saliva contains immunoglobulin A, which prevents microbes from penetrating the epithelium, and lysozyme, which makes saliva antimicrobial. Saliva also contains epidermal growth factor, which might have given rise to the adage "a mother's kiss can heal a wound. " Each of the major salivary glands secretes a unique formulation of saliva according to its cellular makeup. For example, the parotid glands secrete a watery solution that contains salivary amylase. The submandibular glands have cells similar to those of the parotid glands, as well as mucus-secreting cells. Therefore, saliva secreted by the submandibular glands also contains amylase but in a liquid thickened with mucus. The sublingual glands contain mostly mucous cells, and they secrete the thickest saliva with the least amount of salivary amylase. Answer: enzyme
[EX A]: Arguably the most important ingredient in saliva for digestion is a type of what, which initiates the breakdown of carbohydrates?

[EX Q]: Passage: The last major ice age took place in the Pleistocene. This epoch lasted from 2 million to 14,000 years ago. Earth's temperature was only 5 C (9 F) cooler than it is today. But glaciers covered much of the Northern Hemisphere. In Figure below , you can see how far south they went. Clearly, a small change in temperature can have a big impact on the planet. Humans lived during this ice age. Answer: pleistocene
[EX A]: The last major ice age took place in which era?

[EX Q]: Passage: Chromosomal disorders also occur when part of a chromosome becomes damaged. For example, if a tiny portion of chromosome 5 is missing, the individual will have cri du chat (cat's cry) syndrome. These individuals have misshapen facial features, and the infant's cry resembles a cat's cry. Answer: chromosome 5
[EX A]:
Which chromosome is associated with cri du chat syndrome?