In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Q: Paragraph: The eight different types of ubiquitin (Ub) chains that can be formed play important roles in diverse cellular processes. Linkageselective recognition of Ub chains by Ub-binding domain (UBD)containing proteins is central to coupling different Ub signals to specific cellular responses. The motif interacting with ubiquitin (MIU) is a small UBD that has been characterized for its binding to monoUb. The recently discovered deubiquitinase MINDY-1/FAM63A contains a tandem MIU repeat (tMIU) that is highly selective at binding to K48-linked polyUb. We here identify that this linkageselective binding is mediated by a single MIU motif (MIU2) in MINDY-1. The crystal structure of MIU2 in complex with K48-linked polyubiquitin chains reveals that MIU2 on its own binds to all three Ub moieties in an open conformation that can only be accommodated by K48-linked triUb. The weak Ub binder MIU1 increases overall affinity of the tMIU for polyUb chains without affecting its linkage selectivity. Our analyses reveal new concepts for linkage selectivity and polyUb recognition by UBDs.
Title: A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains

A: False
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Q: Paragraph: We apply the information categorization method and succeed to classify the financial markets. We investigate the similarity among US and Chinese stock indices for the Asian currency crisis and the global financial crisis. The phylogenetic trees of different stock indices are presented and provide obvious phenomenon. The paper mainly applies the information categorization method to analyze the financial time series. The method is used to examine the similarity of different sequences by calculating the distances between them. We apply this method to quantify the similarity of different stock markets. And we report the results of similarity in US and Chinese stock markets in periods 1991-1998 (before the Asian currency crisis), 1999-2006 (after the Asian currency crisis and before the global financial crisis), and 2007-2013 (during and after global financial crisis) by using this method. The results show the difference of similarity between different stock markets in different time periods and the similarity of the two stock markets become larger after these two crises. Also we acquire the results of similarity of 10 stock indices in three areas; it means the method can distinguish different areas' markets from the phylogenetic trees. The results show that we can get satisfactory information from financial markets by this method. The information categorization method can not only be used in physiologic time series, but also in financial time series.
Title: Physica A Financial time series analysis based on information categorization method

A: True
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Q: Paragraph: High-frequency oscillatory ventilation (HFOV) is characterized by the rapid delivery of small tidal volumes (VTs) of gas and the application of high mean airway pressures (mPaws). These characteristics make HFOV conceptually attractive as an ideal lung-protective ventilatory mode for the management of ARDS, as the high mPaws prevent cyclical derecruitment of the lung and the small VTs limit alveolar overdistension. In this review, we will summarize the literature describing the use of HFOV in adult patients with ARDS. In addition, we will discuss recent experimental studies of HFOV that have advanced our understanding of its mechanical properties. We identified 2 randomized controlled trials (RCTs) and 12 case series evaluating HFOV in adults with ARDS. In these studies, HFOV appears to be safe and consistently improves oxygenation when used as a rescue mode of ventilation in patients with severe ARDS. The two RCTs comparing HFOV to conventional ventilation revealed encouraging results but failed to show a mortality benefit of HFOV over conventional ventilation. Further research is needed to identify optimal patient selection, technique, the actual VT delivered, and the role of combining HFOV with other interventions, such as recruitment maneuvers, prone positioning, and nitric oxide. (CHEST 2007; 131:1907-1916 Abbreviations: ALI acute lung injury; APACHE acute physiology and chronic health evaluation; CMV conventional mechanical ventilation; CO cardiac output; CVP central venous pressure; Fio 2 fraction of inspired oxygen; ETT endotracheal tube; HFJV high-frequency jet ventilation; HFOV high-frequency oscillatory ventilation; HFV high-frequency ventilation; IL interleukin; iNO inhaled nitric oxide; mPaw mean airway pressure; OI oxygenation index; P pressure amplitude; PAOP pulmonary artery occlusion pressure; PCV pressure-controlled ventilation; PEEP positive end-expiratory pressure; RCT randomized controlled trial; RM recruitment maneuver; VILI ventilator-induced lung injury; Vt tidal volume
Title: High-Frequency Oscillatory Ventilation for Adult Patients With ARDS*

A:
True
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