Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Example Input: Paragraph: Pfizer shares were up nearly 4 percent on positive findings for the oral treatment, called palbociclib, one of the company's most important experimental drugs that some analysts believe could eventually claim annual sales of more than $5 billion, if approved. The trial tested the pill in post-menopausal patients with locally advanced or newly diagnosed breast cancer that had spread to other parts of the body. "We are delighted with the final data," Pfizer said in a release, adding the company will discuss the successful data on progression-free survival with the U.S. Food and Drug Administration "to determine next steps" for palbociclib. A secondary goal of the study is to determine whether palbociclib can prolong overall survival. But Pfizer spokeswoman Sally Beatty said the company does not yet have such data, because it takes longer periods to follow patients and gauge survival trends. Although Pfizer is conducting two larger late-stage trials of palbociclib, ISI Group analyst Mark Schoenebaum noted the company has previously said it might discuss with the FDA the potential to seek approval of the medicine based upon mid-stage trial data, if the data warranted. Palbociclib, which blocks enzymes known as cyclin-dependent kinases (CDKs) 4 and 6, was taken in combination with a standard treatment called letrozole among women who were estrogen receptor positive - meaning tumors grow in response to estrogen - and HER2-negative, meaning that the HER2 protein is not causing the cancer. Such patients make up about 60 percent of advanced breast cancer cases. Letrozole is the chemical name of Femara, a Novartis AG drug that belongs to a class of treatments called aromatase inhibitors that block production of estrogen. Pfizer on Monday did not present detailed data from the trial results, saying they would be presented at a scientific meeting in San Diego in April. The success of the trial, called Paloma-1, follows highly favorable interim data that Pfizer unveiled in December 2012. At that point in the study, those taking both palbociclib and letrozole went an average of 26.1 months before tumors worsened. That compared with 7.5 months for those taking letrozole, but not palbociclib. The 18.6-month difference was considered statistically significant. Side effects from palbociclib were similar to those previously reported, Pfizer said on Monday. The earlier interim results had shown that patients taking the drug combination experienced anemia, fatigue and neutropenia - a decline in white blood cells called neutrophils that can put patients at higher risk of infection. Palbociclib was designated a "breakthrough" drug by the FDA last April based on initial data from the trial. The FDA grants "breakthrough" status to drugs that may offer substantial improvement over existing treatments for serious or life-threatening diseases. The status helps to speed up the approval process. Pfizer has started two late-stage trials of the drug - Paloma-2 and Paloma-3 - in patients with advanced breast cancer. Paloma-2 will test the same drug combination, palbociclib and letrozole, as an initial treatment for breast cancer. Paloma-3 will evaluate palbociclib in combination with another hormone therapy, fulvestrant, in women whose cancer has progressed after hormonal therapy. The drug, sold under the brand name Faslodex by AstraZeneca Plc, is called an estrogen receptor antagonist. Companies trying to develop treatments similar to palbociclib include Novartis and Eli Lilly & Co. Breast cancer killed more than 508,000 women worldwide in 2011, according to the World Health Organization. Pfizer shares were up 3.7 percent at $31.53 on Monday morning on the New York Stock Exchange. Claim: Pfizer breast cancer drug succeeds in mid-stage trial.
Example Output: Pfizer Inc's experimental breast cancer drug significantly delayed progression of symptoms in a mid-stage trial, meeting the study's primary goal and keeping Pfizer in the forefront of a race for a new standard of care for the disease.

Example Input: Paragraph: As the new coronavirus spreads from China, travel guidelines being issued by governments across the world all express notes of growing caution. But they contain subtle differences on where to avoid, how to behave and what to do after a trip. With few exceptions, the prevailing advice of national authorities is to avoid Hubei province - epicenter of an outbreak that has now infected 80,000 people worldwide - and to reduce Chinese travel to the bare minimum. Once inside China, Swiss travelers for example are urged by their government to avoid large gatherings and "cough or sneeze into a tissue, or use the crook of your arm". France tells its nationals not to eat raw meat or visit animal markets. The Spanish Foreign Ministry also urges against contact with animals in China and suggests making sure that you stay at least one meter away from the next person. For travelers to Italy - the country most badly hit by the virus in Europe - the Dutch government recommends that its citizens avoid areas already locked down by local authorities and only travel to parts of the wider Lombardy region around the closed-off towns if necessary. The Finnish Foreign Ministry advice on Italy is simply to "take special care". Differences also emerge in the advice to travelers on their return from an affected area. Germany's main authority for infectious diseases tells those returning with symptoms from outbreak regions in Italy to see a doctor and call prior to their visit. But France asks such people not to visit the doctor but to call emergency services. Britain urges its nationals to "self-isolate" at home if they have been to the areas quarantined by Italy whether or not they have symptoms. The Danish Health Authority currently stipulates no routine quarantine or isolation of people who have traveled to China or other places hit by the outbreak. Countries outside Europe take different stances. Turkey advises against all but essential travel to China but has not yet issued travel advice on Italy. Nigeria has a voluntary two-week self-quarantine in place for all passengers arriving from China or any country with "a major outbreak". Guidance for returning air passengers says "try to avoid" going out but wear a mask if you do. Claim: Coronavirus travel: national advice not all of a piece.
Example Output: Should travelers avoid parts of the world near coronavirus hotspots? Or go - but then tread carefully? The official advice they receive may depend on whether they live in Amsterdam, Helsinki, Madrid or Lagos.

Example Input: Paragraph: On 30 April 2019, the Facebook page "Historical Pictures" renewed interest in an old news story involving the movie Titanic, seafood chowder, and the drug PCP (Phencyclidine, or angel dust): The Facebook page reads: "On the last night of filming Titanic, someone laced the cast and crew's food with PCP. 80 cast and crew members, including James Cameron and Bill Paxton, started hallucinating and had to be hospitalized." This Facebook post recounts a genuine news story from the set ofTitanic. However, some of the details are misleading or inaccurate. For instance, this incident occurred during the final day of shooting at one specific location but not the final day overall for the film: The location was the Halifax area on the Akademik Msislav Keldysh research vessel that Cameron used to film the underwater sequences, a year earlier. Fifty crew members made the trip to Nova Scotia for what was supposed to be a pit stop to the main event. However, on 9 August 1996, three weeks into filming, all hell broke loose when several people fell violently ill after a dinner break. More importantly, the included image in this Facebook post is misleading, as neither of the movie's stars, Leonardo DiCaprio or Kate Winslet, were on set at the time of the incident. On 26 August 1996, the Canadian press reported that nearly 80 people were taken to the hospital from the set of Titanicfor what was initially thought to be food poisoning. However, the Halifax regional police investigated the incident and found that someone had laced the seafood chowder with PCP: Thu, Aug 29, 1996 30 Star-Phoenix (Saskatoon, Saskatchewan, Canada) Newspapers.com Though the movie's lead stars were not on set during this incident, other big names attached to the film, such as actor Bill Paxton and director James Cameron, were on set and did eat the PCP-laced chowder. Paxton was quoted byEntertainment Weekly in 1996 saying that he typically didn't eat the catering on the set but on that night, for whatever reason, he decided to join Cameron for a bowl of the chowder: Exactly who spiked the chowder remains a mystery and the source of an ongoing criminal investigation but for actor Bill Paxton (Twister), who plays a modern-day treasure hunter, it was truly a night to remember. After planning to eat Italian food in his trailer, Paxton opted instead to join Cameron for a bowl of lobster chowder. Within 15 minutes after eating, he recalls, "the crew was all milling about. Some people were laughing, some people were crying, some people were throwing up." Assuming that bad shellfish had caused the problem, Paxton jumped in a van headed for Dartmouth General Hospital. "One minute I felt okay," he says, "the next minute I felt so goddamn anxious I wanted to breathe in a paper bag. Cameron was feeling the same way." Paxton also recounted the experience during an interview with Larry King: Several other people who were on set that day have given their own versions of this story. Marilyn McAvoy, who was a standby painter on the set, spoke with Vice in May 2017: Vice: Hey Marilyn, so tell me, what was that chowder like? Marilyn McAvoy: The chowder was unbelievable. People were going back for second bowls. I really thought about going back because it was so good. And I think that was part of the problem: People ate a lot more than usual because it was so delicious. What else do you remember about that night? There was no indication that there was anything strange happening until the meal. By the time we got back from eating, after about 30 minutes, that's when I started noticing something was wrong. Everyone seemed confused. Everyone was having trouble getting their work done. [] How did the rest of the crew react? While I was trying to figure out what was going on, everyone else seemed to be going outside. They were all gathering outside of the giant doors of the building we were working in. I also heard later on that as soon as James Cameron realized something had been put in the chowder, he ran up to his room and forced himself to throw up. This incident is also mentioned in abiography of DiCaprio. In it, actor Lewis Abernathy was quoted describing how Cameron allegedly looked after eating the drug-laced chowder: Actor Lewis Abernathy, who played a cynical sidekick to Bill Paxton's relic hunter, recalled: "There were people just rolling around, completely out of it. Some of them said they were seeing streaks and psychedelics." "I thought it was food poisoning," he continued (luckily he had eaten in his hotel that night). "Really bad seafood can make you hallucinate and this caterer was big on clams. Jim was being loaded into the back of this van I was just shocked at the way he looked. One eye was completely red, like the Terminator eye a pupil, no iris, beet red. The other eye looked like he'd been sniffing glue since he was four." Cameron confirmed that he had eaten the chowder but said that he avoided a trip to the hospital by forcing himself to throw up the contaminated food. While police confirmed that numerous people on the movie set were sickened after eating PCP-laced seafood chowder, investigators never found out who was responsible. Some suspected that the culprit was a disgruntled chef, while others believed that a crew member was attempting to get revenge on Cameron, who has a reputation for being a tyrannical director. As far as we can tell, the person who put drugs in the chowder was never identified and no charges were ever filed over the incident. In 1998, the Calgary Herald published an article entitled "Titanic Mystery: Who Spiked the Chowder?" In it, both Paxton and Cameron expressed their anger (as well as confusion) over the incident, saying that whoever laced the chowder put everyone on set, including elderly people and children, in danger: Thu, Jan 15, 1998 63 Calgary Herald (Calgary, Alberta, Canada) Newspapers.com Some disagreement exists over the exact number of people who were sickened or the type of chowder (lobster, clam, or seafood?) that was laced with PCP. However, it is undoubtedly true that dozens of people unknowingly took angel dust on the set of Titanic after an unidentified person spiked the food with it. Claim: "Dozens of people on the set of the film ""Titanic"" were sickened after eating seafood chowder that had been spiked with the drug PCP on the final day of shooting."
Example Output:
What's true: Dozens of people on the set of "Titanic," including actor Bill Paxton and director James Cameron, were sickened after someone laced the seafood chowder with PCP. What's false: The movie's stars, Leonardo DiCaprio and Kate Winslet, were not on set at the time, and the incident did not occur on the final day of shooting.