instruction:
Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
question:
Abstract: We report a rare case of supra- and infratentorial arteriovenous malformations (AVMs), which were separate and consisted of aneurysmal dilations with two or three afferent arteries and efferent veins. Surgical resections were performed without the occurrence of additional neurological deficits. We discuss the treatment of multiple AVMs and stress that size and the structures involved are more important factors in the prognosis than the multiplicity of the lesions.
Which is the apt title for the abstract? option1: Supra- and infratentorial arteriovenous malformations with an aneurysmal dilatation: a case report. option2: Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis.
answer:
Supra- and infratentorial arteriovenous malformations with an aneurysmal dilatation: a case report.

question:
Abstract: The System 7 pump/actuator/engine combination has demonstrated biologic compatibility and physiologic effectiveness and responsiveness in five TVAS in vivo studies. The recent 75-day implant supports the feasibility of extended reliability of the system components. Postoperative system maintenance was necessary only because of the nonhermetic design of System 7. However, the ability to pump 11 l/min at 120 beats/min, synchronize at beat rates of 144 beats/min, and pump against mean arterial pressures of more than 150 mmHg while maintaining hematologic and biochemical values within physiologic range sets a very optimistic stage for System 8 hardware. A System 8 concept is shown in Figure 14. The System 8 hardware will include a thermal salt package capable of providing completely untethered circulatory support for a nominal 8-h period. Recharge will be accomplished with a transcutaneous transformer in 1 h. Thermal management problems become minimal, with an average energy input of 15.8 W (peak of 24.9 W). The human preclinical testing of System 8 will start in 1988.
Which is the apt title for the abstract? option1: In vivo evaluation of a permanently implantable thermal ventricular assist system. option2: Coexistent systemic lupus erythematosus and urate deposition [letter]
answer:
In vivo evaluation of a permanently implantable thermal ventricular assist system.

question:
Abstract: The contractile action of cholecystokinin (CCK) on smooth muscle of the gut is either direct (gallbladder and gastric fundus) or both direct and neurally mediated (small intestine). These regional differences were used to characterize pharmacologically CCK receptors on smooth muscle cells and neurons of the gastric fundus, gallbladder, and ileum of the guinea pig. In circular and longitudinal ileal smooth muscle, tetrodotoxin was used to separate direct from neurally mediated contractile effects. Cholecystokinin receptors on smooth muscle cells were found in all locations. The muscle cells displayed a decreasing order of sensitivity to the C-terminal octapeptide of cholecystokinin as expressed in the median doses, and to the selective cholecystokinin antagonist, proglumide, as expressed in the inhibitory dissociation constants. The median doses of the octapeptide of cholecystokinin ranged from 5.5 nM in gallbladder muscle to 185 nM in circular ileal muscle; the corresponding inhibitory dissociation constants of proglumide ranged from 180 to 437 microM [corrected]. Cholecystokinin receptors on cholinergic neurons were confined to circular and longitudinal ileal muscle; the neurons were 80-300 times more sensitive to the octapeptide of cholecystokinin (D50's 0.5 and 2.3 nM) than the corresponding muscle cells, and 19-21 times more sensitive to proglumide (inhibitory dissociation constants, 20 microM [corrected]). The results provide clear evidence of cellular heterogeneity of cholecystokinin receptors (i.e., difference in sensitivity between muscle cells and neurons from the same location) as well as regional heterogeneity (i.e., difference in sensitivity between muscle cells from various locations).
Which is the apt title for the abstract? option1: Regional and cellular heterogeneity of cholecystokinin receptors mediating muscle contraction in the gut [published erratum appears in Gastroenterology 1987 Jun;92(6):2055] option2: Ex vivo renal artery reconstructions: indications and techniques.
answer:
Regional and cellular heterogeneity of cholecystokinin receptors mediating muscle contraction in the gut [published erratum appears in Gastroenterology 1987 Jun;92(6):2055]