TASK DEFINITION: Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
PROBLEM: Paragraph: We'll give the story a "N/A" in this category since it makes clear early on that this research is in the earliest of stages, done in an animal model, and says clearly that clinical trials are a future hope. This is way too early to consider costs which, we assume, would be substantial. The story says the stem cell intervention extended the rodents' lives "by 10-15% compared to untreated animals." At another point, it said, "the mice lived longer than controls, typically several months more, an increase of about 15%." The story makes no mention of the potential harms that might arise from this approach. Since this has never been tested in humans, we have no idea what they risks are. The story needed to point this out. Theoretically, the stem cells would have to be delivered into human brains via injections, which would make the intervention incredibly risky and possibly a non-starter. In the original paper, the stem cells were injected into the hypothalamus of the mice using viruses as "vectors." The researchers used lentiviruses, which are used often as vectors for research, but can be deadly in humans. Some discussion of this hurdle also was warranted. The story does a good job at explaining various aspects of the research and depicting the stages through which the research team drew its conclusions. It also is up front about this being animal research, so far untried in humans at even the earliest stages of clinical trials. Of note, the original paper mentions that this study was conducted in very few mice (total of about 20) and only in male mice. That detail would have been useful to include. One thing we wanted to point out that was problematic: The story said "if a similar extension was achieved in humans, a person with a life expectancy of 80 years could live to 92." We have no idea how this may impact humans; the evidence doesn't support that kind of speculation. The story doesn't appear to commit disease mongering, though it could have pointed out that aging in and of itself is not a disease. The story does quote one source unaffiliated with the research and we didn't detect any conflicts of interest. (The paper itself notes that the authors of the study have no conflicts of interests.) The story is all about basic research that suggests an approach that one day might slow, or possibly reverse, the aging process. There are no real alternatives available now to affect the aging process beyond lifestyle choices that might be healthier and appropriate treatments for illnesses that might otherwise shorten lifespans. It's clear from the story that this research is preliminary. The story clearly says, "The next step is to create human neural stem cells in the lab for testing." It also states that, "Researchers at Albert Einstein College of Medicine in New York hope to launch clinical trials of the procedure soon, but must first produce supplies of human neural stem cells in the lab which can be implanted into volunteers." The story heralds this research as a "tour de force" and a "breakthrough." Yet is it accurate in a news story to call anything done in animals a "breakthrough?" That word implies relevance to humans, and this is far from established in a mouse study. Studies in mice are essential but many of them fail to show similar evidence in humans. Likewise, stem cell research is often seen as a magic bullet for some conditions but there have been few cases where the preliminary hope/hype has born out. The story does not appear to rely on a news release. Claim: Stem cell brain implants could 'slow ageing and extend life', study shows

SOLUTION: This story describes some interesting but very early research into the mechanisms of aging and how they might be altered. The story made it clear that this was mouse-level research and has several hurdles to go before it's ever tested in people. One weak point for the story was how the story assumed there might be benefits in people yet overlooked the potential risks. Considering this intervention involves inserting stem cells into the brain via the assistance of a viral strain known to be harmful to humans, it's logical to assume there could be some safety concerns. It also overplayed the novelty here by quoting an expert who called it a "tour de force" and a "breakthrough." The desire to somehow combat aging seems inherent in humans. If there is a fairly straightforward "switch" that can control the aging process and this story suggests so then this would be a major advance. Yet we are looking at decades before this becomes a rigorous Phase III human trial, let alone a potential intervention in humans. The bottom line is: We are talking about approximately 20 male mice.

PROBLEM: Paragraph: The public-private partnership includes the World Health Organization, UNICEF, the Bill & Melinda Gates Foundation and the World Bank, among others. The funding announcement was made after a meeting of GAVI's board. GAVI said the investment, which it called an estimate, will be provided between now and 2025. Since the current outbreak in eastern Congo was identified last August, health officials have immunized more than 255,000 people with a recently licensed vaccine made by Merck. To date there have been nearly 3,200 confirmed Ebola cases, including more than 2,200 deaths, in what has become the second deadliest Ebola outbreak in history. Dr. Ngozi Okonjo-Iweala, chair of Gavi's board, called the creation of the Ebola vaccine stockpile a "historic milestone in humanity's fight against this horrific disease." GAVI said "a coordinating mechanism" to decide how and when vaccines will be used will be established with partner organizations. There are similar stockpiles for vaccines against yellow fever, meningitis and cholera. Those limited shots are doled out to developing countries by WHO, UNICEF, the Red Cross and Doctors Without Borders after receiving technical advice from others. The Ebola vaccine stockpile will be available to all countries, but only developing countries will be able to get vaccines for free in addition to support for the logistical costs of mounting vaccination campaigns. Jason Nickerson, a humanitarian affairs adviser at Doctors Without Borders, said the new stockpile would change how officials respond to future Ebola outbreaks. "Knowing how many doses of the vaccine exist in the world, and then being able to get a supply of them to high-risk countries in a very quick way, gives us another tool to respond to these outbreaks," he said. Earlier this year, the medical charity publicly called for an independent committee to oversee Ebola vaccination efforts in Congo, saying WHO sometimes used arbitrary criteria to determine who would get immunized. It said the fact that Ebola was continuing to spread despite the large number of people vaccinated was a damning assessment of the response. Containing this outbreak has been complicated by violence and misunderstandings in a part of Congo that had never reported an Ebola case before. Last week, response activities were suspended after attacks killed four Ebola responders, including a member of a vaccination team. Multiple rebel groups operate in eastern Congo and the region has been described as a war zone. WHO has warned continued attacks on health workers and Ebola clinics could undermine attempts to curb Ebola and prompt a resurgence of the disease. Claim: Vaccine group announces creation of Ebola vaccine stockpile.

SOLUTION: The vaccine alliance GAVI announced Thursday it would invest $178 million to create a global stockpile of about 500,000 Ebola vaccines, a decision that health officials say could help prevent future outbreaks from spiraling out of control.

PROBLEM: Paragraph: While the cause remains unclear, officials said Friday that many reports involve e-cigarette products that contain THC, the mind-altering substance in marijuana. Officials from the Centers for Disease Control and Prevention said they are looking at 215 possible cases across 25 states. All the cases involve teens or adults who have used e-cigarettes or other vaping devices. Symptoms of the disease include coughing, shortness of breath, chest pain, fatigue, nausea and vomiting. The CDC and Food and Drug Administration warned the public not to buy vaping products off the street. And officials recommended people concerned about the health risks "consider refraining from using e-cigarette products." Health and Human Services Secretary Alex Azar said in a statement the government is "using every tool we have to get to the bottom of this deeply concerning outbreak." E-cigarettes generally heat a flavored nicotine solution into an inhalable aerosol. The products have been used in the U.S. for more than a decade and are generally considered safer than traditional cigarettes because they don't create all the cancer-causing byproducts of burning tobacco. But some vaping products have been found to contain other potentially harmful substances, including flavoring chemicals and oils used for vaping marijuana, experts say. The mysterious illness underscores the complicated nature of the vaping market, which includes both government-regulated nicotine products and THC-based vape pens, which are considered illegal under federal law. Eleven states and the District of Columbia allow marijuana for recreational use. THC-based products in these regulated markets are generally inspected for quality and safety, but there is a largely unregulated gray market. On Thursday, top health officials in the Trump administration reiterated warnings against marijuana use by adolescents and pregnant women, emphasizing the increasing potency of the drug. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education. The AP is solely responsible for all content. Claim: More vaping illnesses reported, many involving marijuana.

SOLUTION:
Health officials are recommending people who vape consider avoiding e-cigarettes while they investigate more cases of a breathing ailment linked to the devices.