Detailed Instructions: Given a scientific passage and an answer, generate a question for the given answer.
See one example below:
Problem: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Explanation: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

Problem: Passage: Elements are pure substances that make up all matter, so each one is given a unique name. The names of elements are also represented by unique one-, two-, or three- letter symbols. Answer: all matter
Solution:
Elements are pure substances that make up what?