Definition: In this task you will be given a text passage from a trivia quiz. You should choose the category this question belongs to from these categories: History, Science, Social Science, Fine Arts, Literature. You can only choose one category, so if in doubt, please choose the closest match.
Input: may contribute to the cerebral type of this disease as a result of up-regulation of ICAM-1. Deficiency of glucose-6-phosphate dehydrogenase increases resistance to this disease, as do certain thalassemias. It causes the membranes of certain cells to become porous seconds before making them burst. Humans who are Duffy blood group negative are protected from one agent causing this disease that lacks redundancy in invasion pathways, P. vivax. Affected cells become deformed easily, leading to an outward diffusion of potassium that makes those cells less hospitable for P. falciparum in humans who are heterozygous for hemoglobin S. That heterozygosity, which also allows the spleen to preferentially destroy infected red blood cells, is sickle cell anemia. For 10 points, name this disease commonly treated with quinine which is caused by Plasmodium and transmitted by the Anopheles mosquito.
Output:
Science