Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).

Ex Input:
Abstract: Sixteen adult subjects with asthma in a clinical steady state were studied. On day 1, after baseline spirometry, they underwent four histamine inhalation tests with functional recovery between each test. The provocative concentration causing a 20% fall in FEV1 (PC20) was obtained after each test. On days 2, 3, and 4, after baseline spirometry, active and placebo ascorbic acid (2 gm) was administered orally, double-blind, according to a 4.3.1 two-treatment crossover study design. One hour later, spirometry was performed, and PC20 was reassessed. We found no significant changes in FEV1 and FVC after ascorbic acid as compared with placebo administration. There was no difference between PC20 on days 2, 3, and 4 and by standardizing for the four PC20 results obtained on day 1. We conclude that ascorbic acid has no acute bronchodilator effect and does not alter bronchial responsiveness to histamine in subjects with asthma.
Which is the apt title for the abstract? option1: Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. option2: AIDS drug test [news]

Ex Output:
Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma.

Ex Input:
Abstract: The IgG and IgM specific antibodies against a panel of 23 anaerobic gut bacteria were examined in Crohn's disease, ulcerative colitis, and healthy controls. Four of the organisms, Bifidobacterium bifidum, Coprococcus comes (ME46), Coprococcus comes (Sp4), and Eubacterium limosum gave abnormal antibody titres in Crohn's disease compared with those of controls. In Crohn's disease specific IgG antibodies to three of the organisms were low and the IgM antibodies were higher than those of controls. IgM antibodies were also raised in ulcerative colitis. Antigenic cross reactivity could be shown between some of these organisms. The possible clinical importance of these abnormal antibody responses to specific organisms is unexplained.
Which is the apt title for the abstract? option1: Antibody response to anaerobic coccoid rods in Crohn's disease. option2: Hypodiploid hemopoietic precursors in myelodysplastic syndromes [letter]

Ex Output:
Antibody response to anaerobic coccoid rods in Crohn's disease.

Ex Input:
Abstract: Endomyocardial biopsy is most frequently used to establish a definitive diagnosis of myocarditis, especially since this disorder has been treated with immunosuppressive therapy. Recent diagnostic criteria (the "Dallas Classification") are reviewed, and pitfalls and limitations are discussed.
Which is the apt title for the abstract? option1: Diagnosis of myocarditis by endomyocardial biopsy. option2: Obliteration of compressed frontal sinus [letter]

Ex Output:
Diagnosis of myocarditis by endomyocardial biopsy.