TASK DEFINITION: In this task, you are given a part of an article. Your task is to generate headline (title) for this text. Preferred headlines are under fifteen words.
PROBLEM: Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on pre-defined, hand-crafted radiomic feature sets that can limit their ability to characterize unique cancer traits. In this study, we introduce a novel discovery radiomics framework where we directly discover custom radiomic features from the wealth of available medical imaging data. In particular, we leverage novel StochasticNet radiomic sequencers for extracting custom radiomic features tailored for characterizing unique cancer tissue phenotype. Using StochasticNet radiomic sequencers discovered using a wealth of lung CT data, we perform binary classification on 42,340 lung lesions obtained from the CT scans of 93 patients in the LIDC-IDRI dataset. Preliminary results show significant improvement over previous state-of-the-art methods, indicating the potential of the proposed discovery radiomics framework for improving cancer screening and diagnosis.

SOLUTION: Discovery Radiomics via StochasticNet Sequencers for Cancer Detection

PROBLEM: Recently there has been significant activity in developing algorithms with provable guarantees for topic modeling. In standard topic models, a topic (such as sports, business, or politics) is viewed as a probability distribution ai over words, and a document is generated by first selecting a mixture w over topics, and then generating words i.i.d. from the associated mixture Aw. Given a large collection of such documents, the goal is to recover the topic vectors and then to correctly classify new documents according to their topic mixture. In this work we consider a broad generalization of this framework in which words are no longer assumed to be drawn i.i.d. and instead a topic is a complex distribution over sequences of paragraphs. Since one could not hope to even represent such a distribution in general (even if paragraphs are given using some natural feature representation), we aim instead to directly learn a document classifier. That is, we aim to learn a predictor that given a new document, accurately predicts its topic mixture, without learning the distributions explicitly. We present several natural conditions under which one can do this efficiently and discuss issues such as noise tolerance and sample complexity in this model. More generally, our model can be viewed as a generalization of the multi-view or co-training setting in machine learning. Supported in part by National Science Foundation grants CCF-1525971 and CCF-1535967. Supported in part by National Science Foundation grant CCF-1525971 and by a Microsoft Research Graduate Fellowship and an IBM Ph.D Fellowship. ar X iv :1 61 1. 01 25 9v 1 [ cs .L G ] 4 N ov 2 01 6

SOLUTION: Generalized Topic Modeling

PROBLEM: In many real applications that use and analyze networked data, the links in the network graph may be erroneous, or derived from probabilistic techniques. In such cases, the node classification problem can be challenging, since the unreliability of the links may affect the final results of the classification process. If the information about link reliability is not used explicitly, the classification accuracy in the underlying network may be affected adversely. In this paper, we focus on situations that require the analysis of the uncertainty that is present in the graph structure. We study the novel problem of node classification in uncertain graphs, by treating uncertainty as a first-class citizen. We propose two techniques based on a Bayes model and automatic parameter selection, and show that the incorporation of uncertainty in the classification process as a first-class citizen is beneficial. We experimentally evaluate the proposed approach using different real data sets, and study the behavior of the algorithms under different conditions. The results demonstrate the effectiveness and efficiency of our approach.

SOLUTION:
Node Classification in Uncertain Graphs