Detailed Instructions: Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
Problem:Paragraph: No mention of costs of bioidentical, transdermal, oral forms. Doesn't actually mention outcomes for which hormone therapy is being used, other than "keep feeling good" in the last paragraph. Given the lack of quality of life data for those taking hormone therapy, this deserves attention. Story addresses competing views on harms. Story cites review by American College of Obstetricians & Gynecologists that found no evidence of INCREASED efficacy or safety (not clear whether it found them to be AS effective or safe) No disease mongering Good use of multiple sources. Story notes FDA-approved non-oral forms; however, story doesn't compare their effectiveness w/compounded forms. Story makes clear that compounded hormones are not FDA-approved. FDA-approved transdermal forms long been available Claim: Hormones given through the skin are worth a look
Solution:
This story reports on the increasingly popularbut largely untestedso-called "bioidentical" or "compounded" hormones. This well-balanced piece balances opinion with fact, quoting leading researchers, clinicians in private practice, the American College of Obstetricians & Gynecologists, and a Wyeth spokeswoman to demonstrate the range of opinions (and dearth of hard evidence) about these products.