Given a scientific passage and an answer, generate a question for the given answer.
Example: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Example solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Example explanation: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

Problem: Passage: Mutation Mutations are changes to an organism's DNA and are an important driver of diversity in populations. Species evolve because of the accumulation of mutations that occur over time. The appearance of new mutations is the most common way to introduce novel genotypic and phenotypic variance. Some mutations are unfavorable or harmful and are quickly eliminated from the population by natural selection. Others are beneficial and will spread through the population. Whether or not a mutation is beneficial or harmful is determined by whether it helps an organism survive to sexual maturity and reproduce. Some mutations do not do anything and can linger, unaffected by natural selection, in the genome. Some can have a dramatic effect on a gene and the resulting phenotype. Answer: mutations
Solution: What term is used to describe changes to an organism's dna and are an important driver of diversity in populations?