Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

[Q]: Context: A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS,S/AS01 vaccine during 18 mo following vaccination at 11 African sites with varying malaria transmission. 6,537 infants aged 6-12 wk and 8,923 children aged 5-17 mo were randomized to receive three doses of RTS,S/AS01 or comparator vaccine. VE against clinical malaria in children during the 18 mo after vaccine dose 3 (per protocol) was 46% (95% CI 42% to 50%) (range 40% to 77%; VE, p<0.01 across all sites). VE during the 20 mo after vaccine dose 1 (intention to treat [ITT]) was 45% (95% CI 41% to 49%). VE against severe malaria, malaria hospitalization, and all-cause hospitalization was 34% (95% CI 15% to 48%), 41% (95% CI 30% to 50%), and 19% (95% CI 11% to 27%), respectively (ITT). VE against clinical malaria in infants was 27% (95% CI 20% to 32%, per protocol; 27% [95% CI 21% to 33%], ITT), with no significant protection against severe malaria, malaria hospitalization, or all-cause hospitalization. Post-vaccination anti-circumsporozoite antibody geometric mean titer varied from 348 to 787 EU/ml across sites in children and from 117 to 335 EU/ml in infants (per protocol). VE waned over time in both age categories (Schoenfeld residuals p<0.001). The number of clinical and severe malaria cases averted per 1,000 children vaccinated ranged across sites from 37 to 2,365 and from -1 to 49, respectively; corresponding ranges among infants were -10 to 1,402 and -13 to 37, respectively (ITT). Meningitis was reported as a serious adverse event in 16/5,949 and 1/2,974 children and in 9/4,358 and 3/2,179 infants in the RTS,S/AS01 and control groups, respectively. RTS,S/AS01 prevented many cases of clinical and severe malaria over the 18 mo after vaccine dose 3, with the highest impact in areas with the greatest malaria incidence. VE was higher in children than in infants, but even at modest levels of VE, the number of malaria cases averted was substantial. RTS,S/AS01 could be an important addition to current malaria control in Africa. www.ClinicalTrials.gov NCT00866619 Please see later in the article for the Editors' Summary.
Question: RTS S AS01 vaccine was developed to prevent which disease?
[A]: malaria

[Q]: Context: Coming off their divisional home win over the Cardinals, the 49ers flew to the Edward Jones Dome for a Week 2 divisional duel against their NFC West rival, the St. Louis Rams. In the first quarter, the Niners trailed early as Rams QB Marc Bulger completed a 12-yard TD pass to WR Torry Holt for the only score of the period. In the second quarter, San Francisco would tie the game up with RB Frank Gore getting a 1-yard TD run. St. Louis would take the halftime lead with kicker Jeff Wilkins getting a 29-yard field goal In the third quarter, the 49ers took the lead with Gore breaking through a gang of tacklers for a 43-yard TD run, along with the only score of the period. In the fourth quarter, the Rams retook the lead with Wiklins getting a 53-yard field goal. Fortunately, thanks to a St. Louis goof-up on special teams, the Niners took the lead with kicker Joe Nedney getting a 40-yard field goal. Near the end the game, the Rams had one last chance to win the game. Fortunately for San Francisco, Wilkins' 56-yard field goal attempt fell about a yard short of the crossbar. With the win, the 49ers improved to 2-0 for the first time since 1998. Q1 - STL - 6:04 - 12-yard TD pass from Marc Bulger to Torry Holt (Wilkins kick) (STL 7-0) Q2 - SF - 14:57 - Frank Gore 1-yard TD run (Nedney kick) (7-7) Q2 - STL - 9:04 - Jeff Wilkins 27-yard FG (STL 10-7) Q2 - STL - 1:51 - Jeff Wilkins 29-yard FG (STL 13-7) Q3 - SF - 2:43 - Frank Gore 43-yard TD run (Nedney kick) (SF 14-13) Q4 - STL - 10:04 - Jeff Wilkins 53-yard FG (STL 16-14) Q4 - SF - 3:23 - Joe Nedney 40-yard FG (SF 17-16)
Question: How did the 49ers take the lead in the fourth quarter?
[A]: joe nedney

[Q]: Context: Pirates of Treasure Island is a 2006 American comedy-drama film produced by The Asylum, loosely adaptated from Robert Louis Stevenson's novel Treasure Island.
Question: What studio produced Pirates of Treasure Island?
[A]:
the asylum