Teacher:Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Teacher: Now, understand the problem? Solve this instance: Question: Do amyloid and APOE 4 interact to influence short-term decline in preclinical Alzheimer disease?
Answer: Clinically normal individuals who are APOE 4+ and have high A showed the highest cognitive decline. These results suggest that A and APOE 4 are not redundant contributors of decline in aging but rather interact to promote decline during the short follow-up period examined in this study. Longer follow-up periods will be essential to fully elucidate the influence of Alzheimer disease risk factors on cognitive decline in aging.
Student:
yes