Given the task definition and input, reply with output. Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does peginterferon- improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis?
Answer: IFN- did not improve peripheral blood HBV-specific T-cell responses in the first 24 weeks of treatment, consistent either with a predominant antiviral/antiproliferative effect or with an immunomodulatory activity on other arms of the immune system which were not analyzed in our study. A better pre-treatment ex vivo IFN- production was associated with better chances to control HBV replication during therapy and represents a promising predictor of IFN efficacy.
no