Problem: Please answer a question about the following article about Pharmaceutical industry:
In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circumstances drugs and technologies will be made available by the NHS, whilst similar arrangements exist with the Scottish Medicines Consortium in Scotland, and the Pharmaceutical Benefits Advisory Committee in Australia. A product must pass the threshold for cost-effectiveness if it is to be approved. Treatments must represent 'value for money' and a net benefit to society.
What is the name of the organization in Scotland that decides the availability of drugs?
A: Scottish Medicines Consortium
Problem: Please answer a question about the following article about Pharmaceutical industry:
Drug discovery and development is very expensive; of all compounds investigated for use in humans only a small fraction are eventually approved in most nations by government appointed medical institutions or boards, who have to approve new drugs before they can be marketed in those countries. In 2010 18 NMEs (New Molecular Entities) were approved and three biologics by the FDA, or 21 in total, which is down from 26 in 2009 and 24 in 2008. On the other hand, there were only 18 approvals in total in 2007 and 22 back in 2006. Since 2001, the Center for Drug Evaluation and Research has averaged 22.9 approvals a year. This approval comes only after heavy investment in pre-clinical development and clinical trials, as well as a commitment to ongoing safety monitoring. Drugs which fail part-way through this process often incur large costs, while generating no revenue in return. If the cost of these failed drugs is taken into account, the cost of developing a successful new drug (new chemical entity, or NCE), has been estimated at about 1.3 billion USD(not including marketing expenses). Professors Light and Lexchin reported in 2012, however, that the rate of approval for new drugs has been a relatively stable average rate of 15 to 25 for decades.
Who reported the stable average rate in 2012?
A: Professors Light and Lexchin
Problem: Please answer a question about the following article about Antenna (radio):
The amount of signal received from a distant transmission source is essentially geometric in nature due to the inverse square law, and this leads to the concept of effective area. This measures the performance of an antenna by comparing the amount of power it generates to the amount of power in the original signal, measured in terms of the signal's power density in Watts per square metre. A half-wave dipole has an effective area of 0.13 2. If more performance is needed, one cannot simply make the antenna larger. Although this would intercept more energy from the signal, due to the considerations above, it would decrease the output significantly due to it moving away from the resonant length. In roles where higher performance is needed, designers often use multiple elements combined together.
What type of project would call for more than one element used together?
A: higher performance
Problem: Please answer a question about the following article about The Times:
In May 2008 printing of The Times switched from Wapping to new plants at Broxbourne on the outskirts of London, and Merseyside and Glasgow, enabling the paper to be produced with full colour on every page for the first time.
In May 2008, The Times switched to new plants which allowed for what kind of feature to be printed on every page for the first time?
A:
full colour