Given a scientific passage and an answer, generate a question for the given answer.

Let me give you an example: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
The answer to this example can be: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Here is why: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

OK. solve this:
Passage: Functionally, the respiratory system can be divided into a conducting zone and a respiratory zone. The conducting zone of the respiratory system includes the organs and structures not directly involved in gas exchange. The gas exchange occurs in the respiratory zone. Answer: gas exchange
Answer:
The conducting zone of the respiratory system includes the organs and structures not directly involved in what?