Problem: Royal Dutch Shell:

Through most of Shell's early history, the Shell Oil Company business in the United States was substantially independent with its stock being traded on the NYSE and with little direct involvement from the group's central offices in the running of the American business. However, in 1984, Royal Dutch Shell made a bid to purchase those shares of Shell Oil Company it did not own (around 30%) and despite opposition from some minority shareholders, which led to a court case, Shell completed the buyout for a sum of $5.7 billion.

Shell's early history involved a lot of involvement from what?
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A: unanswerable

Problem: The context for the rise of the public sphere was the economic and social change commonly associated with the Industrial Revolution: "economic expansion, increasing urbanization, rising population and improving communications in comparison to the stagnation of the previous century"." Rising efficiency in production techniques and communication lowered the prices of consumer goods and increased the amount and variety of goods available to consumers (including the literature essential to the public sphere). Meanwhile, the colonial experience (most European states had colonial empires in the 18th century) began to expose European society to extremely heterogeneous cultures, leading to the breaking down of "barriers between cultural systems, religious divides, gender differences and geographical areas".
Did rising efficiency in production and communication lower or raise the prices of consumer goods?
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Answer: lowered

Q: What is a question about this article? If the question is unanswerable, say "unanswerable".
During the Nimrod Expedition led by Ernest Shackleton in 1907, parties led by Edgeworth David became the first to climb Mount Erebus and to reach the South Magnetic Pole. Douglas Mawson, who assumed the leadership of the Magnetic Pole party on their perilous return, went on to lead several expeditions until retiring in 1931. In addition, Shackleton himself and three other members of his expedition made several firsts in December 1908 February 1909: they were the first humans to traverse the Ross Ice Shelf, the first to traverse the Transantarctic Mountains (via the Beardmore Glacier), and the first to set foot on the South Polar Plateau. An expedition led by Norwegian polar explorer Roald Amundsen from the ship Fram became the first to reach the geographic South Pole on 14 December 1911, using a route from the Bay of Whales and up the Axel Heiberg Glacier. One month later, the doomed Scott Expedition reached the pole.
What expedition was led by Edgeworth Shackleton?
A: unanswerable

Context and question: Shih-Shan Henry Tsai writes that the Yongle Emperor sent his eunuch Yang Sanbao into Tibet in 1413 to gain the allegiance of various Tibetan princes, while the Yongle Emperor paid a small fortune in return gifts for tributes in order to maintain the loyalty of neighboring vassal states such as Nepal and Tibet. However, Van Praag states that Tibetan rulers upheld their own separate relations with the kingdoms of Nepal and Kashmir, and at times "engaged in armed confrontation with them."
Why did the emperor pay a small fortune in gifts?
Answer: to maintain the loyalty of neighboring vassal states

Question: The Indonesian Archipelago is split by the Wallace Line. This line runs along what is now known to be a tectonic plate boundary, and separates Asian (Western) species from Australasian (Eastern) species. The islands between Java/Borneo and Papua form a mixed zone, where both types occur, known as Wallacea. As the pace of development accelerates and populations continue to expand in Southeast Asia, concern has increased regarding the impact of human activity on the region's environment. A significant portion of Southeast Asia, however, has not changed greatly and remains an unaltered home to wildlife. The nations of the region, with only few exceptions, have become aware of the need to maintain forest cover not only to prevent soil erosion but to preserve the diversity of flora and fauna. Indonesia, for example, has created an extensive system of national parks and preserves for this purpose. Even so, such species as the Javan rhinoceros face extinction, with only a handful of the animals remaining in western Java.
Is there an answer to this question: What is the concern in Southeast Asian region due to development & population expansion?

Answer: impact of human activity on the region's environment.

QUES: Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, enhancers increase transcription by binding an activator protein which then helps to recruit the RNA polymerase to the promoter; conversely silencers bind repressor proteins and make the DNA less available for RNA polymerase.

How do regulatory regions act?
What is the answer?
ANS:
by binding to transcription factors