IN: Jonas Edward Salk (; October 28, 1914 - June 23, 1995) was an American medical researcher and virologist. He discovered and developed one of the first successful polio vaccines. Born in New York City, he attended New York University School of Medicine, later choosing to do medical research instead of becoming a practicing physician. In 1939, after earning his medical degree, Salk began an internship as a physician scientist at Mount Sinai Hospital.

In 1947, Salk became ambitious for his own lab and was granted one at the University of Pittsburgh, but the lab was smaller than he had hoped and he found the rules imposed by the university restrictive. In 1948, Harry Weaver, the director of research at the National Foundation for Infantile Paralysis, contacted Salk. He asked Salk to find out if there were more types of polio than the three then known, offering additional space, equipment and researchers. For the first year he gathered supplies and researchers including Julius Youngner, Byron Bennett, L. James Lewis, and secretary Lorraine Friedman joined Salk's team, as well. As time went on, Salk began securing grants from the Mellon family and was able to build a working virology laboratory. He later joined the National Foundation for Infantile Paralysis's polio project established by President Franklin D. Roosevelt. Extensive publicity and fear of polio led to much increased funding, $67 million by 1955, but research continued on dangerous live vaccines. Salk decided to use the safer 'killed' virus, instead of weakened forms of strains of polio viruses like the ones used contemporarily by Albert Sabin, who was developing an oral vaccine. After successful tests on laboratory animals, on July 2, 1952, assisted by the staff at the D.T. Watson Home for Crippled Children, Salk injected 43 children with his killed-virus vaccine. A few weeks later, Salk injected children at the Polk State School for the retarded and feeble-minded. In 1954 he tested the vaccine on about one million children, known as the polio pioneers. The vaccine was announced as safe on April 12, 1955. The project became large, involving 100 million contributors to the March of Dimes, and 7 million volunteers. The foundation allowed itself to go into debt to finance the final research required to develop the Salk vaccine. Salk worked incessantly for two and a half years. Salk's inactivated polio vaccine was the first vaccine for the disease; it came into use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

When did he start doing Polio research?

OUT: In 1948, Harry Weaver, the director of research at the National Foundation for Infantile Paralysis, contacted Salk.

IN: O'Neill was born in a hotel, the Barrett House, at Broadway and 43rd Street, on what was then Longacre Square (now Times Square). A commemorative plaque was first dedicated there in 1957. The site is now occupied by 1500 Broadway, which houses offices, retail, and ABC Studios. He was the son of Irish immigrant actor James O'Neill and Mary Ellen Quinlan, who was also of Irish descent.

O'Neill was married to Kathleen Jenkins from October 2, 1909 to 1912, during which time they had one son, Eugene O'Neill, Jr. (1910-1950). In 1917, O'Neill met Agnes Boulton, a successful writer of commercial fiction, and they married on April 12, 1918. They lived in a home owned by her parents in Point Pleasant, New Jersey, after their marriage. The years of their marriage--during which the couple lived in Connecticut and Bermuda and had two children, Shane and Oona--are described vividly in her 1958 memoir Part of a Long Story. They divorced in 1929, after O'Neill abandoned Boulton and the children for the actress Carlotta Monterey (born San Francisco, California, December 28, 1888; died Westwood, New Jersey, November 18, 1970). O'Neill and Carlotta married less than a month after he officially divorced his previous wife. In 1929, O'Neill and Monterey moved to the Loire Valley in central France, where they lived in the Chateau du Plessis in Saint-Antoine-du-Rocher, Indre-et-Loire. During the early 1930s they returned to the United States and lived in Sea Island, Georgia, at a house called Casa Genotta. He moved to Danville, California in 1937 and lived there until 1944. His house there, Tao House, is today the Eugene O'Neill National Historic Site. In their first years together, Monterey organized O'Neill's life, enabling him to devote himself to writing. She later became addicted to potassium bromide, and the marriage deteriorated, resulting in a number of separations, although they never divorced. In 1943, O'Neill disowned his daughter Oona for marrying the English actor, director, and producer Charlie Chaplin when she was 18 and Chaplin was 54. He never saw Oona again. He also had distant relationships with his sons. Eugene O'Neill, Jr., a Yale classicist, suffered from alcoholism and committed suicide in 1950 at the age of 40. Shane O'Neill became a heroin addict and moved into the family home in Bermuda, Spithead, with his new wife, where he supported himself by selling off the furnishings. He was disowned by his father before also committing suicide (by jumping out of a window) a number of years later. Oona ultimately inherited Spithead and the connected estate (subsequently known as the Chaplin Estate). In 1950 O'Neill joined The Lambs, the famed theater club.

what is known about his family life?

OUT:
O'Neill was married to Kathleen Jenkins from October 2, 1909 to 1912,