In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Paragraph: The envelope spike (S) proteins of MERS-CoV and SARS-CoV determine the virus host tropism and entry into host cells, and constitute a promising target for the development of prophylactics and therapeutics. Here, we present high-resolution structures of the trimeric MERS-CoV and SARS-CoV S proteins in its pre-fusion conformation by single particle cryo-electron microscopy. The overall structures resemble that from other coronaviruses including HKU1, MHV and NL63 reported recently, with the exception of the receptor binding domain (RBD). We captured two states of the RBD with receptor binding region either buried (lying state) or exposed (standing state), demonstrating an inherently flexible RBD readily recognized by the receptor. Further sequence conservation analysis of six human-infecting coronaviruses revealed that the fusion peptide, HR1 region and the central helix are potential targets for eliciting broadly neutralizing antibodies.
Title: ARTICLE Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
False

Paragraph: Metabolomics aims to measure and characterise the complex composition of metabolites in a biological system. Metabolomics studies involve sophisticated analytical techniques such as mass spectrometry and nuclear magnetic resonance spectroscopy, and generate large amounts of 2 of 55 high-dimensional and complex experimental data. Open source processing and analysis tools are of major interest in light of innovative, open and reproducible science. The scientific community has developed a wide range of open source software, providing freely available advanced processing and analysis approaches. The programming and statistics environment R has emerged as one of the most popular environments to process and analyse Metabolomics datasets. A major benefit of such an environment is the possibility of connecting different tools into more complex workflows. Combining reusable data processing R scripts with the experimental data thus allows for open, reproducible research. This review provides an extensive overview of existing packages in R for different steps in a typical computational metabolomics workflow, including data processing, biostatistics, metabolite annotation and identification, and biochemical network and pathway analysis. Multifunctional workflows, possible user interfaces and integration into workflow management systems are also reviewed. In total, this review summarises more than two hundred metabolomics specific packages primarily available on CRAN, Bioconductor and GitHub.
Title: metabolites H OH OH The metaRbolomics Toolbox in Bioconductor and beyond
True

Paragraph: The photocatalytic activity of TiO 2 was enhanced by Ag metal doping. TiO 2 and Ag-doped TiO 2 were coated on porous polyurethane (PU) using C-Si-O-Ti bonds. Increased adsorption ability of the photocatalyst was due to the porosity of the PU. Removal of E. coli from an aerosol was only by adsorption with PU and TiO 2 /PU. Under visible light, E. coli was removed by adsorption and photo-oxidation with Ag-TiO 2 /PU. We investigated a novel approach by synthesizing an integrated material, which could act as both adsorbent and photocatalytic material, for bioaerosol purification under visible light conditions. Ag was used as a dopant agent to enhance photocatalytic activity of TiO 2 , leading to high photocatalytic activity of the doped TiO 2 even under visible light. Under visible light, the doped TiO 2 photocatalyst could produce oxy radicals, oxidative agents, that participate in oxidation reactions to decompose important organic components of bacteria, leading to death or removal of bacteria from an aerosol. Adsorption property was integrated into the enhanced TiO 2 photocatalyst by using polyurethane (PU), a honeycomb structure material, as a substrate for coating process of the doped TiO 2 . Three materials including pristine PU, TiO 2 coating on PU (TiO 2 /PU), and Ag-doped TiO 2 coating on PU (Ag-TiO 2 /PU) were used to remove Escherichia coli in an aerosol under visible light. Under dark conditions, the removal capacities of E. coli in the aerosol by PU, TiO 2 /PU, and Ag-TiO 2 /PU were 1.2 A 10 5 , 2.7 A 10 5 , and 6.2 A 10 5 (CFU/cm 3 ), respectively. Under visible light irradiation, the removal capacities of E. coli in an aerosol by PU, TiO 2 /PU, and Ag-TiO 2 /PU were 1.2 A 10 5 , 2.7 A 10 5 , and 1.8 A 10 6 (CFU/cm 3 ), respectively. The improvement of the removal capacity by TiO 2 /PU and Ag-TiO 2 /PU, versus PU, is due to adsorption alone and the combination of adsorption plus photocatalytic activity, respectively.
Title: Novel integrated approach of adsorption and photo-oxidation using Ag-TiO 2 /PU for bioaerosol removal under visible light
False