Teacher:In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Teacher: Now, understand the problem? Solve this instance: A temperature-sensitive mutant of vesicular stomatitis virus was inoculated intranasally into inlant Sprague Dawley rats aged 9 to 17 days. Rats receiving the virus at 9 days ol'age had an extensive spread of int'ection throughout the brain and the animals died after a few days. Rats inoculated at day I I postnatally survived and the infection was limited to the olfactory pathways, hypothalamus, diagonal bands and the anterior raphe nuclei. Stereological measurements showed that the volume of infected neurons constituted 67+ 10% of the total neuronal volume in the dorsal raphe nucleus. Doublelabelling experiments revealed that both 5-hydroxytryptamine-and substance P-immunoreactive neurons contained the virus antigen. The motor stimulant effect of amphetamine was studied at 3 months post infection. The increase in amphetamine-induced frequency and duration of rearing was significantly attenuated in infected rats and the amphetamine-induced locomotion was slightl~ reduced. KI Y W(IRI)N: Virus infection 5-Hydroxytryptaminc Immunohistochemislrv
Student:
Immunohistochemical and Behaviour Pharmacological Analysis of Rats Inoculated Intranasally with Vesicular Stomatitis Virus