TASK DEFINITION: In this task, you are given a context, a subject, a relation, and many options. Based on the context, from the options select the object entity that has the given relation with the subject. Answer with text (not indexes).
PROBLEM: Context: Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body. This may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months.
While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.
The goal of treatment is to reduce pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs), such as hydroxychloroquine and methotrexate, may be used to try to slow the progression of disease. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fuse joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.
RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013, it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landre-Beauvais (17721840) of Paris. The term "rheumatoid arthritis" is based on the Greek for watery and inflamed joints.
Signs and symptoms.
RA primarily affects joints, but it also affects other organs in more than 1525% of individuals., Fibromyalgia (FM) is a medical condition characterised by chronic widespread pain and a heightened pain response to pressure. Other symptoms include feeling tired to a degree that normal activities are affected, sleep problems, and troubles with memory. Some people also report restless legs syndrome, bowel or bladder problems, numbness and tingling, and sensitivity to noise, lights or temperature. Fibromyalgia is frequently associated with depression, anxiety, and posttraumatic stress disorder. Other types of chronic pain are also frequently present.
The cause of fibromyalgia is unknown; however, it is believed to involve a combination of genetic and environmental factors with half the risk attributed to each. The condition runs in families and many genes are believed to be involved. Environmental factors may include psychological stress, trauma, and certain infections. The pain appears to result from processes in the central nervous system and the condition is referred to as a "central sensitization syndrome". Fibromyalgia is recognized as a disorder by the US National Institutes of Health and the American College of Rheumatology. There is no specific diagnostic test. Diagnosis involves first ruling out other potential causes and verifying that a set number of symptoms are present.
The treatment of fibromyalgia can be difficult. Recommendations often include getting enough sleep, exercising regularly, and eating a healthy diet. Cognitive behavioral therapy may also be helpful. The medications duloxetine, milnacipran, or pregabalin may be used. Use of opioid pain medication is controversial with some stating their use is poorly supported by evidence and others saying that weak opioids may be reasonable if other medications are not effective. Dietary supplements also lack evidence to support their use. While fibromyalgia can last a long time, it does not result in death or tissue damage.
Fibromyalgia is estimated to affect 28% of the population. Females are affected about twice as often as males. Rates appear similar in different areas of the world and among different cultures. Fibromyalgia was first defined in 1990 with updated criteria in 2011. There is controversy about the classification, diagnosis, and treatment of fibromyalgia. While some feel the diagnosis of fibromyalgia may negatively affect a person, other research finds it to be beneficial. The term "fibromyalgia" is from New Latin, "fibro-", meaning "fibrous tissues", Greek "myo-", "muscle", and Greek "algos", "pain"; thus the term literally means "muscle and fibrous connective tissue pain"., A burn is a type of injury to skin, or other tissues, caused by heat, cold, electricity, chemicals, friction, or radiation. Most burns are due to heat from hot liquids, solids, or fire. Females in many areas of the world have a higher risk related to the more frequent use of open cooking fires or unsafe cook stoves. Alcoholism and smoking are other risk factors. Burns can also occur as a result of self harm or violence between people.
Burns that affect only the superficial skin layers are known as superficial or first-degree burns. They appear red without blisters and pain typically lasts around three days. When the injury extends into some of the underlying skin layer, it is a partial-thickness or second-degree burn. Blisters are frequently present and they are often very painful. Healing can require up to eight weeks and scarring may occur. In a full-thickness or third-degree burn, the injury extends to all layers of the skin. Often there is no pain and the burn area is stiff. Healing typically does not occur on its own. A fourth-degree burn additionally involves injury to deeper tissues, such as muscle, tendons, or bone. The burn is often black and frequently leads to loss of the burned part.
Burns are generally preventable. Treatment depends on the severity of the burn. Superficial burns may be managed with little more than simple pain medication, while major burns may require prolonged treatment in specialized burn centers. Cooling with tap water may help pain and decrease damage; however, prolonged cooling may result in low body temperature. Partial-thickness burns may require cleaning with soap and water, followed by dressings. It is not clear how to manage blisters, but it is probably reasonable to leave them intact if small and drain them if large. Full-thickness burns usually require surgical treatments, such as skin grafting. Extensive burns often require large amounts of intravenous fluid, due to capillary fluid leakage and tissue swelling. The most common complications of burns involve infection. Tetanus toxoid should be given if not up to date.
In 2013, fire and heat resulted in 35 million injuries. This resulted in about 2.9 million hospitalizations and 238,000 dying. Most deaths due to burns occur in the developing world, particularly in Southeast Asia. While large burns can be fatal, treatments developed since 1960 have improved outcomes, especially in children and young adults. In the United States, approximately 96% of those admitted to a burn center survive their injuries. Burns occur at similar frequencies in men and women. The long-term outcome is related to the size of burn and the age of the person affected.
Signs and symptoms.
The characteristics of a burn depend upon its depth. Superficial burns cause pain lasting two or three days, followed by peeling of the skin over the next few days. Individuals suffering from more severe burns may indicate discomfort or complain of feeling pressure rather than pain. Full-thickness burns may be entirely insensitive to light touch or puncture. While superficial burns are typically red in color, severe burns may be pink, white or black. Burns around the mouth or singed hair inside the nose may indicate that burns to the airways have occurred, but these findings are not definitive. More worrisome signs include: shortness of breath, hoarseness, and stridor or wheezing. Itchiness is common during the healing process, occurring in up to 90% of adults and nearly all children. Numbness or tingling may persist for a prolonged period of time after an electrical injury. Burns may also produce emotional and psychological distress., Orthopedic surgery or orthopedics (alternatively spelled orthopaedic surgery and orthopaedics) is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal trauma, spine diseases, sports injuries, degenerative diseases, infections, tumors, and congenital disorders.
Etymology.
Nicholas Andry coined the word ""orthopdics"" in French as "orthopedie", derived from the Greek words "orthos" ("correct", "straight") and "paidion" ("child"), when he published "Orthopedie" (translated as "Orthopdia: or the Art of Correcting and Preventing Deformities in Children") in 1741. Though as the name implies it was initially developed with attention to children, the correction of spinal and bony deformities in all stages of life eventually became the cornerstone of orthopedic practice., Septic arthritis, also known as infectious arthritis or joint infection, is the purulent invasion of a joint by an infectious agent which produces arthritis. People with artificial joints are more at risk than the general population but have slightly different symptoms, are infected with different organisms and require different treatment. Septic arthritis is considered a medical emergency. If untreated, it may destroy the joint in a period of days. The infection may also spread to other parts of the body., Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types other organs are also affected. Onset can be gradual or sudden.
There are over 100 types of arthritis. The most common forms are osteoarthritis (degenerative joint disease) and rheumatoid arthritis. Osteoarthritis usually occurs with age and affects the fingers, knees, and hips. Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. Other types include gout, lupus, fibromyalgia, and septic arthritis. They are all types of rheumatic disease.
Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be useful. Pain medications such as ibuprofen and paracetamol (acetaminophen) may be used. In some a joint replacement may be useful.
Osteoarthritis affects more than 3.8% of people while rheumatoid arthritis affects about 0.24% of people. Gout affects about 1 to 2% of the Western population at some point in their lives. In Australia about 15% of people are affected, while in the United States more than 20% of have a type of arthritis. Overall the disease becomes more common with age. Arthritis is a common reason that people miss work and can result in a decreased quality of life. The term is from Greek "arthro-" meaning joint and "-itis" meaning inflammation., A bone is a rigid organ that constitutes part of the vertebrate skeleton. Bones support and protect the various organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have a complex internal and external structure. They are lightweight yet strong and hard, and serve multiple functions. , Pain is a distressing feeling often caused by intense or damaging stimuli, such as stubbing a toe, burning a finger, putting alcohol on a cut, or bumping the "funny bone". Because it is a complex, subjective phenomenon, defining pain has been a challenge. The International Association for the Study of Pain's widely used definition states: "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." In medical diagnosis, pain is regarded as a symptom of an underlying condition., A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The study of disease is called pathology which includes the causal study of etiology. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens, or it may be caused by internal dysfunctions particularly of the immune system such as an immunodeficiency, or a hypersensitivity including allergies and autoimmunity., Replacement arthroplasty (from Greek "arthron", joint, limb, articulate, + "plassein", to form, mould, forge, feign, make an image of), or joint replacement surgery, is a procedure of orthopedic surgery in which an arthritic or dysfunctional joint surface is replaced with an orthopedic prosthesis. Joint replacement is considered as a treatment when severe joint pain or dysfunction is not alleviated by less-invasive therapies. During the latter half of the 20th century, rheumasurgery developed as a subspecialty focused on these and a few other procedures in patients with rheumatic diseases., White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system., Osteoarthritis ( OA ) is a type of joint disease that results from breakdown of joint cartilage and underlying bone . The most common symptoms are joint pain and stiffness . Initially , symptoms may occur only following exercise , but over time may become constant . Other symptoms may include joint swelling , decreased range of motion , and when the back is affected weakness or numbness of the arms and legs . The most commonly involved joints are those near the ends of the fingers , at the base of the thumb , neck , lower back , knees , and hips . Joints on one side of the body are often more affected than those on the other . Usually the problems come on over years . It can affect work and normal daily activities . Unlike other types of arthritis , only the joints are typically affected . Causes include previous joint injury , abnormal joint or limb development , and inherited factors . Risk is greater in those who are overweight , have one leg of a different length , and have jobs that result in high levels of joint stress . Osteoarthritis is believed to be caused by mechanical stress on the joint and low grade inflammatory processes . It develops as cartilage is lost with eventually the underlying bone becoming affected . As pain may make it difficult to exercise , muscle loss may occur . Diagnosis is typically based on signs and symptoms with medical imaging and other tests occasionally used to either support or rule out other problems . Unlike in rheumatoid arthritis , which is primarily an inflammatory condition , the joints do not typically become hot or red . Treatment includes exercise , efforts to decrease joint stress , support groups , and pain medications . Efforts to decrease joint stress include resting and the use of a cane . Weight loss may help in those who are overweight . Pain medications may include paracetamol ( acetaminophen ) . If this does not work NSAIDs such as naproxen may be used , but these medications are associated with greater side effects . Opioids if used are generally only recommended short term due to the risk of addiction . If pain interferes with normal life despite other treatments , joint replacement surgery may help . An artificial joint , however , only lasts a limited amount of time . Outcomes for most people with osteoarthritis are good . OA is the most common form of arthritis with disease of the knee and hip affecting about 3.8 % of people as of 2010 . Among those over 60 years old about 10 % of males and 18 % of females are affected . It is the cause of about 2 % of years lived with disability . In Australia about 1.9 million people are affected , and in the United States about 27 million people are affected . Before 45 years of age it is more common in men , while after 45 years of age it is more common in women . It becomes more common in both sexes as people become older ., Pathology (from the Greek roots of "pathos", meaning "experience" or "suffering", and "-logia", "study of") is a significant component of the causal study of disease and a major field in modern medicine and diagnosis., Medical imaging is the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging., Subject: osteoarthritis, Relation: medical_specialty, Options: (A) infection (B) infectious disease (C) orthopedics (D) pathology (E) rheumatology (F) surgery

SOLUTION: rheumatology

PROBLEM: Context: The Godfather Returns is a novel written by author Mark Winegardner, published in 2004. It is the sequel to Mario Puzo's "The Godfather", which was originally published in 1969, and "The Sicilian" (1984). The publisher, Random House, selected Winegardner to write a sequel after Puzo's death. As the original novel covered the years 1945 to 1955, and included significant back story on Don Vito Corleone's life, "Returns" covers the years 1955 to 1962, and includes significant back story on Michael Corleone's life prior to the first novel., Vito Andolini Corleone is a fictional character in Mario Puzo's novel "The Godfather" and in Francis Ford Coppola's film series based on the novel, where he was portrayed by Marlon Brando in "The Godfather" and, as a young man, by Robert De Niro in "The Godfather Part II"., Mark Winegardner (born November 24, 1961) is an American writer born and raised in Bryan, Ohio. His novels include "The Godfather Returns", "Crooked River Burning", and "The Veracruz Blues". He published a collection of short stories, "That's True of Everybody", in 2002. His newest novel, "The Godfather's Revenge", was published in November 2006 by Putnam. His "Godfather" novels continue the story of the Corleone family depicted in Mario Puzo's "The Godfather"., Mario Gianluigi Puzo (October 15, 1920 July 2, 1999) was an American author, screenwriter and journalist of Italian descent. He is known for his crime novels about the Mafia, most notably "The Godfather" (1969), which he later co-adapted into a three-part film saga directed by Francis Ford Coppola. He received the Academy Award for Best Adapted Screenplay for the first film in 1972 and "Part II" in 1974. Puzo also wrote the original screenplay for the 1978 "Superman" film. His last novel, "The Family", was released posthumously in 2001., Organized crime is a category of transnational, national, or local groupings of highly centralized enterprises run by criminals who intend to engage in illegal activity, most commonly for money and profit. Some criminal organizations, such as terrorist groups, are politically motivated. Sometimes criminal organizations force people to do business with them, such as when a gang extorts money from shopkeepers for so-called "protection". Gangs may become disciplined enough to be considered "organized". A criminal organization or gang can also be referred to as a mafia, mob, or crime syndicate; the network, subculture and community of criminals may be referred to as the underworld., Bryan is a city in and the county seat of Williams County, Ohio, United States, in the state's northwestern corner. The population was 8,545 at the 2010 census., The Godfather's Revenge, a 2006 novel written by author Mark Winegardner, is the sequel to "The Godfather", "The Sicilian", and "The Godfather Returns". The story takes place from 19631964, and picks up the story from where "The Godfather Returns" left off. The novel deals with Michael Corleone's guilt over the events of "The Godfather Part II", particularly his ordering the death of his brother, Fredo. Subplots include Nick Geraci's plans for revenge against the Corleones, Tom Hagen's being implicated in a murder, and organized crime's battle with a presidential family (the Sheas, who are analogous to the Kennedy family)., The Sicilian is a novel by Italian-American author Mario Puzo. Published in 1984 by Random House Publishing Group (ISBN 0-671-43564-7), it is based on Puzo's most famous work, "The Godfather". It is regarded as "The Godfather"'s literary sequel., Random House is the largest general-interest paperback publisher in the world.
As of 2013, it is part of Penguin Random House, which is jointly owned by German media conglomerate Bertelsmann and British global education and publishing company Pearson PLC., The Godfather Part II is a 1974 American crime film produced and directed by Francis Ford Coppola from a screenplay co-written with Mario Puzo, starring Al Pacino and Robert De Niro. Partially based on Puzo's 1969 novel "The Godfather", the film is both sequel and prequel to "The Godfather", presenting parallel dramas: one picks up the 1958 story of Michael Corleone (Pacino), the new Don of the Corleone crime family, protecting the family business in the aftermath of an attempt on his life; the prequel covers the journey of his father, Vito Corleone (De Niro), from his Sicilian childhood to the founding of his family enterprise in New York City., Tom Hagen is a fictional character in Mario Puzo's novel "Godfather" and Francis Ford Coppola's films "The Godfather" and "The Godfather Part II". He was portrayed by Robert Duvall in the films., Fausto Dominick ' Nick ' Geraci Jr. is a central character in the Mark Winegardner novels The Godfather Returns and The Godfather 's Revenge ., Michael Corleone is the main protagonist of Mario Puzo's novel "The Godfather" and the three Godfather films directed by Francis Ford Coppola. He was portrayed in the three films by Al Pacino, who was twice nominated for Academy Awards for the part., The Kennedy family is an American family that has been prominent in American politics, public service, and business during the 20th century. At least one Kennedy family member held federal elective office in every year between 1947 and 2011, and then from 2013 onwards, a span of time comprising more than a quarter of the nation's existence. Three of the four sons of Joseph, Sr. and Rose Kennedy served as Senator, and later ran for the presidency., Subject: nick geraci, Relation: instance_of, Options: (A) academy (B) battle (C) category (D) census (E) century (F) character (G) city (H) county (I) crime (J) criminal (K) criminal organization (L) death (M) descent (N) education (O) enterprise (P) family (Q) family business (R) fictional character (S) film (T) force (U) gang (V) group (W) house (X) journalist (Y) may (Z) murder ([) novel (\) november (]) october (^) office (_) organization (') organized crime (a) part (b) population (c) presidency (d) profit (e) protagonist (f) public (g) publisher (h) publishing (i) river (j) saga (k) seat (l) sequel (m) subculture (n) syndicate (o) three (p) underworld

SOLUTION: fictional character

PROBLEM: Context: Brighton and Hove is a city in East Sussex, in South East England. At the 2011 census, it was England's most populous seaside resort with a population of 273,400., Petworth House in the parish of Petworth, West Sussex, England, is a late 17th-century Grade I listed country house, rebuilt in 1688 by Charles Seymour, 6th Duke of Somerset, and altered in the 1870s to the design of the architect Anthony Salvin. It contains intricate wood-carvings by Grinling Gibbons (d.1721). It is the manor house of the manor of Petworth. For centuries it was the southern home for the Percy family, Earls of Northumberland. Petworth is famous for its extensive art collection made by George Wyndham, 3rd Earl of Egremont (1751-1837), containing many works by his friend Turner. It also has an expansive deer park, landscaped by Capability Brown, which contains the largest herd of fallow deer in England., House music is a genre of electronic music created by club DJs and music producers that originated in Chicago in the early 1980s. Early house music was generally dance-based music characterized by repetitive 4/4 beats, rhythms mainly provided by drum machines, off-beat hi-hat cymbals, and synthesized basslines. While house displayed several characteristics similar to disco music, it was more electronic and minimalistic, and the repetitive rhythm of house was more important than the song itself. House music initially became popular in Chicago clubs in 1984, pioneered by figures such as Frankie Knuckles, Phuture, Kym Mazelle, and Mr. Fingers, and was associated with African-American and gay subcultures. House music quickly spread to other American cities such as Detroit, New York City, Baltimore, and Newark all of which developed their own regional scenes. In the mid-to-late 1980s, house music became popular in Europe as well as major cities in South America, and Australia., Deconstruction Records is a British record label founded in 1987 by Pete Hadfield and Keith Blackhurst, together with Mike Pickering of M People. According to "DJ Magazine" it is "best remembered for marrying underground credibility and diversity with an open-minded attitude towards pop"., Godskitchen is an international superclub brand which is associated with dance music and organises events, particularly in the UK and US. The company used to run a club night of the same name at their nightclub AIR, in Birmingham. Godskitchen has an in-house music label. This label annually releases compilation albums, in addition to supporting new artists whom they believe bring something new to the genre., Surrey is a county in the south east of England and also one of the home counties bordering Greater London. Surrey shares borders with Kent to the east, East Sussex to the south-east, West Sussex to the south, Hampshire to the west and south-west and Berkshire to the north-west. The county town is Guildford. Surrey County Council sits extraterritorially at Kingston upon Thames, administered as part of Greater London since 1965. With a resident population of 1.1 million, Surrey is the most densely populated and third most populated county in the South East region, after Kent and Hampshire., DJ Magazine (also known as DJ Mag) is a British monthly magazine dedicated to electronic dance music and DJs. Founded in 1991, the magazine is adapted for distribution in UK, USA, Spain, France, Italy, Latin America, China, South Korea and Indonesia., Superclub is a term used to refer to a nightclub owned and managed by a dance music record label, such as anything other than Liquid in Portsmouth. EG The Hacienda club, which was owned by Factory Records. The term has also been used to describe large, multistory, high-capacity high-profile nightclubs, such as Pacha in Ibiza, or 1970s discotheques such as New York City's Studio 54 (opened in 1977) and The Saint (opened in 1980), and London's Heaven (opened in 1979), which were earlier versions of the genre., Scott Bond is a trance music artist, producer, and promoter from Birmingham, England, who began DJing in 1989. He started out DJing at venues such as Cream, Miss Moneypenny's, Fun and Gatecrasher, which he co-founded. He has toured internationally with Gatecrasher. He was voted World's Finest Resident DJ in the Mixmag Dance Awards., Birmingham is a major city and metropolitan borough of West Midlands, England. It is the largest and most populous British city outside London, with a population in 2014 of 1,101,360. The city is in the West Midlands Built-up Area, the third most populous urban area in the United Kingdom, with a population of 2,440,986 at the 2011 census. Birmingham's metropolitan area is the second most populous in the UK with a population of 3.8 million. This also makes Birmingham the 9th most populous metropolitan area in Europe., Arundel Castle is a restored and remodeled medieval castle in Arundel, West Sussex, England. It was established by Roger de Montgomery on Christmas Day 1068. Roger became the first to hold the earldom of Arundel by the graces of William the Conqueror. The castle was damaged in the English Civil War and then restored in the 18th and 19th centuries., Worthing is a large seaside town in England, with borough status in West Sussex, in the historic county of Sussex. It is situated at the foot of the South Downs, west of Brighton, and east of the county town of Chichester. With an estimated population of 104,600 and an area of the borough is the second largest component of the Brighton/Worthing/Littlehampton conurbation, which makes it part of the 15th most populous urban area in the United Kingdom., England is a country that is part of the United Kingdom. It shares land borders with Scotland to the north and Wales to the west. The Irish Sea lies northwest of England and the Celtic Sea lies to the southwest. England is separated from continental Europe by the North Sea to the east and the English Channel to the south. The country covers five-eighths of the island of Great Britain (which lies in the North Atlantic) in its centre and south; and includes over 100 smaller islands such as the Isles of Scilly, and the Isle of Wight., Sussex (abbreviated Sx), from the Old English "Ssaxe" (South Saxons), is a historic county in South East England corresponding roughly in area to the ancient Kingdom of Sussex. It is bounded to the west by Hampshire, north by Surrey, north-east by Kent, south by the English Channel, and divided for local government into West Sussex and East Sussex and the city of Brighton and Hove. Brighton and Hove was created as a unitary authority in 1997, and granted City status in 2000. Until then, Chichester was Sussex's only city., John Fleming / flm / ( or John '' 00 '' Fleming ; born 1 April 1973 ) is an English trance producer and DJ from Worthing , West Sussex . He has had releases on record labels such as Ministry of Sound , Deconstruction Records , Logic Records , and 3 Beat Music . He also owns and runs Joof Recordings . He has performed at many clubs including Cream , Gatecrasher , Ministry of Sound , and Godskitchen . In his early 20s , Fleming battled lung cancer . Fleming was originally involved in goa music , but changed over to harder trance music before shifting to psychedelic trance . He traces his influences back to early 1990s acts such as Astral Projection and Juno Reactor . Global Trance Grooves is his monthly mix broadcast on Digitally Imported ., M People are an English dance music band which formed in 1990 and achieved success throughout most of the 1990s. The name M People is short for Manchester People, who formed the group. In December 2016, "Billboard magazine" ranked them as the 83rd most successful dance artists of all-time., Crawley is a town and borough in West Sussex, England. It is south of Charing Cross (London), north of Brighton and Hove, and north-east of the county town of Chichester. Crawley covers an area of and had a population of 106,597 at the time of the 2011 Census., Gatecrasher One was a nightclub in Sheffield, South Yorkshire, England. The club was a converted warehouse owned by the Gatecrasher dance music brand. The nightclub was originally named The Republic, but this was changed in 2003 after a 1.5million refurbishment. On 18 June 2007 the venue caught fire and partially collapsed. The building was later demolished., Michael Pickering (born 24 February 1958, Accrington, Lancashire, England) has DJed at The Hacienda's infamous "Nude" and "Hot" nights and later "Shine". He worked for Factory Records where he signed Happy Mondays, To Hell With Burgundy and James amongst others. He was the founder, writer and producer of Quando Quango and later M People, playing the saxophone, and as backing singer., West Sussex is a county in the south of England, bordering East Sussex (with Brighton and Hove) to the east, Hampshire to the west and Surrey to the north, and to the south the English Channel. Chichester in the southwest is the county town and only city in West Sussex, with the largest towns being Crawley, Worthing and Horsham.
West Sussex has a range of scenery, including wealden, downland and coastal. The highest point of the county is Blackdown, at 280 metres (919ft). It has a number of stately homes including Goodwood, Petworth House and Uppark and also castles such as Arundel Castle and Bramber Castle. Over half the county is protected countryside, offering walking, cycling and other recreational opportunities., Sheffield is a city and metropolitan borough in South Yorkshire, England. Historically part of the West Riding of Yorkshire, its name derives from the River Sheaf, which runs through the city. With some of its southern suburbs annexed from Derbyshire, the city has grown from its largely industrial roots to encompass a wider economic base. The population of the City of Sheffield is and it is one of the eight largest regional English cities that make up the Core Cities Group. Sheffield is the third largest English district by population. The metropolitan population of Sheffield is 1,569,000., Petworth is a small town and civil parish in the Chichester District of West Sussex, England. It is located at the junction of the A272 east-west road from Heathfield to Winchester and the A283 Milford to Shoreham-by-Sea road. Some twelve miles (21km) to the south west of Petworth along the A285 road lies Chichester and the south-coast. The parish includes the settlements of Byworth and Hampers Green and covers an area of . In 2001 the population of the parish was 2,775 persons living in 1,200 households of whom 1,326 were economically active. At the 2011 Census the population was 3,027., Gatecrasher is an international clubbing brand made famous by the "Gatecrasher" (later "Crasher") dance music events, which were held at the Gatecrasher One nightclub in Sheffield, UK during the late 1990s and early 2000s. The promoters of the brand are Simon Raine, Simon Oates and, until 2004, Scott Bond. As of August 2014, the only Gatecrasher venue remaining was located in the United Kingdom (UK) city of Birmingham which was closed down permanently by the authorities on November 25, 2015.
The site of Gatecrasher Birmingham on Broad street were acquired by Deltic (formerly called Luminar Leisure) who are to turn the venue into their Pryzm brand in the summer of 2016., Hampshire (; abbreviated Hants, archaically known as the County of Southampton) is a county on the southern coast of England in the United Kingdom. The county town of Hampshire is Winchester, the former capital city of England. Hampshire is the most populous ceremonial county in the United Kingdom (excluding the metropolitan counties) with almost half of the county's population living within the South Hampshire conurbation which includes the cities of Southampton and Portsmouth. The larger South Hampshire metropolitan area has a population of 1,547,000. Hampshire is notable for housing the birthplaces of the Royal Navy, British Army, and Royal Air Force. It is bordered by Dorset to the west, Wiltshire to the north-west, Berkshire to the north, Surrey to the north-east, and West Sussex to the east. The southern boundary is the coastline of the English Channel and the Solent, facing the Isle of Wight., Subject: john fleming , Relation: date_of_birth, Options: (A) 1 (B) 100 (C) 104 (D) 1068 (E) 1688 (F) 1721 (G) 1751 (H) 1837 (I) 1958 (J) 1965 (K) 1977 (L) 1979 (M) 1980 (N) 1984 (O) 1987 (P) 1989 (Q) 1990 (R) 1991 (S) 1997 (T) 2 (U) 2000 (V) 2001 (W) 2003 (X) 2004 (Y) 25 (Z) 273 ([) 280 (\) 360 (]) 4 (^) 547 (_) 597 (') 600 (a) 775 (b) 919

SOLUTION:
2000