Generate a correct and concise answer for the question based on the words in the context.
Q: Context : Melanie de Salignac (Marennes, Charente-Maritime, 19 January 1744 --1766) was a young French woman whose achievements in the face of her disability - blindness - were mentioned in the accounts of Diderot.
Question : What illness negatively impacted Melanie de Salignac?
A:
blindness