Others have argued that excessive regulation suppresses therapeutic innovation, and that the current cost of regulator-required clinical trials prevents the full exploitation of new genetic and biological knowledge for the treatment of human disease. A 2012 report by the President's Council of Advisors on Science and Technology made several key recommendations to reduce regulatory burdens to new drug development, including 1) expanding the FDA's use of accelerated approval processes, 2) creating an expedited approval pathway for drugs intended for use in narrowly defined populations, and 3) undertaking pilot projects designed to evaluate the feasibility of a new, adaptive drug approval process.
In what year was a report made to reduce the burdens of drug development?
2012

Input: East Prussia
Since 1875, with the strengthening of self-rule, the urban and rural districts (Kreise) within each province (sometimes within each governorate) formed a corporation with common tasks and assets (schools, traffic installations, hospitals, cultural institutions, jails etc.) called the Provinzialverband (provincial association). Initially the assemblies of the urban and rural districts elected representatives for the provincial diets (Provinziallandtage), which were thus indirectly elected. As of 1919 the provincial diets (or as to governorate diets, the so-called Kommunallandtage) were directly elected by the citizens of the provinces (or governorates, respectively). These parliaments legislated within the competences transferred to the provincial associations. The provincial diet of East Prussia elected a provincial executive body (government), the provincial committee (Provinzialausschuss), and a head of province, the Landeshauptmann ("Land Captain"; till the 1880s titled Landdirektor, land director).

What were common task of the corporation formed by the urban and rural districts?
Output: schools, traffic installations, hospitals, cultural institutions, jails

Input: Article: On the Origin of Species, published on 24 November 1859, is a work of scientific literature by Charles Darwin which is considered to be the foundation of evolutionary biology. Darwin's book introduced the scientific theory that populations evolve over the course of generations through a process of natural selection. It presented a body of evidence that the diversity of life arose by common descent through a branching pattern of evolution. Darwin included evidence that he had gathered on the Beagle expedition in the 1830s and his subsequent findings from research, correspondence, and experimentation.

Now answer this question: How do populations evolve according to Charles Darwin's theory?

Output: through a process of natural selection

Article: Palermo (Italian: [palrmo] ( listen), Sicilian: Palermu, Latin: Panormus, from Greek: , Panormos, Arabic: , Balarm; Phoenician: , Ziz) is a city in Insular Italy, the capital of both the autonomous region of Sicily and the Province of Palermo. The city is noted for its history, culture, architecture and gastronomy, playing an important role throughout much of its existence; it is over 2,700 years old. Palermo is located in the northwest of the island of Sicily, right by the Gulf of Palermo in the Tyrrhenian Sea.

Question: How old is the city of Palermo?
Ans: 2,700 years old

Here is a question about this article: The gut is generally an almost straight tube supported by the mesenteries (vertical partitions within segments), and ends with the anus on the underside of the pygidium. However, in members of the tube-dwelling family Siboglinidae the gut is blocked by a swollen lining that houses symbiotic bacteria, which can make up 15% of the worms' total weight. The bacteria convert inorganic matter such as hydrogen sulfide and carbon dioxide from hydrothermal vents, or methane from seeps to organic matter that feeds themselves and their hosts, while the worms extend their palps into the gas flows to absorb the gases needed by the bacteria.
What is the answer to this question: What type of annelids are tube-dwelling?
****
So... Siboglinidae

Article: With the financial expansion, trading rights became more jealously guarded by the commercial elite. Towns saw the growing power of guilds, while on a national level special companies would be granted monopolies on particular trades, like the English wool Staple. The beneficiaries of these developments would accumulate immense wealth. Families like the Fuggers in Germany, the Medicis in Italy, the de la Poles in England, and individuals like Jacques Coeur in France would help finance the wars of kings, and achieve great political influence in the process.

Question: Which economic associations gained power in the towns?
Ans:
guilds