Given a scientific passage and an answer, generate a question for the given answer.

Input: Consider Input: Passage: 41.4 Nitrogenous Wastes Ammonia is the waste produced by metabolism of nitrogen-containing compounds like proteins and nucleic acids. While aquatic animals can easily excrete ammonia into their watery surroundings, terrestrial animals have evolved special mechanisms to eliminate the toxic ammonia from their systems. Urea is the major byproduct of ammonia metabolism in vertebrate animals. Uric acid is the major byproduct of ammonia metabolism in birds, terrestrial arthropods, and reptiles. Answer: urea

Output: When vertebrate animals metabolize ammonia what is the primary byproduct that is produced?

Input: Consider Input: Passage: The largest known virus, called mimivirus, is so large that scientists first mistook it for a bacterium. It was first discovered in amoeba, in 1992, and was identified as a virus in 2003. Scientists believe that mimivirus may cause certain types of pneumonia in humans. The core contains DNA, with the majority of the DNA in genes, and only 10% DNA of unknown function ("junk" DNA). Answer: mimivirus

Output: What is the largest known virus?

Input: Consider Input: Passage: The proportionality between the rate and becomes an equal sign by the insertion of a constant . A rate law is an expression showing the relationship of the reaction rate to the concentrations of each reactant. The specific rate constant is the proportionality constant relating the rate of the reaction to the concentrations of reactants. The rate law and the specific rate constant for any chemical reaction must be determined experimentally. The value of the rate constant is temperature dependent. A large value of the rate constant means that the reaction is relatively fast, while a small value of the rate constant means that the reaction is relatively slow. Answer: rate law
Output: What is the term for an expression showing the relationship of the reaction rate to the concentrations of each reactant?