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A 2009 Cochrane review concluded that thiazide antihypertensive drugs reduce the risk of death (RR 0.89), stroke (RR 0.63), coronary heart disease (RR 0.84), and cardiovascular events (RR 0.70) in people with high blood pressure. In the ensuring years other classes of antihypertensive drug were developed and found wide acceptance in combination therapy, including loop diuretics (Lasix/furosemide, Hoechst Pharmaceuticals, 1963), beta blockers (ICI Pharmaceuticals, 1964) ACE inhibitors, and angiotensin receptor blockers. ACE inhibitors reduce the risk of new onset kidney disease [RR 0.71] and death [RR 0.84] in diabetic patients, irrespective of whether they have hypertension.
What do ACE inhibitors do?
A: reduce the risk of new onset kidney disease [RR 0.71] and death [RR 0.84] in diabetic patients

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Chopin's music remains very popular and is regularly performed, recorded and broadcast worldwide. The world's oldest monographic music competition, the International Chopin Piano Competition, founded in 1927, is held every five years in Warsaw. The Fryderyk Chopin Institute of Poland lists on its website over eighty societies world-wide devoted to the composer and his music. The Institute site also lists nearly 1,500 performances of Chopin works on YouTube as of January 2014.
Where is the International Chopin Piano Competition held?
A: Warsaw

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The Thomson Corporation management were struggling to run the business due to the 1979 Energy Crisis and union demands. Management were left with no choice but to find a buyer who was in a position to guarantee the survival of both titles, and also one who had the resources and was committed to funding the introduction of modern printing methods.
What kind of demands were causing ruin to The Times in 1979?
A: union demands

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In parliamentary systems, governments are generally required to have the confidence of the lower house of parliament (though a small minority of parliaments, by giving a right to block supply to upper houses, in effect make the cabinet responsible to both houses, though in reality upper houses, even when they have the power, rarely exercise it). Where they lose a vote of confidence, have a motion of no confidence passed against them, or where they lose supply, most constitutional systems require either:
What kind of referendum can the lower house of parliament take against the government?
A:
vote of confidence