Premise:
"As he carried her over the threshold, the house began to collapse and she fled, leaving him forever; his business subsequently failed and he became a broken man."
Hypothesis: If he didn't carry her over the threshold, she might have not left him forever.

it is not possible to tell

Premise:
" He can't do it."
Hypothesis: He wouldn't be able to do it in different circumstances.

it is not possible to tell

Premise:
"As unusual as Button's case is, it shares one common characteristic with nearly all the 30,000 suicides that occur each year in the United States--the victims are not in a rational state of mind."
Hypothesis: Suicide by amputation is uncommon, but further points out the fact that suicidal tendencies are not associated with clear thinking.
it is not possible to tell