In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.

Question: The increase in standard free energy of ATP hydrolysis depends, among others, on the following structural characteristic:
Options: <0> Its polar character. <1> Its amphipathic nature <2> Its stabilization by resonance. <3> Of the phosphoryl group number it contains. <4> Of the cation with which the soluble salt forms.
chemistry