Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).

Q: Abstract: A reverse hemolytic plaque assay for detecting casein release from individual mammary cells in culture was developed as a bioassay for PRL. Treatment with rat PRL caused dose-related increases in the percentage of mammary cells that released casein and the average size of casein plaques that formed. The assay exhibited exquisite sensitivity (156 fg rat PRL per assay slide) and could be used to evaluate the biopotency of PRL released from individual cells. By combining this "plaque bioassay" with a standard plaque assay for measuring the secretion of immunoreactive PRL, it was possible to compare the bio- and immuno-potencies of hormone released from the same pituitary cells. The results of three separate studies revealed major differences among PRL secretors in these potency estimates. Given the existence of PRL variants with different biological and immunological efficacies, these findings suggest that PRL cells differ from one another in the molecular form(s) of hormone released.
Which is the apt title for the abstract? option1: A novel bioassay for lactogenic activity: demonstration that prolactin cells differ from one another in bio- and immuno-potencies of secreted hormone. option2: Meningeal melanocytoma. Case report and review of the clinical and histological features.

A: A novel bioassay for lactogenic activity: demonstration that prolactin cells differ from one another in bio- and immuno-potencies of secreted hormone.
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Q: Abstract: Aneurysms of the extracranial vertebral artery are rare because of the protection afforded by the bony canal, and the literature contains only a few limited reports on this subject. In the view of its rarity, we present the case of a 20-year-old soldier with a traumatic aneurysm of the vertebral artery at the C-2 level. Because of occlusion of the ipsilateral carotid artery, reconstruction of the vertebral artery by autogenous vein graft was undertaken through a posterior approach; because of inadequate mobilization of the artery, continuity was preserved using aneurysmorrhaphy. The literature is reviewed, and the various treatments are discussed.
Which is the apt title for the abstract? option1: Traumatic aneurysm of the extracranial vertebral artery. option2: Hypervascular hepatic metastases: CT evaluation.

A: Traumatic aneurysm of the extracranial vertebral artery.
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Q: Abstract: Ball-and-socket ankle is a rare deformity associated with such pre-existing conditions as congenital shortening of the lower limb, coalition of tarsal bones, absent digital rays and aplasia or hypoplasia of the fibula. We have observed seven patients with this deformity for an average of six years from initial examination at 20 days to 3.5 years. Arthrography showed that the configuration of the ankle was apparently normal in patients under 10 months of age and that a ball-and-socket joint develops by four to five years of age, possibly in compensation for the loss of inversion and eversion caused by tarsal coalition. Ball-and-socket joint is therefore probably not congenital, but is an acquired deformity secondary to various pre-existing congenital conditions.
Which is the apt title for the abstract? option1: Genesis of the ball-and-socket ankle. option2: Effect of life in industrialized societies on hearing in natives of Easter Island.

A:
Genesis of the ball-and-socket ankle.
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