In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Let me give you an example: The severe acute respiratory syndrome (SARS) epidemic originating from China in 2002 was caused by a previously uncharacterized coronavirus that could be identified by specific RT-PCR amplification. Efforts to control future SARS outbreaks depend on the accurate and early identification of SARS-CoV infected patients. A real-time fluorogenic RT-PCR assay based on the 3 -noncoding region (3 -NCR) of SARS-CoV genome was developed as a quantitative SARS diagnostic tool. The ideal amplification efficiency of a sensitive SARS-CoV RT-PCR assay should yield an E value (PCR product concentration increase per amplification cycle) equal to 2.0. It was demonstrated that the 3 -NCR SARS-CoV based RT-PCR reactions could be formulated to reach excellent E values of 1.81, or 91% amplification efficacy. The SARS-CoV cDNA preparations derived from viral RNA extract and the cloned recombinant plasmid both exhibit the identical amplification characteristics, i.e. amplification efficacy using the same PCR formulation developed in this study. The viral genomic copy (or genomic equivalences, GE) per infectious unit (GE/pfu) of SARS-CoV used in this study was also established to be approximate 1200-1600:1. The assay's detection sensitivity could reach 0.005 pfu or 6-8 GE per assay. It was preliminarily demonstrated that the assay could efficiently detect SARS-CoV from clinical specimens of SARS probable and suspected patients identified in Taiwan. The 3 -NCR based SARS-CoV assay demonstrated 100% diagnostic specificity testing samples of patients with acute respiratory disease from a non-SARS epidemic region.
The answer to this example can be: Development and evaluation of an efficient 3 -noncoding region-based SARS coronavirus (SARS-CoV) RT-PCR assay for detection of SARS-CoV
Here is why: It's a correct title because the paragraph described the development of 3 -noncoding region of SARS-CoV genome and assay efficiently detecting SARS-CoV from clinical specimens.

OK. solve this:
Objective: To examine pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among severe acute respiratory syndrome (SARS) survivors. Methods: We evaluated survivors with confirmed SARS at the Prince of Wales Hospital, Hong Kong, at 3, 6, and 12 months after symptom onset. Our assessment included: lung volume (total lung capacity [TLC], vital capacity, residual volume, functional residual capacity), spirometry (FVC, FEV 1 ), diffusing capacity of the lung for carbon monoxide (DLCO), inspiratory and expiratory respiratory muscle strength, 6-min walk distance (6MWD), chest radiographs (CXRs), and HRQoL by Medical Outcomes Study 36-Item Short-Form General Health Survey questionnaire. Results: Ninety-seven patients completed the serial assessments. There were 39 male and 58 female patients, and 63 patients (70%) were health-care workers (mean age, 36.9 years [SD, 9.5 years]; body mass index, 23.7 kg/m 2 [SD, 4.0 kg/m 2 ]). At 1 year, 27 patients (27.8%) had abnormal CXR findings. Four patients (4.1%), 5 patients (5.2%), and 23 patients (23.7%) had FVC, TLC, and DLCO values < 80% of predicted values, respectively. The 6MWD at 12 months was 511.0 m (SD, 89.8 m), which was higher than at 3 months (mean difference, 47.0 m; 95% confidence interval [CI], 31.8 to 62.1 m; p < 0.01) but not different from 6 months (mean difference, 9.7 m; 95% CI, 4.4 to 23.8 m; p 0.18). The 6MWD was lower than that for normal control subjects of the same age groups, and there was impairment of HRQoL at 12 months. Patients who required ICU admission (n 31) showed higher CXR scores (1.6 [SD, 3.1]; vs 0.4 [SD, 1.1]; p 0.04) and lower percentage of predicted FVC, TLC, and DLCO than those who did not, but there were no differences in 6MWD and health status. Conclusion: Significant impairment in DLCO was noted in 23.7% of survivors 1 year after illness onset. Exercise capacity and health status of SARS survivors were remarkably lower than those of a normal population. (CHEST 2005; 128:2247-2261) Key words: severe acute respiratory syndrome; lung function; functional capacity; quality of life Abbreviations: ANOVA analysis of variance; BMI body mass index; BOOP bronchiolitis obliterans organizing pneumonia; BP bodily pain; CI confidence interval; CPET cardiopulmonary exercise testing; CRP C-reactive protein; CXR chest radiograph; Dlco diffusing capacity of the lung for carbon dioxide; FEF 25-75 forced expiratory flow, midexpiratory phase; FRC functional residual capacity; GH general health; HCW health-care worker; HK Hong Kong; HRCT high-resolution CT; HRQoL health-related quality of life; IQR interquartile range; Kco diffusing capacity of the lung for carbon dioxide adjusted for alveolar volume; LDH lactate dehydrogenase; LOS length of stay; MH mental health; Pemax maximum static expiratory pressure; Pimax maximum static inspiratory pressure; PF physical functioning; RE role limitation due to emotional problems; RP role limitation due to physical problems; RV residual volume; SARS severe acute respiratory syndrome; SF social functioning; SF-36 Medical Outcomes Study 36-Item Short-Form General Health Survey; TLC total lung capacity; Va alveolar volume; VC vital capacity; VT vitality; 6MWD 6-min walk distance; 6MWT 6-min walk test T he emergence of severe acute respiratory syndrome (SARS) in Southern China in November 2002, followed by the global outbreak in 2003, caught the medical profession by surprise. 1-3 Studies on SARS-coronavirus viral loads have shown that peak viral levels were reached at the second week of illness when patients were receiving hospital care, and thus health-care workers (HCWs) were particularly prone to infection while caring for their patients. 4, 5 The morbidity of SARS is highlighted by the observation that even when there was only 10% of total lung field involved by consolidation, 50% of patients would require supplemental oxygen in order
Answer:
The 1-Year Impact of Severe Acute Respiratory Syndrome on Pulmonary Function, Exercise Capacity, and Quality of Life in a Cohort of Survivors* *From the Center for Emerging Infectious Diseases (Drs and Tam), and Diagnostic Radiology and Organ Imaging