In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
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Question: Question: Urine is hypoosmolar with respect to plasma in:
Options: <1> Bowman's capsule. <2> Proximal tubule <3> Medulla area of the loop of Henle. <4> Initial zone of the distal tubule. <5> Collecting tubule in the presence of ADH.

Answer: 4

Question: Question: In the health report of Mrs. P. T. of 83 years of age, it is reported that she has a depressive picture. Regarding depression in the elderly has been described that:
Options: <1> It is uncommon for them to have somatic symptoms. <2> It is not characteristic that cognitive disorders appear. <3> The Yesavage scale is an instrument to establish a safe diagnosis of depression. <4> There is unanimity in stating that it has specific manifestations in the elderly. <5> There may be pictures of pseudodementia, with symptoms of dementia but caused by depressive states.

Answer: 5

Question: Question: The RISC complex (RNA-induced silencing complex) of RNA silencing based on interference RNA:
Options: <1> It degrades the guide strand of the small interfering RNA molecules (siRNA). <2> It recognizes defective proteins and promotes their degradation. <3> It has a structure similar to the ribosome, formed by numerous RNAs and proteins. <4> It is formed, among others, by the Dicer protein, a type III ribonuclease. <5> It is part of both the interference mechanism of the siRNA and the microRNA.

Answer:
5