Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Paragraph: The National Park Service and the U.S. Public Health Service told the San Francisco Chronicle they launched an investigation after employees and visitors reported the problems this month. Federal officials said they haven't identified the illness or the origin of the outbreak. Park officials said those who had gotten sick are getting better or already recovered. Federal officials were working with Aramark, the concessionaire that operates Yosemite's restaurants, snack shops and hotels, to clean up and disinfect food service facilities in the park, including the famous Ahwahnee Hotel, Yosemite spokesman Scott Gediman said. "The park is reminding all employees and visitors to wash their hands frequently and stay home if they experience any symptoms of a gastrointestinal illness," Gediman said in a statement. A message seeking comment from a spokesman for Aramark has not been returned. Aramark received numerous complaints from visitors about poor food quality, shuttle service and other services since it began managing Yosemite's concessions four years ago. The Ahwahnee Hotel lost its prestigious four-diamond rating by AAA, a distinction the luxury hotel held since 1991, and is now listed as a three-diamond hotel. Visitors to the hotel at the foot of the iconic Half Dome have included Queen Elizabeth II and U.S. presidents. Claim: Stomach illness outbreak at Yosemite prompts major clean-up.
Federal health officials are inspecting Yosemite National Park's food service areas after at least a dozen people have fallen ill with stomach issues.

Paragraph: The trial results on patients with a gene anomaly known as NTRK fusion, which occurs in less than 1 percent across a range of tumor types, were presented at the annual congress of the European Society for Medical Oncology (ESMO) in Munich on Sunday. Germany's Bayer and U.S. partner Loxo, in turn, released data for their rival compound larotrectinib, which slightly improved on previous high-efficacy readings in an enlarged trial. Traditionally, oncologists have made treatment decisions based on where in the body a tumor started, increasingly helped by the growing knowledge of cancer's complex genetic drivers. Under the tumor-agnostic approach, also known as pan-tumor, drugmakers skip the organ-of-origin perspective and regroup patients based only on signature genetic mutations, but success in real life will depend on the fast spread of comprehensive gene-sequencing tools for tissue samples. Individually, the mutations are so rare that cancer units are seen as unlikely to run dedicated tests for each. Roche's Foundation Medicine supplies the comprehensive kits, competing with Thermo Fisher Scientific and Caris Life Sciences. "It's one of the reasons we acquired Foundation Medicine, to make this comprehensive genomic profiling routine and upfront in the course of the disease," said Daniel O'Day, the head of Roche's Pharmaceuticals division. Loxo's larotrectinib pill, co-developed with Bayer, was last year shown to shrink tumors in 75 percent of patients with the NTRK fusion gene anomaly, occurring in the lung, pancreas, or more than a dozen other organs. On Sunday, the response rate to larotrectinib within an enlarged group of 122 trial participants - up from 55 initially and now spanning 24 tumor types - was shown to be 81 percent. Roche said the readings from the two NTRK fusion trials were not comparable because they are made up of different patient types. Loxo's study, for instance, included some cancers in children, while Roche plans to investigate those separately. The Roche compound is designed to tackle several oncogenic mutations and last month, it unveiled data here on entrectinib pushing back tumors in 77 percent of lung cancer patients with a mutation called ROS1. Merck & Co's Keytruda in May last year became the first drug to win approval for pan-tumor use, though that remains a relatively small market for the mega-selling drug. Bayer and Loxo are testing a second pan-tumor drug, LOXO-195. Roche Pharmaceutical's O'Day welcomed a wider field. "Both things have to happen: You need genomic profiling and you need enough targeted medicines to encourage physicians to make that diagnosis upfront very complete. This is the world we're entering," he said. Though response rates could encourage a race for more such drugs, the need for suitable gene mutations or fusions will be a tall order, said oncologist Ulrik Lassen of Copenhagen's Rigshospitalet, who co-authored the larotrectinib study. "You need to screen a lot of patients to find the needle in the haystack and the method is complicated, costly and time-consuming. When we get better at using these technologies, we can find more oncogenic fusions and companies will be smart enough to find the agents that target them." Roche acquired entrectinib as part of its takeover deal with U.S. cancer drug specialist Ignyta Inc for $1.7 billion, agreed in December last year. Immuno-oncology remains another major business area for Roche, which also released positive results on using its Tecentriq drug in a group of breast cancer patients with a particularly poor prognosis. Claim: Roche takes on Loxo, Bayer in gene-defined cancer class.
Roche's entrectinib cancer pill was shown to shrink tumors in 57 percent of patients within a group that can only be identified via genetic profiling, as the Swiss drugmaker challenges an alliance of Bayer and Loxo Oncology in a new targeted treatment area.

Paragraph: In a letter, 44 firms, including Allianz, Handelsbanken, Aberdeen Investment and Aegon NV, said a law would give investors more confidence to make long-term decisions on environmentally responsible projects. The move showcases investors' increased focus on climate change, both as a risk and an opportunity. Quoting the "catastrophic" impact of ignoring the issue, the group said uncontrolled climate change could cost the global economy $23 trillion. "Conversely, greater action on climate change could deliver $26 trillion in global economic benefit by 2030," the letter, released Friday, said. Most of the 28 EU member states have signed up to an EU-wide pledge to be climate neutral by 2050 but Poland, the Czech Republic and Hungary are dragging their feet. A law would force all member states to achieve climate neutrality by 2050. Ursula von der Leyen, the new president of the European Union's executive Commission, has made combating climate change one of her top priorities. She has unveiled a "Sustainable Europe Investment Plan" which would support one trillion euros in investment over the next decade, and pledged to turn the 2050 target, something that will require a near-complete phasing-out of fossil fuels, into the "first European Climate Law." Claim: Omega-3 margarines fail to help in heart study
European investors representing over six trillion euros in assets are calling on European Union governments to speed up efforts to enshrine the EU's 2050 climate neutrality goal in law.