Input: Kathmandu
Kathmandu is home to Nepali cinema and theaters. The city contains several theaters, including the National Dance Theatre in Kanti Path, the Ganga Theatre, the Himalayan Theatre and the Aarohan Theater Group founded in 1982. The M. Art Theater is based in the city. The Gurukul School of Theatre organizes the Kathmandu International Theater Festival, attracting artists from all over the world. A mini theater is also located at the Hanumandhoka Durbar Square, established by the Durbar Conservation and Promotion Committee.

Who constructed the theater in Hanumandhoka Durbar Square?
Output: Durbar Conservation and Promotion Committee

Input: Lancashire
Lancashire had a lively culture of choral and classical music, with very large numbers of local church choirs from the 17th century, leading to the foundation of local choral societies from the mid-18th century, often particularly focused on performances of the music of Handel and his contemporaries. It also played a major part in the development of brass bands which emerged in the county, particularly in the textile and coalfield areas, in the 19th century. The first open competition for brass bands was held at Manchester in 1853, and continued annually until the 1980s. The vibrant brass band culture of the area made an important contribution to the foundation and staffing of the Halle Orchestra from 1857, the oldest extant professional orchestra in the United Kingdom. The same local musical tradition produced eminent figures such as Sir William Walton (190288), son of an Oldham choirmaster and music teacher, Sir Thomas Beecham (18791961), born in St. Helens, who began his career by conducting local orchestras and Alan Rawsthorne (190571) born in Haslingden. The conductor David Atherton, co-founder of the London Sinfonietta, was born in Blackpool in 1944. Lancashire also produced more populist figures, such as early musical theatre composer Leslie Stuart (18631928), born in Southport, who began his musical career as organist of Salford Cathedral.

What year was the first open competition for brass bands held?
Output: 1853

Input: On the Origin of Species
In late September 1838, he started reading Thomas Malthus's An Essay on the Principle of Population with its statistical argument that human populations, if unrestrained, breed beyond their means and struggle to survive. Darwin related this to the struggle for existence among wildlife and botanist de Candolle's "warring of the species" in plants; he immediately envisioned "a force like a hundred thousand wedges" pushing well-adapted variations into "gaps in the economy of nature", so that the survivors would pass on their form and abilities, and unfavourable variations would be destroyed. By December 1838, he had noted a similarity between the act of breeders selecting traits and a Malthusian Nature selecting among variants thrown up by "chance" so that "every part of newly acquired structure is fully practical and perfected".

Which book did Darwin begin reading in 1838?
Output: An Essay on the Principle of Population

Input: Infection
In the absence of suitable plate culture techniques, some microbes require culture within live animals. Bacteria such as Mycobacterium leprae and Treponema pallidum can be grown in animals, although serological and microscopic techniques make the use of live animals unnecessary. Viruses are also usually identified using alternatives to growth in culture or animals. Some viruses may be grown in embryonated eggs. Another useful identification method is Xenodiagnosis, or the use of a vector to support the growth of an infectious agent. Chagas disease is the most significant example, because it is difficult to directly demonstrate the presence of the causative agent, Trypanosoma cruzi in a patient, which therefore makes it difficult to definitively make a diagnosis. In this case, xenodiagnosis involves the use of the vector of the Chagas agent T. cruzi, an uninfected triatomine bug, which takes a blood meal from a person suspected of having been infected. The bug is later inspected for growth of T. cruzi within its gut.

What is Xenodiagnosis?
Output:
use of a vector to support the growth of an infectious agent