Overall amniocentesis is a safe procedure with the risk of fetal loss at generally less than 1 According to the American College of Obstetricians and Gynecologists Practice Bulletin there is a procedurerelated rate of fetal loss ranging from 1300 to 1500 procedures

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Overall, amniocentesis is a safe procedure with the risk of fetal loss at generally less than 1%. According to the American College of Obstetricians and Gynecologists Practice Bulletin, there is a procedure-related rate of fetal loss ranging from 1/300 to 1/500 procedures.