Detailed Instructions: In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.
Q: Question: The development of generic drugs is based on the evaluation of the bioequivalence of the generic compared to a reference product already marketed. This concept refers to:
Options: <0> The evaluation of equivalence in clinical efficacy trials. <1> The assessment of similarity in clinical trials of tolerance. <2> The equivalence in the distribution process of a drug and, therefore, to the verification that it has the same concentrations in the place of action. <3> The evaluation of pharmacokinetic equivalence. <4> The verification of a similar effect of the factors that influence the bioavailability of a drug.
A:
medicine