Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
Topographic maps represent the locations of geographical features, such as hills and valleys. Topographic maps use contour lines to show different elevations. A contour line is a line of equal elevation. If you walk along a contour line you will not go uphill or downhill. Topographic maps are also called contour maps. The rules of topographic maps are: Each line connects all points of a specific elevation. Contour lines never cross since a single point can only have one elevation. Every fifth contour line is bolded and labeled. Adjacent contour lines are separated by a constant difference in elevation (such as 20 ft or 100 ft). The difference in elevation is the contour interval, which is indicated in the map legend. Scales indicate horizontal distance and are also found on the map legend. Old Faithful erupting, Yellowstone Na- tional Park. While the Figure 1.1 isnt exactly the same view as the map at the top of this concept, it is easy to see the main features. Hills, forests, development, and trees are all seen around Old Faithful. A bathymetric map is like a topographic map with the contour lines representing depth below sea level, rather than height above. Numbers are low near sea level and become higher with depth. Kilauea is the youngest volcano found above sea level in Hawaii. On the flank of Kilauea is an even younger volcano called Loihi. The bathymetric map pictured in the Figure 1.2 shows the form of Loihi. Loihi volcano growing on the flank of Kilauea volcano in Hawaii. Black lines in the inset show the land surface above sea level and blue lines show the topography below sea level. A geologic map of the region around Old Faithful, Yellowstone National Park. A geologic map shows the geological features of a region (see Figure 1.3 for an example). Rock units are color- coded and identified in a key. Faults and folds are also shown on geologic maps. The geology is superimposed on a topographic map to give a more complete view of the geology of the region. Click image to the left or use the URL below. URL:

Ex Output:
this type of map shows rock units and features like faults and folds.

Ex Input:
Today, the Eiffel Tower, which serves an important role in television and radio broadcasts, is considered an architectural wonder. It attracts more visitors than any other paid tourist attraction in the world. The Eiffel Tower was designed by the French engineer and bridge builder Alexandre Gustave Eiffel for the Paris Exposition of 1889. The tower is 300 m high and consists of an open iron framework making it the highest manmade structure in the world at the time. It was almost not built. After being awarded the contract to build the tower, Eiffel discovered that the Exposition Committee would only provide about a quarter of the money needed to construct it. Eiffel himself would have to finance the balance. He thought of a deal that would make him a very rich man. He agreed to independently find the people to fund his tower but he wanted to be the only one to control of the tower and he wanted the profits for twenty years. They agreed. To everyone's surprise, including Eiffel, the tower was paid off in the first year. The deal that Eiffel came up with was probably what saved the tower from destruction. A Committee of Three Hundred was formed and they demanded an end to its building. Many members of the committee said, "They have only put up the framework of this monument, It has no skin." Many sculptors and architects protested , in the name of threatened French art and history, about the useless Eiffel Tower, in the heart of their capital. It is built of iron, which is an inferior material, and a single beam of it is unable to support large stresses. That is why the tower appears over-engineered by today's standards. Though, from this very weakness, its simple beauty can be found. If you look at the tower, the structure of it sort of copies the biological cellular structure of a plant.

Ex Output:
What was the Eiffel Tower originally designed for?

Ex Input:
Facioscapulohumeral Disease (FSHD) is a dominantly inherited progressive myopathy associated with aberrant production of the transcription factor, Double Homeobox Protein 4 (DUX4). The expression of DUX4 depends on an open chromatin conformation of the D4Z4 macrosatellite array and a specific haplotype on chromosome 4. Even when these requirements are met, DUX4 transcripts and protein are only detectable in a subset of cells indicating that additional constraints govern DUX4 production. Since the direction of transcription, along with the production of non-coding antisense transcripts is an important regulatory feature of other macrosatellite repeats, we developed constructs that contain the non-coding region of a single D4Z4 unit flanked by genes that report transcriptional activity in the sense and antisense directions. We found that D4Z4 contains two promoters that initiate sense and antisense transcription within the array, and that antisense transcription predominates. Transcriptional start sites for the antisense transcripts, as well as D4Z4 regions that regulate the balance of sense and antisense transcripts were identified. We show that the choice of transcriptional direction is reversible but not mutually exclusive, since sense and antisense reporter activity was often present in the same cell and simultaneously upregulated during myotube formation. Similarly, levels of endogenous sense and antisense D4Z4 transcripts were upregulated in FSHD myotubes. These studies offer insight into the autonomous distribution of muscle weakness that is characteristic of FSHD.

Ex Output:
Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?