In El Chapo, the 2017 Netflix and Univision TV series about the life of Joaquin "El Chapo" Guzman, Fuentes is portrayed by Rodrigo Abed. El Senor de los Cielos (2013), El Senor de los Cielos 2 (2014), El Senor de los Cielos 3 (2015), and El Senor de los Cielos 4, aired as part of Telemundo's nighttime programming, stars the Mexican actor Rafael Amaya as Aurelio Casillas (a fictionalized version of Amado Carrillo Fuentes). In the Netflix Original series Narcos, Fuentes is portrayed by Jose Maria Yazpik.

Who is el senor de los cielos based on? Okie... think carefully first, then make a decision:
The relevant information to answer the above question is: El Senor de los Cielos (2013), El Senor de los Cielos 2 (2014), El Senor de los Cielos 3 (2015), and El Senor de los Cielos 4, aired as part of Telemundo's nighttime programming, stars the Mexican actor Rafael Amaya as Aurelio Casillas (a fictionalized version of Amado Carrillo Fuentes). So, the answer is Amado Carrillo Fuentes.