Given the task definition and input, reply with output. In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Paragraph: The epidemiology of deaths due to vaccine-preventable diseases has been significantly and positively altered through the use of vaccines. Despite this, significant challenges remain in vaccine development and use in the third millennium. Both new (Ebola, Chikungunya, West Nile) and re-emerging diseases (measles, mumps, influenza) require the development of new or nextgeneration vaccines. The global aging of the population, and accumulating numbers of immunocompromised persons, will require new vaccine and adjuvant development to protect large segments of the population. After vaccine development, significant challenges remain globally in the cost and efficient use and acceptance of vaccines by the public. This article raises issues in these two areas and suggests a way forward that will benefit current and future generations. Description Massively parallel sequencing platforms that generate millions of bases of sequence reads in a relatively short timeframe. These platforms have a wide variety of applications including, but not limited to: whole genome sequencing, transcriptome profiling, or identification of genome-wide patterns of miRNA patterns or DNA methylation. Mass spectrometry techniques for the unbiased, semi-quantitative characterization of the entire protein content of a sample. Mass cytometry. Single cell analysis platform combining mass spectrometry with flow cytometry. Antibodies are tagged with heavy metal ions and used to stain cell populations of interest. Spectral overlap limits flow cytometry to ~20 markers. CyTOF has increased signal resolution and potentially offers 10X as many parameters. An approach to understanding variations in immune response to vaccines that utilizes high-dimensional technologies to fully characterize, at an omics level, the perturbations elicited by vaccination. This rich dataset is then analyzed using bioinformatic tools and computational modeling to create a predictive model of immune responses that can be tested and improved through iterative experimental cycles. A set of methods for capturing the transcriptome of individual cells. Methods include: STRT, SMART-Seq, Quartz-Seq, and CEL-Seq Epitope Prediction Algorithms A set of computational tools that use binding motif databases, artificial neural networks, hidden Markov models, support vector machines or other methods to predict MHC-binding peptides in protein sequences. Examples include: SYFPEITHI, BIMAS, PREDEP, RANKPEP Curr Opin Virol. Author manuscript; available in PMC 2017 April 01.
Title: Vaccinology in the third millennium: scientific and social challenges HHS Public Access Author manuscript
False