metabolic anemia in dogs occurs as the result of any underlying disease related to the kidney, liver, or spleen by which the shape of red blood cells (rbcs) is changed. normally, red blood cells (rbcs) in dogs are of biconcave discoid shape, but in metabolic anemia, this shape is lost and they become abnormally elongated and blunt, with finger-like projections called spicules coming out of the surface of the rbcs. these abnormalities render rbcs non-functional, and left untreated, can lead to anemia in affected dogs.
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Metabolic anemia in dogs occurs as the result of any underlying disease related to the kidney, liver, or spleen by which the shape of red blood cells (RBCs) is changed. Normally, red blood cells (RBCs) in dogs are of biconcave discoid shape, but in metabolic anemia, this shape is lost and they become abnormally elongated and blunt, with finger-like projections called spicules coming out of the surface of the RBCs. These abnormalities render RBCs non-functional, and left untreated, can lead to anemia in affected dogs.