instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Humans use six times as much water today as they did 100 years ago. People living in developed countries use a far greater proportion of the worlds water than people in less developed countries. What do people use all of that water for? Besides drinking and washing, people need water for agriculture, industry, household uses, and recreation (Figure Water use can be consumptive or non-consumptive, depending on whether the water is lost to the ecosystem. Non-consumptive water use includes water that can be recycled and reused. For example, the water that goes down the drain and enters the sewer system is purified and then redistributed for reuse. By recycling water, the overall water consumption is reduced. Consumptive water use takes the water out of the ecosystem. Can you name some examples of consumptive water use? Some of the worlds farmers still farm without irrigation by choosing crops that match the amount of rain that falls in their area. But some years are wet and others are dry. For farmers to avoid years in which they produce little or no food, many of the worlds crops are produced using irrigation. Water used for home, industrial, and agricultural purposes in different regions. Globally more than two-thirds of water is for agriculture. Three popular irrigation methods are: Overhead sprinklers. Trench irrigation: canals carry water from a water source to the fields. Flood irrigation: fields are flooded with water. All of these methods waste water. Between 15% and 36% percent of the water never reaches the crops because it evaporates or leaves the fields as runoff. Water that runs off a field often takes valuable soil with it. A much more efficient way to water crops is drip irrigation (Figure 1.2). With drip irrigation, pipes and tubes deliver small amounts of water directly to the soil at the roots of each plant or tree. The water is not sprayed into the air or over the ground, so nearly all of it goes directly into the soil and plant roots. Why do farmers use wasteful irrigation methods when water-efficient methods are available? Many farmers and farming corporations have not switched to more efficient irrigation methods for two reasons: 1. Drip irrigation and other more efficient irrigation methods are more expensive than sprinklers, trenches, and flooding. 2. In the United States and some other countries, the government pays for much of the cost of the water that is used for agriculture. Because farmers do not pay the full cost of their water use, they do not have any financial incentive to use less water. What ideas can you come up with to encourage farmers to use more efficient irrigation systems? Aquaculture is a different type of agriculture. Aquaculture is farming to raise fish, shellfish, algae, or aquatic plants (Figure 1.3). As the supplies of fish from lakes, rivers, and the oceans dwindle, people are getting more fish from aquaculture. Raising fish increases our food resources and is especially valuable where protein sources are limited. Farmed fish are becoming increasingly common in grocery stores all over the world. Workers at a fish farm harvest fish they will sell to stores. Growing fish in a large scale requires that the fish stocks are healthy and protected from predators. The species raised must be hearty, inexpensive to feed, and able to reproduce in captivity. Wastes must be flushed out to keep animals healthy. Raising shellfish at farms can also be successful. For some species, aquaculture is very successful and environmental harm is minimal. But for other species, aqua- culture can cause problems. Natural landscapes, such as mangroves, which are rich ecosystems and also protect coastlines from storm damage, may be lost to fish farms (Figure 1.4). For fish farmers, keeping costs down may be a problem since coastal land may be expensive and labor costs may be high. Large predatory fish at the 4th or 5th trophic level must eat a lot, so feeding large numbers of these fish is expensive and environmentally costly. Farmed fish are genetically different from wild stocks, and if they escape into the wild they may cause problems for native fish. Because the organisms live so close together
answer:
water that can be recycled and reused is called ____________water use.

question:
Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety and analgesic efficacy of tanezumab, a humanized monoclonal antibody that binds and inhibits nerve growth factor. We randomly assigned 450 patients with osteoarthritis of the knee to receive tanezumab (administered at a dose of 10, 25, 50, 100, or 200 g per kilogram of body weight) or placebo on days 1 and 56. The primary efficacy measures were knee pain while walking and the patient's global assessment of response to therapy. We also assessed pain, stiffness, and physical function using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); the rate of response using the criteria of the Outcome Measures for Rheumatology Committee and Osteoarthritis Research Society International Standing Committee for Clinical Trials Response Criteria Initiative (OMERACT-OARSI); and safety. When averaged over weeks 1 through 16, the mean reductions from baseline in knee pain while walking ranged from 45 to 62% with various doses of tanezumab, as compared with 22% with placebo (P<0.001). Tanezumab, as compared with placebo, was also associated with significantly greater improvements in the response to therapy as assessed with the use of the patients' global assessment measure (mean increases in score of 29 to 47% with various doses of tanezumab, as compared with 19% with placebo; P0.001). The rate of response according to the OMERACT-OARSI criteria ranged from 74 to 93% with tanezumab treatment, as compared with 44% with placebo (P<0.001). The rates of adverse events were 68% and 55% in the tanezumab and placebo groups, respectively. The most common adverse events among tanezumab-treated patients were headache (9% of the patients), upper respiratory tract infection (7%), and paresthesia (7%). In this proof-of-concept study, treatment with tanezumab was associated with a reduction in joint pain and improvement in function, with mild and moderate adverse events, among patients with moderate-to-severe osteoarthritis of the knee. (Funded by Rinat Neuroscience; ClinicalTrials.gov number, NCT00394563.).
answer:
What is the target of tanezumab?

question:
Later he would travel to Basra in Iraq to study under Hasan al-Basri (one of the Tabi''in). In Basra he began to develop the ideologies that would lead to the Mutazilite school. These stemmed from conflicts that many scholars had in resolving theology and politics. His main contribution to the Mutazilite school was in planting the seeds for the formation of its doctrine. Wasil ibn Ata died in 748 in the Arabian Peninsula. He married the sister of Amr ibn Ubayd.
answer:
What is Wasil ibn Ata's place of employment?