Washington (CNN) -- The U.S. Food and Drug Administration announced Wednesday that laboratory tests on popular smoking devices known as electronic cigarettes have found they contain carcinogens and other toxic chemicals dangerous to humans. E-cigarettes are battery-operated and contain cartridges filled with nicotine and other chemicals. Known as "e-cigarettes," the devices are battery-operated and contain cartridges filled with nicotine and other chemicals, spiced with flavors such as chocolate, cola or bubble gum. While manufacturers tout e-cigarettes as a "healthy way" to smoke, federal health officials say the devices turn nicotine, which is highly addictive, and other chemicals into a vapor that is inhaled by the user. "The FDA is concerned about the safety of these products and how they are marketed to the public," said Dr. Margaret A. Hamburg, commissioner of the FDA. CNN contacted Florida-based Smoking Everywhere, one of the largest manufacturers of e-cigarettes, after the FDA announcement, and a spokeswoman said the company had no comment. Because e-cigarettes have not been submitted to the FDA for evaluation or approval, the agency had no way of knowing the levels of nicotine or the amounts or kinds of other chemicals that the various brands of these products deliver to the user. That is why the FDA began to test them. The FDA's Division of Pharmaceutical Analysis analyzed the ingredients in a small sample of cartridges from two leading brands of e-cigarettes. In releasing its information, the FDA did not identify the two companies, but said in one sample, diethylene glycol -- a chemical used in antifreeze that is toxic to humans -- was detected. Other samples detected carcinogens that are dangerous to those who smoke them, the FDA said. The FDA has been examining and seizing shipments of non-U.S.-made e-cigarettes at the U.S. border since summer 2008. To date, 50 shipments have been stopped. The products examined thus far meet the definition of a combination drug-device product under the Federal Food, Drug, and Cosmetic Act. "We know very little about these devices, said Dr. Jonathan Samet, director of the Institute for Global Health at the University of Southern California, "but to say they are healthy -- that's highly doubtful."
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Answer: What might be two characteristics that would appeal to smokers who wish to quit?

The CIA's senior management saw problems with the armed Predator as well, problems that Clarke and even Black and Allen were inclined to minimize. One (which also applied to reconnaissance flights) was money. A Predator cost about $3 million. If the CIA flew Predators for its own reconnaissance or covert action purposes, it might be able to borrow them from the Air Force, but it was not clear that the Air Force would bear the cost if a vehicle went down. Deputy Secretary of Defense Wolfowitz took the position that the CIA should have to pay for it; the CIA disagreed. Second, Tenet in particular questioned whether he, as Director of Central Intelligence, should operate an armed Predator." This was new ground,"he told us. Tenet ticked off key questions: What is the chain of command? Who takes the shot? Are America's leaders comfortable with the CIA doing this, going outside of normal military command and control? Charlie Allen told us that when these questions were discussed at the CIA, he and the Agency's executive director, A. B." Buzzy" Krongard, had said that either one of them would be happy to pull the trigger, but Tenet was appalled, telling them that they had no authority to do it, nor did he. Third, the Hellfire warhead carried by the Predator needed work. It had been built to hit tanks, not people. It needed to be designed to explode in a different way, and even then had to be targeted with extreme precision. In the configuration planned by the Air Force through mid-2001, the Predator's missile would not be able to hit a moving vehicle. White House officials had seen the Predator video of the "man in white." On July 11, Hadley tried to hurry along preparation of the armed system. He directed McLaughlin, Wolfowitz, and Joint Chiefs Vice Chairman Richard Myers to deploy Predators capable of being armed no later than September 1.
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Answer: Deputy Secretary of Defense Wolfowitz believed that the CIA should have to pay 3 million for what?

Here the omnibus came up, and I rode back to Manchester. The whole conversation took up very little more time than it will take to read it; but I thought it worth recording, as characteristic of the people now suffering in Lancashire from no fault of their own. I know the people well. The greatest number of them would starve themselves to that degree that they would not be of much more physical use in this world, before they would condescend to beg. But starving to death is hard work. What will winter bring to them when severe weather begins to tell upon constitutions lowered in tone by a starvation diet--a diet so different to what they have been used to when in work? What will the 1s. 6d. a-head weekly do for them in that hard time? If something more than this is not done for them, when more food, clothing, and fire are necessary to everybody, calamities may arise which will cost England a hundred times more than a sufficient relief--a relief worthy of those who are suffering, and of the nation they belong to--would have cost. In the meantime the cold wings of winter already begin to overshadow the land; and every day lost involves the lives, or the future usefulness, of thousands of our best population.
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Answer: Why were the people of Lancashire suffering?

The Dutch Take Over: Intent on capturing a piece of the Portuguese trade in pepper and other spices, the Java-based Dutch Ailied with the Malays in 1633 to blockade Melaka. The trade blockade was to last eight years, and ended in a seven-month siege. The Portuguese surrendered in 1641, wracked by malaria and dysentery and denied their usual reinforcements from Goa. By then, the city had become a stagnant backwater. Unlike the Portuguese, the Dutch decided to do business with the Malays of Johor, who controlled the southern half of the peninsula together with Singapore and the neighboring Riau islands. A trade treaty gave the Dutch command of the spice trade but reserved Johor's rights in tin exports from Perak, Selangor, and Klang. Without ever retrieving the supremacy of the old Melaka sultanate, Johor had become the strongest Asian power in the region. For the Dutch, Johor provided a buffer against other Europeans. Meanwhile, fresh blood came in with the migration into the southern interior of hardy Minangkabau farmers from Sumatra, while tough Bugis warriors from the east Indonesian Celebes (Sulawesi) roved the length and breadth of the peninsula. The Minangkabau custom of freely electing their leaders provided the model for rulership elections in modern federal Malaysia. Their confederation of States became today's Negeri Sembilan ("Nine States"), with Seremban as its capital. The name Minangkabau itself means roughly "buffalo horns" and is reflected in the distinctive upward curving roof in museums and government offices built in the traditional Minangkabau style. The Bugis were energetic merchants and great sailors. With the Dutch concentrating once more on Java and the Moluccas in the 18th century, the Bugis took advantage of the vacuum by raiding Perak and Kedah, imposing their chieftains in Selangor and becoming the power behind the throne in Johor. The Bugis in Johor's administration provided much of the spirit in that State's independent stand in the 19th and 20th centuries. Throughout this period, the east coast states enjoyed a relatively tranquil prosperity, Terengganu notably thriving from its textile industry and trading in pepper and gold with the Thais, Cambodians, and Chinese. The British, under the private auspices of the East India Company (EIC), were beginning to poke their noses into North Borneo.
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Answer:
Who's confederation of States became today's Negeri Sembilan?