Question: Adaptation of the endosymbiont to the host's lifestyle leads to many changes in the endosymbiontthe foremost being drastic reduction in its genome size. This is due to many genes being lost during the process of metabolism, and DNA repair and recombination. While important genes participating in the DNA to RNA transcription, protein translation and DNA/RNA replication are retained. That is, a decrease in genome size is due to loss of protein coding genes and not due to lessening of inter-genic regions or open reading frame (ORF) size. Thus, species that are naturally evolving and contain reduced sizes of genes can be accounted for an increased number of noticeable differences between them, thereby leading to changes in their evolutionary rates. As the endosymbiotic bacteria related with these insects are passed on to the offspring strictly via vertical genetic transmission, intracellular bacteria goes through many hurdles during the process, resulting in the decrease in effective population sizes when compared to the free living bacteria. This incapability of the endosymbiotic bacteria to reinstate its wild type phenotype via a recombination process is called as Muller's ratchet phenomenon. Muller's ratchet phenomenon together with less effective population sizes has led to an accretion of deleterious mutations in the non-essential genes of the intracellular bacteria. This could have been due to lack of selection mechanisms prevailing in the rich environment of the host.
Is there an answer to this question: What is the term that describes the way the endosymbiont can't go back to its original phenotype?

Answer: Muller's ratchet phenomenon

Question: Many major events caused Europe to change around the start of the 16th century, starting with the Fall of Constantinople in 1453, the fall of Muslim Spain and the discovery of the Americas in 1492, and Martin Luther's Protestant Reformation in 1517. In England the modern period is often dated to the start of the Tudor period with the victory of Henry VII over Richard III at the Battle of Bosworth in 1485. Early modern European history is usually seen to span from the start of the 15th century, through the Age of Reason and the Age of Enlightenment in the 17th and 18th centuries, until the beginning of the Industrial Revolution in the late 18th century.
Is there an answer to this question: When is the modern period dated in England?

Answer: Battle of Bosworth in 1485

Question: The strength of beers has climbed during the later years of the 20th century. Vetter 33, a 10.5% abv (33 degrees Plato, hence Vetter "33") doppelbock, was listed in the 1994 Guinness Book of World Records as the strongest beer at that time, though Samichlaus, by the Swiss brewer Hurlimann, had also been listed by the Guinness Book of World Records as the strongest at 14% abv. Since then, some brewers have used champagne yeasts to increase the alcohol content of their beers. Samuel Adams reached 20% abv with Millennium, and then surpassed that amount to 25.6% abv with Utopias. The strongest beer brewed in Britain was Baz's Super Brew by Parish Brewery, a 23% abv beer. In September 2011, the Scottish brewery BrewDog produced Ghost Deer, which, at 28%, they claim to be the world's strongest beer produced by fermentation alone.
Is there an answer to this question: What brewing company produced the beer Millennium?

Answer: Samuel Adams

Question: In March 2013, Microsoft also amended its certification requirements to allow tablets to use the 1024768 resolution as a minimum; this change is expected to allow the production of certified Windows 8 tablets in smaller form factorsa market which is currently dominated by Android-based tablets. Despite the reaction of industry experts, Microsoft reported that they had sold 100 million licenses in the first six months. This matched sales of Windows 7 over a similar period. This statistic includes shipments to channel warehouses which now need to be sold in order to make way for new shipments.
Is there an answer to this question: What changes did Microsoft make to its recertification requirements in March 2013?

Answer:
unanswerable