Question: You are given a new situation: Ben and Andy were two old friends. They both have high levels of cholesterol. Ben was prescribed cholesterol medication, while Andy didn't go to the doctor because he was careless. and a hint : Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. Please answer this question : Which friend took a drug that decreases blood levels of cholesterol?
Answer: Ben

Question: You are given a new situation: Two sister cities had different environments. Shanghai had big problems with air pollution while Berna took very good care of the surrounding environment and air quality. and a hint : Air pollution is harmful to human beings and other living things. About 22 million people die from air pollution each year. Breathing polluted air increases the risk of developing lung diseases such as asthma and lung cancer. Breathing bad air also increases the chances of dying from other diseases. Children are most likely to be affected by air pollution. That's because their lungs are still developing and growing. Children also take in more air for their size than adults do. Some air pollutants damage the environment as well as the health of living things. The type of damage depends on the pollutant. Air pollution can also harm the environment. Please answer this question : Which city had people at increased risk of dying from other diseases?
Answer: Shanghai

Question: You are given a new situation: The inuit tribe lived and hunted on the shores of the Arctic ocean., very close to the North pole. The weather there was very cold throughout the year. Their distant cousins the umpala tribe, lived thousands of miles away, on the shores of the Indian ocean, where the weather was humid and warm, in a tropical climate. and a hint : Located mostly in the Arctic north polar region in the middle of the Northern Hemisphere, the Arctic Ocean is almost completely surrounded by Eurasia and North America. It is partly covered by sea ice throughout the year and almost completely in winter. The Arctic Ocean's surface temperature and salinity vary seasonally as the ice cover melts and freezes; its salinity is the lowest on average of the five major oceans, due to low evaporation, heavy fresh water inflow from rivers and streams, and limited connection and outflow to surrounding oceanic waters with higher salinities. The summer shrinking of the ice has been quoted at 50%. The US National Snow and Ice Data Center (NSIDC) uses satellite data to provide a daily record of Arctic sea ice cover and the rate of melting compared to an average period and specific past years. Please answer this question : Which tribe lived near an ocean with higher salinity?
Answer:
umpala