In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Q: Question: Menopause is diagnosed by:
Options: <1> The presence of more frequent and abundant cycles of what corresponds to each woman's own pattern. <2> The absence of menstruation in twelve consecutive months. <3> Symptoms derived from estrogen deprivation, such as insomnia, hot flashes or dry skin and mucous membranes. <4> The spacing of the rules, which are becoming increasingly infrequent. <5> Hormonal analyzes, densitometry, mammography and cytology.
A:
2