Context and question: Serological methods are highly sensitive, specific and often extremely rapid tests used to identify microorganisms. These tests are based upon the ability of an antibody to bind specifically to an antigen. The antigen, usually a protein or carbohydrate made by an infectious agent, is bound by the antibody. This binding then sets off a chain of events that can be visibly obvious in various ways, dependent upon the test. For example, "Strep throat" is often diagnosed within minutes, and is based on the appearance of antigens made by the causative agent, S. pyogenes, that is retrieved from a patients throat with a cotton swab. Serological tests, if available, are usually the preferred route of identification, however the tests are costly to develop and the reagents used in the test often require refrigeration. Some serological methods are extremely costly, although when commonly used, such as with the "strep test", they can be inexpensive.
What does the binding set off that will result in something invisible in various ways?
Answer: unanswerable
Context and question: From January 1820, 2010 a national conference on Tibet and areas inhabited by Tibetans in Sichuan, Yunnan, Gansu and Qinghai was held in China and a substantial plan to improve development of the areas was announced. The conference was attended by General secretary Hu Jintao, Wu Bangguo, Wen Jiabao, Jia Qinglin, Li Changchun, Xi Jinping, Li Keqiang, He Guoqiang and Zhou Yongkang, all members of CPC Politburo Standing Committee signaling the commitment of senior Chinese leaders to development of Tibet and ethnic Tibetan areas. The plan calls for improvement of rural Tibetan income to national standards by 2020 and free education for all rural Tibetan children. China has invested 310 billion yuan (about 45.6 billion U.S. dollars) in Tibet since 2001. "Tibet's GDP was expected to reach 43.7 billion yuan in 2009, up 170 percent from that in 2000 and posting an annual growth of 12.3 percent over the past nine years."
How much, in US dollars, has China invested in Tibet since 2001?
Answer: about 45.6 billion
Context and question: As of the 201516 season, Premier League football has been played in 53 stadiums since the formation of the Premier League in 1992. The Hillsborough disaster in 1989 and the subsequent Taylor Report saw a recommendation that standing terraces should be abolished; as a result all stadiums in the Premier League are all-seater. Since the formation of the Premier League, football grounds in England have seen constant improvements to capacity and facilities, with some clubs moving to new-build stadiums. Nine stadiums that have seen Premier League football have now been demolished. The stadiums for the 201011 season show a large disparity in capacity: Old Trafford, the home of Manchester United has a capacity of 75,957 with Bloomfield Road, the home of Blackpool, having a capacity of 16,220. The combined total capacity of the Premier League in the 201011 season is 770,477 with an average capacity of 38,523.
Since which leagues creation have football grounds in Old Trafford seen steady improvements?
Answer:
unanswerable