Detailed Instructions: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Q: Question: Does remote ischemic preconditioning increase circulating or effector organ concentrations of proopiomelanocortin derivates?
Answer: We were not able to demonstrate a detectable increase in circulating POMC derivates by a standard rIPC stimulus, suggesting that rIPC effect is not mediated by local or detectable central release of these derivates.
A:
no