Problem: Drug discovery and development is very expensive; of all compounds investigated for use in humans only a small fraction are eventually approved in most nations by government appointed medical institutions or boards, who have to approve new drugs before they can be marketed in those countries. In 2010 18 NMEs (New Molecular Entities) were approved and three biologics by the FDA, or 21 in total, which is down from 26 in 2009 and 24 in 2008. On the other hand, there were only 18 approvals in total in 2007 and 22 back in 2006. Since 2001, the Center for Drug Evaluation and Research has averaged 22.9 approvals a year. This approval comes only after heavy investment in pre-clinical development and clinical trials, as well as a commitment to ongoing safety monitoring. Drugs which fail part-way through this process often incur large costs, while generating no revenue in return. If the cost of these failed drugs is taken into account, the cost of developing a successful new drug (new chemical entity, or NCE), has been estimated at about 1.3 billion USD(not including marketing expenses). Professors Light and Lexchin reported in 2012, however, that the rate of approval for new drugs has been a relatively stable average rate of 15 to 25 for decades.
How much does it cost to develop a new drug?
The answer is the following: about 1.3 billion

Problem: Following the success of Le Journal de Mickey (193444), dedicated comics magazines and full-colour comics albums became the primary outlet for comics in the mid-20th century. As in the US, at the time comics were seen as infantile and a threat to culture and literacy; commentators stated that "none bear up to the slightest serious analysis",[c] and that comics were "the sabotage of all art and all literature".[d]
What was seen as "infantile" in the United States?
The answer is the following: comics

Problem: The territory of modern-day Mexico was home to numerous indigenous civilizations prior to the arrival of the Spanish conquistadores: The Olmecs, who flourished from between 1200 BCE to about 400 BCE in the coastal regions of the Gulf of Mexico; the Zapotecs and the Mixtecs, who held sway in the mountains of Oaxaca and the Isthmus of Tehuantepec; the Maya in the Yucatan (and into neighbouring areas of contemporary Central America); the Purepecha in present-day Michoacan and surrounding areas, and the Aztecs/Mexica, who, from their central capital at Tenochtitlan, dominated much of the centre and south of the country (and the non-Aztec inhabitants of those areas) when Hernan Cortes first landed at Veracruz.
What was Mexico home to prior to the arrival of the Spaniards?
The answer is the following: indigenous civilizations

Problem: The release of a video-game Starpower: Beyonce was cancelled after Beyonce pulled out of a $100 million with GateFive who alleged the cancellation meant the sacking of 70 staff and millions of pounds lost in development. It was settled out of court by her lawyers in June 2013 who said that they had cancelled because GateFive had lost its financial backers. Beyonce also has had deals with American Express, Nintendo DS and L'Oreal since the age of 18.
What was the name of the video game that was cancelled for Beyonce?
The answer is the following:
Starpower: Beyonce