Given the task definition and input, reply with output. In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.

Question: For bi-component drugs it is true that:
Options: <0> The apparent volume of the distribution decreases with time from a maximum value to a value that becomes constant. <1> The apparent volume of distribution as a function of the area is greater than the apparent volume of distribution in the steady state of equilibrium. <2> The apparent volume of distribution is constant over time. <3> The so-called initial distribution volume is greater than the apparent volume of distribution in phase . <4> The apparent volume of distribution calculated by extrapolation is less than the apparent volume of distribution in the steady state equilibrium.
pharmacology