Input: Article: Genes are regulated so that they are expressed only when the product is needed, since expression draws on limited resources.:7 A cell regulates its gene expression depending on its external environment (e.g. available nutrients, temperature and other stresses), its internal environment (e.g. cell division cycle, metabolism, infection status), and its specific role if in a multicellular organism. Gene expression can be regulated at any step: from transcriptional initiation, to RNA processing, to post-translational modification of the protein. The regulation of lactose metabolism genes in E. coli (lac operon) was the first such mechanism to be described in 1961.

Now answer this question: What are examples of a cell's external environment?

Output: available nutrients, temperature and other stresses

Input: Article: Near the intersection of Craycroft and Ft. Lowell Roads are the remnants of the Historic Fort Lowell. This area has become one of Tucson's iconic neighborhoods. In 1891, the Fort was abandoned and much of the interior was stripped of their useful components and it quickly fell into ruin. In 1900, three of the officer buildings were purchased for use as a sanitarium. The sanitarium was then sold to Harvey Adkins in 1928. The Bolsius family Pete, Nan and Charles Bolsius purchased and renovated surviving adobe buildings of the Fort transforming them into spectacular artistic southwestern architectural examples. Their woodwork, plaster treatment and sense of proportion drew on their Dutch heritage and New Mexican experience. Other artists and academics throughout the middle of the 20th century, including: Win Ellis, Jack Maul, Madame Cheruy, Giorgio Belloli, Charels Bode, Veronica Hughart, Edward and Rosamond Spicer, Hazel Larson Archer and Ruth Brown, renovated adobes, built homes and lived in the area. The artist colony attracted writers and poets including beat generation Alan Harrington and Jack Kerouac whose visit is documented in his iconic book On the Road. This rural pocket in the middle of the city is listed on the National Register of Historic Places. Each year in February the neighborhood celebrates its history in the City Landmark it owns and restored the San Pedro Chapel.

Now answer this question: In what book did Jack Kerouac write about visiting Tucson?

Output: On the Road

Input: Article: The 25,000 cotton growers in the United States of America are heavily subsidized at the rate of $2 billion per year although China now provides the highest overall level of cotton sector support. The future of these subsidies is uncertain and has led to anticipatory expansion of cotton brokers' operations in Africa. Dunavant expanded in Africa by buying out local operations. This is only possible in former British colonies and Mozambique; former French colonies continue to maintain tight monopolies, inherited from their former colonialist masters, on cotton purchases at low fixed prices.

Now answer this question: What is the rate of subsidies of cotton growers in the US?

Output:
$2 billion per year