Given the task definition and input, reply with output. In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: A 45-year-old patient with a moderate smoking habit, no drinker, no other history of interest who has been diagnosed with squamous carcinoma of the oropharynx cT1N2b. It is pending decision of treatment in committee. What infectious agent would you be interested in confusing before proposing the treatment?
Options: <1> Helicobacter pylori. <2> Herpes Simplex virus type 2. <3> Human papilloma virus. <4> Epstein Barr virus. <5> Cytomegalovirus.
3