TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: The Jinfeng Gold Mine (Chinese: ) is an combined open pit and underground gold mining operation in the Guizhou province, China.

SOLUTION: The product of Jinfeng Gold Mine is what?

PROBLEM: The SET domain contains the catalytic center of lysine methyltransferases that target the N-terminal tails of histones and regulate chromatin function. Here we report the structure of the SET7/9 protein in the absence and presence of its cofactor product, S-adenosyl-L-homocysteine (AdoHcy). A knot within the SET domain helps form the methyltransferase active site, where AdoHcy binds and lysine methylation is likely to occur. A structure-guided comparison of sequences within the SET protein family suggests that the knot substructure and active site environment are conserved features of the SET domain.

SOLUTION: What is the characteristic domain of histone methyltransferases?

PROBLEM: Transmembrane protein 53, or TMEM53, is a protein that is encoded on chromosome 1 in humans.

SOLUTION:
Which chromosone can you find Transmembrane protein 53?