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You will apply Advantix to various locations along your dog's back. Having your dog in the standing position will help you apply Advantix more easily and accurately on his skin. If your dog tends to be a bit squirmy, you can have someone gently restrain your dog while you apply the Advantix. Use your fingers to part the fur until you can see the skin. Advantix needs to be applied to the skin for maximum effectiveness. The first location where you will apply the Advantix is at the start of your dog's back, right near the base of his neck. Small and medium dogs will need three Advantix applications along their backs. Large and extra-large dogs will need four Advantix applications along their backs. If your dog is extremely furry, it may be helpful to clip away a little bit of hair to make it easier to apply the Advantix. Gently place the tip of the tube on your dog's skin. Squeeze about 1/3 or 1/4 of the Advantix onto the skin, depending on how many applications your dog will need. You want to be careful not to apply too much Advantix to the skin; this could cause the product to get on your dog's hair and drip down his side. Not only will this waste the product, but it increases the likelihood that your dog may ingest the Advantix. Advantix should not be applied if the skin is wet or broken. Dry your dog's skin if it is wet. If the skin is broken, do not apply the Advantix and contact your veterinarian. It is not necessary to massage the product into the skin after applying it. Another reason not to massage the product into your dog's skin is that Advantix can be harmful to human skin. The remaining applications should be spaced at least a few inches apart down your dog's back. For large and extra-large dogs, the last dose should be near the top of the tail. For small and medium dogs, the last dose should be near the middle of the back. Avoid petting the dog for several hours after application, as you may wipe the product off the skin. It might be best to apply Advantix shortly before the dog goes to bed to minimize the chances of accidentally wiping it off.
Have your dog stand up. Part your dog's fur. Apply the Advantix.