Given a scientific passage and an answer, generate a question for the given answer.

Let me give you an example: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
The answer to this example can be: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Here is why: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

OK. solve this:
Passage: Enzymes are extremely efficient in speeding up reactions. They can catalyze up to several million reactions per second. As a result, the difference in rates of biochemical reactions with and without enzymes may be enormous. A typical biochemical reaction might take hours or even days to occur under normal cellular conditions without an enzyme, but less than a second with an enzyme. Answer: speed it up
Answer:
Enzymes in cellular reactions work to do what to the reaction?