In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
One example is below.
Q: Question: A 13-year-old girl is operated on due to Hirschsprung illness at 3 months of age. Which of the following tumors is more likely to be present?
Options: <1> Abdominal neuroblastoma <2> Wilms tumor <3> Mesoblastic nephroma <4> Familial thyroid medullary carcinoma.
A: 2
Rationale: The answer to the given question should be a tumor, therefore Wilms tumor is the correct answer for the given question.
Q: Question: What factors depends on the apparent volume of distribution of a drug ?:
Options: <1> Its degree of binding to plasma and tissue proteins and its elimination half-life. <2> Of its distribution coefficient and its elimination half-life. <3> Of its elimination half-life and its elimination constant. <4> Its degree of binding to plasma and tissue proteins and their distribution coefficient. <5> Of its constant elimination and its clearing.
A:
4