Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: The apolipoprotein E type 4 allele is a susceptibility gene for late-onset Alzheimer's disease. Apolipoprotein E is found in neurons, some of which contain paired helical filaments made of the microtubule-associated protein tau. Previous studies have demonstrated that the apoE3 isoform, but not the apoE4 isoform, binds tau with high avidity. Because the microtubule-associated protein MAP2c also effects microtubule assembly and stability, we examined interactions between apoE isoforms and MAP2c. Similar to the tau-binding results, apoE3, but not apoE4, bound MAP2c. Binding was detectable down to 10(-9) M MAP2c and 10(-8) M apoE3. Isoform-specific interactions of apoE with the microtubule-associated proteins MAP2c and tau might affect intracellular maintenance of microtubules and could contribute to a time-dependent pathogenesis of Alzheimer's disease.
[EX A]: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?

[EX Q]: According to the United States Department of Labors Bureau of Labor Statistics, there were approximately 210,900 physical therapists employed in the United States in 2014, earning an average $84,020 annually in 2015, or $40.40 per hour, with 34% growth in employment projected by the year 2024. The Bureau of Labor Statistics also reports that there were approximately 128,700 Physical Therapist Assistants and Aides employed in the United States in 2014, earning an average $42,980 annually, or $20.66 per hour, with 40% growth in employment projected by the year 2024. To meet their needs, many healthcare and physical therapy facilities hire "travel physical therapists", who work temporary assignments between 8 and 26 weeks for much higher wages; about $113,500 a year. Bureau of Labor Statistics data on PTAs and Techs can be difficult to decipher, due to their tendency to report data on these job fields collectively rather than separately. O-Net reports that in 2015, PTAs in the United States earned a median wage of $55,170 annually or $26.52 hourly, and that Aides/Techs earned a median wage of $25,120 annually or $12.08 hourly in 2015. The American Physical Therapy Association reports vacancy rates for physical therapists as 11.2% in outpatient private practice, 10% in acute care settings, and 12.1% in skilled nursing facilities. The APTA also reports turnover rates for physical therapists as 10.7% in outpatient private practice, 11.9% in acute care settings, 27.6% in skilled nursing facilities.
[EX A]: What group has the highest percentage of vacancy for Physical Therapist Assistants?

[EX Q]: However, the Seven Years' War ended on February 10, 1763 with the signing of the Treaty of Paris in Paris, France. Also, Silang was assassinated on May 28, 1763 by an Indio under the employ of the friars. The Spanish were then able to focus on the uprising and mustered forces to surround Palaris. The Spanish friars, who were allowed to stay in the province, also started a campaign to persuade Pangasinan residents of the futility of the Palaris Revolt. By September 1763, news of the peace treaty reached Pangasinan and army of Palaris' men surrendered and returned to normal life amid the Spanish offensive. Palaris tried to fend off the offensive at the village of Mabalitec near the Agno River between Binalatongan and Bayambang in December 1763. To prevent the Spanish from seeking lodging in his hometown, he ordered his men to raze Binalatongan. But the Spanish won the Battle of Mabalitec, demoralizing Palaris' forces. The town of Binalatongan was rebuilt in another site between December 1763 to June 1764 and renamed San Carlos , in honor of the reigning King Carlos III of Spain. Palaris' forces made a last stand at the town of San Jacinto, Pangasinan, but they were defeated. Palaris' advisers, Andres Lopez and Juan de Vera Oncantin, were captured. They would later be hanged.
[EX A]:
Who returned to normal life?