Detailed Instructions: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
Problem:Paragraph: Foot-and-mouth disease virus (FMDV) leader protein (L pro ) is a papain-like proteinase, which plays an important role in FMDV pathogenesis. L pro exists as two forms, Lab and Lb, due to translation being initiated from two different start codons separated by 84 nucleotides. L pro self-cleaves from the nascent viral polyprotein precursor as the first mature viral protein. In addition to its role as a viral proteinase, L pro also has the ability to antagonize host antiviral effects. To promote FMDV replication, L pro can suppress host antiviral responses by three different mechanisms: (1) cleavage of eukaryotic translation initiation factor 4 (eIF4G) to shut off host protein synthesis; (2) inhibition of host innate immune responses through restriction of interferon-/ production; and (3) L pro can also act as a deubiquitinase and catalyze deubiquitination of innate immune signaling molecules. In the light of recent functional and biochemical findings regarding L pro , this review introduces the basic properties of L pro and the mechanisms by which it antagonizes host antiviral responses. ©️ 2015 Liu et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http:// creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/
Title: Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses
Solution:
False