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How to make a graphical abstract for scientific publication
Consider the scope of your study.
The goal is to express the main point of your study in an easily digestible image, therefore it is important that you center your graphical abstract around the concept of your research. If you are studying a particular molecular change, make sure that the mechanism is part of your image.
Likewise, if you are working with one particular genome, include some important piece of it in your image. You can find an open source image or create one yourself.