Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Do novel meta-analysis-derived type 2 diabetes risk loci determine prediabetic phenotypes?
Answer: In contrast to the first series of GWA-derived type 2 diabetes candidate SNPs, we could not detect reliable associations of the novel risk loci with prediabetic phenotypes. Possible weak effects of ADAMTS9 SNP rs4607103 and VEGFA SNP rs9472138 on insulin sensitivity and insulin secretion, respectively, await further confirmation by larger studies.

Answer: no

Question: Question: Is prooxidant-anti-oxidant balance associated with extent of coronary artery disease?
Answer: In conclusion, we found higher levels of oxidative stress in CAD+ patients compared to healthy subjects. The oxidation level was not related to measures of the extent of CAD such as number of stenosed vessels.

Answer: no

Question: Question: Does ketamine inhibit proliferation of neural stem cell from neonatal rat hippocampus in vitro?
Answer: Ketamine inhibited proliferation of NSCs from neonatal rat hippocampus in vitro. Suppressing Ca(2+)-PKC-ERK1/2 signaling pathway may be involved in this inhibitory effect of ketamine on NSCs proliferation.

Answer:
yes