TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does peroxiredoxin 1 promote pancreatic cancer cell invasion by modulating p38 MAPK activity?
Answer: Prdx1 associates with the formation of membrane protrusions through modulation of the activity of p38 MAPK, which in turn promotes PDAC cell invasion.

SOLUTION: yes

PROBLEM: Question: Is cDK10 a target for aberrant DNA methylation in breast cancer?
Answer: CDK10 is not a target for aberrant DNA methylation in breast cancer.

SOLUTION: no

PROBLEM: Question: Does severe leukoaraiosis portend a poor outcome after traumatic brain injury?
Answer: We provide first evidence that preexisting cerebral small vessel disease independently predicts a poor functional outcome after closed head TBI. This association is independent of other established outcome predictors such as age, comorbid state as well as intensive care unit complications and interventions. This knowledge may help improve prognostic accuracy, clinical management, and resource utilization.

SOLUTION:
yes