Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
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Question: Context: Alpha-synuclein(-syn) is the main protein component of Lewy bodies (LBs), that together with nigrostriatal dopamine neuron loss constitute typical pathological hallmarks of Parkinson's disease (PD). Glutamate N-methyl-d-aspartate receptor (NMDAR) abnormalities, peculiarly involving NR2B-containing NMDAR, have been observed in the brain of PD patients and in several experimental models of the disease. Recent findings, indicating that -syn can modulate NMDAR trafficking and function, suggest that this protein may be a pivotal regulator of NMDAR activity. Prompted by these evidences, we used fluorescence immunocytochemistry, western blotting and ratiometric Ca(2+) measurements to investigate whether wild type (wt) or C-terminally truncated -syn can specifically modulate NR2B-containing NMDAR levels, subcellular trafficking and function. In addition, we evaluated whether the exposure of primary cortical neurons to increasing concentrations of rotenone could differentially regulate NR2B levels and cell viability in the presence or in the absence of -syn. Our results indicate that both wt and C-terminally truncated -syn negatively modulate NR2B-containing NMDAR levels, membrane translocation and function. Moreover, we found that absence of -syn abolishes the rotenone-dependent decrease of NR2B levels and reduces neuronal vulnerability in primary cortical neurons. These findings suggest that -syn can modulate neuronal resilience by regulating NR2B-containing NMDAR, whose specific alterations could connect -syn pathology to neuronal degeneration in PD.
Question: Which is the primary protein component of Lewy bodies?

Answer: syn

Question: Context: Fluorescence in situ hybridization (FISH) technique has been successfully used to detect the BCR-ABL gene fusion in chronic myeloid leukemia (CML) with the classic form of the Philadelphia chromosome (Ph). We applied FISH to study three CML patients showing variant Ph chromosome (either complex or simple type). The results demonstrate that the use of a yeast artificial chromosome (YAC)-derived probe (D107F9) and a cosmid probe (cos-abl 8), specific for BCR and ABL genes respectively, allows also the detection of the BCR-ABL fusion in CML patients with variant Ph.
Question: Which gene fusion is the result of the "philadelphia translocation" or the "philadelphia chromosome" mutation?

Answer: the bcr/abl gene fusion

Question: Context: As of the census of 2000, there were 35,100 people, 12,759 households, and 9,071 families residing in the county. The population density was 59 people per square mile (23/km). There were 15,035 housing units at an average density of 25 per square mile (10/km). The racial makeup of the county was 85.8% Race (United States Census), 3.9% Race (United States Census) or Race (United States Census), 1.8% Race (United States Census), 1.0% Race (United States Census), 0.1% Race (United States Census), 5.0% from Race (United States Census), and 2.4% from two or more races. 8.9% of the population were Race (United States Census) or Race (United States Census) of any race. 14.9% were of German people, 12.6% English people, 11.7% Irish people, 8.8% Italian people and 7.3% United States ancestry according to Census 2000. 93.1% spoke English language and 5.1% Spanish language as their first language.
Question: Which ancestral group is larger: Irish or Italian?

Answer:
irish