Given a scientific passage and an answer, generate a question for the given answer.

Example input: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Example output: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Example explanation: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.
Q: Passage: Enzymes are proteins that increase the rate of biochemical reactions. Enzymes aren't changed or used up in the reactions, so they can be used to speed up the same reaction over and over again. Enzymes are highly specific for certain chemical reactions, so they are very effective. A reaction that would take years to occur without its enzyme might occur in a split second with the enzyme. Answer: enzymes
A:
What are proteins that increase the rate of biochemical reactions?