Detailed Instructions: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Q: Question: Is hER2 amplification level a prognostic factor for HER2-positive breast cancer with trastuzumab-based adjuvant treatment : a systematic review and meta-analysis?
Answer: HER2 amplification level is not a prognostic factor for HER2-positive breast cancer with trastuzumab-based targeted therapy in the clinical adjuvant setting.
A:
no