Information: - Nevus (plural: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. The term originates from "nvus", which is Latin for "birthmark," however, a nevus can be either congenital (present at birth) or acquired. Common terms, including mole, birthmark, and beauty mark, are used to describe nevi, but these terms do not distinguish specific types of nevi. - A birthmark is a congenital, benign irregularity on the skin which is present at birth or appears shortly after birth, usually in the first month. They can occur anywhere on the skin. Birthmarks are caused by overgrowth of blood vessels, melanocytes, smooth muscle, fat, fibroblasts, or keratinocytes. - A melanocytic nevus (also known as "nevocytic nevus") is a type of lesion that contains nevus cells (a type of melanocyte). Some sources equate the term mole with "melanocytic nevus". Other sources reserve the term "mole" for other purposes. - A lesion is any abnormal damage or change in the tissue of an organism, usually caused by disease or trauma. "Lesion" is derived from the Latin word "laesio" meaning "injury". Lesions may occur in plants as well as animals. - Nevus cells are a variant of melanocytes. They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules. They are usually located at the dermoepidermal junction or in the dermis of the skin. Dermal nevus cells can be further classified: type A (epithelioid) dermal nevus cells mature into type B (lymphocytoid) dermal nevus cells which mature further into type C (neuroid) dermal nevus cells, through a process involving downwards migration. - Melanocytes (or ) are melanin-producing neural-crest derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, meninges, bones, and heart. Melanin is the pigment primarily responsible for skin color. Once synthesised, melanin is contained in a special organelle called a melanosome and moved along arm-like structures called dendrites, so as to reach the keratinocytes. - A dysplastic nevus or atypical mole is a nevus ( mole ) whose appearance is different from that of common moles . In 1992 , the NIH recommended that the term '' dysplastic nevus '' be avoided in favor of the term '' atypical mole '' . An atypical mole may also be referred to as an atypical melanocytic nevus , atypical nevus , B - K mole , Clark 's nevus , dysplastic melanocytic nevus , or nevus with architectural disorder . Dysplastic nevi often grow to larger than ordinary moles , and may have irregular and indistinct borders . Their color may not be uniform , and may range from light pink to very dark brown . They usually begin as flat , but parts may raise above the skin surface . See ABCDE and '' ugly duckling '' characteristics below . Dysplastic nevi can be found anywhere , but are most common on the trunk in men , and on the calves in women . - Skin is the soft outer covering of vertebrates. Other animal coverings, such as the arthropod exoskeleton have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin "cutis", skin). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue, and guards the underlying muscles, bones, ligaments and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. All mammals have some hair on their skin, even marine mammals like whales, dolphins, and porpoises which appear to be hairless. The skin interfaces with the environment and is the first line of defense from external factors. For example, the skin plays a key role in protecting the body against pathogens and excessive water loss. Its other functions are insulation, temperature regulation, sensation, and the production of vitamin D folates. Severely damaged skin may heal by forming scar tissue. This is sometimes discoloured and depigmented. The thickness of skin also varies from location to location on an organism. In humans for example, the skin located under the eyes and around the eyelids is the thinnest skin in the body at 0.5mm thick, and is one of the first areas to show signs of aging such as "crows feet" and wrinkles. The skin on the palms and the soles of the feet is 4mm thick and the back is 14mm thick and is the thickest skin in the body. The speed and quality of wound healing in skin is promoted by the reception of estrogen. What is the relationship between 'dysplastic nevus' and 'disease'?
The answer to this question is:
subclass of