Given the task definition and input, reply with output. Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does apelin-13 protect the heart against ischemia-reperfusion injury through the RISK-GSK-3-mPTP pathway?
Answer: The protective mechanism of apelin-13 might be that inactivation of GSK-3 could inhibit the opening of mPTP by activating PI3K/Akt and ERK1/2 involved in the reperfusion injury salvage kinase (RISK) pathway.
yes