In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.
One example: Question: A distension is defined as:
Options: <0> Soft tissue injury. <1> Forced movement of abrupt production. <2> Injury by stretching a muscle. <3> Injury of the joint capsule. <4> Interruption in the continuity of a bone.
Solution is here: nursery
Explanation: Distension means Bloating and swelling in the belly area. It does not have much to do with chemistry, psychology, pharmacology, biology and medicine. Hence, the correct topic is nursery.

Now, solve this: Question: To estimate the plasma clearance of a drug (CLIR) that presents a linear kinetic behavior and is excreted significantly in the urine, in a patient with renal failure (RI), it is necessary to know:
Options: <0> Clearance of creatinine in the uremic patient (CLcrIR) and in individuals with normal renal function (CLcrFRN). <1> The renal clearance of the drug in patients with normal renal function (CLrFRN), CLcrIR and CLcrFRN. <2> The fraction of drug excreted in unaltered form in the urine (fr), the dose administered (D), CLrFRN, CLcrIR and CLcrFRN. <3> fr, CLcrIR and CLcrFRN and the plasma clearance of the drug in patients with normal renal function <4> fr, CLrFRN, CLcrIR, CLcrFRN and D.
Solution:
pharmacology