Context and question: The thalidomide tragedy resurrected Kefauver's bill to enhance drug regulation that had stalled in Congress, and the Kefauver-Harris Amendment became law on 10 October 1962. Manufacturers henceforth had to prove to FDA that their drugs were effective as well as safe before they could go on the US market. The FDA received authority to regulate advertising of prescription drugs and to establish good manufacturing practices. The law required that all drugs introduced between 1938 and 1962 had to be effective. An FDA - National Academy of Sciences collaborative study showed that nearly 40 percent of these products were not effective. A similarly comprehensive study of over-the-counter products began ten years later.
What did the National Academy of Science's study discover?
Answer: nearly 40 percent of these products were not effective
Context and question: It is not clearly documented when the title of the Grand Duke was first introduced, but the importance of the Kiev principality was recognized after the death of Sviatoslav I in 972 and the ensuing struggle between Vladimir the Great and Yaropolk I. The region of Kiev dominated the state of Kievan Rus' for the next two centuries. The Grand Prince ("velikiy kniaz'") of Kiev controlled the lands around the city, and his formally subordinate relatives ruled the other cities and paid him tribute. The zenith of the state's power came during the reigns of Vladimir the Great (9801015) and Prince Yaroslav I the Wise (10191054). Both rulers continued the steady expansion of Kievan Rus' that had begun under Oleg.
What year was the struggle between Vladimir the Great and Yaropolk I?
Answer: unanswerable
Context and question: The first known smelting of iron began in Anatolia, around 1800 BC. Called the bloomery process, it produced very soft but ductile wrought iron. By 800 BC, iron-making technology had spread to Europe, arriving in Japan around 700 AD. Pig iron, a very hard but brittle alloy of iron and carbon, was being produced in China as early as 1200 BC, but did not arrive in Europe until the Middle Ages. Pig iron has a lower melting point than iron, and was used for making cast-iron. However, these metals found little practical use until the introduction of crucible steel around 300 BC. These steels were of poor quality, and the introduction of pattern welding, around the 1st century AD, sought to balance the extreme properties of the alloys by laminating them, to create a tougher metal. Around 700 AD, the Japanese began folding bloomery-steel and cast-iron in alternating layers to increase the strength of their swords, using clay fluxes to remove slag and impurities. This method of Japanese swordsmithing produced one of the purest steel-alloys of the early Middle Ages.
What smelting process was developed in 800 A.D.?
Answer:
unanswerable