Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: In the mean time, Maha Nawrahta opened the southern front on 23 October 1765 in three directions. He had 20,000 to 30,000 under his command. A small army invaded by the Three Pagodas Pass towards Suphanburi. Another small army invaded down the Tenasserim coast towards Mergui and Tenasserim town. However, the main thrust of his attack was at Kanchanaburi. His 20,000-strong main southern army invaded via the Myitta Pass. Kanchanaburi fell with little resistance. The main reason for the quick fall of Kanchanaburi could be that the Burmese were more battle-hardened. But it could also be that the Siamese command miscalculated where the Burmese main attack would come from, and had not sufficiently reinforced the fort to withstand a major attack. Judging by the Siamese chronicles' reporting of the main attack route, the Siamese command appeared to have believed that the main Burmese attack would come from the Gulf of Siam coastline, instead of the most obvious and shortest route via Kanchanaburi. The Siamese sources say that Maha Nawrahta's main invasion route came from southern Tenasserim, crossing the Tenasserim range at Chumphon and Phetburi. The path is totally different from the Kanchanaburi route reported by the Burmese chronicles. Historian Kyaw Thet specifically adds that the main attack route was via the Myitta Pass.
[EX A]: How many Maha Nawrahta opened the southern front?

[EX Q]: Urgent surgery or life-threatening bleeding requires prompt reversal of the anticoagulant effects of dabigatran. This study assessed the ability of three- and four-factor prothrombin complex concentrate (PCC) and idarucizumab (specific antidote for dabigatran) to reverse the anticoagulant effects of dabigatran in a porcine model of trauma. Twelve animals were given dabigatran etexilate (DE) orally and dabigatran intravenously, before infliction of trauma. Six animals received tranexamic acid plus fibrinogen concentrate 12 minutes post-injury. Six PCCs (each 30 and 60 U/kg) and idarucizumab (30 and 60 mg/kg) were added to blood samples ex vivo. Coagulation was assessed by several coagulation assays. All coagulation parameters were altered after dabigatran infusion (plasma level: 442 138 ng/ml). Both three- and four-factor PCCs mostly or completely reversed the effects of dabigatran on thromboelastometry variables and PT but not on aPTT. Idarucizumab neutralised plasma concentrations of dabigatran, and reversed the effects of the drug on coagulation variables. Thrombin generation showed dose-dependent over-correction following the addition of PCC, implying that elevated levels of thrombin are required to overcome dabigatran-induced coagulopathy. In contrast, treatment with idarucizumab returned thrombin generation to baseline levels. Following trauma, therapy with tranexamic acid plus fibrinogen improved correction of coagulation parameters by PCC, and thromboelastometry parameters by idarucizumab. All investigated PCCs improved dabigatran- and trauma-induced coagulopathy to a similar degree. In conclusion, this study shows that three- and four-factor PCCs are similarly effective for dabigatran reversal. Idarucizumab also reversed the effects of dabigatran and, unlike PCCs, was not associated with over-correction of thrombin generation.
[EX A]: Which drug can be reversed with idarucizumab?

[EX Q]: The water that comes out of our faucets is safe because it has gone through a series of treatment and purification processes to remove contaminants. Those of us who are fortunate enough to always be able to get clean water from a tap in our home may have trouble imagining life in a country that cannot afford the technology to treat and purify water. Many people in the world have no choice but to drink from the same polluted river where sewage is dumped. One- fifth of all people in the world, more than 1.1 billion people, do not have access to safe water for drinking, personal cleanliness, and domestic use. Unsafe drinking water carries many pathogens, or disease-causing biological agents such as infectious bacteria and parasites. Toxic chemicals and radiological hazards in water can also cause diseases. Waterborne disease caused by unsafe drinking water is the leading cause of death for children under the age of five in many nations and a cause of death and illness for many adults. About 88% of all diseases are caused by drinking unsafe water (Figure 1.1). Throughout the world, more than 14,000 people die every day from waterborne diseases, such as cholera, and many of the worlds hospital beds are occupied by patients suffering from a waterborne disease. Guinea worm is a serious problem in parts of Africa that is being eradicated. Learn what is being done to decrease the number of people suffering from this parasite at the video below. Click image to the left or use the URL below. URL:
[EX A]:
________________ of all people in the world have access to safe water for drinking, personal cleanliness, and domestic use.