Teacher:Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Teacher: Now, understand the problem? Solve this instance: Question: Is downregulation of microRNAs 145-3p and 145-5p a long-term predictor of postmenopausal breast cancer risk : The ORDET prospective study?
Answer: These observations and the prospective design of our study lend support to the hypothesis that downregulation of specific miRNAs constitutes an early event in cancer development. This finding might be used for breast cancer prevention.
Student:
yes