Problem: Digestion:

In addition to the use of the multiprotein complexes listed above, Gram-negative bacteria possess another method for release of material: the formation of outer membrane vesicles. Portions of the outer membrane pinch off, forming spherical structures made of a lipid bilayer enclosing periplasmic materials. Vesicles from a number of bacterial species have been found to contain virulence factors, some have immunomodulatory effects, and some can directly adhere to and intoxicate host cells. While release of vesicles has been demonstrated as a general response to stress conditions, the process of loading cargo proteins seems to be selective.

What does the release of vesicles seem to demenstrate?
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A: response to stress conditions

Problem: Tuberculosis:

Slow progress has led to frustration, expressed by executive director of the Global Fund to Fight AIDS, Tuberculosis and Malaria Mark Dybul: "we have the tools to end TB as a pandemic and public health threat on the planet, but we are not doing it." Several international organizations are pushing for more transparency in treatment, and more countries are implementing mandatory reporting of cases to the government, although adherence is often sketchy. Commercial treatment-providers may at times overprescribe second-line drugs as well as supplementary treatment, promoting demands for further regulations. The government of Brazil provides universal TB-care, which reduces this problem. Conversely, falling rates of TB-infection may not relate to the number of programs directed at reducing infection rates, but may be tied to increased level of education, income and health of the population. Costs of the disease, as calculated by the World Bank in 2009 may exceed 150 billion USD per year in "high burden" countries. Lack of progress eradicating the disease may also be due to lack of patient follow-up as among the 250M rural migrants in China.

What population segment in China struggles to get follow-up care for TB infection?
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A: rural migrants

Problem: Somerset:

There is an extensive network of caves, including Wookey Hole, underground rivers, and gorges, including the Cheddar Gorge and Ebbor Gorge. The county has many rivers, including the Axe, Brue, Cary, Parrett, Sheppey, Tone and Yeo. These both feed and drain the flat levels and moors of mid and west Somerset. In the north of the county the River Chew flows into the Bristol Avon. The Parrett is tidal almost to Langport, where there is evidence of two Roman wharfs. At the same site during the reign of King Charles I, river tolls were levied on boats to pay for the maintenance of the bridge.

Name some of the county rivers
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A: the Axe, Brue, Cary, Parrett, Sheppey, Tone and Yeo

Problem: Culture:

In the United States, "Cultural Studies" focuses largely on the study of popular culture, that is, on the social meanings of mass-produced consumer and leisure goods. Richard Hoggart coined the term in 1964 when he founded the Birmingham Centre for Contemporary Cultural Studies or CCCS. It has since become strongly associated with Stuart Hall, who succeeded Hoggart as Director. Cultural studies in this sense, then, can be viewed as a limited concentration scoped on the intricacies of consumerism, which belongs to a wider culture sometimes referred to as "Western Civilization" or as "Globalism."

Who first coined the term "Cultural Studies" in the United States?
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A:
Richard Hoggart