Article: The body's capability to react to antigen depends on a person's age, antigen type, maternal factors and the area where the antigen is presented. Neonates are said to be in a state of physiological immunodeficiency, because both their innate and adaptive immunological responses are greatly suppressed. Once born, a child's immune system responds favorably to protein antigens while not as well to glycoproteins and polysaccharides. In fact, many of the infections acquired by neonates are caused by low virulence organisms like Staphylococcus and Pseudomonas. In neonates, opsonic activity and the ability to activate the complement cascade is very limited. For example, the mean level of C3 in a newborn is approximately 65% of that found in the adult. Phagocytic activity is also greatly impaired in newborns. This is due to lower opsonic activity, as well as diminished up-regulation of integrin and selectin receptors, which limit the ability of neutrophils to interact with adhesion molecules in the endothelium. Their monocytes are slow and have a reduced ATP production, which also limits the newborn's phagocytic activity. Although, the number of total lymphocytes is significantly higher than in adults, the cellular and humoral immunity is also impaired. Antigen-presenting cells in newborns have a reduced capability to activate T cells. Also, T cells of a newborn proliferate poorly and produce very small amounts of cytokines like IL-2, IL-4, IL-5, IL-12, and IFN-g which limits their capacity to activate the humoral response as well as the phagocitic activity of macrophage. B cells develop early during gestation but are not fully active.

Question: Antigen cells in newborns are also struggle to do this?
Ans: activate T cells

Article: On 21 December 1941, the Partisans created the First Proletarian Brigade (commanded by Koca Popovic) and on 1 March 1942, Tito created the Second Proletarian Brigade. In liberated territories, the Partisans organised People's Committees to act as civilian government. The Anti-Fascist Council of National Liberation of Yugoslavia (AVNOJ) convened in Bihac on 2627 November 1942 and in Jajce on 29 November 1943. In the two sessions, the resistance representatives established the basis for post-war organisation of the country, deciding on a federation of the Yugoslav nations. In Jajce, a 67-member "presidency" was elected and established a nine-member National Committee of Liberation (five communist members) as a de facto provisional government. Tito was named President of the National Committee of Liberation.

Question: When did Tito create the Second Proletarian Brigade?
Ans: 1942

Article: Phase-two mode can only be activated by a key switch located inside the elevator on the centralized control panel. This mode was created for firefighters so that they may rescue people from a burning building. The phase-two key switch located on the COP has three positions: off, on, and hold. By turning phase two on, the firefighter enables the car to move. However, like independent-service mode, the car will not respond to a car call unless the firefighter manually pushes and holds the door close button. Once the elevator gets to the desired floor it will not open its doors unless the firefighter holds the door open button. This is in case the floor is burning and the firefighter can feel the heat and knows not to open the door. The firefighter must hold door open until the door is completely opened. If for any reason the firefighter wishes to leave the elevator, they will use the hold position on the key switch to make sure the elevator remains at that floor. If the firefighter wishes to return to the recall floor, they simply turn the key off and close the doors.

Question: What actions must a firefighter take to activate Phase-two mode?
Ans: manually pushes and holds the door close button

Article: 14th Street is a main numbered street in Manhattan. It begins at Avenue C and ends at West Street. Its length is 3.4 km (2.1 mi). It has six subway stations:

Question: What is the length of 14th Street in miles?
Ans:
2.1