In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Example input: The severe acute respiratory syndrome (SARS) epidemic originating from China in 2002 was caused by a previously uncharacterized coronavirus that could be identified by specific RT-PCR amplification. Efforts to control future SARS outbreaks depend on the accurate and early identification of SARS-CoV infected patients. A real-time fluorogenic RT-PCR assay based on the 3 -noncoding region (3 -NCR) of SARS-CoV genome was developed as a quantitative SARS diagnostic tool. The ideal amplification efficiency of a sensitive SARS-CoV RT-PCR assay should yield an E value (PCR product concentration increase per amplification cycle) equal to 2.0. It was demonstrated that the 3 -NCR SARS-CoV based RT-PCR reactions could be formulated to reach excellent E values of 1.81, or 91% amplification efficacy. The SARS-CoV cDNA preparations derived from viral RNA extract and the cloned recombinant plasmid both exhibit the identical amplification characteristics, i.e. amplification efficacy using the same PCR formulation developed in this study. The viral genomic copy (or genomic equivalences, GE) per infectious unit (GE/pfu) of SARS-CoV used in this study was also established to be approximate 1200-1600:1. The assay's detection sensitivity could reach 0.005 pfu or 6-8 GE per assay. It was preliminarily demonstrated that the assay could efficiently detect SARS-CoV from clinical specimens of SARS probable and suspected patients identified in Taiwan. The 3 -NCR based SARS-CoV assay demonstrated 100% diagnostic specificity testing samples of patients with acute respiratory disease from a non-SARS epidemic region.
Example output: Development and evaluation of an efficient 3 -noncoding region-based SARS coronavirus (SARS-CoV) RT-PCR assay for detection of SARS-CoV
Example explanation: It's a correct title because the paragraph described the development of 3 -noncoding region of SARS-CoV genome and assay efficiently detecting SARS-CoV from clinical specimens.
Q: York, UK, was a good choice for the venue of this workshop because the history of nucleolar research-like the city-falls into distinct eras. Founded by the Romans in 71 AD, York has been occupied at various points in time by the Saxons, Vikings and Normans. Our understanding of the nucleolus has also followed a pattern in which rapid advances have been interspersed with periods of relative dormancy. The nucleolus was first observed early in the nineteenth century, but it was not until the 1960s that its role in ribosome biogenesis was established. After that, it was assumed that the nucleolus did not do much else; however, to our surprise, many unexpected roles for the nucleolus have emerged in the past decade. The textbook view of the nucleolus shows a fibrillar centre surrounded by a ring of dense fibrillar components, with granular components scattered throughout the body of the nucleolus. However, D. Lafontaine (Brussels, Belgium) reminded us that most eukaryotes have only two subcompartments and lack the fibrillar centre (Thiry & Lafontaine, 2005) . This division between bipartite and tripartite nucleoli seems to have been a recent evolutionary event that
A:
What is new in the nucleolus? Workshop on the Nucleolus: New Perspectives