Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: In the mean time, Maha Nawrahta opened the southern front on 23 October 1765 in three directions. He had 20,000 to 30,000 under his command. A small army invaded by the Three Pagodas Pass towards Suphanburi. Another small army invaded down the Tenasserim coast towards Mergui and Tenasserim town. However, the main thrust of his attack was at Kanchanaburi. His 20,000-strong main southern army invaded via the Myitta Pass. Kanchanaburi fell with little resistance. The main reason for the quick fall of Kanchanaburi could be that the Burmese were more battle-hardened. But it could also be that the Siamese command miscalculated where the Burmese main attack would come from, and had not sufficiently reinforced the fort to withstand a major attack. Judging by the Siamese chronicles' reporting of the main attack route, the Siamese command appeared to have believed that the main Burmese attack would come from the Gulf of Siam coastline, instead of the most obvious and shortest route via Kanchanaburi. The Siamese sources say that Maha Nawrahta's main invasion route came from southern Tenasserim, crossing the Tenasserim range at Chumphon and Phetburi. The path is totally different from the Kanchanaburi route reported by the Burmese chronicles. Historian Kyaw Thet specifically adds that the main attack route was via the Myitta Pass.

Answer: How many Maha Nawrahta opened the southern front?

Question: The effect of the newly synthesized compound 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline (SEA0400) on the Na+-Ca2+ exchanger (NCX) was investigated and compared against that of 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea (KB-R7943). In addition, the effects of SEA0400 on reperfusion injury in vitro and in vivo were examined. SEA0400 was extremely more potent than KB-R7943 in inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia: IC50s of SEA0400 and KB-R7943 were 5 to 33 nM and 2 to 4 microM, respectively. SEA0400 at the concentration range that inhibited NCX exhibited negligible affinities for the Ca2+ channels, Na+ channels, K+ channels, norepinephrine transporter, and 14 receptors, and did not affect the activities of the Na+/H+ exchanger, Na+,K+-ATPase, Ca2+-ATPase, and five enzymes. SEA0400, unlike KB-R7943, did not inhibit the store-operated Ca2+ entry in cultured astrocytes. SEA0400 attenuated dose- dependently paradoxical Ca2+ challenge-induced production of reactive oxygen species, DNA ladder formation, and nuclear condensation in cultured astrocytes, whereas it did not affect thapsigargin-induced cell injury. Furthermore, administration of SEA0400 reduced infarct volumes after a transient middle cerebral artery occlusion in rat cerebral cortex and striatum. These results indicate that SEA0400 is the most potent and selective inhibitor of NCX, and suggest that the compound may exert protective effects on postischemic brain damage.

Answer: The small molecule SEA0400 is an inhibitor of which ion antiporter/exchanger?

Question: British author JK Rowling was at the release of her latest Harry Potter book called "Harry Potter and the Deathly Hallows" at the Natural History Museum in London, Friday July 20, 2007. J.K. Rowling has been spotted at cafes in Scotland working on a detective novel, a British newspaper reported Saturday. The Sunday Times newspaper quoted Ian Rankin, a fellow author and neighbor of Rowling's, as saying the creator of the "Harry Potter" books is turning to crime fiction. "My wife spotted her writing her Edinburgh criminal detective novel," the newspaper quoted Rankin as telling a reporter at an Edinburgh literary festival. "It is great that she has not abandoned writing or Edinburgh cafes," said Rankin, who is known for his own police novels set in the historic Scottish city. Rowling famously wrote initial drafts of the Potter story in the Scottish city's cafes. Back then, she was a struggling single mother who wrote in cafes to save on the heating bill at home. Now she's Britain's richest woman - worth $1 billion, according to Forbes magazine - and her seven Potter books have sold more than 335 million copies worldwide. In an interview with The Associated Press last month, Rowling said she believed she was unlikely to repeat the success of the Potter series, but confirmed she had plans to work on new books. "I'll do exactly what I did with Harry - I'll write what I really want to write," Rowling said.

Answer:
What is JK Rowling famous for?