Problem: Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which hinders the entry of drugs and makes many antibiotics ineffective. The two antibiotics most commonly used are isoniazid and rifampicin, and treatments can be prolonged, taking several months. Latent TB treatment usually employs a single antibiotic, while active TB disease is best treated with combinations of several antibiotics to reduce the risk of the bacteria developing antibiotic resistance. People with latent infections are also treated to prevent them from progressing to active TB disease later in life. Directly observed therapy, i.e., having a health care provider watch the person take their medications, is recommended by the WHO in an effort to reduce the number of people not appropriately taking antibiotics. The evidence to support this practice over people simply taking their medications independently is poor. Methods to remind people of the importance of treatment do, however, appear effective.
What complication does the use of combinations of antibiotics for active TB prevent?
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Answer: antibiotic resistance

Problem: The earliest known American lodges were in Pennsylvania. The Collector for the port of Pennsylvania, John Moore, wrote of attending lodges there in 1715, two years before the formation of the first Grand Lodge in London. The Premier Grand Lodge of England appointed a Provincial Grand Master for North America in 1731, based in Pennsylvania. Other lodges in the colony obtained authorisations from the later Antient Grand Lodge of England, the Grand Lodge of Scotland, and the Grand Lodge of Ireland, which was particularly well represented in the travelling lodges of the British Army. Many lodges came into existence with no warrant from any Grand Lodge, applying and paying for their authorisation only after they were confident of their own survival.
Where were the earliest known American Logdes located?
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Answer: Pennsylvania

Problem: Once inside the Rotunda for the Charters of Freedom, there are no lines to see the individual documents and visitors are allowed to walk from document to document as they wish. For over 30 years the National Archives have forbidden flash photography but the advent of cameras with automatic flashes have made the rules increasingly difficult to enforce. As a result, all filming, photographing, and videotaping by the public in the exhibition areas has been prohibited since February 25, 2010.
What has made the no photography rule hard to enforce in the Rotunda for the Charters of Freedom?
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Answer:
advent of cameras with automatic flashes