Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Is radiological review of specimen radiographs after breast localisation biopsy always necessary?
Answer: This study shows that a suitably trained or experienced surgeon can assess specimen radiographs effectively without the need for intraoperative radiological input although complete histological resection is not guaranteed despite specimen radiographs demonstrating clear margins.
no

Question: Does cYP3A5 genotype influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients?
Answer: This study provides direct and indirect evidence that CYP3A5 genotyping cannot help improve everolimus therapy.
no

Question: Does acid ceramidase treatment enhance the outcome of autologous chondrocyte implantation in a rat osteochondral defect model?
Answer: The results further demonstrate the positive effects of rhAC treatment on chondrocyte growth and phenotype in vitro, and reveal for the first time the in vivo effects of the treated cells on cartilage repair.
yes