Did Sugar Ray Robinson win a fight against Canelo Alvarez?
Sugar Ray Robinson died in 1989. Canelo Alvarez was born in 1990.
The answer is no.

Do guitarist's have fingers that can handle pain better than average?
Guitarists typically have calloused fingertips. Callouses are formed of layers of dead skin and usually lack sensation.
The answer is yes.

Is helium the cause of the Hindenburg explosion?
The Hindenburgh was filled with hydrogen. Helium is considered a noble, inert gas that doesn't react. Hydrogen is highly flammable.
The answer is no.

Did Robert Downey Jr. possess same caliber gun as Resident Evil's Barry Burton?
Robert Downey Jr. was arrested in 1996 n drug and weapons charges and possessed a .357 Magnum. Barry Burton, a character in the Resident Evil series, used a Colt Python. The Colt Python is a type of .357 Magnum revolver.
The answer is yes.