Q: Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
Paragraph: The cost of hormone replacement therapy is not in question. Of the 34,433 HRT users, 193 were diagnosed with colon cancer during the study period; that compared with 151 cases among the 13,778 women who had never used hormone replacement. HRT with either estrogen alone or a combination of estrogen and progestin was linked to a lower colon cancer risk even when the researchers accounted for the women's age, weight, exercise levels and race. Claim: Hormone replacement tied to lower colon cancer risk
A:
In only 546 words, this story covered most of the bases providing absolute data from a big trial, saying that the findings support earlier theories, but warning that this does not change earlier advice about HRT. This story was judicious and cautious two important characteristics in discussing hormone replacement therapy and colon cancer.