no
Question and rationale: The question is: Would fans of Jonathan Larson be unaware of HIV?
Jonathan Larson died of AIDS in 1996. Jonathan Larson produced music and plays about HIV, AIDS, and poverty.

no
Question and rationale: The question is: Did Secretariat win a Formula One championship?
Secretariat is a famous race horse. Formula One is an auto racing championship.

yes
Question and rationale:
The question is: Was the amount of spinach Popeye ate unhealthy?
Popeye was a cartoon character that ate whole cans of spinach to maintain his fighting strength. Spinach is high in oxalates which can lead to kidney stones. Too much spinach can lead to bloating, gas, fever, and diarrhea.