In fact, Whitehead describes any entity as in some sense nothing more and nothing less than the sum of its relations to other entities its synthesis of and reaction to the world around it. A real thing is just that which forces the rest of the universe to in some way conform to it; that is to say, if theoretically a thing made strictly no difference to any other entity (i.e. it was not related to any other entity), it could not be said to really exist. Relations are not secondary to what a thing is, they are what the thing is.
If an object made no difference to any other entity, what could be said about it?
not be said to really exist.

Human settlement of the New World occurred in stages from the Bering sea coast line, with an initial 15,000 to 20,000-year layover on Beringia for the small founding population. The micro-satellite diversity and distributions of the Y lineage specific to South America indicates that certain indigenous peoples of the Americas populations have been isolated since the initial colonization of the region. The Na-Dene, Inuit and Indigenous Alaskan populations exhibit haplogroup Q (Y-DNA) mutations, however are distinct from other indigenous peoples of the Americas with various mtDNA and atDNA mutations. This suggests that the earliest migrants into the northern extremes of North America and Greenland derived from later migrant populations.
How long of a layover did the human nomads have in Beringia?
15,000 to 20,000-year

Utrecht is the centre of a densely populated area, which makes concise definitions of its agglomeration difficult, and somewhat arbitrary. The smaller Utrecht agglomeration of continuously built up areas counts some 420,000 inhabitants and includes Nieuwegein, IJsselstein and Maarssen. It is sometimes argued that the close by municipalities De Bilt, Zeist, Houten, Vianen, Driebergen-Rijsenburg (Utrechtse Heuvelrug), and Bunnik should also be counted towards the Utrecht agglomeration, bringing the total to 640,000 inhabitants. The larger region, including slightly more remote towns such as Woerden and Amersfoort counts up to 820,000 inhabitants.
What does the dense population make difficult
which makes concise definitions of its agglomeration difficult, and somewhat arbitrary.