Part 1. Definition
In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
Part 2. Example
Paragraph: The severe acute respiratory syndrome (SARS) epidemic originating from China in 2002 was caused by a previously uncharacterized coronavirus that could be identified by specific RT-PCR amplification. Efforts to control future SARS outbreaks depend on the accurate and early identification of SARS-CoV infected patients. A real-time fluorogenic RT-PCR assay based on the 3 -noncoding region (3 -NCR) of SARS-CoV genome was developed as a quantitative SARS diagnostic tool. The ideal amplification efficiency of a sensitive SARS-CoV RT-PCR assay should yield an E value (PCR product concentration increase per amplification cycle) equal to 2.0. It was demonstrated that the 3 -NCR SARS-CoV based RT-PCR reactions could be formulated to reach excellent E values of 1.81, or 91% amplification efficacy. The SARS-CoV cDNA preparations derived from viral RNA extract and the cloned recombinant plasmid both exhibit the identical amplification characteristics, i.e. amplification efficacy using the same PCR formulation developed in this study. The viral genomic copy (or genomic equivalences, GE) per infectious unit (GE/pfu) of SARS-CoV used in this study was also established to be approximate 1200-1600:1. The assay's detection sensitivity could reach 0.005 pfu or 6-8 GE per assay. It was preliminarily demonstrated that the assay could efficiently detect SARS-CoV from clinical specimens of SARS probable and suspected patients identified in Taiwan. The 3 -NCR based SARS-CoV assay demonstrated 100% diagnostic specificity testing samples of patients with acute respiratory disease from a non-SARS epidemic region.
Title: Development and evaluation of an efficient 3 -noncoding region-based SARS coronavirus (SARS-CoV) RT-PCR assay for detection of SARS-CoV
Answer: True
Explanation: The answer is true because the title of the paragraph is correct where it described the development of 3 -noncoding region of SARS-CoV genome and assay efficiently detecting SARS-CoV from clinical specimens.
Part 3. Exercise
Paragraph: Background: Coronavirus disease 2019 is pandemic and has caused illness to many people worldwide. This review aimed to summarize and analyze the herbal formulae provided by the guidelines for their pattern identifications (PIs) and compositions of herbs to treat patients with COVID-19. Methods: We searched 7 data sources for eligible traditional medicine guidelines up to March 6, 2020 and found a total of 28 traditional medicine guidelines that provide treatment measures for COVID-19. : Of the 28 guidelines, there were 26 government-issued Chinese guidelines and 2 Korean guidelines. After standardizing the terminology of the PIs and herbal formulae, there were 8 PIs and 23 herbal formulae for the mild stage, 11 PIs and 31 herbal formulae for the moderate stage, 8 PIs and 21 herbal formulae for the severe stage, and 6 PIs and 23 herbal formulae for the recovery stage in the Chinese guidelines. In the Korean guidelines, there were 4 PIs and 15 herbal formulae for the mild stage, 3 PIs and 3 herbal formulae for the severe stage, and 2 PIs and 2 herbal formulae for the recovery stage. In the frequency analysis of herbs, Glycyrrhizae Radix et Rhizoma was found to be the herb with the highest frequency of usage in the Chinese guidelines. Conclusion: This review can be used as guidance for the traditional medicine treatment of COVID-19. Clinical evidence is needed in the future to evaluate the efficacy of traditional medicine. Page 3 of 24 J o u r n a l P r e -p r o o f Ephedrae Herba 5-10g, Armeniacae Semen Amarum 5-10g, Gypsum Fibrosum 30-50g, Forsythiae Fructus 10-20g, Scutellariae Radix 5-10g, Bupleuri Radix 10-15g, Coicis Semen 10-15g, Magnoliae Officinalis Cortex 5-10g, Poria Sclerotium 10-15g, Glycyrrhizae Radix et Rhizoma 5-10g Ephedrae Herba 6g, Armeniacae Semen Amarum 15g, Amomi Tsao-ko Fructus 6g, Arecae Semen 10g, Cicadae Periostracum 10g, Forsythiae Fructus 20g, Atractylodis Rhizoma 10g, Platycodonis Radix 10g, Scutellariae Radix 15g, Coicis Semen 20g, Arctii Semen 15g, Moslae Herba 12g Huo Po Xia Ling Tang* + Yin Qiao San Agastachis Herba 15g, Perillae Folium 15g, Sojae Semen Preparatum 15g, Atractylodis Rhizoma 15g, Magnoliae Officinalis Cortex 10g, Angelicae Decursivae Radix 15g, Bupleuri Radix 15g, Scutellariae Radix 10g, Artemisiae Annuae Herba 20g, Armeniacae Semen Amarum 10g, Osterici seu Notopterygii Radix et Rhizoma 10g, Lonicerae Flos 15g, Forsythiae Fructus 15g Dampness Encumbering the Exterior and Interior Ephedrae Herba 6g, Armeniacae Semen Amarum 9g, Coicis Semen 18g, Amomi Fructus Rotundus 9g, Agastachis Herba 9g, Magnoliae Officinalis Cortex 12g, Pinelliae Rhizoma Praeparatum cum alumine 9g, Poria Sclerotium 12g, Polyporus 9g, Scutellariae Radix 9g, Forsythiae Fructus 12g, Glycyrrhizae Radix et Rhizoma 6g Pathogen Invading the Stomach and Intestines No specific PI Qingfei Paidu Tang Ephedrae Herba 9g, Glycyrrhizae Radix et Rhizoma 6g, Armeniacae Semen Amarum 9g, Gypsum Fibrosum 15~30g, Cinnamomi Ramulus 9g, Alismatis Rhizoma 9g, Polyporus 9g, Atractylodis Macrocephalae Rhizoma 9g, Poria Sclerotium 15g, Bupleuri Radix16g, Scutellariae Radix 6g, Pinelliae Rhizoma 9g, Zingiberis Rhizoma Recens 9g, Asteris Radix 9g, Farfare Flos 9g, Belamcandae Rhizoma 9g, Asari Herba 6g, Dioscoreae Rhizoma 12g, Aurantii Fructus 6g, Citri Unshius Pericarpium 6g, Agastachis Herba 9g
Title: Journal Pre-proof Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines
Answer:
False