input with options: Question: what phase clinical trial new drug application? Would "A full series of trials may incur sizable costs, and the burden of paying for all the necessary people and services is usually borne by the sponsor, which may be a governmental organization or a pharmaceutical , biotechnology or medical device company." be a reasonable answer?
OPTIONS:
- No
- Yes
output: No
Q: Question: when did mass unemployment start?? Would "During periods of recession , an economy usually experiences a relatively high unemployment rate." be a reasonable answer?

OPTIONS:
- No
- Yes

A: No
input: OPTIONS:
- No
- Yes Now, answer this question: Question: what we talkin about band member? Would "Their first two releases, DC Talk and Nu Thang, were of the hip hop genre." be a reasonable answer?
A:
output: No
Question: how much of earth is covered ocean water? Would "Waves on an ocean coast ." be a reasonable answer?

OPTIONS:
- No
- Yes

Answer: No
Problem: OPTIONS:
- No
- Yes
Q: Question: Who holds records for most weeks spent at number one as female artist? Would "This is a comprehensive listing which highlights significant achievements and milestones based upon Billboard magazine 's singles charts, most notably the Billboard Hot 100 ." be a reasonable answer?
Answer: No
Question: where is the valley at in los angeles? Would "Nearly two thirds of the Valley's land area is part of the City of Los Angeles ." be a reasonable answer?

OPTIONS:
- No
- Yes

Answer:
No