TASK DEFINITION: Given an abstract of a paper, generate a title for this paper such that conveys the key focus of the paper.
PROBLEM: Abstract: The concentration of interferon-alpha was measured by a specific two-site immunoradiometric assay in a variety of fluids and tissues collected during human pregnancy. Maternal blood and blood and tissues from non-pregnant adults contained little or no interferon-alpha. Fetal blood, fetal organs, placenta, membranes, amniotic fluid and decidua all contained significant and roughly equivalent amounts ranging from 1.1 to 10 u/ml (or per g of tissue). These findings demonstrate that the fetus and its immediate surroundings are permeated with interferon. It is suggested that this may play a role in regulation of the maternal-fetal graft relation.

SOLUTION: Alpha interferon in human pregnancy.

PROBLEM: Abstract: In a cross-sectional survey of 652 workers in a western red-cedar sawmill, we obtained data on symptoms, pulmonary function, immediate skin reactivity to common allergens, nonspecific bronchial responsiveness, total IgE level, and sensitization to plicatic acid conjugated with human serum albumin as measured by RAST. Dust exposure was estimated by personal and area sampling for total dust during a work shift and cumulative exposure by duration of employment. Seven percent of the workers had an elevated RAST, and 20% had nonspecific bronchial hyperresponsiveness. Elevation in RAST was associated with bronchial hyperresponsiveness. Almost half (46%) of the workers with RAST elevation had bronchial hyperresponsiveness compared to 18% in workers with no RAST elevation. The association was unaffected by total IgE level or by limiting the analysis to workers without respiratory symptoms and was most apparent in younger workers. Bronchial hyperresponsiveness was associated with increased prevalence of respiratory symptoms as well as with lower levels of pulmonary function. The likelihood of bronchial hyperresponsiveness increased with increasing age but was unrelated to the dust-exposure concentration. RAST elevation was unrelated to employment duration or dust exposure and was not associated with an increased prevalence of symptoms or lower levels of pulmonary function independent of bronchial hyperresponsiveness. We conclude that plicatic acid-specific IgE and nonspecific bronchial hyperresponsiveness are associated in western red-cedar workers and that this association may reflect a causal connection.

SOLUTION: Plicatic acid-specific IgE and nonspecific bronchial hyperresponsiveness in western red-cedar workers.

PROBLEM: Abstract: The purpose of the present experiment was to study frequency changes in gastric myoelectric activity of healthy human subjects and the development of symptoms of motion sickness as brought about by vection or illusory self-motion. Fifteen fasted healthy human subjects were seated inside a circular vection drum, the rotation of which produces visual signals of self-motion that are in conflict with vestibular signals (i.e., mismatched sensory input). An electrogastrogram was obtained for three 15-min. periods: baseline, rotation, and after drum rotation stopped. Respiration, symptoms volunteered by subjects, and a continuous measure of intensity of symptoms were recorded. Five subjects showed a continuation of normal 3-cycles/min. activity during drum rotation and reported no symptoms of motion sickness. Ten subjects showed a shift of their dominant gastric frequency from 3 cycles/min. to 4-9 cycles/min. during drum rotation and reported symptoms of motion sickness. Running spectral analysis revealed a close correspondence over time between tachygastria and reports of symptoms of motion sickness.

SOLUTION:
Spectral analysis of tachygastria recorded during motion sickness.