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Yale and New Haven are working to build a medical and biotechnology research hub in the city and Greater New Haven region, and are succeeding to some extent.[citation needed] The city, state and Yale together run Science Park, a large site three blocks northwest of Yale's Science Hill campus. This multi-block site, approximately bordered by Mansfield Street, Division Street, and Shelton Avenue, is the former home of Winchester's and Olin Corporation's 45 large-scale factory buildings. Currently, sections of the site are large-scale parking lots or abandoned structures, but there is also a large remodeled and functioning area of buildings (leased primarily by a private developer) with numerous Yale employees, financial service and biotech companies.

The area of Science Park was originally filled with what?
Answer: 45 large-scale factory buildings
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"Whereas their Majesties have been Graciously Pleased to grant Letters patent to John Lofting of London Merchant for a New Invented Engine for Extinguishing Fires which said Engine have found every great encouragement. The said Patentee hath also projected a Very Useful Engine for starting of beer and other liquors which will deliver from 20 to 30 barrels an hour which are completely fixed with Brass Joints and Screws at Reasonable Rates. Any Person that hath occasion for the said Engines may apply themselves to the Patentee at his house near St Thomas Apostle London or to Mr. Nicholas Wall at the Workshoppe near Saddlers Wells at Islington or to Mr. William Tillcar, Turner, his agent at his house in Woodtree next door to the Sun Tavern London."

What tavern did William Tillcar live adjacent to?
Answer: Sun Tavern
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Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term "having a gene" (e.g., "good genes," "hair colour gene") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.

What does "having a gene" or a "good gene" typically refer to?
Answer:
having a different allele of the gene