In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Q: Question: Acetyl-CoA:
Options: <1> It is synthesized from pyruvate in the eukaryotic cytoplasm. <2> It has a phosphate bond rich in energy. <3> Presents a guanine nucleotide in coenzyme A. <4> Activates pyruvate carboxylase and inhibits pyruvate dehydrogenase. <5> It easily crosses the mitochondrial inner membrane.
A:
4