Quoc: The Great Plague, lasting from 1665 to 1666, was the last major epidemic of the bubonic plague to occur in England. It happened within the centuries-long time period of the Second Pandemic, an extended period of intermittent bubonic plague epidemics which began in Europe in 1347, the first year of the Black Death, an outbreak which included other forms such as pneumonic plague, and lasted until 1750.

Answer this question based on the passage: when did the great plague start and end?
HW Chung: OK, some thoughts:
The relevant information is: The Great Plague, lasting from 1665 to 1666, was the last major epidemic of the bubonic plague to occur in England. The answer is 1665 to 1666.