Question: Affirmed (February 21, 1975 - January 12, 2001) was an American Thoroughbred racehorse who was the eleventh winner of the United States Triple Crown of Thoroughbred Racing. Affirmed was also known for his famous rivalry with Alydar, whom he met ten times, including in all three Triple Crown races. Affirmed was the last horse to win the Triple Crown for a 37-year period, which was ended in 2015 by American Pharoah. Affirmed won fourteen Grade

Alydar was made the 6-5 favorite for Kentucky Derby, with Affirmed the second choice at 9-5 and undefeated Sensitive Prince the third choice at 9-2. At the start of the Kentucky Derby, Sensitive Prince took the early lead as Affirmed ran in third through the early stages, while Alydar stayed far back. Affirmed made a strong move for the lead on the far turn, put away a challenge by Wood Memorial winner Believe It, and held off Alydar's fast-closing charge to win by 1 1/2 lengths. Affirmed now had a 5-2 edge in the series. In the Preakness Stakes, Affirmed set the pace. Alydar made his big move on the far turn, at the same point in the race where Affirmed made his winning move in the Derby. Affirmed held a short lead entering the stretch and held it to defeat Alydar by a neck. Alydar's partisans assumed that the 1 1/2 mile distance of the Belmont, two furlongs longer than the Derby and 5/16 of a mile longer than the Preakness Stakes, would favor Alydar with his finishing style and staying pedigree, and he would deny Affirmed the Triple Crown. Trainer Veitch removed Alydar's blinkers for the Belmont, saying that if Alydar got a better look at Affirmed, maybe he would get by him. In the Belmont, Affirmed led and set a very slow pace, going the first quarter mile in 25 seconds and the half in 50 seconds. Alydar's jockey, Jorge Velasquez, put Alydar close to the pace, and moved alongside Affirmed with more than seven furlongs to go. For more than six furlongs (half the distance of the race), the colts raced neck and neck, pulling away from the rest of the field. Alydar got his nose in front at mid-stretch, but just as Affirmed appeared to tire, Cauthen went to a left-handed whip, something he had never done before in his eight rides on Affirmed. Affirmed won by a nose to become racing's 11th (and last winner for 37 years until American Pharoah won in 2015), Triple Crown winner. After the third slowest start in Belmont Stakes history, they raced the fastest last mile in Belmont Stakes history, 3/4 in 1:14, the mile in 1:37 2/5 and finished in 2:26 4/5. It was, at the time, the third fastest Belmont ever, behind Secretariat and Gallant Man. His Triple Crown win set two records: the shortest and longest gaps between the previous and next Triple Crown winners. Affirmed's win in 1978 was the first time the Triple Crown had been won in consecutive years (Seattle Slew won in 1977). Affirmed's win also marked the start of the longest gap until the next Triple Crown winner, with American Pharoah's win on June 6, 2015 occurring 37 years later.

Using a quote from the above article, answer the following question: Who did he beat in the preakness
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Answer: Affirmed held a short lead entering the stretch and held it to defeat Alydar by a neck.

Problem: Camillo Golgi (Italian: [ka'millo 'goldZi]; 7 July 1843 - 21 January 1926) was an Italian physician and pathologist known for his works on the central nervous system. He studied medicine at the University of Pavia (where he later spent most of his professional career) between 1860 and 1868 under the tutelage of Cesare Lombroso. Inspired by pathologist Giulio Bizzozero, he pursued research in nervous system. His discovery of a staining technique called black reaction (sometimes called Golgi's method or Golgi's staining in his honour) in 1873 was a major breakthrough in neuroscience.

Central nervous system was difficult to study during Golgi's time because the cells were hard to identify. The available tissue staining techniques were useless for studying nervous tissue. While working as chief medical officer at the Hospital of the Chronically Ill, he experimented with metal impregnation of nervous tissue, using mainly silver (silver staining). In the early 1873, he discovered a method of staining nervous tissue that would stain a limited number of cells at random in their entirety. He first treated the tissue with potassium dichromate to harden it, and then with silver nitrate. Under microscope, the outline of the neuron became distinct from the surrounding tissue and cells. The silver chromate precipitate, as a reaction product, only selective stains some cellular components randomly, sparing other cell parts. The silver chromate particles create a stark black deposit on the soma (nerve cell body) as well as on the axon and all dendrites, providing an exceedingly clear and well-contrasted picture of neuron against a yellow background. This makes it easier to trace the structure of the nerve cells in the brain for the first time. Since cells are selective stained in black, he called the process la reazione nera ("the black reaction"), but today it is called Golgi's method or the Golgi stain. On 16 February 1873, he wrote to his friend Niccolo Manfredi: I am delighted that I have found a new reaction to demonstrate, even to the blind, the structure of the interstitial stroma of the cerebral cortex. His discovery was published in the Gazzeta Medica Italiani on 2 August 1873.

what year did this begin

Answer with quotes:
In the early 1873, he discovered a method