TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does presence of the full-length KIR2DS4 gene reduce the chance of rheumatoid arthritis patients to respond to methotrexate treatment?
Answer: Our results suggest that the response of RA patients with medium ESR values to MTX treatment may be dependent on the full-length KIR2DS4 gene.

SOLUTION: yes

PROBLEM: Question: Do dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer?
Answer: Combination therapy of radiation with nafamostat mesilate exerts enhanced anti-tumor effect against human pancreatic cancer.

SOLUTION: yes

PROBLEM: Question: Is the paraoxonase-1 pathway a major bioactivation pathway of clopidogrel in vitro?
Answer: This in vitro study shows that the contribution of PON1 to clopidogrel metabolism is limited at clinically relevant concentrations. Moreover, CYP2C19, CYP2B6 and CYP3A play important roles in the bioactivation of clopidogrel.

SOLUTION:
no