Premise:
"I do shake hands, [but] I think it's a terrible custom."
Hypothesis: I do not shake hands.

no

Premise:
"uh-huh i mean it's real funny because if you you know it seems like when you exercise and expend the energy that you'd be tired but it's the other way around"
Hypothesis: It's funny because you don't feel tired even though you're using energy.

yes

Premise:
"uh being a former drug user"
Hypothesis: Drugs have never been used.
no