Given a passage classify if the passage has a definite objective/aim/goal or not. Output '1' if the passage has a defininte objective/aim/goal and output '0' if the passage does not have a definite objective/aim/goal.

Recent studies have demonstrated that the neural precursor cell expressed, developmentally downregulated 4-like (Nedd4L) gene plays a role in the progression of various cancers. However, reports describing Nedd4L expression in ovarian cancer tissues are limited.', 'A cohort (n=117) of archival formalin-fixed, paraffin embedded resected normal ovarian epithelial tissues (n=10), benign ovarian epithelial tumor tissues (n=10), serous borderline ovarian epithelial tumor tissues (n=14), mucous borderline ovarian epithelial tumor tissues (n=11), and invasive ovarian epithelial cancer tissues (n=72) were assessed for Nedd4L protein expression using immunohistochemistry.', 'Nedd4L protein expression was significantly decreased in invasive ovarian epithelial cancer tissues compared to non-cancer tissues (P<0.05). Decreased Nedd4L protein expression correlated with clinical stage, pathological grade, lymph node metastasis and survival (P<0.05).
1