Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

[EX Q]: The mass remains the same does burning matter affect its mass.
[EX A]: How does burning matter affect its mass?

[EX Q]: Multiple genes mutations is usually necessary to develop cancer.
[EX A]: What is usually necessary to develop cancer?

[EX Q]: Iconic compounds have a net neutral charge.
[EX A]:
What kind of charge do iconic compounds have?