Definition: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
Input: Paragraph: Wenxiang diagram is a new two-dimensional representation that characterizes the disposition of hydrophobic and hydrophilic residues in a-helices. In this research, the hydrophobic and hydrophilic residues of two leucine zipper coiled-coil (LZCC) structural proteins, cGKIa 1 A 59 and MBS CT35 are dispositioned on the wenxiang diagrams according to heptad repeat pattern (abcdefg) n , respectively. Their wenxiang diagrams clearly demonstrate that the residues with same repeat letters are laid on same side of the spiral diagrams, where most hydrophobic residues are positioned at a and d, and most hydrophilic residues are localized on b, c, e, f and g polar position regions. The wenxiang diagrams of a dimetric LZCC can be represented by the combination of two monomeric wenxiang diagrams, and the wenxiang diagrams of the two LZCC (tetramer) complex structures can also be assembled by using two pairs of their wenxiang diagrams. Furthermore, by comparing the wenxiang diagrams of cGKIa 1 A 59 and MBS CT35 , the interaction between cGKIa 1 A 59 and MBS CT35 is suggested to be weaker. By analyzing the wenxiang diagram of the cGKIa 1 A 59. AMBS CT42 complex structure, most affected residues of cGKIa 1 A 59 by the interaction with MBS CT42 are proposed at positions d, a, e and g of the LZCC structure. These findings are consistent with our previous NMR results. Incorporating NMR spectroscopy, the wenxiang diagrams of LZCC structures may provide novel insights into the interaction mechanisms between dimeric, trimeric, tetrameric coiled-coil structures.
Title: The disposition of the LZCC protein residues in wenxiang diagram provides new insights into the protein-protein interaction mechanism
Output:
True