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Vaccines rely on immune modulation or augmentation. Vaccination either excites or reinforces the immune competence of a host to ward off infection, leading to the activation of macrophages, the production of antibodies, inflammation, and other classic immune reactions. Antibacterial vaccines have been responsible for a drastic reduction in global bacterial diseases. Vaccines made from attenuated whole cells or lysates have been replaced largely by less reactogenic, cell-free vaccines consisting of purified components, including capsular polysaccharides and their conjugates, to protein carriers, as well as inactivated toxins (toxoids) and proteins.
What do polysaccharides need to work?
A: unanswerable

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San Diego is served by the San Diego Trolley light rail system, by the SDMTS bus system, and by Coaster and Amtrak Pacific Surfliner commuter rail; northern San Diego county is also served by the Sprinter light rail line. The Trolley primarily serves downtown and surrounding urban communities, Mission Valley, east county, and coastal south bay. A planned Mid-Coast extension of the Trolley will operate from Old Town to University City and the University of California, San Diego along the I-5 Freeway, with planned operation by 2018. The Amtrak and Coaster trains currently run along the coastline and connect San Diego with Los Angeles, Orange County, Riverside, San Bernardino, and Ventura via Metrolink and the Pacific Surfliner. There are two Amtrak stations in San Diego, in Old Town and the Santa Fe Depot downtown. San Diego transit information about public transportation and commuting is available on the Web and by dialing "511" from any phone in the area.
Where do the Amtrak and Coaster trains primarily run?
A: along the coastline

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A new phase in neoclassical design was inaugurated by Robert and James Adam, who travelled in Italy and Dalmatia in the 1750s, observing the ruins of the classical world. On their return to Britain, they published a book entitled The Works in Architecture in installments between 1773 and 1779. This book of engraved designs made the Adam repertory available throughout Europe. The Adam brothers aimed to simplify the rococo and baroque styles which had been fashionable in the preceding decades, to bring what they felt to be a lighter and more elegant feel to Georgian houses. The Works in Architecture illustrated the main buildings the Adam brothers had worked on and crucially documented the interiors, furniture and fittings, designed by the Adams.
Where were the inspirations for the new phase of neoclassicism centered?
A: Italy and Dalmatia

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Despite the initial negative press, several websites have given the system very good reviews mostly regarding its hardware. CNET United Kingdom praised the system saying, "the PS3 is a versatile and impressive piece of home-entertainment equipment that lives up to the hype [...] the PS3 is well worth its hefty price tag." CNET awarded it a score of 8.8 out of 10 and voted it as its number one "must-have" gadget, praising its robust graphical capabilities and stylish exterior design while criticizing its limited selection of available games. In addition, both Home Theater Magazine and Ultimate AV have given the system's Blu-ray playback very favorable reviews, stating that the quality of playback exceeds that of many current standalone Blu-ray Disc players.
What website said the PlayStation 3 "lives up to the hype"?
A:
CNET United Kingdom