Actor Philip Seymour Hoffman, who was found dead February 2 on the bathroom floor of his New York apartment with a syringe in his left arm, died of acute mixed drug intoxication, including heroin, cocaine, benzodiazepines and amphetamine, the New York medical examiner's office said Friday.

The manner of death was ruled an accident, the medical examiner's office said in a statement.

Dr. Sanjay Gupta, CNN's chief medical correspondent, said that as addicts take mixtures of drugs more chronically, they may not necessarily feel the effects of the narcotics, which still suppress the respiratory system.

"They're not feeling it, but it's still having an impact on their ability to breathe, and that's the real problem," he said. "It's called stacking. You can stack the same drug too close together, or you can start to stack other drugs, one on top of the other. That's how people get into trouble. They do call it accidental death as well."

Police found nearly 50 envelopes branded "Ace of Spades" filled with what they believe was heroin in the actor's Manhattan apartment, two law enforcement sources familiar with the inquiry said.

Used syringes, prescription drugs and empty bags that authorities suspect were used to hold heroin also were found in the apartment where Hoffman, 46, was found dead, sources said.

He was expected to pick up his children that day but didn't show up, the official said. Playwright David Katz and another person went to the apartment and found him dead, the official said.

Police officers found him in a T-shirt and shorts with his eyeglasses still on his head. What are the answers to this following set of questions: 1. What state medical examiner's office handled the actor's death?
2. What is the actor's first name?
3. And last name?
4. And middle name?
5. Was the actor's death judged to be an accident?
6. Through what means did the medical examiner's office release this information?
7. What was the brand on the envelopes found/
8. What drug was in the envelope?
9. Was Hoffman found dead in a house?
10. In what city was his apartment?
11. How old was he at the time of his death?
12. What is the last name of CNN's medical correspondent?
13. And his first name?
14. What is the last name of the playwright who found his body?
15. Was someone else with Katz?
16. What was Hoffman wearing when found?
17. What did he have on his head?
18. What persons were Hoffman supposed to pick up that day?
19. In which arm of Hoffman's was a syringe found?
Answer: 1. New York
2. Philip
3. Hoffman
4. Seymour
5. yes
6. a statement.
7. "Ace of Spades"
8. heroin
9. no
10. New York
11. 46
12. Gupta
13. Sanjay
14. David Katz
15. yes
16. in a tee shirt and shorts
17. his eyeglasses
18. his children
19. the left

(CNN) -- Katy Perry is officially the queen of Twitter.

The singer has reached more than 50 million followers on the social media site, making her the most followed person in the universe.

Perry took the milestone in stride. "Oh yeah AND we grew to 50 million Katycats! Eh, regular day at the office," she tweeted (of course).

Not that Perry doesn't have competition hot on her heels.

Justin Bieber has about 49.4 million "beliebers" hanging on his every 140-character submission, while President Barack Obama has around 41.2 million followers. Lady Gaga has just over 41 million "little monsters."

The video site YouTube, Taylor Swift, Britney Spears, Rihanna, Instagram, and Justin Timberlake round out the rest of the top 10 most-followed Twitter accounts.

Perry snagged the Twitter throne from Bieber in November. He, in turn, had earlier toppled Gaga, who for two years was the most followed person. In October she told USA Today that felt felt like she had "learned how to tame that social media dragon."

What are the answers to this following set of questions: 1. how many followers does Katy have?
2. what about Beiber?
3. when did Katy earn the top spot?
4. who was top before Bieber?
5. what did she say about it?
6. what does Katy call her fans?
7. what does Justin call his?
8. how many characters can a tweet be?
9. someone else in the top 10?
10. are all the accounts people?
11. what does gaga call her fans?
12. any presidents in the top?
Answer: 1. more than 50 million followers
2. about 49.4 million
3. November
4. Gaga
5. felt like she had "learned how to tame that social media dragon."
6. Katycats
7. beliebers
8. 140-character
9. The video site YouTube, Taylor Swift, Britney Spears, Rihanna, Instagram, and Justin Timberlake
10. No
11. little monsters
12. President Barack Obama

The War of 1812 (18121815) was a conflict fought between the United States, the United Kingdom, and their respective allies. Historians in Britain often see it as a minor theater of the Napoleonic Wars; in the United States and Canada, it is seen as a war in its own right.

Since the outbreak of war with Napoleonic France, Britain had enforced a naval blockade to choke off neutral trade to France, which the United States contested as illegal under international law. To man the blockade, Britain impressed American merchant sailors into the Royal Navy. Incidents such as the "ChesapeakeLeopard" Affair inflamed anti-British sentiment. In 1811, the British were in turn outraged by the "Little Belt" Affair, in which 11 British sailors died. British political support for a Native American buffer state, which conducted raids on American settlers on the frontier, hindered American expansion. On June 18, 1812, President James Madison, after receiving heavy pressure from the War Hawks in Congress, signed the American declaration of war into law. Senior figures such as Lord Liverpool and Lord Castlereagh believed it to have been an opportunistic ploy to annex Canada while Britain was fighting a war with France. The view was shared in much of New England. What are the answers to this following set of questions: 1. Who signed a declaration for America?
2. When did he do it?
3. What specific declaration was it?
4. Which war did this begin?
5. Who was it between?
6. Did the Brits view it as part of a larger engagement?
7. Which one?
8. What other country was a major player in that conflict?
9. Which country had a naval blockade imposed on them?
10. Did the US believe this was legal?
11. What did the Brits do to keep the blockade running?
12. How long did the American war last?
13. Did people believe this conflict was an attempt to add more territory to the US?
14. Which people in particular?
15. Was this opinion common in much of the South?
Answer:
1. James Madison
2. 1812
3. American declaration of war
4. The War of 1812
5. he United States, the United Kingdom, and their respective allies
6. Yes
7. the Napoleonic Wars
8. Canada
9. France
10. No
11. impressed American merchant sailors into the Royal Navy
12. 3 years
13. Yes
14. Senior figures such as Lord Liverpool and Lord Castlereagh
15. No