IN: Yelberton Abraham Tittle Jr. (October 24, 1926 - October 8, 2017), better known as Y. A. Tittle, was a professional American football quarterback. He played in the National Football League (NFL) for the San Francisco 49ers, New York Giants, and Baltimore Colts, after spending two seasons with the Colts in the All-America Football Conference (AAFC). Known for his competitiveness, leadership, and striking profile, Tittle was the centerpiece of several prolific offenses throughout his seventeen-year professional career from 1948 to 1964. Tittle played college football for Louisiana State University, where he was a two-time All-Southeastern Conference (SEC) quarterback for the LSU Tigers football team.

At the time of his retirement, Tittle held the following NFL records: Tittle was the fourth player to throw seven touchdown passes in a game, when he did so in 1962 against the Redskins. He followed Sid Luckman (1943), Adrian Burk (1954), and George Blanda (1961). The feat has since been equaled by four more players: Joe Kapp (1969), Peyton Manning (2013), Nick Foles (2013), and Drew Brees (2015). Tittle, Manning and Foles did it without an interception. His 36 touchdown passes in 1963 set a record which stood for over two decades until it was surpassed by Dan Marino in 1984; as of 2016 it remains a Giants franchise record. Despite record statistics and three straight championship game appearances, Tittle was never able to deliver a title to his team. His record as a starter in postseason games was 0-4. He threw four touchdown passes against 14 interceptions and had a passer rating of 33.8 in his postseason career, far below his regular season passer rating of 74.3. Seth Wickersham, writing for ESPN The Magazine in 2014, noted the dichotomy in the 1960s between two of New York's major sports franchises: "... Gifford, Huff and Tittle, a team of Hall of Famers known for losing championships as their peers on the Yankees--with whom they shared a stadium, a city, and many rounds of drinks--became renowned for winning them." The Giants struggled after Tittle's retirement, posting only two winning seasons from 1964 to 1980. He made seven Pro Bowls, four first-team All-Pro teams, and four times was named the NFL's Most Valuable Player or Player of the Year: in 1957 and 1962 by the UPI; in 1961 by the NEA; and in 1963 by the AP and NEA. In a sports column in 1963, George Strickler for the Chicago Tribune remarked Tittle had "broken records that at one time appeared unassailable and he has been the hero of more second half rallies than Napoleon and the Harlem Globetrotters." He was featured on four Sports Illustrated covers: three during his playing career and one shortly after retirement. His first was with the 49ers in 1954. With the Giants, he graced covers in November 1961, and he was on the season preview issue for 1964; a two-page fold-out photo from the 1963 title game. Tittle was on a fourth cover in August 1965. The trade of Tittle for Lou Cordileone is seen as one of the worst trades in 49ers history; it is considered one of the best trades in Giants franchise history. Cordileone played just one season in San Francisco.

Are there any other interesting aspects about this article?

OUT: " He was featured on four Sports Illustrated covers: three during his playing career and one shortly after retirement.

IN: Tu Youyou (Chinese: Tu You You ; pinyin: Tu Youyou; born 30 December 1930) is a Chinese pharmaceutical chemist and educator. She is best known for discovering artemisinin (also known as qinghaosu) and dihydroartemisinin, used to treat malaria, which has saved millions of lives.

Tu Youyou carried on her work in the 1960s and 70s during China's Cultural Revolution, when scientists were denigrated as one of the nine black categories in society according to Maoist theory (or possibly that of the Gang of Four). In 1967, during the Vietnam War, Ho Chi Minh, the leader of North Vietnam, which was at war against South Vietnam and the United States, asked Chinese Premier Zhou Enlai for help in developing a malaria treatment for his soldiers trooping down the Ho Chi Minh trail, where a majority came down with a form of malaria which is resistant to chloroquine. Because malaria was also a major cause of death in China's southern provinces including Hainan, Yunnan, Guangxi, and Guangdong, Zhou Enlai convinced Mao Zedong to set up a secret drug discovery project, named Project 523 after its starting date, 23 May 1967. Upon joining the project unit, Tu was initially sent to Hainan where she studied patients who had been infected with the disease. During the time she spent there, her husband was banished to the countryside, meaning that her daughter had to be entrusted to a nursery in Beijing. Scientists worldwide had screened over 240,000 compounds without success. In 1969, Tu Youyou, then 39 years old, had an idea of screening Chinese herbs. She first investigated the Chinese medical classics in history, visiting practitioners of traditional Chinese medicine all over the country on her own. She gathered her findings in a notebook called A Collection of Single Practical Prescriptions for Anti-Malaria. Her notebook summarized 640 prescriptions. Her team also screened over 2,000 traditional Chinese recipes and made 380 herbal extracts, which were tested on mice. One compound was effective, sweet wormwood (Artemisia annua), which was used for "intermittent fevers," a hallmark of malaria. As Tu also presented at the project seminar, its preparation was described in a 1,600-year-old text, in a recipe titled, "Emergency Prescriptions Kept Up One's Sleeve". At first, it didn't work, because they extracted it with traditional boiling water. Tu Youyou discovered that a low-temperature extraction process could be used to isolate an effective antimalarial substance from the plant; Tu says she was influenced by a traditional Chinese herbal medicine source, The Handbook of Prescriptions for Emergency Treatments, written in 340 by Ge Hong, which states that this herb should be steeped in cold water. This book contained the useful reference to the herb: "A handful of qinghao immersed with two litres of water, wring out the juice and drink it all." After rereading the recipe, Tu realised the hot water had already damaged the active ingredient in the plant; therefore she proposed a method using low-temperature ether to extract the effective compound instead. The animal tests showed it was completely effective in mice and monkeys. Furthermore, Tu volunteered to be the first human subject. "As head of this research group, I had the responsibility" she said. It was safe, so she conducted successful clinical trials with human patients. Her work was published anonymously in 1977. In 1981, she presented the findings relating to artemisinin at a meeting with the World Health Organization.

What did she do with her findings

OUT:
gathered her findings in a notebook called A Collection of Single Practical Prescriptions for Anti-Malaria.