In this task, you are given a passage which has a question and the context. You have to generate an answer to the question based on the information present in the context.

Context: Cardiac malfunction is a common complication in sepsis and significantly increases the mortality of patients in septic shock. However, no studies have examined whether andrographolide (And) reduces LPS-induced myocardial malfunction.', 'Left ventricular systolic and diastolic functions were examined using echocardiography. TNF- and IL-1 protein levels were detected by an enzyme-linked immunosorbent assay (ELISA). NO oxidation products were determined using Griess reagent. Protein expression levels of inhibitors of NF-B (IB) and phospho-IB were determined via Western blot. Oxidative injury was determined by measuring myocardial lipid peroxidation and superoxide dismutase activity. Cardiac apoptosis was examined by terminal deoxynucleotidyl transferase-mediated dUTP nickend-labeling (TUNEL) and cardiac caspase 3/7 activity.', 'And blunted LPS-induced myocardial malfunctions in mice. LPS induced TNF-, IL-1, and NO production as well as I-B phosphorylation. Cardiac apoptosis was attenuated via incubation with And, but the extent of oxidative injury remained unaffected.\Question: Does andrographolide attenuate LPS-Induced Cardiac Malfunctions Through Inhibition of IB Phosphorylation and Apoptosis in Mice?
And prevents LPS-induced cardiac malfunctions in mice by inhibiting TNF-, IL-1, and NO production, IB phosphorylation, and cardiac apoptosis, indicating that And may be a potential agent for preventing myocardial malfunction during sepsis.