Input: Article: Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or developing formulations. Often, collaborative agreements between research organizations and large pharmaceutical companies are formed to explore the potential of new drug substances. More recently, multi-nationals are increasingly relying on contract research organizations to manage drug development.

Now answer this question: What type of integration do smaller organizations do?

Output: a specific aspect

Input: Article: After Alexander the Great's ventures in the Persian Empire, Hellenistic kingdoms were established throughout south-west Asia (Seleucid Empire, Kingdom of Pergamon), north-east Africa (Ptolemaic Kingdom) and South Asia (Greco-Bactrian Kingdom, Indo-Greek Kingdom). This resulted in the export of Greek culture and language to these new realms through Greco-Macedonian colonization, spanning as far as modern-day Pakistan. Equally, however, these new kingdoms were influenced by the indigenous cultures, adopting local practices where beneficial, necessary, or convenient. Hellenistic culture thus represents a fusion of the Ancient Greek world with that of the Near East, Middle East, and Southwest Asia, and a departure from earlier Greek attitudes towards "barbarian" cultures. The Hellenistic period was characterized by a new wave of Greek colonization (as distinguished from that occurring in the 8th6th centuries BC) which established Greek cities and kingdoms in Asia and Africa. Those new cities were composed of Greek colonists who came from different parts of the Greek world, and not, as before, from a specific "mother city". The main cultural centers expanded from mainland Greece to Pergamon, Rhodes, and new Greek colonies such as Seleucia, Antioch, Alexandria and Ai-Khanoum. This mixture of Greek-speakers gave birth to a common Attic-based dialect, known as Koine Greek, which became the lingua franca through the Hellenistic world.

Now answer this question: Alexander the Great was the emperor of what?

Output: Persian Empire

Input: Article: The Pacific War saw the Allied powers pitted against the Empire of Japan, the latter briefly aided by Thailand and to a much lesser extent by its Axis allies, Germany and Italy. The war culminated in the atomic bombings of Hiroshima and Nagasaki, and other large aerial bomb attacks by the United States Army Air Forces, accompanied by the Soviet invasion of Manchuria on 8 August 1945, resulting in the Japanese announcement of intent to surrender on 15 August 1945. The formal and official surrender of Japan took place aboard the battleship USS Missouri in Tokyo Bay on 2 September 1945. Following its defeat, Japan's Shinto Emperor stepped down as the divine leader through the Shinto Directive, because the Allied Powers believed this was the major political cause of Japan's military aggression and deconstruction process soon took place to install a new liberal-democratic constitution to the Japanese public as the current Constitution of Japan.

Now answer this question: When did Japan surrender?

Output:
2 September 1945