Given a passage with a context and an answer, construct a question on the basis of the information present in the passage. Construct the question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) it answer uses text phrases from the passage. Avoid creating questions that (i) can't be answered correctly without actually understanding the passage and (ii) uses the same words or phrases given in the passage.
Q: Context: Behcet's disease is a multisystem disease of unknown etiology. Caspase-9 is responsible for initiating the caspase activation cascade during apoptosis. The aim of this study was to examine caspase-9 expression in both endothelial and perivascular infiltrates of patients with active Behcet's disease.", "Fifteen patients with active Behcet's disease, attending the First Dermatology Department, Ankara Numune Hospital, Ankara, Turkey between June 2003 and December 2005, were included in the study. Oral biopsy specimens from nine healthy volunteers were taken as the healthy control group, and skin biopsies from 18 psoriasis patients were used as the inflammatory control group. The specimens were examined with caspase-9 primary antibody. Statistical analyses were performed using SPSS 11.5.", "The mean caspase-9-positive endothelial cell counts were 7.17 +/- 2.45 in active Behcet's disease, 4.81 +/- 0.76 in healthy controls, and 4.35 +/- 1.34 in inflammatory controls. The difference between Behcet's disease and healthy controls was statistically significant, with increased endothelial staining in active Behcet's disease (P = 0.049). The difference between Behcet's disease and inflammatory controls was also statistically significant; the rate of staining was higher in Behcet's disease (P = 0.006). The mean caspase-9-positive dermal perivascular cell counts were 5.15 +/- 2.32 in Behcet's disease, 3.32 +/- 0.82 in healthy controls, and 5.54 +/- 4.95 in inflammatory controls. These values did not show any statistically significant difference (P = 0.407).
Answer: Endothelial cells are one of the key cells in Behcet's disease, and our findings support the role of endothelial cells in the etiopathogenesis of Behcet's disease.
A:
Is caspase-9 expression increased in endothelial cells of active Behcet 's disease patients?