In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: Question linked to image no. 5 A 41-year-old man referred for presenting for more than 5 years bilateral alternating gluteal pain predominantly nocturnal, which interferes with sleep and relieves with mobilization. It is accompanied by stiffness for more than 1 hour after inactivity. Denies pain, swelling or deformity to another level. It provides elementary analytics without alterations except PCR 11.5 mg / dl (N <5) and the attached radiograph. The objective radiological alteration and the most probable diagnosis would be:
Options: <1> Fracture of Looser- Osteomalacia. <2> Bilateral sacroiliitis - Ankylosing spondylitis. <3> Coexistence of lytic and blastic lesions Paget's disease. <4> Blastic lesions - Prostatic adenocarcinoma with bone metastases. <5> Osteosclerosis - Lymphoma.
[A]: 2

[Q]: Question: Of the following reaction mechanisms, in which there is an inversion of the configuration from the reactant to the product of the reaction ?:
Options: <1> Bimolecular nucleophilic substitution (SN2). <2> Unimolecular elimination (E1). <3> Unimolecular nucleophilic substitution (SN1). <4> Addition Markovnikov. <5> Addition anti-Markovnikov.
[A]: 1

[Q]: Question: In relation to osteoarthritis, what statement is correct?
Options: <1> There is a close correlation between the radiological findings and the symptomatology of the patients. <2> The symptomatic involvement of the hip is much more frequent than the involvement of the knee. <3> Obesity has not been shown to be a risk factor for its development. <4> The presence of a high sedimentation rate strongly supports the diagnosis. <5> Morning stiffness usually lasts less than 30 minutes.
[A]:
5