Instructions: Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
Input: Abstract: Fifteen neutropenic febrile episodes occurred in 29 patients undergoing chemotherapy for malignant germ cell tumors of the ovary. Vincristine, actinomycin-D, and cyclophosphamide were used in 24 patients; cis-diamminedichloroplatinum, vinblastine, and bleomycin in three; and both regimens in two. All 15 patients were treated with antibiotic combinations (gentamicin and clindamycin in 12 cases), usually until neutropenia resolved. The mean nadir total granulocyte count was 123/mm3. There was no septicemia or drug-related deaths. With reduction in chemotherapy dosage, 87% of patients tolerated subsequent courses. The survival rates in this disease are excellent, although toxicity is substantial from both regimens. These neutropenic febrile episodes can be managed successfully without interrupting chemotherapy.
Which is the apt title for the abstract? option1: Neutropenia and fever in patients undergoing combination chemotherapy for malignant germ cell tumors of the ovary. option2: Cadaveric study comparing the stability of upper distraction hooks used in Harrington instrumentation.
Output:
Neutropenia and fever in patients undergoing combination chemotherapy for malignant germ cell tumors of the ovary.