Input: History of India
From the 8th to the 10th century, three dynasties contested for control of northern India: the Gurjara Pratiharas of Malwa, the Palas of Bengal, and the Rashtrakutas of the Deccan. The Sena dynasty would later assume control of the Pala Empire, and the Gurjara Pratiharas fragmented into various states. These were the first of the Rajput states. The first recorded Rajput kingdoms emerged in Rajasthan in the 6th century, and small Rajput dynasties later ruled much of northern India. One Gurjar Rajput of the Chauhan clan, Prithvi Raj Chauhan, was known for bloody conflicts against the advancing Turkic sultanates. The Chola empire emerged as a major power during the reign of Raja Raja Chola I and Rajendra Chola I who successfully invaded parts of Southeast Asia and Sri Lanka in the 11th century. Lalitaditya Muktapida (r. 724 CE760 CE) was an emperor of the Kashmiri Karkota dynasty, which exercised influence in northwestern India from 625 CE until 1003, and was followed by Lohara dynasty. He is known primarily for his successful battles against the Muslim and Tibetan advances into Kashmiri-dominated regions. Kalhana in his Rajatarangini credits king Lalitaditya with leading an aggressive military campaign in Northern India and Central Asia. He broke into the Uttarapatha and defeated the rebellious tribes of the Kambojas, Tukharas (Turks in Turkmenistan and Tocharians in Badakhshan), Bhautas (Tibetans in Baltistan and Tibet) and Daradas (Dards). His campaign then led him to subjugate the kingdoms of Pragjyotisha, Strirajya and the Uttarakurus. The Shahi dynasty ruled portions of eastern Afghanistan, northern Pakistan, and Kashmir from the mid-7th century to the early 11th century.

When did the first Rajput kingdoms emerge in India?
Output: 6th century

Input: Pharmaceutical industry
In contrast to this viewpoint, an article and associated editorial in the New England Journal of Medicine in May 2015 emphasized the importance of pharmaceutical industry-physician interactions for the development of novel treatments, and argued that moral outrage over industry malfeasance had unjustifiably led many to overemphasize the problems created by financial conflicts of interest. The article noted that major healthcare organizations such as National Center for Advancing Translational Sciences of the National Institutes of Health, the President's Council of Advisors on Science and Technology, the World Economic Forum, the Gates Foundation, the Wellcome Trust, and the Food and Drug Administration had encouraged greater interactions between physicians and industry in order to bring greater benefits to patients.

When was the editorial published?
Output: May 2015

Input: New York City
Christianity (59%), particularly Catholicism (33%), was the most prevalently practiced religion in New York as of 2014, followed by Judaism, with approximately 1.1 million Jews in New York City, over half living in Brooklyn. Islam ranks third in New York City, with official estimates ranging between 600,000 and 1,000,000 observers and including 10% of the city's public schoolchildren, followed by Hinduism, Buddhism, and a variety of other religions, as well as atheism. In 2014, 24% self-identified with no organized religious affiliation.

What borough has the largest population of Jewish people?
Output: Brooklyn

Input: Circadian rhythm
The central oscillator generates a self-sustaining rhythm and is driven by two interacting feedback loops that are active at different times of day. The morning loop consists of CCA1 (Circadian and Clock-Associated 1) and LHY (Late Elongated Hypocotyl), which encode closely related MYB transcription factors that regulate circadian rhythms in Arabidopsis, as well as PRR 7 and 9 (Pseudo-Response Regulators.) The evening loop consists of GI (Gigantea) and ELF4, both involved in regulation of flowering time genes. When CCA1 and LHY are overexpressed (under constant light or dark conditions), plants become arrhythmic, and mRNA signals reduce, contributing to a negative feedback loop. Gene expression of CCA1 and LHY oscillates and peaks in the early morning, whereas TOC1 gene expression oscillates and peaks in the early evening. While it was previously hypothesised that these three genes model a negative feedback loop in which over-expressed CCA1 and LHY repress TOC1 and over-expressed TOC1 is a positive regulator of CCA1 and LHY, it was shown in 2012 by Andrew Millar and others that TOC1 in fact serves as a repressor not only of CCA1, LHY, and PRR7 and 9 in the morning loop but also of GI and ELF4 in the evening loop. This finding and further computational modeling of TOC1 gene functions and interactions suggest a reframing of the plant circadian clock as a triple negative-component repressilator model rather than the positive/negative-element feedback loop characterizing the clock in mammals.

What produces a self-sustaining rhythm?
Output:
central oscillator