Q: Brad and Henry were two old friends in their 70's. Brad had very high levels of cholesterol, while Henry was healthier and had normal levels of cholesterol. Which friend takes a drug that removes cholesterol from plasma? Hint: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem.
A: Brad

Question: As an economist Dan is interested in economies of South America. He has extensively studied two countries, Venezuela and Bolivia. His conclusion is Venezuela's economic policy had lead to capital flight. But Bolivia is a completely different story. Their economic policy did not lead to capital flight. In which country investors would retain confidence, Venezuela or Bolivia? Hint: Capital flight, in economics, occurs when assets or money rapidly flow out of a country, due to an event of economic consequence. Such events could be an increase in taxes on capital or capital holders or the government of the country defaulting on its debt that disturbs investors and causes them to lower their valuation of the assets in that country, or otherwise to lose confidence in its economic strength. This leads to a disappearance of wealth, and is usually accompanied by a sharp drop in the exchange rate of the affected countrydepreciation in a variable exchange rate regime, or a forced devaluation in a fixed exchange rate regime. This fall is particularly damaging when the capital belongs to the people of the affected country, because not only are the citizens now burdened by the loss in the economy and devaluation of their currency, but probably also, their assets have lost much of their nominal value. This leads to dramatic decreases in the purchasing power of the country's assets and makes it increasingly expensive to import goods and acquire any form of foreign facilities, e.g. medical facilities.
Answer: Bolivia

[Q]: China used alternative fuels to generate electricity, while Mongolia burned lots of fossil fuels. There were frequent debates between the two countries on this matter. Which country released more anthropogenic emissions? Hint: Carbon dioxide is the most significant long-lived greenhouse gas in Earth's atmosphere. Since the Industrial Revolution anthropogenic emissions primarily from use of fossil fuels and deforestation have rapidly increased its concentration in the atmosphere, leading to global warming. Carbon dioxide also causes ocean acidification because it dissolves in water to form carbonic acid.
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[A]: Mongolia

input: Please answer the following: Two old friends Mary and Ann lived thousands of miles away. Mary lived on the Big Island of Hawaii, while Ann lived in Boston. Mary visited Boston, while Ann has never been to Hawaii. Which friend visited the Kilauea volcano on Hawaii? Hint: The Hawaiian Islands ( Figure above ) are in the central Pacific Ocean. The islands are volcanoes that increase in age from southeast to northwest. The youngest island is the Big Island of Hawaii at the southeast end of the chain. The volcanoes get older through Maui, Kahoolawe, Lanai, Molokai, Oahu, Kauai, and Niihau Islands through the northwest. The Kilauea volcano on Hawaii has been erupting almost continuously since 1983. There are also eruptions at an underwater volcano called Loihi seamount. Loihi is the youngest volcano. Hawaii is a fantastic place to see volcanic eruptions and features.
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output: Mary

Please answer this: Two bakeries were famous in town for their angel food cakes. Tom's was a small bakery with various small ovens, took small orders and did some catering. Bill's bakery was large and produced angel food cake commercially, in vast quantities. Which bakery used a small deck oven to bake angel food cakes? Hint: In a bakery, angel food cakes could be baked in a rack oven, revolving oven, convention oven, or small deck oven. A commercial bakery may use a tunnel or traveling oven.[7] When the cake has finished baking, it should have a golden brown color on the exposed area.[5] The final volume will generally be two to three times larger than the batter volume.[6]
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Answer: Tom's

Question: Tom and Jacob are carrying Geiger counters through an old abandoned city near a nuclear plant. Tom walks into a hotel and looks around at all the paintings and old couches in the lobby. His Geiger counter remains silent, but as he walks up the stairs toward the second floor it starts to slowly but steadily make more sound. Jacob steps into a grocery store when his Geiger counter immediately starts making lots of noise, but his device starts to drop off in sound as he walks toward the freezer in the back of the store. Which person's Geiger counter currently has a weaker electric current? Hint: One reason radiation is dangerous is that it can't be detected with the senses. You normally can't see it, smell it, hear it, or feel it. Fortunately, there are devices such as Geiger counters that can detect radiation. A Geiger counter, like the one in Figure below , has a tube that contains atoms of a gas. If radiation enters the tube, it turns gas atoms to ions that carry electric current. The current causes the Geiger counter to click. The faster the clicks occur, the higher the level of radiation.
Answer:
Tom