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Wet the end of a microfiber cloth or towel and gently wipe it across your shoes. Get your shoes slightly damp but not soaking wet so the toothpaste can foam up. Try using toothpaste on fabric, mesh, or sneakers. Put the dab of toothpaste directly onto your shoes where there are heavy stains. Spread the toothpaste thin so it coats the entire area before working your toothbrush in small circular motions. Work the toothpaste into the shoes' fabric thoroughly before letting it set for 10 minutes. Make sure to use a non-gel toothpaste that's white. Other colors may leave stains on your shoes. You can use the same wet cloth as before to wipe the toothpaste off of your shoes. Make sure to get all of the toothpaste off your shoes so it doesn't leave any marks. Set your shoes in front of a fan or in a well-ventilated room. Leave the shoes to completely dry. Once they're dry, your shoes should look a few shades lighter. Leave your shoes outside in the sun to speed up the drying process.

Summary:
Wipe your shoes with a damp cloth to get them wet. Rub a pea-sized dab of toothpaste into the shoes with a toothbrush. Wipe the toothpaste and dirt away with a wet cloth. Let your shoes air dry completely for 2-3 hours.