Given the task definition and input, reply with output. Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Is pyridoxine effective to prevent hand-foot syndrome associated with capecitabine therapy : results of a randomized , double-blind , placebo-controlled study?
Answer: Pyridoxine is not effective in prevention of capecitabine-associated HFS.
no