Answer the following question given this paragraph: Tight junctions are composed of strands of transmembrane proteins embedded in the plasma membranes of two adjacent cells. The extracellular domains of these proteins directly join to one another. These joining proteins associate with peripheral membrane proteins located on the intracellular side of plasma membrane. These peripheral proteins anchor the strands to the actin component of the cytoskeleton, effectively forming a molecular complex that joins together the cytoskeletons of adjacent cells. The major types anchoring proteins of tight junctions are the claudins and the occludins. Q: What are the major types anchoring proteins? Choices: - semimetals and occludins - amino and fatty acids - claudins and semimetals - claudins and occludins A:
claudins and occludins