Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Does single copy of variant CYP2A6 alleles confer susceptibility to liver dysfunction in patients treated with coumarin?
Answer: No evidence was obtained that the studied polymorphism in CYP2A6 is a determinant of the coumarin-associated liver dysfunction.
[A]: no

[Q]: Question: Does restrictive left ventricular filling pattern result from increased left atrial pressure alone?
Answer: The restrictive filling pattern is distinguished from overfilling of a normal ventricle by a reduced and delayed E' and a shortened E deceleration time that reflect slow relaxation and increased LV stiffness.
[A]: no

[Q]: Question: Does delta opioid activation of the mitogen-activated protein kinase cascade require transphosphorylation of receptor tyrosine kinases?
Answer: Taken together, these data suggest that the transactivation of resident RTKs does not appear to be required for OR-mediated ERK phosphorylation and that the tyrosine-phosphorylated delta-OR, itself, is likely to act as its own signalling scaffold.
[A]:
no