Premise:
"were more successful with directive treatment interventions such as a 12-step approach or cognitive behavioral therapy."
Hypothesis: 12-step approaches and cognitive behavior therapy are generally not successful at all.

no

Premise:
"Yes, HOW! "
Hypothesis: The person didn't say anything at all.

no

Premise:
"All of this required muscle."
Hypothesis: The stronger guys did the bulk of it all.
it is not possible to tell