[Q]: I have a new situation: Tom and Brad were good friends but lived far away from each other. Tom lived in Hawaii so he visited all the islands and the volcanoes frequently. Brad lived on the East Coast, and he never visited The Hawaiian Islands. But I can use this background: The Hawaiian Islands ( Figure above ) are in the central Pacific Ocean. The islands are volcanoes that increase in age from southeast to northwest. The youngest island is the Big Island of Hawaii at the southeast end of the chain. The volcanoes get older through Maui, Kahoolawe, Lanai, Molokai, Oahu, Kauai, and Niihau Islands through the northwest. The Kilauea volcano on Hawaii has been erupting almost continuously since 1983. There are also eruptions at an underwater volcano called Loih What is an answer for this question: Which friend lived farther from Maui?
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[A]: Brad

[Q]: I have a new situation: Archaeologists studied data about human settlements. One was 100,000 years old called village R, and the other one was about 9,000 years old called village N. The older settlement was located in Africa, the other one wasn't. But I can use this background: The earliest members of the human species evolved around 200,000 years ago in Africa. Early humans lived in small populations of nomadic hunters and gatherers. Human beings remained in Africa until about 40,000 years ago. After that, they spread throughout Europe, Asia, and Australia. By 10,000 years ago, the first human beings colonized the Americas. During this long period of time, the total number of human beings increased very slowly. Birth rates were fairly high but so were death rates, producing low rates of population growth. What is an answer for this question: Which village had people that lived in smaller populations?
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[A]: village R

[Q]: I have a new situation: Two islands of identical size with similar ecosystems experienced different destinies. Caribu island, inhabited by more natives, hunted a few of the animal species there, contributing to the extinction of a few. People from Hiji island, were pescotarian, and hardly ever fished. But I can use this background: Biodiversity loss is the extinction of species (plant or animal) worldwide, and also the local reduction or loss of species in a certain habitat. The latter phenomenon can be temporary or permanent, depending on whether the environmental degradation that leads to the loss is reversible through ecological restoration / ecological resilience or effectively permanent (e.g. through land loss). Global extinction has so far been proven to be irreversible. Even though permanent global species loss is a more dramatic phenomenon than regional changes in species composition, even minor changes from a healthy stable state can have dramatic influence on the food web and the food chain insofar as reductions in only one species can adversely affect the entire chain (coextinction), leading to an overall reduction in biodiversity, possible alternative stable states of an ecosystem notwithstanding. Ecological effects of biodiversity are usually counteracted by its loss. Reduced biodiversity in particular leads to reduced ecosystem services and eventually poses an immediate danger for food security, also for humankind.[1] What is an answer for this question: Which island experienced less biodiversity loss?
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[A]: Hiji

[Q]: I have a new situation: Ben and Andy were two old friends. They both have high levels of cholesterol. Ben was prescribed cholesterol medication, while Andy didn't go to the doctor because he was careless. But I can use this background: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. What is an answer for this question: Which friend took a drug that changed the levels of HMG-CoA reductase?
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[A]:
Ben