Question:
that makes a difference

Does it follow that "Even so, that changes nothing."?
Answer:
no

Question:
His endurance is chalked up to his training as an architect and his embrace of bright colors.

Does it follow that "He went to school to be an architect."?
Answer:
yes

Question:
Over in the left transept, see Pietro Lorenzetti's noble Descent from the Crose

Does it follow that "Pietro Lorenzetti's work is in the left transept."?
Answer:
yes

Question:
They appreciated the town's loyalty to the crown, but the idea never occurred to anyone, let alone the two monarchs, that Madrid might one day become the capital.

Does it follow that "The town was disloyal to the crown."?
Answer:
no