Input: Article: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes by bacteria, hypothesized that an arsenic-containing dye with similar selective absorption properties could be used to treat bacterial infections. Arsphenamine was prepared as part of a campaign to synthesize a series of such compounds, and found to exhibit partially selective toxicity. Arsphenamine proved to be the first effective treatment for syphilis, a disease which prior to that time was incurable and led inexorably to severe skin ulceration, neurological damage, and death.[citation needed]

Now answer this question: What was the name of the first synthetic bacterial drug?

Output: arsphenamine

Input: Article: The meaning of federalism, as a political movement, and of what constitutes a 'federalist', varies with country and historical context.[citation needed] Movements associated with the establishment or development of federations can exhibit either centralising or decentralising trends.[citation needed] For example, at the time those nations were being established, factions known as "federalists" in the United States and Australia advocated the formation of strong central government. Similarly, in European Union politics, federalists mostly seek greater EU integration. In contrast, in Spain and in post-war Germany, federal movements have sought decentralisation: the transfer of power from central authorities to local units. In Canada, where Quebec separatism has been a political force for several decades, the "federalist" impulse aims to keep Quebec inside Canada.

Now answer this question: What countries advocate for a strong central government?

Output: United States and Australia

Input: Article: The history of biodiversity during the Phanerozoic (the last 540 million years), starts with rapid growth during the Cambrian explosiona period during which nearly every phylum of multicellular organisms first appeared. Over the next 400 million years or so, invertebrate diversity showed little overall trend, and vertebrate diversity shows an overall exponential trend. This dramatic rise in diversity was marked by periodic, massive losses of diversity classified as mass extinction events. A significant loss occurred when rainforests collapsed in the carboniferous. The worst was the Permian-Triassic extinction event, 251 million years ago. Vertebrates took 30 million years to recover from this event.

Now answer this question: In which era, did the first phylum of multicellular organisms appear?

Output:
the Cambrian explosion