Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: To study the mechanism of centrosome duplication in cycling cells, we established a novel system of multiple centrosome formation in two types of cells: CHO cells treated with RO3306, a Cyclin-dependent kinase 1 (Cdk1) inhibitor and DT40 cells, in which Cdks were knocked out by chemical genetics. Cdk1-inactivated cells initiated DNA replication and centrosome duplication at the onset of S phase. They became arrested at the end of G2, but the centrosome cycle continued to produce supernumerary centrioles/centrosomes without DNA endoreplication in those cells. Centrosomes were amplified in a highly synchronous and reproducible manner: all of them were located next to the nucleus and spread widely apart from each other with several m in distance. Double knockout of Cdk1 and Cdk2 caused cell cycle arrest at G1/S and centrosomes were no longer duplicated. However, cells continued to grow and increased their volume over 10-fold during 48 hr of culture. Centrosome components, including -tubulin and Cep135, were synthesized and accumulated during the arrest, allowing rapid centrosome multiplication upon recovery from the cell cycle arrest or expression of exogenous Plk4 in G1/S cells. Thus centrosome amplification results from the discoordination of the centrosome cycle from the progression of other cell cycle events, which is controlled by different levels of Cdk activities.
Example Output: Where in the cell do we find the protein Cep135?

Example Input: The following five destination shall never be missed *Blue Lagoon : Blue Lagoon geothermal spa is one of the most visited attractions in Iceland. The warm waters are rich in minerals and bathing in the Blue Lagoon is reputed to help some people suffering from skin diseases. The water temperature in the bathing and swimming area of the Lagoon averages 37degC - 39degC(99F -102F). The Blue Lagoon also operates a research and development facility to help find cures for skin diseases using the mineral-rich water. *Budapest: Budapest holds the title "City of Spas" since the year 1934, as it has more hot and medicinal water springs than any other capital city in the world. There are 118 springs in Budapest, providing over 70 million liters of hot water a day. The temperature of the waters is between 22degC and 40degC. *El Tatio: El Tatio is a geyser field located within the Andes Mountains of northern Chile at 4,320 meters above sea level. With over 80 active geysers, the site is the largest geyser field in the southern hemisphere and the third largest in the world. It is a major tourist attraction in Chile and is among the highest-elevation geyser fields in the world. The temperature of the waters goes between 70degC and 85degC. *Hokkaido: Visitors to the Japanese island of Hokkaido have plenty of options. These range from top resorts with thermal baths like the Spa Resort Hawaiians to small traditional inns that have their own small hot pools with water temperature comfortable to skin. Some bathing spots are outdoors and are not associated with any spa or inn. The classic forest and mountain landscapes of this nature-rich island make it a great choice for those seeking a science setting for their baths.
Example Output: Which site of the spring has the greatest gap of water temperature?

Example Input: Venomm is a fictional character in the Marvel Universe, distinct from the half-alien fictional character known as Venom.
Example Output:
With which fictional universe is the character Venomm associated?