In this task, you are given one French sentence. The major part of the sentences talk about health-related topics, but some of the them describe an organization and its activities. Your job is to translate the given sentences into English.

Les agents responsables de la vMCJ sont les prions, notamment la proteine prion de conformation anormale PrPSc, qui forment des agregats dans le tissu nerveux, conduisant progressivement a des lesions cerebrales et aux signes et symptomes caracteristiques de la maladie.
Causative agents of vCJD are prions, composed of misfolded prion proteins (PrPSc), which form aggregates in neurological tissue leading to progressive brain damage and characteristic signs and symptoms of the disease.