Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Does hypoxia interfere with connective tissue growth factor ( CTGF ) gene expression in human proximal tubular cell lines?
Answer: We provide evidence that hypoxia inhibits CTGF synthesis in human proximal tubular epithelial cells, involving HIF-1alpha. Under hypoxic conditions, induction of CTGF by TGF-beta was repressed. The reduced synthesis of the profibrotic factor CTGF may contribute to a potential protective effect of hypoxic preconditioning in acute renal injury.
[A]: yes

[Q]: Question: Does oxidative status in the macula densa modulate tubuloglomerular feedback responsiveness in angiotensin II-induced hypertension?
Answer: Under physiological conditions, TGF response is mainly controlled by the NO generated in the macula densa; in Ang II induced hypertension, the TGF response is mainly controlled by the O2- generated by the macula densa.
[A]: yes

[Q]: Question: Is the covariation between burnout and sick leave due to mental disorders explained by a shared genetic liability : a prospective swedish twin study with a five-year follow-up?
Answer: The association between burnout and sick leave due to stress-related and other mental disorders seems to be a reflection of a shared genetic liability.
[A]:
yes