Q: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Question: Does kRAS mutation predict the efficacy of neo-adjuvant chemoradiotherapy in rectal cancer : a systematic review and meta-analysis?
Answer: Based on these data, the presence of KRAS mutation does not affect tumor down-staging or cancer specific survival following neo-adjuvant CRT and surgery for rectal cancer.
A:
no