Given the task definition and input, reply with output. Generate a question which can yield the answer mentioned in the input. Generated question must be answered by the answer provided in input, without using any extra knowledge.

Context : On 17 December 1830, at the age of 47, Simon Bolivar died of tuberculosis in the Quinta de San Pedro Alejandrino in Santa Marta, Gran Colombia (now Colombia).
Answer : tuberculosis
What illness negatively impacted Simon Bolivar?