IN: Jewel was born May 23, 1974 in Payson, Utah, the second child of Attila Kuno "Atz" Kilcher and Lenedra Jewel Kilcher (nee Carroll). At the time of her birth, her parents had been living in Utah with her elder brother, Shane; her father was attending Brigham Young University. She is a first cousin once removed of actress Q'orianka Kilcher. Her father, originally from Alaska, was a Mormon, though the family stopped attending The Church of Jesus Christ of Latter-day Saints after her parents' divorce when she was eight years old.

In 2003 Jewel released the album 0304. Following the limited success of "Serve the Ego", Jewel moved to a more pop-oriented sound with the release of the single "Intuition". The song reached No. 5 on the Billboard Adult Pop Songs chart and No. 20 on the Billboard Hot 100. On May 2, 2006, Jewel released her sixth album Goodbye Alice in Wonderland. The album received mixed reviews, but still managed to debut at No. 8 on the Billboard Albums Chart and sold 82,000 copies in its first week. The lead single "Again and Again" had success on Adult Top 40 Radio, peaking at No. 16. The second single "Good Day" was released to radio in late June and peaked at No. 30 on the Adult Pop Songs charts. A video for "Stephenville, TX", her next single, was seen on Yahoo! Launch. After a photo shoot at her Texas ranch, Jewel spontaneously decided to have photographer Kurt Markus shoot the music video for the song "Goodbye Alice in Wonderland". According to an Atlantic Records press release, "The homegrown clip beautifully reflects both the song's organic, intimate sound and its powerfully autobiographical story." CMT music critic Timothy Duggan praised the album: "This album showcases Jewel's unique talent as a lyricist, alongside a definite growth in her musicianship. It is what Pieces of You might have been had Jewel had the musical knowledge then that she has now. A very satisfying work, all in all." Rolling Stone, however, called the album "overdone and undercooked" with a rating of 2 stars out of 5.

what happened in 2003?

OUT: In 2003 Jewel released the album 0304.

IN: Dave Holland (born 1 October 1946) is an English jazz double bassist, composer and bandleader who has been performing and recording for five decades. He has lived in the United States for over 40 years. His work ranges from pieces for solo performance to big band. Holland runs his own independent record label, Dare2, which he launched in 2005.

During the 1990s, Holland renewed an affiliation, begun in the 1970s, with Joe Henderson, joining the tenor saxophonist on So Near (So Far), a tribute to Miles Davis, and Porgy & Bess. Holland also reunited with vocalist Betty Carter, touring and recording the live album Feed the Fire (1993). Fellow Davis alumnus Herbie Hancock invited Holland to tour with him in 1992, subsequently recording The New Standard. Holland joined Hancock's band again in 1996. He was also part of the sessions for River: The Joni Letters, winner of the 2008 Grammy Award for Album of the Year. As a leader, Holland formed his third quartet and released Dream of the Elders (1995), which introduced the vibraphonist Steve Nelson to his ensembles. Holland formed a quintet that includes tenor saxophonist Chris Potter, trombonist Robin Eubanks and, a more recent addition, drummer Nate Smith. Their recordings include Points of View, Prime Directive, Not for Nothin, Extended Play: Live at Birdland and Critical Mass. In addition to releasing four quintet albums on ECM, Holland debuted his Big Band, which released What Goes Around in 2002. The album won Holland his first Grammy as a leader, in the Best Large Jazz Ensemble Album category. The second Big Band recording, Overtime (2005), again won the Grammy in the Best Large Jazz Ensemble Album category; it was released on Holland's Dare2 label, which he formed that year. In 2009, Holland was a co-founder of an all-star group called the Overtone Quartet. The group consisted of Holland on bass, Chris Potter on tenor saxophone, Jason Moran on piano, and Eric Harland on drums. The group toured extensively throughout the United States and Europe.

What did he lead at that time?

OUT: Holland debuted his Big Band,

IN: Henrietta Lacks (born Loretta Pleasant; August 1, 1920 - October 4, 1951) was an African-American woman whose cancer cells are the source of the HeLa cell line, the first immortalized cell line and one of the most important cell lines in medical research. An immortalized cell line will reproduce indefinitely under specific conditions, and the HeLa cell line continues to be a source of invaluable medical data to the present day. Lacks was the unwitting source of these cells from a tumor biopsied during treatment for cervical cancer at Johns Hopkins Hospital in Baltimore, Maryland, U.S., in 1951. These cells were then cultured by George Otto Gey who created the cell line known as HeLa, which is still used for medical research.

George Otto Gey, the first researcher to study Lacks's cancerous cells, observed that her cells were unique in that they reproduced at a very high rate and could be kept alive long enough to allow more in-depth examination. Until then, cells cultured for laboratory studies survived for only a few days at most, which wasn't long enough to perform a variety of different tests on the same sample. Lacks's cells were the first to be observed that could be divided multiple times without dying, which is why they became known as "immortal." After Lacks' death, Gey had Mary Kubicek, his lab assistant, took further HeLa samples while Henrietta's body was at Johns Hopkins' autopsy facility. The roller-tube technique was the method used to culture the cells obtained from the samples that Kubicek collected. Gey was able to start a cell line from Lacks's sample by isolating one specific cell and repeatedly dividing it, meaning that the same cell could then be used for conducting many experiments. They became known as HeLa cells, because Gey's standard method for labeling samples was to use the first two letters of the patient's first and last names. The ability to rapidly reproduce HeLa cells in a laboratory setting has led to many important breakthroughs in biomedical research. For example, by 1954, Jonas Salk was using HeLa cells in his research to develop the polio vaccine. To test his new vaccine, the cells were mass-produced in the first-ever cell production factory. Additionally, Chester M. Southam, a leading virologist, injected HeLa cells into cancer patients, prison inmates, and healthy individuals in order to observe whether cancer could be transmitted as well as to examine if one could become immune to cancer by developing an acquired immune response. HeLa cells were in high demand and put into mass production. They were mailed to scientists around the globe for "research into cancer, AIDS, the effects of radiation and toxic substances, gene mapping, and countless other scientific pursuits". HeLa cells were the first human cells successfully cloned in 1955, and have since been used to test human sensitivity to tape, glue, cosmetics, and many other products. Since the 1950s, scientists have grown 20 tons of her cells, and there are almost 11,000 patents involving HeLa cells. In the early 1970s, a large portion of other cell cultures became contaminated by HeLa cells. As a result, members of Henrietta Lacks's family received solicitations for blood samples from researchers hoping to learn about the family's genetics in order to differentiate between HeLa cells and other cell lines. Alarmed and confused, several family members began questioning why they were receiving so many telephone calls requesting blood samples. In 1975, the family also learned through a chance dinner-party conversation that material originating in Henrietta Lacks was continuing to be used for medical research. The family had never discussed Henrietta's illness and death among themselves in the intervening years but with the increased curiosity about their mother and her genetics, they now began to ask questions.

Is it still used?

OUT:
Since the 1950s, scientists have grown 20 tons of her cells, and there are almost 11,000 patents