Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Are immunologic marker paths for seroconversion : single determinations of immunoglobulin A and beta 2-microglobulin adequate to estimate time of HIV infection . Multicohort Analysis Project Workshop . Part II?
Answer: Further study of how serum IgA reflects HIV infection and careful clinical and statistical assessment of reduced beta 2M from 5 or 6 years after HIV infection are needed. The dependence of marker paths on mode of HIV transmission suggests that sexual transmission may have implications for HIV disease progression. The feasibility of using serum IgA and beta 2M, evaluable in single stored blood samples, to estimate time of HIV infection has been set back by our results.

A: no
****
Q: Question: Does the bradykinin B1 receptor antagonist BI113823 reverse inflammatory hyperalgesia by desensitization of peripheral and spinal neurons?
Answer: The selective bradykinin B1 receptor antagonist BI113823 reduces CFA-induced mechanical hyperalgesia which is mediated via antagonism of peripheral as well as spinal bradykinin B1 receptors. The selective modulation of CFA-sensitized spinal NS neurons by BI113823 could be a promising property for the treatment of inflammatory pain.

A: yes
****
Q: Question: Does polymerase I and transcript release factor act as an essential modulator of glioblastoma chemoresistance?
Answer: Our results indicate that PTRF acts as a modulator in GBM chemoresistance.

A:
yes
****