In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: Indinavir is a selective inhibitor of HIV protease because:
Options: <1> By hydrolysis, the active drug is generated. <2> Rents irreversibly the active center of the enzyme. <3> Its structure mimics the transition state of the reaction catalyzed by the enzyme. <4> It is a suicide inhibitor. <5> Its symmetric structure interacts effectively with the active center of the enzyme.
[EX A]: 3

[EX Q]: Question: The eudismic index is a parameter with pharmacological interest that expresses the relationship between:
Options: <1> Two diastereomer drugs. <2> Two bioisostero drugs. <3> Two enantiomers <4> A drug and a prodrug, structural analog. <5> Two structural modifications, one hydrophilic and one lipophilic, of a certain drug.
[EX A]: 3

[EX Q]: Question: In which part of the cell is ribosomal RNA synthesized ?:
Options: <1> Nucleolo. <2> Ribosomes <3> Vacuolas <4> Golgi apparatus. <5> Endoplasmic reticulum.
[EX A]:
1