Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Are synthetic antifibrinolytics associated with an increased incidence of baffle fenestration closure after the modified Fontan procedure?
Answer: Use of epsilon-aminocaproic acid and tranexamic acid is not associated with early baffle fenestration closure after the modified Fontan procedure. It is concluded that these agents can be used without increasing the risk of spontaneous baffle fenestration closure.

A: no
****
Q: Question: Does pI3K and Bcl-2 inhibition prime glioblastoma cells to apoptosis through downregulation of Mcl-1 and Phospho-BAD?
Answer: Combination therapy with ABT-263 and GDC-0941 has novel therapeutic potential by specifically targeting aberrantly active, deregulated pathways in GBM, overcoming endogenous resistance to apoptosis.

A: yes
****
Q: Question: Does rSPO3 expand intestinal stem cell and niche compartments and drives tumorigenesis?
Answer: We provide in vivo evidence that RSPO3 stimulates the crypt stem cell and niche compartments and drives rapid intestinal tumorigenesis. This establishes RSPO3 as a potent driver of intestinal cancer and proposes RSPO3 as a candidate target for therapy in patients with colorectal cancer harbouring RSPO3 fusions.

A:
yes
****