Given the task definition and input, reply with output. From the given sentence, extract the phrase (often noun or verb) that carries the given relationship. The generated phrase should be present in the sentence.

Given Relationship: 'be use with', Sentence: 'The Prescribing Information LEVAQUIN may not be effective if used with quinine to treat an array of bacterial infections among LEVAQUIN was approved recently by the FDA , levaquin and functionally would levaquin not be appropriate for use by children under 18 teardrop of age .'
with