Give some stream of consciousness and then the answer. The 2010 live-action film Alice in Wonderland, fashioned as a sequel to the novel, features Helena Bonham Carter as the Red Queen. Bonham Carter's head was digitally increased three times its original size on screen. Bonham Carter's character is a combination of the Red Queen, the Duchess and the Queen of Hearts. From the original Red Queen, this character gets only a relationship to the White Queen. Here the Red Queen is the older sister of the White Queen, and is jealous of her sister, whom her subjects genuinely love. From the original John Tenniel illustrations of the Duchess, she gets a massive head in proportion to her body and a retinue of frog footmen. The White Queen theorizes that the movie's Red Queen has a tumor pressing against her brain, explaining both her large head and her deranged behaviour. Most of her characteristics are taken from the Queen of Hearts, including:

Based on this passage, who played the red queen in alice in wonderland?
To answer this question, we should know that: The 2010 live-action film Alice in Wonderland, fashioned as a sequel to the novel, features Helena Bonham Carter as the Red Queen.
Therefore, the answer is Helena Bonham Carter.