Given the task definition and input, reply with output. Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does estradiol bound to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro?
Answer: Estradiol concentrations in hyperestrogenemic syndromes may interfere with INS binding to its receptor producing significant INS resistance.
yes