Q: Question: "How severe can shift work be when referring to its potential effect on humans?" Context: "Shift-work or chronic jet-lag have profound consequences on circadian and metabolic events in the body. Animals that are forced to eat during their resting period show increased body mass and altered expression of clock and metabolic genes.[medical citation needed] In humans, shift-work that favors irregular eating times is associated with altered insulin sensitivity and higher body mass. Shift-work also leads to increased metabolic risks for cardio-metabolic syndrome, hypertension, inflammation." Answer:
A: profound

Q: Question: "Cartridges stored the information for?" Context: "Nintendo was not as restrictive as Sega, which did not permit third-party publishing until Mediagenic in late summer 1988. Nintendo's intention, however, was to reserve a large part of NES game revenue for itself. Nintendo required that they be the sole manufacturer of all cartridges, and that the publisher had to pay in full before the cartridges for that game be produced. Cartridges could not be returned to Nintendo, so publishers assumed all the risk. As a result, some publishers lost more money due to distress sales of remaining inventory at the end of the NES era than they ever earned in profits from sales of the games. Because Nintendo controlled the production of all cartridges, it was able to enforce strict rules on its third-party developers, which were required to sign a contract by Nintendo that would obligate these parties to develop exclusively for the system, order at least 10,000 cartridges, and only make five games per year. A 1988 shortage of DRAM and ROM chips also reportedly caused Nintendo to only permit 25% of publishers' requests for cartridges. This was an average figure, with some publishers receiving much higher amounts and others almost none. GameSpy noted that Nintendo's "iron-clad terms" made the company many enemies during the 1980s. Some developers tried to circumvent the five game limit by creating additional company brands like Konami's Ultra Games label; others tried circumventing the 10NES chip." Answer:
A: games

Q: Question: "Who took charge of the landscape?" Context: "With the defeat of the Confederacy in 1865, the Reconstruction Era began. The United States abolished slavery without compensation to slaveholders or reparations to freedmen. A Republican Party coalition of black freedmen, northern carpetbaggers and local scalawags controlled state government for three years. The white conservative Democrats regained control of the state legislature in 1870, in part by Ku Klux Klan violence and terrorism at the polls, to suppress black voting. Republicans were elected to the governorship until 1876, when the Red Shirts, a paramilitary organization that arose in 1874 and was allied with the Democratic Party, helped suppress black voting. More than 150 black Americans were murdered in electoral violence in 1876." Answer:
A: Ku Klux Klan

Q: Question: "What did the Grand Tour influence?" Context: "By the mid 18th century, the movement broadened to incorporate a greater range of Classical influences, including those from Ancient Greece. The shift to neoclassical architecture is conventionally dated to the 1750s. It first gained influence in England and France; in England, Sir William Hamilton's excavations at Pompeii and other sites, the influence of the Grand Tour and the work of William Chambers and Robert Adam, was pivotal in this regard. In France, the movement was propelled by a generation of French art students trained in Rome, and was influenced by the writings of Johann Joachim Winckelmann. The style was also adopted by progressive circles in other countries such as Sweden and Russia." Answer:
A:
neoclassical architecture