Problem: The emergence of resistance of bacteria to antibiotics is a common phenomenon. Emergence of resistance often reflects evolutionary processes that take place during antibiotic therapy. The antibiotic treatment may select for bacterial strains with physiologically or genetically enhanced capacity to survive high doses of antibiotics. Under certain conditions, it may result in preferential growth of resistant bacteria, while growth of susceptible bacteria is inhibited by the drug. For example, antibacterial selection for strains having previously acquired antibacterial-resistance genes was demonstrated in 1943 by the LuriaDelbruck experiment. Antibiotics such as penicillin and erythromycin, which used to have a high efficacy against many bacterial species and strains, have become less effective, due to the increased resistance of many bacterial strains.
What is a modern occurrence with high doeses?
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Answer: unanswerable

Problem: All versions incorporate a top-loading slot for game cartridges, although the shape of the slot differs between regions to match the different shapes of the cartridges. The MULTI OUT connector (later used on the Nintendo 64 and GameCube) can output composite video, S-Video and RGB signals, as well as RF with an external RF modulator. Original versions additionally include a 28-pin expansion port under a small cover on the bottom of the unit and a standard RF output with channel selection switch on the back; the redesigned models output composite video only, requiring an external modulator for RF.
How many pins did the SNES expansion port have?
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Answer: 28

Problem: Following Die Another Day, Madonna collaborated with fashion photographer Steven Klein in 2003 for an exhibition installation named X-STaTIC Pro=CeSS. It included photography from a photo shoot in W magazine, and seven video segments. The installation ran from March to May in New York's Deitch Projects gallery. It traveled the world in an edited form. The same year, Madonna released her ninth studio album, American Life, which was based on her observations of American society; it received mixed reviews. She commented, "[American Life] was like a trip down memory lane, looking back at everything I've accomplished and all the things I once valued and all the things that were important to me." Larry Flick from The Advocate felt that "American Life is an album that is among her most adventurous and lyrically intelligent" while condemning it as "a lazy, half-arsed effort to sound and take her seriously." The title song peaked at number 37 on the Hot 100. Its original music video was canceled as Madonna thought that the video, featuring violence and war imagery, would be deemed unpatriotic since America was then at war with Iraq. With four million copies sold worldwide, American Life was the lowest-selling album of her career at that point.
What was Madonna's ninth album called?
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Answer:
American Life