Given an abstract of a paper, generate a title for this paper such that conveys the key focus of the paper.

Input: Consider Input: Abstract: A clinical trial was undertaken to assess the effects of oral H1 (diphenhydramine hydrochloride) and H2 (cimetidine) histamine blockade on nasal resistance induced by topical histamine. Ten adult volunteers were tested on two separate occasions. Their noses were pretreated by oral administration of either combined H1 and H2 histamine antagonists or H1 antagonist and placebo. The nasal airflow resistive response to topical histamine was then determined. Combined histamine antagonism was significantly more effective in reducing the nasal resistive response to topical histamine than H1 antagonist alone (p less than 0.0001). Furthermore, ingestion of the oral H1 histamine antagonist, diphenhydramine hydrochloride, alone led to an increase in resistance of the unprovoked nose, whereas combined H1 and H2 antagonism did not lead to a significant change.

Output: The effects of combined H1 and H2 histamine antagonists on alterations in nasal airflow resistance induced by topical histamine provocation.

Input: Consider Input: Abstract: The best treatment for diseases of the hip can begin if one diagnoses the disorder as soon as possible after onset. In many cases, successful management of the disease will prevent permanent damage to the hip joint. If injury occurs to the developing hip joint, major hip surgery may be necessary in adult life.

Output: Diseases of the developing hip joint.

Input: Consider Input: Abstract: Fifteen neutropenic febrile episodes occurred in 29 patients undergoing chemotherapy for malignant germ cell tumors of the ovary. Vincristine, actinomycin-D, and cyclophosphamide were used in 24 patients; cis-diamminedichloroplatinum, vinblastine, and bleomycin in three; and both regimens in two. All 15 patients were treated with antibiotic combinations (gentamicin and clindamycin in 12 cases), usually until neutropenia resolved. The mean nadir total granulocyte count was 123/mm3. There was no septicemia or drug-related deaths. With reduction in chemotherapy dosage, 87% of patients tolerated subsequent courses. The survival rates in this disease are excellent, although toxicity is substantial from both regimens. These neutropenic febrile episodes can be managed successfully without interrupting chemotherapy.
Output: Neutropenia and fever in patients undergoing combination chemotherapy for malignant germ cell tumors of the ovary.