Context and question: Pfizer, once the city's second largest employer, operated a large pharmaceutical research facility on the northeast side of Ann Arbor. On 22 January 2007, Pfizer announced it would close operations in Ann Arbor by the end of 2008. The facility was previously operated by Warner-Lambert and, before that, Parke-Davis. In December 2008, the University of Michigan Board of Regents approved the purchase of the facilities, and the university anticipates hiring 2,000 researchers and staff during the next 10 years. The city is the home of other research and engineering centers, including those of Lotus Engineering, General Dynamics and the National Oceanic and Atmospheric Administration (NOAA). Other research centers sited in the city are the United States Environmental Protection Agency's National Vehicle and Fuel Emissions Laboratory and the Toyota Technical Center. The city is also home to National Sanitation Foundation International (NSF International), the nonprofit non-governmental organization that develops generally accepted standards for a variety of public health related industries and subject areas.
What company announced it would close operations by the end of 2007?
Answer: unanswerable
Context and question: Chris Daughtry's performance of Fuel's "Hemorrhage (In My Hands)" on the show was widely praised and led to an invitation to join the band as Fuel's new lead singer, an invitation he declined. His performance of Live's version of "I Walk the Line" was well received by the judges but later criticized in some quarters for not crediting the arrangement to Live. He was eliminated at the top four in a shocking result.
Fuel asked Chris Daughtry to become what?
Answer: lead singer
Context and question: Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which hinders the entry of drugs and makes many antibiotics ineffective. The two antibiotics most commonly used are isoniazid and rifampicin, and treatments can be prolonged, taking several months. Latent TB treatment usually employs a single antibiotic, while active TB disease is best treated with combinations of several antibiotics to reduce the risk of the bacteria developing antibiotic resistance. People with latent infections are also treated to prevent them from progressing to active TB disease later in life. Directly observed therapy, i.e., having a health care provider watch the person take their medications, is recommended by the WHO in an effort to reduce the number of people not appropriately taking antibiotics. The evidence to support this practice over people simply taking their medications independently is poor. Methods to remind people of the importance of treatment do, however, appear effective.
What complication does the use of combinations of antibiotics for active TB prevent?
Answer:
antibiotic resistance