Given the task definition and input, reply with output. In this task, you are given two facts, and a multiple-choice question. Based on the given facts, answer the question with index of the correct option (e.g, "A").

Fact1: disease has a negative impact on an organism, Fact2: Organisms or living beings are literally things that are alive., Question: Disease has what kind of effect on a living being? (A) it has a negative effect (B) Abnormal cell growth (C) direct damage to the lungs (D) it helps living beings eat (E) it makes living beings faster (F) it is good for living beings (G) cause their death (H) Plant growth is reduced
A