Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Is cYP3A5 genotype associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients?
Answer: We conclude that patients expressing CYP3A5 need more tacrolimus to reach target concentrations and have a lower tacrolimus exposure shortly after transplantation. This delay in reaching target concentrations, however, did not result in an increased incidence of early BPAR and therefore, genotyping for CYP3A5 is unlikely to improve short-term transplantation outcome.
no

Question: Does glutamine supplementation prevent bacterial translocation after non-lethal haemorrhage in rats?
Answer: Glutamine supplementation before haemorrhage did not reduce bacterial translocation to mesenteric lymph nodes in this rat model.
no

Question: Does e2F3a gene expression have prognostic significance in childhood acute lymphoblastic leukemia?
Answer: Low expression of E2F3a was associated with inferior prognosis in childhood ALL. An algorithm composed of E2F3a expression and MRD could predict relapse or induction failure more precisely than that of the current risk stratification.
yes