This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Example Input: TB infection begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate within endosomes of alveolar macrophages. Macrophages identify the bacterium as foreign and attempt to eliminate it by phagocytosis. During this process, the bacterium is enveloped by the macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In the phagolysosome, the cell attempts to use reactive oxygen species and acid to kill the bacterium. However, M. tuberculosis has a thick, waxy mycolic acid capsule that protects it from these toxic substances. M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell.
Example Output: What specific part of the lungs marks the start of tuberculosis infection?

Example Input: A major problem in the managing of the Luftwaffe was Hermann Goring. Hitler believed the Luftwaffe was "the most effective strategic weapon", and in reply to repeated requests from the Kriegsmarine for control over aircraft insisted, "We should never have been able to hold our own in this war if we had not had an undivided Luftwaffe". Such principles made it much harder to integrate the air force into the overall strategy and produced in Goring a jealous and damaging defence of his "empire" while removing Hitler voluntarily from the systematic direction of the Luftwaffe at either the strategic or operational level. When Hitler tried to intervene more in the running of the air force later in the war, he was faced with a political conflict of his own making between himself and Goring, which was not fully resolved until the war was almost over. In 1940 and 1941, Goring's refusal to cooperate with the Kriegsmarine denied the entire Wehrmacht military forces of the Reich the chance to strangle British sea communications, which might have had strategic or decisive effect in the war against the British Empire.
Example Output: Who did Hitler have a conflict over running the air force?

Example Input: The most famous reformer of Estonian, Johannes Aavik (18801973), used creations ex nihilo (cf. 'free constructions', Tauli 1977), along with other sources of lexical enrichment such as derivations, compositions and loanwords (often from Finnish; cf. Saareste and Raun 1965: 76). In Aavik's dictionary (1921), which lists approximately 4000 words, there are many words which were (allegedly) created ex nihilo, many of which are in common use today. Examples are
Example Output:
Of all of Estonian's language reformers who is the most well known?