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How to repair holes in drywall with spackle
Assess the size of the hole.
Spackle repairs holes up to the size of a hand or so, but any hole larger than the size of a fist will require the use of a support of some kind, unless they happen to have support behind the wallboard already.
Choose the correct spackle.
One way to classify spackle is by weight: the smaller the hole, the lighter the spackle you will need. Cut any loose or hanging pieces from the hole with a utility knife, or any sharp tool.