Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).

Input: Consider Input: Abstract: It is clear that some synovial inflammation occurs in joints affected by osteoarthritis (OA) and it is well recognized that many patients with OA experience a decrease in pain and joint stiffness following administration of salicylates or other nonsteroidal antiinflammatory drugs (NSAIDs). However, neither the extent to which synovitis contributes to the cartilage breakdown in OA nor the effects of chronic administration of NSAIDs on the natural history of OA in humans is known. Recent studies indicate that several NSAIDs, including salicylates, suppress proteoglycan synthesis in articular cartilage in vitro. The effect on OA cartilage is more marked than that on normal cartilage. Other studies show that salicylate feeding may suppress proteoglycan metabolism in degenerating cartilage in vivo, aggravating the decrease in proteoglycan content caused by the disease itself. However, no effect of salicylates on normal articular cartilage has been observed in vivo. In damaged cartilage the magnitude of NSAID-induced suppression of proteoglycan metabolism appears to be related inversely to the proteoglycan content of the tissue. In addition, the NSAIDs used in treatment of arthritis today may differ with respect to their in vivo effects on articular cartilage metabolism due, in part, to differences between the molar concentrations of these drugs in synovial fluid.
Which is the apt title for the abstract? option1: Nonsteroidal antiinflammatory drugs in treatment of osteoarthritis. option2: Plasma 1,25(OH)2D3 response to parathyroid hormone, cyclic adenosine monophosphate, and phosphorus depletion in the spontaneously hypertensive rat.

Output: Nonsteroidal antiinflammatory drugs in treatment of osteoarthritis.

Input: Consider Input: Abstract: This paper reports the Authors' 8 year experience in the clinical use of charcoal hemoperfusion as a means to reduce the weekly time of treatment in chronic uremic patients. Two different programmes were applied. Programme A (34 patients) which involved substituting the 3 procedures per week of standard dialysis (4 hours duration each) by 2 procedures of combined hemodialysis and hemoperfusion, again of 4 hours duration each. Programme B (18 patients) which involved substituting the 3 procedures per week of 4 hours duration by 3 procedures of 3 hours each, 2 of combined hemodialysis and hemoperfusion, 1 of conventional dialysis. The net weekly reduction was 33% for Programme A and 25% for Programme B. The efficacy of the two Programmes was evaluated by clinical, hematochemical, nutritional and instrumental parameters.
Which is the apt title for the abstract? option1: Hemoperfusion in reduced-time programmes for chronic uremia. Long-term results. option2: Metabolic effects of dietary fructose and sucrose in types I and II diabetic subjects.

Output: Hemoperfusion in reduced-time programmes for chronic uremia. Long-term results.

Input: Consider Input: Abstract: Passive elastic stiffness of muscle acting at the elbow was assessed in 19 normal subjects by measuring displacements produced by a torque motor acting at the joint. Stiffness ranged from 0.40 to 1.8 Nm/radian and was strongly correlated (r = 0.85) with upper arm volume, allowing us to define a "normal" range for stiffness when corrected for arm volume. In addition, the angle of the elbow with the arm fully relaxed and no external torque applied ("neutral" angle) was found to be 107 degrees +/- 10 degrees. Thus, we have quantified resting stiffness or "tone" in the arm and provided normal data for comparison with patients with pathophysiological conditions such as rigidity or spasticity.
Which is the apt title for the abstract? option1: Elastic properties of muscles measured at the elbow in man: I. Normal controls. option2: Prostaglandin release in multiple sclerosis: correlation with disease activity.
Output: Elastic properties of muscles measured at the elbow in man: I. Normal controls.