Given the task definition and input, reply with output. In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Royal Decree 450/2005, of April 22, regulates:
Options: <1> The Plans of Studies of Diploma in Nursing. <2> Accreditation minimums for the transformation of ATS Schools into Nursing Diploma Schools. <3> The professional competences of the Diploma in Nursing. <4> The Own Titles of Advanced Nursing. <5> The Nursing Specialties.
5