Question: John's first wife, Isabel, Countess of Gloucester, was released from imprisonment in 1214; she remarried twice, and died in 1217. John's second wife, Isabella of Angouleme, left England for Angouleme soon after the king's death; she became a powerful regional leader, but largely abandoned the children she had had by John. John had five legitimate children, all by Isabella. His eldest son, Henry III, ruled as king for the majority of the 13th century. Richard became a noted European leader and ultimately the King of the Romans in the Holy Roman Empire. Joan married Alexander II of Scotland to become his queen consort. Isabella married the Holy Roman Emperor Frederick II. His youngest daughter, Eleanor, married William Marshal's son, also called William, and later the famous English rebel Simon de Montfort. John had a number of illegitimate children by various mistresses, including nine sons Richard, Oliver, John, Geoffrey, Henry, Osbert Gifford, Eudes, Bartholomew and probably Philip and three daughters Joan, Maud and probably Isabel. Of these, Joan became the most famous, marrying Prince Llywelyn the Great of Wales.
Is there an answer to this question: How many legitimate children did John have?

Answer: five

Question: On New Year's Day in 1930, von Neumann married Mariette Kovesi, who had studied economics at the Budapest University. Before his marriage he was baptized a Catholic. Max had died in 1929. None of the family had converted to Christianity while he was alive, but afterwards they all did. They had one child, a daughter, Marina, who is now a distinguished professor of business administration and public policy at the University of Michigan. The couple divorced in 1937. In October 1938, von Neumann married Klara Dan, whom he had met during his last trips back to Budapest prior to the outbreak of World War II.
Is there an answer to this question: What was Von Neumann's wife's name?

Answer: Mariette Kovesi

Question: Genetically modified (GM) cotton was developed to reduce the heavy reliance on pesticides. The bacterium Bacillus thuringiensis (Bt) naturally produces a chemical harmful only to a small fraction of insects, most notably the larvae of moths and butterflies, beetles, and flies, and harmless to other forms of life. The gene coding for Bt toxin has been inserted into cotton, causing cotton, called Bt cotton, to produce this natural insecticide in its tissues. In many regions, the main pests in commercial cotton are lepidopteran larvae, which are killed by the Bt protein in the transgenic cotton they eat. This eliminates the need to use large amounts of broad-spectrum insecticides to kill lepidopteran pests (some of which have developed pyrethroid resistance). This spares natural insect predators in the farm ecology and further contributes to noninsecticide pest management.
Is there an answer to this question: What farming pest management technique does the use of larvae grown plants promote?

Answer: unanswerable

Question: The avian circulatory system is driven by a four-chambered, myogenic heart contained in a fibrous pericardial sac. This pericardial sac is filled with a serous fluid for lubrication. The heart itself is divided into a right and left half, each with an atrium and ventricle. The atrium and ventricles of each side are separated by atrioventricular valves which prevent back flow from one chamber to the next during contraction. Being myogenic, the heart's pace is maintained by pacemaker cells found in the sinoatrial node, located on the right atrium. The sinoatrial node uses calcium to cause a depolarizing signal transduction pathway from the atrium through right and left atrioventricular bundle which communicates contraction to the ventricles. The avian heart also consists of muscular arches that are made up of thick bundles of muscular layers. Much like a mammalian heart, the avian heart is composed of endocardial, myocardial and epicardial layers. The atrium walls tend to be thinner than the ventricle walls, due to the intense ventricular contraction used to pump oxygenated blood throughout the body. Avian hearts are generally larger than mammalian hearts when compared to body mass. This adaptation allows more blood to be pumped to meet the high metabolic need associated with flight.
Is there an answer to this question: Where is the heart contained in the avian circulatory system?

Answer:
fibrous pericardial sac