TASK DEFINITION: Given an abstract of a paper, generate a title for this paper such that conveys the key focus of the paper.
PROBLEM: Abstract: In a series of 715 patients operated on by microsurgical techniques for intracranial saccular aneurysms between 1970 and 1980, part of the aneurysmal sac was not obliterated in 28 aneurysms in 27 patients (3.8% of 715 cases). Clinical follow-up evaluation for 8 years (range 4 to 13 years) and angiographic follow-up studies for 6 years (range 2 to 10 years) in these 27 cases revealed that one aneurysm rest increased in size and bled twice, five were spontaneously obliterated, two decreased in size, 13 remained unchanged, and in seven cases no late follow-up angiography was performed. The incidence of rebleeding from an aneurysm rest was 3.7% of the 27 in whom the sac was not obliterated and 0.14% of all 715 patients who were operated on.

SOLUTION: Natural history of postoperative aneurysm rests.

PROBLEM: Abstract: Optical imaging of cortical activity offers several advantages over conventional electrophysiological and anatomical techniques. One can map a relatively large region, obtain successive maps to different stimuli in the same cortical area and follow variations in response over time. In the intact mammalian brain this imaging has been accomplished with the aid of voltage sensitive dyes. However, it has been known for many years that some intrinsic changes in the optical properties of the tissue are dependent on electrical or metabolic activity. Here we show that these changes can be used to study the functional architecture of cortex. Optical maps of whisker barrels in the rat and the orientation columns in the cat visual cortex, obtained by reflection measurements of the intrinsic signal, were confirmed with voltage sensitive dyes or by electrophysiological recordings. In addition, we describe an intrinsic signal originating from small arteries which can be used to investigate the communication between local neuronal activity and the microvasculature. One advantage of the method is that it is non-invasive and does not require dyes, a clear benefit for clinical applications.

SOLUTION: Functional architecture of cortex revealed by optical imaging of intrinsic signals.

PROBLEM: Abstract: A thyroid nodule comprised numerous polyclonal plasma cells inside cellular fibroblastic stroma, with residual thyroid tissue in the centre of the nodule. There was no associated paraproteinaemia. The residual thyroid tissue suggests that the exuberant granulation tissue in this case represents an unusual reaction to a colloid nodule. As far as we know, this is the first adequately documented case of the so called plasma cell granuloma of the thyroid.

SOLUTION:
Plasma cell granuloma of the thyroid.