Technologies based upon the polymerase chain reaction (PCR) method will become nearly ubiquitous gold standards of diagnostics of the near future, for several reasons. First, the catalog of infectious agents has grown to the point that virtually all of the significant infectious agents of the human population have been identified. Second, an infectious agent must grow within the human body to cause disease; essentially it must amplify its own nucleic acids in order to cause a disease. This amplification of nucleic acid in infected tissue offers an opportunity to detect the infectious agent by using PCR. Third, the essential tools for directing PCR, primers, are derived from the genomes of infectious agents, and with time those genomes will be known, if they are not already.
What must an infectious agent do to cause disease?
grow within the human body

In Rome, state cult to a living emperor acknowledged his rule as divinely approved and constitutional. As princeps (first citizen) he must respect traditional Republican mores; given virtually monarchic powers, he must restrain them. He was not a living divus but father of his country (pater patriae), its pontifex maximus (greatest priest) and at least notionally, its leading Republican. When he died, his ascent to heaven, or his descent to join the dii manes was decided by a vote in the Senate. As a divus, he could receive much the same honours as any other state deity libations of wine, garlands, incense, hymns and sacrificial oxen at games and festivals. What he did in return for these favours is unknown, but literary hints and the later adoption of divus as a title for Christian Saints suggest him as a heavenly intercessor. In Rome, official cult to a living emperor was directed to his genius; a small number refused this honour and there is no evidence of any emperor receiving more than that. In the crises leading up to the Dominate, Imperial titles and honours multiplied, reaching a peak under Diocletian. Emperors before him had attempted to guarantee traditional cults as the core of Roman identity and well-being; refusal of cult undermined the state and was treasonous.
As first citizen, what must the emperor's mores represent?
traditional

North Carolina's party loyalties have undergone a series of important shifts in the last few years: While the 2010 midterms saw Tar Heel voters elect a bicameral Republican majority legislature for the first time in over a century, North Carolina has also become a Southern swing state in presidential races. Since Southern Democrat Jimmy Carter's comfortable victory in the state in 1976, the state had consistently leaned Republican in presidential elections until Democrat Barack Obama narrowly won the state in 2008. In the 1990s, Democrat Bill Clinton came within a point of winning the state in 1992 and also only narrowly lost the state in 1996. In the early 2000s, Republican George W. Bush easily won the state by over 12 points, but by 2008, demographic shifts, population growth, and increased liberalization in heavily populated areas such as the Research Triangle, Charlotte, Greensboro, Winston-Salem, Fayetteville, and Asheville, propelled Barack Obama to victory in North Carolina, the first Democrat to win the state since 1976. In 2012, North Carolina was again considered a competitive swing state, with the Democrats even holding their 2012 Democratic National Convention in Charlotte. However, Republican Mitt Romney ultimately eked out a 2-point win in North Carolina, the only 2012 swing state that Obama lost, and one of only two states (along with Indiana) to flip from Obama in 2008 to the GOP in 2012.
North carolina voters have leaned republican since what year?
1976