You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a scientific passage and an answer, generate a question for the given answer.

Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Why? The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

New input: Passage: The biosphere includes all living things within all of their environments. It includes every part of the environment where life exists, from the upper reaches of the atmosphere to the top few meters of soil, to the bottoms of the oceans. An ecosystem is made up of the relationships among smaller groups of organisms with each other, and with their environment. Scientists often speak of the interrelatedness of living things, because, according to evolutionary theory, organisms adapt to their environment, and they must also adapt to other organisms in that environment. Answer: biosphere
Solution:
What includes all living things within all their environments, including everywhere life exists, from the upper atmosphere, to the top of the soil, to ocean bottoms?