Given a passage with a context and an answer, construct a question on the basis of the information present in the passage. Construct the question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) it answer uses text phrases from the passage. Avoid creating questions that (i) can't be answered correctly without actually understanding the passage and (ii) uses the same words or phrases given in the passage.

Ex Input:
Context: Some living kidney donors report lost income during recovery from surgery. Little is known about whether concern for living donor's lost income affects the decision to undergo donation evaluation and the willingness of transplant candidates to discuss living kidney donation (LKD) with others.", 'To examine whether transplant patients were told by potential donors about lost income concerns and whether patients chose not to discuss LKD with others due to lost income concerns.', "Kidney transplant patients (185 wait-listed candidates, 171 deceased donor recipients, and 100 live donor recipients) at 2 centers completed a questionnaire to assess whether concern about donor's lost income was a consideration in discussion about LKD with others.", 'One-third (32%) were told by a family member/friend that they were willing to donate but were concerned about potential lost income. The majority of those who expressed financial concern (64%) did not initiate donation evaluation. Many patients (42%) chose not to discuss living donation with a family member/friend due to concern about the impact of lost income on the donor. In the multivariable model, lower annual household income was the only statistically significant predictor of both having a potential donor expressing lost income concern and choosing not to talk to someone because of lost income concern.
Answer: Findings from the current study underscore how concern about income loss for living donors may affect decision-making by both transplant candidates and potential donors.

Ex Output:
Does concern for Lost Income Following Donation deter Some Patients From Talking to Potential Living Donors?

Ex Input:
Context: Postictal inhibition (PI) is a decrease in excitability that follows an epileptic seizure and decreases probability of new seizure occurrence. PI may involve both increased inhibition and persisting elevated excitation. Our experiments tested whether shorter trains of weak stimuli are able to unmask this residual increase of excitability during the PI.', 'Four epileptic afterdischarges (ADs) were evoked by intense electrical stimulation (20 s, 8 Hz, current intensity at 5x threshold) of the neocortex in two groups (A, B) of Wistar rats. Before the first AD and during the 10-min interictal period, 8-Hz trains of four weak pulses (half of the intensity used for the AD triggering; 4P) were applied every 20 s in group B and a single pulse with similar parameters in group A.', 'The number of interictal epileptiform events evoked by 4P in the group B was significantly higher than that in the group A (evoked by single pulses) except after the second AD. Epileptic events were triggered by 4P also immediately after the AD termination.
Answer: It is apparent that weak stimulation can trigger epileptic phenomena during PI. Our results indicate that it is no longer possible to perceive PI only as persisting extreme and active inhibition. An appropriate stimulation can reveal more subtle (but important) excitatory events contributing to the functional status during the postictal period.

Ex Output:
Do short bursts of weak pulses break postictal inhibition in the neocortex of Wistar rats?

Ex Input:
Context: Serum -hydroxybutyrate (-HB) is elevated in insulin resistance and diabetes. We tested the hypothesis that the -HB level predicts abnormal 1h glucose levels and -cell dysfunction inferred from plasma insulin kinetics during a 75g oral glucose tolerance test (OGTT).', 'This cross-sectional study included 217 patients at increased risk for diabetes. 75g OGTTs were performed with multiple postload glucose and insulin measurements over a 30-120min period. OGTT responses were analyzed by repeated measures analysis of variance (ANOVA). Multivariable logistic regression was used to predict 1h glucose 155mg/dL with -HB added to traditional risk factors.', 'MeanSD age was 5115years (44% male, 25% with impaired glucose tolerance). Fasting glucose and insulin levels, but not age or body mass index (BMI), were significantly higher in the second/third -HB tertiles (>3.9g/mL) than in the first tertile. Patients in the second/third -HB tertiles exhibited a higher glucose area under the receiver operating characteristics curve (AUC) and reduced initial slope of insulin response during OGTT. The AUC for predicting 1h glucose 155mg/dL was 0.82 for a base model that included age, gender, BMI, fasting glucose, glycated hemoglobin (HbA1c), and insulin, and increased to 0.86 with -HB added (p=0.015), with a net reclassification index of 52% (p<0.0001).
Answer: Fasting serum -HB levels predicted elevated 1h glucose during OGTT, potentially due to impaired insulin secretion kinetics. This association persisted even in patients with an otherwise normal insulin-glucose homeostasis. Measuring serum -HB could thus provide a rapid, inexpensive screening tool for detecting early subclinical hyperglycemia, -cell dysfunction, and increased risk for diabetes.

Ex Output:
Does serum -hydroxybutyrate ( -HB ) predict elevated 1 h glucose levels and early-phase -cell dysfunction during OGTT?