In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

[EX Q]: CRKL , an SH2 - SH3 - SH3 adapter protein , is one of the major tyrosine phosphoproteins detected in primary leukemic neutrophils from patients with CML .
[EX A]: tyrosine phosphoproteins

[EX Q]: Although polyubiquitin chains linked through Lys ( 29 ) of ubiquitin have been implicated in the targeting of certain substrates to proteasomes , the signaling properties of these chains are poorly understood .
[EX A]: polyubiquitin chains

[EX Q]: These data show that tyrosine phosphorylation by FES affects the interaction of BCR with multiple signaling partners and suggest a general role for BCR in non - receptor protein - tyrosine kinase regulation and signal transduction .
[EX A]:
tyrosine kinase