Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: "It's time to go back on offense," Lechleiter said in a recent interview. New treatments for diabetes and cancer now awaiting approval and increased sales of animal-health products and drugs in China and Japan are some of the aggressive moves he has in mind. He is also counting on a robust success rate among three dozen other experimental drugs now in mid- and late-stage trials, including a cancer drug called ramucirumab. "We're on the cusp of launching products in cancer and diabetes, two therapeutic areas where we're well established and where we have built out the infrastructure we need," Lechleiter said. "And we believe that's going to be the beginning of our return to growth." Skeptical investors only now appear to be catching on to Lilly's potential upside. After rising only 3 percent in 2013, badly underperforming a 27 percent average advance for other large drugmakers, the stock is up 6 percent this month. "Instead of having to play defense and manage through this difficult patent cliff, the company will be able to use additional cash flow to invest in its pipeline, to partner with others or make bolt-on acquisitions," said Atlantic Equities analyst Richard Purkiss. "The outlook is much brighter, and they'll try to get that message across in coming months." Lilly, which reports quarterly and 2013 results on Thursday, has forecast earnings of $2.77 to $2.85 per share this year, the final and worst year of its patent cliff. That's 41 percent less than 2010. Lilly last year sought U.S. approvals for four drugs, three of which Lechleiter said could be approved in 2014: ramucirumab for stomach cancer, and dulaglutide and empagliflozin for type 2 diabetes - the most common form of diabetes, which is closely linked to obesity. Analysts have forecast annual sales of more than $650 million for ramucirumab, saying sales could be far higher if the drug also wins approval for cancers of the colon, lung or liver. But they caution that the diabetes drugs may have a hard time competing against existing options. Lechleiter said Lilly plans to seek approval of necitumumab for squamous-cell lung cancer this year. The medicine, like ramucirumab, was acquired by Lilly through its $6.5 billion purchase of ImClone Systems in 2008. If approved, necitumumab could capture eventual annual sales of more than $1 billion, analysts say. Such sales could make a big difference for Lilly, whose annual revenue of $20 billion is far lower than Big Pharma rivals like Pfizer Inc and Merck & Co. In the meantime, Lilly is testing nearly 40 medicines in mid- and late stage studies, compared with only 7 in those stages of development a decade ago. They include new treatments for cholesterol, psoriasis, lupus, rheumatoid arthritis and Alzheimer's disease. Animal health unit Elanco, with annual sales of about $2 billion, is thriving as Lilly introduces new products and has expanded the business in China and other fast-growing markets. Many analysts are wary, however, of the company's ability to win approvals of prescription drugs because it has not launched any major products in recent years and has suffered setbacks in clinical trials, including ramucirumab's failure to delay progression of breast cancer. Of 20 analysts tracked by Thomson Reuters, 12 have hold or sell ratings on Lilly, versus 8 with buy ratings. Lilly shares trade at 19 times expected 2014 per-share earnings, compared to a price-to-earnings ratio of 14.6 for other large drugmakers. That could be more a reflection of the company's poor earnings this year than excitement about the stock. "We believe that overall the pipeline will disappoint investors," said Alex Arfaei of BMO Capital Markets in a research note, citing low sales expectations for ramucirumab and the new diabetes drugs. When Lilly's Zyprexa was confronted with cheaper generic treatments for schizophrenia in October 2011, it faced one of the industry's steepest patent cliffs ever, quickly losing 80 percent of its onetime $5 billion in annual sales. Similarly precipitous declines are expected for Cymbalta, Lilly's $5 billion-a-year antidepressant, which lost U.S. patent protection last month, and for blockbuster osteoporosis treatment Evista, which goes generic in March. Many other large drugmakers, when faced with patent expirations and earnings declines of lesser scope, have resorted to megamergers to cushion the blow from generics and prop up earnings with cost savings. Huge layoffs, sapped morale and poor track records in introducing new drugs are more common results. Pfizer Inc stands out, having snapped up U.S. rivals Warner-Lambert, Pharmacia and Wyeth since 2000. Lechleiter, who began his career at Lilly in 1979 as a senior organic chemist, has steadfastly spurned any suggestion of a big merger: "It's never entered our minds, and we remain adamantly opposed." John Boris, an analyst for Suntrust Robinson Humphrey, said he expects Lilly earnings to grow an average of 10 percent a year between 2015 and 2020, which would make it second to Bristol-Myers Squibb Co in profit growth over that period. Atlantic Equities' Purkiss said he anticipates Lilly will deliver industry-topping earnings growth in the "mid-teens" percentage range in 2015, 2016 and 2017. "The sentiment has been very negative on Lilly, but it looks like it will go from one of the most growth-starved to the fastest growing of the major U.S. drugmakers and the European players," Purkiss said. By avoiding a disruptive megamerger, Lilly has allowed itself to press ahead with ambitious research, said Barclays analyst Tony Butler. He said to date the company has met long-term sales and earnings forecasts it provided in 2009 - before patents went over the cliff - while maintaining its generous dividend, with a current yield of 3.6 percent. "At the time, the market was incredibly skeptical about Lilly's ability to fund its dividend and to have enough remaining cash flow to fund its business," said Butler. "Lilly proved everybody wrong." (This story has been refiled to change second subhead) Claim: Lilly CEO: 'It's time to go back on offense'.
[A]: After three years of seeing major drugs like Zyprexa for schizophrenia lose patent protection and wipe away billions of dollars in revenue, Eli Lilly and Co Chief Executive Officer John Lechleiter wants to change the game plan.

[Q]: Paragraph: Once an illness is added to the list of approved conditions, the board cannot remove it because state law does not give the board authority to do so, according to board spokeswoman Tessie Pollock. Petitions will be reviewed early next year. AIDS, Alzheimer's disease, and Amyotrophic lateral sclerosis, or ALS, are among the 21 current approved illnesses, along with cancer, epilepsy, glaucoma and Parkinson's disease. Earlier this year the board rejected petitions seeking to add anxiety and autism spectrum disorders as qualifying conditions. The board will for the first time open up a public comment period, beginning after its Jan. 8 meeting, said executive director Stephanie Louka. Final decisions on new accepting conditions would come after several months. ___ This story was first published on Dec. 25, 2019. It was updated on Dec. 27, 2019, to correct the name of the State Medical Board of Ohio spokeswoman. She is Tessie Pollock, not Tessa Pollock. It was also updated to clarify that the board says state law does not give it the authority to remove conditions from the list of approved conditions for which doctors can recommend medical marijuana to patients. Claim: Board to consider new conditions for medical marijuana use.
[A]: The state Medical Board is accepting new petitions through the end of the year from those seeking to add illnesses as qualifying conditions for physicians to recommend medical marijuana to Ohio patients, cleveland.com reported.

[Q]: Paragraph: Vasiliki Kostoula, a Greek breast cancer patient, is framed through a breast x-ray after a radiological medical examination in an Athens hospital October 29, 2008. REUTERS/Yannis Behrakis The study shows the benefits of genetic tests that give women with a family history of cancer the chance to take steps to increase their chances of survival, they said. "This is the first study to prove women survive longer with these preventive surgeries and shows the importance of genetic testing when there is a family history of early breast or ovarian cancer," Dr. Virginia Kaklamani of Northwestern University in Chicago wrote in a commentary about the study published in the Journal of the American Medical Association. Women with mutations in the BRCA1 or BRCA2 genes have a 56 to 84 percent higher risk of developing breast cancer during their lifetimes. Those with the BRCA1 mutation also have a 36 to 63 percent higher risk of ovarian cancer and those with the BRCA2 mutation have a 10 to 27 percent higher risk of ovarian cancer. Because of this, many women make the difficult choice to have their breasts or ovaries and fallopian tubes surgically removed to reduce their risk. Dr. Susan M. Domchek of the University of Pennsylvania School of Medicine in Philadelphia and colleagues studied the effectiveness of these procedures in 2,482 women with BRCA mutations, including 247 women who had risk-reducing surgery to remove their breasts and 993 who had risk-reducing surgery to remove their ovaries. No woman who had a mastectomy developed breast cancer during the three years of follow-up testing. Seven percent of women who decided against a mastectomy were diagnosed with breast cancer in the same period. "Our results confirm that risk-reducing mastectomy is associated with a significant reduction in breast cancer risk," Domchek and colleagues wrote. Women with BRCA1 and BRCA2 mutations who had their ovaries and fallopian tubes removed had similar results. About 10 to 20 percent of breast and ovarian cancers are due to BRCA1 or BRCA2 genes. "Most of these women will die of ovarian cancer, so you can save 20 percent of them with the prophylactic surgery," Kaklamani said. "And you can save the majority of women who would have died of their breast cancer," she added. She said primary care physicians, gynecologists and women "need to be more aware that these tests exist." Dr. Sandhya Pruthi, a breast cancer expert at the Mayo Clinic in Rochester, Minnesota, who counsels women with BRCA mutations, said the study adds more evidence that the surgery can help save lives, but the choice is never easy. "It's not cookie-cutter medicine," Pruthi, who was not involved in the study, said in a telephone interview. She said women need to come to terms with the psychological issues involved in having their breasts removed, and younger women who have their ovaries removed must contend with early menopause symptoms. "It's not a decision made on a single visit," she said. According to the American Cancer Society and the International Agency for Research on Cancer, 1.3 million new breast cancer cases are diagnosed around the world every year and it kills 465,000 women annually, making it the leading global cancer killer of women. Claim: Surgery prevents breast cancers in high-risk women.
[A]:
Women with mutations in the well-known BRCA1 or BRCA2 genes who have their breasts and ovaries removed are much more likely to survive than women who do not get preventive surgery, U.S. researchers said on Tuesday.