Q: Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
Abstract: Five insulin dependent diabetic patients are reported on who had a few small retinal cotton-wool spots or 'soft exudates' either totally isolated or associated with fewer than 10 microaneurysms. These observations suggest that cotton-wool spots may be an early finding in diabetic retinopathy. Significant biological abnormalities in these patients were high levels of glycosylated haemoglobin and mild increases in thrombin generation, indicating slight activation of the coagulation system. The possible significance of these clinical and biological findings is discussed.
Which is the apt title for the abstract? option1: Retinal cotton-wool spots: an early finding in diabetic retinopathy? option2: Quantitative evaluation of aortic insufficiency by continuous wave Doppler echocardiography.
A:
Retinal cotton-wool spots: an early finding in diabetic retinopathy?