Write a question about the following article.

The Tramadol has no effect . Pain is getting worse , but I can still tell hot from cold , though I do n't do so good at the vibration tests . I use a lot of post - it notes and such to help me remember things and my wife helps as well . I have slowed my work load down some and this helps with the dystonia .

Question:
What may happen if the Tramadol has no effect ?
Select from: 1. I may have to make my new medicine from scratch . 2. None of the above choices . 3. I may have to go to the doctor and ask for more . 4. I may have to go to the hospital and get new medicine .