TASK DEFINITION: Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
PROBLEM: Abstract: The extended deep inferior epigastric flap, described by Taylor et al. in 1983, consists of the lower portion of the rectus abdominis muscle and a superolateral fasciocutaneous extension based on the periumbilical perforators. We have used this flap four times to close large defects of the abdomen, groin, and thigh and twice as a free flap to close wounds of the head and leg. There were no ischemic complications, and there was uncomplicated wound healing in the recipient and in the donor wounds. We recommend this highly versatile and reliable flap as one to be considered early in planning the closure of large wounds.
Which is the apt title for the abstract? option1: Clinical applications of the extended deep inferior epigastric flap. option2: Ocular toxicity from ethambutol [editorial]

SOLUTION: Clinical applications of the extended deep inferior epigastric flap.

PROBLEM: Abstract: This study has shown that a multidisciplinary group approach to counselling parents of burned children will decrease parental anxiety, and that medical, psychological and social problems will feature primarily in group discussions.
Which is the apt title for the abstract? option1: A multidisciplinary group approach to counselling the parents of burned children. option2: Proceedings of First International Symposium on Prevention of Allergic Diseases. June 24-27, 1984, Florence, Italy.

SOLUTION: A multidisciplinary group approach to counselling the parents of burned children.

PROBLEM: Abstract: The pressor response to exogenously infused angiotensin II is decreased in normal human and ovine pregnancy when compared to the nonpregnant state. This study was designed to determine the mechanism for decrease in target organ sensitivity by examining pregnancy-induced changes in the affinity and number of angiotensin II receptors in myometrium from pregnant and nonpregnant sheep. Tissues were obtained from four ovariectomized sheep given 50 micrograms estradiol-17 beta on days 3 and 5 postsurgery and from four pregnant sheep (mean gestational age 136 days). Binding of 125I-angiotensin II was determined in particulate fractions of myometrium prepared by differential centrifugation. The 125I-angiotensin II binding to myometrial preparations was specific, saturable, and linear with protein concentration. In the nonpregnant group, binding capacity for angiotensin II in myometrium was 502 +/- 76 fmol/mg protein, whereas in the pregnant group it was 184 +/- 65 fmol/mg protein (P less than .01). Receptor affinity also was less (Kd 1.72 +/- 0.39 nM) during pregnancy compared with the nonpregnant sheep uterus (3.9 +/- 0.80 nM; P less than .01). These data support the hypothesis that the decrease in target organ sensitivity to exogenously administered angiotensin II during pregnancy in human and ovine species may be secondary to a decrease in the total number and affinity of specific angiotensin II receptors.
Which is the apt title for the abstract? option1: Pregnancy causes a decrease in the number and affinity of myometrial angiotensin II receptors. option2: Roentgenographic findings of the cervical spine in asymptomatic people.

SOLUTION:
Pregnancy causes a decrease in the number and affinity of myometrial angiotensin II receptors.