Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Q: Multiple genes mutations is usually necessary to develop cancer.

A: What is usually necessary to develop cancer?
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Q: Spring tides are created when the sun and moon's tides match.

A: Which type of tides are created when the sun and moon's tides match?
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Q: Young roots and leaves are the major sites of gibberellin production.

A:
What are the major sites of gibberellin production?
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