Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

[Q]: Context: We review the current evidence for medical and surgical treatments of spontaneous intracerebral hemorrhage (ICH). Therapy with hemostatic agents (e.g. factor VIIa and tranexamic acid) if started early after bleeding onset may reduce hematoma expansion, but their clinical effectiveness has not been shown. Rapid anticoagulation reversal with prothrombin concentrates (PCC) plus vitamin K is the first choice in vitamin K antagonist-related ICH. In ICH related to dabigatran, anticoagulation can be rapidly reversed with idarucizumab. PCC are recommended for ICH related to FXa inhibitors, whereas specific reversal agents are not yet approved. While awaiting ongoing trials studying minimally invasive approaches or hemicraniectomy, the role of surgery in ICH remains to be defined. Therapies targeting downstream molecular cascades in order to prevent secondary neuronal damage are promising, but the complexity and multi-phased nature of ICH pathophysiology is challenging. Finally, in addition to blood pressure control, antithrombotic prevention after ICH has to consider the risk of recurrent bleeding as well as the risk of ischemic events. Treatment of acute ICH remains challenging, and many promising interventions for acute ICH await further evidence from trials.
Question: Which drug can be reversed with idarucizumab?
[A]: dabigatran

[Q]: Context: Transcription-coupled repair (TCR) is a subpathway of nucleotide excision repair (NER) that acts specifically on lesions in the transcribed strand of expressed genes. First reported in mammalian cells, TCR was then documented in Escherichia coli. In this organism, an RNA polymerase arrested at a lesion is displaced by the transcription repair coupling factor, Mfd. This protein recruits the NER lesion-recognition factor UvrA, and then dissociates from the DNA. UvrA binds UvrB, and the assembled UvrAB* complex initiates repair. In mutants lacking active Mfd, TCR is absent. A gene transcribed by the bacteriophage T7 RNA polymerase in E. coli also requires Mfd for TCR. The CSB protein (missing or defective in cells of patients with Cockayne syndrome, complementation group B) is essential for TCR in humans. CSB and its homologs in higher eukaryotes are likely functional equivalents of Mfd.
Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
[A]: the transcribed strand

[Q]: Context: In an endothermic reaction, it takes more energy to break bonds in the reactants than is released when new bonds form in the products. The word "endothermic" literally means "taking in heat." A constant input of energy, often in the form of heat, is needed in an endothermic reaction. Not enough energy is released when products form to break more bonds in the reactants. Additional energy is needed to keep the reaction going. The general equation for an endothermic reaction is: Reactants + Energy ! Products In many endothermic reactions, heat is absorbed from the surroundings. As a result, the temperature drops. The drop in temperature may be great enough to cause liquid products to freeze. Thats what happens in the endothermic reaction at this URL: One of the most important endothermic reactions is photosynthesis. In this reaction, plants synthesize glucose (C6 H12 O6 ) from carbon dioxide (CO2 ) and water (H2 O). They also release oxygen (O2 ). The energy for photo- synthesis comes from light (see Figure 8.12). Without light energy, photosynthesis cannot occur. The chemical equation for photosynthesis is: 6CO2 + 6H2 O ! C6 H12 O6 + 6O2 In an exothermic reaction, it takes less energy to break bonds in the reactants than is released when new bonds form in the products. The word "exothermic" literally means "turning out heat." Energy, often in the form of heat, is released as an exothermic reaction occurs. The general equation for an exothermic reaction is: Reactants ! Products + Energy If the energy is released as heat, an exothermic reaction results in a rise in temperature. Thats what happens in the exothermic reaction at the URL below. Combustion reactions are examples of exothermic reactions. When substances burn, they usually give off energy as heat and light. Look at the big bonfire in Figure 8.13. You can see the light energy it is giving off. If you were standing near the fire, you would also feel its heat. Whether a reaction absorbs energy or releases energy, there is no overall change in the amount of energy. Energy cannot be created or destroyed. This is the law of conservation of energy. Energy can change form for example, from electricity to light but the same amount of energy always remains. If energy cannot be destroyed, what happens to the energy that is absorbed in an endothermic reaction? The energy is stored in the chemical bonds of the products. This form of energy is called chemical energy. In an endothermic reaction, the products have more stored chemical energy than the reactants. In an exothermic reaction, the opposite is true. The products have less stored chemical energy than the reactants. The excess energy in the reactants is released to the surroundings when the reaction occurs. The graphs in Figure 8.14 show the chemical energy of reactants and products in each type of reaction. All chemical reactions, even exothermic reactions, need a certain amount of energy to get started. This energy is called activation energy. For example, activation energy is needed to start a car. Turning the key causes a spark that activates the burning of gasoline in the engine. The combustion of gas wont occur without the spark of energy to begin the reaction. Why is activation energy needed? A reaction wont occur unless atoms or molecules of reactants come together. This happens only if the particles are moving, and movement takes energy. Often, reactants have to overcome forces that push them apart. This takes energy as well. Still more energy is needed to start breaking bonds in reactants. The graphs in Figure 8.15 show the changes in energy in endothermic and exothermic reactions. Both reactions need the same amount of activation energy in order to begin. You have probably used activation energy to start a chemical reaction. For example, if youve ever used a match to light a campfire, then you provided the activation energy needed to start a combustion reaction. Combustion is exothermic. Once a fire starts to burn, it releases enough energy to activate the next reaction, and the next, and so on. However, wood will not burst
Question: energy needed to start a reaction
[A]:
activation energy