Teacher:Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
Teacher: Now, understand the problem? Solve this instance: Abstract: The kinetics of caffeine elimination were followed in a ten month old female acutely intoxicated on a street form of the drug. Urine drug screening by gas chromatography-mass spectrometry also showed the presence of ephedrine, phenylpropanolamine, caffeine, theophylline and theobromine. Blood analyses using high pressure liquid chromatography gave evidence for the presence of theobromine, theophylline, caffeine and 1,7-dimethylxanthine. Sequentially taken blood samples determined that the initial stage of caffeine elimination was nonlinear. The Vmax = 27.6 micrograms/ml/hr and Km = 284.6 micrograms/ml. At a plasma level of approximately 30 micrograms/ml the elimination became first order with ke = 0.097 hr-1 and t 1/2 = 7.1 hr. The metabolic generation of theophylline and its elimination were also studied. Theophylline ke = 0.069 hr-1 and t 1/2 = 10.0 hr. Elimination of both drugs was anomalously long for a child of this age.
Which is the apt title for the abstract? option1: Toxicokinetics of caffeine elimination in an infant. option2: Sudden child death and 'healthy' affected family members with medium-chain acyl-coenzyme A dehydrogenase deficiency.
Student:
Toxicokinetics of caffeine elimination in an infant.