Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[EX Q]: Question: Does cYP3A5 genotype influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients?
Answer: This study provides direct and indirect evidence that CYP3A5 genotyping cannot help improve everolimus therapy.
[EX A]: no

[EX Q]: Question: Does toll-like receptor 4 signaling contribute to Paclitaxel-induced peripheral neuropathy?
Answer: The toll-like receptor TLR4 and MyD88 signaling pathway could be a new potential therapeutic target in paclitaxel-induced painful neuropathy.
[EX A]: yes

[EX Q]: Question: Does the number of axillary lymph nodes involved with metastatic breast cancer affect outcome as long as all disease is confined to the sentinel lymph nodes?
Answer: The number of nodes involved with metastatic disease does not impact OS and DFS if all disease is confined to the SLNs. Non-SLN involvement negatively influences OS and DFS independent of the number of positive nodes.
[EX A]:
no