QUES: The firm continued to pressure Kelsey and the agency to approve the applicationuntil November 1961, when the drug was pulled off the German market because of its association with grave congenital abnormalities. Several thousand newborns in Europe and elsewhere suffered the teratogenic effects of thalidomide. Though the drug was never approved in the USA, the firm distributed Kevadon to over 1,000 physicians there under the guise of investigational use. Over 20,000 Americans received thalidomide in this "study," including 624 pregnant patients, and about 17 known newborns suffered the effects of the drug.[citation needed]
Why was this drug put on shelves?

ANS: unanswerable

QUES: Unhappy with this change of policy by the Portuguese government, Napoleon sent an army to invade Portugal. On 17 October 1807, 24,000 French troops under General Junot crossed the Pyrenees with Spanish cooperation and headed towards Portugal to enforce Napoleon's orders. This attack was the first step in what would eventually become the Peninsular War, a six-year struggle that significantly sapped French strength. Throughout the winter of 1808, French agents became increasingly involved in Spanish internal affairs, attempting to incite discord between members of the Spanish royal family. On 16 February 1808, secret French machinations finally materialized when Napoleon announced that he would intervene to mediate between the rival political factions in the country. Marshal Murat led 120,000 troops into Spain and the French arrived in Madrid on 24 March, where wild riots against the occupation erupted just a few weeks later. Napoleon appointed his brother, Joseph Bonaparte, as the new King of Spain in the summer of 1808. The appointment enraged a heavily religious and conservative Spanish population. Resistance to French aggression soon spread throughout the country. The shocking French defeat at the Battle of Bailen in July gave hope to Napoleon's enemies and partly persuaded the French emperor to intervene in person.
How many troops did Marshal Murat lead into Spain?

ANS: 120,000

QUES: With the advent of the Industrial Revolution, Britain surged ahead of its European rivals. Demand for Indian commodities was boosted by the need to sustain the troops and the economy during the war, and by the increased availability of raw materials and efficient methods of production. As home to the revolution, Britain experienced higher standards of living. Its spiralling cycle of prosperity, demand and production had a profound influence on overseas trade. The company became the single largest player in the British global market. William Henry Pyne notes in his book The Microcosm of London (1808) that:
What type of material became unavailable as a result of the Industrial Revolution?

ANS: unanswerable

QUES: In 1854 president Antonio Lopez de Santa Anna enlarged the area of the Federal District almost eightfold from the original 220 to 1,700 km2 (80 to 660 sq mi), annexing the rural and mountainous areas to secure the strategic mountain passes to the south and southwest to protect the city in event of a foreign invasion. (The MexicanAmerican War had just been fought.) The last changes to the limits of the Federal District were made between 1898 and 1902, reducing the area to the current 1,479 km2 (571 sq mi) by adjusting the southern border with the state of Morelos. By that time, the total number of municipalities within the Federal District was twenty-two.
What is the current area of Mexico City?

ANS:
1,479 km2 (571 sq mi)