Given the background: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. and the situation: Uncle Tom and uncle Sam both have high cholesterol. Uncle Tom is on statin drugs and uncle Sam is not. Answer the following question: Which uncle doesn't take a drug that works slightly differently in many people?
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Answer: Sam

Q: Given the background: Other pathogens spread when they get on objects or surfaces. A fungus may spread in this way. For example, you can pick up the fungus that causes athlete's foot by wearing shoes that an infected person has worn. You can also pick up this fungus from the floor of a public shower or other damp areas. After acne, athlete's foot is the most common skin disease in the United States. Therefore, the chance of coming in contact with the fungus in one of these ways is fairly high. and the situation: Two brothers worked out a few times per week at the same gym. Tim got athlete's food from the gym, but Dan didn't. Answer the following question: Which brother picked up the fungus from the floor of a public shower?
A: Tim

Question: Given the background: Gasoline-powered vehicles emit a lot of harmful materials. Nitrogen oxides are formed when atmospheric nitrogen reacts with oxygen at the high temperatures found in a car engine. Carbon monoxide is a by-product of incomplete combustion of hydrocarbons. Evaporated and unused fuel releases volatile hydrocarbons into the atmosphere to help form smog. The presence of a catalytic converter in the exhaust system of the car causes these materials to react and be changed into less harmful products. and the situation: Hill town was full of gasoline powered vehicles, while Valley town 50 miles away, banned all gas powered vehicles and allows only electrical vehicles or horse-and-buggies. Answer the following question: Which town emitted less carbon monoxide?
Answer: Valley

[Q]: Given the background: HIV , or human immunodeficiency virus, causes AIDS. AIDS stands for "acquired immune deficiency syndrome." It is a condition that causes death and does not have a known cure. AIDS usually develops 10 to 15 years after a person is first infected with HIV. The development of AIDS can be delayed with proper medicines. The delay can be well over 20 years with the right medicines. Today, individuals who acquire HIV after 50 years of age can expect to reach an average human life span. and the situation: The police arrested two homeless people. James was 35 and had been HIV positive for 20 years, and Bill, who was 54 and was not HIV positive. They booked them and let them go. Answer the following question: Which person didn't have to take medicines to slow down the virus?
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[A]: Bill

input: Please answer the following: Given the background: Specific humidity (or moisture content) is the ratio of the mass of water vapor to the total mass of the moist air parcel.[13] Specific humidity is approximately equal to the mixing ratio, which is defined as the ratio of the mass of water vapor in an air parcel to the mass of dry air for the same parcel. As temperature decreases, the amount of water vapor needed to reach saturation also decreases. As the temperature of a parcel of air becomes lower it will eventually reach the point of saturation without adding or losing water mass. and the situation: Tho towns located on opposite banks of a river, had a humid season, but Bend town had a cooler air at night. Bank town on the other hand, had warmer nights because it was situated on a south facing hill. Answer the following question: Which town experienced a higher air temperature?
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output: Bank

Given the background: Although some lipids in the diet are essential, excess dietary lipids can be harmful. Because lipids are very high in energy, eating too many may lead to unhealthy weight gain. A high-fat diet may also increase lipid levels in the blood. This, in turn, can increase the risk for health problems such as cardiovascular disease. The dietary lipids of most concern are saturated fatty acids, trans fats, and cholesterol. For example, cholesterol is the lipid mainly responsible for narrowing arteries and causing the disease atherosclerosis. and the situation: Ronaldo and Jeff are two college roommates that have similar body structure and similar physical activity levels. Ronaldo is a nutrition enthusiast and eats a diet with appropriately low amounts of fat and cholesterol. Jeff, on the other hand, doesn't really care about nutrition at all. He eats whatever he wants, whenever he wants, and as a result he consumes a diet with an inappropriately high amount of fat and cholesterol. Answer the following question: Who is less likely to have narrowed arteries?
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Answer:
Ronaldo