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Look for times departing from the San Francisco Ferry Building and arriving in Vallejo, which will be your stop. On the weekdays, ferries run every hour or half hour, with fewer ferries running on the weekend. The ferries that depart from 4:30 pm to 6:00 pm are likely to be crowded with commuters, so buy tickets for these spots well in advance. Seating is first come first serve, so plan to arrive at least 30-45 minutes early. You can find the ferry schedule here: https://sanfranciscobayferry.com/route/sffb/vallejo You can buy your ticket at the San Francisco Ferry Building, at 1 Embarcadero, using cash or credit card. Try to buy your ticket at least 1 hour before departure, or earlier if you can. Ticket prices often change, but as of fall 2017, an adult ticket was $14.20. The Ferry Building is large, white building situated on the water just past the end of Market St. You can get there by walking, taking a taxi or ride-sharing service, or public transportation. Once in the building, follow signs for the Vallejo ferry. If you're taking the BART, get off at Embarcadero Station. If you're using MUNI, the bus service, get off at The Embarcadero and Ferry Building stop. You can also depart from Pier 41, although much fewer ferries depart from the pier than from the Ferry Building. You'll sail through the San Francisco Bay and San Pablo Bay, enjoying some great views as you go. The ride should take about an hour. Once in Vallejo, follow signs for public transportation and wait for the VINE bus to arrive. It should be plain white with "VINE" written in dark red on the side. Get on the northbound bus, which will take you along Hwy 29 and past the Napa Valley towns. Depending on when you get off, you may be riding for 1-1 hours. You can find the VINE route 11 bus schedule here: http://www.ridethevine.com/regional-routes-schedules/route-11 The public transportation route to Napa isn't structured to accommodate to tourists, but you can definitely still make it work for your purposes. Call wineries or restaurants beforehand to ask where their nearest bus stop. If you're booking tastings or other activities, give yourself a comfortable cushion in case the bus is running late - try booking a tasting about 15-30 minutes after you estimate you'll arrive.
Check the BayLink Ferry schedule. Buy a ferry ticket. Catch the ferry at the Ferry Building. Take the ferry to Vallejo. Get on the VINE bus servicing route 11. Plan to visit wineries along the bus route on the Hwy 29.