QUES: Jan Joosten van Lodensteijn (1556?1623?), a Dutch colleague of Adams' on their ill-fated voyage to Japan in the ship De Liefde, was also given similar privileges by Tokugawa Ieyasu. It appears Joosten became a samurai[citation needed] and was given a residence within Ieyasu's castle at Edo. Today, this area at the east exit of Tokyo Station is known as Yaesu (). Yaesu is a corruption of the Dutchman's Japanese name, Yayousu (). Also in common with Adam's, Joostens was given a Red Seal Ship () allowing him to trade between Japan and Indo-China. On a return journey from Batavia Joosten drowned after his ship ran aground.

Around when was Jan Joosten van Lodensteijn born?
What is the answer?
ANS: 1556
QUES: Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which hinders the entry of drugs and makes many antibiotics ineffective. The two antibiotics most commonly used are isoniazid and rifampicin, and treatments can be prolonged, taking several months. Latent TB treatment usually employs a single antibiotic, while active TB disease is best treated with combinations of several antibiotics to reduce the risk of the bacteria developing antibiotic resistance. People with latent infections are also treated to prevent them from progressing to active TB disease later in life. Directly observed therapy, i.e., having a health care provider watch the person take their medications, is recommended by the WHO in an effort to reduce the number of people not appropriately taking antibiotics. The evidence to support this practice over people simply taking their medications independently is poor. Methods to remind people of the importance of treatment do, however, appear effective.

Isoniazid is one of the two most popular drugs for TB treatment; what's the other one?
What is the answer?
ANS: rifampicin
QUES: Burke was not merely presenting a peace agreement to Parliament; rather, he stepped forward with four reasons against using force, carefully reasoned. He laid out his objections in an orderly manner, focusing on one before moving to the next. His first concern was that the use of force would have to be temporary, and that the uprisings and objections to British governance in America would not be. Second, Burke worried about the uncertainty surrounding whether Britain would win a conflict in America. "An armament", Burke said, "is not a victory". Third, Burke brought up the issue of impairment; it would do the British Government no good to engage in a scorched earth war and have the object they desired (America) become damaged or even useless. The American colonists could always retreat into the mountains, but the land they left behind would most likely be unusable, whether by accident or design. The fourth and final reason to avoid the use of force was experience; the British had never attempted to rein in an unruly colony by force, and they did not know if it could be done, let alone accomplished thousands of miles away from home. Not only were all of these concerns reasonable, but some turned out to be prophetic the American colonists did not surrender, even when things looked extremely bleak, and the British were ultimately unsuccessful in their attempts to win a war fought on American soil.

How many reasons in favor of the use of force did Burke present?
What is the answer?
ANS:
unanswerable