instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
The Lambro (Western Lombard: Lamber or Lambar) is a river of Lombardy, northern Italy, a left tributary of the Po.
answer:
What river is Lambro a tributary of?

question:
Chronic myeloid leukemia (CML) is characterized by the Philadelphia translocation that fuses BCR sequences from chromosome 22 upstream of the ABL gene on chromosome 9. The chimerical Bcr-Abl protein expressed by CML cells has constitutive tyrosine kinase activity, which is essential for the pathogenesis of the disease. Imatinib, an ATP-competitive selective inhibitor of Bcr-Abl, has unprecedented efficacy for the treatment of CML. Most patients with early stage disease achieve durable complete hematological and complete cytogenetic remissions, with minimal toxicity. In contrast, responses are less stable in patients with advanced CML. This review highlights the pathogenesis of CML, its clinical features, and the development of imatinib as a specific molecularly targeted therapy. Aspects of disease monitoring and side effects are covered as well as resistance to imatinib and strategies to overcome resistance, such as alternative signal transduction inhibitors and drug combinations. Perspectives for further development are also discussed.
answer:
What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

question:
Coming off a two-game winning streak, the Broncos headed to Lucas Oil Stadium to play the undefeated Colts. In the first half, the Colts jumped out to a 21-0 lead. Denver finally scored when Kyle Orton found Brandon Marshall in the end zone going to the locker rooms trailing 21-7. For most of the second half, the Colts offense sputtered. In a long drive, Orton found Marshall for his second touchdown, however, the two-point conversion was no good, making the score 21-16. Then the Colts offense got things going late in the fourth. After a long drive, Manning found Dallas Clark in the end zone for his third touchdown of the day, putting the Colts on top 28-16 with under three minutes left in the game. On a long fourth down, Orton found Marshall who lateraled the ball to a lineman who was tackled short of the first down. With the win, the Colts broke an NFL record with 23 straight wins. Though despite the loss, Broncos WR Brandon Marshall had a record of his own with 21 catches beating Terrell Owens' record.
answer:
Which team member also broke a record?