In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: Of the following reaction mechanisms, in which there is an inversion of the configuration from the reactant to the product of the reaction ?:
Options: <1> Bimolecular nucleophilic substitution (SN2). <2> Unimolecular elimination (E1). <3> Unimolecular nucleophilic substitution (SN1). <4> Addition Markovnikov. <5> Addition anti-Markovnikov.
[A]: 1

[Q]: Question: One of the following is NOT a guideline that should guide interventions in Autism Spectrum Disorders. Point out which:
Options: <1> Use personalized teaching programs based on an evolutionary framework. <2> Intervene in a group setting to favor the acquisition of social skills. <3> Intervene in highly structured and predictable contexts. <4> Use learning procedures without mistakes. <5> Favor motivation.
[A]: 2

[Q]: Question: The content validity of an evaluation instrument refers to:
Options: <1> The evidence obtained by factor analysis. <2> The concurrence of measures. <3> The adequacy in the establishment of inferences. <4> The relevance and representativeness of its items. <5> The significant relationships with other measures.
[A]:
4