instruction:
Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).
question:
Abstract: Blood flow through and chlormethiazole extraction ratios across lungs, liver, kidneys and gut were measured in awake unrestrained sheep (controls) and with the same animals anaesthetized with 1.5% halothane or whilst undergoing high thoracic subarachnoid blockade with amethocaine. In the control-drug studies, chlormethiazole infused to sub-sedative blood concentrations produced no significant changes in haemodynamics or in the kinetics of iodohippurate (renal and hepatic blood flows). Chlormethiazole was eliminated predominantly by the liver (mean extraction ratio and clearance, respectively, 0.90 and 1.3 litre min-1) and lungs (0.15; 0.6 litre min-1). Renal clearance was absent or negligible (greater than 0.1 litre min-1). Because of pulmonary clearance, mean total body clearance was derived from analysis of pulmonary arterial concentrations. Under general anaesthesia, there were significant reductions in mean cardiac output, hepatic and renal blood flow (to 54%, 63% and 43% of control); chlormethiazole mean hepatic extraction ratios and clearance were reduced, respectively, to 82% and 56% of control, and its pulmonary and renal clearances were abolished. With subarachnoid anaesthesia there were no significant changes in haemodynamics or in chlormethiazole extraction ratios or clearances.
Which is the apt title for the abstract? option1: A sheep preparation for studying interactions between blood flow and drug disposition. VI: Effects of general or subarachnoid anaesthesia on blood flow and chlormethiazole disposition. option2: Medium-depth chemical peeling: digging beneath the surface [editorial]
answer:
A sheep preparation for studying interactions between blood flow and drug disposition. VI: Effects of general or subarachnoid anaesthesia on blood flow and chlormethiazole disposition.

question:
Abstract: A retrospective epidemiological study of industrial burns admitted to the Royal Brisbane Hospital was conducted over a period of 7 years. A total of 182 patients were included in this survey--173 males (95 per cent) and 9 females (5 per cent). The proportion of industrial burns has decreased from 31.5 per cent to 18.5 per cent of total admissions to the burns unit over the past 10 years. Fifty per cent of the burns occurred in males less than 30 years old. The average age was 31 years. Two-thirds of the burns covered less than 10 per cent of the body and 84 per cent covered less than 20 per cent. While scalds were the commonest cause of industrial burns in our study (19.4 per cent), flame burns with clothing ignited caused the most extensive burns. Face and hands were the most common sites involved. Burns to these regions were mainly caused by flame and electrical burns. Eye burns comprised 5.5 per cent of the sample and were due to chemicals, gas explosions and electric flash. Twenty-six patients (14 per cent) suffered respiratory injury. Only one patient out of our series of 182 died. Progress has been made in industrial safety in the past few years but carelessness and human error still take their toll.
Which is the apt title for the abstract? option1: Epidemiology of industrial burns in Brisbane. option2: Epidemiologic and socioeconomic aspects of allergic diseases.
answer:
Epidemiology of industrial burns in Brisbane.

question:
Abstract: Neutron Activation Analysis (NAA) was used to investigate trace element patterns in serum, packed cells, and dialysate of CAPD patients. The concentrations of the elements Cs, Cu, Fe, and Mn in serum and packed cells appeared to be maintained within the normal range, while the levels of the non-essential element Br in both serum and packed cells were subnormal. The serum Cr values were extremely high (20 to 50 times higher than the normal serum level). The amount of Cr absorbed from the dialysate was calculated to be ten times higher than the daily dietary uptake. The Co concentrations were normal in packed cells but were significantly increased in serum. The Rb content in packed cells was slightly lower than normal, while the serum value was normal. Se was maintained within the normal range in packed cells, but the serum concentration was slightly lower than normal. The concentrations of Zn were low in serum and appeared to be higher than normal in packed cells. In conclusion, this analysis of the trace element status of CAPD patients reveals two major abnormalities. There is an apparent loss of Br from the blood towards the dialysate and on the other hand, a dramatic accumulation of Cr into the blood as a result of the very high Cr content in the dialysate.
Which is the apt title for the abstract? option1: Trace elements in serum, packed cells, and dialysate of CAPD patients. option2: Are the holidays hazardous to your patients' health? [editorial]
answer:
Trace elements in serum, packed cells, and dialysate of CAPD patients.