Managers in the Premier League are involved in the day-to-day running of the team, including the training, team selection, and player acquisition. Their influence varies from club-to-club and is related to the ownership of the club and the relationship of the manager with fans. Managers are required to have a UEFA Pro Licence which is the final coaching qualification available, and follows the completion of the UEFA 'B' and 'A' Licences. The UEFA Pro Licence is required by every person who wishes to manage a club in the Premier League on a permanent basis (i.e. more than 12 weeks the amount of time an unqualified caretaker manager is allowed to take control). Caretaker appointments are managers that fill the gap between a managerial departure and a new appointment. Several caretaker managers have gone on to secure a permanent managerial post after performing well as a caretaker; examples include Paul Hart at Portsmouth and David Pleat at Tottenham Hotspur.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What is a manager appointment?
Ah, so.. unanswerable

Antibiotics revolutionized medicine in the 20th century, and have together with vaccination led to the near eradication of diseases such as tuberculosis in the developed world. Their effectiveness and easy access led to overuse, especially in livestock raising, prompting bacteria to develop resistance. This has led to widespread problems with antimicrobial and antibiotic resistance, so much as to prompt the World Health Organization to classify antimicrobial resistance as a "serious threat [that] is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country".
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What happened when antibiotics was over used in livestock?
Ah, so.. develop resistance

The show pushed Fox to become the number one U.S. TV network amongst adults 1849, the key demographic coveted by advertisers, for an unprecedented eight consecutive years by 2012. Its success also helped lift the ratings of other shows that were scheduled around it such as House and Bones, and Idol, for years, had become Fox's strongest platform primetime television program for promoting eventual hit shows of the 2010s (of the same network) such as Glee and New Girl. The show, its creator Simon Fuller claimed, "saved Fox".
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What television network originally aired the show Glee?
Ah, so..
Fox