Q: Given a scientific passage and an answer, generate a question for the given answer.
Passage: Vesicles are much smaller than vacuoles and have a variety of functions. Some vesicles pinch off from the membranes of the endoplasmic reticulum and Golgi apparatus. These vesicles store and transport proteins and lipids. Other vesicles are used as chambers for biochemical reactions. Answer: smaller
A:
Are vesicles larger or smaller than vacuoles?