Here is a question about this article: Obesity can unfavourably alter hormonal and metabolic status via resistance to the hormone leptin, and a vicious cycle may occur in which insulin/leptin resistance and obesity aggravate one another. The vicious cycle is putatively fuelled by continuously high insulin/leptin stimulation and fat storage, as a result of high intake of strongly insulin/leptin stimulating foods and energy. Both insulin and leptin normally function as satiety signals to the hypothalamus in the brain; however, insulin/leptin resistance may reduce this signal and therefore allow continued overfeeding despite large body fat stores. In addition, reduced leptin signalling to the brain may reduce leptin's normal effect to maintain an appropriately high metabolic rate.
What is the answer to this question: What function do insulin and leptin normally provide in the body?
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So... satiety signals to the hypothalamus

Here is a question about this article: Kinnock then resigned as leader and was replaced by John Smith. Smith's leadership once again saw the re-emergence of tension between those on the party's left and those identified as "modernisers", both of whom advocated radical revisions of the party's stance albeit in different ways. At the 1993 conference, Smith successfully changed the party rules and lessened the influence of the trade unions on the selection of candidates to stand for Parliament by introducing a one member, one vote system called "OMOV" but only barely, after a barnstorming speech by John Prescott which required Smith to compromise on other individual negotiations.
What is the answer to this question: Who replaced Kinnock?
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So... John Smith

Here is a question about this article: In 1953, Korolev was given the go-ahead to develop the R-7 Semyorka rocket, which represented a major advance from the German design. Although some of its components (notably boosters) still resembled the German G-4, the new rocket incorporated staged design, a completely new control system, and a new fuel. It was successfully tested on August 21, 1957 and became the world's first fully operational ICBM the following month. It would later be used to launch the first satellite into space, and derivatives would launch all piloted Soviet spacecraft.
What is the answer to this question: When was the R-7 Semyorka rocket tested successfully?
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So...
August 21, 1957