In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: The main indication for using 4 drugs in the initial treatment of tuberculosis is:
Options: <1> Affectation of the central nervous system. <2> High prevalence of primary resistance to isoniazid. <3> Cavitated and extensive pulmonary tuberculosis with large bacillary load. <4> Disseminated tuberculosis associated with HIV infection. <5> Extrapulmonary tuberculosis in immunodepressed patients of any origin.
[A]: 2

[Q]: Question: Indicate which of the following statements is true about bilirubin:
Options: <1> It is a catabolic product of the heme group. <2> It is a product of the urea cycle. <3> It is an intermediary of the Krebs cycle. <4> It is a precursor of hepatic gluconeogenesis. <5> It is a product of cholesterol degradation.
[A]: 1

[Q]: Question: Allopurinol, as an inhibitor of xanthine oxidase:
Options: <1> It is suicidal, reversible. <2> It is suicidal, irreversible. <3> It is analogous to the transition state, reversible. <4> Inhibits the enzyme by proteolysis. <5> Allopurinol does not inhibit that enzyme.
[A]:
2