Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: What happens inside the skull of a soccer player who repeatedly heads a soccer ball? That question motivate a challenging new study of the brains of experienced players that has caused discussion and debate among soccer players, and some anxiety among those of us with soccer-playing children. For the study, researchers at the Albert Einstein College of Medicine in New York selected 34 adults,men and women. All of the volunteers had played soccer since childhood and now competed year-round in adult soccer leagues. Each filled out a detailed questionnaire developed especially for this study to determine how many times they had headed a soccer ball in the previous year, as well as whether they had experienced any known concussions in the past. Then the players completed computerized tests of their memory and other learning skills and had their brains scanned, using a complicated new MRI technique which can find structural changes in the brain that can't be seen during most scans. According to the data they presented at a Radiological Society of North America meeting last month,the researchers found that the players who had headed the ball more than about 1,100 times in the previous 12 months showed significant loss of white matter in parts of their brains involved with memory,attention and the processing of visual information, compared with players who had headed the ball fewer times. This pattern of white matter loss is "similar to those seen in traumatic brain injury" , like that after a serious concussion, the researchers reported,even though only one of these players was reported to have ever experienced a conc ussion. The players who had headed the ball about 1,100 times or more in the past year were also generally worse at recalling lists of words read to them, forgetting or _ the words far more often than players who had headed the ball less.
[A]: What is likely to be the cause of memory loss?

[Q]: What could make Michael Jordon, one of the greatest basketball players in history, shed tears? It was when he became a member of the Basketball Hall of Fame on September 11. The hall is in Springfield, Massachusetts and honors the best basketball players, greatest coaches and other contributors to the game. "The game of basketball has been everything to me ," said Jordan, 46. "It is the place I have always gone when I needed to find comfort and peace." Jordan retired twice in his 15-year career, finishing with 32292 points, the third highest total points in NBA history behind Kareem Abdul-Jabbar and Karl Malone. His average of 30.12 points a game is the best in the League. "One day you might look up and see me playing the game at 50," Jordan said. "Because limits, like fears, are often just an illusion." In other words, it was motivation that made Jordan such a success.. A great career did not mean a smooth one. His high school coach cut him from the team in favor of a taller player when Jordan was in 10thgrade. His college coach wouldn't allow him on the cover of Sports Illustration in 1981 with North Carolina's four other players because Jordan was a freshman. In his first NBA All-Star game, older NBA stars wouldn't throw him the ball because of jealousy. "That burned me up," Jordan said. "But _ don't have to stop you. If you run into a wall, don't turn around and give up. Figure out how to climb it, go through it, or work around it."
[A]: Who scored the highest total points in NBA history?

[Q]: Epidermal growth factor receptor (EGFR) gene mutations have been found in a subset of non-small cell lung cancer (NSCLC) with good clinical response to gefitinib therapy. A quick and sensitive method with large throughput is required to utilize the information to determine whether the molecular targeted therapy should be applied for the particular NSCLC patients. Using probes for the 13 different mutations including 11 that have already been reported, we have genotyped the EGFR mutation status in 94 NSCLC patients using the TaqMan PCR assay. We have also genotyped the EGFR mutations status in additional 182 NSCLC patients, as well as 63 gastric, 95 esophagus and 70 colon carcinoma patients. In 94 NSCLC samples, the result of the TaqMan PCR assay perfectly matched with that of the sequencing excluding one patient. In one sample in which no EGFR mutation was detected by direct sequencing, the TaqMan PCR assay detected a mutation. This patient was a gefitinib responder. In a serial dilution study, the assay could detect a mutant sample diluted in 1/10 with a wild-type sample. Of 182 NSCLC samples, 46 mutations were detected. EGFR mutation was significantly correlated with gender, smoking status, pathological subtypes, and differentiation of lung cancers. There was no mutation detected by the TaqMan PCR assay in gastric, esophagus and colon carcinomas. TaqMan PCR assay is a rapid and sensitive method of detection of EGFR mutations with high throughput, and may be useful to determine whether gefitinib should be offered for the treatment of NSCLC patients. The TaqMan PCR assay can offer us a complementary and confirmative test.
[A]:
Mutations in which gene determine response to both erlotinib and gefitinib?