Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does metoclopramide influence the frequency of propofol-induced spontaneous movements?
Answer: Metoclopramide does not affect the frequency of propofol-induced movements, but propofol and fentanyl doses influence the frequency of movements during propofol induction.

Answer: no

Question: Question: Is cytoglobin upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer?
Answer: We conclude that the CYGB gene is regulated by both promoter methylation and tumour hypoxia in HNSCC and that increased expression of this gene correlates with clincopathological measures of a tumour's biological aggression.

Answer: yes

Question: Question: Is mid-gestation pregnancy disrupted by a 5-day gastrointestinal mucosal cytoprotectant oral regimen of misoprostol?
Answer: Treatment of pregnant mares with a gastrointestinal mucosal cytoprotectant regimen of oral misoprostol for 5 days did not disrupt pregnancy, nor adversely affect the general health and comfort of these mares. Additional investigation of treatment at earlier and later stages of gestation, for longer-term treatment, as well as evaluating neonates for developmental disturbances, would add further information on safety of misoprostol during gestation.

Answer:
no