What key details about michael ristow can be extracted from the following bio? Bio: michael ristow -lrb- b april 24 , 1967 -rrb- is a german medical researcher who has published influential articles on biochemical aspects of mitochondrial metabolism and particularly the possibly health-promoting role of reactive oxygen species in diseases like type 2 diabetes , obesity and cancer , as well as general aging due to a process called mitohormesis . ristow was born in lubeck in the north of germany . he graduated at the university of bochum in 1992 and received his m.d. from university of bochum in 1996 . he was appointed to the university of jena in 2005 as a full professor in nutritional science , and is a full professor in energy metabolism at the eth zurich since 2013 . in 2007 , ristow 's group published evidence which could explain the basis of the observed extension of lifespan by restriction of sugar intake . in experiments on a model organism , the worm caenorhabditis elegans , they found that lowering the availability of glucose extended the lifespan of the worms . it has been known since the 1930s that restricting calories while maintaining adequate amounts of other nutrients extends lifespan across a broad range of organisms . the mechanism has been proposed as a change in the activity of the sirtuins . michael ristow shows in his article that this effect can also occur independent of sirtuins , since worms deficient for sirtuins still show extended life span in states of sugar restriction . most importantly , ristow 's research suggests that this is a mitohormetic effect , as reviewed in . hormesis is a controversial concept in which it has been demonstrated that the induction of a stress can lengthen lifespan in some species . ristow 's interpretation was that in response to a decrease in glycolytic energy production , the worms have to generate atp by oxidative phosphorylation in the mitochondria , leading to increased production of reactive oxygen species . due to a vacination-like response , the organism produces more defenses against oxidative stress , including increased...
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- known for is mitohormesis , mitochondrial metabolism- work institutions is eth harvard university , cambridge joslin diabetes center , boston university zurich of cologne , germany , switzerland university of jena , germany- field is biochemistry- birth date is 24 april 1967- name is michael ristow- nationality is german- birth place is lubeck , germany- alma mater is ruhr university bochum , germany