Given the task definition and input, reply with output. Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

The cost of MDMA is not mentioned, and likely difficult to forecast. However, the associated therapy is fairly intensive, and it remains to be seen if it would be covered by insurance. Still, a discussion of these potentially significant costs would have been relevant and helpful, even if the story admits they're largely unknown. We're told that after two sessions of MDMA-assisted psychotherapy a majority of 26 combat veterans and first-responders with chronic PTSD (who had not been helped by traditional methods) saw dramatic decreases in symptoms. The improvements were so dramatic that 68 percent of the patients no longer met the criteria for PTSD. Patients taking the drug also experienced "drastic" improvements in sleep and become more conscientious, according to the study. This is enough to rate Satisfactory, but we think the story needed more details on how the study was designed to help readers understand this result (see evidence quality, below). The article states: Side effects including anxiety, headache, fatigue, muscle tension, and insomnia, were generally minor and limited to the days following the MDMA sessions. Readers might have concerns regarding the long-term consequences of pharmaceutical grade MDMA, but this is unknown. The article does make it clear that the MDMA-assisted psychotherapy model used in the study only involves taking the drug on 2-3 occasions. Also, the article anticipates that some people may (and already do) turn to street sources of MDMA (aka "Ecstasy" or "Molly") to self medicate. It's made clear that this could could be dangerous, or even fatal, since street sources can be laced with other psychoactive drugs. In an otherwise comprehensive article, there's room for improvement here. We're told a limited amount about the study design; in particular the questionnaire (called "CAPS-IV") used to measure response in this small group of people. So we have little context with which to understand this outcome: Roughly 2 out of 3 subjects no longer meeting the criteria for PTSD. Also, there's the issue of the reliability and reproducibility of questionnaires that rely upon the self-reporting of symptoms. Having said that, the article does well to ask: But does it actually work? Large-scale trials, which will include up to 300 participants at 14 sites, may not be able to replicate the success of previous trials, which were limited to a few dozen patients. Lastly, in an editorial that ran in the same issue of the Lancet, the editorialists also make the point that the participants were recruited via the internet and word of mouth, potentially skewing towards those "keen" on trying ecstasy. None. PTSD is fairly common and moderate to severe cases often prove difficult to treat. The unique funding for this project, as well as "who cashes in if MDMA becomes legal" is thoroughly covered and a very nice addition to the article. The lead authors appear to have no financial conflicts of interest, and multiple sources were tapped. The answer is revealing; essentially current interventions mostly psychotherapy and/or drugs have been mostly ineffective. It's made clear that MDMA "is about to enter larger Phase III trials," the FDA has granted pharmaceutical grade MDMA breakthrough therapy status, and that illegal sources exist but are potentially dangerous. It's also mentioned that there have already been several other small-scale studies of the drug, and that if MDMA is eventually approved by the FDA it will only be administered by a licensed therapist. We did have one quibblethe story predicts that, if larger studies go well, the drug could be approved for this use "by 2021." In reality, there's really no way of knowing what year a drug will get approved. In the section "Is MDMA therapy new?" we learn that MDMA-assisted psychotherapy has been both formally, and informally, used in the past. The story did not rely on the news release.
Ecstasy as PTSD Relief for Soldiers: 'I Was Able to Forgive Myself'