Q: Given a scientific passage and an answer, generate a question for the given answer.
Passage: A mutation may have no effect. However, sometimes a mutation can cause a protein to be made incorrectly. A defect in the protein can affect how well the protein works, or whether it works at all. Usually the loss of a protein function is detrimental to the organism. Answer: mutation
A:
What phenomenon can cause a protein in an organism to be made incorrectly?