Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: When the order was restored, Murad Pasha marched against Abbas I who was in Tabriz in 1610. Although the two armies met in Accay, north of Tabriz, no engagement or action took place. Due to the problems in the logistics, supply chain and the approaching winter Murad Pasha withdrew his forces to Diyarbakr. While being engaged in diplomatic correspondence with Abbas I for peace and preparing his army for another campaign at the same time he died on 5 August 1611 when he was older than 90. Nasuh Pasha was appointed as the new grand vizier and the commander of the eastern armies. He sued for peace, too, and accepted the proposal of the Safevid side in 1611. The Treaty of Nasuh Pasha was signed on 20 November 1612. The agreement secured the 1555 borders envisaged by the Peace of Amasya. Shah Abbas however, committed himself to send 200 bales of raw silk annually.
Example Output: Which happened first, Murad marching against Abbas or the signing of the Treaty of Nasuh Pasha?

Example Input: SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene transcription. We solved the structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in their apo conformation or in complex with the methyl donating cofactor, and peptide substrates. We analyzed the structural determinants for methylation state specificity, and designed a G9a mutant able to tri-methylate H3K9. We show that the I-SET domain acts as a rigid docking platform, while induced-fit of the Post-SET domain is necessary to achieve a catalytically competent conformation. We also propose a model where long-range electrostatics bring enzyme and histone substrate together, while the presence of an arginine upstream of the target lysine is critical for binding and specificity. This article can also be viewed as an enhanced version in which the text of the article is integrated with interactive 3D representations and animated transitions. Please note that a web plugin is required to access this enhanced functionality. Instructions for the installation and use of the web plugin are available in Text S1.
Example Output: What is the characteristic domain of histone methyltransferases?

Example Input: The Get Up Kids are an American rock band from Kansas City, Missouri.
Example Output:
What city was The Get Up Kids formed in?