Input: Article: Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.

Now answer this question: What discovery caused the model that one gene makes one protein to be refined?

Output: the discovery of genes that can encode multiple proteins

Input: Article: Interstate 40 crosses the state in a west-east orientation. Its branch interstate highways include I-240 in Memphis; I-440 in Nashville; I-140 from Knoxville to Alcoa and I-640 in Knoxville. I-26, although technically an east-west interstate, runs from the North Carolina border below Johnson City to its terminus at Kingsport. I-24 is an east-west interstate that runs cross-state from Chattanooga to Clarksville. In a north-south orientation are highways I-55, I-65, I-75, and I-81. Interstate 65 crosses the state through Nashville, while Interstate 75 serves Chattanooga and Knoxville and Interstate 55 serves Memphis. Interstate 81 enters the state at Bristol and terminates at its junction with I-40 near Dandridge. I-155 is a branch highway from I-55. The only spur highway of I-75 in Tennessee is I-275, which is in Knoxville. When completed, I-69 will travel through the western part of the state, from South Fulton to Memphis. A branch interstate, I-269 also exists from Millington to Collierville.

Now answer this question: What Tennessee cities are connected by I-269?

Output: Millington to Collierville

Input: Article: A person's self-report is the most reliable measure of pain, with health care professionals tending to underestimate severity. A definition of pain widely employed in nursing, emphasizing its subjective nature and the importance of believing patient reports, was introduced by Margo McCaffery in 1968: "Pain is whatever the experiencing person says it is, existing whenever he says it does". To assess intensity, the patient may be asked to locate their pain on a scale of 0 to 10, with 0 being no pain at all, and 10 the worst pain they have ever felt. Quality can be established by having the patient complete the McGill Pain Questionnaire indicating which words best describe their pain.

Now answer this question: What is the most reliable measure of pain?

Output:
person's self-report