Detailed Instructions: In this task, you are given an abstract of article. Your task is to generate title for this article. Preferred titles are under thirty words.
Problem:Early views of autoimmune disease cast IFN as a prototypic pro-inflammatory factor. It is now clear that IFN is capable of both pro- and anti-inflammatory activities with the functional outcome dependent on the physiological and pathological setting examined. Here, the major immune modulatory activities of IFN are reviewed and current evidence for the impact of IFN on pathology and regulation of several autoimmune diseases and disease models is summarized.
Solution:
Interferon gamma in autoimmunity: A complicated player on a complex stage.