Given the task definition and input, reply with output. Given a scientific passage and an answer, generate a question for the given answer.

Passage: The tRNA structure is a very important aspect in its role. Though the molecule folds into a 3-leaf clover structure, notice the anticodon arm in the lower segment of the molecule, with the amino acid attached at the opposite end of the molecule (acceptor stem). It is the anticodon that determines which codon in the mRNA the tRNA will bind to. Answer: anticodon
What determines which codon in the mrna the trna will bind to?