Definition: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: Indicate which of the following is an alteration of the pyrimidine metabolism:
Options: <1> Thrombophilia <2> Phenylketonuria <3> Wilson's disease <4> Urine disease with the smell of maple syrup. <5> Orotic hereditary acidity.
Output:
5