Ans: neutralize pathogens such as pathogenic bacteria and viruses
Ques: An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen, via the Fab's variable region. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (similarly analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly (for example, by blocking a part of a microbe that is essential for its invasion and survival). Depending on the antigen, the binding may impede the biological process causing the disease or may activate macrophages to destroy the foreign substance. The ability of an antibody to communicate with the other components of the immune system is mediated via its Fc region (located at the base of the "Y"), which contains a conserved glycosylation site involved in these interactions. The production of antibodies is the main function of the humoral immune system.

Based on this passage, what is the role of antibodies in the immune response?
CoT: The relevant information to answer the above question is: An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

Ans: enterprise resource planning software developed by the German company SAP SE
Ques: SAP ERP is enterprise resource planning software developed by the German company SAP SE. SAP ERP incorporates the key business functions of an organization. The latest version (SAP ERP 6.0) was made available in 2006. The most recent Enhancement Package (EHP8) for SAP ERP 6.0 was released in 2016.

Answer this question: what is the meaning of sap erp system?
CoT: The important part for answering this question is: SAP ERP is enterprise resource planning software developed by the German company SAP SE.

Answer: Dylan Thomas. Now, what could be the question and solution-maybe?
Ques: "Do not go gentle into that good night" is a poem in the form of a villanelle, and the most famous work of Welsh poet Dylan Thomas (1914 -- 1953). Though first published in the journal Botteghe Oscure in 1951, it was written in 1947 when he was in Florence with his family. It was published, along with other stories previously written, as part of his In Country Sleep, And Other Poems in 1952.

Based on this passage, who said do not go gentle into that good night?
CoT: The relevant information to answer the above question is: "Do not go gentle into that good night" is a poem in the form of a villanelle, and the most famous work of Welsh poet Dylan Thomas (1914 -- 1953).

Ans: Alvin Lee
Ques: Context: Alvin Lee -- guitar and vocals Leo Lyons -- bass Ric Lee -- drums Chick Churchill -- keyboards

Question: who sang i want to change the world?
CoT: The relevant information to answer the above question is: Alvin Lee -- guitar and vocals Leo Lyons -- bass

Ans: secondary lymphoid organs such as the spleen and the lymph nodes
Ques: The theory states that in a pre-existing group of lymphocytes (specifically B cells), a specific antigen only activates (i.e. selection) its counter-specific cell so that particular cell is induced to multiply (producing its clones) for antibody production. This activation occurs in secondary lymphoid organs such as the spleen and the lymph nodes. In short the theory is an explanation of the mechanism for the generation of diversity of antibody specificity. The first experimental evidence came in 1958, when Gustav Nossal and Joshua Lederberg showed that one B cell always produces only one antibody. The idea turned out to be the foundation of molecular immunology, especially in adaptive immunity.

Answer this question: where does clonal selection of t cells happen?
CoT: To answer the above question, the relevant sentence is: This activation occurs in secondary lymphoid organs such as the spleen and the lymph nodes.

Answer: north - northwest of London. Now, what could be the question and solution-maybe?
Ques: Passage: Leeds is located 190 miles (310 km) north-northwest of London, on the valley of the River Aire in the eastern foothills of the Pennines. The city centre lies in a narrow section of the Aire Valley at about 206 feet (63 m) above sea level; while the district ranges from 1,115 feet (340 m) in the far west on the slopes of Ilkley Moor to about 33 feet (10 m) where the rivers Aire and Wharfe cross the eastern boundary. The centre of Leeds is part of a continuously built-up area extending to Pudsey, Bramley, Horsforth, Alwoodley, Seacroft, Middleton and Morley.

Question: Based on this passage, is leeds in the north west or north east?
CoT: To answer the above question, the relevant sentence is: Leeds is located 190 miles (310 km) north-northwest of London, on the valley of the River Aire in the eastern foothills of the Pennines.