instruction:
In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
question:
Paragraph: Influenza virus entry is mediated by the receptor binding domain (RBD) of its spike, the hemagglutinin (HA). Adaptation of avian viruses to humans is associated with HA specificity for 2,6rather than 2,3-linked sialic acid (SA) receptors. Here, we define mutations in influenza A subtype H5N1 (avian) HA that alter its specificity for SA either by decreasing 2,3or increasing 2,6-SA recognition. RBD mutants were used to develop vaccines and monoclonal antibodies that neutralized new variants. Structure-based modification of HA specificity can guide the development of preemptive vaccines and therapeutic monoclonal antibodies that can be evaluated before the emergence of human-adapted H5N1 strains.
Title: Immunization by Avian H5 Influenza Hemagglutinin Mutants with Altered Receptor Binding Specificity
answer:
True

question:
Paragraph: In the past years, network theory has successfully characterized the interaction among the constituents of a variety of complex systems, ranging from biological to technological, and social systems. However, up until recently, attention was almost exclusively given to networks in which all components were treated on equivalent footing, while neglecting all the extra information about the temporal-or context-related properties of the interactions under study. Only in the last years, taking advantage of the enhanced resolution in real data sets, network scientists have directed their interest to the multiplex character of real-world systems, and explicitly considered the time-varying and multilayer nature of networks. We offer here a comprehensive review on both structural and dynamical organization of graphs made of diverse relationships (layers) between its constituents, and cover several relevant issues, from a full redefinition of the basic structural measures, to understanding how the multilayer nature of the network affects processes and dynamics.
Title: The structure and dynamics of multilayer networks
answer:
True

question:
Paragraph: Background: As the outbreak of Coronavirus disease 2019 (COVID-19) is a worldwide pandemic, and it is rapidly expanding in Iran, real-time analyses of epidemiological data are needed to increase situational awareness and inform interventions. In this study, we built a predictive model based on the cumulative trend of new cases and deaths for the top five provinces. We will also look at modeling the trends for confirmed cases, deaths and recovered for the whole country. Method: In this study, we have chosen to apply the exponential smoothing model to iteratively forecast future values of a regular time series from weighted averages of past daily values. This method is exponential because the value of each level is influenced by every preceding actual value to an exponentially decreasing degree -more recent values are given greater weight. The available data is too small to identify seasonal patterns and make a predictable variation in value, such as annual fluctuation in temperature related to the season. The trend is a tendency of the data to increase or decrease over time.
Title: Title: Modeling the Corona Virus Outbreak in IRAN
answer:
True