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Both of the guidebooks I've looked at suggest starting in Milan and traveling through Verona and Dolomites to get to Venice, then swing down to Florence. I won't be seeing Florence or Tuscany, so I was wondering if there were any particular reasons why I shouldn't go from Venice to Milan.

My total trip length for Northern Italy is about 10-15 days (haven't solidified my schedule yet) and I plan to begin the trip in mid-October. I thought if I started in Venice, I would have a better chance of avoiding acqua alta (floods) as I have read they happen most often in November and December -- as opposed to having it start at the end of the trip, which would be into November or late October. However, I don't know if the reason why the guidebooks suggest doing so is because it is cheaper to fly into Milan instead.

My next destination from Italy is the Czech Republic.
Northern Italy: east to west or west to east?