instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
A rocket is propelled into space by particles flying out of one end at high speed (see Figure 1.1). A rocket in space moves like a skater holding the fire extinguisher. Fuel is ignited in a chamber, which causes an explosion of gases. The explosion creates pressure that forces the gases out of the rocket. As these gases rush out the end, the rocket moves in the opposite direction, as predicted by Newtons Third Law of Motion. The reaction force of the gases on the rocket pushes the rocket forward. The force pushing the rocket is called thrust. Nothing would get into space without being thrust upward by a rocket. One of the first uses of rockets in space was to launch satellites. A satellite is an object that orbits a larger object. An orbit is a circular or elliptical path around an object. The Moon was Earths first satellite, but now many human- made "artificial satellites" orbit the planet. Thousands of artificial satellites have been put into orbit around Earth (Figure 1.2). We have even put satellites into orbit around the Moon, the Sun, Venus, Mars, Jupiter, and Saturn. There are four main types of satellites. Imaging satellites take pictures of Earths surface for military or scientific purposes. Imaging satellites study the Moon and other planets. Communications satellites receive and send signals for telephone, television, or other types of communica- tions. Navigational satellites are used for navigation systems, such as the Global Positioning System (GPS). The International Space Station, the largest artificial satellite, is designed for humans to live in space while conducting scientific research. Humans have a presence in space at the International Space Station (ISS) (pictured in Figure 1.3). Modern space stations are constructed piece by piece to create a modular system. The primary purpose of the ISS is scientific research, especially in medicine, biology, and physics. Craft designed for human spaceflight, like the Apollo missions, were very successful, but were also very expensive, could not carry much cargo, and could be used only once. To outfit the ISS, NASA needed a space vehicle that was reusable and able to carry large pieces of equipment, such as satellites, space telescopes, or sections of a space station. The resulting spacecraft was a space shuttle, shown in (Figure 1.4). Satellites operate with solar panels for energy. A photograph of the International Space Station was taken from the space shuttle Atlantis in June 2007. Construction of the station was completed in 2011, but new pieces and experiments continue to be added. A space shuttle has three main parts. The part you are probably most familiar with is the orbiter, with wings like an airplane. When a space shuttle launches, the orbiter is attached to a huge fuel tank that contains liquid fuel. On the sides of the fuel tank are two large "booster rockets." All of this is needed to get the orbiter out of Earths atmosphere. Once in space, the orbiter can be used to release equipment (such as a satellite or supplies for the International Space Station), to repair existing equipment such as the Hubble Space Telescope, or to do experiments directly on board the orbiter. When the mission is complete, the orbiter re-enters Earths atmosphere and flies back to Earth more like a glider than an airplane. The Space Shuttle program did 135 missions between 1981 and 2011, when the remaining shuttles were retired. The ISS is now serviced by Russian Soyuz spacecraft. Atlantis on the launch pad in 2006. Since 1981, the space shuttle has been the United States primary vehicle for carrying people and large equipment into space.
answer:
which of newtons laws of motion explains rocket propulsion?

question:
Chronic myeloid leukemia (CML) is a progressive and often fatal myeloproliferative neoplasm. The hallmark of CML is an acquired chromosomal translocation known as the Philadelphia chromosome (Ph), which results in the synthesis of the breakpoint cluster region-Abelson murine leukemia (BCR-ABL) fusion oncoprotein, a constitutively active tyrosine kinase. The introduction of imatinib, a tyrosine kinase inhibitor (TKI) that is specific for BCR-ABL, was a major breakthrough in CML therapy. Although most patients respond to first-line imatinib therapy, some experience loss of response (resistance) or require treatment discontinuation because of toxicity (intolerance). For patients with CML, failure on standard-dose imatinib therapy (400 mg daily), imatinib dose escalation (600-800 mg daily) is a second-line option. However, high-dose imatinib is not an appropriate approach for patients who experience drug toxicity, and there remain questions over the durability of responses achieved with this strategy. Alternative second-line options include the TKIs dasatinib and nilotinib. A substantial amount of long-term data for these agents is available. Although both are potent and specific BCR-ABL TKIs, dasatinib and nilotinib exhibit unique pharmacologic profiles and response patterns relative to different patient characteristics, such as disease stage and BCR-ABL mutation status. To optimize therapeutic benefit, clinicians should select treatment based on each patient's historic response, adverse-event tolerance, and risk factors.
answer:
What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

question:
As was discussed in previous concepts, both infectious and noninfectious diseases of the reproductive system can be very serious. But there are ways to keep your reproductive system healthy. What can you do to keep your reproductive system healthy? You can start by making the right choices for overall good health. To be as healthy as you can be, you should: Eat a balanced diet that is high in fiber and low in fat. Drink plenty of water. Get regular exercise. Maintain a healthy weight. Get enough sleep. Avoid using tobacco, alcohol, or other drugs. Manage stress in healthy ways. Keeping your genitals clean is also very important. A daily shower or bath is all that it takes. Females do not need to use special feminine hygiene products. In fact, using them may do more harm than good because they can irritate the vagina or other reproductive structures. You should also avoid other behaviors that can put you at risk. Do not get into contact with another persons blood or other body fluids. For example, never get a tattoo or piercing unless you are sure that the needles have not been used before. This is one of the most important ways to prevent an STI. Of course, the only way to be fully protected against STIs is to refrain from sexual activity. If you are a boy, you should always wear a protective cup when you play contact sports. Contact sports include football, boxing, and hockey. Wearing a cup will help protect the testes from injury. You should also do a monthly self-exam to check for cancer of the testes. If you are a girl and use tampons, be sure to change them every four to six hours. Leaving tampons in for too long can put you at risk of toxic shock syndrome. This is a serious condition. Signs and symptoms of toxic shock syndrome develop suddenly, and the disease can be fatal. The disease involves fever, shock, and problems with the function of several body organs. Girls should also get in the habit of doing a monthly self-exam to check for breast cancer. Although breast cancer is rare in teens, its a good idea to start doing the exam when you are young. It will help you get to know what is normal for you.
answer:
girls should perform monthly self-exams to check for