Since genomes are very complex, one research strategy is to reduce the number of genes in a genome to the bare minimum and still have the organism in question survive. There is experimental work being done on minimal genomes for single cell organisms as well as minimal genomes for multi-cellular organisms (see Developmental biology). The work is both in vivo and in silico.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What is a research strategy to understand silico?
Ah, so.. unanswerable

According to a 2001 report from The World Factbook by CIA, about 50% of Nigeria's population is Muslim, 40% are Christians and 10% adhere to local religions. But in some recent report, the Christian population is now sightly larger than the Muslim population. An 18 December 2012 report on religion and public life by the Pew Research Center stated that in 2010, 49.3 percent of Nigeria's population was Christian, 48.8 percent was Muslim, and 1.9 percent were followers of indigenous and other religions, or unaffiliated. Additionally, the 2010s census of Association of Religion Data Archives has reported that 46.5 percent of the total population is Christian, slightly bigger than the Muslim population of 45.5 percent, and that 7.7 percent are members of other religious groups.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): According to Pew, in 2010, what percent of Nigeria's population was Christian?
Ah, so.. 49.3 percent

This influx was compounded by the decline of the Western Sudanic Mali Empire in 1375 and the Songhai Empire in 1591. Additionally, as inland regions underwent desertification, inhabitants moved to the wetter coast. These new inhabitants brought skills such as cotton spinning, cloth weaving, iron smelting, rice and sorghum cultivation, and social and political institutions from the Mali and Songhai empires. Shortly after the Mane conquered the region, the Vai people of the former Mali Empire immigrated into the Grand Cape Mount region. The ethnic Kru opposed the influx of Vai, forming an alliance with the Mane to stop further influx of Vai.[citation needed]
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What happened when regions underwent desertification?
Ah, so..
inhabitants moved to the wetter coast