You will be given a definition of a task first, then some input of the task.
In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: GnRH (ganodorelin) is a hypothalamic decapeptide that is secreted in a pulsatile manner. Lately a series of analogues have been developed that:
Options: <1> All of them inhibit prolonged secretion of LH and FSH. <2> All of them are GnRH receptor agonists. <3> Goserelin and buserelin are antagonists of the GnRH receptor. <4> The prolonged treatment gives rise to a typical symptomatology of an excess of gonadal steroids. <5> GnRH agonists are contraindicated in prostate and breast cancer.
Output:
1