Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: Autosomal-recessive hereditary spastic paraplegias (AR-HSP) consist of a genetically diverse group of neurodegenerative diseases characterised by pyramidal tracts dysfunction. The causative genes for many types of AR-HSP remain elusive. We tried to identify the gene mutation for AR-HSP with cerebellar ataxia and neuropathy. This study included two patients in a Japanese family with their parents who are first cousins. Neurological examination and gene analysis were conducted in the two patients and two normal family members. We undertook genome-wide linkage analysis employing single nucleotide polymorphism arrays using the two patients' DNAs and exome sequencing using one patient's sample. We detected a homozygous missense mutation (c.4189T>G, p.F1397V) in the lysosomal trafficking regulator (LYST) gene, which is described as the causative gene for Chediak-Higashi syndrome (CHS). CHS is a rare autosomal-recessive syndrome characterised by hypopigmentation, severe immune deficiency, a bleeding tendency and progressive neurological dysfunction. This mutation was co-segregated with the disease in the family and was located at well-conserved amino acid. This LYST mutation was not found in 200 Japanese control DNAs. Microscopic observation of peripheral blood in the two patients disclosed large peroxidase-positive granules in both patients' granulocytes, although they had no symptoms of immune deficiency or bleeding tendency. We diagnosed these patients as having adult CHS presenting spastic paraplegia with cerebellar ataxia and neuropathy. The clinical spectrum of CHS is broader than previously recognised. Adult CHS must be considered in the differential diagnosis of AR-HSP.
Question: Which mutated gene causes the ChediakHigashi Syndrome?

A: lysosomal trafficking regulator gene
****
Q: Context: To develop clinical rules for the safe and effective use of flumazenil in suspected benzodiazepine overdose. We assembled a retrospective series of 35 consecutive comatose patients admitted between October 1992 and July 1993 to a toxicologic ICU with the presumptive diagnosis of drug overdose. These patients were divided into two groups. Group A (low-risk) patients had a clinical picture compatible with uncomplicated benzodiazepine intoxication (calm, without abnormalities in pulse or blood pressure, lateralizing signs, hypertonia, hyperreflexia, or myoclonus) in the absence of predefined electrocardiographic or clinical signs of tricyclic antidepressant or other proconvulsant overdose, and absence of an available history of long-term benzodiazepine treatment or an underlying seizure disorder. Group B ("non-low risk") comprised all other patients. Efficacy of flumazenil was categorized as complete awakening (with normal level of alertness), partial awakening, or no change in alertness level. The safety of flumazenil was defined on the basis of the absence of seizures or death. In group A (n=4), flumazenil was associated with complete awakening in three patients and partial awakening in one. No seizures were observed. In group B (n=31), flumazenil was associated with complete awakening in 4 patients, partial awakening in 5, and no response in 22. In group B, five seizures occurred. Comatose patients with clinical or ECG criteria thought to contraindicate the use of flumazenil have a reasonably high risk of seizures after administration of this drug. Low-risk patients may be able to receive flumazenil safely, but they may be only a small portion of comatose patients with suspected overdose.
Question: Which drug should be used as an antidote in benzodiazepine overdose?

A: flumazenil
****
Q: Context: Between 1911 and 1912, over 1,000 Somalis from Mogadishu, the then capital of Italian Somaliland, served as combat units along with Eritrean and Italian soldiers in the Italo-Turkish War. Most of the troops stationed never returned home until they were transferred back to Italian Somaliland in preparation for the invasion of Ethiopia in 1935. The first disembarkation of Italian troops occurred on October 10. The Italian contingent of 20,000 troops was deemed sufficient to accomplish the conquest at the time. Tobruk, Derna and Khoms were easily conquered, but the same was not true for Benghazi. The first true setback for the Italian troops happened on October 23, when poor placement of the troops near Tripoli led them to be almost completely encircled by more mobile Arab cavalry, backed by some Turkish regular units. The attack was portrayed as a simple revolt by the Italian press, but it nearly annihilated much of the small Italian expeditionary corps. The corps was consequently enlarged to 100,000 men who had to face 20,000 Arabs and 8,000 Turks. The war turned into one of position. Even some of the earliest examples of utilisation in modern warfare of armoured cars and air power by the Italian forces had little effect on the initial outcome. However, the war was notable for the first military use of heavier-than-air craft. Capitano Carlo Piazza flew the first military reconnaissance flight on 23 October 1911. A week later, Sottotenente Giulio Gavotti dropped four grenades on Taguira and Ain Zara in history's first aerial bombing.
Question: What happened first: first disembarkation of Italian troops or their encircling by Arab cavalry?

A:
first disembarkation of italian troops
****