Detailed Instructions: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
Problem:Paragraph: Hepadnaviruses infect several animal species. The prototype species, human hepatitis B virus (HBV), increases the risk of liver diseases and may cause cirrhosis and hepatocellular carcinoma. Recently a novel hepadnavirus, similar to HBV, has been identified through transcriptomics studies in a domestic cat with large cell lymphoma in Australia. Herewith, a collection of 390 feline serum samples was screened for hepadnavirus. Overall, the virus was identified in 10.8% of the sera with a significantly higher prevalence (17.8%) in the sera of animals with a clinical suspect of infectious disease. Upon genome sequencing, the virus was closely related (97.0% nt identity) to the prototype Australian feline virus Sydney 2016. The mean and median values of hepadnavirus in the feline sera were 1.3 10 6 and 2.1 10 4 genome copies per mL (range 3.3 10 0 -2.5 10 7 genome copies per mL). For a subset of hepadnavirus-positive samples, information on the hemato-chemical parameters was available and in 10/20 animals a profile suggestive of liver damage was present. Also, in 7/10 animals with suspected hepatic disease, virus load was >10 4 genome copies per mL, i.e. above the threshold considered at risk of active hepatitis and liver damage for HBV. Viruses of the genus Orthohepadnavirus, family Hepadnaviridae, are partially double-stranded DNA viruses that infect a variety of mammals. Chronic infections in humans of the prototype species, hepatitis B virus (HBV), increase the risk of liver diseases including cirrhosis and hepatocellular carcinoma 1 . Hepadnaviruses have been identified in several animal species including primates, bats, rodents, birds and fish 2 . Recently a novel member of the family Hepadnaviridae, similar to HBV, has been identified through transcriptomics studies in a domestic cat with large cell lymphoma 3 . Preliminary epidemiological data collected by Australian researchers suggest that the hepadnavirus of domestic cat (DCH) is common in cats infected with feline immunodeficiency virus (FIV) 3 . In order to gather additional information on DCH, we analyzed sera collected from household cats with different age (0-15 years) and clinical histories, obtained from veterinary diagnostic laboratories.
Title: Identification of hepadnavirus in the sera of cats OPEN
Solution:
True