Given the task definition and input, reply with output. Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Paragraph: This story informs the reader of the cost range for some generic and brand name drugs. It states that a 3-month supply of alendronate, a genericversion of Fosamax, costs about $100and that biannual infusions of the Novartis drug Zometa costs up to $1,200. Although it is not stated, theseare estimated retail costs. This story does a good job of presenting potential benefits in detail, including the number of women in each study, the study design and factors that need to be taken into account when considering the results. Results are presented in both relative and absolute terms. For example,one of the studiesreported about a30% decreased incidence of developing invasive breast cancer overabout 8 years in women who took oral bisphosphonates compared to those who did not. The story explains that in absolute terms, for every 1,000 women taking bisphosphonates for one year there would be one less case of invasive breast cancer. The story mentions some of thepotentially severeside effects of bisphosphonates including bone, joint or muscle pain and, in rare cases, jawbone decay. The story also mentioned that one of the studies showed a slight increased risk of noninvasive tumors in women who took bisphosphonatescompared to those whodid not. It could have also mentioned that gastrointestinal distress is another potential side effect, but did confirm that bisphosphonates are generally well-tolerated. The story should have emphasized that this was an observational study and that the association is just that an association, not cause and effect. Women who develop osteoporosis tend to be women who may have lower breast cancer risk to begin with, perhaps due to lower circulating estrogen levels. This concern was addressed in a New York Times story the same studies: Claim: Studies: Bone drugs may help prevent breast cancer
This story covers the results of preliminary findings of two large observational studies presented at the San Antonio Breast Cancer Symposium which suggest that bisphosphonates, for example Fosamax,Boniva and Actonel,may play a role in reducing the risk of breast cancer. This story was informative and provideda high level of detail abouthow the studies were designed. Itpresented resultsin both relative and absolute terms. The story described the significance of the researchbut clearly indicated that roleofbisphosphonates in breast cancer prevention is anunfolding story that requires further investigation. Breast cancer is the second leading cause of cancer-related death in women, following lung cancer. Currently, there are no preventive measures for women of average risk. The research results reported in this story add to other recent studies that have createdinterest inthe potential roles of bisphosphonates which are taken by millions of women with bone loss andosteoporosis in reducing cancer risk.