Given an abstract of a paper, generate a title for this paper such that conveys the key focus of the paper.
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Question: Abstract: Distribution and elimination of cefamandole 2 g iv were studied in 11 morbidly obese patients during a gastric bypass operation and again on the first postoperative day. Serum, subcutaneous adipose tissue, wound drainage, and urine were analyzed by high performance liquid chromatography for cefamandole and pharmacokinetic parameters from the intraoperative period were compared to those obtained postoperatively. Total body clearance was significantly greater (p less than 0.001) postoperatively (297 ml/min) than intraoperatively (254 ml/min). Volume changes were unpredictable but the elimination rate constant tended to increase postoperatively. Renal clearance and percentage of urinary recovery were significantly increased (p less than 0.01) postoperatively. The patients had a mean (+/- SD) volume of the central compartment of 10.3 (+/- 2.3) L, volume at steady state of 18.3 (+/- 3.9) L, and elimination rate constant of 1.67 (+/- 0.63) h-1. Tissue concentrations of cefamandole were highest during the first hour after drug administration and were less than 1 microgram/g after 3.5 hours. Mean wound drainage concentrations ranged between 10 and 12 micrograms/ml during a dosing interval and dropped to 7 micrograms/ml 12 hours after the last dose. Intraoperative dosing of cefamandole is required to maintain subcutaneous adipose tissue concentrations greater than 1 microgram/g during procedures longer than three hours in morbidly obese patients. A postoperative dose of cefamandole 2 g iv q6h will provide sustained and therapeutic concentrations in the wound drainage of morbidly obese patients.

Answer: Cefamandole distribution in serum, adipose tissue, and wound drainage in morbidly obese patients.

Question: Abstract: A series of 105 operative cases of thoracic and lumbar spine trauma is presented. All patients underwent an anterior decompression and fusion via the lateral extracavity approach with or without an accompanying posterior internal stabilization procedure (modified Weiss springs or Harrington distraction rods). All patients were allowed to plateau neurologically before reconstructive spine surgery was performed. The patient's neurological grade at the time of surgery and after recovery was assessed according to a seven-grade scale presented herein. None of the 34 patients with a motor and sensory complete myelopathy recovered any function below the level in injury. Of the 10 motor-complete patients with some sensory perception, 4 improved neurologically; however, only 1 of these improved to a state of limited ambulation. The rest remained nonambulatory. Of the 33 patients with significantly disabling incomplete motor and sensory myelopathies, 17 improved to a level of minimal neurological deficit; only 3 patients were left nonambulatory. Of the 21 patients whose physical finding demonstrated a minimal neurological deficit preoperatively, 17 recovered to a normal neurological state. Seven patients were neurologically normal preoperatively and were unchanged postoperatively. Reconstruction of the spine with an anterior decompression and an accompanying stabilization procedure, when appropriate, leads to a better neurological outcome than that expected with either a conservative, nonoperative approach or an operative posterior stabilization approach.

Answer: Functional recovery after decompressive operation for thoracic and lumbar spine fractures.

Question: Abstract: Competency tests were developed for Oklahoma's Dietetic Support Personnel Training Program to assure the professional quality of its graduates. The tests' content validity was assured through an elaborate committee validation process. The tests' reliability was investigated using split-halves methods, and their criterion-related validity was investigated using non-parametric methods to correlate workers' test scores with employers' on-the-job performance ratings. The tests' reliability indexes varied between 0.88 and 0.97, indicating their consistency. Their validity indexes varied between 0.13 and 0.78, indicating the need for further work in some test areas.

Answer:
Developing competency tests for Oklahoma's dietetic support personnel program.