Premise:
"An estimated four billion copies of her novels have been sold."
Hypothesis: Her novels sell very well to middle-aged women.

it is not possible to tell

Premise:
"T-ACE addresses problems over the patient's lifetime and takes 1 to 2 minutes to administer."
Hypothesis: T-ACE has historically been able to detect multiple types of rare cancers before other tests.

it is not possible to tell

Premise:
"Problems identified in the design review process can become a powerful tool to improve performance."
Hypothesis: Identifying issues can help the review process.
yes