Two university students studied different types of drugs for their exams. Kate studied statins, while Carol studied anti-depressants. Which student learned more about inducing the expression of low density lipoprotein (LDL) receptors in the liver? Hint: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem.
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Answer: Kate

This year scientist found concrete evidence of existence of black holes by taking photograph of one. Unfortunately, the originator of black hole theory, Stephen Hawking, was never awarded a Nobel prize despite letting science advance in big leap because his theory could not be verified during his lifetime. On the other hand, scientist B has received Nobel prize because he has based his theory on the earlier theory of scientist A. Would scientist A increased our understanding of the world more or less than scientist B? Hint: The above example shows how science generally advances. New evidence is usually used to improve earlier ideas rather than entirely replace them. In this way, scientists gradually refine their ideas and increase our understanding of the world. On the other hand, sometimes science advances in big leaps. This has happened when a scientist came up with a completely new way of looking at things. For example, Albert Einstein came up with a new view of gravity. He said it was really just a dent in the fabric of space and time.
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Answer: less

Dan found three rattle snakes: one only had one rattle, the second snake had 4 rattles and the third snake had seven rattles on its tail. Which snake was older, the first or the third snake Dan found? Hint: At birth, a rattlesnake hatchling has only a small button or 'primordial rattle' which is firmly attached to the tip of the tail.[13] The first segment is added when the hatchling sheds its skin for the first time.[14] A new section is added each time the skin is shed until a rattle is formed. The rattle grows as the snake ages but segments are also prone to breaking off and hence the length of a rattle is not a reliable indicator of the age of a snake.[15]
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Answer:
the third