Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder resulting in the growth of a variety of tumours, and is inherited in an autosomal dominant pattern. Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours that commonly harbour oncogenic mutations in KIT or PDGFRA and are thought to arise from the interstitial cells of Cajal (ICC; the pacemaker cells of the gut). To characterise two patients with NF1 and GISTs. Two patients were genotyped for germline mutations in NF1. GISTs from both patients were genotyped for somatic mutations in KIT and PDGFRA. Loss of heterozygosity (LOH) of NF1 in one GIST was assessed by genotyping seven microsatellite markers spanning 2.39 Mb of the NF1 locus in the tumour and in genomic DNA. The known germline mutation in NF1 was confirmed in GIST DNA by sequencing. The copy number of the mutated NF1 allele was determined by multiplex ligand-dependent probe amplification. GISTs from both patients were of wild type for mutations in KIT and PDGFRA. In the GIST with adequate DNA, all seven markers were informative and showed LOH at the NF1 locus; sequencing of NF1 from that GIST showed no wild-type sequence, suggesting that it was lost in the tumour. Multiplex ligand-dependent probe amplification analysis showed that two copies of all NF1 exons were present. This is the first evidence of mitotic recombination resulting in a reduction to homozygosity of a germline NF1 mutation in an NF1-associated GIST. We hypothesise that the LOH of NF1 and lack of KIT and PDGFRA mutations are evidence of an alternative pathogenesis in NF1-associated GISTs.

Output: Which is the gene mutated in type 1 neurofibromatosis?

Input: Consider Input: The Gora Rudnaya mine is one of the largest gold mines in Russia and in the world.

Output: What product does Gora Rudnaya mine make?

Input: Consider Input: Singles' Day, also called Double Eleven, began as a day for unmarried or uncoupled people to celebrate their lives on November 11, 1993. In China, however, Singles' Day has become the biggest online shopping day in the world, which was created in 2009 by Alibaba's CEO Daniel Zhang to increase online sales. Since then, it has grown into a cultural phenomenon. China Singles' Day, as a shopping day, takes place on November 11 each year. There are sharp _ and other promotions designed by Alibaba to attract online customers. In 2015, E-commerce giant Alibaba broke records with sales of $14.3 billion on China Singles' Day, with online sales increasing 60 percent from last year, according to Alibaba. "Most people shop on mobile phones or ipads and online shopping has become a comfortable channel for most consumers", said Kitty Fok, China manager for market research. "China is a big market with close to one billion smart, connected device users. It is good news for both Alibaba and their competitors," she said. The company is focusing on international e-commerce for future Singles' Days, reported Reuters. "Within the next five years, we expect China will become the world's largest e-commerce market for imported products," President Michael Evans told reporters on Wednesday. Alibaba Chief Executive Daniel Zhang said in a statement that Singles' Day would mean that "the whole world will see the power of Chinese consumption." Over 130 million users visited Alibaba's marketplace app, Taobao, reported the BBC.
Output: What does Alibaba expect to do on Singles' Day?