In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Input: Consider Input: Purpose: To provide recommendations and standard operating procedures (SOPs) for intensive care unit (ICU) and hospital preparations for an influenza pandemic or mass disaster with a specific focus on protection of patients and staff. Methods: Based on a literature review and expert opinion, a Delphi process was used to define the essential topics including protection of patients and staff. Results: Key recommendations include: (1) prepare infection control and occupational health policies for clinical risks relating to potential disease transmission; (2) decrease clinical risks and provide adequate facilities through advanced planning to maximise capacity by increasing essential equipment, drugs, supplies and encouraging staff availability; (3) create robust systems to maintain staff confidence and safety by minimising non-clinical risks and maintaining or escalating essential services; (4) prepare formal reassurance plans for legal protection; (5) provide assistance to staff working outside their normal domains. Conclusions: Judicious planning and adoption of protocols for protection of patients and staff are necessary to optimise outcomes during a pandemic.

Output: Chapter 6. Protection of patients and staff during a pandemic

Input: Consider Input: The novel coronavirus, COVID-19, has sparked an outflow of scientific research seeking to understand the virus, its spread, and best practices in prevention and treatment. If this international research effort is going to be as swift and effective as possible, it will need to rely on a principle of open science. When researchers share data, code, and software and generally make their work as transparent as possible, it allows other researchers to verify and expand upon their work. Furthermore, it allows public officials to make informed decisions. In this study, we analyzed 535 preprint articles related to COVID-19 for eight transparency criteria and recorded study location and funding information. We found that individual researchers have lined up to help during this crisis, quickly tackling important public health questions, often without funding or support from outside organizations. However, most authors could improve their data sharing and scientific reporting practices. The contrast between researchers' commitment to doing important research and their reporting practices reveals underlying weaknesses in the research community's reporting habits, but not necessarily their science.

Output: Reproducibility and reporting practices in COVID-19 preprint manuscripts

Input: Consider Input: Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines. Viruses 2019, 11, 74 2 of 17 Preclinical vaccine development for both SARS-CoV and MERS-CoV has largely aimed to stimulate a robust immune response against the viral envelope-protruding spike (S) glycoprotein [28, 29] , a class I fusion protein, and/or the nucleocapsid (N) protein [30, 31] . MERS-CoV S is proteolytically cleaved by host furin [32] during maturation into an S1 domain responsible for binding to DPP4 as well as an S2 domain containing two heptad-repeat regions that facilitate membrane fusion (Figure 1 ). The S1 domain can be further divided into the N-terminal domain (NTD), or S1 A , associated with binding sialic acid [33] , and the receptor binding domain (RBD), comprising the majority of the C-terminal domain of S1. Cryo-electron microscopy studies have shown that the RBD is flexible and opens upward or away from the viral envelope in order to establish contact with DPP4, which may expose S2' [34], a second protease cleavage site within S2. Cleavage at S2' is necessary for membrane fusion upon viral entry [32] . The centrality of S to viral entry helps explain why antibodies that target it are potently neutralizing [35] . On the other hand, while CoV N proteins are abundantly expressed during infection [36] , immunization with SARS-CoV N did not induce strongly neutralizing antibodies [37], likely because N is not displayed on the viral surface. However, N is more conserved than S within CoV lineage [38] , and vaccination with SARS-CoV N was shown to induce cytotoxic T cell responses in mice [39] . Therefore, N may help induce cell-mediated immunity to CoV infection [40] , as may S [41]. CD4+ and CD8+ T cell responses from recovered MERS-CoV patients were particularly strong towards N peptides [42] . However, vaccination with N-based immunogens may carry risks associated with T h 2-related eosinophilic immune enhancement [43] , as may S-based vaccines [44] . Notwithstanding, because of the protection afforded by the robust immune response it generates, S has been the target of most vaccine candidates for MERS-CoV. In this review, we summarize the current state of MERS-CoV vaccine candidates and also describe potential barriers to MERS-CoV vaccine efficacy that first surfaced during research on developing a SARS-CoV vaccine.
Output: viruses Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism