QUES: The stagnation and decline, Stephen Lee argues, was relentless after the death of Suleiman in 1566, interrupted by a few short revivals or reform and recovery. The decline gathered speed so that the Empire in 1699 was, "a mere shadow of that which intimidated East and West alike in 1566." Although there are dissenting scholars, most historians point to "degenerate Sultans, incompetent Grand Viziers, debilitated and ill-equipped armies, corrupt officials, avaricious speculators, grasping enemies, and treacherous friends." The main cause was a failure of leadership, as Lee argues the first 10 sultans from 1292 to 1566, with one exception, had performed admirably. The next 13 sultans from 1566 to 1703, with two exceptions, were lackadaisical or incompetent rulers, says Lee. In a highly centralized system, the failure at the center proved fatal. A direct result was the strengthening of provincial elites who increasingly ignored Constantinople. Secondly the military strength of European enemies grew stronger and stronger, while the Ottoman armies and arms scarcely improved. Finally the Ottoman economic system grew distorted and impoverished, as war caused inflation, world trade moved in other directions, and the deterioration of law and order made economic progress difficult.
Beginning and ending with what years does Lee argue that the rules of the Empire were incompetent?

ANS: 1566 to 1703

QUES: The firm continued to pressure Kelsey and the agency to approve the applicationuntil November 1961, when the drug was pulled off the German market because of its association with grave congenital abnormalities. Several thousand newborns in Europe and elsewhere suffered the teratogenic effects of thalidomide. Though the drug was never approved in the USA, the firm distributed Kevadon to over 1,000 physicians there under the guise of investigational use. Over 20,000 Americans received thalidomide in this "study," including 624 pregnant patients, and about 17 known newborns suffered the effects of the drug.[citation needed]
Why was this drug pulled off shelves?

ANS: association with grave congenital abnormalities

QUES: If Mammalia is considered as the crown group, its origin can be roughly dated as the first known appearance of animals more closely related to some extant mammals than to others. Ambondro is more closely related to monotremes than to therian mammals while Amphilestes and Amphitherium are more closely related to the therians; as fossils of all three genera are dated about 167 million years ago in the Middle Jurassic, this is a reasonable estimate for the appearance of the crown group. The earliest known synapsid satisfying Kemp's definitions is Tikitherium, dated 225 Ma, so the appearance of mammals in this broader sense can be given this Late Triassic date. In any case, the temporal range of the group extends to the present day.
Which group are Ambondro's closely related to?

ANS: monotremes

QUES: Steven Waldman notes that; "The evangelicals provided the political muscle for the efforts of Madison and Jefferson, not merely because they wanted to block official churches but because they wanted to keep the spiritual and secular worlds apart." "Religious freedom resulted from an alliance of unlikely partners," writes the historian Frank Lambert in his book The Founding Fathers and the Place of Religion in America. "New Light evangelicals such as Isaac Bachus and John Leland joined forces with Deists and skeptics such as James Madison and Thomas Jefferson to fight for a complete separation of church and state."
What profession doesn't Frank Lambert have?

ANS:
unanswerable