A same meaning or not problem:
However , the artificial side-effect profile of overall tears is very low .
The entire side-effect profile of artificial tears is , however , very low .
****
[A]: no

A same meaning or not problem:
Cowie began producing music after he stopped buying drugs as an alternative to making money .
Cowie began producing music after he stopped dealing drugs as an alternative to making money .
****
[A]: yes

A same meaning or not problem:
In 1975 , the then Alan Rees Eleri Morgan was married .
In 1975 , the then Alan Rees married Eleri Morgan .
****
[A]: yes

A same meaning or not problem:
Dragon Wars is a fantasy role-playing videogame developed by Rebecca Heineman , published in 1989 by Interplay Productions and distributed by Activision .
Dragon Dragon Wars is a fantasy role-playing videogame developed by Rebecca Heineman and published in 1989 by Activision and distributed by Interplay Productions .
****
[A]:
no