You will be given a definition of a task first, then some input of the task.
In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Urine is hypoosmolar with respect to plasma in:
Options: <1> Bowman's capsule. <2> Proximal tubule <3> Medulla area of the loop of Henle. <4> Initial zone of the distal tubule. <5> Collecting tubule in the presence of ADH.
Output:
4