TASK DEFINITION: In this task, you are given a passage which has a question and the context. You have to generate an answer to the question based on the information present in the context.
PROBLEM: Context: To introduce an elastomeric continuous infusion pump for pain control after outpatient orbital implant surgery.', 'Retrospective, noncomparative consecutive case series of all patients undergoing enucleation, evisceration, or secondary orbital implantation using the On-Q pain system between August 2004 and January 2006. Postoperative pain score, need for narcotics, and adverse events were recorded. The On-Q catheter is inserted intraoperatively through the lateral lower eyelid into the muscle cone under direct visualization, prior to the orbital implant placement. The On-Q system continually infuses anesthesia (bupivacaine) to the retrobulbar site for 5 days.', 'Among 20 patients, mean postoperative period pain score, with On-Q in place, was 1.3 (scale of 0 to 10). Nine patients (45%) did not need any adjunctive oral narcotics. Two patients experienced postoperative nausea. One catheter connector leaked, thereby decreasing delivery of retrobulbar anesthetic resulting a pain level of 6, the highest level in the study. There were no postoperative infections. No systemic toxic effects from bupivacaine were observed clinically.\Question: Do on-Q pump for pain control after orbital implant surgery?

SOLUTION: The On-Q pain pump is widely available, low cost, and requires minimal patient manipulation for the use in orbital implant surgery. The device was safe and appeared to minimize postoperative pain in the authors' case series.

PROBLEM: Context: Sleep disorders are associated with cardiovascular complications and preterm delivery (PTD). Insufficient sleep results in metabolic alterations and increased inflammation, both known to contribute to placental abruption (abruption), a determinant of PTD. We examined associations of abruption with sleep duration and complaints of vital exhaustion.', 'The study included 164 abruption cases and 160 controls in a multicenter study in Peru. Data on habitual sleep duration and vital exhaustion during the first 6 months of pregnancy were elicited during interviews conducted following delivery. Women were categorized according to short, normal and long sleep duration (6, 7-8 and 9h); and frequency of feeling exhausted. Odds ratios (OR) and 95% confidence intervals (CI) were calculated.', 'Short and long sleep durations were associated with increased odds of abruption. The ORs of abruption in relation to short (6h) and long (9h) sleep duration were 2.0 (95% CI 1.1-3.7) and 2.1 (95% CI 1.1-4.1), compared with normal sleep duration (7-8h). Complaints of vital exhaustion were also associated with abruption (OR=2.37; 95% CI 1.46-3.85), and were independent of sleep duration.\Question: Is maternal sleep duration and complaints of vital exhaustion during pregnancy associated with placental abruption?

SOLUTION: We extend the existing literature and support the thesis that maternal sleep habits and disorders should be assessed among pregnant women.

PROBLEM: Context: Although elevated serum IgE levels have been reported in psoriasis, the role of IgE in psoriasis still needs to be clarified.', 'To analyse serum total IgE levels in addition to the presence and distribution of IgE and FcRI in psoriatic lesions, and to investigate alteration of IgE and FcRI after successful systemic treatment.', 'Total serum IgE levels were determined using enzyme-linked immunosorbent assay. The expression and localization of IgE and FcRI was investigated using immunohistochemistry and double immunofluorescence.', 'Elevated total serum IgE levels were found in 39% of patients with psoriasis. The levels of total serum IgE were significantly higher in male patients compared with female patients. Furthermore, total serum IgE levels decreased after successful systemic treatment. A positive correlation between IgE+ and FcRI+ cells and a significant increase of these cells was found in psoriatic lesions when compared with normal skin. Interestingly, IgE+ and FcRI+ cells decreased significantly after successful therapy with ustekinumab. IgE and FcRI were coexpressed on mast cells, epidermal Langerhans cells, dermal dendritic cells, macrophages and a small number of neutrophils.\Question: Are igE and FcRI highly expressed on innate cells in psoriasis?

SOLUTION:
IgE might participate in the development of psoriasis by activating FcRI-bearing cells.