input: Please answer the following: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. Ben and Andy were two old friends. They both have high levels of cholesterol. Ben was prescribed cholesterol medication, while Andy didn't go to the doctor because he was careless. Which friend took a drug that induces the expression of low density lipoprotein (LDL) receptors in the liver?
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output: Ben

Please answer this: The Figure below shows decibel levels of several different sounds. As decibel levels get higher, sound waves have greater intensity and sounds are louder. For every 10-decibel increase in the intensity of sound, loudness is 10 times greater. Therefore, a 30-decibel "quiet" room is 10 times louder than a 20-decibel whisper, and a 40-decibel light rainfall is 100 times louder than the whisper. High-decibel sounds are dangerous. They can damage the ears and cause loss of hearing. James is attending a concert. When he first walks in the concert hall there aren't that many people there and it is relatively quiet. As the room fills up it starts to get a bit louder. And when the concert starts its so loud that it is almost painful for him as he is sitting near the speakers. Given that during the concert the decibel levels were high enough to be painful to James, will further increasing them make them safer or harmful?
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Answer: harmful

Problem: Antifreeze could also be called "antiboil" because it also raises the boiling point of the water in a car radiator. Hot weather combined with a hot engine can easily raise the temperature of the water in the radiator above 100 C, which is the boiling point of pure water. If the water boils, it could cause the engine to overheat and become seriously damaged. However, if antifreeze has been added to the water, the boiling point is much higher. For example a 50 percent antifreeze solution has a boiling point of 129 C. Unless the water gets hotter than this, it won't boil and ruin the engine. John was driving through the Mohave desert. He first added antifreeze to the water in his radiator. He noted that in his journal as case A. Unfortunately, after some time he ran out of antifreeze, and couldn't add antifreeze any more. He noted that as case B. In case A would the engine be hotter or cooler than in case B?

A: cooler

Problem: Given the question: As for the public health or food safety concern, organic foods are intended to be healthy, free of contaminations and free from agents that could cause human diseases. Organic milk is meant to have no chemical residues to consumers, and the restrictions on the use of antibiotics and chemicals in organic food production has the purpose to accomplish this goal. Although dairy cows in both organic and conventional farming practices can be exposed to pathogens, it has been shown that, because antibiotics are not permitted as a preventative measure in organic practices, there are far fewer antibiotic resistant pathogens on organic farms. This dramatically increases the efficacy of antibiotics when/if they are necessary. Manny and Annie were two foodie friends. Manny was a health conscious person, he ate organic foods and drank organic milk only. Annie liked all foods, whether they were organic or not. Which friend drank less milk from cows exposed to fewer antibiotic resistant pathogens?
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The answer is:
Annie

input question: The major zones in river ecosystems are determined by the river bed's gradient or by the velocity of the current. Faster moving turbulent water typically contains greater concentrations of dissolved oxygen, which supports greater biodiversity than the slow moving water of pools. These distinctions form the basis for the division of rivers into upland and lowland rivers. The food base of streams within riparian forests is mostly derived from the trees, but wider streams and those that lack a canopy derive the majority of their food base from algae. Anadromous fish are also an important source of nutrients. Environmental threats to rivers include loss of water, dams, chemical pollution and introduced species. A dam produces negative effects that continue down the watershed. The most important negative effects are the reduction of spring flooding, which damages wetlands, and the retention of sediment, which leads to loss of deltaic wetlands. Two rivers spring from the same mountain. Olt was a fast moving river, while Mures river was slow moving and deep. Both rivers are very important for the local economies. Which river had a water that supports greater biodiversity????
output answer: Olt

input question: Common foodborne viruses include norovirus and hepatitis A virus. Norovirus, which causes inflammation of the stomach and intestines, has been a recent issue on cruise ships, infecting hundreds of passengers and crew on certain voyages. Hepatitis A causes inflammation of the liver, which is treated with rest and diet changes. Parasites are tiny organisms that live inside another organism. Giardia is a parasite spread through water contaminated with the stools of people or animals who are infected. Food preparers who are infected with parasites can also contaminate food if they do not thoroughly wash their hands after using the bathroom and before handling food. Trichinella is a type of roundworm parasite. People may be infected with this parasite by consuming raw or undercooked pork or wild game. Two brothers had very bad luck when they attended a wedding. Tom fell violently ill after eating some tainted food, and he was rushed to the hospital. His brother Rob felt sick later, after eating the main course. Tom was infected with norovirus and hepatitis A, while Rob was infected with Giardia and Trichinella. Which brother experienced less inflammation of the stomach????
output answer:
Rob