You will be given a definition of a task first, then some input of the task.
Given a passage, construct a question on the basis of the information present in the passage. Construct the question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) it answer uses text phrases from the passage. Avoid creating questions that (i) can't be answered correctly without actually understanding the passage and (ii) uses the same words or phrases given in the passage.

To evaluate the association of HLA-B51 and ocular involvement in Adamantiades-Behcet's disease.", "We retrospectively analysed all patients with Adamantiades-Behcet's disease examined in our Department of Ophthalmology since 1982. All patients fulfilled the criteria of the International Study Group for Behcet's disease. We included 140 patients (63 female and 77 male) with a mean follow-up of 6.4 years.", 'The mean age at the first manifestation was 23 years; full disease was noted at 32 years. The mean age at the time of eye involvement was 30 years. Most of the patients were of Turkish (n=73) or German (n=34) origin. A total of 56% patients developed eye involvement. Forty-nine out of 76 HLA-B51-positive patients (64.5%) and 26 out of 60 HLA-B51-negative patients (43.3%; P=0.014) developed ocular involvement.
Output:
Is ocular involvement associated with HLA-B51 in Adamantiades-Behcet 's disease?