Background: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. Paragraph: Brad and Henry were two old friends in their 70's. Brad had very high levels of cholesterol, while Henry was healthier and had normal levels of cholesterol. Given the paragraph above, please answer correctly the following question: Which friend does not take a drug that removes cholesterol from plasma?
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Answer: Henry

Background: Light may transfer its energy to matter rather than being reflected or transmitted by matter. This is called absorption . When light is absorbed, the added energy increases the temperature of matter. If you get into a car that has been sitting in the sun all day, the seats and other parts of the car's interior may be almost too hot to touch, especially if they are black or very dark in color. That's because dark colors absorb most of the sunlight that strikes them. Paragraph: Marcus is going for a walk outside. He is wearing a black shirt and notices it feels very hot to him. His friend Adam joins him shortly after. Adam is wearing a white shirt and expressed to Adam how nice it is outside. He doesn't feel nearly as hot as Marcus. Given the paragraph above, please answer correctly the following question: Will a car painted white absorb more or less energy from light than a black painted car?
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Answer: less

Background: When waves travel into areas of shallow water, they begin to be affected by the ocean bottom. The free orbital motion of the water is disrupted, and water particles in orbital motion no longer return to their original position. As the water becomes shallower, the swell becomes higher and steeper, ultimately assuming the familiar sharp-crested wave shape. After the wave breaks, it becomes a wave of translation and erosion of the ocean bottom intensifies. Paragraph: John studies erosion of soil due to ocean wave. To facilitate his study he measured wave in three different points, point A, point B, and point C. Point A is in deep water. Point B is in shallow water, and point C is in even shallower water. He needs to publish his findings after analyzing the data. Given the paragraph above, please answer correctly the following question: Would point B have higher or lower swell than point C?
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Answer:
lower