input: Make use of the article to answer the questions. CHAPTER VI. A CONTINUATION OF THE REMINISCENCES OF JOHN WATSON, M.D.

OUR prisoner's furious resistance did not apparently indicate any ferocity in his disposition towards ourselves, for on finding himself powerless, he smiled in an affable manner, and expressed his hopes that he had not hurt any of us in the scuffle. "I guess you're going to take me to the police-station," he remarked to Sherlock Holmes. "My cab's at the door. If you'll loose my legs I'll walk down to it. I'm not so light to lift as I used to be."

Gregson and Lestrade exchanged glances as if they thought this proposition rather a bold one; but Holmes at once took the prisoner at his word, and loosened the towel which we had bound round his ancles. [23] He rose and stretched his legs, as though to assure himself that they were free once more. I remember that I thought to myself, as I eyed him, that I had seldom seen a more powerfully built man; and his dark sunburned face bore an expression of determination and energy which was as formidable as his personal strength.

"If there's a vacant place for a chief of the police, I reckon you are the man for it," he said, gazing with undisguised admiration at my fellow-lodger. "The way you kept on my trail was a caution."

"You had better come with me," said Holmes to the two detectives.

"I can drive you," said Lestrade.

"Good! and Gregson can come inside with me. You too, Doctor, you have taken an interest in the case and may as well stick to us." 1. Had the prisoner resisted arrest?
2. Did this mean he hated the people arresting him?
3. Where are they going to take him
4. What is holding his feet together?
5. Did they take it loose?
6. Why?
7. Where?
8. Who does he ask to untie him?
9. Is he a big guy?
10. Who doesn't really trust him?
11. How does?
12. Is something wrong with his face?
13. What?
14. What job did he suggest someone apply for?
15. What did the guy do to make him think that?
16. Who's gong to drive?
17. Who is invited to come along?
numbered_answers: 1. yes
2. no
3. the police-station
4. a towel
5. yes
6. so he could walk
7. to his cab
8. Sherlock Holmes
9. yes
10. Gregson and Lestrade
11. Holmes
12. yes
13. sunburned
14. chief of the police
15. kept on his trail
16. Lestrade
17. Doctor

input: Make use of the article to answer the questions. UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.

The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services. SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases. PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Georgetown University Medical Center in Washington, DC, USA, is heir to the oldest protein sequence database, Margaret Dayhoff's Atlas of Protein Sequence and Structure, first published in 1965. In 2002, EBI, SIB, and PIR joined forces as the UniProt consortium.

Each consortium member is heavily involved in protein database maintenance and annotation. Until recently, EBI and SIB together produced the Swiss-Prot and TrEMBL databases, while PIR produced the Protein Sequence Database (PIR-PSD). These databases coexisted with differing protein sequence coverage and annotation priorities.

Swiss-Prot was created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and subsequently developed by Rolf Apweiler at the European Bioinformatics Institute. Swiss-Prot aimed to provide reliable protein sequences associated with a high level of annotation (such as the description of the function of a protein, its domain structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recognizing that sequence data were being generated at a pace exceeding Swiss-Prot's ability to keep up, TrEMBL (Translated EMBL Nucleotide Sequence Data Library) was created to provide automated annotations for those proteins not in Swiss-Prot. Meanwhile, PIR maintained the PIR-PSD and related databases, including iProClass, a database of protein sequences and curated families. 1. When was Swiss-Prot developed?
2. By whom?
3. Was he working on a dissertation at the time?
4. Was he working on his PhD?
5. Which entity helped Amos in the development?
6. Did someone later work on its development?
7. Who?
8. And his entity?
9. What is the use of UniProt?
10. What is the NBRF?
11. From which institution?
numbered_answers: 1. 1986
2. Amos Bairoch
3. unknown
4. Yes
5. Swiss Institute of Bioinformatics
6. Yes
7. Rolf Apweiler
8. European Bioinformatics Institute
9. database of protein sequence and functional information
10. National Biomedical Research Foundation
11. Georgetown University Medical Center

input: Make use of the article to answer the questions. Mary David knew she wanted to be a movie star when she was very young. She was not sure what gave her the idea, but she wanted to look like a movie star. "I have a lot of pictures from my childhood of me wearing sunglasses," she says. "I used to wear them to watch TV." Early movie actors started wearing sunglasses, not because they looked good, but because their eyes hurt. The lights used on movie sets were really bright and could cause a painful problem known as "Klieg eyes". It was named after the Klieg brothers who invented the lights. Actors wore sunglasses to give their eyes a rest. But when movie stars began wearing their sunglasses in public, they quickly became a must. From then on, actors started wearing sunglasses in their movies as well as on the street. Audrey Hepburn wore ultra-cool Ray-Ban sunglasses in the 1961 movie, Breakfast at Tiffany's. As a result, Ray-Ban sunglasses started to appear more and more in the movies. In 1979, Ray-Ban "Wayfarers" were worn by Jake and Elwood in The Blue Brothers. Tom Cruise wore Ray-Ban "Aviator" sunglasses in the 1986 hit, Top Gun. Then in 1997, Will Smith and Tommy Lee Jones made Ray-Ban "Predator" sunglasses famous in Men in Black. 1. why did early movie actors wear sunglasses?
2. what did mary david want to be?
3. what did she like to wear when she was young?
4. what was the name of the painful problem that lights can cause?
5. named after who?
6. what year did the movie breakfast at tiffany's come out?
7. who was in it?
8. what brand of glasses did she wear?
9. who wore Wayfarers?
10. in what movie?
11. from what year?
12. Did Tom Cruise also wear Ray-Ban?
13. what style?
14. in what movie?
15. what year did that come out?
16. did Will Smith wear Ray-Ban too?
17. with who?
18. in what movie?
19. in what year?
numbered_answers:
1. their eyes hurt
2. a movie star
3. sunglasses
4. Klieg eyes
5. the Klieg brothers
6. 1961
7. Audrey Hepburn
8. Ray-Ban
9. Jake and Elwood
10. The Blue Brothers
11. 1979
12. yes
13. Aviator
14. Top Gun
15. 1986
16. yes
17. Tommy Lee Jones
18. Men in Black
19. 1997