Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: Treat with Respect The speed with which Man is changing the face of Earth has outstripped all the mighty processes of nature put together. In his haste to supply himself with increasing quantities of Earth's treasures he risks destroying one he greatly needs, his natural surroundings. Some countries set aside unspoiled areas of natural beauty. prefix = st1 /Canadahas the largest system of national parks in the world, 29 in all covering about 13 million hectares, preserving the different landscapes and the plant and animal life. Other countries are restoring areas which have been reduced to waste land by mining. At Broken Hill in Australiadrifting sand from rock crushing turned the area into a desert swept by sand storms. This is now being irrigated, fertilized and planted with grass and trees. In Great Britain quarries and gravel pits are being filled in or made into lakes, industrial wasteland is being turned into playing fields and waste tips into sloping green hills. However Man tries to look after Earth, the fact is that he is using up at a great rate resources, especially fuel resources, which have taken millions of years to accumulate and which he cannot renew. Yet every day the Earth receives a huge supply of energy from the Sun. Man has made several experiments in using solar energy to heat furnaces , cookers, and water-distillers. In space technology, e.g. on satellites, solar cells convert sunlight into electricity. Houses and offices have been designed which are centrally heated by water or air heated by the sunlight. When Man can trap and store this energy, so that he can use it exactly as he needs it, he will have not only an endless supply, but a clean and safe one.

Answer: According to this selected passage, which energy is considered to be endless, clean and safe?

Question: It has been reported that the R497K polymorphism of the epidermal growth factor receptor (EGFR) gene has attenuated functions in ligand binding, tyrosine kinase activation, and growth stimulation. On other hand, EGFR gene mutations at kinase domain in non-small cell lung cancer (NSCLC) have been examined for their ability to predict sensitivity to gefitinib or erlotinib. We investigated the EGFR mutations and/or R497K polymorphism statuses in 225 surgically treated NSCLC cases. 192 adenocarcinoma cases were included. The presence or absence of EGFR polymorphism of exon 13 was analyzed by PCR-RFLP method. EGFR mutations at kinase domain were found from 95 of 225 lung cancer patients. In 86.2% of patients, homo- or heterozygous Lys497 allele was present. No correlation existed between R497K EGFR genotype and clinico-pathological features, such as gender, smoking status, and pathological subtypes. EGFR mutation status was not correlated with R497KEGFR genotype of lung cancers. In node-negative patients, R497KEGFR genotype was not correlated with disease outcome. In node-positive patients, however, R497K EGFR was significantly associated with better overall survival. This association was attributable to neo-adjuvant or adjuvant chemotherapy. In 46 total gefitinib treated NSCLC patients, the prognosis was not different between the EGFR wild type (GG) patients and AG+AA patients. R497KEGFR polymorphism might be associated with favorable prognosis of advanced lung cancers and correlated with chemosensitivity.

Answer: Mutations in which gene determine response to both erlotinib and gefitinib?

Question: I'm not so sure I like my friends any more. I used to like them-to be honest. We'd have lunch, talk on the phone or exchange emails, and they all seemed normal enough. But then came Face Book, and I was introduced to a sad fact: many of my friends have dark sides that they had kept from me. Today my friends show off the more unpleasant aspects of their personalities via FaceBook. No longer hidden, they're thrown in my face like TV commercials -unavoidable and endless advertisements for the worst of their personalities. Take Fred. If you were to have lunch with him, you'd find him warm, and self-effacing .Read his FaceBook and you'll realize he's an unbearable, food-obsessed boring man. He'd pause to have a cup of coffee on his way to save a drowning man-and then write about it. Take Andy. You won't find a smarter CEO anywhere, but now he's a CEO without a company to run. So he plays Mafia Wars on FaceBook. He's doing well-level 731. Thanks to FaceBook, I know he's playing about 18 hours a day. Andy, you've run four companies-and this is how you spend your downtime? What happned to golf?What happened to getting another job? Take Liz. She is positive that the flu vaccine will kill us all and that we should avoid it. And then comes Chris who likes to post at least 20 times a day on every website he can find, so I get to read his thoughts twice, once on FaceBook and once on Twitter. In real life, I don't see these sides of people. Face to face, my friends show me their best. They're nice, smart people. But face to FaceBook, my friends is like a blind date which goes horribly wrong. I'm left with a dilemma. Who is my real friend?Is it the Liz I have lunch with or the anti-vaccine madman on FaceBook? Is it the Fred I can grab a sandwich with or the Fred who weeps if he's at a party and the wine isn't up to his standard?

Answer:
Who is opposed to the flu vaccine in the text?