You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a scientific passage and an answer, generate a question for the given answer.

Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Why? The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

New input: Passage: If you look at the map pictured below, you will see that the lithosphere is divided into plates ( Figure below ). There are a dozen major and several minor plates. Each plate is named for the continent or ocean basin it contains. Some plates are made of all oceanic lithosphere. A few are all continental lithosphere. But most plates are made of a combination of both. Notice the locations where the most earthquake epicenters are found. Answer: continental and oceanic lithosphere
Solution:
Most plates are made up of a combination of what?