In this task, you are given an abstract of article. Your task is to generate title for this article. Preferred titles are under thirty words.

To live or to die? This crucial question eloquently reflects the dual role of Ca2+ in living organisms survival factor or ruthless killer. It has long been known that Ca2+ signals govern a host of vital cell functions and so are necessary for cell survival. However, more recently it has become clear that cellular Ca2+ overload, or perturbation of intracellular Ca2+ compartmentalization, can cause cytotoxicity and trigger either apoptotic or necrotic cell death.
Calcium: Regulation of cell death: the calciumapoptosis link