Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does myeloid knockout of HIF-1 markedly affect hemorrhage/resuscitation-induced inflammation and hepatic injury?
Answer: Here, deleting HIF-1 in myeloid cells and thereby in Kupffer cells was not protective after H/R. This data indicates that other factors, such as NF- B, due to its upregulated phosphorylation in WT and KO mice, contrary to HIF-1 , are rather key modulators of inflammation after H/R in our model.

Answer: no

Question: Question: Is cerebral acetylcholinesterase activity decreased in MS patients with cognitive impairment?
Answer: In the patient group regional AChE activities had inverse correlations with Word learning and MMSE (Mini-Mental State Examination) scores. In the group of cognitively deteriorated MS patients no change in cerebral AChE activity, compared with controls, was observed, but within the patient group more pronounced cognitive symptoms were associated with higher cerebral AChE activity.

Answer: no

Question: Question: Is routine contrast enema required for all infants prior to ostomy reversal : A 10-year single-center experience?
Answer: Routine CE is not required prior to small bowel ostomy reversal in infants. We recommend judicious use of enema studies in patients with NEC and high likelihood of stricture.

Answer:
no