TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Although peak finding in next-generation sequencing (NGS) datasets has been addressed extensively, there is no consensus on how to analyze and process biological replicates. Furthermore, most peak finders do not focus on accurate determination of enrichment site widths and are not widely applicable to different types of datasets. We developed JAMM (Joint Analysis of NGS replicates via Mixture Model clustering): a peak finder that can integrate information from biological replicates, determine enrichment site widths accurately and resolve neighboring narrow peaks. JAMM is a universal peak finder that is applicable to different types of datasets. We show that JAMM is among the best performing peak finders in terms of site detection accuracy and in terms of accurate determination of enrichment sites widths. In addition, JAMM's replicate integration improves peak spatial resolution, sorting and peak finding accuracy. JAMM is available for free and can run on Linux machines through the command line: [Link]

SOLUTION: Which peak calling algorithm employs mixture model clustering under the hood?

PROBLEM: An Australian inventor has designed and built an environmentally friendly ferry that uses solar and wind power to transport people around Sydney Harbor. Robert Dane and his Solar Sailor were given the top prize at the Australian Design Awards recently. The Solar Sailor has been in use for six months. It uses four sources of energy for its power -- solar, wind, battery power with stored solar energy and a fuel generator in store all controlled by computers. The ferry can travel up to 7.5 knots on just wind and solar power. It's solar wings and fiberglass solar panels which not only take in sunlight and store it in batteries, but also act as sails. "We angle our solar panels to the sun in two planes , which increases the amount of energy we get from the sun by 40 percent," Dane says. "And also we can use that same structure to do another job, which is also the sail, and so these wing sails actually push the ferry forward just like a soft sail does." Computers check the sun and wind and angle the solar wings to take in the most sunlight. If there isn't much wind or it is a cloudy day, energy stored in the batteries runs the electric motor for up to five hours. "If the batteries are too low, then the computer turns the generator on so the boat is always able to meet a commercial schedule, or get from point A to point B no matter what," Dan explains. Dane got his idea for the Solar Sailor from a book on insects. He was amazed how insects use their wings to collect solar energy to warm themselves. "When I read that, I realized there was a good example in nature for what we were going to do, which was to use a solar wing to collect solar energy and also to sail," he says.

SOLUTION: What is the Solar Sailor?

PROBLEM: In October, Ubayd Steed, a sixth grader in Philadelphia, Pennsylvania, was taking a math test when he noticed a classmate looking at his paper. " I quickly turned my paper over," he said. Later that day, Ubayd met the cheater and told him not to do it again. Unfortunately, Ubayd' s experience is not unusual. Whether it's kids copying class -mates' answers during tests or friends sharing homework, cheating happens in schools every day. Experts say the behavior starts in the lower grades. Surveys show that one in three elementary students admits to cheating. Jacob Harder, a fourth grader in Ware, Massachusetts, has had classmates ask to copy his homework. "I wouldn't want to just tell them the answers," he says. So instead, he explains the task and encourages his classmates to do it themselves. But many kids find it hard to say no. "l hear from kids all the time, ' I can' t say no to a friend,'" says Eric Anderman, a professor at The Ohio State University who studies cheating in school. He says it' s important to say no from the start. "Then you _ , and the other kid gets the message," he says. Plus, he points out, "a real friend is not going to disown you because he or she couldn't copy your math homework." The kids doing the copying may feel they need to cheat to be accepted by other kids. And some students may cheat simply because others do. "If you' re in an atmosphere where cheating is common, you may think that if you don' t cheat, you' re at a disadvantage," says Michael Josephson, founder of the Josephson Institute of Ethics. But Josephson says students shouldn't think that way. "There are a lot of things kids do," he says. "You have to decide what kind of person you' re going to be." When school becomes too challenging, Anderman suggests going to the teacher rather than relying on the work of others. "It' s good to ask for help," he says.

SOLUTION:
Who advises kids to turn to teachers for help when they fall behind in studies'?