You will be given a definition of a task first, then some input of the task.
Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).

Abstract: We succeeded in reproducing an eczematous lesion on the apparently normal skin of a patient with atopic dermatitis by scratching and continuous application of an ointment containing ferritin-labelled mite antigen. Percutaneous entry of mite antigen was demonstrated in skin biopsies by Fe-staining. Scratched skin first showed an urticarial reaction typical of type I allergy which later changed into an eczematous reaction typical of type IV allergy. This change was also shown histologically.
Which is the apt title for the abstract? option1: Challenge reactions in atopic dermatitis after percutaneous entry of mite antigen. option2: Malignant melanoma and squamous cell carcinoma in a patient treated for severe pustular psoriasis.
Output:
Challenge reactions in atopic dermatitis after percutaneous entry of mite antigen.