Problem: Ehrlich's approach of systematically varying the chemical structure of synthetic compounds and measuring the effects of these changes on biological activity was pursued broadly by industrial scientists, including Bayer scientists Josef Klarer, Fritz Mietzsch, and Gerhard Domagk. This work, also based in the testing of compounds available from the German dye industry, led to the development of Prontosil, the first representative of the sulfonamide class of antibiotics. Compared to arsphenamine, the sulfonamides had a broader spectrum of activity and were far less toxic, rendering them useful for infections caused by pathogens such as streptococci. In 1939, Domagk received the Nobel Prize in Medicine for this discovery. Nonetheless, the dramatic decrease in deaths from infectious diseases that occurred prior to World War II was primarily the result of improved public health measures such as clean water and less crowded housing, and the impact of anti-infective drugs and vaccines was significant mainly after World War II.
What was the name of the first sulfonamine antibiotic?
The answer is the following: Prontosil

Problem: Valencia was founded as a Roman colony in 138 BC. The city is situated on the banks of the Turia, on the east coast of the Iberian Peninsula, fronting the Gulf of Valencia on the Mediterranean Sea. Its historic centre is one of the largest in Spain, with approximately 169 hectares; this heritage of ancient monuments, views and cultural attractions makes Valencia one of the country's most popular tourist destinations. Major monuments include Valencia Cathedral, the Torres de Serrans, the Torres de Quart, the Llotja de la Seda (declared a World Heritage Site by UNESCO in 1996), and the Ciutat de les Arts i les Ciencies (City of Arts and Sciences), an entertainment-based cultural and architectural complex designed by Santiago Calatrava and Felix Candela. The Museu de Belles Arts de Valencia houses a large collection of paintings from the 14th to the 18th centuries, including works by Velazquez, El Greco, and Goya, as well as an important series of engravings by Piranesi. The Institut Valencia d'Art Modern (Valencian Institute of Modern Art) houses both permanent collections and temporary exhibitions of contemporary art and photography.
On what river is Valencia located?
The answer is the following: Turia

Problem: Uranium metal reacts with almost all non-metal elements (with an exception of the noble gases) and their compounds, with reactivity increasing with temperature. Hydrochloric and nitric acids dissolve uranium, but non-oxidizing acids other than hydrochloric acid attack the element very slowly. When finely divided, it can react with cold water; in air, uranium metal becomes coated with a dark layer of uranium oxide. Uranium in ores is extracted chemically and converted into uranium dioxide or other chemical forms usable in industry.
What is a notable form uranium ore is converted into after extraction?
The answer is the following: uranium dioxide

Problem: From earliest days, Virginia, and Richmond in particular, have welcomed live theatrical performances. From Lewis Hallam's early productions of Shakespeare in Williamsburg, the focus shifted to Richmond's antebellum prominence as a main colonial and early 19th century performance venue for such celebrated American and English actors as William Macready, Edwin Forrest, and the Booth family. In the 20th century, Richmonders' love of theater continued with many amateur troupes and regular touring professional productions. In the 1960s a small renaissance or golden age accompanied the growth of professional dinner theaters and the fostering of theater by the Virginia Museum, reaching a peak in the 1970s with the establishment of a resident Equity company at the Virginia Museum Theater (now the Leslie Cheek) and the birth of Theatre IV, a company that continues to this day.
What is Virginia Museum Theater known as today?
The answer is the following:
Leslie Cheek