Given the task definition and input, reply with output. In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Tics can be associated with altered behaviors that arise at a certain time. When the symptoms appear between 35 and 45 years, according to Shapiro's classification, to what tic we refer?
Options: <1> Simple acute tic. <2> Chronic simple tic. <3> Huntington's Korea. <4> Chronic multiple tic. <5> Multiple tic of the adult.
3