Given the question: Information: - A valley is a low area between hills, often with a river running through it. - The Chienti is a river in the Marche region of Italy. Its source is near Serravalle di Chienti in the Appennino Umbro-Marchigiano mountains in the province of Macerata. The river flows northeast through the mountains past Muccia and enters and exits a small reservoir before entering Lago di Pievefavera. After exiting Lago di Pievefavera, the river continues flowing northeast before being joined by the Fiastrone at Belforte del Chienti. The river continues flowing northeast past Tolentino before being joined by the Fiastra south of Macerata. The river flows east near Corridonia and forms the border between the province of Macerata and the province of Fermo before flowing into the Adriatic Sea near Civitanova Marche. - Umbria, is a region of historic and modern central Italy. It is the only Italian region having neither a coastline nor a border with other countries. It includes the Lake Trasimeno, Marmore's Falls, and is crossed by the River Tiber. The regional capital is Perugia. Umbria is known for its landscapes, traditions, history, culinary delights, artistic legacy, and influence on culture. - The March of Ancona (also Anconetana) was a frontier march centred on the city of Ancona and, then, Macerata in the Middle Ages. Its name is preserved as an Italian region today, the Marches, and it corresponds to almost the entire modern region and not just the Province of Ancona. - The province of Ancona is a province in the Marche region of central Italy. Its capital is the city of Ancona, and the province borders the Adriatic Sea. The city of Ancona is also the capital of Marche. - An administrative division, unit, entity, area or region, also referred to as a subnational entity, constituent unit, or country subdivision, is a portion of a country or other region delineated for the purpose of administration. Administrative divisions are granted a certain degree of autonomy and are usually required to manage themselves through their own local governments. Countries are divided up into these smaller units to make managing their land and the affairs of their people easier. For example, a country may be divided into provinces, which, in turn, are divided into counties, which, in turn, may be divided in whole or in part into municipalities; and so on. - Le Marche ( Italian pronunciation : ( marke ) ) , or the Marches / mrtz / , is one of the twenty regions of Italy . The name of the region derives from the plural name of marca , originally referring to the medieval March of Ancona and nearby marches of Camerino and Fermo . The region is located in the Central area of the country , bordered by Emilia - Romagna and the republic of San Marino to the north , Tuscany to the west , Umbria to the southwest , Abruzzo and Lazio to the south and the Adriatic Sea to the east . Except for river valleys and the often very narrow coastal strip , the land is hilly . A railway from Bologna to Brindisi , built in the 19th century , runs along the coast of the entire territory . Inland , the mountainous nature of the region , even today , allows relatively little travel north and south , except by twisting roads over the passes . - The regions of Italy (Italian: "regioni") are the first-level administrative divisions of Italy, constituting its second NUTS administrative level. There are 20 regions, of which five are constitutionally given a broader amount of autonomy granted by special statutes. - Italy, officially the Italian Republic, is a unitary parliamentary republic in Europe. Located in the heart of the Mediterranean Sea, Italy shares open land borders with France, Switzerland, Austria, Slovenia, San Marino and Vatican City. Italy covers an area of and has a largely temperate seasonal climate and Mediterranean climate; due to its shape, it is often referred to in Italy as "lo Stivale" (the Boot). With 61 million inhabitants, it is the fourth most populous EU member state. - The province of Fermo is a province in the Marche region of central Italy. It was established in 2004 and became operational in 2009. Its administrative centre and provincial capital is the city of Fermo (population of 37,728 inhabitants as of 2015). Other major cities include Porto Sant'Elpidio (25,434 inhabitants), Porto San Giorgio (16,372 inhabitants), Sant'Elpidio a Mare (17,020 inhabitants), and Montegranaro (13,428 inhabitants). As of 2015, the province has a population of 176,380 inhabitants and spans an area of , giving it a population density of 204.44 inhabitants per square kilometre. It contains 40 "comuni". - Ancona ((elbow)) is a city and a seaport in the Marche region in central Italy, with a population of c. 101,997 . Ancona is the capital of the province of Ancona and of the region. - In the history of Europe, the Middle Ages or medieval period lasted from the 5th to the 15th century. It began with the fall of the Western Roman Empire and merged into the Renaissance and the Age of Discovery. The Middle Ages is the middle period of the three traditional divisions of Western history: classical antiquity, the medieval period, and the modern period. The medieval period is itself subdivided into the Early, High, and Late Middle Ages. - Fermo (ancient: Firmum Picenum) is a town and "comune" of the Marche, Italy, in the Province of Fermo. - Camerino is a town in the province of Macerata, Marche, central-eastern Italy. It is located in the Apennines bordering Umbria, between the valleys of the rivers Potenza and Chienti, about from Ancona. - The (plural: "") is a basic administrative division in Italy, roughly equivalent to a township or municipality. - Picenum was a region of ancient Italy. The name is an exonym assigned by the Romans, who conquered and incorporated it into the Roman Republic. Picenum was the "Regio V" in the augustan territorial organization of Italy. Picenum was also the birthplace of such roman notables as Pompey the Great and his father Pompeius Strabo. It was situated in what is now Marche and the northern part of Abruzzo. The Piceni or Picentes were the native population of Picenum, but they were not of uniform ethnicity. They maintained a religious centre in Cupra Marittima, in honor of the goddess Cupra. - The province of Macerata is a province in the Marche region of Italy. Its capital is the city of Macerata. The province includes 57 comunes (Italian: "comuni") in the province, see Comunes of the Province of Macerata. Located between the rivers Potenza ("Flosis") and Chienti, both of which originate in the province, the city of Macerata is located on a hill. - Macerata is a city and "comune" in central Italy, the county town of the province of Macerata in the Marche region. Together with the modern town, sprawling on the plain below, it has a population of about 43,000. What is the relationship between 'marche' and 'region of italy'?
The answer is:
instance of