Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

[EX Q]: Context: In eukaryotic cells, there are two sub-pathways of nucleotide excision repair (NER), the global genome (gg) NER and the transcription-coupled repair (TCR). TCR can preferentially remove the bulky DNA lesions located at the transcribed strand of a transcriptional active gene more rapidly than those at the untranscribed strand or overall genomic DNA. This strand-specific repair in a suitable restriction fragment is usually determined by alkaline gel electrophoresis followed by Southern blotting transfer and hybridization with an indirect end-labeled single-stranded probe. Here we describe a new method of TCR assay based on strand-specific-PCR (SS-PCR). Using this method, we have investigated the role of DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the phosphatidylinositol 3-kinase-related protein kinases (PIKK) family, in the TCR pathway of UV-induced DNA damage. Although depletion of DNA-PKcs sensitized HeLa cells to UV radiation, it did not affect the ggNER efficiency of UV-induced cyclobutane pyrimidine dimers (CPD) damage. We postulated that DNA-PKcs may involve in the TCR process. To test this hypothesis, we have firstly developed a novel method of TCR assay based on the strand-specific PCR technology with a set of smart primers, which allows the strand-specific amplification of a restricted gene fragment of UV radiation-damaged genomic DNA in mammalian cells. Using this new method, we confirmed that siRNA-mediated downregulation of Cockayne syndrome B resulted in a deficiency of TCR of the UV-damaged dihydrofolate reductase (DHFR) gene. In addition, DMSO-induced silencing of the c-myc gene led to a decreased TCR efficiency of UV radiation-damaged c-myc gene in HL60 cells. On the basis of the above methodology verification, we found that the depletion of DNA-PKcs mediated by siRNA significantly decreased the TCR capacity of repairing the UV-induced CPDs damage in DHFR gene in HeLa cells, indicating that DNA-PKcs may also be involved in the TCR pathway of DNA damage repair. By means of immunoprecipitation and MALDI-TOF-Mass spectrometric analysis, we have revealed the interaction of DNA-PKcs and cyclin T2, which is a subunit of the human transcription elongation factor (P-TEFb). While the P-TEFb complex can phosphorylate the serine 2 of the carboxyl-terminal domain (CTD) of RNA polymerase II and promote transcription elongation. A new method of TCR assay was developed based the strand-specific-PCR (SS-PCR). Our data suggest that DNA-PKcs plays a role in the TCR pathway of UV-damaged DNA. One possible mechanistic hypothesis is that DNA-PKcs may function through associating with CyclinT2/CDK9 (P-TEFb) to modulate the activity of RNA Pol II, which has already been identified as a key molecule recognizing and initializing TCR.
Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
[EX A]: the transcribed strand

[EX Q]: Context: Methicillin-resistant Staphylococcus aureus (MRSA) is a common multidrug-resistant (MDR) pathogen. We herein discussed MRSA and its infections in Krasnoyarsk, Siberian Russia between 2007 and 2011. The incidence of MRSA in 3,662 subjects was 22.0% and 2.9% for healthcare- and community-associated MRSA (HA- and CA-MRSA), respectively. The 15-day mortality rates for MRSA hospital- and community-acquired pneumonia (HAP and CAP) were 6.5% and 50%, respectively. MRSA CAP cases included pediatric deaths; of the MRSA pneumonia episodes available, 27.3% were associated with bacteremia. Most cases of HA-MRSA examined exhibited ST239/spa3(t037)/SCCmecIII.1.1.2 (designated as ST239Kras), while all CA-MRSA cases examined were ST8/spa1(t008)/SCCmecIV.3.1.1(IVc) (designated as ST8Kras). ST239Kras and ST8Kras strongly expressed cytolytic peptide (phenol-soluble modulin , PSM; and -hemolysin, Hld) genes, similar to CA-MRSA. ST239Kras pneumonia may have been attributed to a unique set of multiple virulence factors (MVFs): toxic shock syndrome toxin-1 (TSST-1), elevated PSM/Hld expression, -hemolysin, the staphylococcal enterotoxin SEK/SEQ, the immune evasion factor SCIN/SAK, and collagen adhesin. Regarding ST8Kras, SEA was included in MVFs, some of which were common to ST239Kras. The ST239Kras (strain OC3) genome contained: a completely unique phage, Sa7-like (W), with no att repetition; S. aureus pathogenicity island SaPI2R, the first TSST-1 gene-positive (tst+) SaPI in the ST239 lineage; and a super copy of IS256 (22 copies/genome). ST239Kras carried the Brazilian SCCmecIII.1.1.2 and United Kingdom-type tst. ST239Kras and ST8Kras were MDR, with the same levofloxacin resistance mutations; small, but transmissible chloramphenicol resistance plasmids spread widely enough to not be ignored. These results suggest that novel MDR and MVF+ HA- and CA-MRSA (ST239Kras and ST8Kras) emerged in Siberian Russia (Krasnoyarsk) associated with fatal pneumonia, and also with ST239Kras, a new (Siberian Russian) clade of the ST239 lineage, which was created through stepwise evolution during its potential transmission route of Brazil-Europe-Russia/Krasnoyarsk, thereby selective advantages from unique MVFs and the MDR.
Question: What is MRSA?
[EX A]: mrsa

[EX Q]: Context: Stu Shepard (Colin Farrell) is an arrogant New York City publicist who is contemplating cheating on his wife Kelly (Radha Mitchell). He calls Pam (Katie Holmes), a young actress, from a phone booth on a side street. When a delivery man (Dell Yount) tries to deliver a free pizza to the booth, Stu rudely dismisses him. After the phone call with Pam, the phone rings and Stu answers it. The caller (voice of Kiefer Sutherland), says that Stu should have accepted the pizza as it would have "kept his strength up for what comes next". He warns Stu not to leave the booth. Stu, again dismissive, is skeptical toward the mystery caller. The caller says that he will say 'hi' to Kelly for him, then hangs up, leaving Stu visibly concerned.The unseen man calls back and reveals that he had previously setup two other dishonest individuals in a similar situation, where he gave them a chance to redeem themselves but since both refused he had to kill them. One was a pedophile, and the other was a business executive who used inside information to cash in his stock options before the company share price collapsed (and refused the caller's request to share the proceeds with regular investors who got burned on that stock). The caller tells Stu that he must tell Kelly and Pam the truth: that he is cheating. The man calls Pam, puts Stu on speakerphone, and he tells her that Stu is married and does not want anything with Pam except to sleep with her. He then tells Stu to call his wife and tell her the truth, or else he will. Angrily, Stu does so.Before he has a chance to tell Kelly the truth, Stu is distracted by three prostitutes who want to use the phone. The prostitutes become hostile due to Stu's refusal to leave the booth, and they start banging against the glass. Stu becomes agitated and finally hangs up on his wife and yells at the prostitutes to leave him alone. As the three girls leave, the man calls and warns Stu that if he hangs up again, he will shoot him. Stu does not believe him but is convinced when the man cocks his rifle. Stu gets scared, warning him that if he shoots, the cops will arrive. However, the sniper proves him to be wrong by shooting a toy robot next to the booth without anyone noticing. The caller continues to mock Stu's faith that the caller is not capable.The situation escalates further when the prostitutes and their pimp, Leon (John Enos III), approach the booth and demand that Stu leave. Terrified that he will be shot, Stu refuses. The impasse between Stu and Leon escalates to the point of Leon breaking into the booth with a bat and attacking Stu. The sniper tells Stu he can help him and Stu says "yes". Leon is shot in the back by the sniper, horrifying the prostitutes, who accuse Stu.The police arrive and Stu is instantly the suspect. He doubts that they will find any evidence to suggest his guilt to the murder, but later finds out the sniper has planted a gun in the phone booth's roof, on top of the light panel that could be used as evidence in Leon's murder. Captain Ed Ramey (Forest Whitaker) arrives tries to negotiate with Stu to exit the booth but he says he cannot get off the call and he is talking to his "psychiatrist". Multiple news vans arrive, and reporters begin filming the situation, putting pressure on the police to deal with the situation without appearing trigger-happy. The caller continues to taunt Stu by telling him to take hold of the planted gun, or he would "Blow him (Ramey) Away!" but Stu refuses, knowing the police will likely shoot him.Kelly arrives at the scene and the sniper makes Stu confess to her about his infidelity, which Stu does. The man asks Stu to choose between Pam and Kelly, threatening to kill one of them to eliminate further temptation. The unseen caller tells Stu that there are policemen right now trying
Question: Who is Stu told to choose between?
[EX A]:
pam and kelly