In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: The DNA-dependent RNA polymerase of eukaryotes and prokaryotes is inhibited by:
Options: <1> Rifampicin <2> -Amanitin. <3> Oligomycin. <4> Streptomycin. <5> Actinomycin D.
5