In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: The increase in standard free energy of ATP hydrolysis depends, among others, on the following structural characteristic:
Options: <1> Its polar character. <2> Its amphipathic nature <3> Its stabilization by resonance. <4> Of the phosphoryl group number it contains. <5> Of the cation with which the soluble salt forms.
3

Question: If you want to study the efficacy and safety of a new cytostatic for a specific oncological process and, at the same time, contrast the efficacy that adds a new monoclonal antibody to this treatment, what would be the most appropriate study design?
Options: <1> Parallel test. <2> Cross test <3> Factorial test. <4> Sequential test. <5> Test of n = 1.
3

Question: A 24-year-old woman with two weekly episodes of headache lasting between one and three days, hemicranial, intense, accompanied by sono and photophobia and nausea. As a preventive treatment, I would NOT consider one of these drugs:
Options: <1> Propranolol <2> Flunarizine <3> Carbamazepine <4> Topiramate. <5> Nadolol
3