In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Input: Consider Input: Paragraph: CD13/Aminopeptidase N (CD13) is known to play an important role in tumour cell invasion. We examined whether basic fibroblast growth factor (bFGF) is involved in the regulation of CD13 expression in human melanoma cells. 1F6 human melanoma cells were stably transfected with constructs encoding either the 18 kDa (18kD) or all (ALL) bFGF isoform proteins. We observed highly increased CD13 mRNA and protein expression in the 1F6 clones regardless of the overexpression of either the 18kD or all isoform proteins. Neutral aminopeptidase activity was increased five-fold and could be inhibited by bestatin and the CD13-neutralising antibody WM15. The enhanced invasion through Matrigel, but not migration in a wound assay, was efficiently abrogated by both bestatin and WM15. Upregulation of CD13 expression was the result of increased epithelial and myeloid promoter activity up to 4.5fold in 1F6-18kD and 1F6-ALL clones. Interestingly, in a panel of human melanoma cell lines, a significant correlation (r 2 0.883, Po0.05) between bFGF and CD13 mRNA and protein expression was detected. High bFGF and CD13 expression were clearly related with an aggressive phenotype. Taken together, our data indicate that high bFGF expression upregulates CD13 expression in human melanoma cells by activating both the myeloid and the epithelial CD13 promoter. In addition, we show that high bFGF and CD13 expression results in enhanced invasive capacity and metastatic behaviour of human melanoma cells.
Title: CD13/Aminopeptidase N overexpression by basic fibroblast growth factor mediates enhanced invasiveness of 1F6 human melanoma cells

Output: False

Input: Consider Input: Paragraph: A rapid one-step reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay targeting the pol-integrase gene was developed to detect human immunodeficiency virus type 1 (HIV-1) group M. This HIV-1 RT-LAMP assay is simple and rapid, and amplification can be completed within 35 min under isothermal conditions at 60 C. The 100% detection limit of HIV-1 RT-LAMP was determined using a standard strain (WHO HIV-1 [97/656]) in octuplicate and found to be 120 copies/ml. The RT-LAMP assay was evaluated for use for clinical diagnosis using plasma samples collected from 57 HIV-1-infected and 40 uninfected individuals in Cameroon, where highly divergent HIV-1 strains are prevalent. Of the 57 samples from infected individuals, 56 harbored group-M HIV-1 strains, such as subtypes A, B, G, F2, and circulating recombinant forms (CRFs) 01, 02, 09, 11, 13; all were RT-LAMP positive. One sample harboring group-O HIV-1 and the 40 HIV-1-uninfected samples were RT-LAMP negative. These findings indicate that HIV-1 RT-LAMP can detect HIV-1 group-M RNA from plasma samples rapidly and with high sensitivity and specificity. These data also suggest that this RT-LAMP assay can be useful for confirming HIV diagnosis, particularly in resource-limited settings.
Title: Rapid detection of human immunodeficiency virus type 1 group M by a reverse transcription-loop-mediated isothermal amplification assay

Output: True

Input: Consider Input: Paragraph: Each problem that I solved became a rule, which served afterwards to solve other problems." -Rene Descartes the management of large-scale chemical, biological, radiological, nuclear, and explosives (CBRNE) events with mass casualties. These projects are funded by Defence Research and Development Canada, an agency within the Federal Department of National Defence, within its CBRNE Research and Technology Initiative (CRTI) preparing Canada's CBRNE response capabilities. Each project involves numerous public and private civilian partners as well as university partners, which is the category to which our team belongs. We are subcontracted by an industry client in charge of developing the software. When an adverse event escalates into a criminal investigation, it becomes very difficult to control and combine information into a manageable format. Numerous professionals representing different responder agencies, public health authorities, and others are involved, or become involved as the magnitude of an adverse event with mass casualties unfolds. In such events, chaos and uncertainty prevail; things happen very quickly, well before the first responders arrive on the scene, and last until a clearer picture of the nature and scope of the event can be formed, a command post has been set up, and a responsible action plan can be formulated and executed. The combined role of the first-responder teams is to preserve life, property, and equipment, while preventing the damage from spreading, providing triage to casualties on Usability in Government Systems.
Title: Emergency Response in Simulated Terrorist Attacks: Usability Lessons Learned 7
Output: False