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It should have your name, address, and cell phone info on it in case they get separated from you. Keep a recent picture of your child on you. Do not let children out of your sight, and instruct them to stay close to you at all times. For example, at security, say "you'll have to take off your shoes to put them through the scanner, but don't worry, you'll get them back!" Before take-off, say "The plane is going to go really fast and shake a little, but it's okay, nothing bad will happen." Keep them involved during the scary parts by giving them a small but important job to do, such as putting item bins on the conveyor belt or turning off the electronics before take-off. Kids will like the responsibility of preparing and carrying their own luggage. It can also help them feel more confident if they feel nervous about their adventure. Supervise packing so that everything that your child needs makes it into their bag, and don't forget a luggage tag with your name and phone number for each bag. Minimize the amount of metal in clothing and shoes to save time at security. Planes can be cold, so have the kids wear a jacket or keep one in their bag. Bring earache drops and show them how to pop their ears to minimize ear pain from high altitude. If they feel nauseated, Dramamine or Emetrol can help. Consult with your doctor before using medications that your child has not used before. Keep wet wipes, napkins, hand sanitizer, bandages, sick bags, and Pull-Ups in your carry-on. Don't rely on the flight attendants to take care of your child's mishaps as they have many other passengers to attend to.
Put a "Help, I'm lost" card in your child's pocket. Walk them through the major steps of air travel like security and take-off. Let them pack their own bag. Dress in lightweight, comfortable clothing and slip-on shoes. Tell them that ear or tummy pain during the plane ride is only temporary. Bring a cleanup kit for messes and accidents.