This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Example Input: For example, the full name of Oda Nobunaga would be "Oda Kazusanosuke Saburo Nobunaga" (), in which "Oda" is a clan or family name, "Kazusanosuke" is a title of vice-governor of Kazusa province, "Saburo" is a formal nickname (yobina), and "Nobunaga" is an adult name (nanori) given at genpuku, the coming of age ceremony. A man was addressed by his family name and his title, or by his yobina if he did not have a title. However, the nanori was a private name that could be used by only a very few, including the Emperor.
Example Output: What did Nobunaga mean?

Example Input: The joint mission began when Soyuz 19 was first launched on July 15, 1975 at 12:20 UTC, and the Apollo craft was launched with the docking module six and a half hours later. The two craft rendezvoused and docked on July 17 at 16:19 UTC. The three astronauts conducted joint experiments with the two cosmonauts, and the crew shook hands, exchanged gifts, and visited each other's craft.
Example Output: Soyuz 19 took off from Earth on what date?

Example Input: Housekeeping genes are critical for carrying out basic cell functions and so are expressed at a relatively constant level (constitutively). Since their expression is constant, housekeeping genes are used as experimental controls when analysing gene expression. Not all essential genes are housekeeping genes since some essential genes are developmentally regulated or expressed at certain times during the organism's life cycle.
Example Output:
What type of genes are necessary for performing basic cell functions?