In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Ex Input:
A reversed passive hemagglutination (I~PHA) method was developed for the detection of bovine eoronavirus in fecal specimens. Sheep erythrocytes fixed with glutaraldehyde, and then treated with tannic acid were coated with anti-bovine coronavirus rabbit antibodies purified by affinity chromatography using bovine eoronavirus linked to Sepharose 4B. The RPHA test was carried out by a microtiter method. Erythrocytes coated with purified specific antibodies were agglutinated by bovine coronavirus, but not by bovine rotavirus or enterovirus. The reaction was inhibited by antiserum to bovine coronavirus, confirming the specificity of the reaction. The I~PIIA test detected bovine coronavirus in 13 of 22 fecal specimens (59 per cent), from natural cases of diarrhea, while the positive rates were only 14 per cent (3/22) and 22 per cent (5/22) for immunofluorescent staining of primary cultures of calf kidney cells infected with the specimens, and immune electron microscopy respectively. The advantages of the I~PHA method are its simplicity, high sensitivity and rapidity.

Ex Output:
Archives of Virology Detection of Bovine Coronavirus in Feces by Reversed Passive Hemagglutination

Ex Input:
To investigate the efficacy of intracerebral (IC) immunization in preventing viral spread in the brain, we immunized mice with inactivated rabies virus via the subcutaneous (SC) or IC route, followed by administration of a lethal dose of rabies virus (challenge virus standard strain), directly into the brains of immunized mice. Progressive paralytic neurological signs were observed in control and 75% of SC immunized mice, whereas only 20% of IC immunized mice exhibited symptoms. Neutralizing antibody titers in blood plasma were significantly elevated in SC and IC immunized mice, with the highest levels seen in IC immunized mice. Analysis of whole brain lysates revealed a strong induction of immunoglobulin in the brains of IC immunized mice that had virus neutralizing activity. Histopathological examination of brain tissue revealed mild encephalitis and disseminated viral antigen in control and SC immunized mice, but rare in IC immunized mice. These results suggest that IC immunization induces a preventive humoral immune response against intracerebrally inoculated rabies virus. Induction of neutralizing antibody in cerebrospinal fluid represents a putative therapeutic measure for the treatment of rabid animals and humans.

Ex Output:
Intracerebral vaccination suppresses the spread of rabies virus in the mouse brain

Ex Input:
KEYWORDS Respiratory viruses Laboratory diagnosis Molecular methods Polymerase chain reaction Molecular tests for the detection of respiratory viruses are more sensitive and can detect more viruses than the traditional methods of culture and antigen detection. There are now several molecular assays available, cleared by the Food and Drug Administration, which differ with respect to the viruses detected, instrumentation, throughput, hands-on time, the need for separate nucleic acid extraction, and sensitivity for certain groups of viruses. Issues associated with molecular tests for respiratory viruses include: possible falsenegative results due to sequence variants; the inability of many assays to discriminate rhinoviruses from enteroviruses; the ability to detect viral nucleic acids in asymptomatic individuals; and the increased prevalence of coinfections.

Ex Output:
Molecular Detection of Respiratory Viruses