Context and question: Antibacterial antibiotics are commonly classified based on their mechanism of action, chemical structure, or spectrum of activity. Most target bacterial functions or growth processes. Those that target the bacterial cell wall (penicillins and cephalosporins) or the cell membrane (polymyxins), or interfere with essential bacterial enzymes (rifamycins, lipiarmycins, quinolones, and sulfonamides) have bactericidal activities. Those that target protein synthesis (macrolides, lincosamides and tetracyclines) are usually bacteriostatic (with the exception of bactericidal aminoglycosides). Further categorization is based on their target specificity. "Narrow-spectrum" antibacterial antibiotics target specific types of bacteria, such as Gram-negative or Gram-positive bacteria, whereas broad-spectrum antibiotics affect a wide range of bacteria. Following a 40-year hiatus in discovering new classes of antibacterial compounds, four new classes of antibacterial antibiotics have been brought into clinical use in the late 2000s and early 2010s: cyclic lipopeptides (such as daptomycin), glycylcyclines (such as tigecycline), oxazolidinones (such as linezolid), and lipiarmycins (such as fidaxomicin).
Which type of antibiotic goes after the cell membrane?
Answer: polymyxins
Context and question: The domestication of large animals (c. 8000 BC) resulted in a dramatic increase in social inequality in most of the areas where it occurred; New Guinea being a notable exception. Possession of livestock allowed competition between households and resulted in inherited inequalities of wealth. Neolithic pastoralists who controlled large herds gradually acquired more livestock, and this made economic inequalities more pronounced. However, evidence of social inequality is still disputed, as settlements such as Catal Huyuk reveal a striking lack of difference in the size of homes and burial sites, suggesting a more egalitarian society with no evidence of the concept of capital, although some homes do appear slightly larger or more elaborately decorated than others.
What settlement featured equal sized homes with little evidence of capital?
Answer: Catal Huyuk
Context and question: Albert the Great wrote that wisdom and understanding enhance one's faith in God. According to him, these are the tools that God uses to commune with a contemplative. Love in the soul is both the cause and result of true understanding and judgement. It causes not only an intellectual knowledge of God, but a spiritual and emotional knowledge as well. Contemplation is the means whereby one can obtain this goal of understanding. Things that once seemed static and unchanging become full of possibility and perfection. The contemplative then knows that God is, but she does not know what God is. Thus, contemplation forever produces a mystified, imperfect knowledge of God. The soul is exalted beyond the rest of God's creation but it cannot see God Himself.
What cannot see God itself?
Answer:
The soul