Problem: Dame Helen Lydia Mirren, (nee Mironoff; born 26 July 1945) is an English actor. Mirren began her acting career with the Royal Shakespeare Company in 1967, and is one of the few performers who have achieved the Triple Crown of Acting. She won the Academy Award for Best Actress in 2007 for her performance as Queen Elizabeth II in The Queen and received the Olivier Award for Best Actress and Tony Award for Best Actress in a Play for the same role in The Audience. Mirren's other Academy Award nominations include The Madness of King George (1994), Gosford Park (2001) and The Last Station (2009).

In 2015, Mirren reunited with her former assistant Simon Curtis on Woman in Gold, co-starring Ryan Reynolds. The film was based on the true story of Jewish refugee Maria Altmann, who, together with her young lawyer Randy Schoenberg, fought the Austrian government to be reunited with Gustav Klimt's painting of her aunt, the famous Portrait of Adele Bloch-Bauer I. The film received mixed reviews from critics, although Mirren and Reynold's performances were widely praised. A commercial success, Woman in Gold became one of the highest-grossing specialty films of the year. The same year, Mirren appeared in Gavin Hood's thriller Eye in the Sky (2015), in which she played as a military intelligence officer who leads a secret drone mission to capture a terrorist group living in Nairobi, Kenya. Mirren last film that year was Jay Roach's biographical drama Trumbo, co-starring Bryan Cranston and Diane Lane. The actress played Hedda Hopper, the famous actress and gossip columnist, in the film, which received generally positive reviews from critics and garnered her a 14th Golden Globe nomination. Mirren's only film of 2016 was Collateral Beauty, directed by David Frankel. Co-Starring Will Smith, Keira Knightley, and Kate Winslet, the ensemble drama follows a man who copes with his daughter's death by writing letters to time, death, and love. The film earned largely negative reviews from critics, who called it "well-meaning but fundamentally flawed." In 2017, Mirren narrated Cries from Syria, a documentary film about the Syrian Civil War, directed by Evgeny Afineevsky. Also that year, she made an uncredited cameo appearance in F. Gary Gray's The Fate of the Furious, the eighth installment in The Fast and the Furious franchise, playing Magdalene, the mother of Owen and Deckard Shaw. Mirren had a larger role in director Paolo Virzi's English-language debut The Leisure Seeker, based on the 2009 novel of the same name. On set, she was reunited with Donald Sutherland with whom she had not worked again since Bethune: The Making of a Hero (1990), portraying a terminally ill couple who escape from their retirement home and take one last cross-country adventure in a vintage van. At the 75th awards ceremony, Mirren received her 15th Golden Globe nomination. In 2018, Mirren portrayed heiress Sarah Winchester in the supernatural horror film Winchester: The House That Ghosts Built, directed by The Spierig Brothers. She will also play Mother Ginger in Lasse Hallstrom and Disney's adaptation of The Nutcracker, titled The Nutcracker and the Four Realms, and is expected to appear in the ensemble film Berlin, I Love You and the French crime thriller film Anna, the latter directed and written by Luc Besson.

Did she receive any awards between 2015 to present?

Answer with quotes: At the 75th awards ceremony, Mirren received her 15th Golden Globe nomination.

Problem: Henry Gustav Molaison (February 26, 1926 - December 2, 2008), known widely as H.M., was an American memory disorder patient who had a bilateral medial temporal lobectomy to surgically resect the anterior two thirds of his hippocampi, parahippocampal cortices, entorhinal cortices, piriform cortices, and amygdalae in an attempt to cure his epilepsy. Although the surgery was partially successful in controlling his epilepsy, a severe side effect was that he became unable to form new memories. H.M. was widely studied from late 1957 until his death in 2008. His case played an important role in the development of theories that explain the link between brain function and memory, and in the development of cognitive neuropsychology, a branch of psychology that aims to understand how the structure and function of the brain relates to specific psychological processes.

Henry Molaison was born on February 26, 1926, and experienced intractable epilepsy that has sometimes been attributed to a bicycle accident at the age of seven. (This accident was initially reported to have occurred at age nine, but was corrected by the patient's mother at a later stage.) He had partial seizures for many years, and then several tonic-clonic seizures following his 16th birthday. In 1953, he was referred to William Beecher Scoville, a neurosurgeon at Hartford Hospital, for treatment. Scoville localized Molaison's epilepsy to his left and right medial temporal lobes (MTLs) and suggested surgical resection of the MTLs as a treatment. On September 1, 1953, at the age of 27, Molaison's bilateral medial temporal lobe resection included the removal of the hippocampal formation and adjacent structures, including most of the amygdaloid complex and entorhinal cortex. His hippocampi appeared entirely nonfunctional because the remaining 2 cm of hippocampal tissue appeared to have atrophied and because the entire entorhinal cortex, which forms the major sensory input to the hippocampus, was destroyed. Some of his anterolateral temporal cortex was also destroyed. After the surgery, which was partially successful in its primary goal of controlling his epilepsy, Molaison developed severe anterograde amnesia: although his working memory and procedural memory were intact, he could not commit new events to his explicit memory. According to some scientists, he was impaired in his ability to form new semantic knowledge, but researchers argue over the extent of this impairment. He also had moderate retrograde amnesia, and could not remember most events in the one- to two-year period before surgery, nor some events up to 11 years before, meaning that his amnesia was temporally graded. However, his ability to form long-term procedural memories was intact; thus he could, for example, learn new motor skills, despite not being able to remember learning them. The case was first reported in a paper by Scoville and Brenda Milner in 1957. Near the end of his life, Molaison regularly filled in crossword puzzles. He was able to fill in answers to clues that referred to pre-1953 knowledge. For post-1953 information he was able to modify old memories with new information. For instance, he could add a memory about Jonas Salk by modifying his memory of polio. He died on December 2, 2008.

How did epilepsy effect him?

Answer with quotes:
He had partial seizures for many years, and then several tonic-clonic seizures following his 16th birthday.