In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: The maturation process for the dendritic cell involves important changes in its physiology, such as:
Options: <1> Decreased expression of the CCR7 marker. <2> Reduction of endocytic capacity. <3> Decreased expression of histocompatibility molecules. <4> Synthesis of IL-13. <5> Reduction of CD40 expression.
2