Q: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Question: In relation to toxoplasmosis and pregnancy, indicate which of the following options is true:
Options: <1> Placental transmission to the fetus can occur. <2> The rate of antibodies should be detected at the beginning of pregnancy and, in their absence, vaccination with killed virus vaccine should be carried out. <3> The infection is less severe but more frequent the younger the pregnant woman is. <4> In our environment, the main cause of infection is the coexistence and management of domestic birds. <5> The infection occurs intrapartum, favored by the rupture of the amniotic sac.
A:
1