Teacher:In this task, you need to Translate Czech text to English.
Teacher: Now, understand the problem? Solve this instance: Fluorovan deriv t na fenylov skupin substituovan ho 4-azasteroidu obecn ho vzorce I, kde znamen ==== jednoduchou nebo dvojnou vazbu, R H, C.sub.1-4.n.alkyl, R.sub.f.n. a R'.sub.f.n. na sob nez visle C.sub.1-4.n.alkyl, substituovan alespo jedn m atomem F, R.sub.1.n. a R.sub.2.n. na sob nez visle H, fenyl, C.sub.1-4.n.alkyl, pop pad substituovan alespo jedn m atomem F, halogen, CN, OR.sub.4.n., kde R.sub.4.n. znamen H nebo C.sub.1-4.n.alkyl, SR.sub.5.n., kde R.sub.5.n. znamen H nebo C.sub.1-4.n.alkyl, a COR.sub.6.n., kde R.sub.6.n. znamen OR.sub.4.n., kde R.sub.4.n. m shora uveden vznam nebo znamen C.sub.1-4.n.alkyl, pop pad substituovan alespo jedn m atomem F, inhibuje testosteron 5.alfa.-redukt zu, a je proto vhodn pro vrobu farmaceutick ho prostedku k oUetov n akn , seborrhoey, nadm rn ho ensk ho ochlupen nebo mu sk ho pleUat n , polycystick ho onemocn n vaje n k a rakoviny prsu nebo pro oUetov n a/nebo chemoprevenci benign hyperplasie prostaty nebo rakoviny prostaty.Student:
The present invention relates to a phenyl substituted 4-azasteroid fluoro derivative of the general formula I, in which ==== denotes a single or double bond R represents hydrogen, or alkyl containing 1 to 4 carbon atoms, Rif a R'if represent independently on each other alkyl containing 1 to 4 carbon atoms being substituted with at least one fluorine atom, Ri1 a Ri2 denote independently on each other hydrogen, phenyl, alkyl containing 1 to 4 carbon atoms being optionally substituted with at least one fluorine atom, a halogen, CN, ORi4 wherein Ri4 represents hydrogen or alkyl containing 1 to 4 carbon atoms, SRi5, wherein Ri5 denotes hydrogen or alkyl containing 1 to 4 carbon atoms, and CORi6 wherein Ri6 represents ORi4 wherein Ri4 is as specified above or it may represent alkyl containing 1 to 4 carbon atoms being optionally substituted with at least one fluorine atom. The above described derivative inhibits testosterone 5alpha-reductase and is therefore suitable for preparing a pharmaceutical composition intended for treating acne, seborrhea, female hirsutism and male pattern baldness, polycystic ovary disease and breast cancer or for treating and/or chemoprevention of benign prostatic hyperplasia and prostatic cancer.