Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

[Q]: This release makes no mention of the costs of the drugs compared in this study, even though the drugs have been in use for years and are widely available. Since the study is a comparison of various treatments for this form of cancer, it seems relevant to offer a cost comparison as well as a comparison of efficacy. It appears that the high dose methotrexate is given over a 24-hour period, presumably in the hospital, while the standard methotrexate is given as a single dose. Also, the high dose methotrexate isfollowed by leucovorin administration while the standard dose is not. According to the site GoodRx, the cost for methotrexate in low-dose (2.5 mg) pill form averages out to about $50 for a month's supply. Newer, injectable variations of the drug cost upwards of $500 a month for the 25 mg dose. The release states that patients receiving high doses of the drug methotrexate "had a significantly better outcome, by 5 to 6 percent" than did patients receiving the current standard of care, which is gradually escalating doses of the drug. The release also explains that patients nine years old or younger who were also treated with a steroid called decadron (dexamethasone) forhalf as long as normal (14 versus 28 days) benefited from the treatment while patients 10 and older did not. We're not sure of the meaning behind these results as portrayed in the release. Which outcome was better by 5 or 6 percent? The study has several. Does that mean the relapse rate was reduced or is it the event free survival that was better? It would be more meaningful to readers if the release had included the actual relapse and event free survival rates for each group analyzed in terms most people can understand. For example: "relapse rates were 5 percent lower in Group X compared to Group Y." We'll give this category a satisfactory rating largely due to the release including information that patients 10 and older receiving dexamethasone "were at much higher risk for a debilitating bone condition called osteonecrosis," although we would have been happier if that greater risk would have been quantified. However, the published study explains that there were toxicity problems beyond that of dexamethasone and the release would have been stronger including that information as well. The release stated the study was randomized and controlled, and provides a broad overview of the study design, for which we give the release a borderline satisfactory under this criteria. However, these are thesuperficial results. On deeper delving into the study methodology, the statistical significances of the results were very close to notstatistically significant. This is due to their planned interim stopping of the treatment and the fact that they were looking at multiple outcomes in multiple groups. This release doesn't demonstrate disease-mongering. While the release does say that this clinical trial was run by the Children's Oncology Group, which is funded by the National Cancer Institute and the National Institutes of Health, it makes no mention of possible conflicts of interest. Compounding that is the fact that the published study says, "Disclosures provided by the authors are available with this article at www.jco.org," but that information is behind the journal's paywall for most readers, so it's unknown if there is, or is not, a conflict. It appears as though five of the authors (out of a total of about 20) have some conflicts of interest, mostly from several types of drug company payments. The release is comparing the efficacy of treatment regimens using different drugs so alternative treatmentsfor B-acute lymphoblastic leukemia are noted. The release makes clear at the end that the treatment of this disease is improving thanks to refinement of the use of existing drug treatments, meaning that they are readily available for patient use. The release suggests the study findings could change the way childhood leukemia is treated. Modifying existing treatments to enhance a patient's survival is certainly novel enough to warrant a release. There is no use of unjustifiable language in this release. However, the tone may be a bit overly optimistic given the study findings.
[A]: Relapses of childhood leukemia improve with high doses of common chemo drug

[Q]: A nun attends a mass led by Pope Benedict XVI at the Garden of Gethsemane at the foot of the Mount of Olives in Jerusalem May 12, 2009, where it is believed Jesus had his final prayer before he was betrayed and arrested. REUTERS/Baz Ratner The vow of chastity taken by the world's 95,000 Catholic nuns carries with it an increased risk of breast, ovarian and uterine cancers all of which are more common in women who do not have children. It is a problem that has been recognized for hundreds of years. In 1713, Italian physician Bernadino Ramazzini reported nuns had extremely high rates of the "accursed pest," breast cancer. Kara Britt of Monash University and Roger Short of the University of Melbourne, writing in The Lancet medical journal, argued that taking modern contraceptive pills could be one answer. Lack of pregnancy and lactation means childless women have more menstrual cycles, which increases cancer risk, while those who have children further decrease their risk if they have first babies while young, have several children and breastfeed. Overall mortality in women using the contraceptive pill is around 12 percent lower than in those who have never used it and the risk of developing ovarian and endometrial cancers falls by 50 to 60 percent, the authors said. "If the Catholic Church could make the oral contraceptive pill freely available to all its nuns, it would reduce the risk of those accursed pests, cancer of the ovary and uterus, and give nuns' plight the recognition it deserves," the doctors said. Although the Catholic Church condemns all forms of contraception, barring abstinence, the doctors argued that using the pill might still be possible under regulations on birth control set out by Pope Paul VI in Humanae Vitae in 1968. This document stated that "the Church in no way regards as unlawful therapeutic means considered necessary to cure organic diseases, even though they also have a contraceptive effect." Of course, the pill can also carry its own dangers, such as the risk of blood clots with the combined oestrogen-progestogen version, so the suitability of nuns would have to be assessed according to their individual medical histories, the doctors added.
[A]: Vow of chastity and the pill may keep nuns healthy.

[Q]: The announcement by the world's largest fast-food chain comes as more companies respond to government and consumer pressure to address the global obesity epidemic. McDonald's, which often bears the brunt of criticism over the restaurant industry's penchant for tempting diners with indulgent and often high-calorie food, said it would offer the option in all of its 20 major global markets by 2020. McDonald's also vowed to promote and market only water, milk and juice as the beverages in its popular Happy Meals for children as part of its announcement at the Clinton Global Initiative annual meeting in New York on Thursday. Waist sizes around the world are increasing, setting off alarms in public health circles. In recent years, the U.S. food industry has begun yielding to pressure from government, parents and consumers seeking to slim down adults and children. Sugary sodas have been yanked from public schools; sugar, sodium and calorie levels have been reduced in products, and calorie counts have been posted on some restaurant menus. The Center for Science in the Public Interest, a nonprofit that has tangled with McDonald's over everything from fattening food to the marketing of Happy Meals, approved of the company's move to add more fruits and vegetables to the menu. Still, it says the company and its rivals have a long way to go in terms of offering healthier options. "McDonald's slow march toward healthier meals made a major advance today, but a long road lies ahead for the company," CSPI said in a statement. McDonald's is seen as something of a trend setter among restaurant chains, but like many of its peers, it has tended to resist external efforts to force change. About one year ago McDonald's said it would begin listing calorie information on menus in some 14,000 U.S. restaurants and drive-throughs ahead of a national rule that would require larger restaurant chains to make such disclosures but months after other chains embraced the idea. In July 2011 it tweaked its popular Happy Meals for children - reducing the french fries portion by more than half and adding apples to every order. The move came after pressure from CSPI, parent groups and others. More than one-third of Americans are obese, and about 10 percent of the nation's healthcare bill is tied to obesity-related illnesses, such as Type 2 diabetes, heart disease and hypertension, according to the Organization for Economic Co-operation and Development. McDonald's said its announcement is part of a plan developed with the Alliance for a Healthier Generation, which was founded by the Clinton Foundation and American Heart Association, to increase customers' access to fruit and vegetables and help families and children to make informed eating and lifestyle choices.
[A]:
Want fruit with your burger? McDonald's expands anti-obesity push.