Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Approximately 10% of ALS patients have familial form of the disease. Numerous different gene mutations have been found in familial cases of ALS, such as mutations in superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43), fused in sarcoma (FUS), C9ORF72, ubiquilin-2 (UBQLN2), optineurin (OPTN) and others. Multiple animal models were generated to mimic the disease and to test future treatments. However, no animal model fully replicates the spectrum of phenotypes in the human disease and it is difficult to assess how a therapeutic effect in disease models can predict efficacy in humans. Importantly, the genetic and phenotypic heterogeneity of ALS leads to a variety of responses to similar treatment regimens. From this has emerged the concept of personalized medicine (PM), which is a medical scheme that combines study of genetic, environmental and clinical diagnostic testing, including biomarkers, to individualized patient care. In this perspective, we used subgroups of specific ALS-linked gene mutations to go through existing animal models and to provide a comprehensive profile of the differences and similarities between animal models of disease and human disease. Finally, we reviewed application of biomarkers and gene therapies relevant in personalized medicine approach. For instance, this includes viral delivering of antisense oligonucleotide and small interfering RNA in SOD1, TDP-43 and C9orf72 mice models. Promising gene therapies raised possibilities for treating differently the major mutations in familial ALS cases.
[EX A]: Which human disease is associated with mutated UBQLN2

[EX Q]: The 1,204-seat arena at Tundra Oil & Gas Place is home to the Virden Oil Capitals of the Manitoba Junior Hockey League, Virden Oil Kings of the North Central Hockey League, Virden Golden Bears of the Manitoba High School Hockey League, local minor hockey, and local figure skating programs.
[EX A]: What team uses Tundra Oil & Gas Place?

[EX Q]: Vivi Mac, an amazing artist from France, can use nearly any kind of food to create detailed celebrity portraits .Although she has yet to _ her short-lived work of arts in a proper art gallery, Vivi Mac has already made a name for herself online. We've seen some amazing food artists in the past, but none are quite like this one .Karen Eland is a master coffee painter, Elisabetta Rogai uses wine as her medium ,Kelly McCollam uses food colouring to recreat classic paintings, but the self-taught Vivi Mac can take anything from chewing gum to milk and turn it into a fantastic portrait When working with liquids, Mac uses a simple plastic straw and her hands to guide the unusual .mediums around a plastic plate which acts as a painting. Just how she manages to capture the finest facial features is still a mistery to me, and I've seen videos of her doing it many times, Vivi Mac has never attended art school. She only used online resources like blogs and facebook to learn the basics of drawing and painting. She started out working with pens and paper, but soon realized drawing wasn't just creative enough for her. She got into speed painting and body painting, posting videos of her works on You Tube, but it wasn't until she began experimenting with different kinds of foods that her art got serious coverage. Photos and videos of her eatable celebrity portraits, like Bruce Lee in milk Ice Cube in crushed ice or Amy Winehouse in wine, became popular on the French inter-webs and changed Vivi Mac into an online celebrity.
[EX A]:
In which section of a website are we most likely to find the passage?