Definition: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
Input: Question: Do large deletions play a minor but essential role in congenital coagulation factor VII and X deficiencies?
Answer: Large deletions play a minor but essential role in the mutational spectrum of the F7 and F10 genes. Copy number analyses (e.g. MLPA) should be considered if sequencing cannot clarify the underlying reason of an observed coagulopathy. Of note, in cases of combined FVII/FX deficiency, a deletion of the two contiguous genes might be part of a larger chromosomal rearrangement.
Output:
yes