Given the task definition and input, reply with output. Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does pax6 influence expression patterns of genes involved in neuro- degeneration?
Answer: Presence of BDNF and TGF indicates association between them in glioblastoma-astrocytoma. Therefore, Pax6 seems to be involved directly with p53 and TGF mediated pathways and indirectly with redox-sensitive pathway regulation. The neurodegenerative markers S100, GFAP, BDNF, NGN2, p73, p73, observed downregulated in Pax6 knockdown condition suggest Pax6-mediated regulation of these markers. Observations enlighten Pax6-mediated influences on cascades of genes involved in growth, differentiation and maturation of neurons and glia.
yes