Text: Although people typically use the word ''antihistamine'' to describe drugs for treating allergies, doctors and scientists use the term to describe a class of drug that opposes the activity of histamine receptors in the body. In this sense of the word, antihistamines are subclassified according to the histamine receptor that they act upon. The two largest classes of antihistamines are H-antihistamines and H-antihistamines. Antihistamines that target the histamine H-receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing) as well as for insomnia. They are sometimes also used to treat motion sickness or vertigo caused by problems with the inner ear. Antihistamines that target the histamine H-receptor are used to treat gastric acid conditions (e.g., peptic ulcers and acid reflux). H-antihistamines work by binding to histamine H receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary nucleus in the brain; H-antihistamines bind to histamine H receptors in the upper gastrointestinal tract, primarily in the stomach.

Question: is histamine an agonist for h1 and h2 receptors?

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Answer: yes

Text: Boise State has won 1 NCAA team national championship.

Question: has boise state ever won a national championship?

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Answer: yes

Text: Since its debut on December 17, 1989, 639 episodes of The Simpsons have been broadcast. It is the longest-running American sitcom, and, in 2009, it surpassed Gunsmoke as the longest-running American scripted primetime television series in terms of seasons and in terms of episodes in 2018. The Simpsons Movie, a feature-length film, was released in theaters worldwide on July 27, 2007, and grossed over $527 million. On November 4, 2016, the series was renewed for a thirtieth season, extending the show to May 2019; it will premiere on September 30, 2018.

Question: is there going to be a 30th season of the simpsons?

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Answer: yes

Text: The human areola (areola mammae, /ril/ or /riol/) is the pigmented area on the breast around the nipple. Areola, more generally, is a small circular area on the body with a different histology from the surrounding tissue, or other small circular areas such as an inflamed region of skin.

Question: is the nipple and areola the same thing?

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- no
- yes
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Answer:
no