Give some stream of consciousness and then the answer. Dead zones are hypoxic (low-oxygen) areas in the world's oceans and large lakes, caused by "excessive nutrient pollution from human activities coupled with other factors that deplete the oxygen required to support most marine life in bottom and near-bottom water. (NOAA)". In the 1970s oceanographers began noting increased instances of dead zones. These occur near inhabited coastlines, where aquatic life is most concentrated. (The vast middle portions of the oceans, which naturally have little life, are not considered "dead zones".)

Answer this question: what causes a dead zone in the ocean?
The relevant information is: Dead zones are hypoxic (low-oxygen) areas in the world's oceans and large lakes, caused by "excessive nutrient pollution from human activities coupled with other factors that deplete the oxygen required to support most marine life in bottom and near-bottom water.
Therefore, the answer is excessive nutrient pollution from human activities coupled with other factors that deplete the oxygen required to support most marine life in bottom and near - bottom water.