In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Q: Question: In mitosis, the nuclear membrane disintegrates and spindle microtubules bind to the kinetochores in:
Options: <1> Cytokinesis <2> Prometaphase. <3> Metaphase <4> Interface. <5> Prophase.
A:
2