Rituximab has approved , and in April 2011 been investigated by the FDA , when used in combination with glucocorticoids in adult patients .
Rituximab was investigated and approved by the FDA in April 2011 when it has been applied in combination with glucocorticoids in adult patients .

Select your answer from the options. Do these sentences mean the same thing?
Available options:
(A). no
(B). yes
(A).