Answer the following question: Information: - A hamartoma is a benign , focal malformation that resembles a neoplasm in the tissue of its origin . This is not a malignant tumor , and it grows at the same rate as the surrounding tissues . It is composed of tissue elements normally found at that site , but which are growing in a disorganized mass. They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason ( incidentaloma ) . Choristomas , forms of heterotopia , are closely related benign tumors , found in abnormal locations . The two can be differentiated as follows : a hamartoma is an excess of normal tissue in a normal situation ( e.g. a birthmark on the skin ) , while a choristoma is an excess of tissue in an abnormal situation ( e.g. pancreatic tissue in the duodenum ) . - Overdiagnosis is the diagnosis of "disease" that will never cause symptoms or death during a patient's lifetime. Overdiagnosis is a side effect of screening for early forms of disease. Although screening saves lives in some cases, in others it may turn people into patients unnecessarily and may lead to treatments that do no good and perhaps do harm. Given the tremendous variability that is normal in biology, . For a large percentage of them, the most appropriate medical response is to recognize them as something that does not require intervention; but determining which action a particular finding warrants ("ignoring", watchful waiting, or intervention) can be very difficult, whether because the differential diagnosis is uncertain or because the risk ratio is uncertain (risks posed by intervention, namely, adverse events, versus risks posed by not intervening). - A symptom (from Greek , "accident, misfortune, that which befalls", from , "I befall", from - "together, with" and , "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease. A symptom is subjective, observed by the patient, and cannot be measured directly, whereas a sign is objectively observable by others. For example, paresthesia is a symptom (only the person experiencing it can directly observe their own tingling feeling), whereas erythema is a sign (anyone can confirm that the skin is redder than usual). Symptoms and signs are often nonspecific, but often combinations of them are at least suggestive of certain diagnoses, helping to narrow down what may be wrong. In other cases they are specific even to the point of being pathognomonic. - The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis. - A CT scan (often referred to as a CAT scan) makes use of computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of specific areas of a scanned object, allowing the user to see inside the object without cutting. - Medicine (British English ; American English ) is the science and practice of the diagnosis, treatment, and prevention of disease. The word "medicine" is derived from Latin "medicus", meaning "a physician". Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. - In medicine, an incidentaloma is a tumor ("-oma") found by coincidence (incidentally) without clinical symptoms or suspicion. Like other types of incidental findings, it is found during the course of examination and imaging for other reasons. It is a common occurrence: up to 7% of all patients over 60 may harbor a benign growth, often of the adrenal gland, which is detected when diagnostic imaging is used for the analysis of unrelated symptoms. With the increase of "whole-body CT scanning" as part of health screening programs, the chance of finding incidentalomas is expected to increase. 37% of patients receiving whole-body CT scans have abnormal findings that may need further evaluation. Since many incidentally found lesions may never cause disease, there is a risk of overdiagnosis. - A collection of essays by physician-writer Danielle Ofri, MD, PhD, Incidental Findings: Lessons from my Patients in the Art of Medicine is the story of Ofri practicing medicine in small towns across America, then returning to teach and practice at Bellevue Hospital, Americas oldest public hospital. Ofri writes about dealing with patients speaking every language and of the challenge of training the next generation of doctors. She also writes about her experience being a patient. What is the relationship between 'hamartoma' and 'disease'?
Answer:
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