Bill Veeck was born on February 9, 1914, in Chicago, Illinois. While Veeck was growing up in Hinsdale, Illinois, his father, William Veeck Sr., became president of the Chicago Cubs. Veeck Sr. was a local sports writer who wrote several columns about how he would have run the Cubs differently, and the team's owner, William Wrigley Jr., took him up on it. While growing up, the younger Veeck worked as a popcorn vendor for the Cubs.

In 1942, Veeck left Chicago and, in partnership with former Cubs star and manager Charlie Grimm, purchased the American Association Triple-A Milwaukee Brewers. After winning three pennants in five years Veeck sold his Milwaukee franchise in 1945 for a $275,000 profit. According to his autobiography Veeck - As in Wreck, Veeck claimed to have installed a screen to make the right field target a little more difficult for left-handed pull hitters of the opposing team. The screen was on wheels, so any given day it might be in place or not, depending on the batting strength of the opposing team. There was no rule against that activity as such, but Veeck then took it to an extreme, rolling it out when the opponents batted, and pulling it back when the Brewers batted. Veeck reported that the league passed a rule against it the very next day. However, extensive research by two members of the Society for American Baseball Research (SABR) suggests that this story was made up by Veeck. The two researchers could not find any references to a moveable fence or any reference to the gear required for a moveable fence to work. While a half-owner of the Brewers, Veeck served for nearly three years in the United States Marine Corps during World War II in an artillery unit. During this time a recoiling artillery piece crushed his leg, requiring amputation first of the foot, and shortly after of the leg above the knee. Over the course of his life he had 36 operations on the leg. He had a series of wooden legs and, as an inveterate smoker, cut holes in them to use as an ashtray.

What else did he do in Milwaukee
While a half-owner of the Brewers, Veeck served for nearly three years in the United States Marine Corps during World War II in an artillery unit.