Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Breakfast with Hunter (2003) is a documentary about the everyday life of gonzo-journalist Hunter S. Thompson by Wayne Ewing.

A: The Breakfast with Hunter is based upon what?
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Q: TransLink is urging customers to avoid non-essential travel today and to stay home where possible in the difficult weather conditions. TransLink chief executive officer Peter Strachan said bus and train services were continuing to run where possible, however all CityCat and CityFerry services had been cancelled until further notice. "These are extremely difficult conditions for South East Queensland---we are running essential services where possible but safety remains to be the most important," Mr Strachan said. "Severe weather and associated flooding has impacted on all modes of public transport, with bus, ferry and train services all impacted to varying degrees. "If you are planning to use public transport at anytime over the next few days, then I would recommend you check that your intended service is still running." Service disruptions for today include: l City network trains running hourly on all lines. l Bus diversions, delays and cancellations in some regions, particularly across Brisbane, Ipswich and the Sunshine Coast. l CityCat and CityFerry services cancelled. Queensland Rail Chief Executive Officer Paul Scurrah said rising waterways had closed some train lines, and road closures and damage to property throughout the South-East had contributed to a shortage of available rail employees. "We intend to run trains hourly on all lines, similar to the timetable we operate on Christmas Day. We will also be looking to run other additional services to meet demand as required. At this stage we will run services stopping at all stations which will depart at the same time on the hour, however, this is all subject to the weather conditions and the availability of traincrew." Mr Scurrah encouraged all customers to visit the Translink website for specific departure times for their station, and asked for patience in the event of delays. "Queensland Rail appreciates that reduced services may cause disruptions but it is simply unavoidable. We have a dedicated and experienced team monitoring the situation around the clock and will be working to reopen the network as soon as practicably possible," Mr Scurrah said. The latest service disruption information is available on the TransLink website www.translink.com.au.

A: Which means of transport is NOT available during the special period?
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Q: Neurofibromatosis type 1 (NF1) is characterized primarily by tumor formation in the nervous system, but patients report other neurological complications including pain and itch. Individuals with NF1 harbor 1 mutated NF1 allele causing heterozygous expression in all of their cells. In mice, Nf1 heterozygosity leads to hyperexcitability of sensory neurons and hyperproliferation of mast cells, both of which could lead to increased hypersensitivity and scratching in response to noxious and pruritic stimuli. To determine whether Nf1 heterozygosity may increase pain and itch behaviors independent of secondary effects of tumor formation, we used mice with a targeted, heterozygous Nf1 gene deletion (Nf1) that lack tumors. Nf1 mice exhibited normal baseline responses to thermal and mechanical stimuli. Moreover, similar to wild-type littermates, Nf1 mice developed inflammation-induced heatand mechanical hypersensitivity, capsaicin-induced nocifensive behavior, histamine-dependent or -independent scratching, and chronic constriction injury-induced cold allodynia. However, Nf1mice exhibited an attenuated first phase of formalin-induced spontaneous behavior and expedited resolution of formalin-induced heat hypersensitivity. These results are not consistent with the hypothesis that Nf1 heterozygosity alone is sufficient to increase pain and itch sensation in mice, and they suggest that additional mechanisms may underlie reports of increased pain and itch in NF1 patients. This study assessed whether Nf1 heterozygosity in mice increased hypersensitivity and scratching following noxious and pruritic stimuli. Using Nf1 mice lacking tumors, this study finds no increases in pain or itch behavior, suggesting that there is no predisposition for either clinical symptom solely due to Nf1 heterozygosity.

A:
Which is the gene mutated in type 1 neurofibromatosis?
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