Please answer correctly the following question related to the paragraph below. Which uncle doesn't take a drug that works slightly differently in many people? Uncle Tom and uncle Sam both have high cholesterol. Uncle Tom is on statin drugs and uncle Sam is not. Hint: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem.
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Answer: Sam

Please answer correctly the following question related to the paragraph below. Would particle B have higher or lower temperature than particle A? David is a physicist. He teaches school children how matters and energy work. One day he was teaching them about two particles of matter, particle A and particle B. Particle A moves faster, but particle B moves slower. He was showing the children about different characteristics of moving particles. Hint: No doubt you already have a good idea of what temperature is. You might say that it's how warm or cool something feels. In physics, temperature is defined as the average kinetic energy of the particles of matter. When particles of matter move more quickly, they have more kinetic energy, so their temperature is higher. With a higher temperature, matter feels warmer. When particles move more slowly, they have less kinetic energy on average, so their temperature is lower. With a lower temperature, matter feels cooler.
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Answer: lower

Please answer correctly the following question related to the paragraph below. Which country had more species of animals disappear? Belgium and France are two countries participating at a human health meeting. Belgium has a lower biodiversity, while France's biodiversity is much higher. Hint: Biodiversity's relevance to human health is becoming an international political issue, as scientific evidence builds on the global health implications of biodiversity loss. This issue is closely linked with the issue of climate change, as many of the anticipated health risks of climate change are associated with changes in biodiversity (e.g. changes in populations and distribution of disease vectors, scarcity of fresh water, impacts on agricultural biodiversity and food resources etc.). This is because the species most likely to disappear are those that buffer against infectious disease transmission, while surviving species tend to be the ones that increase disease transmission, such as that of West Nile Virus, Lyme disease and Hantavirus, according to a study done co-authored by Felicia Keesing, an ecologist at Bard College and Drew Harvell, associate director for Environment of the Atkinson Center for a Sustainable Future (ACSF) at Cornell University.The growing demand and lack of drinkable water on the planet presents an additional challenge to the future of human health. Partly, the problem lies in the success of water suppliers to increase supplies and failure of groups promoting preservation of water resources. While the distribution of clean water increases, in some parts of the world it remains unequal. According to the World Health Organisation (2018) only 71% of the global population used a safely managed drinking-water service.Some of the health issues influenced by biodiversity include dietary health and nutrition security, infectious disease, medical science and medicinal resources, social and psychological health. Biodiversity is also known to have an important role in reducing disaster risk and in post-disaster relief and recovery efforts.Biodiversity provides critical support for drug discovery and the availability of medicinal resources. A significant proportion of drugs are derived, directly or indirectly, from biological sources: at least 50% of the pharmaceutical compounds on the US market...
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Answer:
Belgium