Given a scientific passage and an answer, generate a question for the given answer.

Let me give you an example: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
The answer to this example can be: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Here is why: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

OK. solve this:
Passage: (left) The DNA double helix wraps around proteins (2) and tightly coils a number of times to form a chromosome (5). This figure shows the complexity of the coiling process. The red dot shows the location of the centromere, where the microtubules attach during mitosis and meiosis. (right) A representation of a condensed eukaryotic chromosome, as seen after the DNA has been copied. The chromosome is made of two identical, or sister, chromatids held together by a centromere. Answer: chromosome
Answer:
What genetic unit is formed when the dna double helix wraps around proteins and tightly coils a number of times?