Detailed Instructions: In this task, you are given two facts, and a multiple-choice question. Based on the given facts, answer the question with index of the correct option (e.g, "A").
Q: Fact1: disease-causing microbes have a negative impact on the body, Fact2: Microbes are microscopic, single-celled organisms without a nucleus., Question: What has a negative impact on the body? (A) photons (B) exposure to cold (C) abundant food (D) influenza orthomyxoviruses (E) disease-causing organisms (F) smallest agents of disease (G) rocks (H) a tree falling
A:
E