[Q]: Given the background: Cholesterol has been implicated in heart disease for decades. Atherosclerosis is a disorder of the arteries in which cholesterol and other materials are deposited on the interior of the arterial wall. These deposits lead to the formation of plaques that can restrict or even block the flow of blood through these blood vessels (see Figure below ). A decrease in the flow of blood can lead to high blood pressure and a lowered oxygen supply to the heart muscle. A complete blockage of blood flow to parts of the heart (a heart attack) can cause significant damage due to oxygen deprivation, in some cases leading to death. and the situation: Fred was a good athlete in his youth, and so was Vic. Fred started eating junk food and other fatty foods in his 30's. His cholesterol is very high now. Vic became a vegan later,and he is in a very good physical shape. Answer the following question: Which friend had a normal blood flow to the heart?
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[A]: Vic

[Q]: Given the background: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. and the situation: Brad and Henry were two old friends in their 70's. Brad had very high levels of cholesterol, while Henry was healthier and had normal levels of cholesterol. Answer the following question: Which friend takes an inhibitor of HMG-CoA reductase?
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[A]: Brad

[Q]: Given the background: The increase in electrons across the periodic table explains why elements go from metals to metalloids and then to nonmetals from left to right across the table. Look at period 2 in Figure below as an example. Lithium (Li) is a metal, boron (B) a metalloid, and fluorine (F) and neon (Ne) are nonmetals. The inner energy level is full for all four elements. This level has just one orbital and can hold a maximum of two electrons. The outer energy level is a different story. This level has four orbitals and can hold a maximum of eight electrons. Lithium has just one electron in this level, boron has three, fluorine has seven, and neon has eight. and the situation: James is memorizing the periodic table and some of the features of the elements on it. He is currently working on the fourth row which starts with Potassium (K) on the far left and ends with Krypton (Kr) to the far right. Answer the following question: Given Lithium (Li) and Neon (Ne) are in the same row of the periodic table, which element has more electrons, Lithium (Li) or Neon (Ne)?
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[A]: Neon (Ne)

[Q]: Given the background: Carbon dioxide is the most significant long-lived greenhouse gas in Earth's atmosphere. Since the Industrial Revolution anthropogenic emissions primarily from use of fossil fuels and deforestation have rapidly increased its concentration in the atmosphere, leading to global warming. Carbon dioxide also causes ocean acidification because it dissolves in water to form carbonic acid. and the situation: Ted and Larry studied environmental sciences. They are learning about greenhouse gasses this week. Ted reads about carbon dioxide, while Larry reads about methane gas. Answer the following question: Which student read less about anthropogenic emissions?
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[A]:
Larry