Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Paragraph: The coronavirus, which emerged in China late last year, has decimated global markets as it quickly moves around the world. It appeared poised for a spike in the United States, in part because of more testing to confirm cases. Florida late Sunday declared a public health emergency as it confirmed its first two cases. Trump administration officials worked Sunday to soothe nerves and calm fears that a global recession was looming, arguing that the public and media were over-reacting and saying that stocks would bounce back because the American economy was fundamentally strong. The total number of confirmed cases in the United States is more than 75 with two reported deaths, both in Washington state. Globally there have been more than 87,000 cases and nearly 3,000 deaths in 60 countries, according to the World Health Organization. In the United States, a cluster of cases is centered on a nursing home near Seattle. The Seattle and King County public health department confirmed late Sunday that a man in his 70s who was a resident of the LifeCare long-term care facility in Kirkland and had coronavirus had died the day before. On Saturday, the department had reported the first death of a coronavirus patient in the United States, a man in his 50s who was living in Kirkland - the same city where the nursing home is located. Six of the 10 confirmed coronavirus cases in Washington state have been residents or workers at LifeCare. State officials said an additional 27 residents of the nursing home and 25 staff members were reporting symptoms of the virus, which can be similar to that of the common flu. New York Governor Andrew Cuomo confirmed on Twitter his state's first coronavirus case, a woman in her 30s who caught the virus during a recent trip to Iran and was now in home quarantine. Cuomo did not say where the woman lived, but the New York Times reported she was in the Manhattan borough of New York City, citing state officials. "The patient has respiratory symptoms, but is not in serious condition and has been in a controlled situation since arriving in New York," Cuomo said. Stock markets plunged last week, with an index of global stocks setting its largest weekly fall since the 2008 financial crisis, and more than $5 trillion wiped off the value of stocks worldwide. A key energy conference in Houston that brings together oil ministers and energy firms was canceled on Sunday with the organizers of CERAWeek noting that border health checks were becoming more restrictive and companies had begun barring non-essential travel to protect workers. A world economy conference with Pope Francis due to take place in Italy later this month was also canceled. Trump said on Sunday that travelers to the United States from countries at high risk of coronavirus would be screened before boarding and on arrival, without specifying which countries. Delta Air Lines Inc said on Sunday it was suspending until May flights to Milan in northern Italy, where most of that country's coronavirus cases have been reported. Flights will continue to Rome. American Airlines Group Inc announced a similar move late on Saturday. The United States has 75,000 test kits for coronavirus and will expand that number "radically" in coming weeks, U.S. Health and Human Services Secretary Alex Azar told ABC's "This Week" on Sunday. Vice President Mike Pence, appointed last week to run the White House's coronavirus response, said the government had contracted 3M Co to produce an extra 35 million respiratory masks a month. He urged Americans not to buy the masks, which he said were only needed by healthcare workers. Honeywell International Inc is the other major U.S. mask producer. He also told Fox News that clinical trials of a coronavirus vaccine would start in six weeks but that a vaccine would likely not be available this season. Democrats, who will challenge Trump for the presidency in the Nov. 3 election, have criticized his administration for downplaying the crisis and not preparing for the disease to spread in the United States. Pence said Americans should brace for more cases but that the "vast majority" of those who contracted the disease would recover. "Other than in areas where there are individuals that have been infected with the coronavirus, people need to understand that for the average American, the risk does remain low. We're ready," Pence told NBC's "Meet the Press." Claim: Washington state confirms second U.S. coronavirus death; New York reports first case.
Health officials in Washington state said late Sunday that a nursing home resident had died after contracting coronavirus, while New York's governor confirmed his state's first positive case, as the virus moved out of its West Coast foothold.

Paragraph: Mentions cost for one year of Herceptin as $40,000-$50,000. Mentions quantitative benefit of 9 weeks of Herceptin vs. no Herceptin with certain chemotherapy. Also, while no women in the Herceptin group had cardiac failure at 3 years, the follow-up period may not be long-enough to determine the effects of chemotherapy and Herceptin on the heart. Mentions potential harms of Herceptin on the heart, especially when given after certain chemotherapy. The story does not mention that there were side effects with certain chemotherapy drugs and doses needed to be decreased during the course of the trial. One aspect of this trial focused on randomization of women with Her2/neu overexpression to 9 weeks of Herceptin or no Herceptin immediately following breast cancer surgery. The drug was given in conjunction with certain types of chemotherapy, but before radiation and chemotherapy regimens known to damage the heart. The journalist states the Herceptin was given "prior to chemotherapy", which is not completely accurate. There is an adequate mention of the study design and discussion of disease-free survival at 3 years follow-up. Good job putting the results into context of other trials, and into context of how this may or may not change providers' practice. The story could have better stated the limitations of analysis for such a small subgroup 116 in each arm. Appropriately discusses the percentage of women who are eligible for Herceptin due to overexpression of HER2/neu. The story would have been helped by some context for the risk these women face. As Herceptin is used earlier and earlier these women have less to gain because they have less risk to begin with. Relative risk reductions may be very high but the absolute is not as big. Sources in addition to study authors are cited. No mention that this trial was funded in part by pharmaceutical companies. Some study investigators also receive research funding drug companies. Other doctors cited express caution about the early results of Herceptin studies, so there is some balance to the piece. The women in this trial had undergone breast cancer surgery and those with ER+ tumors were taking Tamoxifen. This is not explicitly mentioned, only that treatment took place following surgery. Still OK. Herceptin is only FDA approved to treat advanced breast cancer, but is used in clinical trials in early-stage breast cancer. This is not mentioned in the story. Novel use of Herceptin for short-term treatment prior to anthracycline chemotherapy. No evidence that this story relies on a press release. Claim: Short stint of Herceptin holds promise for breast cancer
This story discusses the results of a recent study involving women with high-risk early breast cancer (node positive or >2cm, age younger than 66 there were 25 year olds on the trial). One aspect of this trial focused on the short-term use of Herceptin with chemotherapy. Women with overexpression of the HER2/neu gene, as measured by the CISH immunohistochemistry, were randomly assigned 9 weeks of Herceptin or no Herceptin immediately following breast cancer surgery and in conjunction with certain types of chemotherapy. This regimen of treatment differed from other trials in which Herceptin was given for 12 months following chemotherapy. In this study, the drug was given in conjunction with certain types of chemotherapy, but before radiation and chemotherapy regimens known to damage the heart. The journalist states the Herceptin was given "prior to chemotherapy," which is not completely accurate. Herceptin is only FDA approved to treat advanced breast cancer, but it is used in clinical trials in early-stage breast cancer. However, this is not mentioned in the story. There is adequate discussion of the study design and reporting of disease-free survival at 3 years follow-up. There was little discussion in the piece of the side effects of chemotherapy as reported in the trial, but the addition of Herceptin was the main focus of the story. While the journalist provides quantitative benefit of 9 weeks of Herceptin vs. no Herceptin, and notes no cardiac failure in the Herceptin group, the follow-up period of 3 years may not be long-enough to determine the effects of chemotherapy and Herceptin on the heart. Overall, the journalist did a good job describing the randomization, as well as putting the results into context of other trials, and into context of how this may or may not change providers' practice. The story could have better stated the limitations of analysis for such a small subgroup (116 in each arm). The small sample randomized to Herceptin certainly warrants more study, and although the relative benefits were large, these women still had fairly good recurrence free survival 80% w/o and 90% with so although it looks like that will translate to overall survival. The question for women with overexpression of the HER/neu gene is: How much do you want to do to avoid recurrence? Sources in addition to the study investigators are cited, which provides some balance to the piece, however, there is no mention that the trial was funded in part by pharmaceutical companies. Some study investigators also receive research funding from drug companies.

Paragraph: Exposure to essential oils can be fatal for cats and small animals. But there's not much scientific evidence about how risky essential oils are for cats, and what levels are safe. First, we'll take a look at what essential oils are. They're high concentrations of oils that occur naturally in plants. When mixed with solvents, essential oils can be diluted and defused throughout a room. They're used for aromatherapy and for medicinal purposes. Warnings that essential oils are harmful to cats have been circulating for years. And for good reason. One version that we found on social media warns that "all citrus" varieties of essential oils are toxic to cats. Among those listed is tea tree essential oil. Studies indicate that the warning is valid, but only when cats are exposed to the oils in large doses. The Science Behind Claims That Essential Oils Are Harmful to Cats The Oklahoma Animal Disease Diagnostic Laboratory published a study in 1998 that described how three purebred cats were poisoned by Australian tea tree oil. The cats' owner applied a topical ointment containing the oil directly to the cats to treat fleas. All three became sick within hours. Ultimately, two of the cats survived and one died. Tea tree oil is toxic to cats because of how they metabolize terpenes, the organic compounds that give essential oils their scents. And other essential oils, like eucalyptus oil, are very similar in composition. They can be toxic to cats for the same reason. Most cases of poisoning result from misuse (like applying the oil directly to the cat's fur). But cats can also be especially susceptible to high concentrations of defused tea tree essential oil because of cats' grooming habits, the study found: The terpenes in tea tree oil are rapidly absorbed through the skin and digestive tract because of their highly lipophilic nature. Toxicity from dermal exposure has not been produced in rabbits but may be possible. Cats may be more susceptible to tea tree oil toxicosis after topical application than are other species because of their grooming behavior. In this case, the cats had been shaved, so that tea tree oil was applied directly to the skin, enhancing dermal absorption. The flea bite lesions may have also increased dermal absorption somewhat. Further, grooming efficiency was probably augmented due to shaving, allowing cats to ingest a large amount of the oil applied To summarize essential oils like tea tree oil can be toxic to cats if they lick it from their fur, or even if it's absorbed through their skin. Some argue that highly defused, high-quality essential oil in a well-ventilated room is perfectly safe for pets. However, we weren't able to find any studies indicating that that's true, or at what levels essential oils are safe for cats. For those reasons, we're calling claims that some essential oils are toxic for cats "true." Comments Claim: Essential oils can kill cats and mall animals. Social media posts warn those with cats to avoid certain essential oils.
Essential Oils Are Harmful to Cats and Small Animals .