In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

[Q]: Objectives. To critically appraise the efficacy and safety of Kangfuxinye enema combined with mesalamine for the ulcerative colitis (UC) patients and in addition to grade the quality of evidence by using the GRADE (grading of recommendations, assessment, development, and evaluation) approach. Methods. A literature search was performed in the Cochrane Library, MEDLINE, EMBASE, CBM, CNKI, VIP, and WanFang Databases. The search restrictions were patients with UC and RCTs. Studies including other treatments except Kangfuxinye with mesalamine were excluded. Results. Nineteen studies met the inclusion criteria. We found significant benefits of Kangfuxinye combined with mesalamine against mesalamine alone in improving response rate as well as reducing the recurrence rate and inflammation rate; meanwhile, the increase of the adverse events rate was not observed. Furthermore, the symptoms remission rate and the cure time were insignificant statistically. Additionally, GRADE results indicated that the quality of evidence regarding the above 6 outcomes was rated from very low to moderate quality. Conclusions. Although Kangfuxinye enema seems effective and safe for treating UC patients in this systematic review, Kangfuxinye enema combined with mesalamine was weakly recommended due to very low to moderate quality of available evidence by the GRADE approach.
[A]: Kangfuxinye Enema Combined with Mesalamine for Ulcerative Colitis: A Systematic Review and GRADE Approach

[Q]: Background: Rhinovirus (RV), a major cause of respiratory infection in humans, imposes an enormous economic burden due to the direct and indirect costs associated with the illness. Accurate and timely diagnosis is crucial for deciding the appropriate clinical approach and minimizing unnecessary prescription of antibiotics. Diagnosis of RV is extremely challenging due to genetic and serological variability among its numerous types and their similarity to enteroviruses. Objective: We sought to develop a rapid nucleic acid test that can be used for the detection of Rhinovirus within both laboratory and near patient settings. Study design: We developed and evaluated a novel isothermal nucleic acid amplification method called Reverse Transcription Strand Invasion-Based Amplification (RT-SIBA) to rapidly detect Rhinovirus from clinical specimens. Result: The method, RT-SIBA, detected RV in clinical specimens with high analytical sensitivity (96%) and specificity (100%). The time to positive result was significantly shorter for the RV RT-SIBA assay than for a reference RV nucleic acid amplification method (RT-qPCR). Conclusion: The rapid detection time of the RV SIBA assay, as well as its compatibility with portable instruments, will facilitate prompt diagnosis of infection and thereby improve patient care.
[A]: Detection of human rhinoviruses by reverse transcription strand invasion based amplification method (RT-SIBA)

[Q]: Delivery of native or chemically modified recombinant proteins into mammalian cells shows 31 promise for functional investigations and various technological applications, but concerns 32 that sub-cellular localization and functional integrity of delivered proteins may be affected 33 remain high. Here, we surveyed batch electroporation as a delivery tool for single 34 polypeptides and multi-subunit protein assemblies of kinetochores, a spatially confined and 35 well-studied subcellular structures. After electroporation in human cells, recombinant 36 fluorescent Ndc80 and Mis12 multi-subunit complexes displayed native localization, 37 physically interacted with endogenous binding partners, and functionally complemented 38 depleted endogenous counterparts to promote mitotic checkpoint signaling and 39 chromosome segregation. Farnesylation is required for kinetochore localization of the 40 Dynein adaptor Spindly. In cells with chronically inhibited farnesyl transferase activity, in 41 vitro farnesylation and electroporation reconstituted robust kinetochore localization of 42 Spindly. Thus, electroporation is uniquely versatile for delivering synthetic and, as required, 43 chemically modified functional mimics of endogenous proteins, and is therefore a promising 44 tool for chemical and synthetic biology.
[A]:
Electroporated recombinant proteins as tools for in vivo functional