Select from options: Continue writing the next sentence.

How to diagnose bone cancer
Pay attention to bone pain.
One of the main symptoms of bone cancer is pain in the affected bone. It often grows worse over time.

Options: (I) You may notice the pain more at certain times, such as at night or when you're using the affected area. You might start limping if the cancer is in a leg bone.; (II) Whether the pain is from a bone tumor or it is due to cancer, bone pain produces a sharp pain that washes over the joint. This pain is constant and not alleviated by surgery.; (III) Each time a finger or hand or foot is moved, it can become affected. The pain may reach the joint or tendons of the affected hand, causing significant numbness or tingling.; (IV) Pain is a symptom of a variety of diseases, so you have to look for signs that your body is trying to suppress what is known as " bone intolerance. " begin your examination by going straight to the bone.;
Answer:
(I)