In this task, you are given a question and an answer, you would be asked to create the sentence based on the Question-Answer provided. It should be contained within the Question-Answer provided.

Question: The ileocecal valve, a sphincter, is usually in a constricted state, but when motility in the ileum increases, this sphincter relaxes, allowing food residue to enter the first portion of what? Answer: large intestine
The ileocecal valve, a sphincter, is usually in a constricted state, but when motility in the ileum increases, this sphincter relaxes, allowing food residue to enter the first portion of large intestine.