Context and question: A number of medications are being studied for multi drug resistant tuberculosis including: bedaquiline and delamanid. Bedaquiline received U.S. Food and Drug Administration (FDA) approval in late 2012. The safety and effectiveness of these new agents are still uncertain, because they are based on the results of a relatively small studies. However, existing data suggest that patients taking bedaquiline in addition to standard TB therapy are five times more likely to die than those without the new drug, which has resulted in medical journal articles raising health policy questions about why the FDA approved the drug and whether financial ties to the company making bedaquiline influenced physicians' support for its use
What drug in the running to treat multi drug resistant TB has already gotten FDA approval?
Answer: Bedaquiline
Context and question: Two major hardware revisions of the Xbox 360 have succeeded the original models; the Xbox 360 S (also referred to as the "Slim") replaced the original "Elite" and "Arcade" models in 2010. The S model carries a smaller, streamlined appearance with an angular case, and utilizes a redesigned motherboard designed to alleviate the hardware and overheating issues experienced by prior models. It also includes a proprietary port for use with the Kinect sensor. The Xbox 360 E, a further streamlined variation of the 360 S with a two-tone rectangular case inspired by Xbox One, was released in 2013. In addition to its revised aesthetics, Xbox 360 E also has one fewer USB port and no longer supports S/PDIF.
What video input format is not supported by the 360 E?
Answer: S/PDIF
Context and question: Federations often employ the paradox of being a union of states, while still being states (or having aspects of statehood) in themselves. For example, James Madison (author of the US Constitution) wrote in Federalist Paper No. 39 that the US Constitution "is in strictness neither a national nor a federal constitution; but a composition of both. In its foundation, it is federal, not national; in the sources from which the ordinary powers of the Government are drawn, it is partly federal, and partly national..." This stems from the fact that states in the US maintain all sovereignty that they do not yield to the federation by their own consent. This was reaffirmed by the Tenth Amendment to the United States Constitution, which reserves all powers and rights that are not delegated to the Federal Government as left to the States and to the people.
What is the foundation for federalist paper no. 39?
Answer:
it is federal, not national; in the sources from which the ordinary powers of the Government are drawn, it is partly federal, and partly national..