You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a scientific passage and an answer, generate a question for the given answer.

Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Why? The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

New input: Passage: Basic Principles of Gas Exchange Gas exchange during respiration occurs primarily through diffusion. Diffusion is a process in which transport is driven by a concentration gradient. Gas molecules move from a region of high concentration to a region of low concentration. Blood that is low in oxygen concentration and high in carbon dioxide concentration undergoes gas exchange with air in the lungs. The air in the lungs has a higher concentration of oxygen than that of oxygen-depleted blood and a lower concentration of carbon dioxide. This concentration gradient allows for gas exchange during respiration. Partial pressure is a measure of the concentration of the individual components in a mixture of gases. The total pressure exerted by the mixture is the sum of the partial pressures of the components in the mixture. The rate of diffusion of a gas is proportional to its partial pressure within the total gas mixture. This concept is discussed further in detail below. Answer: diffusion
Solution:
Gas exchange during respiration occurs primarily through what?