Information: - Indium is a chemical element with symbolIn and atomic number49. It is a post-transition metal that makes up 0.21parts per million of the Earth's crust. Very soft and malleable, Indium has a melting point higher than sodium and gallium, but lower than lithium and tin. Chemically, indium is similar to gallium and thallium, and it is largely intermediate between the two in terms of its properties. Indium was discovered in 1863 by Ferdinand Reich and Hieronymous Theodor Richter by spectroscopic methods. They named it for the indigo blue line in its spectrum. Indium was isolated the next year. - Indium-111 is an isotope of indium with a radioactive half-life of 2.80 days, making it useful as a radioactive tracer. It is made for this use by the Nordion(Canada) Inc. unit of Nordion, Inc. as indium-111 chloride solution, and shipped to several firms which sterilize the pure solution, combine it with carrier compounds if needed, and repackage it for medical and industrial uses. - An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized (as in the case of autoimmune diseases) are also epitopes. - Nordion Inc. is a health science company that provides products used for the prevention, diagnosis and treatment of disease. The company supplies sterilization technologies and medical isotopes to customers in more than 40 countries around the world. - Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes. - Rodents (from Latin "rodere", "to gnaw") are mammals of the order Rodentia, which are characterized by a single pair of continuously growing incisors in each of the upper and lower jaws. About 40% of all mammal species are rodents; they are found in vast numbers on all continents except Antarctica. They are the most diversified mammalian order and live in a variety of terrestrial habitats, including human-made environments. - A radioactive tracer, or radioactive label, is a chemical compound in which one or more atoms have been replaced by a radioisotope so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tracing the path that the radioisotope follows from reactants to products. Radiolabeling is thus the radioactive form of isotopic labeling. - A pet or companion animal is an animal kept primarily for a person's company or protection, as opposed to working animals, sport animals, livestock, and laboratory animals, which are kept primarily for performance, agricultural value, or research. The most popular pets are noted for their attractive appearances and their loyal or playful personalities. - Rats are various medium-sized, long-tailed rodents of the superfamily Muroidea. "True rats" are members of the genus "Rattus", the most important of which to humans are the black rat, "Rattus rattus", and the brown rat, "Rattus norvegicus". Many members of other rodent genera and families are also referred to as rats, and share many characteristics with true rats. - The house mouse ("Mus musculus") is a small mammal of the order Rodentia, characteristically having a pointed snout, small rounded ears, and a long naked or almost hairless tail. It is one of the most numerous species of the genus "Mus". Although a wild animal, the house mouse mainly lives in association with humans. - A mouse (plural: mice) is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate. The best known mouse species is the common house mouse ("Mus musculus"). It is also a popular pet. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. - In immunology, an antigen is a molecule capable of inducing an immune response on the part of the host organism, though sometimes antigens can be part of the host itself. In other words, an antigen is any substance that causes an immune system to produce antibodies against it. Each antibody is specifically produced by the immune system to match an antigen after cells in the immune system come into contact with it; this allows a precise identification of the antigen and the initiation of a tailored response. The antibody is said to "match" the antigen in the sense that it can bind to it thanks to adaptations performed to a region of the antibody; because of this, many different antibodies can be produced, with specificity to bind many different antigens while sharing the same basic structure. In most cases, an antibody can only bind one specific antigen; in some instances, however, antibodies may bind more than one antigen. - Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a single cell lineage). They are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope. - Half-life (abbreviated t) is the time required for a quantity to reduce to half its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo, or how long stable atoms survive, radioactive decay. The term is also used more generally to characterize any type of exponential or non-exponential decay. For example, the medical sciences refer to the biological half-life of drugs and other chemicals in the body. The converse of half-life is doubling time. - Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete large volumes of antibodies. They are transported by the blood plasma and the lymphatic system. Plasma cells originate in the bone marrow; B cells differentiate into plasma cells that produce antibody molecules closely modeled after the receptors of the precursor B cell. Once released into the blood and lymph, these antibody molecules bind to the target antigen (foreign substance) and initiate its neutralization or destruction. - Indium ( 111In ) imciromab ( trade name Myoscint ) is a mouse monoclonal antibody labelled with the radioisotope Indium - 111 . It was used for cardiac imaging , but withdrawn in 1993 . What entity does 'indium ' has the relation 'instance of' with?
A:
chemical compound