You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a scientific passage and an answer, generate a question for the given answer.

Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Why? The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

New input: Passage: Caffeine is an example of a psychoactive drug. It is found in coffee and many other products (see Table below ). Caffeine is a central nervous system stimulant . Like other stimulant drugs, it makes you feel more awake and alert. Other psychoactive drugs include alcohol, nicotine, and marijuana. Each has a different effect on the central nervous system. Alcohol, for example, is a depressant . It has the opposite effects of a stimulant like caffeine. Answer: psychoactive drug
Solution:
What term describes a drug that has an effect on the central nervous system?