instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: The United States Exploring Expedition was an exploring and surveying expedition of the Pacific Ocean and surrounding lands conducted by the United States from 1838 to 1842.
Question: On what date did United States Exploring Expedition end?
answer:
1842

question:
Context: The actions of benzodiazepines are due to the potentiation of the neural inhibition that is mediated by gamma-aminobutyric acid (GABA). Practically all effects of the benzodiazepines result from their actions on the ionotropic GABA(A) receptors in the central nervous system. Benzodiazepines do not activate GABA(A) receptors directly but they require GABA. The main effects of benzodiazepines are sedation, hypnosis, decreased anxiety, anterograde amnesia, centrally mediated muscle relaxation and anti-convulsant activity. In addition to their action on the central nervous system, benzodiazepines have a dose-dependent ventilatory depressant effect and they also cause a modest reduction in arterial blood pressure and an increase in heart rate as a result of a decrease of systemic vascular resistance. The four benzodiazepines, widely used in clinical anaesthesia, are the agonists midazolam, diazepam and lorazepam and the antagonist flumazenil. Midazolam, diazepam and flumazenil are metabolized by cytochrome P450 (CYP) enzymes and by glucuronide conjugation whereas lorazepam directly undergoes glucuronide conjugation. CYP3A4 is important in the biotransformation of both midazolam and diazepam. CYP2C19 is important in the biotransformation of diazepam. Liver and renal dysfunction have only a minor effect on the pharmacokinetics of lorazepam but they slow down the elimination of the other benzodiazepines used in clinical anaesthesia. The duration of action of all benzodiazepines is strongly dependent on the duration of their administration. Based on clinical studies and computer simulations, midazolam has the shortest recovery profile followed by lorazepam and diazepam. Being metabolized by CYP enzymes, midazolam and diazepam have many clinically significant interactions with inhibitors and inducers of CYP3A4 and 2C19. In addition to pharmacokinetic interactions, benzodiazepines have synergistic interactions with other hypnotics and opioids. Midazolam, diazepam and lorazepam are widely used for sedation and to some extent also for induction and maintenance of anaesthesia. Flumazenil is very useful in reversing benzodiazepine-induced sedation as well as to diagnose or treat benzodiazepine overdose.
Question: Which drug should be used as an antidote in benzodiazepine overdose?
answer:
flumazenil

question:
Context: Looking to stop a three-game losing streak, the Raiders welcomed Derek Carr back after missing one week due to injury to face the Los Angeles Chargers. However, things did not start well for Carr as he threw an interception on his first pass of the day and the Chargers took over at the Raider 30-yard line. the defense held the Chargers to a field goal attempt from 48 yards out which was no good. The Raiders took advantage and moved the ball down the field before Carr hit Michael Crabtree from 23 yards out to give the Raiders a 7-0 lead. Neither team could muster much offense until midway through the second quarter when the Chargers moved 82 yards and scored on a Melvin Gordon touchdown run from one yard out to tie the game. With, 1:34 remaining in the half, the Raiders moved into Charger territory and connected on a Giorgio Tavecchio 44-yard field goal as time expired to give the Raiders a 10-7 lead at the half. On their first possession of the second half, the Raiders moved deep into Charger territory, but managed no points as Carr was intercepted for the second time in the game. The teams exchanged punts and fumbles as the game moved into the fourth quarter. The Chargers finally managed some offense as Philip Rivers hit Melvin Gordon for a six-yard touchdown pass to give the Charger at 14-10 lead. On their ensuing possession, Cordarrelle Patterson took the ball on an end around and scampered 47 yards for a touchdown. Giorgio Tavecchio would, however, miss the ensuing point after to leave the Raider lead at two points, 16-14. After exchanging punts, the Chargers took over with 4:09 remaining in the game. Rivers hit Hunter Henry for a 23-yard pass play to move the ball into Raider territory. with less than two minutes remaining, the Chargers moved the ball to the Raider 10 yard line and lined up for the game-winning field goal with three second left in the game. The field goal was good and the Raiders suffered their fourth straight loss, falling to 2-4 on the season. The four losses through six gamed equaled the number of losses they suffered the entire season the prior year. The Raider defense again struggled, giving up 343 total yards while the offense struggled as well, managing only 274 yards. Carr's two interceptions proved costly in his return. After the game, the team said his poor play was not due to his injury.
Question: Which player threw the first TD pass to Crabtree?
answer:
carr