What is the version of the following sentence with correct punctuation?

This is always a controversial issue Factors influencing when to treat the tipping point problematic nodes bulky tumors cosmetic concerns relapse situations transformation Common first treatment choices RBendamustine RCHOP LDIFRT
This is always a controversial issue. Factors influencing when to treat: (the "tipping point", problematic nodes, bulky tumors, cosmetic concerns, relapse situations, transformation. Common first treatment choices: R-Bendamustine, R-CHOP, LDIFRT.