instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Does indoleamine 2,3-dioxygenase inhibition alter the non-coding RNA transcriptome following renal ischemia-reperfusion injury?
Answer: These results suggest a biologic role for non-coding, IDO-dependent genes in regulating the early response to IRI.
answer:
yes

question:
Question: Does apelin-13 protect the heart against ischemia-reperfusion injury through the RISK-GSK-3-mPTP pathway?
Answer: The protective mechanism of apelin-13 might be that inactivation of GSK-3 could inhibit the opening of mPTP by activating PI3K/Akt and ERK1/2 involved in the reperfusion injury salvage kinase (RISK) pathway.
answer:
yes

question:
Question: Is increased risk of breast cancer following irradiation for Hodgkin 's disease a result of ATM germline mutations?
Answer: The data suggest that truncating mutations in the ATM gene are not a major component underlying the increased risk of breast cancer following Hodgkin's disease.
answer:
no