instruction:
In this task, you are given a question and a context passage. You have to answer the question based on the given passage.
question:
What needs to decrease before pituitary growth hormone can increase in the blood?, Context: In addition to the negative consequences of sleep deprivation, sleep and the intertwined circadian system have been shown to have strong regulatory effects on immunological functions affecting both the innate and the adaptive immunity. First, during the early slow-wave-sleep stage, a sudden drop in blood levels of cortisol, epinephrine, and norepinephrine induce increased blood levels of the hormones leptin, pituitary growth hormone, and prolactin. These signals induce a pro-inflammatory state through the production of the pro-inflammatory cytokines interleukin-1, interleukin-12, TNF-alpha and IFN-gamma. These cytokines then stimulate immune functions such as immune cells activation, proliferation, and differentiation. It is during this time that undifferentiated, or less differentiated, like naive and central memory T cells, peak (i.e. during a time of a slowly evolving adaptive immune response). In addition to these effects, the milieu of hormones produced at this time (leptin, pituitary growth hormone, and prolactin) support the interactions between APCs and T-cells, a shift of the Th1/Th2 cytokine balance towards one that supports Th1, an increase in overall Th cell proliferation, and naive T cell migration to lymph nodes. This milieu is also thought to support the formation of long-lasting immune memory through the initiation of Th1 immune responses.
answer:
cortisol, epinephrine, and norepinephrine

question:
What happened earlier, the French invasion in 1672 or Utrecht becoming the centre of the non-Roman Old Catholic Churches in the world?, Context: The fortified city temporarily fell to the French invasion in 1672 (the Disaster Year); where the French invasion was only stopped west of Utrecht at the Old Hollandic Waterline. In 1674, only two years after the French left, the centre of Utrecht was struck by a tornado. The halt to building before construction of flying buttresses in the 15th century now proved to be the undoing of the central section of the cathedral of St Martin church which collapsed; creating the current Dom square between the tower and choir. In 1713, Utrecht hosted one of the first international peace negotiations when the Treaty of Utrecht settled the War of the Spanish Succession. Since 1723 Utrecht became the centre of the non-Roman Old Catholic Churches in the world.
answer:
the French invasion in 1672

question:
what was the last group mentioned?, Context: The Apollo astronauts were chosen from the Project Mercury and Gemini veterans, plus from two later astronaut groups. All missions were commanded by Gemini or Mercury veterans. Crews on all development flights (except the Earth orbit CSM development flights) through the first two landings on Apollo 11 and Apollo 12, included at least two (sometimes three) Gemini veterans. Dr. Harrison Schmitt, a geologist, was the first NASA scientist astronaut to fly in space, and landed on the Moon on the last mission, Apollo 17. Schmitt participated in the lunar geology training of all of the Apollo landing crews.
answer:
Apollo landing crews