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In 1873, one of the first papers in modern medicine on the subject tried to explain the pathophysiology of the disease while one in 1872, concluded that asthma can be cured by rubbing the chest with chloroform liniment. Medical treatment in 1880, included the use of intravenous doses of a drug called pilocarpin. In 1886, F.H. Bosworth theorized a connection between asthma and hay fever. Epinephrine was first referred to in the treatment of asthma in 1905. Oral corticosteroids began to be used for this condition in the 1950s while inhaled corticosteroids and selective short acting beta agonist came into wide use in the 1960s.

When was the first paper written about asthma?
Answer: In 1873
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It was temporarily under the control of the Tibetan empire and Chinese from 650680 and then under the control of the Umayyads in 710. The Samanid Empire, 819 to 999, restored Persian control of the region and enlarged the cities of Samarkand and Bukhara (both cities are today part of Uzbekistan) which became the cultural centers of Iran and the region was known as Khorasan. The Kara-Khanid Khanate conquered Transoxania (which corresponds approximately with modern-day Uzbekistan, Tajikistan, southern Kyrgyzstan and southwest Kazakhstan) and ruled between 9991211. Their arrival in Transoxania signaled a definitive shift from Iranian to Turkic predominance in Central Asia, but gradually the Kara-khanids became assimilated into the Perso-Arab Muslim culture of the region.

Who conquered Tansaxania?
Answer: The Kara-Khanid Khanate
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Many Indo-Aryan languages have aspirated stops. Sanskrit, Hindi, Bengali, Marathi, and Gujarati have a four-way distinction in stops: voiceless, aspirated, voiced, and breathy-voiced or voiced aspirated, such as /p p b b/. Punjabi has lost breathy-voiced consonants, which resulted in a tone system, and therefore has a distinction between voiceless, aspirated, and voiced: /p p b/.

Which distinction has Punjabi lost?
Answer:
breathy-voiced consonants