Given a scientific passage and an answer, generate a question for the given answer.
Example: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Example solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Example explanation: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

Problem: Passage: The mechanical advantage of a simple machine such as a pulley is the factor by which the machine changes the force applied to it. The ideal mechanical advantage of a machine is its mechanical advantage in the absence of friction. All machines must overcome friction, so the ideal mechanical advantage is always somewhat greater than the actual mechanical advantage of the machine as it is used in the real world. Answer: friction
Solution: What is something that all machines must overcome?