QUES: Exposure to antibiotics early in life is associated with increased body mass in humans and mouse models. Early life is a critical period for the establishment of the intestinal microbiota and for metabolic development. Mice exposed to subtherapeutic antibiotic treatment (STAT) with either penicillin, vancomycin, penicillin and vancomycin, or chlortetracycline had altered composition of the gut microbiota as well as its metabolic capabilities. Moreover, research have shown that mice given low-dose penicillin (1 g/g body weight) around birth and throughout the weaning process had an increased body mass and fat mass, accelerated growth, and increased hepatic expression of genes involved in adipogenesis, compared to controlled mice. In addition, penicillin in combination with a high-fat diet increased fasting insulin levels in mice. However, it is unclear whether or not antibiotics cause obesity in humans. Studies have found a correlation between early exposure of antibiotics (<6 months) and increased body mass (at 10 and 20 months). Another study found that the type of antibiotic exposure was also significant with the highest risk of being overweight in those given macrolides compared to penicillin and cephalosporin. Therefore, there is correlation between antibiotic exposure in early life and obesity in humans, but whether or not there is a causal relationship remains unclear. Although there is a correlation between antibiotic use in early life and obesity, the effect of antibiotics on obesity in humans needs to be weighed against the beneficial effects of clinically indicated treatment with antibiotics in infancy.

What are some antibiotics can be used for STAT?
What is the answer?
ANS: penicillin, vancomycin, penicillin and vancomycin, or chlortetracycline
QUES: The rule of law is the legal principle that law should govern a nation, as opposed to being governed by arbitrary decisions of individual government officials. It primarily refers to the influence and authority of law within society, particularly as a constraint upon behaviour, including behaviour of government officials. The phrase can be traced back to 16th century Britain, and in the following century the Scottish theologian Samuel Rutherford used the phrase in his argument against the divine right of kings. The rule of law was further popularized in the 19th century by British jurist A. V. Dicey. The concept, if not the phrase, was familiar to ancient philosophers such as Aristotle, who wrote "Law should govern".

What country can a phrase rule of law be traced back to the 1600s?
What is the answer?
ANS: unanswerable
QUES: To promote culture Utrecht city organizes cultural Sundays. During a thematic Sunday several organisations create a program, which is open to everyone without, or with a very much reduced, admission fee. There are also initiatives for amateur artists. The city subsidises an organisation for amateur education in arts aimed at all inhabitants (Utrechts Centrum voor de Kunsten), as does the university for its staff and students. Additionally there are also several private initiatives. The city council provides coupons for discounts to inhabitants who receive welfare to be used with many of the initiatives.

What does the city host on Sundays
What is the answer?
ANS:
To promote culture Utrecht city organizes cultural Sundays