You will be given a definition of a task first, then some input of the task.
In this task, you're given a statement and three sentences as choices. Your job is to determine which sentence can be inferred from the statement. Incorrect choices change the meaning in important ways or have details that are not mentioned in the statement. Indicate your answer as 1,2, or 3 corresponding to the choice number of the selected sentence.

Statement: The city has a long-standing international reputation for research and development, which began in 1681 with the founding of the Royal College of Physicians. Choices: 1. Research and development is a long tradition in the city, going back to 1681. 2. The city is the most popular place for research and development. 3. The city is not known for its research quality.
Output:
1