Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Are polymorphisms in SPINK5 associated with asthma in a Dutch population?
Answer: The negative results in this study suggest that SPINK5 is not associated with asthma or atopic phenotypes in individuals ascertained by a proband with asthma. This is consistent with the finding that SPINK5 is not expressed in the lung. Because our patients were ascertained for asthma, a role of SPINK5 in atopic dermatitis cannot be excluded.

Answer: no

Question: Question: Is cytosine deamination a major cause of baseline noise in next-generation sequencing?
Answer: Baseline noise during NGS is mostly due to cytosine deamination, the source of which is likely to be both biologic and an artifact of thermocycling, and it can be reduced by UNG pretreatment.

Answer: yes

Question: Question: Does mRI-based ACL graft maturity predict clinical and functional outcomes during the first year after ACL reconstruction?
Answer: The MRI-based graft maturity does not have the ability to predict clinical and functional outcomes in patients at the first-year follow-up. Graft maturity should not be used as an objective test to determine the appropriate time to return to sports during the first year after ACL reconstruction. The results from this study will allow clinicians to determine graft-specific health to determine whether the graft is healed enough to return to sports during the first postoperative year.

Answer:
no