Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
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Question: Context: Private investigator Patrick Kenzie (Casey Affleck) and his partner/girlfriend Angie Gennaro (Michelle Monaghan) witness a televised plea by a woman named Helene McCready (Amy Ryan) for the return of her missing daughter Amanda, who was abducted with her favorite doll "Mirabelle". Patrick and Angie are then hired by the child's aunt Beatrice (Amy Madigan) to find Amanda and discover that Helene and her boyfriend "Skinny Ray" (Sean Malone) had recently stolen money from Cheese (Edi Gathegi), a local Haitian drug lord. After Ray is murdered, Patrick and Angie join the police detectives Remy Bressant (Ed Harris) and Nick Poole (John Ashton) with investigating the case and assist in arranging the trade of money for the return of Amanda. Captain Jack Doyle (Morgan Freeman) reads Patrick a telephone transcript of the drug lord setting up an exchange for Amanda. The exchange at a nearby quarry in Quincy is botched and it is believed Amanda drowned; her doll is found in the quarry and returned to Helene. Doyle, whose own daughter was killed years before, takes responsibility for the death and goes into early retirement. Two months later, a seven year old boy is abducted in Everett and Patrick receives information that the boy was taken by a known child molester. After entering the suspect's house and finding evidence of the abducted boy, Patrick returns with Remy and Nick to rescue him. They are seen by the residents and Nick is shot. Patrick enters the house during the shootout and finds one of the residents dead. He retreats into the child molester's room, where he finds the boy's dead body; he then shoots the child molester in the back of the head in a fit of rage. Nick later dies of his wounds. Trying to alleviate Patrick's guilt over the events at the house, Remy unthinkingly confides that he once planted evidence on someone with the help of "Skinny Ray" whom he had initially told Patrick he didn't know. After Nick's funeral, Patrick speaks to a police officer, who tells him that Remy had been asking about the drug lord's stolen money before the drug lord knew it was missing. Patrick then questions Beatrice's husband Lionel (Titus Welliver) in a bar and pieces together that Lionel and Remy had conspired to stage a fake kidnapping in order to take the drug money for themselves and to take Amanda from her neglectful mother's care. At that point, Remy (trying to cover for his earlier mistake) enters the bar, while wearing a latex mask and holding a shotgun, and stages a robbery. He points the shotgun at Lionel's head, but the bartender shoots Remy twice in the back. Remy flees and is pursued by Patrick to the rooftop of a nearby building, where he dies. Patrick is questioned by the police about Remy's death and learns that the police never had a phone transcript like the one that Doyle had read to him prior to the botched exchange. Patrick and Angie drive to Doyle's home, where Patrick finds Amanda living with Doyle and his wife; Doyle was part of the phony kidnapping all along. Patrick threatens to call the authorities, but Doyle attempts to convince him that Amanda is better off living with them than with her mother, and that is reason enough not to get involved. Patrick leaves and discusses the choices with Angie, who says she will leave him if he calls the police, since she also believes Amanda is much better off with the Doyles. In the next scene, the police arrive, Doyle is arrested, Amanda is returned to her mother amidst heavy publicity, and Patrick and Angie break up. Patrick later visits Amanda as Helene is about to leave on a date with someone she met during the publicity over her daughter's disappearance. Helene informs Patrick that Beatrice has been forbidden to visit and is upset about her husband's arrest. Helene has no babysitter for Amanda and when asked, she tells Patrick that Helene's friend, Dottie (Jill Quigg) will watch her, even though she has yet to ask Dottie herself. Patrick volunteers to watch Amanda, who is holding her
Question: What weapon did Remy stage a robbery with?

Answer: shotgun

Question: Context: Chronic myeloid leukemia (CML) is genetically characterized by the presence of the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR/ABL gene fusion on the derivative chromosome 22 called the Philadelphia (Ph) chromosome. In 2-10% of the cases, this chimeric gene is generated by variant rearrangements, involving 9q34, 22q11, and one or several other genomic regions. All chromosomes have been described as participating in these variants, but there is a marked breakpoint clustering to chromosome bands 1p36, 3p21, 5q13, 6p21, 9q22, 11q13, 12p13, 17p13, 17q21, 17q25, 19q13, 21q22, 22q12, and 22q13. Despite their genetically complex nature, available data indicate that variant rearrangements do not confer any specific phenotypic or prognostic impact as compared to CML with a standard Ph chromosome. In most instances, the t(9;22), or a variant thereof, is the sole chromosomal anomaly during the chronic phase (CP) of the disease, whereas additional genetic changes are demonstrable in 60-80% of cases in blast crisis (BC). The secondary chromosomal aberrations are clearly nonrandom, with the most common chromosomal abnormalities being +8 (34% of cases with additional changes), +Ph (30%), i(17q) (20%), +19 (13%), -Y (8% of males), +21 (7%), +17 (5%), and monosomy 7 (5%). We suggest that all these aberrations, occurring in >5% of CML with secondary changes, should be denoted major route abnormalities. Chromosome segments often involved in structural rearrangements include 1q, 3q21, 3q26, 7p, 9p, 11q23, 12p13, 13q11-14, 17p11, 17q10, 21q22, and 22q10. No clear-cut differences as regards type and prevalence of additional aberrations seem to exist between CML with standard t(9;22) and CML with variants, except for slightly lower frequencies of the most common changes in the latter group. The temporal order of the secondary changes varies, but the preferred pathway appears to start with i(17q), followed by +8 and +Ph, and then +19. Molecular genetic abnormalities preceding, or occurring during, BC include overexpression of the BCR/ABL transcript, upregulation of the EVI1 gene, increased telomerase activity, and mutations of the tumor suppressor genes RB1, TP53, and CDKN2A. The cytogenetic evolution patterns vary significantly in relation to treatment given during CP. For example, +8 is more common after busulfan than hydroxyurea therapy, and the secondary changes seen after interferon-alpha treatment or bone marrow transplantation are often unusual, seemingly random, and occasionally transient. Apart from the strong phenotypic impact of addition of acute myeloid leukemia/myelodysplasia-associated translocations and inversions, such as inv(3)(q21q26), t(3;21)(q26;q22), and t(15;17)(q22;q12-21), in CML BC, only a few significant differences between myeloid and lymphoid BC are discerned, with i(17q) and TP53 mutations being more common in myeloid BC and monosomy 7, hypodiploidy, and CDKN2A deletions being more frequent in lymphoid BC. The prognostic significance of the secondary genetic changes is not uniform, although abnormalities involving chromosome 17, e.g., i(17q), have repeatedly been shown to be ominous. However, the clinical impact of additional cytogenetic and molecular genetic aberrations is most likely modified by the treatment modalities used.
Question: Which gene fusion is the result of the "philadelphia translocation" or the "philadelphia chromosome" mutation?

Answer: the bcr/abl gene fusion

Question: Context: Methicillin-resistant Staphylococcus aureus (MRSA) is an increasing problem. Rapid detection of MRSA-colonized patients has the potential to limit spread of the organism. We evaluated the sensitivities and specificities of MRSA detection by two molecular methods (IDI-MRSA PCR assay and GenoType MRSA Direct PCR assay) and three selective MRSA agars (MRSA ID, MRSASelect, and CHROMagar MRSA), using 205 (101 nasal, 52 groin, and 52 axillary samples) samples from consecutive known MRSA-infected and/or -colonized patients. All detection methods had higher MRSA detection rates for nasal swabs than for axillary and groin swabs. Detection of MRSA by IDI-MRSA was the most sensitive method, independent of the site (94% for nasal samples, 80% for nonnasal samples, and 90% overall). The sensitivities of the GenoType MRSA Direct assay and the MRSA ID, MRSASelect, and CHROMagar MRSA agars with nasal swabs were 70%, 72%, 68%, and 75%, respectively. All detection methods had high specificities (95 to 99%), independent of the swab site. Extended incubation for a further 24 h with selective MRSA agars increased the detection of MRSA, with a corresponding decline in specificity secondary to a significant increase in false-positive results. There was a noticeable difference in test performance of the GenoType MRSA Direct assay in detection of MRSA (28/38 samples [74%]) compared with detection of nonmultiresistant MRSA (17/31 samples [55%]) (susceptible to two or more non-beta-lactam antibiotics). This was not observed with selective MRSA agar plates or IDI-MRSA. Although it is more expensive, in addition to rapid turnaround times of 2 to 4 h, IDI-MRSA offers greater detection of MRSA colonization, independent of the swab site, than do conventional selective agars and GenoType MRSA Direct.
Question: What is MRSA?

Answer:
mrsa