Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does single copy of variant CYP2A6 alleles confer susceptibility to liver dysfunction in patients treated with coumarin?
Answer: No evidence was obtained that the studied polymorphism in CYP2A6 is a determinant of the coumarin-associated liver dysfunction.

Answer: no

Question: Question: Does the methionine-choline deficient dietary model of steatohepatitis exhibit insulin resistance?
Answer: GTT, ITT and QUICKI confirmed the absence of insulin resistance in the MCD fed mice. This model causes fibrosing steatohepatitis and may help delineate the non-insulin resistant mechanisms involved in human steatohepatitis.

Answer: no

Question: Question: Does conventional carbon dioxide application reduce cerebral or myocardial damage in open heart surgery?
Answer: Although mortality was lower with CO2 insufflation, no benefit could be demonstrated for markers of cardiac ischemic damage or neurocognitive outcome in this high-risk population. As CO2 concentrations in the thoracic cavity did not necessarily reach anticipated levels, our method of application is in question.

Answer:
no