Teacher:In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Teacher: Now, understand the problem? Solve this instance: Question: The development of generic drugs is based on the evaluation of the bioequivalence of the generic compared to a reference product already marketed. This concept refers to:
Options: <1> The evaluation of equivalence in clinical efficacy trials. <2> The assessment of similarity in clinical trials of tolerance. <3> The equivalence in the distribution process of a drug and, therefore, to the verification that it has the same concentrations in the place of action. <4> The evaluation of pharmacokinetic equivalence. <5> The verification of a similar effect of the factors that influence the bioavailability of a drug.
Student:
4