Part 1. Definition
In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Part 2. Example
The severe acute respiratory syndrome (SARS) epidemic originating from China in 2002 was caused by a previously uncharacterized coronavirus that could be identified by specific RT-PCR amplification. Efforts to control future SARS outbreaks depend on the accurate and early identification of SARS-CoV infected patients. A real-time fluorogenic RT-PCR assay based on the 3 -noncoding region (3 -NCR) of SARS-CoV genome was developed as a quantitative SARS diagnostic tool. The ideal amplification efficiency of a sensitive SARS-CoV RT-PCR assay should yield an E value (PCR product concentration increase per amplification cycle) equal to 2.0. It was demonstrated that the 3 -NCR SARS-CoV based RT-PCR reactions could be formulated to reach excellent E values of 1.81, or 91% amplification efficacy. The SARS-CoV cDNA preparations derived from viral RNA extract and the cloned recombinant plasmid both exhibit the identical amplification characteristics, i.e. amplification efficacy using the same PCR formulation developed in this study. The viral genomic copy (or genomic equivalences, GE) per infectious unit (GE/pfu) of SARS-CoV used in this study was also established to be approximate 1200-1600:1. The assay's detection sensitivity could reach 0.005 pfu or 6-8 GE per assay. It was preliminarily demonstrated that the assay could efficiently detect SARS-CoV from clinical specimens of SARS probable and suspected patients identified in Taiwan. The 3 -NCR based SARS-CoV assay demonstrated 100% diagnostic specificity testing samples of patients with acute respiratory disease from a non-SARS epidemic region.
Answer: Development and evaluation of an efficient 3 -noncoding region-based SARS coronavirus (SARS-CoV) RT-PCR assay for detection of SARS-CoV
Explanation: It's a correct title because the paragraph described the development of 3 -noncoding region of SARS-CoV genome and assay efficiently detecting SARS-CoV from clinical specimens.
Part 3. Exercise
Objective. In treating highly infectious COVID-19 pneumonia, ICU nurses face a high 34 risk of developing somatic symptom disorder (SSD). The present study aims to investigate 35 the symptoms and causes of SSD of ICU nurses treating COVID-19 pneumonia. The research 36 results are expected to provide evidence for the establishment of a better management 37 strategy. Methods. This study enrolled a total of 140 ICU nurses who were selected by Jiangsu 39 Province Hospital to work in Wuhan (the epicenter of the COVID-19 epidemic in China) on 40 3 rd February 2020. A questionnaire "Somatic Symptom Disorders for ICU Nurses in Wuhan 41 No.1 Hospital" was designed based on the "International Classification of Functioning, 42 Disability and Health" (ICF). Exploratory factor analysis was performed to cluster the 43 symptoms, and logistic regression analysis to find the risk factors of the symptoms. 44 Results. Five major symptoms were chest-discomfort-and-palpitation (31.4%), dyspnea 45 (30.7%), nausea (21.4%), headache (19.3%), and dizziness (17.9%). In exploratory factor 46 analysis, the symptoms were classified into three clusters: Cluster A of breathing and sleep 47 disturbances (dizziness, sleepiness, dyspnea); Cluster B of gastrointestinal complaints and 48 pain (nausea, headache), and Cluster C of general symptoms (xerostomia, fatigue, 49 chest-discomfort-and-palpitation). In Cluster A, urine/feces splash, sex, and sputum splash 50 were independent predictive factors. In Cluster B, fall of protective glasses and urine/feces 51 splash were independent predictive factors. In Cluster C, urine/feces splash and urine/feces 52 clearance were independent predictive factors. 53 Conclusion. The ICU nurses in Wuhan showed varying and overlapping SSDs. These 54 SSDs could be classified into three symptom clusters. Based on the characteristics of their 55 SSDs, specific interventions could be implemented to safeguard the health of ICU nurses. 56 57
Answer:
Journal Pre-proof Symptom Cluster of ICU nurses treating COVID-19 pneumonia patients in Wuhan, China Running Title: SSDs of ICU nurses treating COVID-19 pneumonia patients Symptom Cluster of ICU nurses treating COVID-19 pneumonia patients in Wuhan, China Somatic Symptom Disorders of ICU Nurses treating COVID-19 pneumonia patients in