TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: The Chiefs took an early lead on a 30-yard pass from Tyler Thigpen to Mark Bradley. The Chiefs defense continued to show improvement in the red zone, limiting the Chargers to two field goals instead of two touch downs. At the end of the first half, Thigpen threw a pass to 34yard touchdown pass to Tony Gonzalez. However, the extra point snap was botched and an attempt at a quick pass failed. The Chargers controlled the second half better than the first, scoring two touchdowns and leading the Chiefs by 7 at the end of the fourth quarter. The Chiefs' final drive ended with a 3-yard touchdown pass to Gonzalez. A 1-point PAT would tie the game. However, Herm Edwards told Thigpen to go for two, explaining in a post-game interview that the defense was too beat up for overtime play. The resulting two-point conversion ended in an incomplete pass. The Chiefs lost by one point.

SOLUTION: Which team won the game?

PROBLEM: Phosphorylation of cytoplasmic polyadenylation element binding protein (CPEB) regulates protein synthesis in hippocampal dendrites. CPEB binds the 3' untranslated region (UTR) of cytoplasmic mRNAs and, when phosphorylated, initiates mRNA polyadenylation and translation. We report that, of the protein kinases activated in the hippocampus during synaptic plasticity, calcium/calmodulin-dependent protein kinase II (CaMKII) robustly phosphorylated the regulatory site (threonine 171) in CPEB in vitro. In postsynaptic density fractions or hippocampal neurons, CPEB phosphorylation increased when CaMKII was activated. These increases in CPEB phosphorylation were attenuated by a specific peptide inhibitor of CaMKII and by the general CaM-kinase inhibitor KN-93. Inhibitors of protein phosphatase 1 increased basal CPEB phosphorylation in neurons; this was also attenuated by a CaM-kinase inhibitor. To determine whether CaM-kinase activity regulates CPEB-dependent mRNA translation, hippocampal neurons were transfected with luciferase fused to a 3' UTR containing CPE-binding elements. Depolarization of neurons stimulated synthesis of luciferase; this was abrogated by inhibitors of protein synthesis, mRNA polyadenylation, and CaMKII. These results demonstrate that CPEB phosphorylation and translation are regulated by CaMKII activity and provide a possible mechanism for how dendritic protein synthesis in the hippocampus may be stimulated during synaptic plasticity.

SOLUTION: Which kinase is inhibited by the small molecule KN-93?

PROBLEM: Sami Mubarak Faraj Ba Owain commonly known as Sami Mubarak (Arabic: ; born 12 November 1991) is an Omani footballer who plays for Dhofar S.C.S.C. in the Oman Professional League.

SOLUTION:
Which sports team is Sami Mubarak a member of?