Input: Article: The boroughs are composed by hundreds of colonias or neighborhoods, which have no jurisdictional autonomy or representation. The Historic Center is the oldest part of the city (along with some other, formerly separate colonial towns such as Coyoacan and San Angel), some of the buildings dating back to the 16th century. Other well-known central neighborhoods include Condesa, known for its Art Deco architecture and its restaurant scene; Colonia Roma, a beaux arts neighborhood and artistic and culinary hot-spot, the Zona Rosa, formerly the center of nightlife and restaurants, now reborn as the center of the LGBT and Korean-Mexican communities; and Tepito and La Lagunilla, known for their local working-class foklore and large flea markets. Santa Maria la Ribera and San Rafael are the latest neighborhoods of magnificent Porfiriato architecture seeing the first signs of gentrification.

Now answer this question: What is the oldest part of the city?

Output: The Historic Center

Input: Article: By far the largest military action in which the United States engaged during this era was the War of 1812. With Britain locked in a major war with Napoleon's France, its policy was to block American shipments to France. The United States sought to remain neutral while pursuing overseas trade. Britain cut the trade and impressed seamen on American ships into the Royal Navy, despite intense protests. Britain supported an Indian insurrection in the American Midwest, with the goal of creating an Indian state there that would block American expansion. The United States finally declared war on the United Kingdom in 1812, the first time the U.S. had officially declared war. Not hopeful of defeating the Royal Navy, the U.S. attacked the British Empire by invading British Canada, hoping to use captured territory as a bargaining chip. The invasion of Canada was a debacle, though concurrent wars with Native Americans on the western front (Tecumseh's War and the Creek War) were more successful. After defeating Napoleon in 1814, Britain sent large veteran armies to invade New York, raid Washington and capture the key control of the Mississippi River at New Orleans. The New York invasion was a fiasco after the much larger British army retreated to Canada. The raiders succeeded in the burning of Washington on 25 August 1814, but were repulsed in their Chesapeake Bay Campaign at the Battle of Baltimore and the British commander killed. The major invasion in Louisiana was stopped by a one-sided military battle that killed the top three British generals and thousands of soldiers. The winners were the commanding general of the Battle of New Orleans, Major General Andrew Jackson, who became president and the Americans who basked in a victory over a much more powerful nation. The peace treaty proved successful, and the U.S. and Britain never again went to war. The losers were the Indians, who never gained the independent territory in the Midwest promised by Britain.

Now answer this question: What was the initial US strategy in the War of 1812?

Output: invading British Canada, hoping to use captured territory as a bargaining chip

Input: Article: Often, large multinational corporations exhibit vertical integration, participating in a broad range of drug discovery and development, manufacturing and quality control, marketing, sales, and distribution. Smaller organizations, on the other hand, often focus on a specific aspect such as discovering drug candidates or developing formulations. Often, collaborative agreements between research organizations and large pharmaceutical companies are formed to explore the potential of new drug substances. More recently, multi-nationals are increasingly relying on contract research organizations to manage drug development.

Now answer this question: What type of agreements are made to research potential new drugs?

Output:
collaborative agreements