Given the task definition and input, reply with output. Given a passage and a query based on the passage, generate an unambiguous, concise and simple answer to the query from information in the passage. Note that the answer may not be present in exact form.

Valium Long-Term Effects. Heavy use of Valium over an extended period of time can have powerful effects on the brain and body. These effects can be permanent and, in some cases, life-threatening. The long-term effects of Valium include: Memory loss. Hallucinations. Difficulty breathing. Slowed pulse. Coma. Heart attack. The half-life of Valium is fairly long it can take 20 hours or more for just half of the medication to be eliminated from your system. However, just because it's not completely eliminated after 20 hours doesn't mean it's still effective. Valium Long-Term Effects Heavy use of Valium over an extended period of time can have powerful effects on the brain and body. These effects can be permanent and, in some cases, life-threatening. So you would actually have to account for the elimination of N-desmethyldiazepam. It takes 5.5 x elimination half lives (hours) for a medicine to be cleared from your system, therefore Valium or it's active metabolite will be in your system for 550 hours (5.5 x 100hrs) i.e. approximately 23 days. Both temazepam and oxazepam have a modest half-life of 8-9 hours. Due to the long half-life of diazepam it works for a significant period of time. Most of the effects last about 6-8 hours, after that time Valium and its active metabolites continue to exert very subtle and very mild effects that are often unnoticed. Valium affects the levels of gamma-aminobutyric acid (GABA) in the brain, helping to slow down and stop abnormal brain activity. This results in a calming effect, and sometimes feelings of euphoria. It helps reduce anxiety, cause sleepiness, relax muscles, stop seizures, and more. Depends on the strength. A 10mg will kick in around 30 to 60 minutes after ingesting and last about 4-6 hrs. It stays in your system for over 100+ hours, although the effects are gone after 6 hrs. It really took the edge off my fear (40 min in the machine) but there is not easy way to tell when it actually wears off. about 2 hours after i took it a had a nap which turned out to be a pretty deep 2 hour affair :-) when i got up i would say for sure there was nothing left of the Valium... How long a drug stays in your system depends mainly on it's elimination half life. For Valium (diazepam) the initial distribution phase is followed by a prolonged terminal elimination phase (half-life up to 48 hours). The terminal elimination half-life of the active metabolite N-desmethyldiazepam is, on average, 100 hours. Side Effects. When used properly, Valium does not produce the same effects as it does when abused/misused. Valium has side effects with proper use, but these are temporary and should go away after a few standard doses. The Dangers of Valium For 13 years, Valium was the most prescribed drug in America. Query: how long do effects of valium last in the body
Most of the effects last about 6-8 hours, after that time Valium.