In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Q: These data suggest that the IL - 2 and CD3 signaling pathways provide a necessary and co - operative stimulus promoting phosphorylation of CREB following receptor cross - linking .

A: IL - 2
****
Q: Using the specific pharmacological inhibitors of PI 3 - kinase , Wortmannin and LY294002 , we demonstrate that PI 3 - kinase activity is vital for BCR - induced NF - kappaB DNA - binding activity .

A: NF - kappaB
****
Q: The growth inhibition caused by Mad1 is overcome by expression of active c - Myc .

A:
c - Myc
****