Problem: Background: Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. Paragraph: Two university students studied different types of drugs for their exams. Kate studied statins, while Carol studied anti-depressants. Given the paragraph above, please answer correctly the following question: Which student learned more about an inhibitor of HMG-CoA reductase?

A: Kate

Problem: Background: Saturated hydrocarbons are given the general name of alkanes . The name of specific alkanes always ends in - ane . The first part of the name indicates how many carbon atoms each molecule of the alkane has. The smallest alkane is methane. It has just one carbon atom. The next largest is ethane, with two carbon atoms. The chemical formulas and properties of methane, ethane, and several other alkanes are listed in Table below . The boiling and melting points of alkanes are determined mainly by the number of carbon atoms they have. Alkanes with more carbon atoms generally have higher boiling and melting points. Paragraph: Vic and Joe studied chemistry in school. Joe studied alkanes, while his friend Vic studied other acyclic hydrocarbons. Given the paragraph above, please answer correctly the following question: Which friend studied less about ethane gas?

A: Joe

Problem: Background: The Laffer curve depicts the amount of government revenue as a function of the rate of taxation. It shows that for a tax rate above a certain critical rate, government revenue starts decreasing as the tax rate rises, as a consequence of a decline in labour supply. This theory supports that, if the tax rate is above that critical point, a decrease in the tax rate should imply a rise in labour supply that in turn would lead to an increase in government revenue. Paragraph: The country of Hinland reduced taxation hoping it would mean more money for government spending. On the other hand, Silvania, a southern country increased taxation hoping they would increase collection amounts. The problem was that Silvanian people increased taxation above the critical rate. Given the paragraph above, please answer correctly the following question: Which country increased their taxes?

A: Silvania

Problem: Background: The trade-off theory of capital structure is the idea that a company chooses how much debt finance and how much equity finance to use by balancing the costs and benefits. The classical version of the hypothesis goes back to Kraus and Litzenberger[1] who considered a balance between the dead-weight costs of bankruptcy and the tax saving benefits of debt. Often agency costs are also included in the balance. This theory is often set up as a competitor theory to the pecking order theory of capital structure. A review of the literature is provided by Frank and Goyal.[2] An important purpose of the theory is to explain the fact that corporations usually are financed partly with debt and partly with equity. It states that there is an advantage to financing with debt, the tax benefits of debt and there is a cost of financing with debt, the costs of financial distress including bankruptcy costs of debt and non-bankruptcy costs (e.g. staff leaving, suppliers demanding disadvantageous payment terms, bondholder/stockholder infighting, etc.). The marginal benefit of further increases in debt declines as debt increases, while the marginal cost increases, so that a firm that is optimizing its overall value will focus on this trade-off when choosing how much debt and equity to use for financing. Paragraph: Company X stopped taking on more debt, and decided to file for bankruptcy, while company Y, kept benefiting from the tax benefits of debt, having a lower debt level. Given the paragraph above, please answer correctly the following question: Which company had less problems with stockholders fighting, company X or company Y?

A:
company Y