In this task, you are given a part of an article. Your task is to generate headline (title) for this text. Preferred headlines are under fifteen words.

Input: Consider Input: Proposed methods for prediction interval estimation so far focus on cases where input variables are numerical. In datasets with solely nominal input variables, we observe records with the exact same input x, but different real valued outputs due to the inherent noise in the system. Existing prediction interval estimation methods do not use representations that can accurately model such inherent noise in the case of nominal inputs. We propose a new prediction interval estimation method tailored for this type of data, which is prevalent in biology and medicine. We call this method Distribution Adaptive Prediction Interval Estimation given Nominal inputs (DAPIEN) and has four main phases. First, we select a distribution function that can best represent the inherent noise of the system for all unique inputs. Then we infer the parameters i (e.g. i = [meani, variancei]) of the selected distribution function for all unique input vectors xi and generate a new corresponding training set using pairs of xi , i. III). Then, we train a model to predict given a new xu. Finally, we calculate the prediction interval for a new sample using the inverse of the cumulative distribution function once the parameters is predicted by the trained model. We compared DAPIEN to the commonly used Bootstrap method on three synthetic datasets. Our results show that DAPIEN provides tighter prediction intervals while preserving the requested coverage when compared to Bootstrap. This work can facilitate broader usage of regression methods in medicine and biology where it is necessary to provide tight prediction intervals while preserving coverage when input variables are nominal.

Output: DICTION INTERVAL ESTIMATION USING NOMINAL VARIABLES

Input: Consider Input: Dependency parsers are among the most crucial tools in natural language processing as they have many important applications in downstream tasks such as information retrieval, machine translation and knowledge acquisition. We introduce the Yara Parser, a fast and accurate open-source dependency parser based on the arc-eager algorithm and beam search. It achieves an unlabeled accuracy of 93.32 on the standard WSJ test set which ranks it among the top dependency parsers. At its fastest, Yara can parse about 4000 sentences per second when in greedy mode (1 beam). When optimizing for accuracy (using 64 beams and Brown cluster features), Yara can parse 45 sentences per second. The parser can be trained on any syntactic dependency treebank and different options are provided in order to make it more flexible and tunable for specific tasks. It is released with the Apache version 2.0 license and can be used for both commercial and academic purposes. The parser can be found at https: //github.com/yahoo/YaraParser.

Output: Yara Parser: A Fast and Accurate Dependency Parser

Input: Consider Input: This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties. We demonstrate how this model can execute a range of tasks such as generating analogues to a query structure and generating compounds predicted to be active against a biological target. As a proof of principle, the model is first trained to generate molecules that do not contain sulphur. As a second example, the model is trained to generate analogues to the drug Celecoxib, a technique that could be used for scaffold hopping or library expansion starting from a single molecule. Finally, when tuning the model towards generating compounds predicted to be active against the dopamine receptor D2, the model generates structures of which more than 95% are predicted to be active, including experimentally confirmed actives that have not been included in either the generative model nor the activity prediction model.
Output: Molecular De-Novo Design through Deep Reinforcement Learning