In the mid-1950s, Frank Burnet, inspired by a suggestion made by Niels Jerne, formulated the clonal selection theory (CST) of immunity. On the basis of CST, Burnet developed a theory of how an immune response is triggered according to the self/nonself distinction: "self" constituents (constituents of the body) do not trigger destructive immune responses, while "nonself" entities (e.g., pathogens, an allograft) trigger a destructive immune response. The theory was later modified to reflect new discoveries regarding histocompatibility or the complex "two-signal" activation of T cells. The self/nonself theory of immunity and the self/nonself vocabulary have been criticized, but remain very influential.
What medical scientist first proposed the clonal selection theory of immunology?
Frank Burnet

Historically, pubs have been socially and culturally distinct from cafes, bars and German beer halls. Most pubs offer a range of beers, wines, spirits, and soft drinks and snacks. Traditionally the windows of town pubs were of smoked or frosted glass to obscure the clientele from the street but from the 1990s onwards, there has been a move towards clear glass, in keeping with brighter interiors.
What are traditional pub windows made out of?
smoked or frosted glass

With an estimated population of 1,381,069 as of July 1, 2014, San Diego is the eighth-largest city in the United States and second-largest in California. It is part of the San DiegoTijuana conurbation, the second-largest transborder agglomeration between the US and a bordering country after DetroitWindsor, with a population of 4,922,723 people. San Diego is the birthplace of California and is known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the United States Navy and recent emergence as a healthcare and biotechnology development center.
Aside from healthcare, which employment sector has strongly emerged in San Diego?
biotechnology development