Input: Time
Time appears to have a directionthe past lies behind, fixed and immutable, while the future lies ahead and is not necessarily fixed. Yet for the most part the laws of physics do not specify an arrow of time, and allow any process to proceed both forward and in reverse. This is generally a consequence of time being modeled by a parameter in the system being analyzed, where there is no "proper time": the direction of the arrow of time is sometimes arbitrary. Examples of this include the Second law of thermodynamics, which states that entropy must increase over time (see Entropy); the cosmological arrow of time, which points away from the Big Bang, CPT symmetry, and the radiative arrow of time, caused by light only traveling forwards in time (see light cone). In particle physics, the violation of CP symmetry implies that there should be a small counterbalancing time asymmetry to preserve CPT symmetry as stated above. The standard description of measurement in quantum mechanics is also time asymmetric (see Measurement in quantum mechanics).

The direction of the arrow of time is sometimes what?
Output: arbitrary

Input: Nutrition
The conversion rate of omega-6 DGLA to AA largely determines the production of the prostaglandins PGE1 and PGE2. Omega-3 EPA prevents AA from being released from membranes, thereby skewing prostaglandin balance away from pro-inflammatory PGE2 (made from AA) toward anti-inflammatory PGE1 (made from DGLA). Moreover, the conversion (desaturation) of DGLA to AA is controlled by the enzyme delta-5-desaturase, which in turn is controlled by hormones such as insulin (up-regulation) and glucagon (down-regulation). The amount and type of carbohydrates consumed, along with some types of amino acid, can influence processes involving insulin, glucagon, and other hormones; therefore, the ratio of omega-3 versus omega-6 has wide effects on general health, and specific effects on immune function and inflammation, and mitosis (i.e., cell division).

What is an example of a hormone other than insulin that is able to control the enzyme delta-5-desaturase?
Output: glucagon

Input: British Empire
The independence of the Thirteen Colonies in North America in 1783 after the American War of Independence caused Britain to lose some of its oldest and most populous colonies. British attention soon turned towards Asia, Africa, and the Pacific. After the defeat of France in the Revolutionary and Napoleonic Wars (17921815), Britain emerged as the principal naval and imperial power of the 19th century (with London the largest city in the world from about 1830). Unchallenged at sea, British dominance was later described as Pax Britannica ("British Peace"), a period of relative peace in Europe and the world (18151914) during which the British Empire became the global hegemon and adopted the role of global policeman. In the early 19th century, the Industrial Revolution began to transform Britain; by the time of the Great Exhibition in 1851 the country was described as the "workshop of the world". The British Empire expanded to include India, large parts of Africa and many other territories throughout the world. Alongside the formal control it exerted over its own colonies, British dominance of much of world trade meant that it effectively controlled the economies of many regions, such as Asia and Latin America. Domestically, political attitudes favoured free trade and laissez-faire policies and a gradual widening of the voting franchise. During this century, the population increased at a dramatic rate, accompanied by rapid urbanisation, causing significant social and economic stresses. To seek new markets and sources of raw materials, the Conservative Party under Disraeli launched a period of imperialist expansion in Egypt, South Africa, and elsewhere. Canada, Australia, and New Zealand became self-governing dominions.

When did the Thirteen Colonies become independent from Britain?
Output: 1783

Input: St. John%27s, Newfoundland and Labrador
Of major Canadian cities, St. John's is the foggiest (124 days), windiest (24.3 km/h (15.1 mph) average speed), and cloudiest (1,497 hours of sunshine). St. John's experiences milder temperatures during the winter season in comparison to other Canadian cities, and has the mildest winter for any Canadian city outside of British Columbia. Precipitation is frequent and often heavy, falling year round. On average, summer is the driest season, with only occasional thunderstorm activity, and the wettest months are from October to January, with December the wettest single month, with nearly 165 millimetres of precipitation on average. This winter precipitation maximum is quite unusual for humid continental climates, which most commonly have a late spring or early summer precipitation maximum (for example, most of the Midwestern U.S.). Most heavy precipitation events in St. John's are the product of intense mid-latitude storms migrating from the Northeastern U.S. and New England states, and these are most common and intense from October to March, bringing heavy precipitation (commonly 4 to 8 centimetres of rainfall equivalent in a single storm), and strong winds. In winter, two or more types of precipitation (rain, freezing rain, sleet and snow) can fall from passage of a single storm. Snowfall is heavy, averaging nearly 335 centimetres per winter season. However, winter storms can bring changing precipitation types. Heavy snow can transition to heavy rain, melting the snow cover, and possibly back to snow or ice (perhaps briefly) all in the same storm, resulting in little or no net snow accumulation. Snow cover in St. John's is variable, and especially early in the winter season, may be slow to develop, but can extend deeply into the spring months (March, April). The St. John's area is subject to freezing rain (called "silver thaws"), the worst of which paralyzed the city over a three-day period in April 1984.

What Canadian city has the mildest winter temperature?
Output:
British Columbia