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In 1873, one of the first papers in modern medicine on the subject tried to explain the pathophysiology of the disease while one in 1872, concluded that asthma can be cured by rubbing the chest with chloroform liniment. Medical treatment in 1880, included the use of intravenous doses of a drug called pilocarpin. In 1886, F.H. Bosworth theorized a connection between asthma and hay fever. Epinephrine was first referred to in the treatment of asthma in 1905. Oral corticosteroids began to be used for this condition in the 1950s while inhaled corticosteroids and selective short acting beta agonist came into wide use in the 1960s.

What was first used as a cure for asthma?
Answer: by rubbing the chest with chloroform liniment
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Fryderyk may have had some piano instruction from his mother, but his first professional music tutor, from 1816 to 1821, was the Czech pianist Wojciech Zywny. His elder sister Ludwika also took lessons from Zywny, and occasionally played duets with her brother. It quickly became apparent that he was a child prodigy. By the age of seven Fryderyk had begun giving public concerts, and in 1817 he composed two polonaises, in G minor and B-flat major. His next work, a polonaise in A-flat major of 1821, dedicated to Zywny, is his earliest surviving musical manuscript.

What is the earliest surviving musical notation composed by Frederic?
Answer: a polonaise in A-flat major of 1821
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The Carboniferous was a time of active mountain building, as the supercontinent Pangea came together. The southern continents remained tied together in the supercontinent Gondwana, which collided with North America-Europe (Laurussia) along the present line of eastern North America. This continental collision resulted in the Hercynian orogeny in Europe, and the Alleghenian orogeny in North America; it also extended the newly uplifted Appalachians southwestward as the Ouachita Mountains. In the same time frame, much of present eastern Eurasian plate welded itself to Europe along the line of the Ural mountains. There were two major oceans in the Carboniferous the Panthalassa and Paleo-Tethys. Other minor oceans were shrinking and eventually closed the Rheic Ocean (closed by the assembly of South and North America), the small, shallow Ural Ocean (which was closed by the collision of Baltica, and Siberia continents, creating the Ural Mountains) and Proto-Tethys Ocean.

What was the continent that came to be North America and Europe called during the Carboniferous?
Answer:
Laurussia