Given a passage, construct a question on the basis of the information present in the passage. Construct the question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) it answer uses text phrases from the passage. Avoid creating questions that (i) can't be answered correctly without actually understanding the passage and (ii) uses the same words or phrases given in the passage.

Diffusion time () effect in diffusion measurements has been validated as a sensitive biomarker in liver fibrosis by rat models. To extend this finding to clinical study, a reliable imaging technique is highly desirable. This study aimed to develop an optimal stimulated echo acquisition mode (STEAM) diffusion-weighted imaging (DWI) method dedicated to human liver imaging on 3 Tesla (T) and preliminarily investigate the dependence effect in healthy volunteers.', 'STEAM DWI with single-shot echo planar imaging readout was used as it provided better signal-to-noise ratio (SNR) than spin echo DWI methods when a long was needed for liver imaging. Additionally, a slice-selection gradient reversal method was used for fat suppression. Motion compensation and SNR improvement strategies were used to further improve the image quality. Five b-values with three s were tested in 10 volunteers.', 'Effective fat suppression and motion compensation were reproducibly achieved in the optimized sequence. The signal decay generally became slower when the s increased. Obvious reduction of diffusion coefficients was observed with increasing s in the liver.
Do stimulated echo diffusion weighted imaging of the liver at 3 Tesla?