In this task, find the most appropriate number to replace the blank (indicated with _ ) and express it in words.

Example Input: Autism is _ to four times more likely to affect boys than girls.
Example Output: three

Example Input: Ozone leaves _ by-products except pure oxygen.
Example Output: no

Example Input: Diabetic women are _ times more likely to develop heart disease compared to non-diabetic women.
Example Output:
three