Question: Several organizations concerned with antimicrobial resistance are lobbying to eliminate the unnecessary use of antibiotics. The issues of misuse and overuse of antibiotics have been addressed by the formation of the US Interagency Task Force on Antimicrobial Resistance. This task force aims to actively address antimicrobial resistance, and is coordinated by the US Centers for Disease Control and Prevention, the Food and Drug Administration (FDA), and the National Institutes of Health (NIH), as well as other US agencies. An NGO campaign group is Keep Antibiotics Working. In France, an "Antibiotics are not automatic" government campaign started in 2002 and led to a marked reduction of unnecessary antibiotic prescriptions, especially in children.
Is there an answer to this question: Which agencies control this task force?

Answer: US Centers for Disease Control and Prevention, the Food and Drug Administration (FDA), and the National Institutes of Health (NIH)

Question: Articles 4653 of the Vienna Convention on the Law of Treaties set out the only ways that treaties can be invalidatedconsidered unenforceable and void under international law. A treaty will be invalidated due to either the circumstances by which a state party joined the treaty, or due to the content of the treaty itself. Invalidation is separate from withdrawal, suspension, or termination (addressed above), which all involve an alteration in the consent of the parties of a previously valid treaty rather than the invalidation of that consent in the first place.
Is there an answer to this question: In addition to the circumstances by which a state party joined a treaty, why might a treaty be invalidated?

Answer: the content of the treaty itself

Question: One hundred years after the fall of Constantinople in 1453, Pierre Belon described in his work Observations in 1553 that pissasphalto, a mixture of pitch and bitumen, was used in Dubrovnik for tarring of ships from where it was exported to a market place in Venice where it could be bought by anyone. An 1838 edition of Mechanics Magazine cites an early use of asphalt in France. A pamphlet dated 1621, by "a certain Monsieur d'Eyrinys, states that he had discovered the existence (of asphaltum) in large quantities in the vicinity of Neufchatel", and that he proposed to use it in a variety of ways "principally in the construction of air-proof granaries, and in protecting, by means of the arches, the water-courses in the city of Paris from the intrusion of dirt and filth", which at that time made the water unusable. "He expatiates also on the excellence of this material for forming level and durable terraces" in palaces, "the notion of forming such terraces in the streets not one likely to cross the brain of a Parisian of that generation". But it was generally neglected in France until the revolution of 1830. Then, in the 1830s, there was a surge of interest, and asphalt became widely used "for pavements, flat roofs, and the lining of cisterns, and in England, some use of it had been made of it for similar purposes". Its rise in Europe was "a sudden phenomenon", after natural deposits were found "in France at Osbann (BasRhin), the Parc (l'Ain) and the Puy-de-la-Poix (Puy-de-Dome)", although it could also be made artificially. One of the earliest uses in France was the laying of about 24,000 square yards of Seyssel asphalt at the Place de la Concorde in 1835.
Is there an answer to this question: In what year did a French magazine describe the use of asphalt?

Answer: 1838

Question: Intense media interest in the opinions and private lives of the royal family during the 1980s led to a series of sensational stories in the press, not all of which were entirely true. As Kelvin MacKenzie, editor of The Sun, told his staff: "Give me a Sunday for Monday splash on the Royals. Don't worry if it's not trueso long as there's not too much of a fuss about it afterwards." Newspaper editor Donald Trelford wrote in The Observer of 21 September 1986: "The royal soap opera has now reached such a pitch of public interest that the boundary between fact and fiction has been lost sight of ... it is not just that some papers don't check their facts or accept denials: they don't care if the stories are true or not." It was reported, most notably in The Sunday Times of 20 July 1986, that the Queen was worried that Margaret Thatcher's economic policies fostered social divisions and was alarmed by high unemployment, a series of riots, the violence of a miners' strike, and Thatcher's refusal to apply sanctions against the apartheid regime in South Africa. The sources of the rumours included royal aide Michael Shea and Commonwealth Secretary-General Shridath Ramphal, but Shea claimed his remarks were taken out of context and embellished by speculation. Thatcher reputedly said the Queen would vote for the Social Democratic PartyThatcher's political opponents. Thatcher's biographer John Campbell claimed "the report was a piece of journalistic mischief-making". Belying reports of acrimony between them, Thatcher later conveyed her personal admiration for the Queen, and the Queen gave two honours in her personal giftmembership in the Order of Merit and the Order of the Garterto Thatcher after her replacement as prime minister by John Major. Former Canadian Prime Minister Brian Mulroney said Elizabeth was a "behind the scenes force" in ending apartheid.
Is there an answer to this question: What did high public interest in the private lives of the royal family cause in the press?

Answer:
sensational stories