Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: The film opens with Soichi Negishi (Kenichi Matsuama) walking along side his mother to a small country train station. Negishi hopes to move to Japan, and realize his musical dreams, as a pop singer. As he rides away in the train, he sees his younger brother wave to him from a field.Now we are taken to a dark alleyway, where many alternative Japanese youths are entering a club called "Hell's Gate." Inside we see a death metal band(in rather flamboyant attire, and black and white make-up) preforming for a large crowd. This band, is Detroit Metal City. The singer, is then revealed to be Negashi, and why crowd surfing he narrates of his dislike of what he has become.The opening credits roll.We now see Negashi removing his makeup with a rag, and talking a fellow band mate, which is his lazy, bloomer obsessed drummer Terumichi Nishida . He begs Nishida to return a video-game he had let him borrow, out of fear of him losing it. Now the band's bassist Masayuki Wada speaks to Negashi about how well he believed the show had done.The dressing room door bursts open, and with a wild laugh the President Of Death Records(who also seems to be the band's manager) enters, and tosses a cigarette into a ash tray that Wada held, but it simply bounced out and went out of frame. She told them of how well they did, but in remorse Negashi played for her a tape of the pop music he wishes to make. Displeased, she kicked him.Now with a swollen mouth, Negashi leaves the dressing room in his normal attire, and pushes his way through the crowd of oblivious screaming fans, hoping to get a look at the band. He is hit, and begins to bleed from the nose. As he made his way up the stairs, he heard the fans talk of rumors they had heard about the lead singer Krauser, such as his ability to rape many women.Negashi is now on the street, and he is playing his pop music on an acoustic guitar, with people only stoping to glance at him, and then walk away. He stops playing and hears some pop music being played around the corner. As he goes to investigate he sees that the lead singer of the band was an old college friend, and then that a woman standing near him was his college crush Yuri Aikawa.He reflects on the old days, of them all sitting around playing music together, and of his quote "No music, No dream."He is soon at a record store, looking at the latest fashionable cd covers, when he sees Aikawa, and they began to chat, and make plans to meet later at a cafe. Then a blast of near-by music startles him, and he walks to the next isle to investigate. Several DMC fans had gathered to celebrate the release of a new single with head-banging, and loud music. Negashi dislikes the album cover, and complains about a quote that was in his name, that he never said. Aikawa then tells him of her distaste for metal, and how unfashionable she finds Detroit Metal City.Negashi is now in full attire with his band, doing an interview about the new single. His mind is off daydreaming about Aikawa when he realizes it is time for their date and he runs out of the interview to meet her. Negashi is now constantly going back and forth between the date, and the interview, each time forgetting to remove more and more of his DMC attire. With a feeling that negashi was going into the near-by club, she enters in hopes of finding him, but meets Krauser crowd surfing. Negashi in fear, tries to get the crowd to move him away from her, but the get him closer and closer, until he felt his wig began to slip off. The only thing he could do to cover himself, was to lift up her dress, showing her underwear. She calls him a pig, and walks out.Now Negashi is outside of a cafe, and is banging on the wall in
Question: Who is he in stage costume?

A: krauser
****
Q: Context: Monitoring global warming usually requires a Ph. D. and enough maths to glaze your eyes. But that Francisco Lopez and Ruby Nostrant track what climate change is doing to five different plants in Tucson, Arizona and they are only in the second grade. "We are collecting data because the weather is changing and the plants are blooming," Ruby explained. Scores of other students at Borton Primary Magnet School and Sunnyside High School in Tucson are heading outdoors to be part of a new scientific push to figure out how the biological timing of the earth is changing. It's a research project that the average person, even a kindergartner, can join in. The National Phenology Network is calling on volunteers to help track early spring blooms and eventually changes in animals caused by global warming. It's called Project Budburst. When it was first open to the public last year, thousands of people participated in 26 states. "All people can contribute to it by tracking the timing of flowering events or leaf-out events for plants and animals in their backyard," said Phenology Network director Jake Weltzin. He calls the volunteers "citizen-scientists." The idea is that tracking flowers blooming--especially lilacs ; which everyday people have helped track for decades--is fairly simple. The Website [Link] citizen _ science/budburst/index.html gives directions on what to look for in different parts of the country. University of Maryland professor David Inouye said it's so easy to figure out what's blooming that a lack of special knowledge isn't a problem. University of Arizona ecology graduate student Lisa Benton coordinated the Tucson high school students as they looked at plants five minutes from their high school. Each student has specific guidelines and she's been happy so far with the data she is getting. For his part, second-grader Francisco said he had fun helping out. "I like going out in the desert," he said. "I want to be an Einstein."
Question: Who is primary school student joining in the Project Budburst?

A: francisco lopez.
****
Q: Context: Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by extracellular plaques containing amyloid (A)-protein and intracellular tangles containing hyperphosphorylated Tau protein. Here, we describe the generation of inducible pluripotent stem cell lines from patients harboring the London familial AD (fAD) amyloid precursor protein (APP) mutation (V717I). We examine AD-relevant phenotypes following directed differentiation to forebrain neuronal fates vulnerable in AD. We observe that over differentiation time to mature neuronal fates, APP expression and levels of A increase dramatically. In both immature and mature neuronal fates, the APPV717I mutation affects both - and -secretase cleavage of APP. Although the mutation lies near the -secretase cleavage site in the transmembrane domain of APP, we find that -secretase cleavage of APP is elevated leading to generation of increased levels of both APPs and A. Furthermore, we find that this mutation alters the initial cleavage site of -secretase, resulting in an increased generation of both A42 and A38. In addition to altered APP processing, an increase in levels of total and phosphorylated Tau is observed in neurons with the APPV717I mutation. We show that treatment with A-specific antibodies early in culture reverses the phenotype of increased total Tau levels, implicating altered A production in fAD neurons in this phenotype. These studies use human neurons to reveal previously unrecognized effects of the most common fAD APP mutation and provide a model system for testing therapeutic strategies in the cell types most relevant to disease processes.
Question: Which disease the London mutation involved in?

A:
alzheimer's disease
****