In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: What element plays a physiological role in the prevention of gastroesophageal reflux?
Options: <1> Upper esophageal sphincter <2> Angle of His. <3> Hernia of Hiato. <4> Purkinje angle. <5> Pyloric sphincter
2

Question: Indicate in what clinical situation would NOT indicate beginning interferon beta in a patient diagnosed with multiple sclerosis:
Options: <1> Multiple recurring outbreaks. <2> Bad response to corticosteroids in outbreaks. <3> Having suffered a single outbreak of the disease with sequelae. <4> Be over 50 years old <5> A progressive primary clinical form.
5

Question: Insulin regulates the synthesis of fatty acids:
Options: <1> Activating phosphorylase <2> Dephosphorylating acetyl CoA carboxylase. <3> Inhibiting the formation of malonyl CoA. <4> Controlling the carnitine-acyl CoA transferase activity. <5> Activating the fatty acid synthetase.
2