You are given a new situation: Uncle Tom and uncle Sam both have high cholesterol. Uncle Tom is on statin drugs and uncle Sam is not. and a hint : Currently, millions of individuals with high cholesterol take a similar type of drug, known as a statin. The drug, an inhibitor of HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase), the rate limiting enzyme in cholesterol biosynthesis, decreases blood levels of cholesterol by induce the expression of low density lipoprotein (LDL) receptors in the liver. The increased levels of the LDL-receptors stimulate the catabolism of plasma LDL, removing cholesterol from plasma, which is an important determinant of atherosclerosis. You may know of people who take a statin to help with their cholesterol levels. However, these drugs probably work slightly differently in many of those people. In some, it lowers their cholesterol significantly; in others it may lower it only moderately; and in some, it may have no significant effect at all. (Luckily for those individuals, there are multiple versions of the statins, so different drugs can be tested to find the proper combination for that individual.) Why the difference? Because of the genetic background of all people; the different single nucleotide polymorphisms that make us all different. Pharmacogenomics, a combination of pharmacology and genomics (the study of the genome) that refers to the study of the relationship between pharmaceuticals and genetics, may explain and simplify this problem. Please answer this question : Which uncle takes an inhibitor that induces the expression of low density lipoprotein (LDL) receptors in the liver?
----
Answer: Tom

Q: You are given a new situation: Two neighboring towns from Texas produced their food in different ways. Silver town was sustainable and didn't use any fertilizers or pesticides, while Gold town did. and a hint : Rain dissolves fertilizer in the soil. Runoff carries it away. The fertilizer ends up in bodies of water, from ponds to oceans. Nitrogen is a fertilizer in the water. Since there is a lot of nitrogen, it causes algae to grow out of control. Pictured below is a pond covered with algae ( Figure below ). Algae use up carbon dioxide in the water. After the algae die, decomposers break down the dead tissue. The decomposers use up all the oxygen in the water. This creates a dead zone. A dead zone is an area in a body of water where nothing grows because there is too little oxygen. There is a large dead zone in the Gulf of Mexico ( Figure below ). The U.S. states outlined on the map have rivers that drain into the Gulf of Mexico. The rivers drain vast agricultural lands. The water carries fertilizer from these areas into the Gulf. Please answer this question : Which town caused fewer decomposers to use up all the oxygen in the water?
A: Silver

Question: You are given a new situation: Robert and Justin are both patients in the hospital who are suffering complications from their HIV infections. The doctor is trying to get information from both men about their diseases so he can create customized treatment plans for both men. After a few questions, the doctor discovers that Robert has been infected with HIV for many years, while Justin's infection is quite recent. and a hint : As time passes, the number of HIV copies keeps increasing, while the number of helper T cells keeps decreasing. The graph in Figure below shows how the number of T cells typically declines over a period of many years following the initial HIV infection. As the number of T cells decreases, so does the ability of the immune system to defend the body. As a result, an HIV-infected person develops frequent infections. Medicines can slow down the virus but not get rid of it, so there is no cure at present for HIV infections or AIDS. There also is no vaccine to immunize people against HIV infection, but scientists are working to develop one. Please answer this question : Who will develop infections more frequently?
Answer: Robert

[Q]: You are given a new situation: Ken is a microbiologist. He got two samples of yeasts, yeast A and yeast B, from two different businesses. Yeast A is used in a bakery, and yeast B is used in a brewery. He has to decide the characteristics of each yeast sample for further study. Interestingly, despite all his curiosity, Ken doesn't like any yeast to be around him. and a hint : Baker's yeast is the common name for the strains of yeast commonly used in baking bread and bakery products, serving as a leavening agent which causes the bread to rise (expand and become lighter and softer) by converting the fermentable sugars present in the dough into carbon dioxide and ethanol. Baker's yeast is of the species Saccharomyces cerevisiae,[1] and is the same species (but a different strain) as the kind commonly used in alcoholic fermentation, which is called brewer's yeast.[2] Baker's yeast is also a single-cell microorganism found on and around the human body. Please answer this question : If Ken doen't like any yeast around him, which yeast he should not worry about, yeas A or yeast B?
****
[A]: yeast A

input: Please answer the following: You are given a new situation: Spain and Italy participated in a global warming global forum this year. it turns out that Spain uses lots of fossil fuel and natural gas for their economy, while Italy relies on ecological alternatives. and a hint : The dangers of global warming are being increasingly studied by a wide global consortium of scientists. These scientists are increasingly concerned about the potential long-term effects of global warming on our natural environment and on the planet. Of particular concern is how climate change and global warming caused by anthropogenic, or human-made releases of greenhouse gases, most notably carbon dioxide, can act interactively, and have adverse effects upon the planet, its natural environment and humans' existence. It is clear the planet is warming, and warming rapidly. This is due to the greenhouse effect, which is caused by greenhouse gases, which trap heat inside the Earth's atmosphere because of their more complex molecular structure which allows them to vibrate and in turn trap heat and release it back towards the Earth. This warming is also responsible for the extinction of natural habitats, which in turn leads to a reduction in wildlife population.The most recent report from the Intergovernmental Panel on Climate Change (the group of the leading climate scientists in the world) concluded that the earth will warm anywhere from 2.7 to almost 11 degrees Fahrenheit (1.5 to 6 degrees Celsius) between 1990 and 2100. Please answer this question : Which country caused the reduction in wildlife population?
++++++++++
output: Spain

You are given a new situation: Pat has 2 acres of land next to Tim's property. Tim's land is of similar size. The clay soil on Tim's property is very alkaline, so he had to amend it with aluminum salts to make it more acidic in order to grow crops. The soil on Pat's parcel has a good structure and high infiltration capacity. Pat gets twice as much food of his land every year. and a hint : Alkali, or Alkaline, soils are clay soils with high pH (> 8.5), a poor soil structure and a low infiltration capacity. Often they have a hard calcareous layer at 0.5 to 1 metre depth. Alkali soils owe their unfavorable physico-chemical properties mainly to the dominating presence of sodium carbonate, which causes the soil to swell[1] and difficult to clarify/settle. They derive their name from the alkali metal group of elements, to which sodium belongs, and which can induce basicity. Sometimes these soils are also referred to as alkaline sodic soils. Alkaline soils are basic, but not all basic soils are alkaline. Please answer this question : Which of these two parcels has low presence of sodium carbonate in the soil?
----
Answer:
Pat's