Second-generation antihistamines cross the blood--brain barrier to a much lower degree than the first-generation antihistamines. Their main benefit is they primarily affect peripheral histamine receptors and therefore are less sedating. However, high doses can still induce drowsiness through acting on the central nervous system. Some second-generation antihistamines, notably cetirizine, can interact with CNS psychoactive drugs such as bupropion and benzodiazepines.

Choose your answer: Is the following statement correct based on the text

do second generation antihistamines cross the blood brain barrier

OPTIONS: 1. no 2. yes
2.