Given a passage and a query based on the passage, generate an unambiguous, concise and simple answer to the query from information in the passage. Note that the answer may not be present in exact form.

[EX Q]: Fluoride supplements were developed in the 1950s based on the incorrect and outdated notions that (a) fluoride's benefit to teeth comes from being swallowed during childhood, and that (b) children in unfluoridated communities have a deficiency of fluoride intake. For example, the use of a series of four or more topical applications should be considered for a patient with a severe caries problem. Likewise, a reduced topical application time of 30 seconds as opposed to four minutes may be adequate to maintain a patient with little or no current caries activity. Check with your child's doctor for any other special instructions. 1 Your child can eat and drink right after the fluoride varnish is applied. But only give your child soft foods and cold or warm (not hot) foods or liquids. 2 Do not brush or floss teeth for at least 4 to 6 hours. Fluoride varnish is a highly concentrated form of fluoride which is applied to the tooth's surface, by a dentist, dental hygienist or other health care professional, as a type of topical fluoride therapy.[1] It is not a permanent varnish but due to its adherent nature it is able to stay in contact with the tooth surface for several hours. When is Fluoride Varnish not used? Fluoride varnish is not used if there are noticeable sores in the mouth or on the gums. It is also not used if there is an allergy to one of the ingredients in the varnish or to pine nuts. If you have any questions, talk to your doctor or dentist. The first use of adjusted fluoride in water for caries control began in 1945 and 1946 in the United States and Canada, when the fluoride concentration was adjusted in the drinking water supplying four communities (2--5). Water fluoridation reduces cavities in children, while efficacy in adults is less clear. A Cochrane review estimates a reduction in cavities when water fluoridation was used by children who had no access to other sources of fluoride to be 35% in baby teeth and 26% in permanent teeth. The evidence quality was poor. The CDC recommends that in communities where natural fluoride levels are high, parents should give kids water from other sources. The ADA also recognizes that infants need less fluoride than older kids and adults. Some infants may be getting too much fluoride in the water used to reconstitute infant formula. Fluoride supplements can be prescribed for children ages 6 months to 16 years who are at high risk for tooth decay and whose primary drinking water has a low fluoride concentration. 2, 21 Tablets and lozenges are manufactured with 1.0, 0.5, or 0.25 mg fluoride. 2, 3 Most supplements contain sodium fluoride as the active ingredient. 2 To maximize the topical effect of fluoride, tablets and lozenges are intended to be chewed or sucked for 12 minutes before being swallowed; 2, 3, 5 for ... A 1992 census found that, for U.S. public water supply systems reporting the type of compound used, 63% of the population received water fluoridated with fluorosilicic acid, 28% with sodium fluorosilicate, and 9% with sodium fluoride. Query: at what age should fluoride be used
[EX A]: Fluoride supplements should be prescribed for children ages 6 months to 16 years.

[EX Q]: Average cost to build the average hotel is about $22.2 million (325 square feet. Room: 13'x25', full bathroom. 115 rooms). Find here detailed information about build a hotel costs. Average cost to build the average hotel is about $22.2 million (325 square feet. Room: 13'x25', full bathroom. 115 rooms). Includes the option to view the costs of the 18 other countries presented, typical for their different construction requirements. View a typical hotel cost schedule The cost schedule shown is typical of the cost information we provide on the members site. We have conducted our own market research amongst overseas buyers in Spain that suggests that people are prepared to pay between 20% and 30% more for an energy efficient building. An energy efficient design needn't cost any more and it could add substantially to the value of your investment. A definition and explanation of building costs or construction costs, how RICS is involved with building costs, and a list of building costs websites from a wide range of countries. Construction Cost per Square Foot 4-7 Story Apartment Building At the lowest end of the cost spectrum is the 4-7 story apartment building. Similar to the Hotels, taking advantage of the vertical construction, apartment buildings also are not required to have the variety of functions that are necessary in a hotel. Data source: Reed Construction Data RSMeans/Charts: Reed Construction Data CanaData. 1 Construction Cost per Square Foot of 2-3 Story Motel. 2 Construction Cost per Square Foot for 4-7 Story Hotel. 3 Construction Cost per Square Foot 4-7 Story Apartment Building. Anybody contemplating buying a property in Spain now needs to have therapy. Renting is the only sensible way to live here now. Trouble is nobody believes you. After 30 years here, and yes, I do speak Spanish, my advice is save yourself a lot of grief and think again. Spain Accommodation Cost. Accommodation in Spain would cost you around 20-50 euros if you're staying in backpacker hostels. If hotels is your thing then be ready to pay more. I was visiting friends during my entire trip so I didn't really spend anything for accommodation. Spain Party Cost. It's not that expensive to go out in Spain. A glass of beer with tapas would cost you between 1.5 2.5 euros. Spanish people also love to have a botellon which is basically a group of people drinking outside in public, usually in parks. An extra few thousand euros spent on a purchase may represent better value for money than spending the money on building work. It's often cheaper to buy a restored or partly restored property rather than a ruin in need of total restoration, unless you're going to do most of the work yourself. Cost model: Hotels By Phil Churchman of Davis Langdon, an Aecom company 2013-04-18T06:00:00 Converting an existing building is often the best option for opening new hotels. Query: average cost of building a hotel in spain
[EX A]: The average cost of building a hotel in Spain is 1.5 to 2.5 euros.

[EX Q]: Example of the closed system: If you are registered with the Democratic Party, you may vote for Democratic candidates, nonpartisan candidates and local or state measures. You cannot vote for a candidate from any other party in the Primary Election. Example of the open system: The Republican Party can announce they are going to open their Primary Election so people who are not registered with any party can vote for Republican candidates in addition to, the nonpartisan candidates and local or state measures. You can also check for your voter record online. Please note that an information card or other correspondence confirming your voter registration status does not qualify as photo identification. For information on qualified identification for voting in person, or how to obtain a Voter Photo Identification card, please visit: elections.virginia.gov/voterID or call toll free at (800) 552-9745 or TTY: 711 The registration deadline to vote in the next election is 21 days prior to election day. You are not eligible to register to vote if: You are serving a sentence or on parole or probation, as a result of a conviction of an indictable offense under state or federal law. 1 Note: If you are no longer serving a sentence, or no longer on parole or probation..., you CAN vote in NJ by completing a new voter registration form (linked above). You only lose your right to vote while on parole, probation or serving a sentence due to a conviction for an indictable offense under any federal or state laws. How can I cancel voter registration of a close relative? Absentee Services This directs voters who want to vote by absentee ballot to services based on their situation. Click the link that describes your situation Uniformed service or overseas citizen voter You can vote in U.S. elections if you: Are a U.S. citizen; Meet your state's residency requirements. You can be homeless and still meet these requirements. Are 18 years old on or before Election Day. In some states, you can register to vote before you turn 18 if you will be 18 by Election Day. Are registered to vote by your state's voter registration deadline. North Dakota does not require voter registration. Conditional Voter Registration. In elections conducted by your county elections official, you can "conditionally" register and vote at your county elections office after the 15-day voter registration deadline. For more information please go to Conditional Voter Registration. You should update your registration if you move, change your name or mailing address, or want to select or change a political party. Absentee Voting Students attending an out-of-state college or voters traveling during an election can still receive a ballot. 18 by next General Election (note: you can vote at age 17 in a primary, if you'll be 18 by the next General Election) Maryland. You may register to vote if you are at least 16 years old but cannot vote unless you will be at least 18 years old by the next general election. Massachusetts. Be at least 18 years of age on or before the next election. Permanent Early Voting: If you have a permanent physical disability, you may request to be placed on the Permanent Early Voter List (PEVL). You will be mailed a ballot for each election that you are eligible for and can vote from the comfort and convenience of your own home. Register to be a permanent early voter online Register to be a permanent early voter by mail (PDF) If you were registered to vote before you were convicted, you must complete a new voter registration form (linked above) once you have served your time. If you are a pre-trial detainee or on bail pending appeal, you do not lose your right to vote. If you have any questions, please contact your county commissioner of registration. Additional Voter Registration Information and Forms Query: how early can you register to vote
[EX A]:
You can register to your vote 21 days prior to election day.