TASK DEFINITION: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
PROBLEM: Background: Nurses leaving their jobs and the profession are an issue of international concern, with supplydemand gaps for nurses reported to be widening. There is a large body of existing literature, much of which is already in review form. In order to advance the usefulness of the literature for nurse and human resource managers, we undertook an overview (review of systematic reviews). The aim of the overview was to identify high quality evidence of the determinants and consequences of turnover in adult nursing. Methods: Reviews were identified which were published between 1990 and January 2015 in English using electronic databases (the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, Applied Social Sciences Index and Abstracts, CINAHL plus and SCOPUS) and forward searching. All stages of the review were conducted in parallel by two reviewers. Reviews were quality appraised using the Assessment of Multiple Systematic Reviews and their findings narratively synthesised. Results: Nine reviews were included. We found that the current evidence is incomplete and has a number of important limitations. However, a body of moderate quality review evidence does exist giving a picture of multiple determinants of turnover in adult nursing, with -at the individual level -nurse stress and dissatisfaction being important factors and -at the organisational level -managerial style and supervisory support factors holding most weight. The consequences of turnover are only described in economic terms, but are considered significant. In making a quality assessment of the review as well as considering the quality of the included primary studies and specificity in the outcomes they measure, the overview found that the evidence is not as definitive as previously presented from individual reviews. Further research is required, of rigorous research design, whether quantitative or qualitative, particularly against the outcome of actual turnover as opposed to intention to leave.

SOLUTION: The determinants and consequences of adult nursing staff turnover: a systematic review of systematic reviews

PROBLEM: An RNA-based, non-cytopathic replicon vector system, based on the flavivirus Kunjin, has shown considerable promise as a new vaccine delivery system. Here we describe the testing in mice of four different SIVmac239 gag vaccines delivered by Kunjin replicon virus-like-particles. The four vaccines encoded the wild type gag gene, an RNA-optimised gag gene, a codon-optimised gag gene and a modified gag-pol gene construct. The vaccines behaved quite differently for induction of effector memory and central memory responses, for mediation of protection, and with respect to insert stability, with the SIV gag-pol vaccine providing the optimal performance. These results illustrate that for an RNA-based vector the RNA sequence of the antigen can have profound and unforeseen consequences on vaccine behaviour.

SOLUTION: Kunjin replicon-based simian immunodeficiency virus gag vaccines

PROBLEM: At the height of the SARS 1 crisis in spring 2003, the World Health Organization (WHO) and China fought a silent battle over the prevalence of two competing norms in global health governance. On the one hand, the established norm of sovereignty, particularly the principle of non-interference, had structured a regime for dealing with infectious disease outbreaks that provided ground rules of conduct but ascribed decision-making authority to member states alone. It explicitly ruled out foreign or supranational interference. On the other hand, the emerging norm of global health security was built on an understanding of infectious disease outbreaks as international security problems requiring supranational coordination and governance capacity. In effect, it implied the subordination of national economic and political interests to global disease detection and containment efforts. Its proponents thus sought a prominent role for the WHO in taking decisions in response to global health emergencies which would entail interference with state sovereignty. By the time of the SARS outbreak, this normative tension was far from being resolved. On the contrary, the two central actors in this episode, the Chinese government and the WHO secretariat, turned it into a manifest norm conflict by demonstrating incompatible positional differences over the relative priority of the two norms. 2 Intriguingly, however, neither China nor the WHO resorted to discursive modes of contestation by justifying their respective positions with reference to normative arguments. Almost exclusively, they displayed incompatible normative expectations in the way they put the norms into practice. The WHO acted as if the norm of global health security had already been widely accepted, supplanting those aspects of the sovereignty norm with which it conflicted. Without prior legal or political authorization to do so, the organization took a set of unprecedented measures. Most importantly, it issued travel warnings for affected regions, devised emergency recommendations, and put pressure on governments (the Chinese in particular) to comply-clearly challenging the non-interference 1 Severe Acute Respiratory Syndrome. 2 On the manifestation of norm conflicts, see Michael Zurn, Benjamin Faude and Christian Kreuder-Sonnen, Overlapping spheres of authority and interface conflicts in the global order: introducing a DFG research group, WZB

SOLUTION:
China vs the WHO: a behavioural norm conflict in the SARS crisis