You will be given a definition of a task first, then an example. Follow the example to solve a new instance of the task.
Given a scientific passage and an answer, generate a question for the given answer.

Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Solution: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Why? The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.

New input: Passage: Scientists do the same thing when they classify , or put into categories, living things. Scientists classify organisms not only by their physical features, but also by how closely related they are. Lions and tigers look like each other more than they look like bears, but are lions and tigers related? Evolutionarily speaking, yes. Evolution is the change in a species over time. Lions and tigers both evolved from a common ancestor. So it turns out that the two cats are actually more closely related to each other than to bears. How an organism looks and how it is related to other organisms determines how it is classified. Answer: evolution
Solution:
What is the change in a species over time?