Given the task definition and input, reply with output. This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Hellenistic culture produced seats of learning throughout the Mediterranean. Hellenistic science differed from Greek science in at least two ways: first, it benefited from the cross-fertilization of Greek ideas with those that had developed in the larger Hellenistic world; secondly, to some extent, it was supported by royal patrons in the kingdoms founded by Alexander's successors. Especially important to Hellenistic science was the city of Alexandria in Egypt, which became a major center of scientific research in the 3rd century BC. Hellenistic scholars frequently employed the principles developed in earlier Greek thought: the application of mathematics and deliberate empirical research, in their scientific investigations.
The Royal patrons of Alexander's successors supported what type of science?