Input: Middle Ages
In European history, the Middle Ages or medieval period lasted from the 5th to the 15th century. It began with the collapse of the Western Roman Empire and merged into the Renaissance and the Age of Discovery. The Middle Ages is the middle period of the three traditional divisions of Western history: Antiquity, Medieval period, and Modern period. The Medieval period is itself subdivided into the Early, the High, and the Late Middle Ages.

In what century did the Middle Ages begin?
Output: 5th

Input: Alsace
Alsace is one of the most conservative regions of France. It is one of just two regions in metropolitan France where the conservative right won the 2004 region elections and thus controls the Alsace Regional Council. Conservative leader Nicolas Sarkozy got his best score in Alsace (over 65%) in the second round of the French presidential elections of 2007. The president of the Regional Council is Philippe Richert, a member of the Union for a Popular Movement, elected in the 2010 regional election. The frequently changing status of the region throughout history has left its mark on modern day politics in terms of a particular interest in national identity issues. Alsace is also one of the most pro-EU regions of France. It was one of the few French regions that voted 'yes' to the European Constitution in 2005.

Alsace was one of the few to vote for this measure from France, what was it?
Output: European Constitution in 2005

Input: Spectre (2015 film)
Filming started in Austria in December 2014, with production taking in the area around Soldenincluding the Otztal Glacier Road, Rettenbach glacier and the adjacent ski resort and cable car stationand Obertilliach and Lake Altaussee, before concluding in February 2015. Scenes filmed in Austria centred on the Ice Q Restaurant, standing in for the fictional Hoffler Klinik, a private medical clinic in the Austrian Alps. Filming included an action scene featuring a Land Rover Defender Bigfoot and a Range Rover Sport. Production was temporarily halted first by an injury to Craig, who sprained his knee whilst shooting a fight scene, and later by an accident involving a filming vehicle that saw three crew members injured, at least one of them seriously.

What building was used in the film as the Hoffler Klinik?
Output: Ice Q Restaurant

Input: Pharmaceutical industry
A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Canadian professor Frederick Banting and his student Charles Best repeated this study, and found that injections of pancreatic extract reversed the symptoms produced by pancreas removal. Soon, the extract was demonstrated to work in people, but development of insulin therapy as a routine medical procedure was delayed by difficulties in producing the material in sufficient quantity and with reproducible purity. The researchers sought assistance from industrial collaborators at Eli Lilly and Co. based on the company's experience with large scale purification of biological materials. Chemist George Walden of Eli Lilly and Company found that careful adjustment of the pH of the extract allowed a relatively pure grade of insulin to be produced. Under pressure from Toronto University and a potential patent challenge by academic scientists who had independently developed a similar purification method, an agreement was reached for non-exclusive production of insulin by multiple companies. Prior to the discovery and widespread availability of insulin therapy the life expectancy of diabetics was only a few months.

What is diabetes caused from?
Output:
absence of a substance normally produced by the pancreas