Context and question: Genetics compression algorithms are the latest generation of lossless algorithms that compress data (typically sequences of nucleotides) using both conventional compression algorithms and genetic algorithms adapted to the specific datatype. In 2012, a team of scientists from Johns Hopkins University published a genetic compression algorithm that does not use a reference genome for compression. HAPZIPPER was tailored for HapMap data and achieves over 20-fold compression (95% reduction in file size), providing 2- to 4-fold better compression and in much faster time than the leading general-purpose compression utilities. For this, Chanda, Elhaik, and Bader introduced MAF based encoding (MAFE), which reduces the heterogeneity of the dataset by sorting SNPs by their minor allele frequency, thus homogenizing the dataset. Other algorithms in 2009 and 2013 (DNAZip and GenomeZip) have compression ratios of up to 1200-foldallowing 6 billion basepair diploid human genomes to be stored in 2.5 megabytes (relative to a reference genome or averaged over many genomes).
What encoding reduces the heterogenelty of a dataset by sorting megabytes?
Answer: unanswerable
Context and question: A mummified man, determined to be 5,000 years old, was discovered on a glacier at the AustrianItalian border in 1991. By the 6th century BC, the Celtic La Tene culture was well established. Hannibal famously crossed the Alps with a herd of elephants, and the Romans had settlements in the region. In 1800 Napoleon crossed one of the mountain passes with an army of 40,000. The 18th and 19th centuries saw an influx of naturalists, writers, and artists, in particular the Romantics, followed by the golden age of alpinism as mountaineers began to ascend the peaks. In World War II, Adolf Hitler kept a base of operation in the Bavarian Alps throughout the war.
Where was Adolf Hitlers base of operation during World War 2?
Answer: Bavarian Alps
Context and question: The High Middle Ages was the formative period in the history of the modern Western state. Kings in France, England, and Spain consolidated their power, and set up lasting governing institutions. New kingdoms such as Hungary and Poland, after their conversion to Christianity, became Central European powers. The Magyars settled Hungary around 900 under King Arpad (d. c. 907) after a series of invasions in the 9th century. The papacy, long attached to an ideology of independence from secular kings, first asserted its claim to temporal authority over the entire Christian world; the Papal Monarchy reached its apogee in the early 13th century under the pontificate of Innocent III (pope 11981216). Northern Crusades and the advance of Christian kingdoms and military orders into previously pagan regions in the Baltic and Finnic north-east brought the forced assimilation of numerous native peoples into European culture.
When did the papacy of Innocent III begin?
Answer:
1198