The first legislation providing federal authority for regulating pesticides was enacted in 1910; however, decades later during the 1940s manufacturers began to produce large amounts of synthetic pesticides and their use became widespread. Some sources consider the 1940s and 1950s to have been the start of the "pesticide era." Although the U.S. Environmental Protection Agency was established in 1970 and amendments to the pesticide law in 1972, pesticide use has increased 50-fold since 1950 and 2.3 million tonnes (2.5 million short tons) of industrial pesticides are now[when?] used each year. Seventy-five percent of all pesticides in the world are used in developed countries, but use in developing countries is increasing. A study of USA pesticide use trends through 1997 was published in 2003 by the National Science Foundation's Center for Integrated Pest Management.
Countries which are established use what amount of pesticides?
Seventy-five percent

The majority of studies indicate antibiotics do interfere with contraceptive pills, such as clinical studies that suggest the failure rate of contraceptive pills caused by antibiotics is very low (about 1%). In cases where antibacterials have been suggested to affect the efficiency of birth control pills, such as for the broad-spectrum antibacterial rifampicin, these cases may be due to an increase in the activities of hepatic liver enzymes' causing increased breakdown of the pill's active ingredients. Effects on the intestinal flora, which might result in reduced absorption of estrogens in the colon, have also been suggested, but such suggestions have been inconclusive and controversial. Clinicians have recommended that extra contraceptive measures be applied during therapies using antibacterials that are suspected to interact with oral contraceptives.
What percent is the failure rate of contraceptive pills?
about 1%

In the general election, Kerry was initially favored to defeat the Republican candidate, former State Representative Paul W. Cronin, and conservative Democrat Roger P. Durkin, who ran as an Independent. A week after the primary, one poll put Kerry 26-points ahead of Cronin. His campaign called for a national health insurance system, discounted prescription drugs for the unemployed, a jobs programme to clean up the Merrimack River and rent controls in Lowell and Lawrence. A major obstacle, however, was the district's leading newspaper, the conservative The Sun. The paper editorialized against him. It also ran critical news stories about his out-of-state contributions and his "carpetbagging", because he had only moved into the district in April. Subsequently released "Watergate" Oval Office tape recordings of the Nixon White House showed that defeating Kerry's candidacy had attracted the personal attention of President Nixon. Kerry himself asserts that Nixon sent operatives to Lowell to help derail his campaign.
How far ahead of Cronin did Kerry poll?
26-points