In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Input: Consider Input: Societies in the 21st century require more proactive management of risks in many areas owing to the complexities people have built into socioeconomic systems, ranging from science and technology, economics, and finance to education, entertainment, and tourism infrastructure. All these systems thrive on stability, which can easily be challenged by unexpected risks. This study compares zooanthroponosis and climate change-induced sea level rise through a cost-benefit analysis in Korea. Borrowing from other methodological approaches, this study shows that the cost-benefit estimation is consistent with the existing macroeconomic speculations, which assume potential loss of GDP due to the two risks. This paper also presents a policy alternative of creating research institutions specializing in the two risks from a cost-benefit perspective as a prerequisite for the "Creative Economy".

Output: Comparing the economic effects of climate change and zooanthroponosis in Korea: Prerequisites for the creative economy?

Input: Consider Input: Bacterial and viral infections occur early and recurrently in life and thereby impose a substantial disease burden. Besides causing clinical symptoms, a potential role of infection in the development of the asthma syndrome later in life has also been suggested. However, whether bacterial and viral infections unmask host factors in children at risk of asthma or whether they directly cause asthma remains unclear; both viewpoints could be justifi ed, but the underlying mechanisms are complex and poorly understood. Recently, the role of the bacterial microbiome has been emphasised. But data are still sparse and future studies are needed for defi nitive conclusions to be made. In this Review, we discuss present knowledge of viruses and bacteria that infect and colonise the respiratory tract and mucosal surfaces, including their timepoint of action, host factors related to infection, and their eff ect on childhood asthma. Childhood asthma could be the result of a combination of altered host susceptibility and infectious agents.

Output: Prenatal and childhood infections: implications for the development and treatment of childhood asthma

Input: Consider Input: Mice expressing the Cre recombinase from within the lysozyme M locus (LysMcre mice) were purchased from the Jackson Laboratory (Strain # 004781). Atg5 flox/flox and Atg5 flox/flox +LysMcre mice with two different backgrounds ( Figures 1C and 1D from mixed 129-C57BL/6 mice and all the others from C57BL/6 mice) were used for this study and consistent phenotypes between different backgrounds were observed. To generate bone marrow derived macrophages (BMDM), mouse bone marrows were isolated and cultured on non-tissue-culture treated plate for 7 days in BMDM media (Dulbeco's Modified Eagle Medium, 10% fetal bovine serum, 5% horse serum, 10% CMG14-12 (Takeshita et al., 2000) , 1x MEM nonessential amino acids, 1mM sodium pyruvate, 2 mM L-glutamine). At day 7, adherent BMDMs were dissociated from the plate and set up for experiment. At day 10, media were changed to fresh media and IFN were treated if necessary. At day 11, cells were used for MNV infection or autophagy analysis. Depending on the deletion status of floxed gene (e.g. Atg7 flox/flox +LysMcre), BMDMs were cultured up to 21 days and used for infection study. For EMCV and MHV, BMDMs were prepared as previously described (Zhao et al., 2007) .
Output: Cell Host & Microbe Supplemental Information Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma