Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Is [ The incidence of postoperative nausea and vomiting effected by routinely applied manual pre-oxygenation during induction of anesthesia ]?
Answer: Since neither routine pre-intubation positive pressure mask ventilation nor the medical qualification of the anesthesilogist affect the incidence of PONV neither variable needs to be taken into account in studies concerning PONV.

Answer: no

Question: Question: Is serum Reg-Ialpha suitable marker of metabolic syndrome?
Answer: Our study, for the first time, indicates that serum Reg-1alpha is not useful for the diagnosis of metabolic syndrome (Tab. 3, Ref. 7).

Answer: no

Question: Question: Does mitral regurgitation reduce systemic coagulation activity in patients with rheumatic heart disease?
Answer: Plasma D-dimer levels correlated with the embolic risk in mitral valve disease and non-valvular AF. The highest levels were found in patients with MS+AF and non-valvular AF. Severe MR decreased the D-dimer levels in MS and/or AF to control levels.

Answer:
yes