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Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
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Paragraph: "Independents need to know they can invest their vote in the Democratic Party," Carter said Tuesday during his annual report at his post-presidential center and library in Atlanta, where he offered caution about the political consequences should Democrats "move to a very liberal program, like universal health care." That's delicate and, Carter admitted, even contradictory advice coming from the 93-year-old former president, and it underscores the complicated political calculations for Democrats as they prepare for the November midterms and look ahead to the 2020 presidential election. "Rosie and I voted for Bernie Sanders in the past," Carter noted. He was referring to his wife, Rosalynn, and their support for the Vermont senator, an independent who identifies as a democratic socialist, over establishment favorite Hillary Clinton in the 2016 Democratic presidential primary. At another point, he pointed to California's environmental policies limits on carbon emissions, stiffer fuel-efficiency standards as the model for combating climate change. Still, Carter stressed, Democrats nationally must "appeal to independents" who are souring on the current administration. Trump's job approval rating, according to Gallup, has dipped to 40 percent, mostly because of declining support among independents. Carter alluded to arguments from self-identified progressives that Democrats will sacrifice votes on the left if they don't embrace the liberal base: "I don't think any Democrat is going to vote against a Democratic nominee," and he insisted that he's not asking the left to sacrifice its goals, only to see that winning elections is necessary to accomplish any of them. There is some historical irony in Carter's analysis. He came to the White House in 1976 from the moderate wing of the Democratic Party, and he clashed with party liberals, drawing a spirited primary challenge in 1980 from Massachusetts Sen. Ted Kennedy. Carter prevailed, but he was wounded, abandoned by Kennedy's most liberal supporters and unable to win over independents who helped deliver a landslide for Republican Ronald Reagan. Carter's latest handicapping comes near the conclusion of a midterm primary season that has seen Democratic primary voters move the party to the left. In some states and districts, that means nominating full-throated advocates of single-payer health care, a $15 minimum wage and abolishing or at least overhauling the federal Immigration and Customs Enforcement agency. In other races, it means nominees who back more cautious moves to the left, such as background checks before certain gun purchases, a "public option" health insurance plan to compete alongside private insurance policies, step raises for the minimum wage and an immigration overhaul that offers legal status to some immigrants in the country illegally. Carter did not delve into those distinctions, instead offering a sweeping condemnation of his latest successor to remind Democrats of the stakes. He denounced the administration's latest environmental policy proposal to make it easier for energy companies to release methane gas that contributes to climate change. He singled out Trump's policy of separating immigrant families at the border, including those seeking asylum. "America is inherently committed to human rights, and I think in the future we will let that prevail," Carter said, "but for the next two years, I can't predict the imprisoned children are going to be any better off unfortunately." Carter has previously criticized Trump for his repeated falsehoods, and he's chided Trump for his hardline support for Israel over Palestinians. Yet Carter has found common ground with Trump on other foreign policy fronts, and did so again Tuesday. While avoiding any mention of the special counsel's investigation into whether Trump's presidential campaign coordinated with Russia in the 2016 U.S. election, Carter said he has engaged for years with Russian President Vladimir Putin concerning the ongoing Syrian civil war. "I have his email address," Carter said, adding that he and Putin share the same Russian river as their favorite spot for salmon fishing. That friendship, Carter said, means when Russia and other nations hold multilateral talks about the Syrian conflict, "Quite often they invite the Carter Center. ... They do not invite the U.S. government." Carter also praised Trump for meeting with North Korean leader Kim Jong Un. Carter repeated his frustrations with the last Democratic president, Barack Obama, for not engaging more directly with the insular Asian nation. Carter said he's not sure Trump has made real progress yet with North Korea, but he endorsed calls for the U.S. to formally declare an end to the Korean War and normalize relations with Pyongyang. "Let them be part of the community of nations," he said. "I think that would be enough in itself to bring an end to the nuclear program in North Korea." ___ Follow Barrow on Twitter at https://twitter.com/BillBarrowAP Claim: Jimmy Carter: To beat Trump, Dems cannot scare off moderates.
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Former President Jimmy Carter sees little hope for the U.S. to change its human rights and environmental policies as long as Donald Trump is in the White House, but he has a warning for his fellow Democrats looking to oust the current administration: Don't go too far to the left.

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Paragraph: Mentions cost for one year of Herceptin as $40,000-$50,000. Mentions quantitative benefit of 9 weeks of Herceptin vs. no Herceptin with certain chemotherapy. Also, while no women in the Herceptin group had cardiac failure at 3 years, the follow-up period may not be long-enough to determine the effects of chemotherapy and Herceptin on the heart. Mentions potential harms of Herceptin on the heart, especially when given after certain chemotherapy. The story does not mention that there were side effects with certain chemotherapy drugs and doses needed to be decreased during the course of the trial. One aspect of this trial focused on randomization of women with Her2/neu overexpression to 9 weeks of Herceptin or no Herceptin immediately following breast cancer surgery. The drug was given in conjunction with certain types of chemotherapy, but before radiation and chemotherapy regimens known to damage the heart. The journalist states the Herceptin was given "prior to chemotherapy", which is not completely accurate. There is an adequate mention of the study design and discussion of disease-free survival at 3 years follow-up. Good job putting the results into context of other trials, and into context of how this may or may not change providers' practice. The story could have better stated the limitations of analysis for such a small subgroup 116 in each arm. Appropriately discusses the percentage of women who are eligible for Herceptin due to overexpression of HER2/neu. The story would have been helped by some context for the risk these women face. As Herceptin is used earlier and earlier these women have less to gain because they have less risk to begin with. Relative risk reductions may be very high but the absolute is not as big. Sources in addition to study authors are cited. No mention that this trial was funded in part by pharmaceutical companies. Some study investigators also receive research funding drug companies. Other doctors cited express caution about the early results of Herceptin studies, so there is some balance to the piece. The women in this trial had undergone breast cancer surgery and those with ER+ tumors were taking Tamoxifen. This is not explicitly mentioned, only that treatment took place following surgery. Still OK. Herceptin is only FDA approved to treat advanced breast cancer, but is used in clinical trials in early-stage breast cancer. This is not mentioned in the story. Novel use of Herceptin for short-term treatment prior to anthracycline chemotherapy. No evidence that this story relies on a press release. Claim: Short stint of Herceptin holds promise for breast cancer
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This story discusses the results of a recent study involving women with high-risk early breast cancer (node positive or >2cm, age younger than 66 there were 25 year olds on the trial). One aspect of this trial focused on the short-term use of Herceptin with chemotherapy. Women with overexpression of the HER2/neu gene, as measured by the CISH immunohistochemistry, were randomly assigned 9 weeks of Herceptin or no Herceptin immediately following breast cancer surgery and in conjunction with certain types of chemotherapy. This regimen of treatment differed from other trials in which Herceptin was given for 12 months following chemotherapy. In this study, the drug was given in conjunction with certain types of chemotherapy, but before radiation and chemotherapy regimens known to damage the heart. The journalist states the Herceptin was given "prior to chemotherapy," which is not completely accurate. Herceptin is only FDA approved to treat advanced breast cancer, but it is used in clinical trials in early-stage breast cancer. However, this is not mentioned in the story. There is adequate discussion of the study design and reporting of disease-free survival at 3 years follow-up. There was little discussion in the piece of the side effects of chemotherapy as reported in the trial, but the addition of Herceptin was the main focus of the story. While the journalist provides quantitative benefit of 9 weeks of Herceptin vs. no Herceptin, and notes no cardiac failure in the Herceptin group, the follow-up period of 3 years may not be long-enough to determine the effects of chemotherapy and Herceptin on the heart. Overall, the journalist did a good job describing the randomization, as well as putting the results into context of other trials, and into context of how this may or may not change providers' practice. The story could have better stated the limitations of analysis for such a small subgroup (116 in each arm). The small sample randomized to Herceptin certainly warrants more study, and although the relative benefits were large, these women still had fairly good recurrence free survival 80% w/o and 90% with so although it looks like that will translate to overall survival. The question for women with overexpression of the HER/neu gene is: How much do you want to do to avoid recurrence? Sources in addition to the study investigators are cited, which provides some balance to the piece, however, there is no mention that the trial was funded in part by pharmaceutical companies. Some study investigators also receive research funding from drug companies.

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Paragraph: On June 21 2020, the Facebook page "The Runic Witch" shared the following meme, which described a garden in England "dedicated entirely to plants that can kill you":At the bottom of the meme was a photograph of a black gate, the archway of which read "The Poison Garden." Both doors featured a skull and crossbones symbol and the words "these plants can kill." Text at the top read:There's a garden in England dedicated entirely to plants that are deadly and can kill you. It's the most dangerous garden in the world. It holds over 100 killers [such as hemlock], strychnine, and nightshade.The Alnwick Gardenis a "complex of formal gardens" not far from the Scottish border. It contains a number of sub-sections, including a massive treehouse, a cherry orchard, a bamboo labyrinth, and water features:Number nine on the above "Map Key" is marked to the left of the center fountain, and a rendering of the iron gates seen in the meme is visible.The Poison Garden was added in 2005, and a page on the Garden's visitor site says of the deadlier plant section:The Alnwick Garden plays host to the small but deadly Poison Gardenfilled exclusively with around 100 toxic, intoxicating, and narcotic plants. The boundaries of the Poison Garden are kept behind black iron gates, only open on guided tours.Visitors are strictly prohibited from smelling, touching, or tasting any plants, although some people still occasionally faint from inhaling toxic fumes while walking in the garden.An archived version of the page shed a bit more light onto the garden's creation:It's not often that the Home Office becomes involved with plants in the setting of a public garden, but in this instance a number of the 'inmates' have to have their very own license in order to be there at all.Many of the plants are already well-known for their medicinal properties, but as its creator, the Duchess of Northumberland said:'I wondered why so many gardens around the world focused on the healing power of plants rather than their ability to kill I felt that most children I knew would be more interested in hearing how a plant killed, how long it would take you to die if you ate it and how gruesome and painful the death might be.'Another since updated section, titled "Intoxicating inhabitants," described some of the plants growing in the garden as the ones mentioned in the meme:There are over 100 plants of varying deadliness grown in the Poison Garden. Some of the plants are beautiful despite being deadly, and other look so harmless it is hard to imagine their dangerous, even fatal, qualities.Nux vomica's Latin name implies much, but it perhaps rings more bells as strychnine. Interestingly, hemlock, a poison in its own right, can be used as an antidote to Strychnine, but don't tell Socrates, who was sent to his death with a cup of hemlock.Those of a certain age will be familiar with Castor Oil, which is made from the plant Ricinus communis, but a single seed from the same plant will kill an adult in the most horrible way. Ricin causes nausea, severe vomiting, convulsions and subsequent disintegration of the kidneys, liver and spleenIn 2014,Smithsonian Magazineprofiled the Poison Garden and spoke toJane Percy, the Duchess of Northumberland about the macabre project's inspiration:The duchess thought she might want to include an apothecary garden, but a trip to Italy set her on a slightly different course. After visiting the infamous Medici poison garden, the duchess became enthralled with the idea of creating a garden of plants that could kill instead of heal. Another tripthis one to the archeological site of the largest hospital in medieval Scotland, where the duchess learned about soporific sponges soaked in henbane, opium and hemlock used to anesthetize amputees during 15th-century surgeriesreinforced her interest in creating a garden of lethal plants."I thought, 'This is a way to interest children,'" she says. "Children don't care that aspirin comes from a bark of a tree. What's really interesting is to know how a plant kills you, and how the patient dies, and what you feel like before you die."[]"What's extraordinary about the plants is that it's the most common ones that people don't know are killers," the duchess says. Visitors are often surprised to learn that the laurel hedge, nearly ubiquitous in English gardens, can be highly toxic. But some visitors have had experience with laurel's sinister sidethe duchess has heard a few talk about how, after loading up their cars with pruned laurel leaves to take to the dump, drivers have fallen asleep behind the wheel of their car from the toxic fumes the branches emit.In the meme, plants in the nightshade family (which also contains potatoes, tomatoes, and eggplant) were mentioned. In the article, a more specific explanation appeared alongside a detail about the garden's other interesting inhabitants:As part of the Poison Garden's educational mission, the duchess grows a variety of drugs, from cannabis to cocaine (derived from the leaves of the coca plant), which she and garden guides use as a jumping-off point for drug education. "It's a way of educating children without having them realize they're being educated," she says.Other poisonous plants might be less well-known to visitors, but are no less potent. One of the duchess's favorite plants is Brugmansia, or angel's trumpet, a member of the Solanaceae family (which includes deadly nightshade) that grows in the wild in South America. "It's an amazing aphrodisiac before it kills you," she says, explaining that Victorian ladies would often keep a flower from the plant on their card tables and add small amounts of its pollen to their tea to incite an LSD-like trip. "[Angel's trumpet] is an amazing way to die because it's quite pain-free," the duchess says. "A great killer is usually an incredible aphrodisiac."As such, the "Poison Garden" meme was both popular and largely accurate. The Poison Garden is a sub-attraction as part of the larger Alnwick Garden, and it is grown behind the depicted, imposing iron gates. Among the deadly plants in it are hemlock, Nux vomica (strychnine), andRicinus communis (ricin).Comments Claim: There's a garden in England dedicated entirely to plants that are deadly and can kill you. It's the most dangerous garden in the world. It holds over 100 killers [such as hemlock], strychnine, and nightshade.
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Is There a Garden in England Dedicated Solely to Deadly Plants Called the 'Poison Garden'?