Context and question: Some of these estimates also take into account the opportunity cost of investing capital many years before revenues are realized (see Time-value of money). Because of the very long time needed for discovery, development, and approval of pharmaceuticals, these costs can accumulate to nearly half the total expense. A direct consequence within the pharmaceutical industry value chain is that major pharmaceutical multinationals tend to increasingly outsource risks related to fundamental research, which somewhat reshapes the industry ecosystem with biotechnology companies playing an increasingly important role, and overall strategies being redefined accordingly. Some approved drugs, such as those based on re-formulation of an existing active ingredient (also referred to as Line-extensions) are much less expensive to develop.
What is the consequence in the value chain?
Answer: increasingly outsource risks related to fundamental research
Context and question: In 1972, the French physicist Francis Perrin discovered fifteen ancient and no longer active natural nuclear fission reactors in three separate ore deposits at the Oklo mine in Gabon, West Africa, collectively known as the Oklo Fossil Reactors. The ore deposit is 1.7 billion years old; then, uranium-235 constituted about 3% of the total uranium on Earth. This is high enough to permit a sustained nuclear fission chain reaction to occur, provided other supporting conditions exist. The capacity of the surrounding sediment to contain the nuclear waste products has been cited by the U.S. federal government as supporting evidence for the feasibility to store spent nuclear fuel at the Yucca Mountain nuclear waste repository.
Of what nationality wasn't Perrin?
Answer: unanswerable
Context and question: After receiving his J.D. from Boston College Law School, Kerry worked in Massachusetts as an Assistant District Attorney. He served as Lieutenant Governor of Massachusetts under Michael Dukakis from 1983 to 1985 and was elected to the U.S. Senate in 1984 and was sworn in the following January. On the Senate Foreign Relations Committee, he led a series of hearings from 1987 to 1989 which were a precursor to the IranContra affair. Kerry was re-elected to additional terms in 1990, 1996, 2002 and 2008. In 2002, Kerry voted to authorize the President "to use force, if necessary, to disarm Saddam Hussein", but warned that the administration should exhaust its diplomatic avenues before launching war.
When did Kerry become a Senator?
Answer:
1984