Add punctuation: Unsure about which type of PFX file you have Do you want to know exactly what it is who created it and how to open it
A: Unsure about which type of PFX file you have? Do you want to know exactly what it is, who created it, and how to open it?

Add punctuation: A continental breakfast can be requested for an extra charge
A: A continental breakfast can be requested for an extra charge.

Add punctuation: Most are reversible if the abuser stops taking the drugs but some are permanent such as voice deepening in females
A:
Most are reversible if the abuser stops taking the drugs, but some are permanent, such as voice deepening in females.