Answer the following question: I want to test the ability of students to read a passage and answer questions about it. Could you please come up with a good question for the passage "Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing."?
Answer:
When was it suggested that one gene makes one protein?