Given a scientific passage and an answer, generate a question for the given answer.

Example input: Passage: A frameshift mutation is a deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence. Deletions remove nucleotides, and insertions add nucleotides. Consider the following sequence of bases in RNA:. Answer: nucleotides.
Example output: A frameshift mutation is a deletion or insertion of one or more of what that changes the reading frame of the base sequence?
Example explanation: The science passage defines frame mutation and the main compoment here is nucleotides. Hence the generated question is apt.
Q: Passage: If you look at your hand, what do you see? Of course, you see skin, which consists of cells. But what are skin cells made of? Like all living cells, they are made of matter. In fact, all things are made of matter. Matter is anything that takes up space and has mass. Matter, in turn, is made up of chemical substances. In this lesson you will learn about the chemical substances that make up living things. Answer: matter
A:
What term is used to describe anything that takes up space and has mass?