Given the task definition, example input & output, solve the new input case.
In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Example: Question: A 13-year-old girl is operated on due to Hirschsprung illness at 3 months of age. Which of the following tumors is more likely to be present?
Options: <1> Abdominal neuroblastoma <2> Wilms tumor <3> Mesoblastic nephroma <4> Familial thyroid medullary carcinoma.
Output: 2
The answer to the given question should be a tumor, therefore Wilms tumor is the correct answer for the given question.

New input case for you: Question: A 33-year-old woman with a loss of 6 kg in the last 4 months, asthenia and anorexia. Amenorrhea for 2 months. The hormonal results indicate a basal cortisol serum concentration of 108 nmol / l (baseline normal value 115-550) and 123 nmol / l after stimulation with ACTH. The baseline plasma concentration of ACTH is 48 pmol / l (normal value: 2-12). What is the most likely diagnosis?
Options: <1> Primary adrenal insufficiency. <2> Secondary adrenal insufficiency. <3> Tertiary adrenal insufficiency due to hypothalamic lesion. <4> ACTH-producing pituitary tumor (corticotropinoma). <5> More tests should be done since the diagnosis is inconclusive.
Output:
1