Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: Schimke immuno-osseous dysplasia (OMIM 242900) is an uncommon autosomal-recessive multisystem disease caused by mutations in SMARCAL1 (swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1), a gene encoding a putative chromatin remodeling protein. Neurologic manifestations identified to date relate to enhanced atherosclerosis and cerebrovascular disease. Based on a clinical survey, we determined that half of Schimke immuno-osseous dysplasia patients have a small head circumference, and 15% have social, language, motor, or cognitive abnormalities. Postmortem examination of 2 Schimke immuno-osseous dysplasia patients showed low brain weights and subtle brain histologic abnormalities suggestive of perturbed neuron-glial migration such as heterotopia, irregular cortical thickness, incomplete gyral formation, and poor definition of cortical layers. We found that SMARCAL1 is highly expressed in the developing and adult mouse and human brain, including neural precursors and neuronal lineage cells. These observations suggest that SMARCAL1 deficiency may influence brain development and function in addition to its previously recognized effect on cerebral circulation.

Answer: Mutations in which gene cause Schimke immune-osseous dysplasia?

Question: Two forms of neurofibromatosis, type 1 (NF1) and type 2 (NF2) are connected with genes localized on chromosomes 17 and 22, respectively. The genes that are inactivated in neurofibromatosis code for the proteins neurofibromine and merline, respectively. Since inactivation leads to neoplasia, they are called tumour suppressor genes. Neurofibromine shows resemblances to proteins that serve to inactivate oncogenes. Merline has a relationship with proteins that connect the cytoskeleton and the cell membrane. The precise function of the proteins is still unknown. The NF1 gene is characterized by extraordinarily high sensitivity to mutation; half the NF1 patients have not inherited the disease. In the familial form of neurofibromatosis, a mutated gene is inherited and the normal allele in the tumour is inactivated, making tumour growth possible. In the sporadic form of neurofibromatosis, both normal alleles are inactivated locally in the tissue so that a tumour develops in that place.

Answer: Which is the gene mutated in type 1 neurofibromatosis?

Question: Johann Bayer used the Greek letters Alpha to Eta to label the most prominent eight stars in the constellation, designating two stars as Delta (named Delta1 and Delta2). John Flamsteed numbered fourteen stars, discerning a third star he named Delta3; his star 12 Canis Minoris was not found subsequently. In Bayers 1603 work Uranometria, Procyon is located on the dogs belly, and Gomeisa on its neck. Gamma Canis Minoris, Epsilon Canis Minoris and Eta Canis Minoris lie nearby, marking the dogs neck, crown and chest respectively. Although it has an apparent magnitude of 4.34, Gamma Canis Minoris is an orange stellar classification giant star of spectral class K3-III C, which lies away. Its colour is obvious when seen through binoculars. It is a multiple system, consisting of the spectroscopic binary Gamma A and three optical companions, Gamma B, magnitude 13; Gamma C, magnitude 12; and Gamma D, magnitude 10. The two components of Gamma A orbit each other every 389.2 days, with an eccentric orbit that takes their separation between 2.3 and 1.4 astronomical units (AU). Epsilon Canis Minoris is a yellow bright giant of spectral class G6.5IIb of magnitude of 4.99. It lies from Earth, with 13 times the diameter and 750 times the luminosity of the Sun. Eta Canis Minoris is a giant of spectral class F0III of magnitude 5.24, which has a yellowish hue when viewed through binoculars as well as a faint companion of magnitude 11.1. Located 4 arcseconds from the primary, the companion star is actually around 440 AU from the main star and takes around 5000 years to orbit it.

Answer:
Who labeled more starts, Johann Bayer or John Flamsteed?