You will be given a definition of a task first, then some input of the task.
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does active CREB1 promote a malignant TGF2 autocrine loop in glioblastoma?
Answer: TGF is considered a promising therapeutic target, and several clinical trials using TGF inhibitors are generating encouraging results. Here, we discerned the molecular mechanisms responsible for the aberrantly high levels of TGF2 found in certain tumors, and we propose biomarkers to predict the clinical response to anti-TGF therapies.
Output:
yes