Given an abstract, generate a keyword (a noun phrase) that best describes the focus or contribution of the paper. Such keywords can be directly from the given abstract or outside it.
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Question: Abstract: Pertussigen is a protein toxin of Bordetella pertussis that acts as a powerful stimulator of the intensity and duration of delayed-type hypersensitivity (DTH) in mice. This study describes the potent in vivo effect of pertussigen on the levels of antigen-specific macrophage-activating lymphokine(s); lymphokine(s) was measured by the stimulation of macrophage procoagulant activity (mPCA), or plasminogen activator (PA) activity. Lymphoid cells were removed from immunized animals and cultured with specific antigen, keyhole limpet hemocyanin, ovalbumin, or human gamma-globulin. The culture supernatants were then incubated with the monocyte-like cell line WEHI-265 to measure mPCA or with WEHI-265 or resident peritoneal macrophages to measure PA activity. Mice were given pertussigen at the time of immunization, and the subsequent generation by lymphocyte supernatants of both of these macrophage activities proved to be greatly enhanced; the effect of pertussigen was antigen specific. Pertussigen thus induces an increase in lymphokine(s) production responsible for the in vitro increase in macrophage mPCA and PA activity and which may be responsible for some of the potent immune effects of this agent in vivo.

Answer: Animal

Question: Abstract: Stabilization of the ankle joint is used as a deterrent to injury, however, insufficient or excessive ankle control can cause negative effects. This study determined the effects of systematic changes in ankle and subtalar joint stabilization on performance through an obstacle course. Data were collected on six subjects as they completed two test procedures. Ankle range of motion in the sagittal and frontal planes was determined using a modified Inman apparatus. Completion time through an obstacle course, set up on a basketball court, was used as a measure of performance. High-top basketball shoes were constructed with pockets which allowed strips of plastic (stiffeners) to be positioned just anterior and posterior to the medial and lateral malleoli. Four shoe conditions were used including the shoe with no stiffeners. Significant differences (P less than 0.05) in eversion, flexion, and inversion were found between the shoe conditions. A general trend of decreased range of motion with increased restriction was observed. Significant differences (P less than 0.05) in performance were found between the shoe conditions, with a general trend of increased times with increased restriction. These results indicate that systematic changes in the range of motion of the ankle and subtalar joints can measurably affect performance.

Answer: Adult

Question: Abstract: We have developed an anesthesia information system (AIS) that supports the anesthesiologist in monitoring and recording during a surgical operation. In development of the system, emphasis was placed on providing an anesthesiologist-computer interface that can be adapted to typical situations during anesthesia and to individual user behavior. One main feature of this interface is the integration of the input and output of information. The only device for interaction between the anesthesiologist and the AIS is a touch-sensitive, high-resolution color display screen. The anesthesiologist enters information by touching virtual function keys displayed on the screen. A data window displays all data generated over time, such as automatically recorded vital signs, including blood pressure, heart rate, and rectal and esophageal temperatures, and manually entered variables, such as administered drugs, and ventilator settings. The information gathered by the AIS is presented on the cathode ray tube in several pages. A main distributor page gives an overall view of the content of every work page. A one-page record of the anesthesia is automatically plotted on a multicolor digital plotter during the operation. An example of the use of the AIS is presented from a field test of the system during which it was evaluated in the operating room without interfering with the ongoing operation. Medical staff who used the AIS imitated the anesthesiologist's recording and information search behavior but did not have responsibility for the conduct of the anesthetic.

Answer:
Anesthesia Department, Hospital