In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
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Question: Paragraph: The development of intestinal lesions after inoculation with Brachyspira hyodysenteriae was followed by repeated endoscopy and biopsy sampling through a caecal cannula. Seven eight-week-old pigs were cannulated and inoculated, two were cannulated but not inoculated, and two pigs were inoculated but not cannulated. Endoscopy, biopsy, and blood sampling to determine SAA (serum amyloid A), haptoglobin, cortisol, and WBC counts were performed at scheduled time-points. At the third day of disease, endoscopy showed a hyperaemic, perturbed mucosa and excessive amount of mucus. Histologically, crypt hyperplasia, depletion of goblet cell mucus, and erosions were noted. Simultaneously, elevated acute phase proteins and circulating monocytes, and decreased number of intraepithelial CD3 + cells were observed. After five days the pigs recovered. Intestinal lesions were demarcated and interspersed among apparently normal mucosa and blood parameters returned to initial values. Endoscopy through an intestinal cannula made it possible to follow the development of intestinal alterations in vivo and describe the sequential events during the course of swine dysentery. The number of animals used in a study could thus be minimised and the precision of the experiment increased.
Title: Consecutive pathological and immunological alterations during experimentally induced swine dysentery - A study performed by repeated endoscopy and biopsy samplings through an intestinal cannula

Answer: True

Question: Paragraph: As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual willingness to take precautions may be influenced by global factors, such as news media, or local factors, such as infected family members or friends. Here, we compare three modes of epidemiological decisionmaking in the midst of a growing outbreak using network-based mathematical models that capture plausible heterogeneity in human contact patterns. Individuals decide whether to adopt a recommended intervention based on overall disease prevalence, the proportion of social contacts infected, or the number of social contacts infected. While all strategies can substantially mitigate transmission, vaccinating (or self isolating) based on the number of infected acquaintances is expected to prevent the most infections while requiring the fewest intervention resources. Unlike the other strategies, it has a substantial herd effect, providing indirect protection to a large fraction of the population. misinformation from the "anti-vaxxer" movement [8, [11] [12] [13] . Recently, there have been calls for a special government commission on vaccine safety, despite overwhelming scientific consensus that vaccines are both safe and effective [12, [14] [15] [16] . As outbreaks unfold, people can take a variety precautionary measures to avoid infection, including immunization and social distancing [1, [17] [18] [19] . They often judge personal risk based on their impressions of overall disease prevalence and severity [2, [20] [21] [22] [23] . When infection risk appears low, small risks of adverse effects from the vaccine can seem relatively important and cause vaccine coverage to drop below levels required to control transmission. A variety of other factors can influence the perceived utility of disease prevention, including epidemiological news and rumors, costs of vaccination and other control measures, trust in health professionals, government agencies, media and non-official information sources, as well as societal pressure to ensure the health of one's children [24] [25] [26] [27] [28] [29] . Studies have shown that media reports about outbreaks that specify numbers of cases, hospitalizations or deaths, can influence avoidance behavior and contact patterns at both individual and community levels. In some cases, oversimplified or erroneous media reports regarding flawed vaccines can trigger panic and increases in vaccine hesitancy [30] [31] [32] [33] . For both seasonal and pandemic influenza, such interactions between vaccination decision-making and transmission dynamics can profoundly shape the course of epidemics [20, [34] [35] [36] . Individual intervention decisions can have far-reaching effects. For example, vaccination protects not only the immunized individual, but also social contacts who might have been infected by the individual. Social distancing decisions may break chains of transmission by protecting the decision-maker and more generally disrupting social dynamics. Following [37, 38] , we refer to this indirect protection as a herd effect. Although previously equated to the reduction in incidence in the unimmunized population [38], we quantify the herd effect of an intervention effort by estimating the number of infections averted per vaccine administered (or per individual social distancing action). The general phenomenon in which individual intervention actions reduce the risk of infection to others has also been called vaccination efficiency, vaccination effectiveness, herd immunity, and indirect protection [37] [38] [39] [40] . The magnitude of the herd effect will critically depend on contact patterns [41, 42]. Measures taken by gregarious individuals may have greater immediate benefits than those taken by solitary individuals, with downstream epidemiological consequences modulated by the full social network [43, 44] . Contact patterns may also influence the decision-making process itself, by constraining epidemiological perspectives. When gauging infection risk, individuals may consider global information (e.g., from news media) or local first-hand encounters with disease (e.g., infected acquaintances, friends or family members) [30, 31] . While traditional compartmental models assume homogeneity in both epidemiological risks and intervention benefits, network-based models provide a tractable framework for studying the complex interplay between contact networks, intervention decision making and disease transmission [34, [45] [46] [47] [48] [49] [50] [51] . Here, we investigate the epidemiological impacts of different decision paradigms using a network-based SIR epidemic model, in which individuals also make vaccination or social distancing choices based on their perceived epidemiological risks. Depending on the decision model, they estimate either overall disease prevalence, their number of infected social contacts, or their fraction of infected social contacts. When the perceived threat is sufficiently high, they take a measure that immediately affords full protection for the duration of the epidemic. We compare the efficacy of these three different paradigms across a range of diseases in a realistically heterogeneous network, and show that the most naive model-simply counting one's infected contacts-affords the most epidemiological protection using the least amount of resources (e.g., vaccinations or economic costs associated with social distancing). Local risk perception enhances epidemic control PLOS ONE | https://doi.
Title: Local risk perception enhances epidemic control

Answer: True

Question: Paragraph: ORF la of lactate dehydrogenase-elevating virus, strain P (LDV-P), encodes a protein of 2206 amino acids. Eisenberg hydrophobic moment analysis of the protein predicted the presence of eleven transmembrane segments in the C-terminal half of the molecule (amino acids 980-1852) that flank the serine protease domain, cDNAs encoding ORF la protein segments encompassing transmembrane segments 5 to 11 and its amphipathic C-terminal end as well as the N-terminal 80 amino acids of the downstream ORF lb protein were transcribed and the transcripts in vitro translated in the absence and presence of microsomal membranes. The synthesis of the protein products with putative transmembrane segments was enhanced by the presence of the microsomal membranes and the proteins became membrane associated. When synthesized in the absence of membranes they were recovered in the supernatant upon ultracentrifugation of the translation reaction mixtures, whereas they were recovered in the membrane pellet when synthesized in the presence of membranes. Furthermore, the latter proteins were not released from the membranes by disruption of the membrane vesicles in carbonate buffer, pH 11.5, and large portions of the proteins were resistant to digestion by trypsin, chymotrypsin and proteinase K. No N-glycosylation was observed and only little, if any, processing of the protein by the putative serine protease. The results indicate that the C-terminal half of the ORF la protein represents a non-glycosylated integral membrane protein. Potential modes of synthesis and function of the protein are discussed. In addition, the results showed that the synthesis of the ORF la protein was generally terminated at its termination codon, but that read-through into the ORF lb gene occurred with low frequency.
Title: Membrane association of the C-terminal half of the open reading frame la protein of lactate dehydrogenase-elevating virus Brief Report

Answer:
True