psui3905/ncbi_genes_summary huggingface dataset:
ZCCHC10, Official Symbol ZCCHC10provided by HGNC Official Full Name zinc finger CCHC-type containing 10provided by HGNC Primary source HGNC:HGNC:25954 See related Ensembl:ENSG00000155329 AllianceGenome:HGNC:25954 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable nucleic acid binding activity and zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 8.3), testis (RPKM 8.2) and 25 other tissues See more Orthologs mouse all
ZCCHC12, Official Symbol ZCCHC12provided by HGNC Official Full Name zinc finger CCHC-type containing 12provided by HGNC Primary source HGNC:HGNC:27273 See related Ensembl:ENSG00000174460 MIM:300701; AllianceGenome:HGNC:27273 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIZN; SIZN1; PNMA7A Summary This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Expression Biased expression in endometrium (RPKM 50.3), brain (RPKM 9.1) and 1 other tissue See more Orthologs mouse all
ZCCHC13, Official Symbol ZCCHC13provided by HGNC Official Full Name zinc finger CCHC-type containing 13provided by HGNC Primary source HGNC:HGNC:31749 See related Ensembl:ENSG00000187969 AllianceGenome:HGNC:31749 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNBP2; ZNF9L Summary This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 3. However, the CDS of this intronless gene remains relatively intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. The encoded protein contains six CCHC-type zinc fingers, and is thus thought to function as a transcription factor. [provided by RefSeq, May 2010] Orthologs mouse all
ZCCHC14, Official Symbol ZCCHC14provided by HGNC Official Full Name zinc finger CCHC-type containing 14provided by HGNC Primary source HGNC:HGNC:24134 See related Ensembl:ENSG00000140948 AllianceGenome:HGNC:24134 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDG29; BDG-29 Summary Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 26.9), ovary (RPKM 7.6) and 24 other tissues See more Orthologs mouse all
ZCCHC17, Official Symbol ZCCHC17provided by HGNC Official Full Name zinc finger CCHC-type containing 17provided by HGNC Primary source HGNC:HGNC:30246 See related Ensembl:ENSG00000121766 MIM:619744; AllianceGenome:HGNC:30246 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PS1D; pNO40; HSPC251 Summary Enables identical protein binding activity. Predicted to be involved in RNA stabilization. Predicted to be located in nucleolus. Predicted to be part of cytosolic large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in heart (RPKM 23.1), brain (RPKM 18.8) and 24 other tissues See more Orthologs mouse all
ZCCHC18, Official Symbol ZCCHC18provided by HGNC Official Full Name zinc finger CCHC-type containing 18provided by HGNC Primary source HGNC:HGNC:32459 See related Ensembl:ENSG00000166707 AllianceGenome:HGNC:32459 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIZN2; PNMA7B Summary Predicted to enable metal ion binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 1.7), brain (RPKM 1.6) and 25 other tissues See more Orthologs mouse all
ZCCHC2, Official Symbol ZCCHC2provided by HGNC Official Full Name zinc finger CCHC-type containing 2provided by HGNC Primary source HGNC:HGNC:22916 See related Ensembl:ENSG00000141664 MIM:620095; AllianceGenome:HGNC:22916 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C18orf49 Summary Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.7), salivary gland (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
ZCCHC24, Official Symbol ZCCHC24provided by HGNC Official Full Name zinc finger CCHC-type containing 24provided by HGNC Primary source HGNC:HGNC:26911 See related Ensembl:ENSG00000165424 AllianceGenome:HGNC:26911 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Z3CXXC8; C10orf56 Summary Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 26.2), fat (RPKM 23.1) and 23 other tissues See more Orthologs mouse all
ZCCHC3, Official Symbol ZCCHC3provided by HGNC Official Full Name zinc finger CCHC-type containing 3provided by HGNC Primary source HGNC:HGNC:16230 See related Ensembl:ENSG00000247315 MIM:618326; AllianceGenome:HGNC:16230 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf99 Summary Enables double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; detection of virus; and positive regulation of RIG-I signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
ZCCHC4, Official Symbol ZCCHC4provided by HGNC Official Full Name zinc finger CCHC-type containing 4provided by HGNC Primary source HGNC:HGNC:22917 See related Ensembl:ENSG00000168228 MIM:611792; AllianceGenome:HGNC:22917 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZGRF4; HSPC052 Summary Enables S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 1.4), ovary (RPKM 1.3) and 25 other tissues See more Orthologs mouse all
ZCCHC7, Official Symbol ZCCHC7provided by HGNC Official Full Name zinc finger CCHC-type containing 7provided by HGNC Primary source HGNC:HGNC:26209 See related Ensembl:ENSG00000147905 AllianceGenome:HGNC:26209 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIR1; HSPC086 Summary Enables RNA binding activity. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 3.6), testis (RPKM 2.2) and 25 other tissues See more Orthologs mouse all
ZCCHC8, Official Symbol ZCCHC8provided by HGNC Official Full Name zinc finger CCHC-type containing 8provided by HGNC Primary source HGNC:HGNC:25265 See related Ensembl:ENSG00000033030 MIM:616381; AllianceGenome:HGNC:25265 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFBMFT5 Summary This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in bone marrow (RPKM 13.2), testis (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
ZCCHC9, Official Symbol ZCCHC9provided by HGNC Official Full Name zinc finger CCHC-type containing 9provided by HGNC Primary source HGNC:HGNC:25424 See related Ensembl:ENSG00000131732 MIM:620382; AllianceGenome:HGNC:25424 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPP1R41 Summary Enables RNA binding activity. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 8.9), appendix (RPKM 8.7) and 25 other tissues See more Orthologs mouse all
ZCRB1, Official Symbol ZCRB1provided by HGNC Official Full Name zinc finger CCHC-type and RNA binding motif containing 1provided by HGNC Primary source HGNC:HGNC:29620 See related Ensembl:ENSG00000139168 MIM:610750; AllianceGenome:HGNC:29620 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MADP1; RBM36; MADP-1; SNRNP31; ZCCHC19 Summary Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 32.6), brain (RPKM 19.2) and 25 other tissues See more Orthologs mouse all
ZCRB1P1, Official Symbol ZCRB1P1provided by HGNC Official Full Name ZCRB1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:54987 See related AllianceGenome:HGNC:54987 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZCWPW1, Official Symbol ZCWPW1provided by HGNC Official Full Name zinc finger CW-type and PWWP domain containing 1provided by HGNC Primary source HGNC:HGNC:23486 See related Ensembl:ENSG00000078487 MIM:618900; AllianceGenome:HGNC:23486 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZCW1 Summary Enables methyl-CpG binding activity and methylated histone binding activity. Predicted to be involved in meiosis I; positive regulation of DNA metabolic process; and spermatogenesis. Predicted to act upstream of or within homologous chromosome pairing at meiosis. Predicted to be located in XY body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 25.2), thyroid (RPKM 2.9) and 16 other tissues See more Orthologs mouse all
ZCWPW2, Official Symbol ZCWPW2provided by HGNC Official Full Name zinc finger CW-type and PWWP domain containing 2provided by HGNC Primary source HGNC:HGNC:23574 See related Ensembl:ENSG00000206559 AllianceGenome:HGNC:23574 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZCW2 Summary Enables methylated histone binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 1.3), fat (RPKM 0.5) and 25 other tissues See more Orthologs mouse all
ZDBF2, Official Symbol ZDBF2provided by HGNC Official Full Name zinc finger DBF-type containing 2provided by HGNC Primary source HGNC:HGNC:29313 See related Ensembl:ENSG00000204186 MIM:617059; AllianceGenome:HGNC:29313 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Slx9 Summary This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in adrenal (RPKM 4.6), brain (RPKM 4.3) and 25 other tissues See more Orthologs mouse all
ZDHHC1, Official Symbol ZDHHC1provided by HGNC Official Full Name zinc finger DHHC-type containing 1provided by HGNC Primary source HGNC:HGNC:17916 See related Ensembl:ENSG00000159714 AllianceGenome:HGNC:17916 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC-1; ZNF377; C16orf1; HSU90653 Summary Enables palmitoyltransferase activity. Involved in antiviral innate immune response; positive regulation of defense response to virus by host; and protein palmitoylation. Located in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 6.2), testis (RPKM 6.1) and 24 other tissues See more Orthologs mouse all
ZDHHC11, Official Symbol ZDHHC11provided by HGNC Official Full Name zinc finger DHHC-type containing 11provided by HGNC Primary source HGNC:HGNC:19158 See related Ensembl:ENSG00000188818 AllianceGenome:HGNC:19158 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF399 Summary Enables signaling adaptor activity. Involved in antiviral innate immune response and positive regulation of defense response to virus by host. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lung (RPKM 2.8), duodenum (RPKM 2.5) and 24 other tissues See more Orthologs all
ZDHHC11B, Official Symbol ZDHHC11Bprovided by HGNC Official Full Name zinc finger DHHC-type containing 11Bprovided by HGNC Primary source HGNC:HGNC:32962 See related Ensembl:ENSG00000206077 AllianceGenome:HGNC:32962 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC-11B Summary Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in several processes, including antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Predicted to be located in endosome membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lung (RPKM 4.3), brain (RPKM 3.1) and 23 other tissues See more Orthologs all
ZDHHC12, Official Symbol ZDHHC12provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 12provided by HGNC Primary source HGNC:HGNC:19159 See related Ensembl:ENSG00000160446 AllianceGenome:HGNC:19159 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF400; DHHC-12 Summary Enables palmitoyltransferase activity. Involved in protein palmitoylation. Located in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 15.2), stomach (RPKM 13.4) and 25 other tissues See more Orthologs mouse all
ZDHHC13, Official Symbol ZDHHC13provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 13provided by HGNC Primary source HGNC:HGNC:18413 See related Ensembl:ENSG00000177054 MIM:612815; AllianceGenome:HGNC:18413 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIP14L; HIP3RP Summary Predicted to enable magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 18.5), urinary bladder (RPKM 11.0) and 24 other tissues See more Orthologs mouse all
ZDHHC14, Official Symbol ZDHHC14provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 14provided by HGNC Primary source HGNC:HGNC:20341 See related Ensembl:ENSG00000175048 MIM:619295; AllianceGenome:HGNC:20341 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 1CP Summary Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 2.5), endometrium (RPKM 2.3) and 24 other tissues See more Orthologs mouse all
ZDHHC15, Official Symbol ZDHHC15provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 15provided by HGNC Primary source HGNC:HGNC:20342 See related Ensembl:ENSG00000102383 MIM:300576; AllianceGenome:HGNC:20342 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRX91; DHHC15 Summary The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Broad expression in brain (RPKM 1.4), thyroid (RPKM 0.9) and 21 other tissues See more Orthologs mouse all
ZDHHC16, Official Symbol ZDHHC16provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 16provided by HGNC Primary source HGNC:HGNC:20714 See related Ensembl:ENSG00000171307 MIM:616750; AllianceGenome:HGNC:20714 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APH2; DHHC-16 Summary Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 10.0), lung (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
ZDHHC17, Official Symbol ZDHHC17provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 17provided by HGNC Primary source HGNC:HGNC:18412 See related Ensembl:ENSG00000186908 MIM:607799; AllianceGenome:HGNC:18412 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIP3; HYPH; HIP14; DHHC17; DHHC-17; HSPC294 Summary Enables identical protein binding activity and protein-cysteine S-palmitoyltransferase activity. Involved in lipoprotein transport and protein palmitoylation. Located in Golgi membrane; Golgi-associated vesicle membrane; and aggresome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 20.0), endometrium (RPKM 12.2) and 25 other tissues See more Orthologs mouse all
ZDHHC18, Official Symbol ZDHHC18provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 18provided by HGNC Primary source HGNC:HGNC:20712 See related Ensembl:ENSG00000204160 AllianceGenome:HGNC:20712 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC18; DHHC-18 Summary Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 36.8), appendix (RPKM 14.1) and 24 other tissues See more Orthologs mouse all
ZDHHC19, Official Symbol ZDHHC19provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 19provided by HGNC Primary source HGNC:HGNC:20713 See related Ensembl:ENSG00000163958 MIM:618671; AllianceGenome:HGNC:20713 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC19 Summary Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi membrane; endoplasmic reticulum; and perinucleolar compartment. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 16.0) See more Orthologs mouse all
ZDHHC2, Official Symbol ZDHHC2provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 2provided by HGNC Primary source HGNC:HGNC:18469 See related Ensembl:ENSG00000104219 MIM:618621; AllianceGenome:HGNC:18469 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC2; ZNF372 Summary Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of protein catabolic process; and regulation of protein localization to plasma membrane. Located in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 18.6), adrenal (RPKM 10.6) and 24 other tissues See more Orthologs mouse all
ZDHHC20, Official Symbol ZDHHC20provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 20provided by HGNC Primary source HGNC:HGNC:20749 See related Ensembl:ENSG00000180776 MIM:617972; AllianceGenome:HGNC:20749 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC20; DHHC-20; 4933421L13Rik Summary Enables protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in intracellular membrane-bounded organelle and plasma membrane. Is integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in stomach (RPKM 21.2), urinary bladder (RPKM 18.5) and 25 other tissues See more Orthologs mouse all
ZDHHC20-IT1, Official Symbol ZDHHC20-IT1provided by HGNC Official Full Name ZDHHC20 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:39900 See related AllianceGenome:HGNC:39900 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
ZDHHC20P2, Official Symbol ZDHHC20P2provided by HGNC Official Full Name zinc finger DHHC-type containing 20 pseudogene 2provided by HGNC Primary source HGNC:HGNC:33457 See related Ensembl:ENSG00000223702 AllianceGenome:HGNC:33457 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZDHHC20P3, Official Symbol ZDHHC20P3provided by HGNC Official Full Name zinc finger DHHC-type containing 20 pseudogene 3provided by HGNC Primary source HGNC:HGNC:39775 See related Ensembl:ENSG00000255460 AllianceGenome:HGNC:39775 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZDHHC21, Official Symbol ZDHHC21provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 21provided by HGNC Primary source HGNC:HGNC:20750 See related Ensembl:ENSG00000175893 MIM:614605; AllianceGenome:HGNC:20750 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DNZ1; DHHC21; DHHC-21; HSPC097 Summary Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 3.1), skin (RPKM 2.5) and 25 other tissues See more Orthologs mouse all
ZDHHC22, Official Symbol ZDHHC22provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 22provided by HGNC Primary source HGNC:HGNC:20106 See related Ensembl:ENSG00000177108 AllianceGenome:HGNC:20106 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf59 Summary Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 10.2) See more Orthologs mouse all
ZDHHC23, Official Symbol ZDHHC23provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 23provided by HGNC Primary source HGNC:HGNC:28654 See related Ensembl:ENSG00000184307 MIM:617334; AllianceGenome:HGNC:28654 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIDD; DHHC-23 Summary Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 5.9), colon (RPKM 3.9) and 24 other tissues See more Orthologs mouse all
ZDHHC24, Official Symbol ZDHHC24provided by HGNC Official Full Name zinc finger DHHC-type containing 24provided by HGNC Primary source HGNC:HGNC:27387 See related Ensembl:ENSG00000174165 AllianceGenome:HGNC:27387 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 1.8), kidney (RPKM 1.8) and 25 other tissues See more Orthologs mouse all
ZDHHC3, Official Symbol ZDHHC3provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 3provided by HGNC Primary source HGNC:HGNC:18470 See related Ensembl:ENSG00000163812 MIM:617150; AllianceGenome:HGNC:18470 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GODZ; DHHC3; DHHC-3; ZNF373 Summary Enables palmitoyltransferase activity. Involved in several processes, including TRAIL-activated apoptotic signaling pathway; protein localization to membrane; and protein localization to photoreceptor outer segment. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 9.5), skin (RPKM 8.8) and 25 other tissues See more Orthologs mouse all
ZDHHC4, Official Symbol ZDHHC4provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 4provided by HGNC Primary source HGNC:HGNC:18471 See related Ensembl:ENSG00000136247 AllianceGenome:HGNC:18471 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF374 Summary Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Located in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 21.7), testis (RPKM 20.1) and 25 other tissues See more Orthologs mouse all
ZDHHC4P1, Official Symbol ZDHHC4P1provided by HGNC Official Full Name zinc finger DHHC-type containing 4 pseudogene 1provided by HGNC Primary source HGNC:HGNC:39443 See related Ensembl:ENSG00000238025 AllianceGenome:HGNC:39443 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZDHHC5, Official Symbol ZDHHC5provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 5provided by HGNC Primary source HGNC:HGNC:18472 See related Ensembl:ENSG00000156599 MIM:614586; AllianceGenome:HGNC:18472 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC5; ZNF375 Summary Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in phagocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 30.1), thyroid (RPKM 23.7) and 25 other tissues See more Orthologs mouse all
ZDHHC6, Official Symbol ZDHHC6provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 6provided by HGNC Primary source HGNC:HGNC:19160 See related Ensembl:ENSG00000023041 MIM:618715; AllianceGenome:HGNC:19160 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC6; DHHC-6; ZNF376 Summary Enables palmitoyltransferase activity. Involved in positive regulation of mitochondrial fusion and protein palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in small intestine (RPKM 19.0), duodenum (RPKM 17.1) and 25 other tissues See more Orthologs mouse all
ZDHHC7, Official Symbol ZDHHC7provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 7provided by HGNC Primary source HGNC:HGNC:18459 See related Ensembl:ENSG00000153786 MIM:614604; AllianceGenome:HGNC:18459 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC7; SERZ1; SERZ-B; ZNF370 Summary Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; polarized epithelial cell differentiation; and regulation of signal transduction. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 20.6), lung (RPKM 20.0) and 25 other tissues See more Orthologs mouse all
ZDHHC8, Official Symbol ZDHHC8provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 8provided by HGNC Primary source HGNC:HGNC:18474 See related Ensembl:ENSG00000099904 MIM:608784; AllianceGenome:HGNC:18474 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHHC8; ZNF378; ZDHHCL1 Summary This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010] Expression Ubiquitous expression in fat (RPKM 6.8), spleen (RPKM 6.7) and 25 other tissues See more Orthologs mouse all
ZDHHC9, Official Symbol ZDHHC9provided by HGNC Official Full Name zinc finger DHHC-type palmitoyltransferase 9provided by HGNC Primary source HGNC:HGNC:18475 See related Ensembl:ENSG00000188706 MIM:300646; AllianceGenome:HGNC:18475 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGI89; DHHC9; MMSA1; MRXSR; MRXSZ; ZNF379; ZNF380; CXorf11; ZDHHC10 Summary This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010] Expression Ubiquitous expression in brain (RPKM 17.9), kidney (RPKM 10.5) and 25 other tissues See more Orthologs mouse all
ZEB1, Official Symbol ZEB1provided by HGNC Official Full Name zinc finger E-box binding homeobox 1provided by HGNC Primary source HGNC:HGNC:11642 See related Ensembl:ENSG00000148516 MIM:189909; AllianceGenome:HGNC:11642 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1 Summary This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010] Expression Ubiquitous expression in endometrium (RPKM 12.8), brain (RPKM 12.1) and 23 other tissues See more Orthologs mouse all
ZEB1-AS1, Official Symbol ZEB1-AS1provided by HGNC Official Full Name ZEB1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:42354 See related Ensembl:ENSG00000237036 MIM:616915; AllianceGenome:HGNC:42354 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in endometrium (RPKM 3.5), ovary (RPKM 3.4) and 25 other tissues See more
ZEB2, Official Symbol ZEB2provided by HGNC Official Full Name zinc finger E-box binding homeobox 2provided by HGNC Primary source HGNC:HGNC:14881 See related Ensembl:ENSG00000169554 MIM:605802; AllianceGenome:HGNC:14881 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1 Summary The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010] Expression Ubiquitous expression in brain (RPKM 13.4), appendix (RPKM 10.2) and 23 other tissues See more Orthologs mouse all
ZEB2-AS1, Official Symbol ZEB2-AS1provided by HGNC Official Full Name ZEB2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:37149 See related Ensembl:ENSG00000238057 AllianceGenome:HGNC:37149 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZEB2AS; ZEB2-AS; ZEB2NAT Summary This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in bone marrow (RPKM 12.1), brain (RPKM 10.2) and 23 other tissues See more Orthologs mouse all
ZEB2P1, Official Symbol ZEB2P1provided by HGNC Official Full Name zinc finger E-box binding homeobox 2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:33346 See related Ensembl:ENSG00000249506 AllianceGenome:HGNC:33346 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZEB1P1
ZER1, Official Symbol ZER1provided by HGNC Official Full Name zyg-11 related cell cycle regulatorprovided by HGNC Primary source HGNC:HGNC:30960 See related Ensembl:ENSG00000160445 MIM:617764; AllianceGenome:HGNC:30960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZYG; C9orf60; ZYG11BL Summary This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in brain (RPKM 20.9), testis (RPKM 20.5) and 25 other tissues See more Orthologs mouse all
ZFAND1, Official Symbol ZFAND1provided by HGNC Official Full Name zinc finger AN1-type containing 1provided by HGNC Primary source HGNC:HGNC:25858 See related Ensembl:ENSG00000104231 AllianceGenome:HGNC:25858 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables proteasome binding activity. Involved in cellular response to arsenite ion; positive regulation of intracellular protein transport; and stress granule disassembly. Located in cytoplasmic stress granule. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 23.7), ovary (RPKM 15.6) and 25 other tissues See more Orthologs mouse all
ZFAND2A, Official Symbol ZFAND2Aprovided by HGNC Official Full Name zinc finger AN1-type containing 2Aprovided by HGNC Primary source HGNC:HGNC:28073 See related Ensembl:ENSG00000178381 MIM:610699; AllianceGenome:HGNC:28073 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIRAP Summary Predicted to enable zinc ion binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein targeting to ER. Predicted to act upstream of or within cellular response to arsenic-containing substance and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome complex. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 5.6), liver (RPKM 4.6) and 25 other tissues See more Orthologs mouse all
ZFAND2B, Official Symbol ZFAND2Bprovided by HGNC Official Full Name zinc finger AN1-type containing 2Bprovided by HGNC Primary source HGNC:HGNC:25206 See related Ensembl:ENSG00000158552 MIM:613474; AllianceGenome:HGNC:25206 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIRAPL Summary This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in thyroid (RPKM 23.0), duodenum (RPKM 18.1) and 25 other tissues See more Orthologs mouse all
ZFAND3, Official Symbol ZFAND3provided by HGNC Official Full Name zinc finger AN1-type containing 3provided by HGNC Primary source HGNC:HGNC:18019 See related Ensembl:ENSG00000156639 MIM:607455; AllianceGenome:HGNC:18019 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TEX27 Summary Predicted to enable DNA binding activity and zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 29.7), thyroid (RPKM 22.9) and 25 other tissues See more Orthologs mouse all
ZFAND4, Official Symbol ZFAND4provided by HGNC Official Full Name zinc finger AN1-type containing 4provided by HGNC Primary source HGNC:HGNC:23504 See related Ensembl:ENSG00000172671 AllianceGenome:HGNC:23504 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANUBL1 Summary Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 26.4), lymph node (RPKM 2.8) and 9 other tissues See more Orthologs mouse all