psui3905/ncbi_genes_summary huggingface dataset:
MPV17L, Official Symbol MPV17Lprovided by HGNC Official Full Name MPV17 mitochondrial inner membrane protein likeprovided by HGNC Primary source HGNC:HGNC:26827 See related Ensembl:ENSG00000156968 MIM:618100; AllianceGenome:HGNC:26827 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M-LPH; MLPH1; MLPH2; M-LPH1; M-LPH2; MPV17L1 Summary Involved in negative regulation of hydrogen peroxide biosynthetic process; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; and reactive oxygen species metabolic process. Located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 1.8), duodenum (RPKM 1.5) and 20 other tissues See more Orthologs mouse all
MPV17L2, Official Symbol MPV17L2provided by HGNC Official Full Name MPV17 mitochondrial inner membrane protein like 2provided by HGNC Primary source HGNC:HGNC:28177 See related Ensembl:ENSG00000254858 MIM:616133; AllianceGenome:HGNC:28177 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FKSG24 Summary Involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrial inner membrane. Part of mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 6.2), thyroid (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
MPV17L2P1, Official Symbol MPV17L2P1provided by HGNC Official Full Name MPV17L2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:54962 See related Ensembl:ENSG00000234413 AllianceGenome:HGNC:54962 Gene type pseudo RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MPZ, Official Symbol MPZprovided by HGNC Official Full Name myelin protein zeroprovided by HGNC Primary source HGNC:HGNC:7225 See related Ensembl:ENSG00000158887 MIM:159440; AllianceGenome:HGNC:7225 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P0; CHM; DSS; MPP; CHN2; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB Summary This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015] Expression Broad expression in fat (RPKM 6.2), prostate (RPKM 4.2) and 20 other tissues See more Orthologs mouse all
MPZL1, Official Symbol MPZL1provided by HGNC Official Full Name myelin protein zero like 1provided by HGNC Primary source HGNC:HGNC:7226 See related Ensembl:ENSG00000197965 MIM:604376; AllianceGenome:HGNC:7226 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PZR; PZRa; PZRb; PZR1b; MPZL1b Summary Predicted to enable structural molecule activity. Predicted to be involved in cell-cell signaling and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within positive regulation of cell migration. Located in cell surface and focal adhesion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in gall bladder (RPKM 26.1), placenta (RPKM 23.6) and 25 other tissues See more Orthologs mouse all
MPZL2, Official Symbol MPZL2provided by HGNC Official Full Name myelin protein zero like 2provided by HGNC Primary source HGNC:HGNC:3496 See related Ensembl:ENSG00000149573 MIM:604873; AllianceGenome:HGNC:3496 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EVA; EVA1; DFNB111 Summary Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 92.3), urinary bladder (RPKM 53.8) and 14 other tissues See more Orthologs mouse all
MPZL3, Official Symbol MPZL3provided by HGNC Official Full Name myelin protein zero like 3provided by HGNC Primary source HGNC:HGNC:27279 See related Ensembl:ENSG00000160588 MIM:611707; AllianceGenome:HGNC:27279 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in cell adhesion. Predicted to act upstream of or within extracellular matrix organization and hair cycle. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in skin (RPKM 9.4), esophagus (RPKM 9.0) and 19 other tissues See more Orthologs mouse all
MR1, Official Symbol MR1provided by HGNC Official Full Name major histocompatibility complex, class I-relatedprovided by HGNC Primary source HGNC:HGNC:4975 See related Ensembl:ENSG00000153029 MIM:600764; AllianceGenome:HGNC:4975 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLALS Summary MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in urinary bladder (RPKM 6.3), thyroid (RPKM 5.6) and 24 other tissues See more Orthologs mouse all
MRAP, Official Symbol MRAPprovided by HGNC Official Full Name melanocortin 2 receptor accessory proteinprovided by HGNC Primary source HGNC:HGNC:1304 See related Ensembl:ENSG00000170262 MIM:609196; AllianceGenome:HGNC:1304 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B27; FALP; FGD2; GCCD2; MRAP1; C21orf61 Summary This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009] Expression Broad expression in fat (RPKM 19.3), adrenal (RPKM 18.8) and 20 other tissues See more Orthologs mouse all
MRAP-AS1, Official Symbol MRAP-AS1provided by HGNC Official Full Name MRAP antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40108 See related AllianceGenome:HGNC:40108 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in fat (RPKM 4.7), adrenal (RPKM 3.6) and 1 other tissue See more
MRAP2, Official Symbol MRAP2provided by HGNC Official Full Name melanocortin 2 receptor accessory protein 2provided by HGNC Primary source HGNC:HGNC:21232 See related Ensembl:ENSG00000135324 MIM:615410; AllianceGenome:HGNC:21232 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf117; bA51G5.2 Summary This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016] Expression Broad expression in brain (RPKM 4.0), adrenal (RPKM 2.1) and 20 other tissues See more Orthologs mouse all
MRAS, Official Symbol MRASprovided by HGNC Official Full Name muscle RAS oncogene homologprovided by HGNC Primary source HGNC:HGNC:7227 See related Ensembl:ENSG00000158186 MIM:608435; AllianceGenome:HGNC:7227 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NS11; M-RAs; RRAS3; R-RAS3 Summary This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in fat (RPKM 37.4), heart (RPKM 23.2) and 16 other tissues See more Orthologs mouse all
MRC1, Official Symbol MRC1provided by HGNC Official Full Name mannose receptor C-type 1provided by HGNC Primary source HGNC:HGNC:7228 See related Ensembl:ENSG00000260314 MIM:153618; AllianceGenome:HGNC:7228 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1 Summary The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] Annotation information Note: In the NCBI Build 37.2 reference assembly, MRC1 and MRC1L1 are duplicate genes in close proximity to each other on chromosome 10. In July 2010, the Genome Reference Consortium determined that the region contains a duplication error. Two of the clones on which MRC1L1 was based (AL928580, BX255924) will be removed from the reference assembly and only MRC1 will be present in the assembly. [13 Feb 2013] Expression Broad expression in lung (RPKM 50.7), spleen (RPKM 28.0) and 19 other tissues See more Orthologs mouse all
MRC2, Official Symbol MRC2provided by HGNC Official Full Name mannose receptor C type 2provided by HGNC Primary source HGNC:HGNC:16875 See related Ensembl:ENSG00000011028 MIM:612264; AllianceGenome:HGNC:16875 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD280; UPARAP; CLEC13E; ENDO180 Summary This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in gall bladder (RPKM 26.1), ovary (RPKM 24.7) and 24 other tissues See more Orthologs mouse all
MRE11, Official Symbol MRE11provided by HGNC Official Full Name MRE11 homolog, double strand break repair nucleaseprovided by HGNC Primary source HGNC:HGNC:7230 See related Ensembl:ENSG00000020922 MIM:600814; AllianceGenome:HGNC:7230 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATLD; HNGS1; MRE11A; MRE11B Summary This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in skin (RPKM 5.3), bone marrow (RPKM 4.6) and 25 other tissues See more Orthologs mouse all
MREG, Official Symbol MREGprovided by HGNC Official Full Name melanoregulinprovided by HGNC Primary source HGNC:HGNC:25478 See related Ensembl:ENSG00000118242 MIM:609207; AllianceGenome:HGNC:25478 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DSU; WDT2 Summary Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in melanocyte differentiation; melanosome transport; and phagosome maturation. Predicted to act upstream of or within developmental pigmentation. Predicted to be located in late endosome membrane and melanosome membrane. Predicted to be intrinsic component of organelle membrane. Predicted to be part of protein-containing complex. Predicted to be active in melanosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 7.4), skin (RPKM 5.3) and 22 other tissues See more Orthologs mouse all
MREGP1, Official Symbol MREGP1provided by HGNC Official Full Name melanoregulin pseudogene 1provided by HGNC Primary source HGNC:HGNC:50749 See related Ensembl:ENSG00000270395 AllianceGenome:HGNC:50749 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRFAP1, Official Symbol MRFAP1provided by HGNC Official Full Name Morf4 family associated protein 1provided by HGNC Primary source HGNC:HGNC:24549 See related Ensembl:ENSG00000179010 MIM:616905; AllianceGenome:HGNC:24549 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR1; PAM14 Summary This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in brain (RPKM 146.3), adrenal (RPKM 117.0) and 25 other tissues See more Orthologs all
MRFAP1L1, Official Symbol MRFAP1L1provided by HGNC Official Full Name Morf4 family associated protein 1 like 1provided by HGNC Primary source HGNC:HGNC:28796 See related Ensembl:ENSG00000178988 AllianceGenome:HGNC:28796 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP784 Summary Enables identical protein binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 49.2), endometrium (RPKM 34.4) and 25 other tissues See more Orthologs all
MRGBP, Official Symbol MRGBPprovided by HGNC Official Full Name MRG domain binding proteinprovided by HGNC Primary source HGNC:HGNC:15866 See related Ensembl:ENSG00000101189 MIM:611157; AllianceGenome:HGNC:15866 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Eaf7; URCC4; MRG15BP; C20orf20 Summary Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 23.2), ovary (RPKM 4.6) and 24 other tissues See more Orthologs mouse all
MRGPRD, Official Symbol MRGPRDprovided by HGNC Official Full Name MAS related GPR family member Dprovided by HGNC Primary source HGNC:HGNC:29626 See related Ensembl:ENSG00000172938 MIM:607231; AllianceGenome:HGNC:29626 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRGD; TGR7 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
MRGPRE, Official Symbol MRGPREprovided by HGNC Official Full Name MAS related GPR family member Eprovided by HGNC Primary source HGNC:HGNC:30694 See related Ensembl:ENSG00000184350 MIM:607232; AllianceGenome:HGNC:30694 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MGRF; MRGE; GPR167 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
MRGPRF, Official Symbol MRGPRFprovided by HGNC Official Full Name MAS related GPR family member Fprovided by HGNC Primary source HGNC:HGNC:24828 See related Ensembl:ENSG00000172935 MIM:607233; AllianceGenome:HGNC:24828 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RTA; MRGF; GPR140; GPR168 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in nuclear membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 20.4), prostate (RPKM 13.8) and 18 other tissues See more Orthologs mouse all
MRGPRF-AS1, Official Symbol MRGPRF-AS1provided by HGNC Official Full Name MRGPRF antisense RNA 1provided by HGNC Primary source HGNC:HGNC:51140 See related Ensembl:ENSG00000256508 AllianceGenome:HGNC:51140 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in endometrium (RPKM 1.2), prostate (RPKM 0.6) and 15 other tissues See more
MRGPRG, Official Symbol MRGPRGprovided by HGNC Official Full Name MAS related GPR family member Gprovided by HGNC Primary source HGNC:HGNC:24829 See related Ensembl:ENSG00000182170 MIM:607234; AllianceGenome:HGNC:24829 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRGG; GPR169 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
MRGPRG-AS1, Official Symbol MRGPRG-AS1provided by HGNC Official Full Name MRGPRG antisense RNA 1provided by HGNC Primary source HGNC:HGNC:26691 See related Ensembl:ENSG00000236301 AllianceGenome:HGNC:26691 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSD-40; C11orf36 Expression Restricted expression toward testis (RPKM 3.4) See more
MRGPRX1, Official Symbol MRGPRX1provided by HGNC Official Full Name MAS related GPR family member X1provided by HGNC Primary source HGNC:HGNC:17962 See related Ensembl:ENSG00000170255 MIM:607227; AllianceGenome:HGNC:17962 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR; MGRG2; MRGX1; SNSR4 Summary Enables transmembrane signaling receptor activity. Involved in cell surface receptor signaling pathway and response to chloroquine. Predicted to be located in cell surface. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
MRGPRX10P, Official Symbol MRGPRX10Pprovided by HGNC Official Full Name MAS related GPR family member X10, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54334 See related Ensembl:ENSG00000254720 AllianceGenome:HGNC:54334 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX11P, Official Symbol MRGPRX11Pprovided by HGNC Official Full Name MAS related GPR family member X11, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54335 See related Ensembl:ENSG00000254738 AllianceGenome:HGNC:54335 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX12P, Official Symbol MRGPRX12Pprovided by HGNC Official Full Name MAS related GPR family member X12, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54336 See related Ensembl:ENSG00000254857 AllianceGenome:HGNC:54336 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX13P, Official Symbol MRGPRX13Pprovided by HGNC Official Full Name MAS related GPR family member X13, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54337 See related Ensembl:ENSG00000254546 AllianceGenome:HGNC:54337 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX2, Official Symbol MRGPRX2provided by HGNC Official Full Name MAS related GPR family member X2provided by HGNC Primary source HGNC:HGNC:17983 See related Ensembl:ENSG00000183695 MIM:607228; AllianceGenome:HGNC:17983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MGRG3; MRGX2 Summary Enables G protein-coupled receptor activity and neuropeptide binding activity. Involved in mast cell degranulation and positive regulation of cytokinesis. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
MRGPRX3, Official Symbol MRGPRX3provided by HGNC Official Full Name MAS related GPR family member X3provided by HGNC Primary source HGNC:HGNC:17980 See related Ensembl:ENSG00000179826 MIM:607229; AllianceGenome:HGNC:17980 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR; MRGX3; SNSR1; SNSR2 Summary This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009] Expression Low expression observed in reference dataset See more Orthologs all
MRGPRX4, Official Symbol MRGPRX4provided by HGNC Official Full Name MAS related GPR family member X4provided by HGNC Primary source HGNC:HGNC:17617 See related Ensembl:ENSG00000179817 MIM:607230; AllianceGenome:HGNC:17617 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR; MRGX4; SNSR6 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
MRGPRX5P, Official Symbol MRGPRX5Pprovided by HGNC Official Full Name MAS related GPR family member X5, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54329 See related Ensembl:ENSG00000255536 AllianceGenome:HGNC:54329 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX6P, Official Symbol MRGPRX6Pprovided by HGNC Official Full Name MAS related GPR family member X6, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54330 See related Ensembl:ENSG00000254541 AllianceGenome:HGNC:54330 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX7P, Official Symbol MRGPRX7Pprovided by HGNC Official Full Name MAS related GPR family member X7, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54331 See related Ensembl:ENSG00000254529 AllianceGenome:HGNC:54331 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX8P, Official Symbol MRGPRX8Pprovided by HGNC Official Full Name MAS related GPR family member X8, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54332 See related Ensembl:ENSG00000276789 AllianceGenome:HGNC:54332 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRGPRX9P, Official Symbol MRGPRX9Pprovided by HGNC Official Full Name MAS related GPR family member X9, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54333 See related Ensembl:ENSG00000255424 AllianceGenome:HGNC:54333 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MRI1, Official Symbol MRI1provided by HGNC Official Full Name methylthioribose-1-phosphate isomerase 1provided by HGNC Primary source HGNC:HGNC:28469 See related Ensembl:ENSG00000037757 MIM:615105; AllianceGenome:HGNC:28469 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M1Pi; MRDI; MTNA; Ypr118w Summary This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in placenta (RPKM 6.8), skin (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
MRLN, Official Symbol MRLNprovided by HGNC Official Full Name myoregulinprovided by HGNC Primary source HGNC:HGNC:48649 See related Ensembl:ENSG00000227877 MIM:616246; AllianceGenome:HGNC:48649 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M1; MLN; MUSER1; Linc-RAM; LINC00948 Summary This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum Ca(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating Ca(2+) reuptake in the sarcoplasmic reticulum by inhibiting the Ca(2+) pump activity of SERCAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2015] Expression Biased expression in kidney (RPKM 2.5), prostate (RPKM 1.2) and 3 other tissues See more Orthologs mouse all
MRM1, Official Symbol MRM1provided by HGNC Official Full Name mitochondrial rRNA methyltransferase 1provided by HGNC Primary source HGNC:HGNC:26202 See related Ensembl:ENSG00000278619 MIM:618099; AllianceGenome:HGNC:26202 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables rRNA (guanosine-2'-O-)-methyltransferase activity. Predicted to be involved in rRNA 2'-O-methylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 1.2), lymph node (RPKM 1.0) and 25 other tissues See more Orthologs mouse all
MRM2, Official Symbol MRM2provided by HGNC Official Full Name mitochondrial rRNA methyltransferase 2provided by HGNC Primary source HGNC:HGNC:16352 See related Ensembl:ENSG00000122687 MIM:606906; AllianceGenome:HGNC:16352 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FJH1; FTSJ2; HEL97; RRMJ2; MTDPS17 Summary The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and it may be involved in the processing and modification of rRNA. This gene has been suggested to be involved in cell cycle control and DNA repair. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 11.5), appendix (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
MRM3, Official Symbol MRM3provided by HGNC Official Full Name mitochondrial rRNA methyltransferase 3provided by HGNC Primary source HGNC:HGNC:18485 See related Ensembl:ENSG00000171861 MIM:612600; AllianceGenome:HGNC:18485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RMTL1; RNMTL1 Summary Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in testis (RPKM 12.8), bone marrow (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
MRNIP, Official Symbol MRNIPprovided by HGNC Official Full Name MRN complex interacting proteinprovided by HGNC Primary source HGNC:HGNC:30817 See related Ensembl:ENSG00000161010 MIM:617154; AllianceGenome:HGNC:30817 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C5orf45 Summary Enables chromatin binding activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Located in nucleoplasm. Colocalizes with Mre11 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 41.9), lung (RPKM 28.1) and 25 other tissues See more Orthologs mouse all
MRO, Official Symbol MROprovided by HGNC Official Full Name maestroprovided by HGNC Primary source HGNC:HGNC:24121 See related Ensembl:ENSG00000134042 MIM:608080; AllianceGenome:HGNC:24121 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B29; C18orf3 Summary This gene is specifically transcribed in males before and after differentiation of testis, and the encoded protein may play an important role in a mammalian sex determination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 16.9), kidney (RPKM 11.1) and 9 other tissues See more Orthologs mouse all
MROCKI, Official Symbol MROCKIprovided by HGNC Official Full Name MARCKS cis regulating lncRNA promoter of cytokines and inflammationprovided by HGNC Primary source HGNC:HGNC:50323 See related Ensembl:ENSG00000227502 AllianceGenome:HGNC:50323 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ROCKI; LINC01268 Expression Broad expression in small intestine (RPKM 2.4), duodenum (RPKM 1.9) and 17 other tissues See more
MROH1, Official Symbol MROH1provided by HGNC Official Full Name maestro heat like repeat family member 1provided by HGNC Primary source HGNC:HGNC:26958 See related Ensembl:ENSG00000179832 AllianceGenome:HGNC:26958 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEATR7A Expression Ubiquitous expression in thyroid (RPKM 7.3), bone marrow (RPKM 4.8) and 25 other tissues See more Orthologs mouse all
MROH2A, Official Symbol MROH2Aprovided by HGNC Official Full Name maestro heat like repeat family member 2Aprovided by HGNC Primary source HGNC:HGNC:27936 See related Ensembl:ENSG00000185038 AllianceGenome:HGNC:27936 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEATR7B1 Summary This gene encodes a HEAT-domain-containing protein. The function of the encoded protein has not been characterized. [provided by RefSeq, Aug 2016] Expression Biased expression in thyroid (RPKM 1.0), testis (RPKM 1.0) and 3 other tissues See more Orthologs mouse all
MROH2B, Official Symbol MROH2Bprovided by HGNC Official Full Name maestro heat like repeat family member 2Bprovided by HGNC Primary source HGNC:HGNC:26857 See related Ensembl:ENSG00000171495 AllianceGenome:HGNC:26857 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPIF; HEATR7B2 Summary Predicted to be involved in protein kinase A signaling. Predicted to be located in acrosomal vesicle and sperm midpiece. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 23.2) See more Orthologs mouse all
MROH3P, Official Symbol MROH3Pprovided by HGNC Official Full Name maestro heat like repeat family member 3, pseudogeneprovided by HGNC Primary source HGNC:HGNC:33122 See related Ensembl:ENSG00000233217 AllianceGenome:HGNC:33122 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf81 Expression Low expression observed in reference dataset See more
MROH4P, Official Symbol MROH4Pprovided by HGNC Official Full Name maestro heat like repeat family member 4, pseudogeneprovided by HGNC Primary source HGNC:HGNC:44902 See related AllianceGenome:HGNC:44902 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
MROH5, Official Symbol MROH5provided by HGNC Official Full Name maestro heat like repeat family member 5 (gene/pseudogene)provided by HGNC Primary source HGNC:HGNC:42976 See related Ensembl:ENSG00000226807 AllianceGenome:HGNC:42976 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information Annotation category: suggests misassembly Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Expression Biased expression in testis (RPKM 3.5) and heart (RPKM 0.2) See more Orthologs mouse all
MROH6, Official Symbol MROH6provided by HGNC Official Full Name maestro heat like repeat family member 6provided by HGNC Primary source HGNC:HGNC:27814 See related Ensembl:ENSG00000204839 AllianceGenome:HGNC:27814 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8orf73 Expression Broad expression in bone marrow (RPKM 5.5), esophagus (RPKM 4.2) and 21 other tissues See more Orthologs mouse all
MROH7, Official Symbol MROH7provided by HGNC Official Full Name maestro heat like repeat family member 7provided by HGNC Primary source HGNC:HGNC:24802 See related Ensembl:ENSG00000184313 AllianceGenome:HGNC:24802 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEATR8; C1orf175 Summary Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 43.4), thyroid (RPKM 2.8) and 1 other tissue See more Orthologs mouse all
MROH8, Official Symbol MROH8provided by HGNC Official Full Name maestro heat like repeat family member 8provided by HGNC Primary source HGNC:HGNC:16125 See related Ensembl:ENSG00000101353 AllianceGenome:HGNC:16125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf131; C20orf132 Summary The protein encoded by this gene belongs to the maestro heat-like repeat family. The exact function of this gene is not known, however, in a genome-wide association study using hippocampal atrophy as a quantitative trait, this gene has been associated with Alzheimer's disease (PMID:19668339). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Annotation information Annotation category: suggests misassembly Expression Broad expression in testis (RPKM 12.2), kidney (RPKM 1.8) and 17 other tissues See more Orthologs mouse all
MROH9, Official Symbol MROH9provided by HGNC Official Full Name maestro heat like repeat family member 9provided by HGNC Primary source HGNC:HGNC:26287 See related Ensembl:ENSG00000117501 AllianceGenome:HGNC:26287 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARMC11; C1orf129 Expression Low expression observed in reference dataset See more Orthologs mouse all
MRPL1, Official Symbol MRPL1provided by HGNC Official Full Name mitochondrial ribosomal protein L1provided by HGNC Primary source HGNC:HGNC:14275 See related Ensembl:ENSG00000169288 MIM:611821; AllianceGenome:HGNC:14275 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L1MT; uL1m; BM022; MRP-L1 Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 8.5), heart (RPKM 8.4) and 25 other tissues See more Orthologs mouse all