psui3905/ncbi_genes_summary huggingface dataset:
ZG16, Official Symbol ZG16provided by HGNC Official Full Name zymogen granule protein 16provided by HGNC Primary source HGNC:HGNC:30961 See related Ensembl:ENSG00000174992 MIM:617311; AllianceGenome:HGNC:30961 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JCLN; JCLN1; ZG16A Summary Predicted to enable carbohydrate binding activity and peptidoglycan binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in Golgi lumen and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in colon (RPKM 333.1), small intestine (RPKM 82.8) and 1 other tissue See more Orthologs mouse all
ZG16B, Official Symbol ZG16Bprovided by HGNC Official Full Name zymogen granule protein 16Bprovided by HGNC Primary source HGNC:HGNC:30456 See related Ensembl:ENSG00000162078 MIM:620477; AllianceGenome:HGNC:30456 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EECP; PAUF; JCLN2; HRPE773; PRO1567 Summary Predicted to enable carbohydrate binding activity. Involved in retina homeostasis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward salivary gland (RPKM 15006.7) See more Orthologs all
ZGLP1, Official Symbol ZGLP1provided by HGNC Official Full Name zinc finger GATA like protein 1provided by HGNC Primary source HGNC:HGNC:37245 See related Ensembl:ENSG00000220201 MIM:611639; AllianceGenome:HGNC:37245 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLP1; GLP-1; GATAD3 Summary ZGLP1 encodes an evolutionary conserved transcriptional regulator with GATA-like zinc fingers. In females, it is expressed in embryonic germ cells and is essential for oogenic fate determination. It acts downstream of bone morphogenetic protein (BMP) and is involved in the regulation of genes involved in RNA processing, transcription and chromatin modification, retrotransposon regulation, meiotic cell cycle, and oocyte development. In males it is not required for the germ cell sex determination but is required by the spermatogonia for efficiently completing the meiotic prophase. [provided by RefSeq, Jul 2022] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s). Expression Ubiquitous expression in testis (RPKM 1.4), spleen (RPKM 0.9) and 25 other tissues See more Orthologs mouse all
ZGPAT, Official Symbol ZGPATprovided by HGNC Official Full Name zinc finger CCCH-type and G-patch domain containingprovided by HGNC Primary source HGNC:HGNC:15948 See related Ensembl:ENSG00000197114 MIM:619577; AllianceGenome:HGNC:15948 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847 Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in liver (RPKM 22.1), kidney (RPKM 17.5) and 25 other tissues See more Orthologs mouse all
ZGRF1, Official Symbol ZGRF1provided by HGNC Official Full Name zinc finger GRF-type containing 1provided by HGNC Primary source HGNC:HGNC:25654 See related Ensembl:ENSG00000138658 AllianceGenome:HGNC:25654 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C4orf21 Summary The encoded protein contains GRF zinc finger (zf-GRF) and transmembrane domains. GRF zinc fingers are found in a number of DNA-binding proteins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2017] Expression Broad expression in bone marrow (RPKM 3.0), testis (RPKM 2.5) and 24 other tissues See more Orthologs mouse all
ZHX1, Official Symbol ZHX1provided by HGNC Official Full Name zinc fingers and homeoboxes 1provided by HGNC Primary source HGNC:HGNC:12871 See related Ensembl:ENSG00000165156 MIM:604764; AllianceGenome:HGNC:12871 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in thyroid (RPKM 19.7), esophagus (RPKM 16.5) and 25 other tissues See more Orthologs mouse all
ZHX1-C8orf76, Official Symbol ZHX1-C8orf76provided by HGNC Official Full Name ZHX1-C8orf76 readthroughprovided by HGNC Primary source HGNC:HGNC:42975 See related Ensembl:ENSG00000259305 AllianceGenome:HGNC:42975 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring read-through transcription between the neighboring zinc fingers and homeoboxes 1 (ZHX1) and chromosome 8 open reading frame 76 (C8orf76) genes. The read-through transcript encodes a protein that shares sequence identity with the downstream gene, but it has a distinct N-terminus encoded by exon structure from the upstream gene. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in fat (RPKM 7.0), colon (RPKM 6.8) and 25 other tissues See more Orthologs all
ZHX2, Official Symbol ZHX2provided by HGNC Official Full Name zinc fingers and homeoboxes 2provided by HGNC Primary source HGNC:HGNC:18513 See related Ensembl:ENSG00000178764 MIM:609185; AllianceGenome:HGNC:18513 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAF; AFR1 Summary The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 12.8), lymph node (RPKM 11.9) and 25 other tissues See more Orthologs mouse all
ZHX3, Official Symbol ZHX3provided by HGNC Official Full Name zinc fingers and homeoboxes 3provided by HGNC Primary source HGNC:HGNC:15935 See related Ensembl:ENSG00000174306 MIM:609598; AllianceGenome:HGNC:15935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIX1 Summary This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 8.0), brain (RPKM 7.6) and 25 other tissues See more Orthologs mouse all
ZIC1, Official Symbol ZIC1provided by HGNC Official Full Name Zic family member 1provided by HGNC Primary source HGNC:HGNC:12872 See related Ensembl:ENSG00000152977 MIM:600470; AllianceGenome:HGNC:12872 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIC; CRS6; BAIDCS; ZNF201 Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 3.1), liver (RPKM 0.5) and 1 other tissue See more Orthologs mouse all
ZIC2, Official Symbol ZIC2provided by HGNC Official Full Name Zic family member 2provided by HGNC Primary source HGNC:HGNC:12873 See related Ensembl:ENSG00000043355 MIM:603073; AllianceGenome:HGNC:12873 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPE5 Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016] Expression Biased expression in brain (RPKM 3.1) and testis (RPKM 0.7) See more Orthologs mouse all
ZIC3, Official Symbol ZIC3provided by HGNC Official Full Name Zic family member 3provided by HGNC Primary source HGNC:HGNC:12874 See related Ensembl:ENSG00000156925 MIM:300265; AllianceGenome:HGNC:12874 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HTX; HTX1; ZNF203; VACTERLX Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZIC4, Official Symbol ZIC4provided by HGNC Official Full Name Zic family member 4provided by HGNC Primary source HGNC:HGNC:20393 See related Ensembl:ENSG00000174963 MIM:608948; AllianceGenome:HGNC:20393 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZIC5, Official Symbol ZIC5provided by HGNC Official Full Name Zic family member 5provided by HGNC Primary source HGNC:HGNC:20322 See related Ensembl:ENSG00000139800 MIM:617896; AllianceGenome:HGNC:20322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This gene is closely linked to a related family member on chromosome 13. [provided by RefSeq, Mar 2017] Expression Restricted expression toward testis (RPKM 2.7) See more Orthologs mouse all
ZIK1, Official Symbol ZIK1provided by HGNC Official Full Name zinc finger protein interacting with K protein 1provided by HGNC Primary source HGNC:HGNC:33104 See related Ensembl:ENSG00000171649 AllianceGenome:HGNC:33104 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF762 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 2.1), testis (RPKM 1.9) and 24 other tissues See more Orthologs all
ZIM2, Official Symbol ZIM2provided by HGNC Official Full Name zinc finger imprinted 2provided by HGNC Primary source HGNC:HGNC:12875 See related Ensembl:ENSG00000269699 AllianceGenome:HGNC:12875 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF656 Summary In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010] Expression Biased expression in ovary (RPKM 34.2), placenta (RPKM 19.3) and 4 other tissues See more Orthologs all
ZIM3, Official Symbol ZIM3provided by HGNC Official Full Name zinc finger imprinted 3provided by HGNC Primary source HGNC:HGNC:16366 See related Ensembl:ENSG00000141946 AllianceGenome:HGNC:16366 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF264; ZNF657 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
ZKSCAN1, Official Symbol ZKSCAN1provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 1provided by HGNC Primary source HGNC:HGNC:13101 See related Ensembl:ENSG00000106261 MIM:601260; AllianceGenome:HGNC:13101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX18; ZNF36; PHZ-37; ZNF139; ZSCAN33 Summary This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown to form stable and abundant circular RNAs. Elevated expression of this gene has been observed in gastric cancer and the encoded protein may stimulate migration and invasion of human gastric cancer cells. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in stomach (RPKM 13.7), skin (RPKM 12.9) and 25 other tissues See more Orthologs mouse all
ZKSCAN2, Official Symbol ZKSCAN2provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 2provided by HGNC Primary source HGNC:HGNC:25677 See related Ensembl:ENSG00000155592 AllianceGenome:HGNC:25677 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF694; ZSCAN31; ZSCAN34 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 3.7), ovary (RPKM 2.1) and 24 other tissues See more Orthologs mouse all
ZKSCAN2-DT, Official Symbol ZKSCAN2-DTprovided by HGNC Official Full Name ZKSCAN2 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:53912 See related Ensembl:ENSG00000274925 AllianceGenome:HGNC:53912 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZKSCAN3, Official Symbol ZKSCAN3provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 3provided by HGNC Primary source HGNC:HGNC:13853 See related Ensembl:ENSG00000189298 MIM:612791; AllianceGenome:HGNC:13853 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1. Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of autophagy; negative regulation of cellular senescence; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 1.5), ovary (RPKM 1.5) and 25 other tissues See more Orthologs all
ZKSCAN4, Official Symbol ZKSCAN4provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 4provided by HGNC Primary source HGNC:HGNC:13854 See related Ensembl:ENSG00000187626 MIM:611643; AllianceGenome:HGNC:13854 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF307; ZNF427; ZSCAN36; P1P373C6 Summary Enables identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.9), spleen (RPKM 2.1) and 24 other tissues See more Orthologs mouse all
ZKSCAN5, Official Symbol ZKSCAN5provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 5provided by HGNC Primary source HGNC:HGNC:12867 See related Ensembl:ENSG00000196652 MIM:611272; AllianceGenome:HGNC:12867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP95; ZFP-95; ZNF914; ZSCAN37 Summary This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in testis (RPKM 4.7), brain (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
ZKSCAN7, Official Symbol ZKSCAN7provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 7provided by HGNC Primary source HGNC:HGNC:12955 See related Ensembl:ENSG00000196345 AllianceGenome:HGNC:12955 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP; ZNF64; ZNF167; ZNF448; ZSCAN39 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 2.4), testis (RPKM 2.0) and 25 other tissues See more Orthologs mouse all
ZKSCAN7-AS1, Official Symbol ZKSCAN7-AS1provided by HGNC Official Full Name ZKSCAN7 ZNF cluster antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53964 See related AllianceGenome:HGNC:53964 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZKSCAN7P1, Official Symbol ZKSCAN7P1provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 7 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49867 See related Ensembl:ENSG00000256138 AllianceGenome:HGNC:49867 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZKSCAN8, Official Symbol ZKSCAN8provided by HGNC Official Full Name zinc finger with KRAB and SCAN domains 8provided by HGNC Primary source HGNC:HGNC:12983 See related Ensembl:ENSG00000198315 MIM:602240; AllianceGenome:HGNC:12983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LD5-1; ZNF192; ZSCAN40 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 9.3), ovary (RPKM 8.6) and 25 other tissues See more Orthologs mouse all
ZMAT1, Official Symbol ZMAT1provided by HGNC Official Full Name zinc finger matrin-type 1provided by HGNC Primary source HGNC:HGNC:29377 See related Ensembl:ENSG00000166432 MIM:301007; AllianceGenome:HGNC:29377 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in the nuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] Expression Ubiquitous expression in thyroid (RPKM 9.8), ovary (RPKM 6.5) and 25 other tissues See more Orthologs mouse all
ZMAT2, Official Symbol ZMAT2provided by HGNC Official Full Name zinc finger matrin-type 2provided by HGNC Primary source HGNC:HGNC:26433 See related Ensembl:ENSG00000146007 MIM:619930; AllianceGenome:HGNC:26433 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Snu23; Ptg-12 Summary Predicted to enable DNA binding activity and zinc ion binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 45.9), fat (RPKM 34.0) and 25 other tissues See more Orthologs mouse all
ZMAT3, Official Symbol ZMAT3provided by HGNC Official Full Name zinc finger matrin-type 3provided by HGNC Primary source HGNC:HGNC:29983 See related Ensembl:ENSG00000172667 MIM:606452; AllianceGenome:HGNC:29983 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WIG1; WIG-1; PAG608 Summary This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 11.2), gall bladder (RPKM 5.6) and 24 other tissues See more Orthologs mouse all
ZMAT4, Official Symbol ZMAT4provided by HGNC Official Full Name zinc finger matrin-type 4provided by HGNC Primary source HGNC:HGNC:25844 See related Ensembl:ENSG00000165061 AllianceGenome:HGNC:25844 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables identical protein binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in thyroid (RPKM 4.9) and brain (RPKM 1.9) See more Orthologs mouse all
ZMAT5, Official Symbol ZMAT5provided by HGNC Official Full Name zinc finger matrin-type 5provided by HGNC Primary source HGNC:HGNC:28046 See related Ensembl:ENSG00000100319 MIM:619741; AllianceGenome:HGNC:28046 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3H19; SNRNP20; U11/U12-20K Summary Predicted to enable zinc ion binding activity. Predicted to be involved in RNA splicing. Located in nucleoplasm. Part of U12-type spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 7.7), lung (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
ZMIZ1, Official Symbol ZMIZ1provided by HGNC Official Full Name zinc finger MIZ-type containing 1provided by HGNC Primary source HGNC:HGNC:16493 See related Ensembl:ENSG00000108175 MIM:607159; AllianceGenome:HGNC:16493 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIZ; RAI17; ZIMP10; NEDDFSA; TRAFIP10 Summary This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010] Expression Ubiquitous expression in ovary (RPKM 21.7), spleen (RPKM 21.6) and 25 other tissues See more Orthologs mouse all
ZMIZ1-AS1, Official Symbol ZMIZ1-AS1provided by HGNC Official Full Name ZMIZ1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:27433 See related Ensembl:ENSG00000224596 AllianceGenome:HGNC:27433 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 1.8), skin (RPKM 1.0) and 21 other tissues See more
ZMIZ2, Official Symbol ZMIZ2provided by HGNC Official Full Name zinc finger MIZ-type containing 2provided by HGNC Primary source HGNC:HGNC:22229 See related Ensembl:ENSG00000122515 MIM:611196; AllianceGenome:HGNC:22229 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET27; ZIMP7; hZIMP7; TRAFIP20 Summary ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] Expression Ubiquitous expression in spleen (RPKM 17.3), skin (RPKM 13.4) and 25 other tissues See more Orthologs mouse all
ZMPSTE24, Official Symbol ZMPSTE24provided by HGNC Official Full Name zinc metallopeptidase STE24provided by HGNC Primary source HGNC:HGNC:12877 See related Ensembl:ENSG00000084073 MIM:606480; AllianceGenome:HGNC:12877 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HGPS; PRO1; FACE1; RSDM1; STE24; FACE-1; Ste24p Summary This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 22.0), gall bladder (RPKM 20.0) and 25 other tissues See more Orthologs mouse all
ZMYM1, Official Symbol ZMYM1provided by HGNC Official Full Name zinc finger MYM-type containing 1provided by HGNC Primary source HGNC:HGNC:26253 See related Ensembl:ENSG00000197056 AllianceGenome:HGNC:26253 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYM Summary Predicted to enable protein dimerization activity and zinc ion binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 3.0), ovary (RPKM 2.8) and 25 other tissues See more Orthologs mouse all
ZMYM2, Official Symbol ZMYM2provided by HGNC Official Full Name zinc finger MYM-type containing 2provided by HGNC Primary source HGNC:HGNC:12989 See related Ensembl:ENSG00000121741 MIM:602221; AllianceGenome:HGNC:12989 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FIM; MYM; RAMP; SCLL; NECRC; ZNF198 Summary The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] Expression Ubiquitous expression in testis (RPKM 14.1), thyroid (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
ZMYM3, Official Symbol ZMYM3provided by HGNC Official Full Name zinc finger MYM-type containing 3provided by HGNC Primary source HGNC:HGNC:13054 See related Ensembl:ENSG00000147130 MIM:300061; AllianceGenome:HGNC:13054 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYM; XFIM; ZNF261; XLID112; DXS6673E; ZNF198L2 Summary This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010] Expression Ubiquitous expression in ovary (RPKM 15.3), testis (RPKM 11.9) and 25 other tissues See more Orthologs mouse all
ZMYM4, Official Symbol ZMYM4provided by HGNC Official Full Name zinc finger MYM-type containing 4provided by HGNC Primary source HGNC:HGNC:13055 See related Ensembl:ENSG00000146463 MIM:613568; AllianceGenome:HGNC:13055 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYM; CDIR; ZNF262; ZNF198L3 Summary Predicted to enable DNA binding activity. Involved in cytoskeleton organization and regulation of cell morphogenesis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 15.0), ovary (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
ZMYM4-AS1, Official Symbol ZMYM4-AS1provided by HGNC Official Full Name ZMYM4 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40624 See related Ensembl:ENSG00000227409 AllianceGenome:HGNC:40624 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZMYM5, Official Symbol ZMYM5provided by HGNC Official Full Name zinc finger MYM-type containing 5provided by HGNC Primary source HGNC:HGNC:13029 See related Ensembl:ENSG00000132950 MIM:616443; AllianceGenome:HGNC:13029 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYM; ZNF237; HSPC050; ZNF198L1 Summary Predicted to enable zinc ion binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 10.0), gall bladder (RPKM 4.8) and 25 other tissues See more Orthologs all
ZMYM6, Official Symbol ZMYM6provided by HGNC Official Full Name zinc finger MYM-type containing 6provided by HGNC Primary source HGNC:HGNC:13050 See related Ensembl:ENSG00000163867 MIM:613567; AllianceGenome:HGNC:13050 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYM; ZBED7; ZNF258; Buster2; ZNF198L4 Summary Predicted to enable DNA binding activity. Involved in cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 6.2), bone marrow (RPKM 5.8) and 25 other tissues See more Orthologs mouse all
ZMYND10, Official Symbol ZMYND10provided by HGNC Official Full Name zinc finger MYND-type containing 10provided by HGNC Primary source HGNC:HGNC:19412 See related Ensembl:ENSG00000004838 MIM:607070; AllianceGenome:HGNC:19412 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BLU; FLU; CILD22; DNAAF7 Summary This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Expression Restricted expression toward testis (RPKM 91.8) See more Orthologs mouse all
ZMYND11, Official Symbol ZMYND11provided by HGNC Official Full Name zinc finger MYND-type containing 11provided by HGNC Primary source HGNC:HGNC:16966 See related Ensembl:ENSG00000015171 MIM:608668; AllianceGenome:HGNC:16966 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BS69; BRAM1; MRD30 Summary The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues See more Orthologs mouse all
ZMYND12, Official Symbol ZMYND12provided by HGNC Official Full Name zinc finger MYND-type containing 12provided by HGNC Primary source HGNC:HGNC:21192 See related Ensembl:ENSG00000066185 AllianceGenome:HGNC:21192 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 21.0), kidney (RPKM 3.5) and 7 other tissues See more Orthologs mouse all
ZMYND15, Official Symbol ZMYND15provided by HGNC Official Full Name zinc finger MYND-type containing 15provided by HGNC Primary source HGNC:HGNC:20997 See related Ensembl:ENSG00000141497 MIM:614312; AllianceGenome:HGNC:20997 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPGF14 Summary This gene encodes a MYND-containing zinc-binding protein with a nuclear localization sequence. A similar gene in mice has been shown to act as a testis-specific transcriptional repressor by recruiting histone deacetylase enzymes to regulate spatiotemporal expression of many haploid genes. This protein may play an important role in spermatogenesis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012] Expression Biased expression in testis (RPKM 15.6), lung (RPKM 3.5) and 10 other tissues See more Orthologs mouse all
ZMYND19, Official Symbol ZMYND19provided by HGNC Official Full Name zinc finger MYND-type containing 19provided by HGNC Primary source HGNC:HGNC:21146 See related Ensembl:ENSG00000165724 MIM:611424; AllianceGenome:HGNC:21146 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIZIP Summary ZMYND19 is a MYND zinc finger domain-containing protein that binds to the C terminus of melanin-concentrating hormone receptor-1 (MCHR1; MIM 601751) (Bachner et al., 2002 [PubMed 12208518]), and to the N termini of alpha-tubulin (TUBA1; MIM 191110), and beta-tubulin (TUBB; MIM 191130) (Francke et al., 2005 [PubMed 16039987]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 12.2), skin (RPKM 4.6) and 25 other tissues See more Orthologs mouse all
ZMYND8, Official Symbol ZMYND8provided by HGNC Official Full Name zinc finger MYND-type containing 8provided by HGNC Primary source HGNC:HGNC:9397 See related Ensembl:ENSG00000101040 MIM:615713; AllianceGenome:HGNC:9397 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RACK7; PRKCBP1; PRO2893 Summary The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 6.9), testis (RPKM 4.9) and 25 other tissues See more Orthologs mouse all
ZNF10, Official Symbol ZNF10provided by HGNC Official Full Name zinc finger protein 10provided by HGNC Primary source HGNC:HGNC:12879 See related Ensembl:ENSG00000256223 MIM:194538; AllianceGenome:HGNC:12879 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX1 Summary The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 6.7), thyroid (RPKM 5.7) and 25 other tissues See more Orthologs all
ZNF100, Official Symbol ZNF100provided by HGNC Official Full Name zinc finger protein 100provided by HGNC Primary source HGNC:HGNC:12880 See related Ensembl:ENSG00000197020 MIM:603982; AllianceGenome:HGNC:12880 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 4.3), lymph node (RPKM 3.3) and 25 other tissues See more Orthologs all
ZNF101, Official Symbol ZNF101provided by HGNC Official Full Name zinc finger protein 101provided by HGNC Primary source HGNC:HGNC:12881 See related Ensembl:ENSG00000181896 MIM:603983; AllianceGenome:HGNC:12881 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HZF12 Summary Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Nov 2010] Expression Broad expression in lymph node (RPKM 7.9), appendix (RPKM 4.5) and 22 other tissues See more Orthologs all
ZNF101P2, Official Symbol ZNF101P2provided by HGNC Official Full Name zinc finger protein 101 pseudogene 2provided by HGNC Primary source HGNC:HGNC:44942 See related Ensembl:ENSG00000234473 AllianceGenome:HGNC:44942 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo