psui3905/ncbi_genes_summary huggingface dataset:
ZBTB3, Official Symbol ZBTB3provided by HGNC Official Full Name zinc finger and BTB domain containing 3provided by HGNC Primary source HGNC:HGNC:22918 See related Ensembl:ENSG00000185670 AllianceGenome:HGNC:22918 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 1.5), skin (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
ZBTB32, Official Symbol ZBTB32provided by HGNC Official Full Name zinc finger and BTB domain containing 32provided by HGNC Primary source HGNC:HGNC:16763 See related Ensembl:ENSG00000011590 MIM:605859; AllianceGenome:HGNC:16763 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Rog; FAXF; FAZF; TZFP; mynn; ZNF538 Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 13.5), lymph node (RPKM 1.5) and 2 other tissues See more Orthologs mouse all
ZBTB33, Official Symbol ZBTB33provided by HGNC Official Full Name zinc finger and BTB domain containing 33provided by HGNC Primary source HGNC:HGNC:16682 See related Ensembl:ENSG00000177485 MIM:300329; AllianceGenome:HGNC:16682 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF348; ZNF-kaiso Summary This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-&#945;2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010] Expression Ubiquitous expression in skin (RPKM 10.2), bone marrow (RPKM 8.2) and 25 other tissues See more Orthologs mouse all
ZBTB34, Official Symbol ZBTB34provided by HGNC Official Full Name zinc finger and BTB domain containing 34provided by HGNC Primary source HGNC:HGNC:31446 See related Ensembl:ENSG00000177125 MIM:611692; AllianceGenome:HGNC:31446 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF918 Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 6.2), placenta (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
ZBTB37, Official Symbol ZBTB37provided by HGNC Official Full Name zinc finger and BTB domain containing 37provided by HGNC Primary source HGNC:HGNC:28365 See related Ensembl:ENSG00000185278 AllianceGenome:HGNC:28365 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF908; D430004I08Rik Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 2.8), bone marrow (RPKM 1.4) and 24 other tissues See more Orthologs mouse all
ZBTB38, Official Symbol ZBTB38provided by HGNC Official Full Name zinc finger and BTB domain containing 38provided by HGNC Primary source HGNC:HGNC:26636 See related Ensembl:ENSG00000177311 MIM:612218; AllianceGenome:HGNC:26636 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CIBZ; ZNF921; PPP1R171 Summary The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010] Expression Ubiquitous expression in endometrium (RPKM 20.7), gall bladder (RPKM 13.0) and 24 other tissues See more Orthologs mouse all
ZBTB39, Official Symbol ZBTB39provided by HGNC Official Full Name zinc finger and BTB domain containing 39provided by HGNC Primary source HGNC:HGNC:29014 See related Ensembl:ENSG00000166860 MIM:619384; AllianceGenome:HGNC:29014 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF922 Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 5.1), ovary (RPKM 2.2) and 25 other tissues See more Orthologs mouse all
ZBTB4, Official Symbol ZBTB4provided by HGNC Official Full Name zinc finger and BTB domain containing 4provided by HGNC Primary source HGNC:HGNC:23847 See related Ensembl:ENSG00000174282 MIM:612308; AllianceGenome:HGNC:23847 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF903; KAISO-L1 Summary Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; methyl-CpNpG binding activity; and sequence-specific DNA binding activity. Involved in cellular response to DNA damage stimulus and negative regulation of transcription by RNA polymerase II. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 24.8), thyroid (RPKM 20.6) and 25 other tissues See more Orthologs mouse all
ZBTB40, Official Symbol ZBTB40provided by HGNC Official Full Name zinc finger and BTB domain containing 40provided by HGNC Primary source HGNC:HGNC:29045 See related Ensembl:ENSG00000184677 MIM:612106; AllianceGenome:HGNC:29045 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF923 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to DNA damage stimulus. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 6.6), spleen (RPKM 6.6) and 25 other tissues See more Orthologs mouse all
ZBTB40-IT1, Official Symbol ZBTB40-IT1provided by HGNC Official Full Name ZBTB40 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41493 See related MIM:618485; AllianceGenome:HGNC:41493 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
ZBTB41, Official Symbol ZBTB41provided by HGNC Official Full Name zinc finger and BTB domain containing 41provided by HGNC Primary source HGNC:HGNC:24819 See related Ensembl:ENSG00000177888 AllianceGenome:HGNC:24819 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRBZ1; ZNF924 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 4.8), brain (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
ZBTB42, Official Symbol ZBTB42provided by HGNC Official Full Name zinc finger and BTB domain containing 42provided by HGNC Primary source HGNC:HGNC:32550 See related Ensembl:ENSG00000179627 MIM:613915; AllianceGenome:HGNC:32550 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCCS6; ZNF925 Summary The protein encoded by this gene is a member of the C2H2 zinc finger protein family. This protein is predicted to have a pox virus and zinc finger (POZ) domain at the N-terminus and four zinc finger domains at the C-terminus. In human and mouse, the protein localizes to the nuclei of skeletal muscle cells. Knockdown of this gene in zebrafish results in abnormal skeletal muscle development and myofibrillar disorganization. A novel homozygous variant of the human gene has been associated with lethal congenital contracture syndrome, an autosomal recessive disorder that results in muscle wasting. [provided by RefSeq, Mar 2015] Expression Ubiquitous expression in prostate (RPKM 4.4), lung (RPKM 3.3) and 24 other tissues See more Orthologs mouse all
ZBTB43, Official Symbol ZBTB43provided by HGNC Official Full Name zinc finger and BTB domain containing 43provided by HGNC Primary source HGNC:HGNC:17908 See related Ensembl:ENSG00000169155 MIM:618676; AllianceGenome:HGNC:17908 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF-X; ZBTB22B; ZNF297B Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 18.2), testis (RPKM 10.2) and 24 other tissues See more Orthologs mouse all
ZBTB44, Official Symbol ZBTB44provided by HGNC Official Full Name zinc finger and BTB domain containing 44provided by HGNC Primary source HGNC:HGNC:25001 See related Ensembl:ENSG00000196323 AllianceGenome:HGNC:25001 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTBD15; ZNF851; HSPC063 Summary Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 15.0), kidney (RPKM 11.4) and 25 other tissues See more Orthologs mouse all
ZBTB44-DT, Official Symbol ZBTB44-DTprovided by HGNC Official Full Name ZBTB44 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:54265 See related Ensembl:ENSG00000175773 AllianceGenome:HGNC:54265 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 1.1), kidney (RPKM 0.2) and 5 other tissues See more
ZBTB45, Official Symbol ZBTB45provided by HGNC Official Full Name zinc finger and BTB domain containing 45provided by HGNC Primary source HGNC:HGNC:23715 See related Ensembl:ENSG00000119574 AllianceGenome:HGNC:23715 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF499 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 3.6), spleen (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
ZBTB45P1, Official Symbol ZBTB45P1provided by HGNC Official Full Name zinc finger and BTB domain containing 45 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49227 See related AllianceGenome:HGNC:49227 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZBTB46, Official Symbol ZBTB46provided by HGNC Official Full Name zinc finger and BTB domain containing 46provided by HGNC Primary source HGNC:HGNC:16094 See related Ensembl:ENSG00000130584 MIM:614639; AllianceGenome:HGNC:16094 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BZEL; BTBD4; RINZF; ZNF340; dJ583P15.7; dJ583P15.8 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of leukocyte differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 6.8), spleen (RPKM 5.8) and 25 other tissues See more Orthologs mouse all
ZBTB47, Official Symbol ZBTB47provided by HGNC Official Full Name zinc finger and BTB domain containing 47provided by HGNC Primary source HGNC:HGNC:26955 See related Ensembl:ENSG00000114853 MIM:619969; AllianceGenome:HGNC:26955 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF651 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in heart (RPKM 22.4), brain (RPKM 14.9) and 22 other tissues See more Orthologs mouse all
ZBTB48, Official Symbol ZBTB48provided by HGNC Official Full Name zinc finger and BTB domain containing 48provided by HGNC Primary source HGNC:HGNC:4930 See related Ensembl:ENSG00000204859 MIM:165270; AllianceGenome:HGNC:4930 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HKR3; TZAP; ZNF855; pp9964 Summary Enables double-stranded telomeric DNA binding activity; identical protein binding activity; and transcription cis-regulatory region binding activity. Involved in positive regulation of transcription, DNA-templated and telomere maintenance via telomere lengthening. Located in chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 9.3), spleen (RPKM 7.4) and 25 other tissues See more Orthologs mouse all
ZBTB49, Official Symbol ZBTB49provided by HGNC Official Full Name zinc finger and BTB domain containing 49provided by HGNC Primary source HGNC:HGNC:19883 See related Ensembl:ENSG00000168826 MIM:616238; AllianceGenome:HGNC:19883 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF509 Summary Enables DNA-binding transcription factor binding activity; sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Located in cytosol; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 3.0), spleen (RPKM 2.4) and 25 other tissues See more Orthologs mouse all
ZBTB5, Official Symbol ZBTB5provided by HGNC Official Full Name zinc finger and BTB domain containing 5provided by HGNC Primary source HGNC:HGNC:23836 See related Ensembl:ENSG00000168795 MIM:616590; AllianceGenome:HGNC:23836 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.3), esophagus (RPKM 6.3) and 25 other tissues See more Orthologs mouse all
ZBTB6, Official Symbol ZBTB6provided by HGNC Official Full Name zinc finger and BTB domain containing 6provided by HGNC Primary source HGNC:HGNC:16764 See related Ensembl:ENSG00000186130 MIM:605976; AllianceGenome:HGNC:16764 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZID; ZNF482 Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 5.7), thyroid (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
ZBTB7A, Official Symbol ZBTB7Aprovided by HGNC Official Full Name zinc finger and BTB domain containing 7Aprovided by HGNC Primary source HGNC:HGNC:18078 See related Ensembl:ENSG00000178951 MIM:605878; AllianceGenome:HGNC:18078 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LRF; FBI1; FBI-1; TIP21; ZBTB7; MNDLFH; ZNF857A; pokemon Summary Enables several functions, including SMAD binding activity; androgen receptor binding activity; and transcription corepressor binding activity. Involved in several processes, including erythrocyte maturation; negative regulation of signal transduction; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. Colocalizes with DNA-dependent protein kinase complex and NuRD complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 8.0), stomach (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
ZBTB7B, Official Symbol ZBTB7Bprovided by HGNC Official Full Name zinc finger and BTB domain containing 7Bprovided by HGNC Primary source HGNC:HGNC:18668 See related Ensembl:ENSG00000160685 MIM:607646; AllianceGenome:HGNC:18668 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as vGAF; CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B Summary This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] Expression Broad expression in skin (RPKM 39.5), duodenum (RPKM 31.2) and 25 other tissues See more Orthologs mouse all
ZBTB7C, Official Symbol ZBTB7Cprovided by HGNC Official Full Name zinc finger and BTB domain containing 7Cprovided by HGNC Primary source HGNC:HGNC:31700 See related Ensembl:ENSG00000184828 MIM:616591; AllianceGenome:HGNC:31700 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APM1; APM-1; ZBTB36; ZNF857C Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of cell population proliferation. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 8.6), skin (RPKM 4.3) and 18 other tissues See more Orthologs mouse all
ZBTB8A, Official Symbol ZBTB8Aprovided by HGNC Official Full Name zinc finger and BTB domain containing 8Aprovided by HGNC Primary source HGNC:HGNC:24172 See related Ensembl:ENSG00000160062 MIM:618742; AllianceGenome:HGNC:24172 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BOZF1; ZBTB8; ZNF916A Summary Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 3.1), thyroid (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
ZBTB8B, Official Symbol ZBTB8Bprovided by HGNC Official Full Name zinc finger and BTB domain containing 8Bprovided by HGNC Primary source HGNC:HGNC:37057 See related Ensembl:ENSG00000273274 AllianceGenome:HGNC:37057 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF916B Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZBTB8OS, Official Symbol ZBTB8OSprovided by HGNC Official Full Name zinc finger and BTB domain containing 8 opposite strandprovided by HGNC Primary source HGNC:HGNC:24094 See related Ensembl:ENSG00000176261 MIM:615891; AllianceGenome:HGNC:24094 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARCH; ARCH2 Summary Predicted to enable metal ion binding activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 4.0), lymph node (RPKM 3.5) and 25 other tissues See more Orthologs mouse all
ZBTB9, Official Symbol ZBTB9provided by HGNC Official Full Name zinc finger and BTB domain containing 9provided by HGNC Primary source HGNC:HGNC:28323 See related Ensembl:ENSG00000213588 AllianceGenome:HGNC:28323 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF919 Summary Enables identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.2), ovary (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
ZC2HC1A, Official Symbol ZC2HC1Aprovided by HGNC Official Full Name zinc finger C2HC-type containing 1Aprovided by HGNC Primary source HGNC:HGNC:24277 See related Ensembl:ENSG00000104427 AllianceGenome:HGNC:24277 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGI-62; C8orf70; FAM164A Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 5.6), thyroid (RPKM 3.9) and 22 other tissues See more Orthologs mouse all
ZC2HC1B, Official Symbol ZC2HC1Bprovided by HGNC Official Full Name zinc finger C2HC-type containing 1Bprovided by HGNC Primary source HGNC:HGNC:21174 See related Ensembl:ENSG00000118491 AllianceGenome:HGNC:21174 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf94; FAM164B; dJ468K18.5 Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 7.2) See more Orthologs mouse all
ZC2HC1C, Official Symbol ZC2HC1Cprovided by HGNC Official Full Name zinc finger C2HC-type containing 1Cprovided by HGNC Primary source HGNC:HGNC:20354 See related Ensembl:ENSG00000119703 AllianceGenome:HGNC:20354 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM164C; C14orf140 Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 18.3), thyroid (RPKM 2.1) and 2 other tissues See more Orthologs mouse all
ZC3H10, Official Symbol ZC3H10provided by HGNC Official Full Name zinc finger CCCH-type containing 10provided by HGNC Primary source HGNC:HGNC:25893 See related Ensembl:ENSG00000135482 AllianceGenome:HGNC:25893 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3HDC10 Summary Enables miRNA binding activity. Involved in negative regulation of production of miRNAs involved in gene silencing by miRNA and posttranscriptional regulation of gene expression. Predicted to be active in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 6.2), ovary (RPKM 4.7) and 25 other tissues See more Orthologs mouse all
ZC3H11A, Official Symbol ZC3H11Aprovided by HGNC Official Full Name zinc finger CCCH-type containing 11Aprovided by HGNC Primary source HGNC:HGNC:29093 See related Ensembl:ENSG00000058673 MIM:613513; AllianceGenome:HGNC:29093 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3HDC11A Summary Enables RNA binding activity. Involved in poly(A)+ mRNA export from nucleus. Colocalizes with transcription export complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 33.1), lymph node (RPKM 28.6) and 25 other tissues See more Orthologs mouse all
ZC3H11B, Official Symbol ZC3H11Bprovided by HGNC Official Full Name zinc finger CCCH-type containing 11Bprovided by HGNC Primary source HGNC:HGNC:25659 See related Ensembl:ENSG00000215817 AllianceGenome:HGNC:25659 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3HDC11B Summary Predicted to enable mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
ZC3H12A, Official Symbol ZC3H12Aprovided by HGNC Official Full Name zinc finger CCCH-type containing 12Aprovided by HGNC Primary source HGNC:HGNC:26259 See related Ensembl:ENSG00000163874 MIM:610562; AllianceGenome:HGNC:26259 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Reg1; MCPIP; MCPIP1; MCPIP-1; dJ423B22.1 Summary ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008] Expression Broad expression in bone marrow (RPKM 42.1), urinary bladder (RPKM 18.8) and 17 other tissues See more Orthologs mouse all
ZC3H12B, Official Symbol ZC3H12Bprovided by HGNC Official Full Name zinc finger CCCH-type containing 12Bprovided by HGNC Primary source HGNC:HGNC:17407 See related Ensembl:ENSG00000102053 MIM:300889; AllianceGenome:HGNC:17407 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCPIP2; CXorf32 Summary The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease. [provided by RefSeq, May 2010] Expression Ubiquitous expression in brain (RPKM 1.1), ovary (RPKM 0.5) and 22 other tissues See more Orthologs mouse all
ZC3H12C, Official Symbol ZC3H12Cprovided by HGNC Official Full Name zinc finger CCCH-type containing 12Cprovided by HGNC Primary source HGNC:HGNC:29362 See related Ensembl:ENSG00000149289 MIM:615001; AllianceGenome:HGNC:29362 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCPIP3 Summary Predicted to enable endoribonuclease activity and mRNA binding activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.1), colon (RPKM 2.2) and 25 other tissues See more Orthologs mouse all
ZC3H12D, Official Symbol ZC3H12Dprovided by HGNC Official Full Name zinc finger CCCH-type containing 12Dprovided by HGNC Primary source HGNC:HGNC:21175 See related Ensembl:ENSG00000178199 MIM:611106; AllianceGenome:HGNC:21175 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TFL; p34; MCPIP4; C6orf95; dJ281H8.1 Summary Predicted to enable endoribonuclease activity and mRNA binding activity. Involved in negative regulation of G1/S transition of mitotic cell cycle and negative regulation of cell growth. Located in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lymph node (RPKM 4.6), appendix (RPKM 3.5) and 11 other tissues See more Orthologs mouse all
ZC3H13, Official Symbol ZC3H13provided by HGNC Official Full Name zinc finger CCCH-type containing 13provided by HGNC Primary source HGNC:HGNC:20368 See related Ensembl:ENSG00000123200 MIM:616453; AllianceGenome:HGNC:20368 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Xio; KIAA0853 Summary Enables RNA binding activity. Involved in mRNA methylation. Located in nuclear speck. Part of RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 10.7), thyroid (RPKM 9.2) and 25 other tissues See more Orthologs mouse all
ZC3H14, Official Symbol ZC3H14provided by HGNC Official Full Name zinc finger CCCH-type containing 14provided by HGNC Primary source HGNC:HGNC:20509 See related Ensembl:ENSG00000100722 MIM:613279; AllianceGenome:HGNC:20509 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SUT2; MRT56; UKp68; MSUT-2; NY-REN-37 Summary The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation. [provided by RefSeq, May 2016] Expression Broad expression in testis (RPKM 19.6), thyroid (RPKM 8.3) and 25 other tissues See more Orthologs mouse all
ZC3H15, Official Symbol ZC3H15provided by HGNC Official Full Name zinc finger CCCH-type containing 15provided by HGNC Primary source HGNC:HGNC:29528 See related Ensembl:ENSG00000065548 MIM:619704; AllianceGenome:HGNC:29528 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFRP1; HT010; LEREPO4; MSTP012 Summary Enables RNA binding activity and cadherin binding activity. Involved in positive regulation of GTPase activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 44.3), brain (RPKM 30.6) and 25 other tissues See more Orthologs mouse all
ZC3H18, Official Symbol ZC3H18provided by HGNC Official Full Name zinc finger CCCH-type containing 18provided by HGNC Primary source HGNC:HGNC:25091 See related Ensembl:ENSG00000158545 AllianceGenome:HGNC:25091 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NHN1 Summary Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in RNA destabilization. Located in nuclear speck. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 13.0), spleen (RPKM 10.3) and 25 other tissues See more Orthologs mouse all
ZC3H3, Official Symbol ZC3H3provided by HGNC Official Full Name zinc finger CCCH-type containing 3provided by HGNC Primary source HGNC:HGNC:28972 See related Ensembl:ENSG00000014164 MIM:618640; AllianceGenome:HGNC:28972 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMICL; ZC3HDC3 Summary Predicted to enable SMAD binding activity. Involved in regulation of mRNA polyadenylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 6.1), testis (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
ZC3H4, Official Symbol ZC3H4provided by HGNC Official Full Name zinc finger CCCH-type containing 4provided by HGNC Primary source HGNC:HGNC:17808 See related Ensembl:ENSG00000130749 MIM:619498; AllianceGenome:HGNC:17808 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C19orf7 Summary This gene encodes a member of a family of CCCH (C-x8-C-x5-C-x3-H type) zinc finger domain-containing proteins. These zinc finger domains, which coordinate zinc finger binding and are characterized by three cysteine residues and one histidine residue, are nucleic acid-binding. Other family members are known to function in post-transcriptional regulation. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in spleen (RPKM 3.8), ovary (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
ZC3H6, Official Symbol ZC3H6provided by HGNC Official Full Name zinc finger CCCH-type containing 6provided by HGNC Primary source HGNC:HGNC:24762 See related Ensembl:ENSG00000188177 AllianceGenome:HGNC:24762 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3HDC6 Summary Predicted to enable RNA binding activity and metal ion binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 3.2), thyroid (RPKM 2.4) and 25 other tissues See more Orthologs mouse all
ZC3H7A, Official Symbol ZC3H7Aprovided by HGNC Official Full Name zinc finger CCCH-type containing 7Aprovided by HGNC Primary source HGNC:HGNC:30959 See related Ensembl:ENSG00000122299 MIM:619819; AllianceGenome:HGNC:30959 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZC3H7; HSPC055; ZC3HDC7 Summary Enables miRNA binding activity. Involved in production of miRNAs involved in gene silencing by miRNA. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 13.3), lymph node (RPKM 12.9) and 25 other tissues See more Orthologs mouse all
ZC3H7B, Official Symbol ZC3H7Bprovided by HGNC Official Full Name zinc finger CCCH-type containing 7Bprovided by HGNC Primary source HGNC:HGNC:30869 See related Ensembl:ENSG00000100403 MIM:618206; AllianceGenome:HGNC:30869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RoXaN; ROXAN1 Summary This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts with the rotavirus non-structural protein NSP3. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 25.2), ovary (RPKM 25.2) and 25 other tissues See more Orthologs mouse all
ZC3H8, Official Symbol ZC3H8provided by HGNC Official Full Name zinc finger CCCH-type containing 8provided by HGNC Primary source HGNC:HGNC:30941 See related Ensembl:ENSG00000144161 AllianceGenome:HGNC:30941 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fliz1; ZC3HDC8 Summary Enables RNA binding activity. Involved in several processes, including positive regulation of thymocyte apoptotic process; regulation of transcription, DNA-templated; and snRNA transcription. Located in Cajal body; histone locus body; and transcriptionally active chromatin. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 3.7), thyroid (RPKM 3.3) and 25 other tissues See more Orthologs mouse all
ZC3HAV1, Official Symbol ZC3HAV1provided by HGNC Official Full Name zinc finger CCCH-type containing, antiviral 1provided by HGNC Primary source HGNC:HGNC:23721 See related Ensembl:ENSG00000105939 MIM:607312; AllianceGenome:HGNC:23721 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZAP; ZC3H2; ARTD13; PARP13; FLB6421; ZC3HDC2 Summary This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses, including Ebola virus, HIV and SARS-CoV-2 (which causes COVID-19). [provided by RefSeq, Sep 2021] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity. Expression Ubiquitous expression in bone marrow (RPKM 17.0), lymph node (RPKM 9.0) and 24 other tissues See more Orthologs mouse all
ZC3HAV1L, Official Symbol ZC3HAV1Lprovided by HGNC Official Full Name zinc finger CCCH-type containing, antiviral 1 likeprovided by HGNC Primary source HGNC:HGNC:22423 See related Ensembl:ENSG00000146858 AllianceGenome:HGNC:22423 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C7orf39 Summary Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 3.2), skin (RPKM 3.2) and 24 other tissues See more Orthologs mouse all
ZC3HC1, Official Symbol ZC3HC1provided by HGNC Official Full Name zinc finger C3HC-type containing 1provided by HGNC Primary source HGNC:HGNC:29913 See related Ensembl:ENSG00000091732 MIM:619746; AllianceGenome:HGNC:29913 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIPA; HSPC216 Summary This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in testis (RPKM 3.8), lymph node (RPKM 2.0) and 25 other tissues See more Orthologs mouse all
ZC4H2, Official Symbol ZC4H2provided by HGNC Official Full Name zinc finger C4H2-type containingprovided by HGNC Primary source HGNC:HGNC:24931 See related Ensembl:ENSG00000126970 MIM:300897; AllianceGenome:HGNC:24931 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCS; WWS; WRWF; MRXS4; HCA127; WRWFFR; KIAA1166 Summary This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in brain (RPKM 4.1), endometrium (RPKM 3.2) and 25 other tissues See more Orthologs mouse all