psui3905/ncbi_genes_summary huggingface dataset:
GPC5, Official Symbol GPC5provided by HGNC Official Full Name glypican 5provided by HGNC Primary source HGNC:HGNC:4453 See related Ensembl:ENSG00000179399 MIM:602446; AllianceGenome:HGNC:4453 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 1.8), testis (RPKM 1.4) and 7 other tissues See more Orthologs mouse all
GPC5-AS1, Official Symbol GPC5-AS1provided by HGNC Official Full Name GPC5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:39886 See related Ensembl:ENSG00000235984 AllianceGenome:HGNC:39886 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
GPC5-IT1, Official Symbol GPC5-IT1provided by HGNC Official Full Name GPC5 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41340 See related AllianceGenome:HGNC:41340 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GPC6, Official Symbol GPC6provided by HGNC Official Full Name glypican 6provided by HGNC Primary source HGNC:HGNC:4454 See related Ensembl:ENSG00000183098 MIM:604404; AllianceGenome:HGNC:4454 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OMIMD1 Summary The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1. [provided by RefSeq, Nov 2016] Expression Broad expression in gall bladder (RPKM 6.5), urinary bladder (RPKM 3.9) and 21 other tissues See more Orthologs mouse all
GPC6-AS1, Official Symbol GPC6-AS1provided by HGNC Official Full Name GPC6 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:39909 See related Ensembl:ENSG00000236520 AllianceGenome:HGNC:39909 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
GPCPD1, Official Symbol GPCPD1provided by HGNC Official Full Name glycerophosphocholine phosphodiesterase 1provided by HGNC Primary source HGNC:HGNC:26957 See related Ensembl:ENSG00000125772 MIM:614124; AllianceGenome:HGNC:26957 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EDI3; GDE5; GDPD6; PREI4 Summary Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Predicted to act upstream of or within skeletal muscle tissue development. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 31.5), spleen (RPKM 13.3) and 24 other tissues See more Orthologs mouse all
GPD1, Official Symbol GPD1provided by HGNC Official Full Name glycerol-3-phosphate dehydrogenase 1provided by HGNC Primary source HGNC:HGNC:4455 See related Ensembl:ENSG00000167588 MIM:138420; AllianceGenome:HGNC:4455 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPD-C; HTGTI; GPDH-C Summary This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] Expression Biased expression in fat (RPKM 448.5), kidney (RPKM 83.8) and 3 other tissues See more Orthologs mouse all
GPD1L, Official Symbol GPD1Lprovided by HGNC Official Full Name glycerol-3-phosphate dehydrogenase 1 likeprovided by HGNC Primary source HGNC:HGNC:28956 See related Ensembl:ENSG00000152642 MIM:611778; AllianceGenome:HGNC:28956 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPD1-L Summary The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010] Expression Broad expression in heart (RPKM 51.9), prostate (RPKM 37.6) and 23 other tissues See more Orthologs mouse all
GPD2, Official Symbol GPD2provided by HGNC Official Full Name glycerol-3-phosphate dehydrogenase 2provided by HGNC Primary source HGNC:HGNC:4456 See related Ensembl:ENSG00000115159 MIM:138430; AllianceGenome:HGNC:4456 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GDH2; GPDM; mGDH; mGPDH Summary The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010] Expression Ubiquitous expression in colon (RPKM 11.8), brain (RPKM 10.3) and 25 other tissues See more Orthologs mouse all
GPER1, Official Symbol GPER1provided by HGNC Official Full Name G protein-coupled estrogen receptor 1provided by HGNC Primary source HGNC:HGNC:4485 See related Ensembl:ENSG00000164850 MIM:601805; AllianceGenome:HGNC:4485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br Summary This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017] Expression Broad expression in fat (RPKM 4.9), kidney (RPKM 3.0) and 22 other tissues See more Orthologs mouse all
GPHA2, Official Symbol GPHA2provided by HGNC Official Full Name glycoprotein hormone subunit alpha 2provided by HGNC Primary source HGNC:HGNC:18054 See related Ensembl:ENSG00000149735 MIM:609651; AllianceGenome:HGNC:18054 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A2; GPA2; ZSIG51 Summary GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008] Expression Biased expression in pancreas (RPKM 14.6), testis (RPKM 3.2) and 2 other tissues See more Orthologs mouse all
GPHB5, Official Symbol GPHB5provided by HGNC Official Full Name glycoprotein hormone subunit beta 5provided by HGNC Primary source HGNC:HGNC:18055 See related Ensembl:ENSG00000179600 MIM:609652; AllianceGenome:HGNC:18055 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B5; GPB5; ZLUT1 Summary GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
GPHN, Official Symbol GPHNprovided by HGNC Official Full Name gephyrinprovided by HGNC Primary source HGNC:HGNC:15465 See related Ensembl:ENSG00000171723 MIM:603930; AllianceGenome:HGNC:15465 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPH; GEPH; HKPX1; GPHRYN; MOCODC Summary This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 7.5), liver (RPKM 6.6) and 25 other tissues See more Orthologs mouse all
GPI, Official Symbol GPIprovided by HGNC Official Full Name glucose-6-phosphate isomeraseprovided by HGNC Primary source HGNC:HGNC:4458 See related Ensembl:ENSG00000105220 MIM:172400; AllianceGenome:HGNC:4458 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMF; NLK; PGI; PHI; GNPI; SA36; SA-36 Summary This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] Expression Ubiquitous expression in heart (RPKM 54.9), fat (RPKM 52.6) and 25 other tissues See more Orthologs mouse all
GPIHBP1, Official Symbol GPIHBP1provided by HGNC Official Full Name glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1provided by HGNC Primary source HGNC:HGNC:24945 See related Ensembl:ENSG00000277494 MIM:612757; AllianceGenome:HGNC:24945 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYPL1D; GPI-HBP1 Summary This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] Expression Biased expression in fat (RPKM 74.5), lung (RPKM 16.0) and 2 other tissues See more Orthologs mouse all
GPKOW, Official Symbol GPKOWprovided by HGNC Official Full Name G-patch domain and KOW motifsprovided by HGNC Primary source HGNC:HGNC:30677 See related Ensembl:ENSG00000068394 MIM:301003; AllianceGenome:HGNC:30677 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as T54; Mos2; Spp2; GPATC5; GPATCH5 Summary This gene encodes a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. The encoded protein interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosome. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in brain (RPKM 10.0), fat (RPKM 7.5) and 25 other tissues See more Orthologs mouse all
GPLD1, Official Symbol GPLD1provided by HGNC Official Full Name glycosylphosphatidylinositol specific phospholipase D1provided by HGNC Primary source HGNC:HGNC:4459 See related Ensembl:ENSG00000112293 MIM:602515; AllianceGenome:HGNC:4459 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLD; GPIPLD; PIGPLD; GPIPLDM; PIGPLD1 Summary Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 12.6), skin (RPKM 4.0) and 8 other tissues See more Orthologs mouse all
GPM6A, Official Symbol GPM6Aprovided by HGNC Official Full Name glycoprotein M6Aprovided by HGNC Primary source HGNC:HGNC:4460 See related Ensembl:ENSG00000150625 MIM:601275; AllianceGenome:HGNC:4460 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M6A; GPM6 Summary Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 247.1) and lung (RPKM 8.5) See more Orthologs mouse all
GPM6B, Official Symbol GPM6Bprovided by HGNC Official Full Name glycoprotein M6Bprovided by HGNC Primary source HGNC:HGNC:4461 See related Ensembl:ENSG00000046653 MIM:300051; AllianceGenome:HGNC:4461 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M6B Summary This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016] Expression Biased expression in brain (RPKM 225.8) and prostate (RPKM 7.6) See more Orthologs mouse all
GPN1, Official Symbol GPN1provided by HGNC Official Full Name GPN-loop GTPase 1provided by HGNC Primary source HGNC:HGNC:17030 See related Ensembl:ENSG00000198522 MIM:611479; AllianceGenome:HGNC:17030 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XAB1; MBDIN; NTPBP; RPAP4; ATPBD1A Summary This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009] Expression Ubiquitous expression in testis (RPKM 15.4), thyroid (RPKM 13.8) and 25 other tissues See more Orthologs mouse all
GPN2, Official Symbol GPN2provided by HGNC Official Full Name GPN-loop GTPase 2provided by HGNC Primary source HGNC:HGNC:25513 See related Ensembl:ENSG00000142751 AllianceGenome:HGNC:25513 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATPBD1B Summary Predicted to enable GTPase activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 6.7), duodenum (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
GPN3, Official Symbol GPN3provided by HGNC Official Full Name GPN-loop GTPase 3provided by HGNC Primary source HGNC:HGNC:30186 See related Ensembl:ENSG00000111231 AllianceGenome:HGNC:30186 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATPBD1C Summary Predicted to enable GTPase activity. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 19.7), fat (RPKM 10.4) and 25 other tissues See more Orthologs mouse all
GPN3P1, Official Symbol GPN3P1provided by HGNC Official Full Name GPN-loop GTPase 3 pseudogene 1provided by HGNC Primary source HGNC:HGNC:44914 See related AllianceGenome:HGNC:44914 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GPNMB, Official Symbol GPNMBprovided by HGNC Official Full Name glycoprotein nmbprovided by HGNC Primary source HGNC:HGNC:4462 See related Ensembl:ENSG00000136235 MIM:604368; AllianceGenome:HGNC:4462 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NMB; HGFIN; PLCA3 Summary The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in skin (RPKM 225.4), gall bladder (RPKM 143.5) and 17 other tissues See more Orthologs mouse all
GPR101, Official Symbol GPR101provided by HGNC Official Full Name G protein-coupled receptor 101provided by HGNC Primary source HGNC:HGNC:14963 See related Ensembl:ENSG00000165370 MIM:300393; AllianceGenome:HGNC:14963 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR6; PAGH2; PITA2 Summary The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011] Orthologs mouse all
GPR107, Official Symbol GPR107provided by HGNC Official Full Name G protein-coupled receptor 107provided by HGNC Primary source HGNC:HGNC:17830 See related Ensembl:ENSG00000148358 MIM:618490; AllianceGenome:HGNC:17830 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCDRP; LUSTR1; bA138E2.2 Summary Predicted to enable clathrin heavy chain binding activity. Predicted to be involved in clathrin-dependent endocytosis. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 20.9), brain (RPKM 13.5) and 25 other tissues See more Orthologs mouse all
GPR108, Official Symbol GPR108provided by HGNC Official Full Name G protein-coupled receptor 108provided by HGNC Primary source HGNC:HGNC:17829 See related Ensembl:ENSG00000125734 MIM:618491; AllianceGenome:HGNC:17829 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LUSTR2 Summary Predicted to be involved in negative regulation of toll-like receptor signaling pathway. Located in trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 21.4), duodenum (RPKM 17.0) and 25 other tissues See more Orthologs mouse all
GPR119, Official Symbol GPR119provided by HGNC Official Full Name G protein-coupled receptor 119provided by HGNC Primary source HGNC:HGNC:19060 See related Ensembl:ENSG00000147262 MIM:300513; AllianceGenome:HGNC:19060 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR2 Summary This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010] Orthologs mouse all
GPR12, Official Symbol GPR12provided by HGNC Official Full Name G protein-coupled receptor 12provided by HGNC Primary source HGNC:HGNC:4466 See related Ensembl:ENSG00000132975 MIM:600752; AllianceGenome:HGNC:4466 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR12; GPCR21; PPP1R84 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cellular calcium ion homeostasis. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 3.0) and salivary gland (RPKM 0.6) See more Orthologs mouse all
GPR132, Official Symbol GPR132provided by HGNC Official Full Name G protein-coupled receptor 132provided by HGNC Primary source HGNC:HGNC:17482 See related Ensembl:ENSG00000183484 MIM:606167; AllianceGenome:HGNC:17482 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2A Summary This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in appendix (RPKM 4.0), lymph node (RPKM 3.6) and 20 other tissues See more Orthologs mouse all
GPR135, Official Symbol GPR135provided by HGNC Official Full Name G protein-coupled receptor 135provided by HGNC Primary source HGNC:HGNC:19991 See related Ensembl:ENSG00000181619 MIM:607970; AllianceGenome:HGNC:19991 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HUMNPIIY20 Summary Enables arrestin family protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in endosome and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 3.7), ovary (RPKM 1.1) and 20 other tissues See more Orthologs mouse all
GPR137, Official Symbol GPR137provided by HGNC Official Full Name G protein-coupled receptor 137provided by HGNC Primary source HGNC:HGNC:24300 See related Ensembl:ENSG00000173264 AllianceGenome:HGNC:24300 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C11orf4; GPR137A; TM7SF1L1 Summary Predicted to be involved in several processes, including negative regulation of bone resorption; negative regulation of osteoclast differentiation; and positive regulation of TORC1 signaling. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 30.3), brain (RPKM 9.0) and 24 other tissues See more Orthologs mouse all
GPR137B, Official Symbol GPR137Bprovided by HGNC Official Full Name G protein-coupled receptor 137Bprovided by HGNC Primary source HGNC:HGNC:11862 See related Ensembl:ENSG00000077585 MIM:604658; AllianceGenome:HGNC:11862 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM7SF1 Summary Involved in several processes, including positive regulation of TORC1 signaling; positive regulation of protein localization to lysosome; and regulation of GTPase activity. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 12.9), brain (RPKM 8.4) and 23 other tissues See more Orthologs mouse all
GPR137C, Official Symbol GPR137Cprovided by HGNC Official Full Name G protein-coupled receptor 137Cprovided by HGNC Primary source HGNC:HGNC:25445 See related Ensembl:ENSG00000180998 AllianceGenome:HGNC:25445 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM7SF1L2 Summary Predicted to be involved in positive regulation of TORC1 signaling. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 7.8), testis (RPKM 1.4) and 8 other tissues See more Orthologs mouse all
GPR139, Official Symbol GPR139provided by HGNC Official Full Name G protein-coupled receptor 139provided by HGNC Primary source HGNC:HGNC:19995 See related Ensembl:ENSG00000180269 MIM:618448; AllianceGenome:HGNC:19995 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR3; GPRg1 Summary This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all
GPR141, Official Symbol GPR141provided by HGNC Official Full Name G protein-coupled receptor 141provided by HGNC Primary source HGNC:HGNC:19997 See related Ensembl:ENSG00000187037 MIM:609045; AllianceGenome:HGNC:19997 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR13 Summary GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008] Expression Biased expression in bone marrow (RPKM 2.2), appendix (RPKM 0.5) and 10 other tissues See more Orthologs all
GPR141BP, Official Symbol GPR141BPprovided by HGNC Official Full Name G protein-coupled receptor 141B, pseudogeneprovided by HGNC Primary source HGNC:HGNC:53813 See related Ensembl:ENSG00000283444 AllianceGenome:HGNC:53813 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GPR142, Official Symbol GPR142provided by HGNC Official Full Name G protein-coupled receptor 142provided by HGNC Primary source HGNC:HGNC:20088 See related Ensembl:ENSG00000257008 MIM:609046; AllianceGenome:HGNC:20088 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR2; GPRg1b Summary GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008] Expression Biased expression in stomach (RPKM 1.1), spleen (RPKM 0.3) and 9 other tissues See more Orthologs mouse all
GPR143, Official Symbol GPR143provided by HGNC Official Full Name G protein-coupled receptor 143provided by HGNC Primary source HGNC:HGNC:20145 See related Ensembl:ENSG00000101850 MIM:300808; AllianceGenome:HGNC:20145 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OA1; NYS6 Summary This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009] Expression Broad expression in skin (RPKM 3.2), placenta (RPKM 2.0) and 16 other tissues See more Orthologs mouse all
GPR146, Official Symbol GPR146provided by HGNC Official Full Name G protein-coupled receptor 146provided by HGNC Primary source HGNC:HGNC:21718 See related Ensembl:ENSG00000164849 AllianceGenome:HGNC:21718 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR8 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 14.9), lung (RPKM 4.6) and 18 other tissues See more Orthologs mouse all
GPR148, Official Symbol GPR148provided by HGNC Official Full Name G protein-coupled receptor 148provided by HGNC Primary source HGNC:HGNC:23623 See related Ensembl:ENSG00000173302 AllianceGenome:HGNC:23623 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTR; PGR6 Summary Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
GPR149, Official Symbol GPR149provided by HGNC Official Full Name G protein-coupled receptor 149provided by HGNC Primary source HGNC:HGNC:23627 See related Ensembl:ENSG00000174948 AllianceGenome:HGNC:23627 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as R35; IEDA; PGR10 Summary This gene encodes a seven-transmembrane G protein coupled receptor (GPCR) class A family member. Although categorized as a class A GPCR, the encoded protein lacks the first two charged amino acids of the highly conserved Asp-Arg-Tyr (DRY) motif found in the third transmembrane helix of class A receptors which is important for efficient G protein-coupled signal transduction. Mice with a knockout of the orthologous gene are viable and have normal maturation of the ovarian follicle, but show enhanced fertility and ovulation. All GPCRs have a common structural architecture consisting of seven transmembrane alpha-helices interconnected by three extracellular and three intracellular loops. A general feature of GPCR signaling is agonist-induced conformational changes in the receptor, leading to activation of the heterotrimeric G proteins, which consist of the guanine nucleotide-binding G-alpha subunit and the dimeric G-beta-gamma subunits. The activated G proteins then bind to and activate numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017] Expression Low expression observed in reference dataset See more Orthologs mouse all
GPR15, Official Symbol GPR15provided by HGNC Official Full Name G protein-coupled receptor 15provided by HGNC Primary source HGNC:HGNC:4469 See related Ensembl:ENSG00000154165 MIM:601166; AllianceGenome:HGNC:4469 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BOB Summary This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012] Orthologs mouse all
GPR150, Official Symbol GPR150provided by HGNC Official Full Name G protein-coupled receptor 150provided by HGNC Primary source HGNC:HGNC:23628 See related Ensembl:ENSG00000178015 AllianceGenome:HGNC:23628 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR11 Summary This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017] Orthologs mouse all
GPR151, Official Symbol GPR151provided by HGNC Official Full Name G protein-coupled receptor 151provided by HGNC Primary source HGNC:HGNC:23624 See related Ensembl:ENSG00000173250 MIM:618487; AllianceGenome:HGNC:23624 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR; PGR7; GALR4; GALRL; GPCR-2037 Summary This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017] Orthologs mouse all
GPR152, Official Symbol GPR152provided by HGNC Official Full Name G protein-coupled receptor 152provided by HGNC Primary source HGNC:HGNC:23622 See related Ensembl:ENSG00000175514 AllianceGenome:HGNC:23622 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR5 Summary Enables identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
GPR153, Official Symbol GPR153provided by HGNC Official Full Name G protein-coupled receptor 153provided by HGNC Primary source HGNC:HGNC:23618 See related Ensembl:ENSG00000158292 MIM:614269; AllianceGenome:HGNC:23618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR1 Summary This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017] Expression Broad expression in colon (RPKM 6.6), fat (RPKM 4.7) and 21 other tissues See more Orthologs mouse all
GPR155, Official Symbol GPR155provided by HGNC Official Full Name G protein-coupled receptor 155provided by HGNC Primary source HGNC:HGNC:22951 See related Ensembl:ENSG00000163328 AllianceGenome:HGNC:22951 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEP.7; PGR22; DEPDC3 Summary Involved in cognition. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in stomach (RPKM 11.2), brain (RPKM 8.6) and 24 other tissues See more Orthologs mouse all
GPR156, Official Symbol GPR156provided by HGNC Official Full Name G protein-coupled receptor 156provided by HGNC Primary source HGNC:HGNC:20844 See related Ensembl:ENSG00000175697 MIM:610464; AllianceGenome:HGNC:20844 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR28; GABABL Summary G protein-coupled receptors (GPCRs) are a large superfamily of cell surface receptors characterized by 7 helical transmembrane domains, together with N-terminal extracellular and C-terminal intracellular domains.[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 1.8), ovary (RPKM 0.3) and 7 other tissues See more Orthologs mouse all
GPR157, Official Symbol GPR157provided by HGNC Official Full Name G protein-coupled receptor 157provided by HGNC Primary source HGNC:HGNC:23687 See related Ensembl:ENSG00000180758 AllianceGenome:HGNC:23687 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway and radial glial cell differentiation. Predicted to be located in ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 10.7), skin (RPKM 5.0) and 22 other tissues See more Orthologs mouse all
GPR158, Official Symbol GPR158provided by HGNC Official Full Name G protein-coupled receptor 158provided by HGNC Primary source HGNC:HGNC:23689 See related Ensembl:ENSG00000151025 MIM:614573; AllianceGenome:HGNC:23689 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and protein localization to plasma membrane. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 11.3), adrenal (RPKM 0.9) and 1 other tissue See more Orthologs mouse all
GPR158-AS1, Official Symbol GPR158-AS1provided by HGNC Official Full Name GPR158 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44163 See related Ensembl:ENSG00000233642 AllianceGenome:HGNC:44163 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in brain (RPKM 1.2) and testis (RPKM 0.1) See more
GPR160, Official Symbol GPR160provided by HGNC Official Full Name G protein-coupled receptor 160provided by HGNC Primary source HGNC:HGNC:23693 See related Ensembl:ENSG00000173890 AllianceGenome:HGNC:23693 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPCR1; GPCR150 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in small intestine (RPKM 20.7), duodenum (RPKM 16.2) and 15 other tissues See more Orthologs mouse all