psui3905/ncbi_genes_summary huggingface dataset:
ZNF347, Official Symbol ZNF347provided by HGNC Official Full Name zinc finger protein 347provided by HGNC Primary source HGNC:HGNC:16447 See related Ensembl:ENSG00000197937 AllianceGenome:HGNC:16447 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF1111 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 2.5), thyroid (RPKM 2.3) and 25 other tissues See more Orthologs all
ZNF35, Official Symbol ZNF35provided by HGNC Official Full Name zinc finger protein 35provided by HGNC Primary source HGNC:HGNC:13099 See related Ensembl:ENSG00000169981 MIM:194533; AllianceGenome:HGNC:13099 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HF10; HF.10; Zfp105 Summary Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in cellular response to retinoic acid; regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 5.6), urinary bladder (RPKM 2.4) and 25 other tissues See more Orthologs mouse all
ZNF350, Official Symbol ZNF350provided by HGNC Official Full Name zinc finger protein 350provided by HGNC Primary source HGNC:HGNC:16656 See related Ensembl:ENSG00000256683 MIM:605422; AllianceGenome:HGNC:16656 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFQR; ZBRK1 Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 10.8), thyroid (RPKM 4.3) and 24 other tissues See more Orthologs all
ZNF350-AS1, Official Symbol ZNF350-AS1provided by HGNC Official Full Name ZNF350 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48598 See related Ensembl:ENSG00000269235 AllianceGenome:HGNC:48598 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCCAT3; uc002pyc Expression Biased expression in prostate (RPKM 4.6), testis (RPKM 4.4) and 10 other tissues See more
ZNF354A, Official Symbol ZNF354Aprovided by HGNC Official Full Name zinc finger protein 354Aprovided by HGNC Primary source HGNC:HGNC:11628 See related Ensembl:ENSG00000169131 MIM:602444; AllianceGenome:HGNC:11628 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EZNF; HKL1; KID1; KID-1; TCF17; HEL104 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol; nucleolus; and nucleoplasm. Biomarker of in situ carcinoma and seminoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.1), thyroid (RPKM 4.4) and 25 other tissues See more Orthologs mouse all
ZNF354B, Official Symbol ZNF354Bprovided by HGNC Official Full Name zinc finger protein 354Bprovided by HGNC Primary source HGNC:HGNC:17197 See related Ensembl:ENSG00000178338 AllianceGenome:HGNC:17197 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KID2 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 4.5), endometrium (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
ZNF354C, Official Symbol ZNF354Cprovided by HGNC Official Full Name zinc finger protein 354Cprovided by HGNC Primary source HGNC:HGNC:16736 See related Ensembl:ENSG00000177932 MIM:619511; AllianceGenome:HGNC:16736 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KID3 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 3.8), thyroid (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
ZNF358, Official Symbol ZNF358provided by HGNC Official Full Name zinc finger protein 358provided by HGNC Primary source HGNC:HGNC:16838 See related Ensembl:ENSG00000198816 MIM:619496; AllianceGenome:HGNC:16838 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFEND Summary Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic forelimb morphogenesis; neural tube development; and stem cell population maintenance. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 21.7), ovary (RPKM 18.2) and 24 other tissues See more Orthologs mouse all
ZNF362, Official Symbol ZNF362provided by HGNC Official Full Name zinc finger protein 362provided by HGNC Primary source HGNC:HGNC:18079 See related Ensembl:ENSG00000160094 AllianceGenome:HGNC:18079 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RN; lin-29 Summary Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 4.1), kidney (RPKM 3.8) and 25 other tissues See more Orthologs mouse all
ZNF365, Official Symbol ZNF365provided by HGNC Official Full Name zinc finger protein 365provided by HGNC Primary source HGNC:HGNC:18194 See related Ensembl:ENSG00000138311 MIM:607818; AllianceGenome:HGNC:18194 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UAN; Su48; ZNF365D Summary This gene encodes a zinc finger protein that may play a role in the repair of DNA damage and maintenance of genome stability. The N-terminal C2H2 zinc finger motif is required to form a protein complex with PARP1 and MRE11, which are known to be involved in the restart of stalled DNA replication forks. A mutation in this gene may be associated with breast cancer susceptibility. [provided by RefSeq, Mar 2020] Expression Biased expression in brain (RPKM 9.2), esophagus (RPKM 2.1) and 3 other tissues See more Orthologs mouse all
ZNF366, Official Symbol ZNF366provided by HGNC Official Full Name zinc finger protein 366provided by HGNC Primary source HGNC:HGNC:18316 See related Ensembl:ENSG00000178175 MIM:610159; AllianceGenome:HGNC:18316 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DCSCRIPT; DC-SCRIPT Summary Enables estrogen receptor binding activity and transcription corepressor activity. Involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in placenta (RPKM 4.6), fat (RPKM 4.5) and 21 other tissues See more Orthologs mouse all
ZNF367, Official Symbol ZNF367provided by HGNC Official Full Name zinc finger protein 367provided by HGNC Primary source HGNC:HGNC:18320 See related Ensembl:ENSG00000165244 MIM:610160; AllianceGenome:HGNC:18320 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFF29; ZFF29; CDC14B Summary Enables DNA-binding transcription factor activity. Acts upstream of or within regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 8.1), testis (RPKM 3.6) and 21 other tissues See more Orthologs mouse all
ZNF37A, Official Symbol ZNF37Aprovided by HGNC Official Full Name zinc finger protein 37Aprovided by HGNC Primary source HGNC:HGNC:13102 See related Ensembl:ENSG00000075407 MIM:616085; AllianceGenome:HGNC:13102 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX21; ZNF37 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.1), endometrium (RPKM 2.4) and 25 other tissues See more Orthologs all
ZNF37BP, Official Symbol ZNF37BPprovided by HGNC Official Full Name zinc finger protein 37B, pseudogeneprovided by HGNC Primary source HGNC:HGNC:13103 See related Ensembl:ENSG00000234420 AllianceGenome:HGNC:13103 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX21; ZNF37B Expression Ubiquitous expression in spleen (RPKM 4.0), endometrium (RPKM 3.6) and 25 other tissues See more
ZNF37CP, Official Symbol ZNF37CPprovided by HGNC Official Full Name zinc finger protein 37C, pseudogeneprovided by HGNC Primary source HGNC:HGNC:29445 See related Ensembl:ENSG00000151963 AllianceGenome:HGNC:29445 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF37C; BA775A3.1
ZNF382, Official Symbol ZNF382provided by HGNC Official Full Name zinc finger protein 382provided by HGNC Primary source HGNC:HGNC:17409 See related Ensembl:ENSG00000161298 MIM:609516; AllianceGenome:HGNC:17409 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KS1 Summary This gene encodes a KRAB domain zinc finger transcription factor (KZNF). KZNFs play critical roles in the regulation of many cellular processes including differentiation, proliferation and apoptosis. The encoded protein inhibits activating protein 1 (AP-1) and nuclear factor kappa-B (NF-kB) signaling and may function as a tumor suppressor in multiple carcinomas. This gene is found in a cluster with other zinc finger protein genes on the long arm of chromosome 19, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] Expression Broad expression in brain (RPKM 2.5), testis (RPKM 1.9) and 22 other tissues See more Orthologs mouse all
ZNF383, Official Symbol ZNF383provided by HGNC Official Full Name zinc finger protein 383provided by HGNC Primary source HGNC:HGNC:18609 See related Ensembl:ENSG00000188283 MIM:619499; AllianceGenome:HGNC:18609 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSD17; Zfp383 Summary The protein encoded by this gene is a KRAB-related zinc finger protein that inhibits the transcription of some MAPK signaling pathway genes. The repressor activity resides in the KRAB domain of the encoded protein. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in thyroid (RPKM 1.1), ovary (RPKM 1.1) and 25 other tissues See more Orthologs all
ZNF384, Official Symbol ZNF384provided by HGNC Official Full Name zinc finger protein 384provided by HGNC Primary source HGNC:HGNC:11955 See related Ensembl:ENSG00000126746 MIM:609951; AllianceGenome:HGNC:11955 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NP; CIZ; NMP4; CAGH1; ERDA2; TNRC1; CAGH1A Summary This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011] Expression Ubiquitous expression in bone marrow (RPKM 12.2), testis (RPKM 12.0) and 25 other tissues See more Orthologs mouse all
ZNF385A, Official Symbol ZNF385Aprovided by HGNC Official Full Name zinc finger protein 385Aprovided by HGNC Primary source HGNC:HGNC:17521 See related Ensembl:ENSG00000161642 MIM:609124; AllianceGenome:HGNC:17521 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HZF; RZF; ZFP385; ZNF385 Summary Zinc finger proteins, such as ZNF385A, are regulatory proteins that act as transcription factors, bind single- or double-stranded RNA, or interact with other proteins (Sharma et al., 2004 [PubMed 15527981]).[supplied by OMIM, Oct 2008] Expression Broad expression in skin (RPKM 29.1), fat (RPKM 16.9) and 19 other tissues See more Orthologs mouse all
ZNF385B, Official Symbol ZNF385Bprovided by HGNC Official Full Name zinc finger protein 385Bprovided by HGNC Primary source HGNC:HGNC:26332 See related Ensembl:ENSG00000144331 MIM:612344; AllianceGenome:HGNC:26332 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF533 Summary Enables p53 binding activity. Involved in intrinsic apoptotic signaling pathway by p53 class mediator. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lung (RPKM 1.7), heart (RPKM 1.4) and 14 other tissues See more Orthologs mouse all
ZNF385C, Official Symbol ZNF385Cprovided by HGNC Official Full Name zinc finger protein 385Cprovided by HGNC Primary source HGNC:HGNC:33722 See related Ensembl:ENSG00000187595 AllianceGenome:HGNC:33722 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 4.2), testis (RPKM 3.8) and 25 other tissues See more Orthologs mouse all
ZNF385D, Official Symbol ZNF385Dprovided by HGNC Official Full Name zinc finger protein 385Dprovided by HGNC Primary source HGNC:HGNC:26191 See related Ensembl:ENSG00000151789 AllianceGenome:HGNC:26191 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF659 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 1.9), brain (RPKM 1.5) and 16 other tissues See more Orthologs all
ZNF385D-AS1, Official Symbol ZNF385D-AS1provided by HGNC Official Full Name ZNF385D antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41136 See related Ensembl:ENSG00000225542 AllianceGenome:HGNC:41136 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZNF385D-AS2, Official Symbol ZNF385D-AS2provided by HGNC Official Full Name ZNF385D antisense RNA 2provided by HGNC Primary source HGNC:HGNC:42420 See related Ensembl:ENSG00000223351 AllianceGenome:HGNC:42420 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZNF391, Official Symbol ZNF391provided by HGNC Official Full Name zinc finger protein 391provided by HGNC Primary source HGNC:HGNC:18779 See related Ensembl:ENSG00000124613 AllianceGenome:HGNC:18779 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ153G14.3 Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 2.3), thyroid (RPKM 2.1) and 23 other tissues See more Orthologs all
ZNF394, Official Symbol ZNF394provided by HGNC Official Full Name zinc finger protein 394provided by HGNC Primary source HGNC:HGNC:18832 See related Ensembl:ENSG00000160908 MIM:619300; AllianceGenome:HGNC:18832 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZSCAN46; ZKSCAN14 Summary The protein encoded by this gene is a zinc finger protein that inhibits the transcription of mitogen-activated protein kinase signaling pathways. The encoded protein may be involved in cardiac function. [provided by RefSeq, Sep 2016] Expression Broad expression in bone marrow (RPKM 26.0), spleen (RPKM 6.3) and 24 other tissues See more Orthologs mouse all
ZNF395, Official Symbol ZNF395provided by HGNC Official Full Name zinc finger protein 395provided by HGNC Primary source HGNC:HGNC:18737 See related Ensembl:ENSG00000186918 MIM:609494; AllianceGenome:HGNC:18737 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14 Summary Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 29.1), placenta (RPKM 20.8) and 25 other tissues See more Orthologs mouse all
ZNF396, Official Symbol ZNF396provided by HGNC Official Full Name zinc finger protein 396provided by HGNC Primary source HGNC:HGNC:18824 See related Ensembl:ENSG00000186496 MIM:609600; AllianceGenome:HGNC:18824 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZSCAN14 Summary Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 1.8), testis (RPKM 1.3) and 24 other tissues See more Orthologs all
ZNF397, Official Symbol ZNF397provided by HGNC Official Full Name zinc finger protein 397provided by HGNC Primary source HGNC:HGNC:18818 See related Ensembl:ENSG00000186812 MIM:609601; AllianceGenome:HGNC:18818 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF47; ZSCAN15 Summary This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in thyroid (RPKM 5.5), brain (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
ZNF398, Official Symbol ZNF398provided by HGNC Official Full Name zinc finger protein 398provided by HGNC Primary source HGNC:HGNC:18373 See related Ensembl:ENSG00000197024 MIM:618593; AllianceGenome:HGNC:18373 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P51; P71; ZER6 Summary This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 4.5), esophagus (RPKM 2.9) and 25 other tissues See more Orthologs all
ZNF402P, Official Symbol ZNF402Pprovided by HGNC Official Full Name zinc finger protein 402, pseudogeneprovided by HGNC Primary source HGNC:HGNC:19292 See related Ensembl:ENSG00000220248 AllianceGenome:HGNC:19292 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZNF404, Official Symbol ZNF404provided by HGNC Official Full Name zinc finger protein 404provided by HGNC Primary source HGNC:HGNC:19417 See related Ensembl:ENSG00000176222 AllianceGenome:HGNC:19417 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 3.0), testis (RPKM 2.6) and 25 other tissues See more Orthologs all
ZNF407, Official Symbol ZNF407provided by HGNC Official Full Name zinc finger protein 407provided by HGNC Primary source HGNC:HGNC:19904 See related Ensembl:ENSG00000215421 MIM:615894; AllianceGenome:HGNC:19904 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIMHA Summary This gene encodes a zinc finger protein whose exact function is not known. It may be involved in transcriptional regulation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Ubiquitous expression in testis (RPKM 1.7), ovary (RPKM 1.3) and 25 other tissues See more Orthologs mouse all
ZNF407-AS1, Official Symbol ZNF407-AS1provided by HGNC Official Full Name ZNF407 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44331 See related Ensembl:ENSG00000264247 AllianceGenome:HGNC:44331 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LINC00909 Expression Ubiquitous expression in ovary (RPKM 3.1), brain (RPKM 3.1) and 25 other tissues See more
ZNF408, Official Symbol ZNF408provided by HGNC Official Full Name zinc finger protein 408provided by HGNC Primary source HGNC:HGNC:20041 See related Ensembl:ENSG00000175213 MIM:616454; AllianceGenome:HGNC:20041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EVR6; RP72 Summary The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016] Expression Ubiquitous expression in bone marrow (RPKM 5.1), ovary (RPKM 3.1) and 25 other tissues See more Orthologs mouse all
ZNF41, Official Symbol ZNF41provided by HGNC Official Full Name zinc finger protein 41provided by HGNC Primary source HGNC:HGNC:13107 See related Ensembl:ENSG00000147124 MIM:314995; AllianceGenome:HGNC:13107 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRX89 Summary This gene encodes a protein that contains KRAB-A and KRAB-B domains multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. An initial study suggested that this gene may be associated with X-linked cognitive disability, but a later study has called this finding into question (PMID:23871722).[provided by RefSeq, Apr 2016] Expression Ubiquitous expression in thyroid (RPKM 3.3), heart (RPKM 2.6) and 25 other tissues See more Orthologs all
ZNF410, Official Symbol ZNF410provided by HGNC Official Full Name zinc finger protein 410provided by HGNC Primary source HGNC:HGNC:20144 See related Ensembl:ENSG00000119725 MIM:619427; AllianceGenome:HGNC:20144 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APA1; APA-1 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 23.4), bone marrow (RPKM 18.5) and 25 other tissues See more Orthologs mouse all
ZNF414, Official Symbol ZNF414provided by HGNC Official Full Name zinc finger protein 414provided by HGNC Primary source HGNC:HGNC:20630 See related Ensembl:ENSG00000133250 AllianceGenome:HGNC:20630 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP414 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 4.4), prostate (RPKM 4.1) and 25 other tissues See more Orthologs mouse all
ZNF415, Official Symbol ZNF415provided by HGNC Official Full Name zinc finger protein 415provided by HGNC Primary source HGNC:HGNC:20636 See related Ensembl:ENSG00000170954 MIM:619506; AllianceGenome:HGNC:20636 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Pact; ZfLp Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in fibrillar center and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 8.7), adrenal (RPKM 5.5) and 22 other tissues See more Orthologs all
ZNF415P1, Official Symbol ZNF415P1provided by HGNC Official Full Name zinc finger protein 415 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49869 See related Ensembl:ENSG00000266127 AllianceGenome:HGNC:49869 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZNF416, Official Symbol ZNF416provided by HGNC Official Full Name zinc finger protein 416provided by HGNC Primary source HGNC:HGNC:20645 See related Ensembl:ENSG00000083817 AllianceGenome:HGNC:20645 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cardiac muscle hypertrophy; negative regulation of cell growth involved in cardiac muscle cell development; and negative regulation of protein phosphorylation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.5), thyroid (RPKM 1.9) and 25 other tissues See more Orthologs all
ZNF417, Official Symbol ZNF417provided by HGNC Official Full Name zinc finger protein 417provided by HGNC Primary source HGNC:HGNC:20646 See related Ensembl:ENSG00000173480 AllianceGenome:HGNC:20646 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.9), prostate (RPKM 3.7) and 25 other tissues See more Orthologs all
ZNF418, Official Symbol ZNF418provided by HGNC Official Full Name zinc finger protein 418provided by HGNC Primary source HGNC:HGNC:20647 See related Ensembl:ENSG00000196724 MIM:619509; AllianceGenome:HGNC:20647 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP418 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 1.8), skin (RPKM 1.6) and 25 other tissues See more Orthologs all
ZNF419, Official Symbol ZNF419provided by HGNC Official Full Name zinc finger protein 419provided by HGNC Primary source HGNC:HGNC:20648 See related Ensembl:ENSG00000105136 MIM:617410; AllianceGenome:HGNC:20648 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZAPHIR; ZNF419A Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 5.2), spleen (RPKM 4.2) and 25 other tissues See more Orthologs all
ZNF420, Official Symbol ZNF420provided by HGNC Official Full Name zinc finger protein 420provided by HGNC Primary source HGNC:HGNC:20649 See related Ensembl:ENSG00000197050 MIM:617216; AllianceGenome:HGNC:20649 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APAK Summary The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in testis (RPKM 3.6), ovary (RPKM 3.4) and 25 other tissues See more Orthologs all
ZNF423, Official Symbol ZNF423provided by HGNC Official Full Name zinc finger protein 423provided by HGNC Primary source HGNC:HGNC:16762 See related Ensembl:ENSG00000102935 MIM:604557; AllianceGenome:HGNC:16762 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OAZ; Roaz; hOAZ; Ebfaz; JBTS19; NPHP14; ZFP423; Zfp104 Summary The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012] Expression Ubiquitous expression in fat (RPKM 2.2), ovary (RPKM 1.9) and 23 other tissues See more Orthologs mouse all
ZNF425, Official Symbol ZNF425provided by HGNC Official Full Name zinc finger protein 425provided by HGNC Primary source HGNC:HGNC:20690 See related Ensembl:ENSG00000204947 MIM:619507; AllianceGenome:HGNC:20690 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 1.8), brain (RPKM 1.7) and 25 other tissues See more Orthologs all
ZNF426, Official Symbol ZNF426provided by HGNC Official Full Name zinc finger protein 426provided by HGNC Primary source HGNC:HGNC:20725 See related Ensembl:ENSG00000130818 AllianceGenome:HGNC:20725 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K-RBP Summary Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in esophagus (RPKM 5.6), ovary (RPKM 2.9) and 25 other tissues See more Orthologs all
ZNF426-DT, Official Symbol ZNF426-DTprovided by HGNC Official Full Name ZNF426 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:53777 See related Ensembl:ENSG00000278611 AllianceGenome:HGNC:53777 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZNF428, Official Symbol ZNF428provided by HGNC Official Full Name zinc finger protein 428provided by HGNC Primary source HGNC:HGNC:20804 See related Ensembl:ENSG00000131116 AllianceGenome:HGNC:20804 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Zfp428; C19orf37 Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 19.1), testis (RPKM 14.8) and 25 other tissues See more Orthologs mouse all
ZNF429, Official Symbol ZNF429provided by HGNC Official Full Name zinc finger protein 429provided by HGNC Primary source HGNC:HGNC:20817 See related Ensembl:ENSG00000197013 AllianceGenome:HGNC:20817 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 2.7), ovary (RPKM 1.8) and 25 other tissues See more Orthologs all
ZNF43, Official Symbol ZNF43provided by HGNC Official Full Name zinc finger protein 43provided by HGNC Primary source HGNC:HGNC:13109 See related Ensembl:ENSG00000198521 MIM:603972; AllianceGenome:HGNC:13109 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HTF6; KOX27; ZNF39L1 Summary This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 1.7), ovary (RPKM 1.6) and 24 other tissues See more Orthologs all
ZNF430, Official Symbol ZNF430provided by HGNC Official Full Name zinc finger protein 430provided by HGNC Primary source HGNC:HGNC:20808 See related Ensembl:ENSG00000118620 AllianceGenome:HGNC:20808 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in substantia nigra development. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 6.0), thyroid (RPKM 5.3) and 24 other tissues See more Orthologs all
ZNF431, Official Symbol ZNF431provided by HGNC Official Full Name zinc finger protein 431provided by HGNC Primary source HGNC:HGNC:20809 See related Ensembl:ENSG00000196705 MIM:619505; AllianceGenome:HGNC:20809 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP932 Summary This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein may negatively regulate transcription of target genes, including the hedgehog signaling pathway receptor patched 1, by interacting with histone deacetylases. Mutations in this gene may be associated with non-syndromic facial clefting in human patients. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in ovary (RPKM 3.5), thyroid (RPKM 3.0) and 24 other tissues See more
ZNF432, Official Symbol ZNF432provided by HGNC Official Full Name zinc finger protein 432provided by HGNC Primary source HGNC:HGNC:20810 See related Ensembl:ENSG00000256087 AllianceGenome:HGNC:20810 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 5.4), testis (RPKM 3.4) and 25 other tissues See more Orthologs all
ZNF433, Official Symbol ZNF433provided by HGNC Official Full Name zinc finger protein 433provided by HGNC Primary source HGNC:HGNC:20811 See related Ensembl:ENSG00000197647 AllianceGenome:HGNC:20811 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 9.0), thyroid (RPKM 2.5) and 21 other tissues See more Orthologs all