psui3905/ncbi_genes_summary huggingface dataset:
RUVBL1, Official Symbol RUVBL1provided by HGNC Official Full Name RuvB like AAA ATPase 1provided by HGNC Primary source HGNC:HGNC:10474 See related Ensembl:ENSG00000175792 MIM:603449; AllianceGenome:HGNC:10474 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RVB1; TIH1; ECP54; TIP49; ECP-54; INO80H; NMP238; PONTIN; TIP49A; NMP 238; Pontin52 Summary This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in testis (RPKM 12.6), placenta (RPKM 10.9) and 25 other tissues See more Orthologs mouse all
RUVBL1-AS1, Official Symbol RUVBL1-AS1provided by HGNC Official Full Name RUVBL1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40514 See related Ensembl:ENSG00000239608 AllianceGenome:HGNC:40514 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
RUVBL2, Official Symbol RUVBL2provided by HGNC Official Full Name RuvB like AAA ATPase 2provided by HGNC Primary source HGNC:HGNC:10475 See related Ensembl:ENSG00000183207 MIM:604788; AllianceGenome:HGNC:10475 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RVB2; TIH2; ECP51; TIP48; CGI-46; ECP-51; INO80J; REPTIN; TIP49B; TAP54-beta Summary This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 64.1), colon (RPKM 12.0) and 24 other tissues See more Orthologs mouse all
RUVBL2P1, Official Symbol RUVBL2P1provided by HGNC Official Full Name RUVBL2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:55128 See related Ensembl:ENSG00000226802 AllianceGenome:HGNC:55128 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RWDD1, Official Symbol RWDD1provided by HGNC Official Full Name RWD domain containing 1provided by HGNC Primary source HGNC:HGNC:20993 See related Ensembl:ENSG00000111832 AllianceGenome:HGNC:20993 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGI-24; PTD013 Summary Predicted to be involved in several processes, including cellular response to lipid; cytoplasmic translation; and positive regulation of androgen receptor activity. Predicted to be located in cytoplasm. Predicted to be part of polysome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 22.0), adrenal (RPKM 19.3) and 25 other tissues See more Orthologs mouse all
RWDD2A, Official Symbol RWDD2Aprovided by HGNC Official Full Name RWD domain containing 2Aprovided by HGNC Primary source HGNC:HGNC:21385 See related Ensembl:ENSG00000013392 AllianceGenome:HGNC:21385 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RWDD2; dJ747H23.2 Expression Broad expression in prostate (RPKM 6.9), testis (RPKM 5.4) and 24 other tissues See more Orthologs mouse all
RWDD2B, Official Symbol RWDD2Bprovided by HGNC Official Full Name RWD domain containing 2Bprovided by HGNC Primary source HGNC:HGNC:1302 See related Ensembl:ENSG00000156253 MIM:617843; AllianceGenome:HGNC:1302 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GL011; C21orf6 Expression Ubiquitous expression in testis (RPKM 9.4), prostate (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
RWDD3, Official Symbol RWDD3provided by HGNC Official Full Name RWD domain containing 3provided by HGNC Primary source HGNC:HGNC:21393 See related Ensembl:ENSG00000122481 MIM:615875; AllianceGenome:HGNC:21393 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RSUME Summary Involved in negative regulation of NF-kappaB transcription factor activity; positive regulation of hypoxia-inducible factor-1alpha signaling pathway; and positive regulation of protein sumoylation. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 8.1), endometrium (RPKM 7.8) and 25 other tissues See more Orthologs mouse all
RWDD4, Official Symbol RWDD4provided by HGNC Official Full Name RWD domain containing 4provided by HGNC Primary source HGNC:HGNC:23750 See related Ensembl:ENSG00000182552 AllianceGenome:HGNC:23750 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM28A; RWDD4A Expression Ubiquitous expression in adrenal (RPKM 29.0), ovary (RPKM 20.4) and 25 other tissues See more Orthologs mouse all
RXFP1, Official Symbol RXFP1provided by HGNC Official Full Name relaxin family peptide receptor 1provided by HGNC Primary source HGNC:HGNC:19718 See related Ensembl:ENSG00000171509 MIM:606654; AllianceGenome:HGNC:19718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LGR7; RXFPR1 Summary This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in brain (RPKM 6.2), endometrium (RPKM 3.9) and 7 other tissues See more Orthologs mouse all
RXFP2, Official Symbol RXFP2provided by HGNC Official Full Name relaxin family peptide receptor 2provided by HGNC Primary source HGNC:HGNC:17318 See related Ensembl:ENSG00000133105 MIM:606655; AllianceGenome:HGNC:17318 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2 Summary This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all
RXFP3, Official Symbol RXFP3provided by HGNC Official Full Name relaxin family peptide receptor 3provided by HGNC Primary source HGNC:HGNC:24883 See related Ensembl:ENSG00000182631 MIM:609445; AllianceGenome:HGNC:24883 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SALPR; RLN3R1; RXFPR3; GPCR135 Summary Predicted to enable G protein-coupled peptide receptor activity. Involved in positive regulation of cytokinesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
RXFP4, Official Symbol RXFP4provided by HGNC Official Full Name relaxin family peptide/INSL5 receptor 4provided by HGNC Primary source HGNC:HGNC:14666 See related Ensembl:ENSG00000173080 MIM:609043; AllianceGenome:HGNC:14666 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR100; RLN3R2; RXFPR4; GPCR142 Summary GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008] Orthologs mouse all
RXRA, Official Symbol RXRAprovided by HGNC Official Full Name retinoid X receptor alphaprovided by HGNC Primary source HGNC:HGNC:10477 See related Ensembl:ENSG00000186350 MIM:180245; AllianceGenome:HGNC:10477 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NR2B1; RXRalpha; RXR-alpha Summary Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] Expression Ubiquitous expression in skin (RPKM 34.2), fat (RPKM 23.2) and 25 other tissues See more Orthologs mouse all
RXRB, Official Symbol RXRBprovided by HGNC Official Full Name retinoid X receptor betaprovided by HGNC Primary source HGNC:HGNC:10478 See related Ensembl:ENSG00000204231 MIM:180246; AllianceGenome:HGNC:10478 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NR2B2; DAUDI6; RCoR-1; RXRbeta; H-2RIIBP; RXR-beta Summary This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in thyroid (RPKM 13.3), spleen (RPKM 12.9) and 25 other tissues See more Orthologs mouse all
RXRG, Official Symbol RXRGprovided by HGNC Official Full Name retinoid X receptor gammaprovided by HGNC Primary source HGNC:HGNC:10479 See related Ensembl:ENSG00000143171 MIM:180247; AllianceGenome:HGNC:10479 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RXRC; NR2B3; RXRgamma; RXR-gamma Summary This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] Expression Broad expression in heart (RPKM 1.5), adrenal (RPKM 1.5) and 22 other tissues See more Orthologs mouse all
RXYLT1, Official Symbol RXYLT1provided by HGNC Official Full Name ribitol xylosyltransferase 1provided by HGNC Primary source HGNC:HGNC:13530 See related Ensembl:ENSG00000118600 MIM:605862; AllianceGenome:HGNC:13530 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TMEM5; HP10481; MDDGA10 Summary This gene encodes a type II transmembrane protein that is thought to have glycosyltransferase function. Mutations in this gene result in cobblestone lissencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] Expression Ubiquitous expression in testis (RPKM 8.9), thyroid (RPKM 7.4) and 25 other tissues See more Orthologs mouse all
RXYLT1-AS1, Official Symbol RXYLT1-AS1provided by HGNC Official Full Name RXYLT1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48910 See related Ensembl:ENSG00000255850 AllianceGenome:HGNC:48910 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TMEM5-AS1 Expression Ubiquitous expression in prostate (RPKM 6.3), testis (RPKM 5.9) and 25 other tissues See more
RYBP, Official Symbol RYBPprovided by HGNC Official Full Name RING1 and YY1 binding proteinprovided by HGNC Primary source HGNC:HGNC:10480 See related Ensembl:ENSG00000163602 MIM:607535; AllianceGenome:HGNC:10480 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAP1; DEDAF; YEAF1; APAP-1 Summary Predicted to enable DNA binding activity and transcription coregulator activity. Involved in several processes, including histone H2A monoubiquitination; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of transcription, DNA-templated. Located in nucleoplasm. Colocalizes with PcG protein complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: suggests misassembly Annotation category: partial on reference assembly Expression Ubiquitous expression in placenta (RPKM 20.7), testis (RPKM 18.4) and 25 other tissues See more Orthologs mouse all
RYK, Official Symbol RYKprovided by HGNC Official Full Name receptor like tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:10481 See related Ensembl:ENSG00000163785 MIM:600524; AllianceGenome:HGNC:10481 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JTK5; RYK1; JTK5A; D3S3195 Summary The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in ovary (RPKM 32.1), testis (RPKM 26.7) and 25 other tissues See more Orthologs mouse all
RYR1, Official Symbol RYR1provided by HGNC Official Full Name ryanodine receptor 1provided by HGNC Primary source HGNC:HGNC:10483 See related Ensembl:ENSG00000196218 MIM:180901; AllianceGenome:HGNC:10483 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCO; KDS; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; CMYP1A; CMYP1B; PPP1R137 Summary This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Broad expression in prostate (RPKM 3.0), esophagus (RPKM 2.5) and 15 other tissues See more Orthologs mouse all
RYR2, Official Symbol RYR2provided by HGNC Official Full Name ryanodine receptor 2provided by HGNC Primary source HGNC:HGNC:10484 See related Ensembl:ENSG00000198626 MIM:180902; AllianceGenome:HGNC:10484 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RyR; ARVC2; ARVD2; RYR-2; VTSIP; VACRDS Summary This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 47.0) and brain (RPKM 4.2) See more Orthologs mouse all
RYR3, Official Symbol RYR3provided by HGNC Official Full Name ryanodine receptor 3provided by HGNC Primary source HGNC:HGNC:10485 See related Ensembl:ENSG00000198838 MIM:180903; AllianceGenome:HGNC:10485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RYR-3; CMYP20 Summary The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Expression Broad expression in brain (RPKM 1.5), endometrium (RPKM 1.4) and 19 other tissues See more Orthologs mouse all
RYR3-DT, Official Symbol RYR3-DTprovided by HGNC Official Full Name RYR3 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:51417 See related Ensembl:ENSG00000259446 AllianceGenome:HGNC:51417 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
S100A1, Official Symbol S100A1provided by HGNC Official Full Name S100 calcium binding protein A1provided by HGNC Primary source HGNC:HGNC:10486 See related Ensembl:ENSG00000160678 MIM:176940; AllianceGenome:HGNC:10486 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S100; S100A; S100-alpha Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 773.3), salivary gland (RPKM 114.1) and 3 other tissues See more Orthologs mouse all
S100A10, Official Symbol S100A10provided by HGNC Official Full Name S100 calcium binding protein A10provided by HGNC Primary source HGNC:HGNC:10487 See related Ensembl:ENSG00000197747 MIM:114085; AllianceGenome:HGNC:10487 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 299.3), esophagus (RPKM 210.9) and 22 other tissues See more Orthologs mouse all
S100A11, Official Symbol S100A11provided by HGNC Official Full Name S100 calcium binding protein A11provided by HGNC Primary source HGNC:HGNC:10488 See related Ensembl:ENSG00000163191 MIM:603114; AllianceGenome:HGNC:10488 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLN70; S100C; HEL-S-43 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 707.5), placenta (RPKM 273.6) and 20 other tissues See more Orthologs mouse all
S100A11P5, Official Symbol S100A11P5provided by HGNC Official Full Name S100A11 pseudogene 5provided by HGNC Primary source HGNC:HGNC:54954 See related Ensembl:ENSG00000238032 AllianceGenome:HGNC:54954 Gene type pseudo RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
S100A11P9, Official Symbol S100A11P9provided by HGNC Official Full Name S100A11 pseudogene 9provided by HGNC Primary source HGNC:HGNC:54958 See related Ensembl:ENSG00000270747 AllianceGenome:HGNC:54958 Gene type pseudo RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
S100A12, Official Symbol S100A12provided by HGNC Official Full Name S100 calcium binding protein A12provided by HGNC Primary source HGNC:HGNC:10489 See related Ensembl:ENSG00000163221 MIM:603112; AllianceGenome:HGNC:10489 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p6; CAGC; CGRP; MRP6; CAAF1; MRP-6; ENRAGE Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014] Expression Restricted expression toward bone marrow (RPKM 747.5) See more Orthologs all
S100A13, Official Symbol S100A13provided by HGNC Official Full Name S100 calcium binding protein A13provided by HGNC Primary source HGNC:HGNC:10490 See related Ensembl:ENSG00000189171 MIM:601989; AllianceGenome:HGNC:10490 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 156.8), fat (RPKM 39.4) and 16 other tissues See more Orthologs mouse all
S100A14, Official Symbol S100A14provided by HGNC Official Full Name S100 calcium binding protein A14provided by HGNC Primary source HGNC:HGNC:18901 See related Ensembl:ENSG00000189334 MIM:607986; AllianceGenome:HGNC:18901 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCMP84; S100A15 Summary This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] Expression Biased expression in esophagus (RPKM 798.1), skin (RPKM 171.2) and 6 other tissues See more Orthologs mouse all
S100A15A, Official Symbol S100A15Aprovided by HGNC Official Full Name S100 calcium binding protein A15A (pseudogene)provided by HGNC Primary source HGNC:HGNC:53871 See related Ensembl:ENSG00000224784 AllianceGenome:HGNC:53871 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
S100A16, Official Symbol S100A16provided by HGNC Official Full Name S100 calcium binding protein A16provided by HGNC Primary source HGNC:HGNC:20441 See related Ensembl:ENSG00000188643 MIM:617437; AllianceGenome:HGNC:20441 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAG13; S100F; DT1P1A7 Summary Enables calcium ion binding activity and protein homodimerization activity. Predicted to act upstream of or within response to calcium ion. Located in several cellular components, including cytosol; extracellular space; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 418.9), skin (RPKM 89.4) and 13 other tissues See more Orthologs mouse all
S100A2, Official Symbol S100A2provided by HGNC Official Full Name S100 calcium binding protein A2provided by HGNC Primary source HGNC:HGNC:10492 See related Ensembl:ENSG00000196754 MIM:176993; AllianceGenome:HGNC:10492 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAN19; S100L Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in esophagus (RPKM 199.3), urinary bladder (RPKM 56.6) and 2 other tissues See more Orthologs all
S100A3, Official Symbol S100A3provided by HGNC Official Full Name S100 calcium binding protein A3provided by HGNC Primary source HGNC:HGNC:10493 See related Ensembl:ENSG00000188015 MIM:176992; AllianceGenome:HGNC:10493 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S100E Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008] Expression Biased expression in lung (RPKM 11.5), skin (RPKM 3.7) and 10 other tissues See more Orthologs mouse all
S100A4, Official Symbol S100A4provided by HGNC Official Full Name S100 calcium binding protein A4provided by HGNC Primary source HGNC:HGNC:10494 See related Ensembl:ENSG00000196154 MIM:114210; AllianceGenome:HGNC:10494 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 268.4), bone marrow (RPKM 235.9) and 21 other tissues See more Orthologs mouse all
S100A5, Official Symbol S100A5provided by HGNC Official Full Name S100 calcium binding protein A5provided by HGNC Primary source HGNC:HGNC:10495 See related Ensembl:ENSG00000196420 MIM:176991; AllianceGenome:HGNC:10495 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S100D Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
S100A6, Official Symbol S100A6provided by HGNC Official Full Name S100 calcium binding protein A6provided by HGNC Primary source HGNC:HGNC:10496 See related Ensembl:ENSG00000197956 MIM:114110; AllianceGenome:HGNC:10496 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2A9; PRA; 5B10; CABP; CACY; S10A6 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 705.5), lung (RPKM 524.4) and 23 other tissues See more Orthologs mouse all
S100A7, Official Symbol S100A7provided by HGNC Official Full Name S100 calcium binding protein A7provided by HGNC Primary source HGNC:HGNC:10497 See related Ensembl:ENSG00000143556 MIM:600353; AllianceGenome:HGNC:10497 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSOR1; S100A7c Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014] Expression Restricted expression toward skin (RPKM 64.2) See more Orthologs all
S100A7A, Official Symbol S100A7Aprovided by HGNC Official Full Name S100 calcium binding protein A7Aprovided by HGNC Primary source HGNC:HGNC:21657 See related Ensembl:ENSG00000184330 MIM:617427; AllianceGenome:HGNC:21657 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NICE2; NICE-2; S100A15; S100A7f; S100A7L1 Summary Enables protein self-association. Predicted to act upstream of or within inflammatory response. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
S100A7P1, Official Symbol S100A7P1provided by HGNC Official Full Name S100 calcium binding protein A7 pseudogene 1provided by HGNC Primary source HGNC:HGNC:21654 See related Ensembl:ENSG00000203781 AllianceGenome:HGNC:21654 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as s100a7d; S100A7L3
S100A8, Official Symbol S100A8provided by HGNC Official Full Name S100 calcium binding protein A8provided by HGNC Primary source HGNC:HGNC:10498 See related Ensembl:ENSG00000143546 MIM:123885; AllianceGenome:HGNC:10498 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P8; MIF; NIF; CAGA; CFAG; CGLA; L1Ag; MRP8; CP-10; MA387; 60B8AG; S100-A8 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] Expression Biased expression in bone marrow (RPKM 3778.8), esophagus (RPKM 2115.4) and 1 other tissue See more Orthologs mouse all
S100A9, Official Symbol S100A9provided by HGNC Official Full Name S100 calcium binding protein A9provided by HGNC Primary source HGNC:HGNC:10499 See related Ensembl:ENSG00000163220 MIM:123886; AllianceGenome:HGNC:10499 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387; S100-A9 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014] Expression Biased expression in bone marrow (RPKM 7440.5), esophagus (RPKM 5956.4) and 1 other tissue See more Orthologs mouse all
S100B, Official Symbol S100Bprovided by HGNC Official Full Name S100 calcium binding protein Bprovided by HGNC Primary source HGNC:HGNC:10500 See related Ensembl:ENSG00000160307 MIM:176990; AllianceGenome:HGNC:10500 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NEF; S100; S100-B; S100beta Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 150.1), fat (RPKM 102.5) and 2 other tissues See more Orthologs mouse all
S100G, Official Symbol S100Gprovided by HGNC Official Full Name S100 calcium binding protein Gprovided by HGNC Primary source HGNC:HGNC:1436 See related Ensembl:ENSG00000169906 MIM:302020; AllianceGenome:HGNC:1436 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CABP; CABP1; CALB3; CABP9K Summary This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles. [provided by RefSeq, Jul 2008] Expression Restricted expression toward duodenum (RPKM 36.4) See more Orthologs mouse all
S100P, Official Symbol S100Pprovided by HGNC Official Full Name S100 calcium binding protein Pprovided by HGNC Primary source HGNC:HGNC:10504 See related Ensembl:ENSG00000163993 MIM:600614; AllianceGenome:HGNC:10504 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIG9 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in stomach (RPKM 580.8), bone marrow (RPKM 258.6) and 4 other tissues See more Orthologs mouse all
S100PBP, Official Symbol S100PBPprovided by HGNC Official Full Name S100P binding proteinprovided by HGNC Primary source HGNC:HGNC:25768 See related Ensembl:ENSG00000116497 MIM:611889; AllianceGenome:HGNC:25768 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S100PBPR Summary This gene encodes a protein that was originally identified by its interaction with S100 calcium-binding protein P. Expression of this protein has been reported to be associated with pancreatic ductal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] Expression Broad expression in testis (RPKM 19.6), lymph node (RPKM 6.5) and 24 other tissues See more Orthologs mouse all
S100Z, Official Symbol S100Zprovided by HGNC Official Full Name S100 calcium binding protein Zprovided by HGNC Primary source HGNC:HGNC:30367 See related Ensembl:ENSG00000171643 MIM:610103; AllianceGenome:HGNC:30367 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Gm625; S100-zeta Summary Members of the S100 protein family contain 2 calcium-binding EF-hands and exhibit cell-type specific expression patterns. For additional background information on S100 proteins, see MIM 114085.[supplied by OMIM, Mar 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all