psui3905/ncbi_genes_summary huggingface dataset:
ZPLD1, Official Symbol ZPLD1provided by HGNC Official Full Name zona pellucida like domain containing 1provided by HGNC Primary source HGNC:HGNC:27022 See related Ensembl:ENSG00000170044 MIM:615915; AllianceGenome:HGNC:27022 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be an extracellular matrix structural constituent. Predicted to act upstream of or within vestibular reflex. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be integral component of membrane. Predicted to be active in cell surface and extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in gall bladder (RPKM 1.4), duodenum (RPKM 0.4) and 5 other tissues See more Orthologs mouse all
ZPLD2P, Official Symbol ZPLD2Pprovided by HGNC Official Full Name zona pellucida like domain containing 2, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54510 See related Ensembl:ENSG00000236155 AllianceGenome:HGNC:54510 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in thyroid (RPKM 4.7), kidney (RPKM 3.3) and 7 other tissues See more
ZPR1, Official Symbol ZPR1provided by HGNC Official Full Name ZPR1 zinc fingerprovided by HGNC Primary source HGNC:HGNC:13051 See related Ensembl:ENSG00000109917 MIM:603901; AllianceGenome:HGNC:13051 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GKAF; ZNF259 Summary The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in testis (RPKM 14.8), bone marrow (RPKM 9.9) and 25 other tissues See more Orthologs mouse all
ZRANB1, Official Symbol ZRANB1provided by HGNC Official Full Name zinc finger RANBP2-type containing 1provided by HGNC Primary source HGNC:HGNC:18224 See related Ensembl:ENSG00000019995 MIM:611749; AllianceGenome:HGNC:18224 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRABID Summary Enables K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent deubiquitinase. Involved in several processes, including positive regulation of Wnt signaling pathway; protein deubiquitination; and regulation of cell morphogenesis. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 10.7), testis (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
ZRANB2, Official Symbol ZRANB2provided by HGNC Official Full Name zinc finger RANBP2-type containing 2provided by HGNC Primary source HGNC:HGNC:13058 See related Ensembl:ENSG00000132485 MIM:604347; AllianceGenome:HGNC:13058 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIS; ZIS1; ZIS2; ZNF265 Summary Enables RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 47.3), lymph node (RPKM 37.7) and 25 other tissues See more Orthologs mouse all
ZRANB2-AS1, Official Symbol ZRANB2-AS1provided by HGNC Official Full Name ZRANB2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43594 See related AllianceGenome:HGNC:43594 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in endometrium (RPKM 22.2), kidney (RPKM 20.0) and 23 other tissues See more
ZRANB3, Official Symbol ZRANB3provided by HGNC Official Full Name zinc finger RANBP2-type containing 3provided by HGNC Primary source HGNC:HGNC:25249 See related Ensembl:ENSG00000121988 MIM:615655; AllianceGenome:HGNC:25249 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AH2; 4933425L19Rik Summary Enables ATP-dependent DNA/DNA annealing activity; K63-linked polyubiquitin modification-dependent protein binding activity; and endodeoxyribonuclease activity. Involved in several processes, including DNA metabolic process; DNA rewinding; and negative regulation of DNA recombination. Located in nuclear replication fork and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 1.8), thyroid (RPKM 0.8) and 24 other tissues See more Orthologs mouse all
ZRSR2, Official Symbol ZRSR2provided by HGNC Official Full Name zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2provided by HGNC Primary source HGNC:HGNC:23019 See related Ensembl:ENSG00000169249 MIM:300028; AllianceGenome:HGNC:23019 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as URP; ZC3H22; U2AF1L2; U2AF1RS2; U2AF1-RS2 Summary This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 3.8), spleen (RPKM 3.5) and 25 other tissues See more Orthologs mouse all
ZRSR2P1, Official Symbol ZRSR2P1provided by HGNC Official Full Name ZRSR2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:12456 See related Ensembl:ENSG00000212643 MIM:601079; AllianceGenome:HGNC:12456 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZRSR1; U2AF1P; ZC3H21; U2AF1L1; U2AFBPL; U2AF1RS1; U2AF1-RS1 Summary Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2AF complex and spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022]
ZSCAN1, Official Symbol ZSCAN1provided by HGNC Official Full Name zinc finger and SCAN domain containing 1provided by HGNC Primary source HGNC:HGNC:23712 See related Ensembl:ENSG00000152467 MIM:620026; AllianceGenome:HGNC:23712 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MZF-1; ZNF915 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
ZSCAN10, Official Symbol ZSCAN10provided by HGNC Official Full Name zinc finger and SCAN domain containing 10provided by HGNC Primary source HGNC:HGNC:12997 See related Ensembl:ENSG00000130182 MIM:618365; AllianceGenome:HGNC:12997 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP206; ZNF206 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZSCAN12, Official Symbol ZSCAN12provided by HGNC Official Full Name zinc finger and SCAN domain containing 12provided by HGNC Primary source HGNC:HGNC:13172 See related Ensembl:ENSG00000158691 MIM:603978; AllianceGenome:HGNC:13172 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP96; ZNF96; ZNF305; ZNF29K1; dJ29K1.2 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 1.8), ovary (RPKM 1.5) and 25 other tissues See more Orthologs mouse all
ZSCAN16, Official Symbol ZSCAN16provided by HGNC Official Full Name zinc finger and SCAN domain containing 16provided by HGNC Primary source HGNC:HGNC:20813 See related Ensembl:ENSG00000196812 MIM:618544; AllianceGenome:HGNC:20813 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF392; ZNF435; dJ265C24.3 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 2.1), small intestine (RPKM 2.0) and 25 other tissues See more Orthologs all
ZSCAN16-AS1, Official Symbol ZSCAN16-AS1provided by HGNC Official Full Name ZSCAN16 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48982 See related Ensembl:ENSG00000269293 AllianceGenome:HGNC:48982 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in kidney (RPKM 2.3), thyroid (RPKM 2.1) and 25 other tissues See more
ZSCAN18, Official Symbol ZSCAN18provided by HGNC Official Full Name zinc finger and SCAN domain containing 18provided by HGNC Primary source HGNC:HGNC:21037 See related Ensembl:ENSG00000121413 AllianceGenome:HGNC:21037 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF447 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 14.7), endometrium (RPKM 11.3) and 25 other tissues See more Orthologs mouse all
ZSCAN2, Official Symbol ZSCAN2provided by HGNC Official Full Name zinc finger and SCAN domain containing 2provided by HGNC Primary source HGNC:HGNC:20994 See related Ensembl:ENSG00000176371 AllianceGenome:HGNC:20994 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP29; ZNF854 Summary The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 2.7), testis (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
ZSCAN20, Official Symbol ZSCAN20provided by HGNC Official Full Name zinc finger and SCAN domain containing 20provided by HGNC Primary source HGNC:HGNC:13093 See related Ensembl:ENSG00000121903 MIM:611315; AllianceGenome:HGNC:13093 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX29; ZNF31; ZFP-31; ZNF360 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZSCAN21, Official Symbol ZSCAN21provided by HGNC Official Full Name zinc finger and SCAN domain containing 21provided by HGNC Primary source HGNC:HGNC:13104 See related Ensembl:ENSG00000166529 MIM:601261; AllianceGenome:HGNC:13104 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF38; Zipro1; NY-REN-21 Summary Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 4.9), endometrium (RPKM 3.1) and 25 other tissues See more Orthologs mouse all
ZSCAN22, Official Symbol ZSCAN22provided by HGNC Official Full Name zinc finger and SCAN domain containing 22provided by HGNC Primary source HGNC:HGNC:4929 See related Ensembl:ENSG00000182318 MIM:165260; AllianceGenome:HGNC:4929 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HKR2; ZNF50 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZSCAN23, Official Symbol ZSCAN23provided by HGNC Official Full Name zinc finger and SCAN domain containing 23provided by HGNC Primary source HGNC:HGNC:21193 See related Ensembl:ENSG00000187987 AllianceGenome:HGNC:21193 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF390; ZNF453; dJ29K1.3; dJ29K1.3.1 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
ZSCAN25, Official Symbol ZSCAN25provided by HGNC Official Full Name zinc finger and SCAN domain containing 25provided by HGNC Primary source HGNC:HGNC:21961 See related Ensembl:ENSG00000197037 AllianceGenome:HGNC:21961 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF498 Summary This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in small intestine (RPKM 5.1), duodenum (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
ZSCAN26, Official Symbol ZSCAN26provided by HGNC Official Full Name zinc finger and SCAN domain containing 26provided by HGNC Primary source HGNC:HGNC:12978 See related Ensembl:ENSG00000197062 MIM:616474; AllianceGenome:HGNC:12978 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SREZBP; ZNF187; SRE-ZBP Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 10.1), endometrium (RPKM 7.8) and 25 other tissues See more Orthologs mouse all
ZSCAN29, Official Symbol ZSCAN29provided by HGNC Official Full Name zinc finger and SCAN domain containing 29provided by HGNC Primary source HGNC:HGNC:26673 See related Ensembl:ENSG00000140265 AllianceGenome:HGNC:26673 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF690; Zfp690 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 6.9), lymph node (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
ZSCAN30, Official Symbol ZSCAN30provided by HGNC Official Full Name zinc finger and SCAN domain containing 30provided by HGNC Primary source HGNC:HGNC:33517 See related Ensembl:ENSG00000186814 AllianceGenome:HGNC:33517 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF917; ZNF-WYM; ZNF397OS Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.9), brain (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
ZSCAN31, Official Symbol ZSCAN31provided by HGNC Official Full Name zinc finger and SCAN domain containing 31provided by HGNC Primary source HGNC:HGNC:14097 See related Ensembl:ENSG00000235109 MIM:610794; AllianceGenome:HGNC:14097 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF323; ZNF310P; ZNF20-Lp Summary This gene encodes a protein containing multiple C2H2-type zinc finger motifs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in ovary (RPKM 2.2), testis (RPKM 2.1) and 25 other tissues See more Orthologs all
ZSCAN32, Official Symbol ZSCAN32provided by HGNC Official Full Name zinc finger and SCAN domain containing 32provided by HGNC Primary source HGNC:HGNC:20812 See related Ensembl:ENSG00000140987 AllianceGenome:HGNC:20812 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCCS-5; ZNF434 Summary Enables identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 4.7), lymph node (RPKM 4.2) and 25 other tissues See more Orthologs all
ZSCAN4, Official Symbol ZSCAN4provided by HGNC Official Full Name zinc finger and SCAN domain containing 4provided by HGNC Primary source HGNC:HGNC:23709 See related Ensembl:ENSG00000180532 MIM:613419; AllianceGenome:HGNC:23709 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF494 Summary The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010] Expression Low expression observed in reference dataset See more Orthologs all
ZSCAN5A, Official Symbol ZSCAN5Aprovided by HGNC Official Full Name zinc finger and SCAN domain containing 5Aprovided by HGNC Primary source HGNC:HGNC:23710 See related Ensembl:ENSG00000131848 AllianceGenome:HGNC:23710 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF495; ZSCAN5 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 6.0), kidney (RPKM 0.7) and 21 other tissues See more Orthologs all
ZSCAN5B, Official Symbol ZSCAN5Bprovided by HGNC Official Full Name zinc finger and SCAN domain containing 5Bprovided by HGNC Primary source HGNC:HGNC:34246 See related Ensembl:ENSG00000197213 AllianceGenome:HGNC:34246 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF371; ZNF495B Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 1.5) and prostate (RPKM 0.1) See more Orthologs all
ZSCAN5C, Official Symbol ZSCAN5Cprovided by HGNC Official Full Name zinc finger and SCAN domain containing 5Cprovided by HGNC Primary source HGNC:HGNC:34294 See related Ensembl:ENSG00000204532 AllianceGenome:HGNC:34294 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF495C; ZSCAN5CP Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
ZSCAN5DP, Official Symbol ZSCAN5DPprovided by HGNC Official Full Name zinc finger and SCAN domain containing 5D pseudogeneprovided by HGNC Primary source HGNC:HGNC:37706 See related Ensembl:ENSG00000267908 AllianceGenome:HGNC:37706 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF495D; ZSCAN5D Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
ZSCAN9, Official Symbol ZSCAN9provided by HGNC Official Full Name zinc finger and SCAN domain containing 9provided by HGNC Primary source HGNC:HGNC:12984 See related Ensembl:ENSG00000137185 MIM:602246; AllianceGenome:HGNC:12984 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRD51; ZNF193 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.8), endometrium (RPKM 3.5) and 25 other tissues See more Orthologs all
ZSWIM1, Official Symbol ZSWIM1provided by HGNC Official Full Name zinc finger SWIM-type containing 1provided by HGNC Primary source HGNC:HGNC:16155 See related Ensembl:ENSG00000168612 AllianceGenome:HGNC:16155 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf162 Summary Predicted to enable zinc ion binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 3.0), testis (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
ZSWIM2, Official Symbol ZSWIM2provided by HGNC Official Full Name zinc finger SWIM-type containing 2provided by HGNC Primary source HGNC:HGNC:30990 See related Ensembl:ENSG00000163012 AllianceGenome:HGNC:30990 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEX; ZZZ2 Summary Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in apoptotic process and protein polyubiquitination. Predicted to act upstream of or within positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 5.3) See more Orthologs mouse all
ZSWIM3, Official Symbol ZSWIM3provided by HGNC Official Full Name zinc finger SWIM-type containing 3provided by HGNC Primary source HGNC:HGNC:16157 See related Ensembl:ENSG00000132801 MIM:620336; AllianceGenome:HGNC:16157 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPP1R174; C20orf164 Summary Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.2), lymph node (RPKM 1.8) and 25 other tissues See more Orthologs mouse all
ZSWIM4, Official Symbol ZSWIM4provided by HGNC Official Full Name zinc finger SWIM-type containing 4provided by HGNC Primary source HGNC:HGNC:25704 See related Ensembl:ENSG00000132003 AllianceGenome:HGNC:25704 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable zinc ion binding activity. Predicted to be part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 2.3), lung (RPKM 2.0) and 25 other tissues See more Orthologs mouse all
ZSWIM5, Official Symbol ZSWIM5provided by HGNC Official Full Name zinc finger SWIM-type containing 5provided by HGNC Primary source HGNC:HGNC:29299 See related Ensembl:ENSG00000162415 MIM:620132; AllianceGenome:HGNC:29299 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable zinc ion binding activity. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in adrenal (RPKM 5.6), ovary (RPKM 4.2) and 22 other tissues See more Orthologs mouse all
ZSWIM5P1, Official Symbol ZSWIM5P1provided by HGNC Official Full Name zinc finger SWIM-type containing 5 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43768 See related Ensembl:ENSG00000235430 AllianceGenome:HGNC:43768 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZSWIM6, Official Symbol ZSWIM6provided by HGNC Official Full Name zinc finger SWIM-type containing 6provided by HGNC Primary source HGNC:HGNC:29316 See related Ensembl:ENSG00000130449 MIM:615951; AllianceGenome:HGNC:29316 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFND; NEDMAGA Summary The protein encoded by this gene contains a zinc finger SWI2/SNF2 and MuDR (SWIM) domain. Proteins with SWIM domains have been found in a diverse number of species and are predicted to interact with DNA or proteins. Mutations in this gene result in acromelic frontonasal dysostosis. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in gall bladder (RPKM 6.8), brain (RPKM 6.4) and 25 other tissues See more Orthologs mouse all
ZSWIM7, Official Symbol ZSWIM7provided by HGNC Official Full Name zinc finger SWIM-type containing 7provided by HGNC Primary source HGNC:HGNC:26993 See related Ensembl:ENSG00000214941 MIM:614535; AllianceGenome:HGNC:26993 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SWS1; ODG10; SPGF71 Summary Predicted to enable zinc ion binding activity. Involved in double-strand break repair via homologous recombination and protein stabilization. Part of Shu complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 6.2), adrenal (RPKM 6.1) and 25 other tissues See more Orthologs mouse all
ZSWIM8, Official Symbol ZSWIM8provided by HGNC Official Full Name zinc finger SWIM-type containing 8provided by HGNC Primary source HGNC:HGNC:23528 See related Ensembl:ENSG00000214655 MIM:619213; AllianceGenome:HGNC:23528 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA0913 Summary Enables ubiquitin ligase-substrate adaptor activity. Involved in positive regulation of miRNA catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 21.6), spleen (RPKM 16.0) and 25 other tissues See more Orthologs mouse all
ZSWIM8-AS1, Official Symbol ZSWIM8-AS1provided by HGNC Official Full Name ZSWIM8 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:45103 See related Ensembl:ENSG00000272589 AllianceGenome:HGNC:45103 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in testis (RPKM 22.4), spleen (RPKM 16.4) and 25 other tissues See more
ZSWIM9, Official Symbol ZSWIM9provided by HGNC Official Full Name zinc finger SWIM-type containing 9provided by HGNC Primary source HGNC:HGNC:34495 See related Ensembl:ENSG00000185453 AllianceGenome:HGNC:34495 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C19orf68 Summary Predicted to act upstream of or within hematopoietic progenitor cell differentiation. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 3.0), fat (RPKM 2.3) and 25 other tissues See more Orthologs mouse all
ZUP1, Official Symbol ZUP1provided by HGNC Official Full Name zinc finger containing ubiquitin peptidase 1provided by HGNC Primary source HGNC:HGNC:21224 See related Ensembl:ENSG00000153975 AllianceGenome:HGNC:21224 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUB; ZUFSP; C6orf113 Summary This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018] Expression Ubiquitous expression in duodenum (RPKM 4.7), bone marrow (RPKM 4.6) and 25 other tissues See more Orthologs mouse all
ZW10, Official Symbol ZW10provided by HGNC Official Full Name zw10 kinetochore proteinprovided by HGNC Primary source HGNC:HGNC:13194 See related Ensembl:ENSG00000086827 MIM:603954; AllianceGenome:HGNC:13194 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HZW10; KNTC1AP Summary This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in testis (RPKM 9.8), skin (RPKM 6.7) and 25 other tissues See more Orthologs mouse all
ZWILCH, Official Symbol ZWILCHprovided by HGNC Official Full Name zwilch kinetochore proteinprovided by HGNC Primary source HGNC:HGNC:25468 See related Ensembl:ENSG00000174442 MIM:609984; AllianceGenome:HGNC:25468 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KNTC1AP; hZwilch Summary Involved in protein localization to kinetochore. Located in kinetochore. Part of RZZ complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 32.5), lymph node (RPKM 6.0) and 19 other tissues See more Orthologs mouse all
ZWINT, Official Symbol ZWINTprovided by HGNC Official Full Name ZW10 interacting kinetochore proteinprovided by HGNC Primary source HGNC:HGNC:13195 See related Ensembl:ENSG00000122952 MIM:609177; AllianceGenome:HGNC:13195 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIP30; ZWINT1; KNTC2AP; HZwint-1 Summary This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 17.2), testis (RPKM 16.4) and 21 other tissues See more Orthologs mouse all
ZXDA, Official Symbol ZXDAprovided by HGNC Official Full Name zinc finger X-linked duplicated Aprovided by HGNC Primary source HGNC:HGNC:13198 See related Ensembl:ENSG00000198205 MIM:300235; AllianceGenome:HGNC:13198 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF896 Summary This gene encodes one of two duplicated zinc finger genes on chromosome Xp11. This gene is the telomeric copy; GeneID 158586 ZXDB is the more centromeric copy. The two genes have 98% nucleotide sequence similarity, and the predicted proteins contain 10 tandem zinc finger motifs. [provided by RefSeq, Nov 2009] Orthologs all
ZXDB, Official Symbol ZXDBprovided by HGNC Official Full Name zinc finger X-linked duplicated Bprovided by HGNC Primary source HGNC:HGNC:13199 See related Ensembl:ENSG00000198455 MIM:300236; AllianceGenome:HGNC:13199 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF905; dJ83L6.1 Summary The ZXDB gene is one of a pair of duplicated zinc finger genes on chromosome Xp11.21 (Greig et al., 1993 [PubMed 8268913]); see also ZXDA (MIM 300235).[supplied by OMIM, Jul 2010] Orthologs all
ZXDC, Official Symbol ZXDCprovided by HGNC Official Full Name ZXD family zinc finger Cprovided by HGNC Primary source HGNC:HGNC:28160 See related Ensembl:ENSG00000070476 MIM:615746; AllianceGenome:HGNC:28160 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZXDL Summary Enables C2H2 zinc finger domain binding activity; LRR domain binding activity; and transcription coactivator activity. Involved in positive regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 13.7), spleen (RPKM 5.6) and 25 other tissues See more Orthologs mouse all
ZYG11A, Official Symbol ZYG11Aprovided by HGNC Official Full Name zyg-11 family member A, cell cycle regulatorprovided by HGNC Primary source HGNC:HGNC:32058 See related Ensembl:ENSG00000203995 MIM:618675; AllianceGenome:HGNC:32058 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZYG11 Summary Predicted to be part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 2.3), thyroid (RPKM 1.5) and 6 other tissues See more Orthologs mouse all
ZYG11B, Official Symbol ZYG11Bprovided by HGNC Official Full Name zyg-11 family member B, cell cycle regulatorprovided by HGNC Primary source HGNC:HGNC:25820 See related Ensembl:ENSG00000162378 MIM:618673; AllianceGenome:HGNC:25820 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZYG11 Summary Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 12.1), thyroid (RPKM 8.7) and 25 other tissues See more Orthologs mouse all
ZYX, Official Symbol ZYXprovided by HGNC Official Full Name zyxinprovided by HGNC Primary source HGNC:HGNC:13200 See related Ensembl:ENSG00000159840 MIM:602002; AllianceGenome:HGNC:13200 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ESP-2; HED-2 Summary Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 122.6), lung (RPKM 100.3) and 25 other tissues See more Orthologs mouse all
ZYXP1, Official Symbol ZYXP1provided by HGNC Official Full Name zyxin pseudogene 1provided by HGNC Primary source HGNC:HGNC:51695 See related Ensembl:ENSG00000274572 AllianceGenome:HGNC:51695 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZZEF1, Official Symbol ZZEF1provided by HGNC Official Full Name zinc finger ZZ-type and EF-hand domain containing 1provided by HGNC Primary source HGNC:HGNC:29027 See related Ensembl:ENSG00000074755 MIM:619459; AllianceGenome:HGNC:29027 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZZZ4 Summary Predicted to enable ubiquitin-like protein ligase activity. Predicted to act upstream of or within several processes, including glutamatergic synaptic transmission; regulation of peptidyl-tyrosine phosphorylation; and visual learning. Predicted to be located in cell surface; postsynapse; and presynaptic active zone. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in small intestine (RPKM 12.0), colon (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
ZZZ3, Official Symbol ZZZ3provided by HGNC Official Full Name zinc finger ZZ-type containing 3provided by HGNC Primary source HGNC:HGNC:24523 See related Ensembl:ENSG00000036549 MIM:619892; AllianceGenome:HGNC:24523 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATAC1 Summary Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in histone H4 acetylation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 9.6), ovary (RPKM 6.7) and 25 other tissues See more Orthologs mouse all