psui3905/ncbi_genes_summary huggingface dataset:
SLC25A5-AS1, Official Symbol SLC25A5-AS1provided by HGNC Official Full Name SLC25A5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43438 See related Ensembl:ENSG00000224281 AllianceGenome:HGNC:43438 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in kidney (RPKM 1.4), thyroid (RPKM 1.4) and 25 other tissues See more
SLC25A51, Official Symbol SLC25A51provided by HGNC Official Full Name solute carrier family 25 member 51provided by HGNC Primary source HGNC:HGNC:23323 See related Ensembl:ENSG00000122696 MIM:619153; AllianceGenome:HGNC:23323 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CG7943; MCART1 Summary Enables NAD transmembrane transporter activity. Involved in mitochondrial NAD transmembrane transport. Located in mitochondrion. Is active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 3.6), testis (RPKM 1.8) and 25 other tissues See more Orthologs mouse all
SLC25A51P2, Official Symbol SLC25A51P2provided by HGNC Official Full Name SLC25A51 pseudogene 2provided by HGNC Primary source HGNC:HGNC:23327 See related Ensembl:ENSG00000263716 AllianceGenome:HGNC:23327 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCART4P
SLC25A51P3, Official Symbol SLC25A51P3provided by HGNC Official Full Name SLC25A51 pseudogene 3provided by HGNC Primary source HGNC:HGNC:31051 See related AllianceGenome:HGNC:31051 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCART5P
SLC25A52, Official Symbol SLC25A52provided by HGNC Official Full Name solute carrier family 25 member 52provided by HGNC Primary source HGNC:HGNC:23324 See related Ensembl:ENSG00000141437 MIM:616153; AllianceGenome:HGNC:23324 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCART2 Summary This gene is similar to the mitochondrial carrier triple repeat 1 gene on chromosome 9. The gene is intronless and may be an evolving pseudogene; however, it is transcribed and it contains a full-length coding region so it is currently classified as a protein-coding locus. [provided by RefSeq, Jul 2008] Orthologs all
SLC25A53, Official Symbol SLC25A53provided by HGNC Official Full Name solute carrier family 25 member 53provided by HGNC Primary source HGNC:HGNC:31894 See related Ensembl:ENSG00000269743 MIM:300941; AllianceGenome:HGNC:31894 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCART6 Summary Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
SLC25A5P1, Official Symbol SLC25A5P1provided by HGNC Official Full Name solute carrier family 25 member 5 pseudogene 1provided by HGNC Primary source HGNC:HGNC:19250 See related AllianceGenome:HGNC:19250 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANTP3; bK250D10.4
SLC25A5P2, Official Symbol SLC25A5P2provided by HGNC Official Full Name solute carrier family 25 member 5 pseudogene 2provided by HGNC Primary source HGNC:HGNC:35470 See related AllianceGenome:HGNC:35470 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A5P4, Official Symbol SLC25A5P4provided by HGNC Official Full Name solute carrier family 25 member 5 pseudogene 4provided by HGNC Primary source HGNC:HGNC:35471 See related AllianceGenome:HGNC:35471 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A5P5, Official Symbol SLC25A5P5provided by HGNC Official Full Name solute carrier family 25 member 5 pseudogene 5provided by HGNC Primary source HGNC:HGNC:511 See related Ensembl:ENSG00000226421 AllianceGenome:HGNC:511 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANTP5; TCAG_29001
SLC25A5P6, Official Symbol SLC25A5P6provided by HGNC Official Full Name solute carrier family 25 member 5 pseudogene 6provided by HGNC Primary source HGNC:HGNC:512 See related AllianceGenome:HGNC:512 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANTP6
SLC25A6, Official Symbol SLC25A6provided by HGNC Official Full Name solute carrier family 25 member 6provided by HGNC Primary source HGNC:HGNC:10992 See related Ensembl:ENSG00000169100 Ensembl:ENSG00000292334 MIM:300151; MIM:403000; AllianceGenome:HGNC:10992 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y Summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013] Expression Ubiquitous expression in kidney (RPKM 238.9), ovary (RPKM 226.6) and 25 other tissues See more Orthologs all
SLC25A6P1, Official Symbol SLC25A6P1provided by HGNC Official Full Name solute carrier family 25 member 6 pseudogene 1provided by HGNC Primary source HGNC:HGNC:16554 See related Ensembl:ENSG00000233015 AllianceGenome:HGNC:16554 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLC25A5L; dJ1065O2.2
SLC25A6P3, Official Symbol SLC25A6P3provided by HGNC Official Full Name solute carrier family 25 member 6 pseudogene 3provided by HGNC Primary source HGNC:HGNC:43852 See related Ensembl:ENSG00000232846 AllianceGenome:HGNC:43852 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A6P4, Official Symbol SLC25A6P4provided by HGNC Official Full Name solute carrier family 25 member 6 pseudogene 4provided by HGNC Primary source HGNC:HGNC:43853 See related Ensembl:ENSG00000266909 AllianceGenome:HGNC:43853 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A6P5, Official Symbol SLC25A6P5provided by HGNC Official Full Name solute carrier family 25 member 6 pseudogene 5provided by HGNC Primary source HGNC:HGNC:43854 See related AllianceGenome:HGNC:43854 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A6P6, Official Symbol SLC25A6P6provided by HGNC Official Full Name solute carrier family 25 member 6 pseudogene 6provided by HGNC Primary source HGNC:HGNC:43855 See related Ensembl:ENSG00000218870 AllianceGenome:HGNC:43855 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC26A1, Official Symbol SLC26A1provided by HGNC Official Full Name solute carrier family 26 member 1provided by HGNC Primary source HGNC:HGNC:10993 See related Ensembl:ENSG00000145217 MIM:610130; AllianceGenome:HGNC:10993 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAON; EDM4; SAT1; CAON1; SAT-1; HYSULF Summary This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 6.4), liver (RPKM 1.9) and 19 other tissues See more Orthologs mouse all
SLC26A11, Official Symbol SLC26A11provided by HGNC Official Full Name solute carrier family 26 member 11provided by HGNC Primary source HGNC:HGNC:14471 See related Ensembl:ENSG00000181045 MIM:610117; AllianceGenome:HGNC:14471 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] Expression Ubiquitous expression in adrenal (RPKM 8.3), spleen (RPKM 6.4) and 25 other tissues See more Orthologs mouse all
SLC26A2, Official Symbol SLC26A2provided by HGNC Official Full Name solute carrier family 26 member 2provided by HGNC Primary source HGNC:HGNC:10994 See related Ensembl:ENSG00000155850 MIM:606718; AllianceGenome:HGNC:10994 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DTD; EDM4; DTDST; MST153; D5S1708; MSTP157 Summary The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 149.1), adrenal (RPKM 20.2) and 3 other tissues See more Orthologs mouse all
SLC26A3, Official Symbol SLC26A3provided by HGNC Official Full Name solute carrier family 26 member 3provided by HGNC Primary source HGNC:HGNC:3018 See related Ensembl:ENSG00000091138 MIM:126650; AllianceGenome:HGNC:3018 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLD; DRA Summary The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008] Expression Biased expression in colon (RPKM 709.1), duodenum (RPKM 299.0) and 1 other tissue See more Orthologs mouse all
SLC26A4, Official Symbol SLC26A4provided by HGNC Official Full Name solute carrier family 26 member 4provided by HGNC Primary source HGNC:HGNC:8818 See related Ensembl:ENSG00000091137 MIM:605646; AllianceGenome:HGNC:8818 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EVA; PDS; DFNB4; TDH2B Summary Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. [provided by RefSeq, Jul 2008] Expression Restricted expression toward thyroid (RPKM 117.6) See more Orthologs mouse all
SLC26A5, Official Symbol SLC26A5provided by HGNC Official Full Name solute carrier family 26 member 5provided by HGNC Primary source HGNC:HGNC:9359 See related Ensembl:ENSG00000170615 MIM:604943; AllianceGenome:HGNC:9359 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRES; DFNB61 Summary This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009] Expression Ubiquitous expression in adrenal (RPKM 1.9), kidney (RPKM 1.8) and 25 other tissues See more Orthologs mouse all
SLC26A6, Official Symbol SLC26A6provided by HGNC Official Full Name solute carrier family 26 member 6provided by HGNC Primary source HGNC:HGNC:14472 See related Ensembl:ENSG00000225697 MIM:610068; AllianceGenome:HGNC:14472 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in colon (RPKM 11.7), bone marrow (RPKM 8.2) and 25 other tissues See more Orthologs mouse all
SLC26A7, Official Symbol SLC26A7provided by HGNC Official Full Name solute carrier family 26 member 7provided by HGNC Primary source HGNC:HGNC:14467 See related Ensembl:ENSG00000147606 MIM:608479; AllianceGenome:HGNC:14467 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SUT2 Summary This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013] Expression Restricted expression toward thyroid (RPKM 194.6) See more Orthologs mouse all
SLC26A8, Official Symbol SLC26A8provided by HGNC Official Full Name solute carrier family 26 member 8provided by HGNC Primary source HGNC:HGNC:14468 See related Ensembl:ENSG00000112053 MIM:608480; AllianceGenome:HGNC:14468 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AZON; TAT1; SPGF3 Summary This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010] Expression Restricted expression toward testis (RPKM 27.9) See more Orthologs mouse all
SLC26A9, Official Symbol SLC26A9provided by HGNC Official Full Name solute carrier family 26 member 9provided by HGNC Primary source HGNC:HGNC:14469 See related Ensembl:ENSG00000174502 MIM:608481; AllianceGenome:HGNC:14469 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008] Expression Biased expression in salivary gland (RPKM 19.0), stomach (RPKM 12.3) and 5 other tissues See more Orthologs mouse all
SLC27A1, Official Symbol SLC27A1provided by HGNC Official Full Name solute carrier family 27 member 1provided by HGNC Primary source HGNC:HGNC:10995 See related Ensembl:ENSG00000130304 MIM:600691; AllianceGenome:HGNC:10995 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FATP; FATP1; ACSVL5; FATP-1 Summary Enables biotin transmembrane transporter activity; efflux transmembrane transporter activity; and long-chain fatty acid transporter activity. Involved in several processes, including carboxylic acid transmembrane transport; glycerophospholipid biosynthetic process; and lipid transport across blood-brain barrier. Located in membrane. Part of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 10.2), fat (RPKM 9.1) and 24 other tissues See more Orthologs mouse all
SLC27A2, Official Symbol SLC27A2provided by HGNC Official Full Name solute carrier family 27 member 2provided by HGNC Primary source HGNC:HGNC:10996 See related Ensembl:ENSG00000140284 MIM:603247; AllianceGenome:HGNC:10996 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VLCS; FATP2; VLACS; ACSVL1; FACVL1; hFACVL1; HsT17226 Summary The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] Expression Biased expression in liver (RPKM 63.2), kidney (RPKM 62.8) and 5 other tissues See more Orthologs mouse all
SLC27A3, Official Symbol SLC27A3provided by HGNC Official Full Name solute carrier family 27 member 3provided by HGNC Primary source HGNC:HGNC:10997 See related Ensembl:ENSG00000143554 MIM:604193; AllianceGenome:HGNC:10997 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FATP3; ACSVL3; VLCS-3 Summary This gene belongs to a family of integral membrane proteins and encodes a protein that is involved in lipid metabolism. The increased expression of this gene in human neural stem cells derived from induced pluripotent stem cells suggests that it plays an important role in early brain development. Naturally occurring mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in lung (RPKM 12.3), fat (RPKM 11.5) and 25 other tissues See more Orthologs mouse all
SLC27A4, Official Symbol SLC27A4provided by HGNC Official Full Name solute carrier family 27 member 4provided by HGNC Primary source HGNC:HGNC:10998 See related Ensembl:ENSG00000167114 MIM:604194; AllianceGenome:HGNC:10998 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IPS; FATP4; ACSVL4 Summary This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010] Expression Broad expression in duodenum (RPKM 32.2), small intestine (RPKM 21.2) and 24 other tissues See more Orthologs mouse all
SLC27A5, Official Symbol SLC27A5provided by HGNC Official Full Name solute carrier family 27 member 5provided by HGNC Primary source HGNC:HGNC:10999 See related Ensembl:ENSG00000083807 MIM:603314; AllianceGenome:HGNC:10999 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BAL; ACSB; BACS; FATP5; ACSVL6; FACVL3; FATP-5; VLACSR; VLCSH2; VLCS-H2 Summary The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 126.6) and testis (RPKM 2.0) See more Orthologs mouse all
SLC27A6, Official Symbol SLC27A6provided by HGNC Official Full Name solute carrier family 27 member 6provided by HGNC Primary source HGNC:HGNC:11000 See related Ensembl:ENSG00000113396 MIM:604196; AllianceGenome:HGNC:11000 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FATP6; ACSVL2; FACVL2; VLCS-H1 Summary This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 12.7), heart (RPKM 7.8) and 8 other tissues See more Orthologs mouse all
SLC28A1, Official Symbol SLC28A1provided by HGNC Official Full Name solute carrier family 28 member 1provided by HGNC Primary source HGNC:HGNC:11001 See related Ensembl:ENSG00000156222 MIM:606207; AllianceGenome:HGNC:11001 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNT1; HCNT1; URCTU Summary Enables azole transmembrane transporter activity; cytidine transmembrane transporter activity; and uridine transmembrane transporter activity. Involved in azole transmembrane transport; nucleoside transport; and pyrimidine-containing compound transmembrane transport. Located in cytosol; nuclear speck; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 9.5), small intestine (RPKM 9.4) and 2 other tissues See more Orthologs mouse all
SLC28A2, Official Symbol SLC28A2provided by HGNC Official Full Name solute carrier family 28 member 2provided by HGNC Primary source HGNC:HGNC:11002 See related Ensembl:ENSG00000137860 MIM:606208; AllianceGenome:HGNC:11002 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNT2; HCNT2; SPNT1; HsT17153 Summary Enables neurotransmitter transmembrane transporter activity and nucleoside transmembrane transporter activity. Involved in several processes, including nucleoside transport; purine nucleobase transmembrane transport; and pyrimidine-containing compound transmembrane transport. Predicted to be located in membrane. Predicted to be part of brush border membrane; coated vesicle; and vesicle membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in small intestine (RPKM 43.4), duodenum (RPKM 31.3) and 4 other tissues See more Orthologs all
SLC28A3, Official Symbol SLC28A3provided by HGNC Official Full Name solute carrier family 28 member 3provided by HGNC Primary source HGNC:HGNC:16484 See related Ensembl:ENSG00000197506 MIM:608269; AllianceGenome:HGNC:16484 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNT3 Summary Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008] Expression Biased expression in gall bladder (RPKM 4.2), bone marrow (RPKM 3.2) and 11 other tissues See more Orthologs mouse all
SLC29A1, Official Symbol SLC29A1provided by HGNC Official Full Name solute carrier family 29 member 1 (Augustine blood group)provided by HGNC Primary source HGNC:HGNC:11003 See related Ensembl:ENSG00000112759 MIM:602193; AllianceGenome:HGNC:11003 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AUG; ENT1; hENT1 Summary This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 38.0), fat (RPKM 34.4) and 25 other tissues See more Orthologs mouse all
SLC29A2, Official Symbol SLC29A2provided by HGNC Official Full Name solute carrier family 29 member 2provided by HGNC Primary source HGNC:HGNC:11004 See related Ensembl:ENSG00000174669 MIM:602110; AllianceGenome:HGNC:11004 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENT2; DER12; HNP36; hENT2 Summary The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] Expression Ubiquitous expression in duodenum (RPKM 6.4), small intestine (RPKM 4.5) and 23 other tissues See more Orthologs mouse all
SLC29A3, Official Symbol SLC29A3provided by HGNC Official Full Name solute carrier family 29 member 3provided by HGNC Primary source HGNC:HGNC:23096 See related Ensembl:ENSG00000198246 MIM:612373; AllianceGenome:HGNC:23096 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENT3; HJCD; PHID; HCLAP Summary This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010] Expression Ubiquitous expression in placenta (RPKM 7.5), urinary bladder (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
SLC29A4, Official Symbol SLC29A4provided by HGNC Official Full Name solute carrier family 29 member 4provided by HGNC Primary source HGNC:HGNC:23097 See related Ensembl:ENSG00000164638 MIM:609149; AllianceGenome:HGNC:23097 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENT4; PMAT Summary This gene encodes a member of the SLC29A/ENT transporter protein family. The encoded membrane protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Biased expression in fat (RPKM 35.4), adrenal (RPKM 3.7) and 4 other tissues See more Orthologs mouse all
SLC29A4P1, Official Symbol SLC29A4P1provided by HGNC Official Full Name solute carrier family 29 member 4 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43783 See related Ensembl:ENSG00000214668 AllianceGenome:HGNC:43783 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC29A4P2, Official Symbol SLC29A4P2provided by HGNC Official Full Name solute carrier family 29 member 4 pseudogene 2provided by HGNC Primary source HGNC:HGNC:43782 See related Ensembl:ENSG00000214660 AllianceGenome:HGNC:43782 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC2A1, Official Symbol SLC2A1provided by HGNC Official Full Name solute carrier family 2 member 1provided by HGNC Primary source HGNC:HGNC:11005 See related Ensembl:ENSG00000117394 MIM:138140; AllianceGenome:HGNC:11005 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSE; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS Summary This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013] Expression Biased expression in placenta (RPKM 289.6), skin (RPKM 60.0) and 6 other tissues See more Orthologs mouse all
SLC2A10, Official Symbol SLC2A10provided by HGNC Official Full Name solute carrier family 2 member 10provided by HGNC Primary source HGNC:HGNC:13444 See related Ensembl:ENSG00000197496 MIM:606145; AllianceGenome:HGNC:13444 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATS; ATORS; GLUT10 Summary This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009] Expression Broad expression in prostate (RPKM 8.3), thyroid (RPKM 6.7) and 24 other tissues See more Orthologs mouse all
SLC2A11, Official Symbol SLC2A11provided by HGNC Official Full Name solute carrier family 2 member 11provided by HGNC Primary source HGNC:HGNC:14239 See related Ensembl:ENSG00000133460 MIM:610367; AllianceGenome:HGNC:14239 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT10; GLUT11 Summary This gene belongs to a family of proteins that mediate the transport of sugars across the cell membrane. The encoded protein transports glucose and fructose. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in kidney (RPKM 6.0), brain (RPKM 3.5) and 25 other tissues See more Orthologs all
SLC2A12, Official Symbol SLC2A12provided by HGNC Official Full Name solute carrier family 2 member 12provided by HGNC Primary source HGNC:HGNC:18067 See related Ensembl:ENSG00000146411 MIM:610372; AllianceGenome:HGNC:18067 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT8; GLUT12 Summary SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008] Expression Broad expression in prostate (RPKM 9.5), endometrium (RPKM 4.6) and 18 other tissues See more Orthologs mouse all
SLC2A13, Official Symbol SLC2A13provided by HGNC Official Full Name solute carrier family 2 member 13provided by HGNC Primary source HGNC:HGNC:15956 See related Ensembl:ENSG00000151229 MIM:611036; AllianceGenome:HGNC:15956 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMIT Summary Enables ATPase binding activity; myo-inositol:proton symporter activity; and protease binding activity. Involved in myo-inositol transport and positive regulation of amyloid-beta formation. Is integral component of plasma membrane. Part of cell body; cell periphery; and cell projection. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 11.8), kidney (RPKM 3.4) and 21 other tissues See more Orthologs mouse all
SLC2A13P1, Official Symbol SLC2A13P1provided by HGNC Official Full Name SLC2A13 pseudogene 1provided by HGNC Primary source HGNC:HGNC:48929 See related Ensembl:ENSG00000254954 AllianceGenome:HGNC:48929 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC2A14, Official Symbol SLC2A14provided by HGNC Official Full Name solute carrier family 2 member 14provided by HGNC Primary source HGNC:HGNC:18301 See related Ensembl:ENSG00000173262 MIM:611039; AllianceGenome:HGNC:18301 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT14; SLC2A3P3 Summary Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression (Wu and Freeze, 2002 [PubMed 12504846]).[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 31.0), bone marrow (RPKM 13.8) and 5 other tissues See more Orthologs all
SLC2A2, Official Symbol SLC2A2provided by HGNC Official Full Name solute carrier family 2 member 2provided by HGNC Primary source HGNC:HGNC:11006 See related Ensembl:ENSG00000163581 MIM:138160; AllianceGenome:HGNC:11006 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT2 Summary This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] Expression Biased expression in liver (RPKM 193.6), duodenum (RPKM 35.6) and 2 other tissues See more Orthologs mouse all
SLC2A3, Official Symbol SLC2A3provided by HGNC Official Full Name solute carrier family 2 member 3provided by HGNC Primary source HGNC:HGNC:11007 See related Ensembl:ENSG00000059804 MIM:138170; AllianceGenome:HGNC:11007 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT3 Summary Enables dehydroascorbic acid transmembrane transporter activity; glucose binding activity; and glucose transmembrane transporter activity. Involved in glucose import across plasma membrane and transport across blood-brain barrier. Is integral component of plasma membrane. Biomarker of Alzheimer's disease; acanthosis nigricans; diabetes mellitus; and type 2 diabetes mellitus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in bone marrow (RPKM 183.0), placenta (RPKM 54.5) and 11 other tissues See more Orthologs mouse all
SLC2A4, Official Symbol SLC2A4provided by HGNC Official Full Name solute carrier family 2 member 4provided by HGNC Primary source HGNC:HGNC:11009 See related Ensembl:ENSG00000181856 MIM:138190; AllianceGenome:HGNC:11009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT4 Summary This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 32.2), fat (RPKM 24.5) and 6 other tissues See more Orthologs mouse all
SLC2A4RG, Official Symbol SLC2A4RGprovided by HGNC Official Full Name SLC2A4 regulatorprovided by HGNC Primary source HGNC:HGNC:15930 See related Ensembl:ENSG00000125520 MIM:609493; AllianceGenome:HGNC:15930 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GEF; HDBP1; HDBP-1; Si-1-2; Si-1-2-19 Summary The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 45.9), kidney (RPKM 36.7) and 25 other tissues See more Orthologs all
SLC2A5, Official Symbol SLC2A5provided by HGNC Official Full Name solute carrier family 2 member 5provided by HGNC Primary source HGNC:HGNC:11010 See related Ensembl:ENSG00000142583 MIM:138230; AllianceGenome:HGNC:11010 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT5; GLUT-5 Summary The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016] Expression Biased expression in duodenum (RPKM 33.7), small intestine (RPKM 25.5) and 8 other tissues See more Orthologs mouse all
SLC2A6, Official Symbol SLC2A6provided by HGNC Official Full Name solute carrier family 2 member 6provided by HGNC Primary source HGNC:HGNC:11011 See related Ensembl:ENSG00000160326 MIM:606813; AllianceGenome:HGNC:11011 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT6; GLUT9; HSA011372 Summary Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.[supplied by OMIM, Jul 2002] Expression Broad expression in spleen (RPKM 3.2), appendix (RPKM 3.1) and 22 other tissues See more Orthologs mouse all
SLC2A7, Official Symbol SLC2A7provided by HGNC Official Full Name solute carrier family 2 member 7provided by HGNC Primary source HGNC:HGNC:13445 See related Ensembl:ENSG00000197241 MIM:610371; AllianceGenome:HGNC:13445 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT7; GLUT-7; hGLUT7 Summary SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Li et al., 2004). This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all