psui3905/ncbi_genes_summary huggingface dataset:
SLC12A2, Official Symbol SLC12A2provided by HGNC Official Full Name solute carrier family 12 member 2provided by HGNC Primary source HGNC:HGNC:10911 See related Ensembl:ENSG00000064651 MIM:600840; AllianceGenome:HGNC:10911 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BSC; BSC2; CCC1; BSC-2; KILQS; NKCC1; PPP1R141 Summary The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Expression Broad expression in colon (RPKM 25.6), stomach (RPKM 18.8) and 22 other tissues See more Orthologs mouse all
SLC12A3, Official Symbol SLC12A3provided by HGNC Official Full Name solute carrier family 12 member 3provided by HGNC Primary source HGNC:HGNC:10912 See related Ensembl:ENSG00000070915 MIM:600968; AllianceGenome:HGNC:10912 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCC; TSC; NCCT Summary This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Restricted expression toward kidney (RPKM 65.2) See more Orthologs mouse all
SLC12A4, Official Symbol SLC12A4provided by HGNC Official Full Name solute carrier family 12 member 4provided by HGNC Primary source HGNC:HGNC:10913 See related Ensembl:ENSG00000124067 MIM:604119; AllianceGenome:HGNC:10913 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCC1; hKCC1; CTC-479C5.17 Summary This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in lung (RPKM 18.3), placenta (RPKM 18.1) and 25 other tissues See more Orthologs mouse all
SLC12A5, Official Symbol SLC12A5provided by HGNC Official Full Name solute carrier family 12 member 5provided by HGNC Primary source HGNC:HGNC:13818 See related Ensembl:ENSG00000124140 MIM:606726; AllianceGenome:HGNC:13818 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCC2; DEE34; EIG14; hKCC2; EIEE34 Summary K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008] Expression Restricted expression toward brain (RPKM 26.0) See more Orthologs mouse all
SLC12A5-AS1, Official Symbol SLC12A5-AS1provided by HGNC Official Full Name SLC12A5 and MMP9 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53143 See related Ensembl:ENSG00000204044 AllianceGenome:HGNC:53143 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC12A6, Official Symbol SLC12A6provided by HGNC Official Full Name solute carrier family 12 member 6provided by HGNC Primary source HGNC:HGNC:10914 See related Ensembl:ENSG00000140199 MIM:604878; AllianceGenome:HGNC:10914 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCC3; ACCPN; KCC3A; KCC3B; CMT2II Summary This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 15.1), bone marrow (RPKM 10.0) and 24 other tissues See more Orthologs mouse all
SLC12A7, Official Symbol SLC12A7provided by HGNC Official Full Name solute carrier family 12 member 7provided by HGNC Primary source HGNC:HGNC:10915 See related Ensembl:ENSG00000113504 MIM:604879; AllianceGenome:HGNC:10915 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCC4 Summary Enables protein kinase binding activity. Predicted to be involved in several processes, including cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 14.3), kidney (RPKM 13.8) and 25 other tissues See more Orthologs mouse all
SLC12A8, Official Symbol SLC12A8provided by HGNC Official Full Name solute carrier family 12 member 8provided by HGNC Primary source HGNC:HGNC:15595 See related Ensembl:ENSG00000221955 MIM:611316; AllianceGenome:HGNC:15595 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCC9 Summary This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010] Expression Broad expression in thyroid (RPKM 11.6), gall bladder (RPKM 6.0) and 17 other tissues See more Orthologs mouse all
SLC12A9, Official Symbol SLC12A9provided by HGNC Official Full Name solute carrier family 12 member 9provided by HGNC Primary source HGNC:HGNC:17435 See related Ensembl:ENSG00000146828 MIM:616861; AllianceGenome:HGNC:17435 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCC6; CIP1; WO3.3; hCCC6 Summary Predicted to enable potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 13.3), spleen (RPKM 11.5) and 25 other tissues See more Orthologs mouse all
SLC12A9-AS1, Official Symbol SLC12A9-AS1provided by HGNC Official Full Name SLC12A9 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40807 See related Ensembl:ENSG00000236305 AllianceGenome:HGNC:40807 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
SLC13A1, Official Symbol SLC13A1provided by HGNC Official Full Name solute carrier family 13 member 1provided by HGNC Primary source HGNC:HGNC:10916 See related Ensembl:ENSG00000081800 MIM:606193; AllianceGenome:HGNC:10916 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAS1; NaSi-1 Summary The protein encoded by this gene is an apical membrane Na(+)-sulfate cotransporter involved in sulfate homeostasis in the kidney. Defects in this gene lead to many pathophysiologic problems. [provided by RefSeq, May 2016] Expression Biased expression in kidney (RPKM 26.2), small intestine (RPKM 5.7) and 1 other tissue See more Orthologs mouse all
SLC13A2, Official Symbol SLC13A2provided by HGNC Official Full Name solute carrier family 13 member 2provided by HGNC Primary source HGNC:HGNC:10917 See related Ensembl:ENSG00000007216 MIM:604148; AllianceGenome:HGNC:10917 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NaCT; NADC1; SDCT1; NaDC-1 Summary The protein encoded by this gene is a sodium-coupled citrate transporter that is regulated by the chaperone activity of cyclophilin b. The encoded protein may play a role in the formation of kidney stones. [provided by RefSeq, Oct 2016] Expression Biased expression in duodenum (RPKM 49.7), small intestine (RPKM 41.0) and 4 other tissues See more Orthologs mouse all
SLC13A3, Official Symbol SLC13A3provided by HGNC Official Full Name solute carrier family 13 member 3provided by HGNC Primary source HGNC:HGNC:14430 See related Ensembl:ENSG00000158296 MIM:606411; AllianceGenome:HGNC:14430 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NaC3; NADC3; SDCT2; ARLIAK Summary Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 195.8) and placenta (RPKM 14.9) See more Orthologs mouse all
SLC13A4, Official Symbol SLC13A4provided by HGNC Official Full Name solute carrier family 13 member 4provided by HGNC Primary source HGNC:HGNC:15827 See related Ensembl:ENSG00000164707 MIM:604309; AllianceGenome:HGNC:15827 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAS2; SUT1; SUT-1 Summary Predicted to enable sodium:sulfate symporter activity. Predicted to be involved in anion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in placenta (RPKM 28.4) and testis (RPKM 3.0) See more Orthologs mouse all
SLC13A5, Official Symbol SLC13A5provided by HGNC Official Full Name solute carrier family 13 member 5provided by HGNC Primary source HGNC:HGNC:23089 See related Ensembl:ENSG00000141485 MIM:608305; AllianceGenome:HGNC:23089 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INDY; NACT; DEE25; mIndy; EIEE25 Summary This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] Expression Biased expression in liver (RPKM 61.1) and salivary gland (RPKM 7.3) See more Orthologs mouse all
SLC14A1, Official Symbol SLC14A1provided by HGNC Official Full Name solute carrier family 14 member 1 (Kidd blood group)provided by HGNC Primary source HGNC:HGNC:10918 See related Ensembl:ENSG00000141469 MIM:613868; AllianceGenome:HGNC:10918 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JK; UT1; UTE; HUT11; Jk(a); Jk(b); RACH1; RACH2; UT-B1; HUT11A; HsT1341 Summary The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009] Expression Biased expression in prostate (RPKM 18.0), urinary bladder (RPKM 11.5) and 8 other tissues See more Orthologs mouse all
SLC14A2, Official Symbol SLC14A2provided by HGNC Official Full Name solute carrier family 14 member 2provided by HGNC Primary source HGNC:HGNC:10919 See related Ensembl:ENSG00000132874 MIM:601611; AllianceGenome:HGNC:10919 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UT2; UTA; UTR; HUT2; UT-A2; hUT-A6 Summary The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011] Expression Biased expression in kidney (RPKM 2.6), fat (RPKM 1.3) and 7 other tissues See more Orthologs mouse all
SLC15A1, Official Symbol SLC15A1provided by HGNC Official Full Name solute carrier family 15 member 1provided by HGNC Primary source HGNC:HGNC:10920 See related Ensembl:ENSG00000088386 MIM:600544; AllianceGenome:HGNC:10920 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEPT1; HPECT1; HPEPT1 Summary This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010] Expression Biased expression in small intestine (RPKM 105.5), duodenum (RPKM 76.1) and 2 other tissues See more Orthologs mouse all
SLC15A2, Official Symbol SLC15A2provided by HGNC Official Full Name solute carrier family 15 member 2provided by HGNC Primary source HGNC:HGNC:10921 See related Ensembl:ENSG00000163406 MIM:602339; AllianceGenome:HGNC:10921 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEPT2 Summary The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).[supplied by OMIM, Feb 2011] Expression Biased expression in prostate (RPKM 19.8), brain (RPKM 10.1) and 13 other tissues See more Orthologs mouse all
SLC15A3, Official Symbol SLC15A3provided by HGNC Official Full Name solute carrier family 15 member 3provided by HGNC Primary source HGNC:HGNC:18068 See related Ensembl:ENSG00000110446 MIM:610408; AllianceGenome:HGNC:18068 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OCTP; PHT2; PTR3 Summary Enables dipeptide transmembrane transporter activity. Involved in dipeptide import across plasma membrane. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 20.2), lung (RPKM 17.9) and 23 other tissues See more Orthologs mouse all
SLC15A4, Official Symbol SLC15A4provided by HGNC Official Full Name solute carrier family 15 member 4provided by HGNC Primary source HGNC:HGNC:23090 See related Ensembl:ENSG00000139370 MIM:615806; AllianceGenome:HGNC:23090 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHT1; PTR4; FP12591 Summary Enables L-histidine transmembrane transporter activity; peptide transmembrane transporter activity; and peptidoglycan transmembrane transporter activity. Involved in several processes, including dipeptide import across plasma membrane; peptidoglycan transport; and positive regulation of toll-like receptor signaling pathway. Located in endolysosome membrane. Is integral component of lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 17.6), testis (RPKM 10.0) and 25 other tissues See more Orthologs mouse all
SLC15A5, Official Symbol SLC15A5provided by HGNC Official Full Name solute carrier family 15 member 5provided by HGNC Primary source HGNC:HGNC:33455 See related Ensembl:ENSG00000188991 MIM:620324; AllianceGenome:HGNC:33455 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable symporter activity. Predicted to be involved in peptide transport; protein transport; and transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
SLC16A1, Official Symbol SLC16A1provided by HGNC Official Full Name solute carrier family 16 member 1provided by HGNC Primary source HGNC:HGNC:10922 See related Ensembl:ENSG00000155380 MIM:600682; AllianceGenome:HGNC:10922 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT; HHF7; MCT1; MCT1D Summary The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009] Expression Broad expression in heart (RPKM 23.3), colon (RPKM 22.1) and 23 other tissues See more Orthologs mouse all
SLC16A1-AS1, Official Symbol SLC16A1-AS1provided by HGNC Official Full Name SLC16A1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:49445 See related Ensembl:ENSG00000226419 AllianceGenome:HGNC:49445 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 1.4), colon (RPKM 1.2) and 23 other tissues See more
SLC16A10, Official Symbol SLC16A10provided by HGNC Official Full Name solute carrier family 16 member 10provided by HGNC Primary source HGNC:HGNC:17027 See related Ensembl:ENSG00000112394 MIM:607550; AllianceGenome:HGNC:17027 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TAT1; MCT10; PRO0813 Summary SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004] Expression Broad expression in placenta (RPKM 4.2), skin (RPKM 2.5) and 19 other tissues See more Orthologs mouse all
SLC16A11, Official Symbol SLC16A11provided by HGNC Official Full Name solute carrier family 16 member 11provided by HGNC Primary source HGNC:HGNC:23093 See related Ensembl:ENSG00000174326 MIM:615765; AllianceGenome:HGNC:23093 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT11; MCT 11 Summary Enables pyruvate transmembrane transporter activity. Involved in lipid metabolic process. Located in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 1.1), lung (RPKM 1.1) and 22 other tissues See more Orthologs mouse all
SLC16A12, Official Symbol SLC16A12provided by HGNC Official Full Name solute carrier family 16 member 12provided by HGNC Primary source HGNC:HGNC:23094 See related Ensembl:ENSG00000152779 MIM:611910; AllianceGenome:HGNC:23094 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CJMG; CRT2; MCT12; CTRCT47 Summary This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010] Expression Biased expression in kidney (RPKM 36.5), placenta (RPKM 6.6) and 1 other tissue See more Orthologs mouse all
SLC16A12-AS1, Official Symbol SLC16A12-AS1provided by HGNC Official Full Name SLC16A12 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:51205 See related Ensembl:ENSG00000234452 AllianceGenome:HGNC:51205 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 10.6), placenta (RPKM 2.1) and 2 other tissues See more
SLC16A13, Official Symbol SLC16A13provided by HGNC Official Full Name solute carrier family 16 member 13provided by HGNC Primary source HGNC:HGNC:31037 See related Ensembl:ENSG00000174327 AllianceGenome:HGNC:31037 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT13 Summary Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in liver (RPKM 11.1), kidney (RPKM 6.1) and 17 other tissues See more Orthologs mouse all
SLC16A14, Official Symbol SLC16A14provided by HGNC Official Full Name solute carrier family 16 member 14provided by HGNC Primary source HGNC:HGNC:26417 See related Ensembl:ENSG00000163053 AllianceGenome:HGNC:26417 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT14 Summary Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 4.6), brain (RPKM 4.6) and 24 other tissues See more Orthologs mouse all
SLC16A14P1, Official Symbol SLC16A14P1provided by HGNC Official Full Name solute carrier family 16 member 14 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43809 See related Ensembl:ENSG00000213708 AllianceGenome:HGNC:43809 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC16A2, Official Symbol SLC16A2provided by HGNC Official Full Name solute carrier family 16 member 2provided by HGNC Primary source HGNC:HGNC:10923 See related Ensembl:ENSG00000147100 MIM:300095; AllianceGenome:HGNC:10923 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AHDS; MCT7; MCT8; XPCT; MCT 7; MCT 8; MRX22; DXS128; DXS128E Summary This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012] Expression Broad expression in liver (RPKM 21.4), adrenal (RPKM 17.4) and 22 other tissues See more Orthologs mouse all
SLC16A3, Official Symbol SLC16A3provided by HGNC Official Full Name solute carrier family 16 member 3provided by HGNC Primary source HGNC:HGNC:10924 See related Ensembl:ENSG00000141526 MIM:603877; AllianceGenome:HGNC:10924 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT3; MCT4; MCT 3; MCT 4; MCT-3; MCT-4 Summary Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008] Expression Broad expression in placenta (RPKM 10.2), appendix (RPKM 8.8) and 22 other tissues See more Orthologs mouse all
SLC16A4, Official Symbol SLC16A4provided by HGNC Official Full Name solute carrier family 16 member 4provided by HGNC Primary source HGNC:HGNC:10925 See related Ensembl:ENSG00000168679 MIM:603878; AllianceGenome:HGNC:10925 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT4; MCT5 Summary Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 44.3), placenta (RPKM 12.3) and 10 other tissues See more Orthologs mouse all
SLC16A5, Official Symbol SLC16A5provided by HGNC Official Full Name solute carrier family 16 member 5provided by HGNC Primary source HGNC:HGNC:10926 See related Ensembl:ENSG00000170190 MIM:603879; AllianceGenome:HGNC:10926 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT5; MCT6 Summary This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] Expression Broad expression in lung (RPKM 9.8), duodenum (RPKM 9.3) and 21 other tissues See more Orthologs mouse all
SLC16A6, Official Symbol SLC16A6provided by HGNC Official Full Name solute carrier family 16 member 6provided by HGNC Primary source HGNC:HGNC:10927 See related Ensembl:ENSG00000108932 MIM:603880; AllianceGenome:HGNC:10927 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT6; MCT7 Summary Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 4.8), appendix (RPKM 3.2) and 18 other tissues See more Orthologs mouse all
SLC16A7, Official Symbol SLC16A7provided by HGNC Official Full Name solute carrier family 16 member 7provided by HGNC Primary source HGNC:HGNC:10928 See related Ensembl:ENSG00000118596 MIM:603654; AllianceGenome:HGNC:10928 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT2 Summary This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] Expression Broad expression in fat (RPKM 11.7), heart (RPKM 9.2) and 22 other tissues See more Orthologs mouse all
SLC16A8, Official Symbol SLC16A8provided by HGNC Official Full Name solute carrier family 16 member 8provided by HGNC Primary source HGNC:HGNC:16270 See related Ensembl:ENSG00000100156 MIM:610409; AllianceGenome:HGNC:16270 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT3; REMP Summary SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010] Expression Broad expression in prostate (RPKM 2.1), testis (RPKM 0.9) and 20 other tissues See more Orthologs mouse all
SLC16A9, Official Symbol SLC16A9provided by HGNC Official Full Name solute carrier family 16 member 9provided by HGNC Primary source HGNC:HGNC:23520 See related Ensembl:ENSG00000165449 MIM:614242; AllianceGenome:HGNC:23520 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT9; C10orf36 Summary Predicted to enable monocarboxylic acid transmembrane transporter activity. Involved in urate metabolic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in adrenal (RPKM 82.1), kidney (RPKM 62.2) and 9 other tissues See more Orthologs mouse all
SLC17A1, Official Symbol SLC17A1provided by HGNC Official Full Name solute carrier family 17 member 1provided by HGNC Primary source HGNC:HGNC:10929 See related Ensembl:ENSG00000124568 MIM:182308; AllianceGenome:HGNC:10929 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPT1; NPT-1; NAPI-1 Summary Predicted to enable sialic acid transmembrane transporter activity. Involved in urate metabolic process and urate transport. Located in apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward kidney (RPKM 52.9) See more Orthologs mouse all
SLC17A2, Official Symbol SLC17A2provided by HGNC Official Full Name solute carrier family 17 member 2provided by HGNC Primary source HGNC:HGNC:10930 See related Ensembl:ENSG00000112337 MIM:611049; AllianceGenome:HGNC:10930 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPT3 Summary Predicted to enable sialic acid transmembrane transporter activity. Predicted to be involved in sialic acid transport. Predicted to be located in membrane. Predicted to be active in lysosome. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward liver (RPKM 16.0) See more Orthologs mouse all
SLC17A3, Official Symbol SLC17A3provided by HGNC Official Full Name solute carrier family 17 member 3provided by HGNC Primary source HGNC:HGNC:10931 See related Ensembl:ENSG00000124564 MIM:611034; AllianceGenome:HGNC:10931 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPT4; GOUT4; UAQTL4 Summary The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to the endoplasmic reticulum. [provided by RefSeq, Aug 2012] Expression Restricted expression toward kidney (RPKM 57.7) See more Orthologs mouse all
SLC17A4, Official Symbol SLC17A4provided by HGNC Official Full Name solute carrier family 17 member 4provided by HGNC Primary source HGNC:HGNC:10932 See related Ensembl:ENSG00000146039 MIM:604216; AllianceGenome:HGNC:10932 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAIA2138 Summary Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011] Expression Biased expression in small intestine (RPKM 10.3), duodenum (RPKM 9.0) and 5 other tissues See more Orthologs mouse all
SLC17A5, Official Symbol SLC17A5provided by HGNC Official Full Name solute carrier family 17 member 5provided by HGNC Primary source HGNC:HGNC:10933 See related Ensembl:ENSG00000119899 MIM:604322; AllianceGenome:HGNC:10933 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SD; AST; NSD; SLD; ISSD; VEAT; SIASD; SIALIN Summary This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 24.0), kidney (RPKM 11.9) and 24 other tissues See more Orthologs mouse all
SLC17A6, Official Symbol SLC17A6provided by HGNC Official Full Name solute carrier family 17 member 6provided by HGNC Primary source HGNC:HGNC:16703 See related Ensembl:ENSG00000091664 MIM:607563; AllianceGenome:HGNC:16703 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DNPI; VGLUT2 Summary Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in neurotransmitter loading into synaptic vesicle. Predicted to be located in synaptic vesicle. Predicted to be active in excitatory synapse. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 2.7) See more Orthologs mouse all
SLC17A7, Official Symbol SLC17A7provided by HGNC Official Full Name solute carrier family 17 member 7provided by HGNC Primary source HGNC:HGNC:16704 See related Ensembl:ENSG00000104888 MIM:605208; AllianceGenome:HGNC:16704 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BNPI; VGLUT1 Summary The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008] Expression Restricted expression toward brain (RPKM 231.7) See more Orthologs mouse all
SLC17A8, Official Symbol SLC17A8provided by HGNC Official Full Name solute carrier family 17 member 8provided by HGNC Primary source HGNC:HGNC:20151 See related Ensembl:ENSG00000179520 MIM:607557; AllianceGenome:HGNC:20151 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNA25; VGLUT3 Summary This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Expression Biased expression in small intestine (RPKM 3.2), brain (RPKM 0.5) and 3 other tissues See more Orthologs mouse all
SLC17A9, Official Symbol SLC17A9provided by HGNC Official Full Name solute carrier family 17 member 9provided by HGNC Primary source HGNC:HGNC:16192 See related Ensembl:ENSG00000101194 MIM:612107; AllianceGenome:HGNC:16192 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VNUT; POROK8; C20orf59 Summary This gene encodes a member of a family of transmembrane proteins that are involved in the transport of small molecules. The encoded protein participates in the vesicular uptake, storage, and secretion of adenoside triphosphate (ATP) and other nucleotides. A mutation in this gene was found in individuals with autosomal dominant disseminated superficial actinic porokeratosis-8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Broad expression in stomach (RPKM 12.3), bone marrow (RPKM 8.3) and 20 other tissues See more Orthologs mouse all
SLC18A1, Official Symbol SLC18A1provided by HGNC Official Full Name solute carrier family 18 member A1provided by HGNC Primary source HGNC:HGNC:10934 See related Ensembl:ENSG00000036565 MIM:193002; AllianceGenome:HGNC:10934 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGAT; VAT1; VMAT1 Summary The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008] Expression Biased expression in adrenal (RPKM 13.1), colon (RPKM 1.0) and 1 other tissue See more Orthologs mouse all
SLC18A2, Official Symbol SLC18A2provided by HGNC Official Full Name solute carrier family 18 member A2provided by HGNC Primary source HGNC:HGNC:10935 See related Ensembl:ENSG00000165646 MIM:193001; AllianceGenome:HGNC:10935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SVAT; SVMT; VAT2; VMAT2; PKDYS2 Summary This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018] Expression Ubiquitous expression in adrenal (RPKM 12.2), ovary (RPKM 7.2) and 25 other tissues See more Orthologs mouse all
SLC18A3, Official Symbol SLC18A3provided by HGNC Official Full Name solute carrier family 18 member A3provided by HGNC Primary source HGNC:HGNC:10936 See related Ensembl:ENSG00000187714 MIM:600336; AllianceGenome:HGNC:10936 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMS21; VACHT Summary This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008] Orthologs mouse all
SLC18B1, Official Symbol SLC18B1provided by HGNC Official Full Name solute carrier family 18 member B1provided by HGNC Primary source HGNC:HGNC:21573 See related Ensembl:ENSG00000146409 MIM:613361; AllianceGenome:HGNC:21573 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VPAT; C6orf192; dJ55C23.6 Summary This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 13.1), duodenum (RPKM 8.9) and 25 other tissues See more Orthologs mouse all