psui3905/ncbi_genes_summary huggingface dataset:
HNRNPF, Official Symbol HNRNPFprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Fprovided by HGNC Primary source HGNC:HGNC:5039 See related Ensembl:ENSG00000169813 MIM:601037; AllianceGenome:HGNC:5039 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPF; mcs94-1; OK/SW-cl.23 Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 61.3), appendix (RPKM 55.5) and 25 other tissues See more Orthologs mouse all
HNRNPH1, Official Symbol HNRNPH1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H1provided by HGNC Primary source HGNC:HGNC:5041 See related Ensembl:ENSG00000169045 MIM:601035; AllianceGenome:HGNC:5041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPH; HNRPH1; NEDCDS; hnRNPH Summary This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in bone marrow (RPKM 153.8), lymph node (RPKM 101.7) and 25 other tissues See more Orthologs mouse all
HNRNPH1P1, Official Symbol HNRNPH1P1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:48751 See related Ensembl:ENSG00000220305 AllianceGenome:HGNC:48751 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPH1P2, Official Symbol HNRNPH1P2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:48810 See related Ensembl:ENSG00000213924 AllianceGenome:HGNC:48810 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPH2, Official Symbol HNRNPH2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H2provided by HGNC Primary source HGNC:HGNC:5042 See related Ensembl:ENSG00000126945 MIM:300610; AllianceGenome:HGNC:5042 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FTP3; MRXSB; NRPH2; HNRPH'; HNRPH2; hnRNPH' Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in brain (RPKM 50.7), adrenal (RPKM 42.7) and 25 other tissues See more Orthologs mouse all
HNRNPH3, Official Symbol HNRNPH3provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H3provided by HGNC Primary source HGNC:HGNC:5043 See related Ensembl:ENSG00000096746 MIM:602324; AllianceGenome:HGNC:5043 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2H9; HNRPH3 Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 44.3), ovary (RPKM 43.6) and 25 other tissues See more Orthologs mouse all
HNRNPH3P1, Official Symbol HNRNPH3P1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H3 pseudogene 1provided by HGNC Primary source HGNC:HGNC:48750 See related Ensembl:ENSG00000230247 AllianceGenome:HGNC:48750 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPK, Official Symbol HNRNPKprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Kprovided by HGNC Primary source HGNC:HGNC:5044 See related Ensembl:ENSG00000165119 MIM:600712; AllianceGenome:HGNC:5044 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AUKS; CSBP; TUNP; HNRPK Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 179.3), lymph node (RPKM 145.8) and 25 other tissues See more Orthologs mouse all
HNRNPKP1, Official Symbol HNRNPKP1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein K pseudogene 1provided by HGNC Primary source HGNC:HGNC:42374 See related Ensembl:ENSG00000250859 AllianceGenome:HGNC:42374 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPKP2, Official Symbol HNRNPKP2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein K pseudogene 2provided by HGNC Primary source HGNC:HGNC:42375 See related Ensembl:ENSG00000227347 AllianceGenome:HGNC:42375 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPKP3, Official Symbol HNRNPKP3provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein K pseudogene 3provided by HGNC Primary source HGNC:HGNC:42376 See related Ensembl:ENSG00000251557 AllianceGenome:HGNC:42376 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
HNRNPKP4, Official Symbol HNRNPKP4provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein K pseudogene 4provided by HGNC Primary source HGNC:HGNC:42377 See related Ensembl:ENSG00000243547 AllianceGenome:HGNC:42377 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPL, Official Symbol HNRNPLprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Lprovided by HGNC Primary source HGNC:HGNC:5045 See related Ensembl:ENSG00000104824 MIM:603083; AllianceGenome:HGNC:5045 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPL; hnRNP-L; P/OKcl.14 Summary Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 99.2), lymph node (RPKM 60.1) and 25 other tissues See more Orthologs mouse all
HNRNPLL, Official Symbol HNRNPLLprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein L likeprovided by HGNC Primary source HGNC:HGNC:25127 See related Ensembl:ENSG00000143889 MIM:611208; AllianceGenome:HGNC:25127 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRRF; HNRPLL Summary HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008] Expression Ubiquitous expression in testis (RPKM 17.8), thyroid (RPKM 11.5) and 25 other tissues See more Orthologs mouse all
HNRNPLP1, Official Symbol HNRNPLP1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein L pseudogene 1provided by HGNC Primary source HGNC:HGNC:48748 See related Ensembl:ENSG00000233503 AllianceGenome:HGNC:48748 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPLP2, Official Symbol HNRNPLP2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein L pseudogene 2provided by HGNC Primary source HGNC:HGNC:48747 See related AllianceGenome:HGNC:48747 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPM, Official Symbol HNRNPMprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Mprovided by HGNC Primary source HGNC:HGNC:5046 See related Ensembl:ENSG00000099783 MIM:160994; AllianceGenome:HGNC:5046 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEAR; HNRPM; HTGR1; NAGR1; HNRPM4; HNRNPM4; hnRNP M Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in bone marrow (RPKM 50.0), colon (RPKM 44.6) and 25 other tissues See more Orthologs mouse all
HNRNPMP1, Official Symbol HNRNPMP1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein M pseudogene 1provided by HGNC Primary source HGNC:HGNC:48745 See related Ensembl:ENSG00000259335 AllianceGenome:HGNC:48745 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPMP2, Official Symbol HNRNPMP2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein M pseudogene 2provided by HGNC Primary source HGNC:HGNC:48746 See related Ensembl:ENSG00000275862 AllianceGenome:HGNC:48746 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPR, Official Symbol HNRNPRprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Rprovided by HGNC Primary source HGNC:HGNC:5047 See related Ensembl:ENSG00000125944 MIM:607201; AllianceGenome:HGNC:5047 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPR; NEDDFSB; hnRNP-R Summary This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in lymph node (RPKM 17.7), appendix (RPKM 17.6) and 25 other tissues See more Orthologs mouse all
HNRNPRP2, Official Symbol HNRNPRP2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein R pseudogene 2provided by HGNC Primary source HGNC:HGNC:44908 See related Ensembl:ENSG00000255047 AllianceGenome:HGNC:44908 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HNRNPU, Official Symbol HNRNPUprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein Uprovided by HGNC Primary source HGNC:HGNC:5048 See related Ensembl:ENSG00000153187 MIM:602869; AllianceGenome:HGNC:5048 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAFA; DEE54; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1 Summary This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017] Expression Ubiquitous expression in bone marrow (RPKM 31.0), lymph node (RPKM 28.0) and 25 other tissues See more Orthologs mouse all
HNRNPUL1, Official Symbol HNRNPUL1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein U like 1provided by HGNC Primary source HGNC:HGNC:17011 See related Ensembl:ENSG00000105323 MIM:605800; AllianceGenome:HGNC:17011 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E1BAP5; E1B-AP5; HNRPUL1 Summary This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in testis (RPKM 41.5), ovary (RPKM 40.7) and 25 other tissues See more Orthologs mouse all
HNRNPUL2, Official Symbol HNRNPUL2provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein U like 2provided by HGNC Primary source HGNC:HGNC:25451 See related Ensembl:ENSG00000214753 AllianceGenome:HGNC:25451 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAF-A2; HNRPUL2 Summary Enables RNA binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 35.1), colon (RPKM 29.9) and 25 other tissues See more Orthologs mouse all
HNRNPUL2-BSCL2, Official Symbol HNRNPUL2-BSCL2provided by HGNC Official Full Name HNRNPUL2-BSCL2 readthrough (NMD candidate)provided by HGNC Primary source HGNC:HGNC:49189 See related Ensembl:ENSG00000234857 AllianceGenome:HGNC:49189 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring read-through transcription between the neighboring HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2) and BSCL2 (Berardinelli-Seip congenital lipodystrophy 2 (seipin)) genes on chromosome 11. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Mar 2011] Expression Ubiquitous expression in brain (RPKM 70.8), testis (RPKM 60.4) and 25 other tissues See more
HNRNPUP1, Official Symbol HNRNPUP1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein U pseudogene 1provided by HGNC Primary source HGNC:HGNC:19931 See related AllianceGenome:HGNC:19931 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPUP
HOATZ, Official Symbol HOATZprovided by HGNC Official Full Name HOATZ cilia and flagella associated proteinprovided by HGNC Primary source HGNC:HGNC:25061 See related Ensembl:ENSG00000183644 AllianceGenome:HGNC:25061 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C11orf88 Summary Predicted to be involved in axoneme assembly; flagellated sperm motility; and spermatogenesis. Predicted to be located in cilium and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 9.4), lung (RPKM 6.2) and 1 other tissue See more Orthologs mouse all
HOGA1, Official Symbol HOGA1provided by HGNC Official Full Name 4-hydroxy-2-oxoglutarate aldolase 1provided by HGNC Primary source HGNC:HGNC:25155 See related Ensembl:ENSG00000241935 MIM:613597; AllianceGenome:HGNC:25155 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HP3; NPL2; DHDPS2; DHDPSL; C10orf65 Summary The authors of PMID:20797690 cloned this gene while searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Nov 2010] Expression Biased expression in kidney (RPKM 27.4), liver (RPKM 9.9) and 5 other tissues See more Orthologs mouse all
HOMER1, Official Symbol HOMER1provided by HGNC Official Full Name homer scaffold protein 1provided by HGNC Primary source HGNC:HGNC:17512 See related Ensembl:ENSG00000152413 MIM:604798; AllianceGenome:HGNC:17512 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER1C Summary This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 8.6), thyroid (RPKM 5.8) and 14 other tissues See more Orthologs mouse all
HOMER2, Official Symbol HOMER2provided by HGNC Official Full Name homer scaffold protein 2provided by HGNC Primary source HGNC:HGNC:17513 See related Ensembl:ENSG00000103942 MIM:604799; AllianceGenome:HGNC:17513 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPD; ACPD; DFNA68; VESL-2; HOMER-2 Summary This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011] Expression Broad expression in prostate (RPKM 9.3), pancreas (RPKM 6.8) and 16 other tissues See more Orthologs mouse all
HOMER3, Official Symbol HOMER3provided by HGNC Official Full Name homer scaffold protein 3provided by HGNC Primary source HGNC:HGNC:17514 See related Ensembl:ENSG00000051128 MIM:604800; AllianceGenome:HGNC:17514 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VESL3; HOMER-3 Summary This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] Expression Broad expression in spleen (RPKM 29.6), kidney (RPKM 6.7) and 19 other tissues See more Orthologs mouse all
HOMER3-AS1, Official Symbol HOMER3-AS1provided by HGNC Official Full Name HOMER3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53775 See related AllianceGenome:HGNC:53775 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in spleen (RPKM 3.4), kidney (RPKM 0.6) and 18 other tissues See more
HOMEZ, Official Symbol HOMEZprovided by HGNC Official Full Name homeobox and leucine zipper encodingprovided by HGNC Primary source HGNC:HGNC:20164 See related Ensembl:ENSG00000290292 MIM:608119; AllianceGenome:HGNC:20164 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA1443 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 9.5), urinary bladder (RPKM 4.3) and 24 other tissues See more Orthologs mouse all
HOOK1, Official Symbol HOOK1provided by HGNC Official Full Name hook microtubule tethering protein 1provided by HGNC Primary source HGNC:HGNC:19884 See related Ensembl:ENSG00000134709 MIM:607820; AllianceGenome:HGNC:19884 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HK1 Summary This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 15.7), colon (RPKM 10.0) and 21 other tissues See more Orthologs mouse all
HOOK2, Official Symbol HOOK2provided by HGNC Official Full Name hook microtubule tethering protein 2provided by HGNC Primary source HGNC:HGNC:19885 See related Ensembl:ENSG00000095066 MIM:607824; AllianceGenome:HGNC:19885 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HK2 Summary Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in fat (RPKM 18.1), duodenum (RPKM 14.2) and 24 other tissues See more Orthologs mouse all
HOOK3, Official Symbol HOOK3provided by HGNC Official Full Name hook microtubule tethering protein 3provided by HGNC Primary source HGNC:HGNC:23576 See related Ensembl:ENSG00000168172 MIM:607825; AllianceGenome:HGNC:23576 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HK3 Summary Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in thyroid (RPKM 6.6), fat (RPKM 4.5) and 25 other tissues See more Orthologs mouse all
HOPX, Official Symbol HOPXprovided by HGNC Official Full Name HOP homeoboxprovided by HGNC Primary source HGNC:HGNC:24961 See related Ensembl:ENSG00000171476 MIM:607275; AllianceGenome:HGNC:24961 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOD; HOP; OB1; LAGY; TOTO; CAMEO; NECC1; SMAP31 Summary The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009] Expression Biased expression in skin (RPKM 80.6), esophagus (RPKM 62.3) and 8 other tissues See more Orthologs mouse all
HORMAD1, Official Symbol HORMAD1provided by HGNC Official Full Name HORMA domain containing 1provided by HGNC Primary source HGNC:HGNC:25245 See related Ensembl:ENSG00000143452 MIM:609824; AllianceGenome:HGNC:25245 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT46; NOHMA Summary This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Expression Restricted expression toward testis (RPKM 50.3) See more Orthologs mouse all
HORMAD2, Official Symbol HORMAD2provided by HGNC Official Full Name HORMA domain containing 2provided by HGNC Primary source HGNC:HGNC:28383 See related Ensembl:ENSG00000176635 MIM:618842; AllianceGenome:HGNC:28383 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT46.2 Summary Predicted to be involved in meiotic sister chromatid cohesion. Located in centrosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 6.8) See more Orthologs mouse all
HORMAD2-AS1, Official Symbol HORMAD2-AS1provided by HGNC Official Full Name HORMAD2 and MTMR3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:50729 See related Ensembl:ENSG00000227117 AllianceGenome:HGNC:50729 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MTMR3-AS1 Expression Ubiquitous expression in liver (RPKM 3.9), testis (RPKM 3.7) and 25 other tissues See more
HOTAIR, Official Symbol HOTAIRprovided by HGNC Official Full Name HOX transcript antisense RNAprovided by HGNC Primary source HGNC:HGNC:33510 See related Ensembl:ENSG00000228630 MIM:611400; AllianceGenome:HGNC:33510 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072 Summary This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019] Expression Biased expression in testis (RPKM 1.6), skin (RPKM 1.2) and 6 other tissues See more Orthologs mouse all
HOTAIRM1, Official Symbol HOTAIRM1provided by HGNC Official Full Name HOXA transcript antisense RNA, myeloid-specific 1provided by HGNC Primary source HGNC:HGNC:37117 See related Ensembl:ENSG00000233429 AllianceGenome:HGNC:37117 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXA-AS1; HOXA1-AS1; NCRNA00179 Summary This non-coding locus is located in the HOX gene cluster. Transcription of this locus is induced by retinoic acid, and transcripts likely function in regulation of myelopoiesis through transcriptional activation of several genes in the HOXA cluster, in addition to several beta-2 integrins. [provided by RefSeq, Jan 2013] Expression Broad expression in adrenal (RPKM 4.5), spleen (RPKM 4.0) and 19 other tissues See more Orthologs mouse all
HOXA-AS2, Official Symbol HOXA-AS2provided by HGNC Official Full Name HOXA cluster antisense RNA 2provided by HGNC Primary source HGNC:HGNC:43745 See related MIM:616068; AllianceGenome:HGNC:43745 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXA3as Summary This gene produces a long non-coding RNA that promotes cell proliferation. This transcript may interact with enhancer of zeste homolog 2 Polycomb repressive complex to repress gene expression. [provided by RefSeq, Dec 2017] Expression Broad expression in kidney (RPKM 3.0), lung (RPKM 2.4) and 18 other tissues See more Orthologs all
HOXA-AS3, Official Symbol HOXA-AS3provided by HGNC Official Full Name HOXA cluster antisense RNA 3provided by HGNC Primary source HGNC:HGNC:43748 See related Ensembl:ENSG00000254369 MIM:618706; AllianceGenome:HGNC:43748 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXA6as Expression Broad expression in kidney (RPKM 3.9), adrenal (RPKM 3.4) and 14 other tissues See more
HOXA1, Official Symbol HOXA1provided by HGNC Official Full Name homeobox A1provided by HGNC Primary source HGNC:HGNC:5099 See related Ensembl:ENSG00000105991 MIM:142955; AllianceGenome:HGNC:5099 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BSAS; HOX1; HOX1F Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008] Expression Biased expression in urinary bladder (RPKM 4.0), skin (RPKM 1.0) and 13 other tissues See more Orthologs mouse all
HOXA10, Official Symbol HOXA10provided by HGNC Official Full Name homeobox A10provided by HGNC Primary source HGNC:HGNC:5100 See related Ensembl:ENSG00000253293 MIM:142957; AllianceGenome:HGNC:5100 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PL; HOX1; HOX1H; HOX1.8 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011] Expression Biased expression in endometrium (RPKM 36.7), prostate (RPKM 13.4) and 7 other tissues See more Orthologs mouse all
HOXA10-AS, Official Symbol HOXA10-ASprovided by HGNC Official Full Name HOXA10 antisense RNAprovided by HGNC Primary source HGNC:HGNC:40281 See related Ensembl:ENSG00000253187 AllianceGenome:HGNC:40281 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXA-AS4 Expression Biased expression in endometrium (RPKM 40.3), prostate (RPKM 15.7) and 8 other tissues See more Orthologs mouse all
HOXA10-HOXA9, Gene symbol HOXA10-HOXA9 Gene description HOXA10-HOXA9 readthrough Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring read-through transcription between the neighboring HOXA10 (homeobox A10) and HOXA9 (full description written out) genes on chromosome 7. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Mar 2011] Expression Biased expression in endometrium (RPKM 11.2), kidney (RPKM 10.8) and 11 other tissues See more
HOXA11, Official Symbol HOXA11provided by HGNC Official Full Name homeobox A11provided by HGNC Primary source HGNC:HGNC:5101 See related Ensembl:ENSG00000005073 MIM:142958; AllianceGenome:HGNC:5101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1I; RUSAT1 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 34.9), prostate (RPKM 6.8) and 4 other tissues See more Orthologs mouse all
HOXA11-AS, Official Symbol HOXA11-ASprovided by HGNC Official Full Name HOXA11 antisense RNAprovided by HGNC Primary source HGNC:HGNC:24957 See related Ensembl:ENSG00000240990 MIM:607530; AllianceGenome:HGNC:24957 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXA11S; HOXA-AS5; HOXA11AS; HOXA11-AS1; NCRNA00076 Summary This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017] Expression Biased expression in prostate (RPKM 18.6), endometrium (RPKM 8.7) and 3 other tissues See more Orthologs mouse all
HOXA13, Official Symbol HOXA13provided by HGNC Official Full Name homeobox A13provided by HGNC Primary source HGNC:HGNC:5102 See related Ensembl:ENSG00000106031 MIM:142959; AllianceGenome:HGNC:5102 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1J Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 14.7), placenta (RPKM 10.9) and 2 other tissues See more Orthologs mouse all
HOXA2, Official Symbol HOXA2provided by HGNC Official Full Name homeobox A2provided by HGNC Primary source HGNC:HGNC:5103 See related Ensembl:ENSG00000105996 MIM:604685; AllianceGenome:HGNC:5103 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1K; MCOHI Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 1.2), fat (RPKM 0.8) and 19 other tissues See more Orthologs mouse all