psui3905/ncbi_genes_summary huggingface dataset:
LURAP1L-AS1, Official Symbol LURAP1L-AS1provided by HGNC Official Full Name LURAP1L antisense RNA 1provided by HGNC Primary source HGNC:HGNC:49761 See related Ensembl:ENSG00000235448 AllianceGenome:HGNC:49761 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
LUZP1, Official Symbol LUZP1provided by HGNC Official Full Name leucine zipper protein 1provided by HGNC Primary source HGNC:HGNC:14985 See related Ensembl:ENSG00000169641 MIM:601422; AllianceGenome:HGNC:14985 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LUZP Summary This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] Expression Ubiquitous expression in small intestine (RPKM 10.5), duodenum (RPKM 8.9) and 25 other tissues See more Orthologs mouse all
LUZP2, Official Symbol LUZP2provided by HGNC Official Full Name leucine zipper protein 2provided by HGNC Primary source HGNC:HGNC:23206 See related Ensembl:ENSG00000187398 MIM:608178; AllianceGenome:HGNC:23206 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO6246; KFSP2566 Summary This gene encodes a leucine zipper protein. This protein is deleted in some patients with Wilms tumor-Aniridia-Genitourinary anomalies-mental Retardation (WAGR) syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011] Expression Biased expression in brain (RPKM 5.0), adrenal (RPKM 1.6) and 1 other tissue See more Orthologs mouse all
LUZP4, Official Symbol LUZP4provided by HGNC Official Full Name leucine zipper protein 4provided by HGNC Primary source HGNC:HGNC:24971 See related Ensembl:ENSG00000102021 MIM:300616; AllianceGenome:HGNC:24971 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT-8; CT28; CT-28; HOM-TES-85 Summary This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Restricted expression toward testis (RPKM 5.6) See more Orthologs all
LVRN, Official Symbol LVRNprovided by HGNC Official Full Name laeverinprovided by HGNC Primary source HGNC:HGNC:26904 See related Ensembl:ENSG00000172901 MIM:610046; AllianceGenome:HGNC:26904 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APQ; AQPEP; TAQPEP Summary Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in fat (RPKM 11.6), placenta (RPKM 10.8) and 1 other tissue See more Orthologs mouse all
LXN, Official Symbol LXNprovided by HGNC Official Full Name latexinprovided by HGNC Primary source HGNC:HGNC:13347 See related Ensembl:ENSG00000079257 MIM:609305; AllianceGenome:HGNC:13347 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ECI; TCI Summary This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020] Expression Ubiquitous expression in ovary (RPKM 17.1), gall bladder (RPKM 15.4) and 24 other tissues See more Orthologs mouse all
LY6D, Official Symbol LY6Dprovided by HGNC Official Full Name lymphocyte antigen 6 family member Dprovided by HGNC Primary source HGNC:HGNC:13348 See related Ensembl:ENSG00000167656 MIM:606204; AllianceGenome:HGNC:13348 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E48; Ly-6D Summary Predicted to be involved in lymphocyte differentiation. Predicted to act upstream of or within response to stilbenoid. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 212.7) and skin (RPKM 206.5) See more Orthologs mouse all
LY6E, Official Symbol LY6Eprovided by HGNC Official Full Name lymphocyte antigen 6 family member Eprovided by HGNC Primary source HGNC:HGNC:6727 See related Ensembl:ENSG00000160932 MIM:601384; AllianceGenome:HGNC:6727 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIGE; SCA2; RIG-E; SCA-2; TSA-1 Summary This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity. Expression Ubiquitous expression in liver (RPKM 110.6), spleen (RPKM 88.2) and 24 other tissues See more Orthologs mouse all
LY6G5B, Official Symbol LY6G5Bprovided by HGNC Official Full Name lymphocyte antigen 6 family member G5Bprovided by HGNC Primary source HGNC:HGNC:13931 See related Ensembl:ENSG00000240053 MIM:610433; AllianceGenome:HGNC:13931 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G5b; C6orf19 Summary LY6G5B belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in bone marrow (RPKM 22.7), skin (RPKM 15.7) and 24 other tissues See more Orthologs mouse all
LY6G5C, Official Symbol LY6G5Cprovided by HGNC Official Full Name lymphocyte antigen 6 family member G5Cprovided by HGNC Primary source HGNC:HGNC:13932 See related Ensembl:ENSG00000204428 MIM:610434; AllianceGenome:HGNC:13932 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G5C; NG33; C6orf20; LY6G5CA; LY6G5CB Summary LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 3.1), spleen (RPKM 1.6) and 25 other tissues See more Orthologs mouse all
LY6G6C, Official Symbol LY6G6Cprovided by HGNC Official Full Name lymphocyte antigen 6 family member G6Cprovided by HGNC Primary source HGNC:HGNC:13936 See related Ensembl:ENSG00000204421 MIM:610435; AllianceGenome:HGNC:13936 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G6c; NG24; C6orf24 Summary LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008] Expression Restricted expression toward skin (RPKM 160.9) See more Orthologs mouse all
LY6G6D, Official Symbol LY6G6Dprovided by HGNC Official Full Name lymphocyte antigen 6 family member G6Dprovided by HGNC Primary source HGNC:HGNC:13935 See related Ensembl:ENSG00000244355 MIM:606038; AllianceGenome:HGNC:13935 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G6D; NG25; LY6-D; MEGT1; C6orf23 Summary LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Apr 2009] Expression Biased expression in prostate (RPKM 1.8), testis (RPKM 1.5) and 6 other tissues See more Orthologs mouse all
LY6G6F, Official Symbol LY6G6Fprovided by HGNC Official Full Name lymphocyte antigen 6 family member G6Fprovided by HGNC Primary source HGNC:HGNC:13933 See related Ensembl:ENSG00000204424 MIM:611404; AllianceGenome:HGNC:13933 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G6f; NG32; LY6G6; LY6G6D; C6orf21 Summary The human G6f protein is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which is comprised of cell-surface proteins involved in the immune system and cellular recognition (de Vet et al., 2003 [PubMed 12852788]).[supplied by OMIM, Mar 2008] Expression Biased expression in bone marrow (RPKM 1.5), testis (RPKM 1.4) and 5 other tissues See more Orthologs mouse all
LY6G6F-LY6G6D, Official Symbol LY6G6F-LY6G6Dprovided by HGNC Official Full Name LY6G6F-LY6G6D readthroughprovided by HGNC Primary source HGNC:HGNC:38821 See related Ensembl:ENSG00000250641 AllianceGenome:HGNC:38821 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEGT1; MEGT-1; G6F-LY6G6D Summary This locus represents naturally occurring readthrough transcription between the neighboring LY6G6F (lymphocyte antigen 6 family member G6F) and LY6G6D (lymphocyte antigen 6 family member G6D) genes on chromosome 6. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2017] Orthologs all
LY6H, Official Symbol LY6Hprovided by HGNC Official Full Name lymphocyte antigen 6 family member Hprovided by HGNC Primary source HGNC:HGNC:6728 See related Ensembl:ENSG00000176956 MIM:603625; AllianceGenome:HGNC:6728 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NMLY6 Summary Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 15.6), stomach (RPKM 1.2) and 1 other tissue See more Orthologs mouse all
LY6K, Official Symbol LY6Kprovided by HGNC Official Full Name lymphocyte antigen 6 family member Kprovided by HGNC Primary source HGNC:HGNC:24225 See related Ensembl:ENSG00000160886 MIM:615093; AllianceGenome:HGNC:24225 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT97; ly-6K; URLC10; HSJ001348 Summary Predicted to be involved in binding activity of sperm to zona pellucida. Predicted to act upstream of or within flagellated sperm motility. Predicted to be located in cell surface; cytoplasm; and plasma membrane. Predicted to be active in acrosomal vesicle. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 9.3), fat (RPKM 2.1) and 4 other tissues See more Orthologs mouse all
LY6L, Official Symbol LY6Lprovided by HGNC Official Full Name lymphocyte antigen 6 family member Lprovided by HGNC Primary source HGNC:HGNC:52284 See related Ensembl:ENSG00000261667 AllianceGenome:HGNC:52284 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be anchored component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
LY75, Official Symbol LY75provided by HGNC Official Full Name lymphocyte antigen 75provided by HGNC Primary source HGNC:HGNC:6729 See related Ensembl:ENSG00000054219 MIM:604524; AllianceGenome:HGNC:6729 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD205; LY-75; CLEC13B; DEC-205; GP200-MR6 Summary Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 17.2), appendix (RPKM 13.2) and 17 other tissues See more Orthologs mouse all
LY75-CD302, Official Symbol LY75-CD302provided by HGNC Official Full Name LY75-CD302 readthroughprovided by HGNC Primary source HGNC:HGNC:38828 See related Ensembl:ENSG00000248672 AllianceGenome:HGNC:38828 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LY75; CD205; Ly-75; CLEC13B; DEC-205; gp200-MR6 Summary This locus represents naturally occurring read-through transcription between the neighboring lymphocyte antigen 75 (LY75) and CD302 molecule (CD302) genes. Alternative splicing results in multiple transcript variants encoding fusion products that share sequence identity with each individual gene product. [provided by RefSeq, Nov 2010] Expression Ubiquitous expression in liver (RPKM 22.9), lung (RPKM 17.6) and 25 other tissues See more Orthologs all
LY86, Official Symbol LY86provided by HGNC Official Full Name lymphocyte antigen 86provided by HGNC Primary source HGNC:HGNC:16837 See related Ensembl:ENSG00000112799 MIM:605241; AllianceGenome:HGNC:16837 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MD1; MD-1; MMD-1; dJ80N2.1 Summary Acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lymph node (RPKM 17.5), spleen (RPKM 16.2) and 13 other tissues See more Orthologs mouse all
LY86-AS1, Official Symbol LY86-AS1provided by HGNC Official Full Name LY86 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:26593 See related Ensembl:ENSG00000216863 AllianceGenome:HGNC:26593 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LY86AS; LY86-AS Expression Biased expression in brain (RPKM 2.1), fat (RPKM 0.2) and 4 other tissues See more
LY9, Official Symbol LY9provided by HGNC Official Full Name lymphocyte antigen 9provided by HGNC Primary source HGNC:HGNC:6730 See related Ensembl:ENSG00000122224 MIM:600684; AllianceGenome:HGNC:6730 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hly9; mLY9; CD229; SLAMF3 Summary LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008] Expression Biased expression in lymph node (RPKM 6.9), spleen (RPKM 5.2) and 11 other tissues See more Orthologs mouse all
LY96, Official Symbol LY96provided by HGNC Official Full Name lymphocyte antigen 96provided by HGNC Primary source HGNC:HGNC:17156 See related Ensembl:ENSG00000154589 MIM:605243; AllianceGenome:HGNC:17156 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MD2; MD-2; ly-96; ESOP-1 Summary This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010] Expression Broad expression in spleen (RPKM 8.6), appendix (RPKM 8.4) and 22 other tissues See more Orthologs mouse all
LYAR, Official Symbol LYARprovided by HGNC Official Full Name Ly1 antibody reactiveprovided by HGNC Primary source HGNC:HGNC:26021 See related Ensembl:ENSG00000145220 MIM:617684; AllianceGenome:HGNC:26021 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZLYAR; ZC2HC2 Summary Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 46.8), lymph node (RPKM 8.5) and 20 other tissues See more Orthologs mouse all
LYARP1, Official Symbol LYARP1provided by HGNC Official Full Name Ly1 antibody reactive pseudogene 1provided by HGNC Primary source HGNC:HGNC:50747 See related AllianceGenome:HGNC:50747 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
LYG1, Official Symbol LYG1provided by HGNC Official Full Name lysozyme g1provided by HGNC Primary source HGNC:HGNC:27014 See related Ensembl:ENSG00000144214 AllianceGenome:HGNC:27014 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYGA1; SALW1939 Summary Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 2.5), testis (RPKM 0.7) and 11 other tissues See more Orthologs mouse all
LYG2, Official Symbol LYG2provided by HGNC Official Full Name lysozyme g2provided by HGNC Primary source HGNC:HGNC:29615 See related Ensembl:ENSG00000185674 MIM:616547; AllianceGenome:HGNC:29615 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYGH; LYGA2; LYSG2 Summary The protein encoded by this gene contains a SLT domain, a protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
LYL1, Official Symbol LYL1provided by HGNC Official Full Name LYL1 basic helix-loop-helix family memberprovided by HGNC Primary source HGNC:HGNC:6734 See related Ensembl:ENSG00000104903 MIM:151440; AllianceGenome:HGNC:6734 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as bHLHa18 Summary This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010] Expression Broad expression in bone marrow (RPKM 7.8), spleen (RPKM 5.8) and 18 other tissues See more Orthologs mouse all
LYN, Official Symbol LYNprovided by HGNC Official Full Name LYN proto-oncogene, Src family tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:6735 See related Ensembl:ENSG00000254087 MIM:165120; AllianceGenome:HGNC:6735 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JTK8; SAIDV; p53Lyn; p56Lyn Summary This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] Expression Broad expression in spleen (RPKM 32.6), appendix (RPKM 29.7) and 20 other tissues See more Orthologs mouse all
LYNX1, Official Symbol LYNX1provided by HGNC Official Full Name Ly6/neurotoxin 1provided by HGNC Primary source HGNC:HGNC:29604 See related Ensembl:ENSG00000180155 MIM:606110; AllianceGenome:HGNC:29604 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a GPI-anchored, cell membrane bound member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This protein interacts with nicotinic acetylcholine receptors (nAChRs), and is thought to function as a modulator of nAChR activity to prevent excessive excitation. Alternatively spliced transcript variants have been found for this gene. Read-through transcription between this gene and the neighboring downstream gene (SLURP2) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017] Expression Broad expression in brain (RPKM 28.8), heart (RPKM 21.3) and 18 other tissues See more Orthologs mouse all
LYNX1-SLURP2, Official Symbol LYNX1-SLURP2provided by HGNC Official Full Name LYNX1-SLURP2 readthroughprovided by HGNC Primary source HGNC:HGNC:52291 See related Ensembl:ENSG00000284505 AllianceGenome:HGNC:52291 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring read-through transcription between the neighboring LYNX1 and SLURP2 genes. The readthrough transcript encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The significance of this read-through transcription and the function of the resulting protein product have not yet been determined. [provided by RefSeq, Sep 2017] Orthologs all
LYPD1, Official Symbol LYPD1provided by HGNC Official Full Name LY6/PLAUR domain containing 1provided by HGNC Primary source HGNC:HGNC:28431 See related Ensembl:ENSG00000150551 MIM:610450; AllianceGenome:HGNC:28431 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHTS; LYPDC1 Summary Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to act upstream of or within several processes, including behavioral fear response; cholinergic synaptic transmission; and negative regulation of protein localization to plasma membrane. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 4.3), colon (RPKM 1.3) and 16 other tissues See more Orthologs mouse all
LYPD2, Official Symbol LYPD2provided by HGNC Official Full Name LY6/PLAUR domain containing 2provided by HGNC Primary source HGNC:HGNC:25215 See related Ensembl:ENSG00000197353 AllianceGenome:HGNC:25215 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYPDC2; UNQ430 Summary Predicted to be located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 24.8), stomach (RPKM 10.7) and 1 other tissue See more Orthologs mouse all
LYPD3, Official Symbol LYPD3provided by HGNC Official Full Name LY6/PLAUR domain containing 3provided by HGNC Primary source HGNC:HGNC:24880 See related Ensembl:ENSG00000124466 MIM:609484; AllianceGenome:HGNC:24880 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C4.4A Summary Predicted to enable laminin binding activity. Predicted to act upstream of or within cell-matrix adhesion. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 319.1) and skin (RPKM 226.0) See more Orthologs mouse all
LYPD4, Official Symbol LYPD4provided by HGNC Official Full Name LY6/PLAUR domain containing 4provided by HGNC Primary source HGNC:HGNC:28659 See related Ensembl:ENSG00000273111 AllianceGenome:HGNC:28659 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMR Summary Predicted to be located in extracellular region and plasma membrane. Predicted to be active in plasma membrane raft. Predicted to be anchored component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 27.7) See more Orthologs mouse all
LYPD5, Official Symbol LYPD5provided by HGNC Official Full Name LY6/PLAUR domain containing 5provided by HGNC Primary source HGNC:HGNC:26397 See related Ensembl:ENSG00000159871 MIM:619618; AllianceGenome:HGNC:26397 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO4356; HALDISIN Summary Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 12.1), brain (RPKM 2.5) and 5 other tissues See more Orthologs mouse all
LYPD6, Official Symbol LYPD6provided by HGNC Official Full Name LY6/PLAUR domain containing 6provided by HGNC Primary source HGNC:HGNC:28751 See related Ensembl:ENSG00000187123 MIM:613359; AllianceGenome:HGNC:28751 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Members of the LY6 protein family (see SLURP1; MIM 606119), such as LYPD6, have at least one 80-amino acid LU domain that contains 10 conserved cysteines with a defined disulfide-bonding pattern (Zhang et al., 2010 [PubMed 19653121]).[supplied by OMIM, Apr 2010] Expression Biased expression in gall bladder (RPKM 7.3), placenta (RPKM 6.8) and 12 other tissues See more Orthologs mouse all
LYPD6B, Official Symbol LYPD6Bprovided by HGNC Official Full Name LY6/PLAUR domain containing 6Bprovided by HGNC Primary source HGNC:HGNC:27018 See related Ensembl:ENSG00000150556 AllianceGenome:HGNC:27018 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT116; LYPD7 Summary Enables acetylcholine receptor regulator activity. Predicted to be located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in gall bladder (RPKM 13.0), skin (RPKM 12.7) and 8 other tissues See more Orthologs mouse all
LYPD8, Official Symbol LYPD8provided by HGNC Official Full Name LY6/PLAUR domain containing 8provided by HGNC Primary source HGNC:HGNC:44208 See related Ensembl:ENSG00000259823 MIM:617067; AllianceGenome:HGNC:44208 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward colon (RPKM 65.3) See more Orthologs mouse all
LYPLA1, Official Symbol LYPLA1provided by HGNC Official Full Name lysophospholipase 1provided by HGNC Primary source HGNC:HGNC:6737 See related Ensembl:ENSG00000120992 MIM:605599; AllianceGenome:HGNC:6737 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APT1; LPL1; APT-1; LPL-I; hAPT1 Summary This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in urinary bladder (RPKM 38.7), testis (RPKM 35.4) and 25 other tissues See more Orthologs mouse all
LYPLA2, Official Symbol LYPLA2provided by HGNC Official Full Name lysophospholipase 2provided by HGNC Primary source HGNC:HGNC:6738 See related Ensembl:ENSG00000011009 MIM:616143; AllianceGenome:HGNC:6738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APT2; APT-2; DJ886K2.4 Summary Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in placenta (RPKM 17.1), duodenum (RPKM 15.8) and 25 other tissues See more Orthologs mouse all
LYPLAL1, Official Symbol LYPLAL1provided by HGNC Official Full Name lysophospholipase like 1provided by HGNC Primary source HGNC:HGNC:20440 See related Ensembl:ENSG00000143353 MIM:616548; AllianceGenome:HGNC:20440 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Q96AV0 Summary Predicted to enable carboxylic ester hydrolase activity and palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation. Predicted to act upstream of or within negative regulation of Golgi to plasma membrane protein transport. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 3.2), heart (RPKM 2.4) and 25 other tissues See more Orthologs mouse all
LYPLAL1-AS1, Official Symbol LYPLAL1-AS1provided by HGNC Official Full Name LYPLAL1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:54054 See related AllianceGenome:HGNC:54054 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 2.1), endometrium (RPKM 0.4) and 2 other tissues See more
LYPLAL1-DT, Official Symbol LYPLAL1-DTprovided by HGNC Official Full Name LYPLAL1 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:50560 See related Ensembl:ENSG00000228063 AllianceGenome:HGNC:50560 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYPLAL1-AS1 Expression Low expression observed in reference dataset See more
LYRM1, Official Symbol LYRM1provided by HGNC Official Full Name LYR motif containing 1provided by HGNC Primary source HGNC:HGNC:25074 See related Ensembl:ENSG00000102897 MIM:614709; AllianceGenome:HGNC:25074 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A211C6.1 Summary The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Ubiquitous expression in liver (RPKM 13.3), fat (RPKM 11.4) and 25 other tissues See more Orthologs mouse all
LYRM2, Official Symbol LYRM2provided by HGNC Official Full Name LYR motif containing 2provided by HGNC Primary source HGNC:HGNC:25229 See related Ensembl:ENSG00000083099 AllianceGenome:HGNC:25229 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DJ122O8.2 Expression Ubiquitous expression in brain (RPKM 12.5), thyroid (RPKM 12.1) and 25 other tissues See more Orthologs mouse all
LYRM4, Official Symbol LYRM4provided by HGNC Official Full Name LYR motif containing 4provided by HGNC Primary source HGNC:HGNC:21365 See related Ensembl:ENSG00000214113 MIM:613311; AllianceGenome:HGNC:21365 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISD11; CGI-203; COXPD19; C6orf149 Summary The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in ovary (RPKM 2.3), thyroid (RPKM 2.1) and 25 other tissues See more Orthologs mouse all
LYRM4-AS1, Official Symbol LYRM4-AS1provided by HGNC Official Full Name LYRM4 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:52055 See related Ensembl:ENSG00000272142 AllianceGenome:HGNC:52055 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 1.1), adrenal (RPKM 0.7) and 23 other tissues See more
LYRM7, Official Symbol LYRM7provided by HGNC Official Full Name LYR motif containing 7provided by HGNC Primary source HGNC:HGNC:28072 See related Ensembl:ENSG00000186687 MIM:615831; AllianceGenome:HGNC:28072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MZM1L; MC3DN8; C5orf31 Summary Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] Expression Ubiquitous expression in brain (RPKM 5.8), thyroid (RPKM 4.7) and 24 other tissues See more Orthologs mouse all
LYRM9, Official Symbol LYRM9provided by HGNC Official Full Name LYR motif containing 9provided by HGNC Primary source HGNC:HGNC:27314 See related Ensembl:ENSG00000232859 AllianceGenome:HGNC:27314 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSD24; C17orf108 Expression Ubiquitous expression in thyroid (RPKM 12.9), brain (RPKM 12.4) and 25 other tissues See more Orthologs mouse all
LYSMD1, Official Symbol LYSMD1provided by HGNC Official Full Name LysM domain containing 1provided by HGNC Primary source HGNC:HGNC:32070 See related Ensembl:ENSG00000163155 AllianceGenome:HGNC:32070 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SB145 Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 7.3), lymph node (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
LYSMD2, Official Symbol LYSMD2provided by HGNC Official Full Name LysM domain containing 2provided by HGNC Primary source HGNC:HGNC:28571 See related Ensembl:ENSG00000140280 AllianceGenome:HGNC:28571 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in brain (RPKM 8.4), lymph node (RPKM 8.3) and 25 other tissues See more Orthologs mouse all
LYSMD3, Official Symbol LYSMD3provided by HGNC Official Full Name LysM domain containing 3provided by HGNC Primary source HGNC:HGNC:26969 See related Ensembl:ENSG00000176018 AllianceGenome:HGNC:26969 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Involved in Golgi organization. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 11.6), adrenal (RPKM 8.4) and 25 other tissues See more Orthologs mouse all
LYSMD4, Official Symbol LYSMD4provided by HGNC Official Full Name LysM domain containing 4provided by HGNC Primary source HGNC:HGNC:26571 See related Ensembl:ENSG00000183060 AllianceGenome:HGNC:26571 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 10.8), endometrium (RPKM 9.0) and 25 other tissues See more Orthologs mouse all
LYST, Official Symbol LYSTprovided by HGNC Official Full Name lysosomal trafficking regulatorprovided by HGNC Primary source HGNC:HGNC:1968 See related Ensembl:ENSG00000143669 MIM:606897; AllianceGenome:HGNC:1968 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHS; CHS1; Mauve Summary This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013] Expression Broad expression in bone marrow (RPKM 12.2), skin (RPKM 4.6) and 24 other tissues See more Orthologs mouse all
LYST-AS1, Official Symbol LYST-AS1provided by HGNC Official Full Name LYST antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41320 See related AllianceGenome:HGNC:41320 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYST-IT2 Annotation information not in current annotation release
LYVE1, Official Symbol LYVE1provided by HGNC Official Full Name lymphatic vessel endothelial hyaluronan receptor 1provided by HGNC Primary source HGNC:HGNC:14687 See related Ensembl:ENSG00000133800 MIM:605702; AllianceGenome:HGNC:14687 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HAR; XLKD1; LYVE-1; CRSBP-1 Summary This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 141.7), adrenal (RPKM 68.8) and 14 other tissues See more Orthologs mouse all