psui3905/ncbi_genes_summary huggingface dataset:
RHD, Official Symbol RHDprovided by HGNC Official Full Name Rh blood group D antigenprovided by HGNC Primary source HGNC:HGNC:10009 See related Ensembl:ENSG00000187010 MIM:111680; AllianceGenome:HGNC:10009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RH; Rh4; RH30; RhII; RhPI; DIIIc; RHCED; RHDel; RHPII; RhDCw; CD240D; HDFNRH; RHXIII; RHDVA(TT); RhK562-II Summary The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 5.0), skin (RPKM 0.4) and 2 other tissues See more
RHEB, Official Symbol RHEBprovided by HGNC Official Full Name Ras homolog, mTORC1 bindingprovided by HGNC Primary source HGNC:HGNC:10011 See related Ensembl:ENSG00000106615 MIM:601293; AllianceGenome:HGNC:10011 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHEB2 Summary This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 38.1), brain (RPKM 36.3) and 25 other tissues See more Orthologs mouse all
RHEBL1, Official Symbol RHEBL1provided by HGNC Official Full Name RHEB like 1provided by HGNC Primary source HGNC:HGNC:21166 See related Ensembl:ENSG00000167550 MIM:618956; AllianceGenome:HGNC:21166 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHEBL1c Summary Enables GTP binding activity. Involved in TOR signaling and positive regulation of NF-kappaB transcription factor activity. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
RHEX, Official Symbol RHEXprovided by HGNC Official Full Name regulator of hemoglobinization and erythroid cell expansionprovided by HGNC Primary source HGNC:HGNC:25341 See related Ensembl:ENSG00000263961 MIM:616088; AllianceGenome:HGNC:25341 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf186 Summary Enables erythropoietin receptor binding activity. Involved in erythropoietin-mediated signaling pathway and positive regulation of erythrocyte differentiation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 4.0), gall bladder (RPKM 2.3) and 16 other tissues See more Orthologs all
RHNO1, Official Symbol RHNO1provided by HGNC Official Full Name RAD9-HUS1-RAD1 interacting nuclear orphan 1provided by HGNC Primary source HGNC:HGNC:28206 See related Ensembl:ENSG00000171792 MIM:614085; AllianceGenome:HGNC:28206 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHINO; C12orf32; HKMT1188 Summary Involved in cellular response to radiation; recombinational repair; and regulation of cell cycle process. Located in chromosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 7.6), lymph node (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
RHO, Official Symbol RHOprovided by HGNC Official Full Name rhodopsinprovided by HGNC Primary source HGNC:HGNC:10012 See related Ensembl:ENSG00000163914 MIM:180380; AllianceGenome:HGNC:10012 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP4; OPN2; CSNBAD1 Summary The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness. [provided by RefSeq, Aug 2017] Expression Low expression observed in reference dataset See more Orthologs mouse all
RHOA, Official Symbol RHOAprovided by HGNC Official Full Name ras homolog family member Aprovided by HGNC Primary source HGNC:HGNC:667 See related Ensembl:ENSG00000067560 MIM:165390; AllianceGenome:HGNC:667 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHA; ARH12; RHO12; EDFAOB; RHOH12 Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] Expression Ubiquitous expression in fat (RPKM 218.4), lung (RPKM 210.7) and 25 other tissues See more Orthologs mouse all
RHOB, Official Symbol RHOBprovided by HGNC Official Full Name ras homolog family member Bprovided by HGNC Primary source HGNC:HGNC:668 See related Ensembl:ENSG00000143878 MIM:165370; AllianceGenome:HGNC:668 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARH6; ARHB; RHOH6; MST081; MSTP081 Summary Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
RHOBTB1, Official Symbol RHOBTB1provided by HGNC Official Full Name Rho related BTB domain containing 1provided by HGNC Primary source HGNC:HGNC:18738 See related Ensembl:ENSG00000072422 MIM:607351; AllianceGenome:HGNC:18738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] Expression Broad expression in placenta (RPKM 10.3), kidney (RPKM 7.3) and 22 other tissues See more Orthologs mouse all
RHOBTB2, Official Symbol RHOBTB2provided by HGNC Official Full Name Rho related BTB domain containing 2provided by HGNC Primary source HGNC:HGNC:18756 See related Ensembl:ENSG00000008853 MIM:607352; AllianceGenome:HGNC:18756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p83; DBC2; DEE64; EIEE64 Summary The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in lung (RPKM 11.1), brain (RPKM 8.7) and 22 other tissues See more Orthologs mouse all
RHOBTB3, Official Symbol RHOBTB3provided by HGNC Official Full Name Rho related BTB domain containing 3provided by HGNC Primary source HGNC:HGNC:18757 See related Ensembl:ENSG00000164292 MIM:607353; AllianceGenome:HGNC:18757 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ATP binding activity and small GTPase binding activity. Involved in retrograde transport, endosome to Golgi. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 37.7), ovary (RPKM 32.7) and 24 other tissues See more Orthologs mouse all
RHOC, Official Symbol RHOCprovided by HGNC Official Full Name ras homolog family member Cprovided by HGNC Primary source HGNC:HGNC:669 See related Ensembl:ENSG00000155366 MIM:165380; AllianceGenome:HGNC:669 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H9; ARH9; ARHC; RHOH9 Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 99.1), small intestine (RPKM 91.0) and 24 other tissues See more Orthologs mouse all
RHOD, Official Symbol RHODprovided by HGNC Official Full Name ras homolog family member Dprovided by HGNC Primary source HGNC:HGNC:670 See related Ensembl:ENSG00000173156 MIM:605781; AllianceGenome:HGNC:670 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Rho; ARHD; RHOM; RHOHP1 Summary Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in esophagus (RPKM 14.1), skin (RPKM 7.1) and 20 other tissues See more Orthologs mouse all
RHOF, Official Symbol RHOFprovided by HGNC Official Full Name ras homolog family member F, filopodia associatedprovided by HGNC Primary source HGNC:HGNC:15703 See related Ensembl:ENSG00000139725 MIM:618867; AllianceGenome:HGNC:15703 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIF; ARHF Summary Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in actin filament organization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 15.7), bone marrow (RPKM 15.5) and 23 other tissues See more Orthologs mouse all
RHOG, Official Symbol RHOGprovided by HGNC Official Full Name ras homolog family member Gprovided by HGNC Primary source HGNC:HGNC:672 See related Ensembl:ENSG00000177105 MIM:179505; AllianceGenome:HGNC:672 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHG Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011] Expression Broad expression in bone marrow (RPKM 74.8), spleen (RPKM 41.3) and 24 other tissues See more Orthologs mouse all
RHOG2P, Official Symbol RHOG2Pprovided by HGNC Official Full Name RHOG family member 2, pseudogeneprovided by HGNC Primary source HGNC:HGNC:54953 See related Ensembl:ENSG00000213706 AllianceGenome:HGNC:54953 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RHOH, Official Symbol RHOHprovided by HGNC Official Full Name ras homolog family member Hprovided by HGNC Primary source HGNC:HGNC:686 See related Ensembl:ENSG00000168421 MIM:602037; AllianceGenome:HGNC:686 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTF; ARHH Summary The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013] Expression Biased expression in lymph node (RPKM 20.2), bone marrow (RPKM 10.8) and 8 other tissues See more Orthologs mouse all
RHOJ, Official Symbol RHOJprovided by HGNC Official Full Name ras homolog family member Jprovided by HGNC Primary source HGNC:HGNC:688 See related Ensembl:ENSG00000126785 MIM:607653; AllianceGenome:HGNC:688 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCL; ARHJ; TC10B; RASL7B Summary This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011] Expression Ubiquitous expression in gall bladder (RPKM 9.9), lung (RPKM 9.2) and 23 other tissues See more Orthologs mouse all
RHOQ, Official Symbol RHOQprovided by HGNC Official Full Name ras homolog family member Qprovided by HGNC Primary source HGNC:HGNC:17736 See related Ensembl:ENSG00000119729 MIM:605857; AllianceGenome:HGNC:17736 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHQ; TC10; TC10A; RASL7A; HEL-S-42 Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in fat (RPKM 72.1), heart (RPKM 55.0) and 24 other tissues See more Orthologs mouse all
RHOQ-AS1, Official Symbol RHOQ-AS1provided by HGNC Official Full Name RHOQ antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40816 See related Ensembl:ENSG00000250116 AllianceGenome:HGNC:40816 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 2.2), appendix (RPKM 0.7) and 13 other tissues See more
RHOT1, Official Symbol RHOT1provided by HGNC Official Full Name ras homolog family member T1provided by HGNC Primary source HGNC:HGNC:21168 See related Ensembl:ENSG00000126858 MIM:613888; AllianceGenome:HGNC:21168 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHT1; MIRO1; MIRO-1 Summary Predicted to enable GTP binding activity and GTPase activity. Involved in cellular homeostasis; mitochondrial outer membrane permeabilization; and mitochondrion transport along microtubule. Is integral component of mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 9.0), thyroid (RPKM 8.7) and 25 other tissues See more Orthologs mouse all
RHOT1P1, Official Symbol RHOT1P1provided by HGNC Official Full Name ras homolog family member T1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:23777 See related Ensembl:ENSG00000266145 AllianceGenome:HGNC:23777 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHOT3; RHOT1P
RHOT2, Official Symbol RHOT2provided by HGNC Official Full Name ras homolog family member T2provided by HGNC Primary source HGNC:HGNC:21169 See related Ensembl:ENSG00000140983 MIM:613889; AllianceGenome:HGNC:21169 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RASL; ARHT2; MIRO2; MIRO-2; C16orf39 Summary This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in spleen (RPKM 20.5), duodenum (RPKM 16.0) and 25 other tissues See more Orthologs mouse all
RHOU, Official Symbol RHOUprovided by HGNC Official Full Name ras homolog family member Uprovided by HGNC Primary source HGNC:HGNC:17794 See related Ensembl:ENSG00000116574 MIM:606366; AllianceGenome:HGNC:17794 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHU; G28K; WRCH1; hG28K; CDC42L1 Summary This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011] Expression Ubiquitous expression in brain (RPKM 24.2), small intestine (RPKM 22.4) and 25 other tissues See more Orthologs mouse all
RHOV, Official Symbol RHOVprovided by HGNC Official Full Name ras homolog family member Vprovided by HGNC Primary source HGNC:HGNC:18313 See related Ensembl:ENSG00000104140 MIM:620101; AllianceGenome:HGNC:18313 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHP; ARHV; WRCH2 Summary Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in several processes, including Cdc42 protein signal transduction; cell projection assembly; and endocytosis. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 34.6), skin (RPKM 27.2) and 5 other tissues See more Orthologs mouse all
RHOXF1, Official Symbol RHOXF1provided by HGNC Official Full Name Rhox homeobox family member 1provided by HGNC Primary source HGNC:HGNC:29993 See related Ensembl:ENSG00000101883 MIM:300446; AllianceGenome:HGNC:29993 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OTEX; PEPP1 Summary This gene is a member of the PEPP subfamily of paired-like homoebox genes. The gene may be regulated by androgens and epigenetic mechanisms. The encoded nuclear protein is likely a transcription factor that may play a role in human reproduction. [provided by RefSeq, Dec 2012] Expression Biased expression in testis (RPKM 4.9), fat (RPKM 1.1) and 2 other tissues See more Orthologs all
RHOXF1-AS1, Official Symbol RHOXF1-AS1provided by HGNC Official Full Name RHOXF1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:51582 See related Ensembl:ENSG00000258545 AllianceGenome:HGNC:51582 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in fat (RPKM 5.7), lung (RPKM 1.8) and 5 other tissues See more
RHOXF1P1, Official Symbol RHOXF1P1provided by HGNC Official Full Name Rhox homeobox family member 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:51580 See related Ensembl:ENSG00000291200 MIM:300973; AllianceGenome:HGNC:51580 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as lncRHOXF1; TCONS_00017086 Expression Biased expression in pancreas (RPKM 2.5), adrenal (RPKM 0.8) and 1 other tissue See more
RHOXF2, Official Symbol RHOXF2provided by HGNC Official Full Name Rhox homeobox family member 2provided by HGNC Primary source HGNC:HGNC:30011 See related Ensembl:ENSG00000131721 MIM:300447; AllianceGenome:HGNC:30011 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as THG1; CT107; PEPP2; PEPP-2 Summary This gene, which encodes a transcriptional repressor, is one of two paralogous X-linked homeobox-containing genes and is highly expressed in a variety of cancers. In addition, the encoded protein associates with the cell membrane and with microtubules, and is concentrated at the leading edge of migratory cells. [provided by RefSeq, Dec 2015] Expression Restricted expression toward testis (RPKM 22.1) See more Orthologs all
RHOXF2B, Official Symbol RHOXF2Bprovided by HGNC Official Full Name Rhox homeobox family member 2Bprovided by HGNC Primary source HGNC:HGNC:33519 See related Ensembl:ENSG00000203989 AllianceGenome:HGNC:33519 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 19.7) See more Orthologs all
RHPN1, Official Symbol RHPN1provided by HGNC Official Full Name rhophilin Rho GTPase binding protein 1provided by HGNC Primary source HGNC:HGNC:19973 See related Ensembl:ENSG00000158106 MIM:601031; AllianceGenome:HGNC:19973 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ODF5; RHPN; RHOPHILIN Summary Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including focal adhesion assembly; glomerular filtration; and negative regulation of stress fiber assembly. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 2.9), kidney (RPKM 2.5) and 22 other tissues See more Orthologs mouse all
RHPN1-AS1, Official Symbol RHPN1-AS1provided by HGNC Official Full Name RHPN1 antisense RNA 1 (head to head)provided by HGNC Primary source HGNC:HGNC:28457 See related Ensembl:ENSG00000254389 AllianceGenome:HGNC:28457 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8orf51
RHPN2, Official Symbol RHPN2provided by HGNC Official Full Name rhophilin Rho GTPase binding protein 2provided by HGNC Primary source HGNC:HGNC:19974 See related Ensembl:ENSG00000131941 MIM:617932; AllianceGenome:HGNC:19974 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHOBP; P76RBE Summary This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009] Expression Broad expression in colon (RPKM 18.4), prostate (RPKM 16.3) and 16 other tissues See more Orthologs mouse all
RIBC1, Official Symbol RIBC1provided by HGNC Official Full Name RIB43A domain with coiled-coils 1provided by HGNC Primary source HGNC:HGNC:26537 See related Ensembl:ENSG00000158423 AllianceGenome:HGNC:26537 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2610028I09Rik Expression Biased expression in testis (RPKM 7.7), lung (RPKM 1.1) and 5 other tissues See more Orthologs mouse all
RIBC2, Official Symbol RIBC2provided by HGNC Official Full Name RIB43A domain with coiled-coils 2provided by HGNC Primary source HGNC:HGNC:13241 See related Ensembl:ENSG00000128408 AllianceGenome:HGNC:13241 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIB; C22orf11 Summary Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 10.0) and bone marrow (RPKM 0.7) See more Orthologs mouse all
RIC1, Official Symbol RIC1provided by HGNC Official Full Name RIC1 homolog, RAB6A GEF complex partner 1provided by HGNC Primary source HGNC:HGNC:17686 See related Ensembl:ENSG00000107036 MIM:610354; AllianceGenome:HGNC:17686 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CATIFA; CIP150; KIAA1432; bA207C16.1 Summary Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including positive regulation of GTPase activity; regulation of extracellular matrix constituent secretion; and retrograde transport, endosome to Golgi. Located in cytosol and membrane. Part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 6.0), testis (RPKM 5.0) and 25 other tissues See more Orthologs mouse all
RIC3, Official Symbol RIC3provided by HGNC Official Full Name RIC3 acetylcholine receptor chaperoneprovided by HGNC Primary source HGNC:HGNC:30338 See related Ensembl:ENSG00000166405 MIM:610509; AllianceGenome:HGNC:30338 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIC-3; AYST720; PRO1385 Summary This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in brain (RPKM 6.2), prostate (RPKM 4.2) and 23 other tissues See more Orthologs mouse all
RIC3-DT, Official Symbol RIC3-DTprovided by HGNC Official Full Name RIC3 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:54191 See related AllianceGenome:HGNC:54191 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
RIC8A, Official Symbol RIC8Aprovided by HGNC Official Full Name RIC8 guanine nucleotide exchange factor Aprovided by HGNC Primary source HGNC:HGNC:29550 See related Ensembl:ENSG00000177963 MIM:609146; AllianceGenome:HGNC:29550 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIC8 Summary Predicted to enable G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 20.2), brain (RPKM 15.3) and 25 other tissues See more Orthologs mouse all
RIC8B, Official Symbol RIC8Bprovided by HGNC Official Full Name RIC8 guanine nucleotide exchange factor Bprovided by HGNC Primary source HGNC:HGNC:25555 See related Ensembl:ENSG00000111785 MIM:609147; AllianceGenome:HGNC:25555 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIC8; hSyn Summary Enables G-protein alpha-subunit binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 2.6), gall bladder (RPKM 2.0) and 25 other tissues See more Orthologs mouse all
RICTOR, Official Symbol RICTORprovided by HGNC Official Full Name RPTOR independent companion of MTOR complex 2provided by HGNC Primary source HGNC:HGNC:28611 See related Ensembl:ENSG00000164327 MIM:609022; AllianceGenome:HGNC:28611 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIA; AVO3; hAVO3 Summary RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in bone marrow (RPKM 9.8), testis (RPKM 7.0) and 25 other tissues See more Orthologs mouse all
RIDA, Official Symbol RIDAprovided by HGNC Official Full Name reactive intermediate imine deaminase A homologprovided by HGNC Primary source HGNC:HGNC:16897 See related Ensembl:ENSG00000132541 MIM:602487; AllianceGenome:HGNC:16897 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSP; P14.5; UK114; HRSP12; hp14.5 Summary Enables 2-iminobutanoate deaminase activity and mRNA binding activity. Involved in mRNA catabolic process; mRNA destabilization; and organonitrogen compound catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in liver (RPKM 363.6), kidney (RPKM 202.2) and 3 other tissues See more Orthologs mouse all
RIF1, Official Symbol RIF1provided by HGNC Official Full Name replication timing regulatory factor 1provided by HGNC Primary source HGNC:HGNC:23207 See related Ensembl:ENSG00000080345 MIM:608952; AllianceGenome:HGNC:23207 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein that shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. This protein localizes to aberrant telomeres may be involved in DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] Expression Ubiquitous expression in bone marrow (RPKM 5.5), testis (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
RIIAD1, Official Symbol RIIAD1provided by HGNC Official Full Name regulatory subunit of type II PKA R-subunit domain containing 1provided by HGNC Primary source HGNC:HGNC:26686 See related Ensembl:ENSG00000178796 AllianceGenome:HGNC:26686 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf230; NCRNA00166 Expression Biased expression in testis (RPKM 5.0), brain (RPKM 1.9) and 5 other tissues See more Orthologs mouse all
RILP, Official Symbol RILPprovided by HGNC Official Full Name Rab interacting lysosomal proteinprovided by HGNC Primary source HGNC:HGNC:30266 See related Ensembl:ENSG00000167705 MIM:607848; AllianceGenome:HGNC:30266 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP10141 Summary This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in fat (RPKM 11.4), duodenum (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
RILPL1, Official Symbol RILPL1provided by HGNC Official Full Name Rab interacting lysosomal protein like 1provided by HGNC Primary source HGNC:HGNC:26814 See related Ensembl:ENSG00000188026 MIM:614092; AllianceGenome:HGNC:26814 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RLP1; OPDM4; GOSPEL Summary Predicted to enable protein dimerization activity. Predicted to be involved in several processes, including cilium assembly; epithelial cell morphogenesis; and protein transport from ciliary membrane to plasma membrane. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in heart (RPKM 11.5), thyroid (RPKM 5.2) and 23 other tissues See more Orthologs mouse all
RILPL2, Official Symbol RILPL2provided by HGNC Official Full Name Rab interacting lysosomal protein like 2provided by HGNC Primary source HGNC:HGNC:28787 See related Ensembl:ENSG00000150977 MIM:614093; AllianceGenome:HGNC:28787 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RLP2 Summary This gene encodes a protein that contains a rab-interacting lysosomal protein-like domain. This protein may be involved in regulating lysosome morphology. This protein may also be a target for the Hepatitis C virus and assist in viral replication. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Ubiquitous expression in bone marrow (RPKM 15.2), thyroid (RPKM 7.3) and 24 other tissues See more Orthologs mouse all
RIMBP2, Official Symbol RIMBP2provided by HGNC Official Full Name RIMS binding protein 2provided by HGNC Primary source HGNC:HGNC:30339 See related Ensembl:ENSG00000060709 MIM:611602; AllianceGenome:HGNC:30339 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RBP2; RIM-BP2; PPP1R133 Summary Predicted to be involved in neuromuscular synaptic transmission. Predicted to be located in plasma membrane and synapse. Predicted to be active in presynaptic active zone cytoplasmic component. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 6.7), adrenal (RPKM 4.2) and 9 other tissues See more Orthologs mouse all
RIMBP3, Official Symbol RIMBP3provided by HGNC Official Full Name RIMS binding protein 3provided by HGNC Primary source HGNC:HGNC:29344 See related Ensembl:ENSG00000275793 MIM:612699; AllianceGenome:HGNC:29344 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIM-BP3; RIMBP3A; RIMBP3.1; RIM-BP3.1; RIM-BP3.A Summary Predicted to enable benzodiazepine receptor binding activity. Predicted to be involved in fertilization and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Predicted to colocalize with manchette. [provided by Alliance of Genome Resources, Apr 2022]
RIMBP3B, Official Symbol RIMBP3Bprovided by HGNC Official Full Name RIMS binding protein 3Bprovided by HGNC Primary source HGNC:HGNC:33891 See related Ensembl:ENSG00000274600 MIM:612700; AllianceGenome:HGNC:33891 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIMBP3.2; RIM-BP3.2; RIM-BP3.B Summary Predicted to enable benzodiazepine receptor binding activity. Predicted to be involved in fertilization and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Predicted to colocalize with manchette. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
RIMBP3C, Official Symbol RIMBP3Cprovided by HGNC Official Full Name RIMS binding protein 3Cprovided by HGNC Primary source HGNC:HGNC:33892 See related Ensembl:ENSG00000183246 MIM:612701; AllianceGenome:HGNC:33892 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIMBP3.3; RIM-BP3.3 Summary Predicted to enable benzodiazepine receptor binding activity. Predicted to be involved in fertilization and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Predicted to colocalize with manchette. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
RIMKLA, Official Symbol RIMKLAprovided by HGNC Official Full Name ribosomal modification protein rimK like family member Aprovided by HGNC Primary source HGNC:HGNC:28725 See related Ensembl:ENSG00000177181 MIM:618949; AllianceGenome:HGNC:28725 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAAGS; FAM80A; NAAGS2; NAAGS-II Summary Predicted to enable N-acetyl-L-aspartate-L-glutamate ligase activity. Predicted to be involved in glutamine family amino acid metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 2.6), colon (RPKM 1.6) and 10 other tissues See more Orthologs mouse all
RIMKLB, Official Symbol RIMKLBprovided by HGNC Official Full Name ribosomal modification protein rimK like family member Bprovided by HGNC Primary source HGNC:HGNC:29228 See related Ensembl:ENSG00000166532 MIM:614054; AllianceGenome:HGNC:29228 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAAGS; FAM80B; NAAGS-I Summary Predicted to enable N-acetyl-L-aspartate-L-glutamate ligase activity and citrate-L-glutamate ligase activity. Predicted to be involved in glutamine family amino acid metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 13.9), testis (RPKM 12.3) and 23 other tissues See more Orthologs mouse all
RIMS1, Official Symbol RIMS1provided by HGNC Official Full Name regulating synaptic membrane exocytosis 1provided by HGNC Primary source HGNC:HGNC:17282 See related Ensembl:ENSG00000079841 MIM:606629; AllianceGenome:HGNC:17282 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIM; RIM1; CORD7; RAB3IP2 Summary The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012] Expression Biased expression in brain (RPKM 5.2), testis (RPKM 1.0) and 4 other tissues See more Orthologs mouse all