psui3905/ncbi_genes_summary huggingface dataset:
RNF141, Official Symbol RNF141provided by HGNC Official Full Name ring finger protein 141provided by HGNC Primary source HGNC:HGNC:21159 See related Ensembl:ENSG00000110315 MIM:616641; AllianceGenome:HGNC:21159 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFP26; RFP141; ZNF230 Summary The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 30.2), esophagus (RPKM 28.2) and 25 other tissues See more Orthologs mouse all
RNF144A, Official Symbol RNF144Aprovided by HGNC Official Full Name ring finger protein 144Aprovided by HGNC Primary source HGNC:HGNC:20457 See related Ensembl:ENSG00000151692 MIM:619454; AllianceGenome:HGNC:20457 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UIP4; hUIP4; RNF144; UBCE7IP4 Summary This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017] Expression Ubiquitous expression in adrenal (RPKM 4.0), endometrium (RPKM 3.6) and 24 other tissues See more Orthologs mouse all
RNF144B, Official Symbol RNF144Bprovided by HGNC Official Full Name ring finger protein 144Bprovided by HGNC Primary source HGNC:HGNC:21578 See related Ensembl:ENSG00000137393 MIM:618869; AllianceGenome:HGNC:21578 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIR2; IBRDC2; p53RFP; bA528A10.3 Summary Enables ubiquitin-protein transferase activity. Involved in negative regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Located in mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 30.0), lung (RPKM 13.0) and 20 other tissues See more Orthologs mouse all
RNF145, Official Symbol RNF145provided by HGNC Official Full Name ring finger protein 145provided by HGNC Primary source HGNC:HGNC:20853 See related Ensembl:ENSG00000145860 AllianceGenome:HGNC:20853 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lung (RPKM 33.4), gall bladder (RPKM 23.7) and 24 other tissues See more Orthologs mouse all
RNF146, Official Symbol RNF146provided by HGNC Official Full Name ring finger protein 146provided by HGNC Primary source HGNC:HGNC:21336 See related Ensembl:ENSG00000118518 MIM:612137; AllianceGenome:HGNC:21336 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Involved in positive regulation of canonical Wnt signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 18.0), lung (RPKM 11.1) and 25 other tissues See more Orthologs mouse all
RNF148, Official Symbol RNF148provided by HGNC Official Full Name ring finger protein 148provided by HGNC Primary source HGNC:HGNC:22411 See related Ensembl:ENSG00000235631 AllianceGenome:HGNC:22411 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and late endosome. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
RNF149, Official Symbol RNF149provided by HGNC Official Full Name ring finger protein 149provided by HGNC Primary source HGNC:HGNC:23137 See related Ensembl:ENSG00000163162 AllianceGenome:HGNC:23137 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DNAPTP2 Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 14.1), appendix (RPKM 12.5) and 25 other tissues See more Orthologs mouse all
RNF14P2, Official Symbol RNF14P2provided by HGNC Official Full Name RNF14 pseudogene 2provided by HGNC Primary source HGNC:HGNC:54670 See related Ensembl:ENSG00000250594 AllianceGenome:HGNC:54670 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RNF14P3, Official Symbol RNF14P3provided by HGNC Official Full Name RNF14 pseudogene 3provided by HGNC Primary source HGNC:HGNC:54671 See related Ensembl:ENSG00000238109 AllianceGenome:HGNC:54671 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RNF14P4, Official Symbol RNF14P4provided by HGNC Official Full Name RNF14 pseudogene 4provided by HGNC Primary source HGNC:HGNC:54672 See related Ensembl:ENSG00000223500 AllianceGenome:HGNC:54672 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RNF150, Official Symbol RNF150provided by HGNC Official Full Name ring finger protein 150provided by HGNC Primary source HGNC:HGNC:23138 See related Ensembl:ENSG00000170153 AllianceGenome:HGNC:23138 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 9.0), adrenal (RPKM 7.4) and 21 other tissues See more Orthologs mouse all
RNF151, Official Symbol RNF151provided by HGNC Official Full Name ring finger protein 151provided by HGNC Primary source HGNC:HGNC:23235 See related Ensembl:ENSG00000179580 AllianceGenome:HGNC:23235 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 20.5) See more Orthologs mouse all
RNF152, Official Symbol RNF152provided by HGNC Official Full Name ring finger protein 152provided by HGNC Primary source HGNC:HGNC:26811 See related Ensembl:ENSG00000176641 MIM:616512; AllianceGenome:HGNC:26811 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables small GTPase binding activity and ubiquitin protein ligase activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of TORC1 signaling; and protein polyubiquitination. Located in lysosomal membrane. Is integral component of organelle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 29.4), liver (RPKM 4.9) and 13 other tissues See more Orthologs mouse all
RNF152P1, Official Symbol RNF152P1provided by HGNC Official Full Name ring finger protein 152 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49743 See related AllianceGenome:HGNC:49743 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
RNF157, Official Symbol RNF157provided by HGNC Official Full Name ring finger protein 157provided by HGNC Primary source HGNC:HGNC:29402 See related Ensembl:ENSG00000141576 AllianceGenome:HGNC:29402 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of signal transduction; positive regulation of dendrite extension; and protein autoubiquitination. Predicted to be located in cell body. Predicted to be active in early endosome; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 16.0), testis (RPKM 13.4) and 11 other tissues See more Orthologs mouse all
RNF157-AS1, Official Symbol RNF157-AS1provided by HGNC Official Full Name RNF157 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44127 See related Ensembl:ENSG00000267128 AllianceGenome:HGNC:44127 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in brain (RPKM 18.3), testis (RPKM 12.1) and 16 other tissues See more
RNF166, Official Symbol RNF166provided by HGNC Official Full Name ring finger protein 166provided by HGNC Primary source HGNC:HGNC:28856 See related Ensembl:ENSG00000158717 MIM:617178; AllianceGenome:HGNC:28856 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 13.1), spleen (RPKM 9.1) and 23 other tissues See more Orthologs mouse all
RNF167, Official Symbol RNF167provided by HGNC Official Full Name ring finger protein 167provided by HGNC Primary source HGNC:HGNC:24544 See related Ensembl:ENSG00000108523 MIM:610431; AllianceGenome:HGNC:24544 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LP2254; RING105; 5730408C10Rik Summary RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 26.0), thyroid (RPKM 24.0) and 25 other tissues See more Orthologs mouse all
RNF168, Official Symbol RNF168provided by HGNC Official Full Name ring finger protein 168provided by HGNC Primary source HGNC:HGNC:26661 See related Ensembl:ENSG00000163961 MIM:612688; AllianceGenome:HGNC:26661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIDL; hRNF168 Summary This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome. [provided by RefSeq, Sep 2011] Expression Broad expression in testis (RPKM 13.5), bone marrow (RPKM 9.5) and 24 other tissues See more Orthologs mouse all
RNF169, Official Symbol RNF169provided by HGNC Official Full Name ring finger protein 169provided by HGNC Primary source HGNC:HGNC:26961 See related Ensembl:ENSG00000166439 MIM:618650; AllianceGenome:HGNC:26961 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables K63-linked polyubiquitin modification-dependent protein binding activity and nucleosome binding activity. Involved in cellular response to DNA damage stimulus and negative regulation of double-strand break repair. Located in cytosol; nuclear lumen; and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 6.7), bone marrow (RPKM 6.4) and 25 other tissues See more Orthologs mouse all
RNF17, Official Symbol RNF17provided by HGNC Official Full Name ring finger protein 17provided by HGNC Primary source HGNC:HGNC:10060 See related Ensembl:ENSG00000132972 MIM:605793; AllianceGenome:HGNC:10060 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TDRD4; Mmip-2; SPATA23 Summary This gene is similar to a mouse gene that encodes a testis-specific protein containing a RING finger domain. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010] Expression Restricted expression toward testis (RPKM 10.4) See more Orthologs mouse all
RNF170, Official Symbol RNF170provided by HGNC Official Full Name ring finger protein 170provided by HGNC Primary source HGNC:HGNC:25358 See related Ensembl:ENSG00000120925 MIM:614649; AllianceGenome:HGNC:25358 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADSA; SNAX1; SPG85 Summary This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Expression Ubiquitous expression in thyroid (RPKM 10.8), brain (RPKM 6.2) and 24 other tissues See more Orthologs mouse all
RNF175, Official Symbol RNF175provided by HGNC Official Full Name ring finger protein 175provided by HGNC Primary source HGNC:HGNC:27735 See related Ensembl:ENSG00000145428 AllianceGenome:HGNC:27735 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in appendix (RPKM 5.6), brain (RPKM 2.9) and 18 other tissues See more Orthologs all
RNF180, Official Symbol RNF180provided by HGNC Official Full Name ring finger protein 180provided by HGNC Primary source HGNC:HGNC:27752 See related Ensembl:ENSG00000164197 MIM:616015; AllianceGenome:HGNC:27752 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RINES Summary Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in norepinephrine metabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and serotonin metabolic process. Predicted to act upstream of or within several processes, including adult behavior; positive regulation of protein ubiquitination; and protein polyubiquitination. Predicted to be located in nuclear envelope. Predicted to be integral component of membrane. Predicted to be intrinsic component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 3.9), brain (RPKM 2.6) and 23 other tissues See more Orthologs mouse all
RNF181, Official Symbol RNF181provided by HGNC Official Full Name ring finger protein 181provided by HGNC Primary source HGNC:HGNC:28037 See related Ensembl:ENSG00000168894 MIM:612490; AllianceGenome:HGNC:28037 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSPC238 Summary RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008] Expression Ubiquitous expression in kidney (RPKM 21.9), placenta (RPKM 18.7) and 25 other tissues See more Orthologs mouse all
RNF182, Official Symbol RNF182provided by HGNC Official Full Name ring finger protein 182provided by HGNC Primary source HGNC:HGNC:28522 See related Ensembl:ENSG00000180537 AllianceGenome:HGNC:28522 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 4.5), bone marrow (RPKM 2.7) and 7 other tissues See more Orthologs mouse all
RNF183, Official Symbol RNF183provided by HGNC Official Full Name ring finger protein 183provided by HGNC Primary source HGNC:HGNC:28721 See related Ensembl:ENSG00000165188 AllianceGenome:HGNC:28721 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin protein ligase activity. Involved in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; protein ubiquitination; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in gall bladder (RPKM 1.5), kidney (RPKM 1.3) and 7 other tissues See more Orthologs mouse all
RNF185, Official Symbol RNF185provided by HGNC Official Full Name ring finger protein 185provided by HGNC Primary source HGNC:HGNC:26783 See related Ensembl:ENSG00000138942 MIM:620096; AllianceGenome:HGNC:26783 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Involved in positive regulation of ERAD pathway; protein autoubiquitination; and ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 37.5), prostate (RPKM 19.7) and 25 other tissues See more Orthologs mouse all
RNF186, Official Symbol RNF186provided by HGNC Official Full Name ring finger protein 186provided by HGNC Primary source HGNC:HGNC:25978 See related Ensembl:ENSG00000178828 MIM:617163; AllianceGenome:HGNC:25978 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin-protein transferase activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
RNF187, Official Symbol RNF187provided by HGNC Official Full Name ring finger protein 187provided by HGNC Primary source HGNC:HGNC:27146 See related Ensembl:ENSG00000168159 MIM:613754; AllianceGenome:HGNC:27146 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RACO1; RACO-1 Summary Enables ubiquitin-protein transferase activity. Involved in positive regulation of transcription, DNA-templated; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 54.8), brain (RPKM 49.5) and 25 other tissues See more Orthologs mouse all
RNF19A, Official Symbol RNF19Aprovided by HGNC Official Full Name ring finger protein 19A, RBR E3 ubiquitin protein ligaseprovided by HGNC Primary source HGNC:HGNC:13432 See related Ensembl:ENSG00000034677 MIM:607119; AllianceGenome:HGNC:13432 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF19 Summary This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in testis (RPKM 28.2), gall bladder (RPKM 22.2) and 25 other tissues See more Orthologs mouse all
RNF19B, Official Symbol RNF19Bprovided by HGNC Official Full Name ring finger protein 19Bprovided by HGNC Primary source HGNC:HGNC:26886 See related Ensembl:ENSG00000116514 MIM:610872; AllianceGenome:HGNC:26886 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NKLAM; IBRDC3 Summary This gene encodes a multi-pass membrane protein containing two RING-type and one IBR-type zinc finger motifs. The encoded protin is an E3 ubiquitin-protein ligase that plays a role in the cytotoxic effects of natural killer (NK) cells. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes X and Y in a possible pseudoautosomal region. [provided by RefSeq, Jul 2014] Expression Broad expression in testis (RPKM 31.7), bone marrow (RPKM 15.6) and 23 other tissues See more Orthologs mouse all
RNF2, Official Symbol RNF2provided by HGNC Official Full Name ring finger protein 2provided by HGNC Primary source HGNC:HGNC:10061 See related Ensembl:ENSG00000121481 MIM:608985; AllianceGenome:HGNC:10061 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BAP1; DING; BAP-1; HIPI3; RING2; LUSYAM; RING1B Summary Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 7.8), placenta (RPKM 6.0) and 25 other tissues See more Orthologs mouse all
RNF20, Official Symbol RNF20provided by HGNC Official Full Name ring finger protein 20provided by HGNC Primary source HGNC:HGNC:10062 See related Ensembl:ENSG00000155827 MIM:607699; AllianceGenome:HGNC:10062 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BRE1; BRE1A; hBRE1 Summary The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in testis (RPKM 16.7), brain (RPKM 13.7) and 25 other tissues See more Orthologs mouse all
RNF207, Official Symbol RNF207provided by HGNC Official Full Name ring finger protein 207provided by HGNC Primary source HGNC:HGNC:32947 See related Ensembl:ENSG00000158286 MIM:616923; AllianceGenome:HGNC:32947 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf188 Summary Enables Hsp70 protein binding activity; chaperone binding activity; and transmembrane transporter binding activity. Involved in positive regulation of delayed rectifier potassium channel activity; positive regulation of gene expression; and positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in heart (RPKM 5.9), prostate (RPKM 3.0) and 24 other tissues See more Orthologs mouse all
RNF207-AS1, Official Symbol RNF207-AS1provided by HGNC Official Full Name RNF207 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41286 See related Ensembl:ENSG00000226944 AllianceGenome:HGNC:41286 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in kidney (RPKM 1.0), thyroid (RPKM 0.8) and 20 other tissues See more
RNF208, Official Symbol RNF208provided by HGNC Official Full Name ring finger protein 208provided by HGNC Primary source HGNC:HGNC:25420 See related Ensembl:ENSG00000212864 MIM:618993; AllianceGenome:HGNC:25420 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin-protein transferase activity. Involved in protein autoubiquitination. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
RNF212, Official Symbol RNF212provided by HGNC Official Full Name ring finger protein 212provided by HGNC Primary source HGNC:HGNC:27729 See related Ensembl:ENSG00000178222 MIM:612041; AllianceGenome:HGNC:27729 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZHP3; SPGF62 Summary This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010] Expression Broad expression in ovary (RPKM 1.7), testis (RPKM 1.5) and 20 other tissues See more Orthologs mouse all
RNF212B, Official Symbol RNF212Bprovided by HGNC Official Full Name ring finger protein 212Bprovided by HGNC Primary source HGNC:HGNC:20438 See related Ensembl:ENSG00000215277 AllianceGenome:HGNC:20438 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf164 Summary Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be active in synaptonemal complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 3.6), testis (RPKM 2.0) and 20 other tissues See more Orthologs mouse all
RNF213, Official Symbol RNF213provided by HGNC Official Full Name ring finger protein 213provided by HGNC Primary source HGNC:HGNC:14539 See related Ensembl:ENSG00000173821 MIM:613768; AllianceGenome:HGNC:14539 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALO17; MYMY2; MYSTR; NET57; C17orf27; KIAA1618 Summary This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] Expression Ubiquitous expression in spleen (RPKM 11.7), appendix (RPKM 11.6) and 25 other tissues See more Orthologs mouse all
RNF213-AS1, Official Symbol RNF213-AS1provided by HGNC Official Full Name RNF213 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:54402 See related Ensembl:ENSG00000263069 AllianceGenome:HGNC:54402 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in spleen (RPKM 2.6), appendix (RPKM 2.5) and 25 other tissues See more
RNF214, Official Symbol RNF214provided by HGNC Official Full Name ring finger protein 214provided by HGNC Primary source HGNC:HGNC:25335 See related Ensembl:ENSG00000167257 AllianceGenome:HGNC:25335 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 13.2), thyroid (RPKM 7.5) and 25 other tissues See more Orthologs mouse all
RNF215, Official Symbol RNF215provided by HGNC Official Full Name ring finger protein 215provided by HGNC Primary source HGNC:HGNC:33434 See related Ensembl:ENSG00000099999 AllianceGenome:HGNC:33434 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Golgi to vacuole transport; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be part of Golgi transport complex. Predicted to be active in endosome; membrane; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 6.2), endometrium (RPKM 5.2) and 25 other tissues See more Orthologs mouse all
RNF216, Official Symbol RNF216provided by HGNC Official Full Name ring finger protein 216provided by HGNC Primary source HGNC:HGNC:21698 See related Ensembl:ENSG00000011275 MIM:609948; AllianceGenome:HGNC:21698 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIN; CAHH; U7I1; TRIAD3; UBCE7IP1 Summary This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 16.3), lymph node (RPKM 10.2) and 25 other tissues See more Orthologs mouse all
RNF216-IT1, Official Symbol RNF216-IT1provided by HGNC Official Full Name RNF216 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41463 See related Ensembl:ENSG00000237738 AllianceGenome:HGNC:41463 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
RNF217, Official Symbol RNF217provided by HGNC Official Full Name ring finger protein 217provided by HGNC Primary source HGNC:HGNC:21487 See related Ensembl:ENSG00000146373 MIM:618592; AllianceGenome:HGNC:21487 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OSTL; IBRDC1; C6orf172; dJ84N20.1 Summary This protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] Expression Ubiquitous expression in fat (RPKM 3.1), skin (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
RNF217-AS1, Official Symbol RNF217-AS1provided by HGNC Official Full Name RNF217 antisense RNA 1 (head to head)provided by HGNC Primary source HGNC:HGNC:50866 See related Ensembl:ENSG00000236548 MIM:602532; AllianceGenome:HGNC:50866 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STL Expression Low expression observed in reference dataset See more
RNF220, Official Symbol RNF220provided by HGNC Official Full Name ring finger protein 220provided by HGNC Primary source HGNC:HGNC:25552 See related Ensembl:ENSG00000187147 MIM:616136; AllianceGenome:HGNC:25552 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLD23; C1orf164 Summary Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of canonical Wnt signaling pathway. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 10.7), testis (RPKM 7.1) and 25 other tissues See more Orthologs mouse all
RNF222, Official Symbol RNF222provided by HGNC Official Full Name ring finger protein 222provided by HGNC Primary source HGNC:HGNC:34517 See related Ensembl:ENSG00000189051 AllianceGenome:HGNC:34517 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable metal ion binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 4.4), skin (RPKM 1.4) and 1 other tissue See more Orthologs mouse all
RNF223, Official Symbol RNF223provided by HGNC Official Full Name ring finger protein 223provided by HGNC Primary source HGNC:HGNC:40020 See related Ensembl:ENSG00000237330 AllianceGenome:HGNC:40020 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable metal ion binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 1.5), stomach (RPKM 1.1) and 19 other tissues See more Orthologs mouse all
RNF224, Official Symbol RNF224provided by HGNC Official Full Name ring finger protein 224provided by HGNC Primary source HGNC:HGNC:41912 See related Ensembl:ENSG00000233198 AllianceGenome:HGNC:41912 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
RNF225, Official Symbol RNF225provided by HGNC Official Full Name ring finger protein 225provided by HGNC Primary source HGNC:HGNC:51249 See related Ensembl:ENSG00000269855 AllianceGenome:HGNC:51249 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable metal ion binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 7.7), skin (RPKM 4.9) and 1 other tissue See more Orthologs mouse all
RNF227, Official Symbol RNF227provided by HGNC Official Full Name ring finger protein 227provided by HGNC Primary source HGNC:HGNC:27571 See related Ensembl:ENSG00000179859 AllianceGenome:HGNC:27571 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LINC02581 Summary Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 21.9), ovary (RPKM 2.7) and 13 other tissues See more Orthologs mouse all
RNF24, Official Symbol RNF24provided by HGNC Official Full Name ring finger protein 24provided by HGNC Primary source HGNC:HGNC:13779 See related Ensembl:ENSG00000101236 MIM:612489; AllianceGenome:HGNC:13779 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G1L Summary This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in bone marrow (RPKM 12.4), brain (RPKM 5.0) and 23 other tissues See more Orthologs mouse all
RNF25, Official Symbol RNF25provided by HGNC Official Full Name ring finger protein 25provided by HGNC Primary source HGNC:HGNC:14662 See related Ensembl:ENSG00000163481 MIM:616014; AllianceGenome:HGNC:14662 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AO7 Summary The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 11.2), thyroid (RPKM 8.7) and 25 other tissues See more Orthologs mouse all
RNF26, Official Symbol RNF26provided by HGNC Official Full Name ring finger protein 26provided by HGNC Primary source HGNC:HGNC:14646 See related Ensembl:ENSG00000173456 MIM:606130; AllianceGenome:HGNC:14646 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008] Orthologs mouse all