psui3905/ncbi_genes_summary huggingface dataset:
CENPI, Official Symbol CENPIprovided by HGNC Official Full Name centromere protein Iprovided by HGNC Primary source HGNC:HGNC:3968 See related Ensembl:ENSG00000102384 MIM:300065; AllianceGenome:HGNC:3968 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LRPR1; CENP-I; FSHPRH1 Summary This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016] Expression Broad expression in lymph node (RPKM 1.1), appendix (RPKM 0.7) and 22 other tissues See more Orthologs mouse all
CENPJ, Official Symbol CENPJprovided by HGNC Official Full Name centromere protein Jprovided by HGNC Primary source HGNC:HGNC:17272 See related Ensembl:ENSG00000151849 MIM:609279; AllianceGenome:HGNC:17272 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAP; CPAP; LIP1; BM032; MCPH6; SASS4; SCKL4; Sas-4; CENP-J Summary This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] Expression Broad expression in testis (RPKM 7.3), thyroid (RPKM 2.9) and 22 other tissues See more Orthologs mouse all
CENPK, Official Symbol CENPKprovided by HGNC Official Full Name centromere protein Kprovided by HGNC Primary source HGNC:HGNC:29479 See related Ensembl:ENSG00000123219 MIM:611502; AllianceGenome:HGNC:29479 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P33; Solt; CENP-K; FKSG14; AF5alpha Summary CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 1.8), bone marrow (RPKM 1.7) and 19 other tissues See more Orthologs mouse all
CENPL, Official Symbol CENPLprovided by HGNC Official Full Name centromere protein Lprovided by HGNC Primary source HGNC:HGNC:17879 See related Ensembl:ENSG00000120334 MIM:611503; AllianceGenome:HGNC:17879 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENP-L; C1orf155; dJ383J4.3 Summary CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) [PubMed 16622420].[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 4.2), bone marrow (RPKM 2.4) and 22 other tissues See more Orthologs mouse all
CENPM, Official Symbol CENPMprovided by HGNC Official Full Name centromere protein Mprovided by HGNC Primary source HGNC:HGNC:18352 See related Ensembl:ENSG00000100162 MIM:610152; AllianceGenome:HGNC:18352 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PANE1; CENP-M; C22orf18 Summary The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Broad expression in bone marrow (RPKM 4.2), lymph node (RPKM 4.2) and 15 other tissues See more Orthologs mouse all
CENPN, Official Symbol CENPNprovided by HGNC Official Full Name centromere protein Nprovided by HGNC Primary source HGNC:HGNC:30873 See related Ensembl:ENSG00000166451 MIM:611509; AllianceGenome:HGNC:30873 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BM039; CENP-N; ICEN32; C16orf60 Summary The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in prostate (RPKM 4.4), bone marrow (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
CENPNP1, Official Symbol CENPNP1provided by HGNC Official Full Name CENPN pseudogene 1provided by HGNC Primary source HGNC:HGNC:54592 See related Ensembl:ENSG00000233671 AllianceGenome:HGNC:54592 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CENPO, Official Symbol CENPOprovided by HGNC Official Full Name centromere protein Oprovided by HGNC Primary source HGNC:HGNC:28152 See related Ensembl:ENSG00000138092 MIM:611504; AllianceGenome:HGNC:28152 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENP-O; MCM21R; ICEN-36 Summary This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in placenta (RPKM 11.4), testis (RPKM 8.5) and 24 other tissues See more Orthologs mouse all
CENPP, Official Symbol CENPPprovided by HGNC Official Full Name centromere protein Pprovided by HGNC Primary source HGNC:HGNC:32933 See related Ensembl:ENSG00000188312 MIM:611505; AllianceGenome:HGNC:32933 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENP-P Summary CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in skin (RPKM 7.8), esophagus (RPKM 2.2) and 24 other tissues See more Orthologs mouse all
CENPQ, Official Symbol CENPQprovided by HGNC Official Full Name centromere protein Qprovided by HGNC Primary source HGNC:HGNC:21347 See related Ensembl:ENSG00000031691 MIM:611506; AllianceGenome:HGNC:21347 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENP-Q; C6orf139 Summary CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 3.5), brain (RPKM 3.4) and 25 other tissues See more Orthologs mouse all
CENPS, Official Symbol CENPSprovided by HGNC Official Full Name centromere protein Sprovided by HGNC Primary source HGNC:HGNC:23163 See related Ensembl:ENSG00000175279 MIM:609130; AllianceGenome:HGNC:23163 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MHF1; APITD1; CENP-S; FAAP16 Summary This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2010] Expression Broad expression in testis (RPKM 21.7), kidney (RPKM 12.6) and 24 other tissues See more Orthologs mouse all
CENPS-CORT, Official Symbol CENPS-CORTprovided by HGNC Official Full Name CENPS-CORT readthroughprovided by HGNC Primary source HGNC:HGNC:38843 See related Ensembl:ENSG00000251503 AllianceGenome:HGNC:38843 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MHF1; CENPS; APITD1; CENP-S; FAAP16; APITD1-CORT Summary This locus represents naturally occurring read-through transcription between the neighboring APITD1 (apoptosis-inducing, TAF9-like domain 1) and CORT (cortistatin) genes. Alternative splicing results in multiple transcript variants, two of which encode fusion proteins that share sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2011] Expression Broad expression in testis (RPKM 17.2), kidney (RPKM 10.2) and 23 other tissues See more Orthologs all
CENPT, Official Symbol CENPTprovided by HGNC Official Full Name centromere protein Tprovided by HGNC Primary source HGNC:HGNC:25787 See related Ensembl:ENSG00000102901 MIM:611510; AllianceGenome:HGNC:25787 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSMGA; CENP-T; C16orf56 Summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in skin (RPKM 26.3), testis (RPKM 20.1) and 25 other tissues See more Orthologs mouse all
CENPU, Official Symbol CENPUprovided by HGNC Official Full Name centromere protein Uprovided by HGNC Primary source HGNC:HGNC:21348 See related Ensembl:ENSG00000151725 MIM:611511; AllianceGenome:HGNC:21348 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLIP1; PBIP1; CENP50; MLF1IP; CENPU50 Summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 44.2), bone marrow (RPKM 27.7) and 10 other tissues See more Orthologs mouse all
CENPUP2, Official Symbol CENPUP2provided by HGNC Official Full Name centromere protein U pseudogene 2provided by HGNC Primary source HGNC:HGNC:49890 See related Ensembl:ENSG00000258546 AllianceGenome:HGNC:49890 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CENPV, Official Symbol CENPVprovided by HGNC Official Full Name centromere protein Vprovided by HGNC Primary source HGNC:HGNC:29920 See related Ensembl:ENSG00000166582 MIM:608139; AllianceGenome:HGNC:29920 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p30; PRR6; CENP-V; 3110013H01Rik Summary Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. Involved in pericentric heterochromatin assembly; positive regulation of cytokinesis; and regulation of chromosome organization. Acts upstream of or within ameboidal-type cell migration. Located in several cellular components, including midbody; nucleus; and spindle midzone. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in small intestine (RPKM 17.0), duodenum (RPKM 16.5) and 25 other tissues See more Orthologs mouse all
CENPVL1, Official Symbol CENPVL1provided by HGNC Official Full Name centromere protein V like 1provided by HGNC Primary source HGNC:HGNC:31851 See related Ensembl:ENSG00000223591 AllianceGenome:HGNC:31851 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRR6L1; CENPVP1 Summary Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
CENPVL2, Official Symbol CENPVL2provided by HGNC Official Full Name centromere protein V like 2provided by HGNC Primary source HGNC:HGNC:43879 See related Ensembl:ENSG00000283093 AllianceGenome:HGNC:43879 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENPVP2 Summary Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
CENPVL3, Official Symbol CENPVL3provided by HGNC Official Full Name centromere protein V like 3provided by HGNC Primary source HGNC:HGNC:43880 See related Ensembl:ENSG00000224109 AllianceGenome:HGNC:43880 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENPVP3 Summary Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
CENPW, Official Symbol CENPWprovided by HGNC Official Full Name centromere protein Wprovided by HGNC Primary source HGNC:HGNC:21488 See related Ensembl:ENSG00000203760 MIM:611264; AllianceGenome:HGNC:21488 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CUG2; CENP-W; C6orf173 Summary Predicted to enable DNA binding activity and protein heterodimerization activity. Involved in chromosome segregation; kinetochore assembly; and mitotic cell cycle. Located in kinetochore and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 2.8), testis (RPKM 2.0) and 20 other tissues See more Orthologs mouse all
CENPX, Official Symbol CENPXprovided by HGNC Official Full Name centromere protein Xprovided by HGNC Primary source HGNC:HGNC:11422 See related Ensembl:ENSG00000169689 MIM:615128; AllianceGenome:HGNC:11422 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D9; MHF2; CENP-X; FAAP10; STRA13 Summary Enables DNA binding activity. Contributes to double-stranded DNA binding activity. Involved in replication fork processing and resolution of meiotic recombination intermediates. Part of FANCM-MHF complex and Fanconi anaemia nuclear complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 17.1), colon (RPKM 14.3) and 25 other tissues See more Orthologs mouse all
CEP104, Official Symbol CEP104provided by HGNC Official Full Name centrosomal protein 104provided by HGNC Primary source HGNC:HGNC:24866 See related Ensembl:ENSG00000116198 MIM:616690; AllianceGenome:HGNC:24866 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GlyBP; MRT77; ROC22; JBTS25; CFAP256; KIAA0562 Summary This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in testis (RPKM 6.6), kidney (RPKM 6.5) and 25 other tissues See more Orthologs mouse all
CEP112, Official Symbol CEP112provided by HGNC Official Full Name centrosomal protein 112provided by HGNC Primary source HGNC:HGNC:28514 See related Ensembl:ENSG00000154240 MIM:618980; AllianceGenome:HGNC:28514 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCDC46; MACOCO; SPGF44 Summary This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Broad expression in testis (RPKM 4.7), fat (RPKM 2.6) and 20 other tissues See more Orthologs mouse all
CEP120, Official Symbol CEP120provided by HGNC Official Full Name centrosomal protein 120provided by HGNC Primary source HGNC:HGNC:26690 See related Ensembl:ENSG00000168944 MIM:613446; AllianceGenome:HGNC:26690 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JBTS31; SRTD13; CCDC100 Summary This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in testis (RPKM 11.0), ovary (RPKM 9.1) and 25 other tissues See more Orthologs mouse all
CEP126, Official Symbol CEP126provided by HGNC Official Full Name centrosomal protein 126provided by HGNC Primary source HGNC:HGNC:29264 See related Ensembl:ENSG00000110318 MIM:614634; AllianceGenome:HGNC:29264 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA1377 Summary Involved in cilium assembly; cytoplasmic microtubule organization; and mitotic spindle organization. Located in centrosome; ciliary base; and midbody. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 8.6), ovary (RPKM 3.0) and 20 other tissues See more Orthologs mouse all
CEP128, Official Symbol CEP128provided by HGNC Official Full Name centrosomal protein 128provided by HGNC Primary source HGNC:HGNC:20359 See related Ensembl:ENSG00000100629 AllianceGenome:HGNC:20359 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf61; LEDP/132; C14orf145 Summary Involved in protein localization. Located in centriole and spindle pole. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
CEP131, Official Symbol CEP131provided by HGNC Official Full Name centrosomal protein 131provided by HGNC Primary source HGNC:HGNC:29511 See related Ensembl:ENSG00000141577 MIM:613479; AllianceGenome:HGNC:29511 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AZ1; ZA1; AZI1 Summary Enables protein homodimerization activity. Involved in several processes, including intraciliary transport involved in cilium assembly; protein localization to centrosome; and regulation of centrosome duplication. Located in several cellular components, including ciliary transition zone; intercellular bridge; and microtubule organizing center. Colocalizes with centrosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 7.3), spleen (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
CEP135, Official Symbol CEP135provided by HGNC Official Full Name centrosomal protein 135provided by HGNC Primary source HGNC:HGNC:29086 See related Ensembl:ENSG00000174799 MIM:611423; AllianceGenome:HGNC:29086 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEP4; MCPH8; KIAA0635 Summary This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012] Expression Broad expression in lymph node (RPKM 5.5), endometrium (RPKM 4.6) and 24 other tissues See more Orthologs mouse all
CEP152, Official Symbol CEP152provided by HGNC Official Full Name centrosomal protein 152provided by HGNC Primary source HGNC:HGNC:29298 See related Ensembl:ENSG00000103995 MIM:613529; AllianceGenome:HGNC:29298 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCPH4; MCPH9; SCKL5 Summary This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010] Expression Broad expression in testis (RPKM 2.6), bone marrow (RPKM 2.5) and 23 other tissues See more Orthologs mouse all
CEP162, Official Symbol CEP162provided by HGNC Official Full Name centrosomal protein 162provided by HGNC Primary source HGNC:HGNC:21107 See related Ensembl:ENSG00000135315 MIM:610201; AllianceGenome:HGNC:21107 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as QN1; C6orf84; KIAA1009 Summary Involved in cilium assembly. Located in axonemal microtubule; centriole; and centrosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 6.2), thyroid (RPKM 2.2) and 24 other tissues See more Orthologs mouse all
CEP164, Official Symbol CEP164provided by HGNC Official Full Name centrosomal protein 164provided by HGNC Primary source HGNC:HGNC:29182 See related Ensembl:ENSG00000110274 MIM:614848; AllianceGenome:HGNC:29182 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPHP15 Summary This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] Expression Broad expression in testis (RPKM 9.7), endometrium (RPKM 3.1) and 25 other tissues See more Orthologs mouse all
CEP164P1, Official Symbol CEP164P1provided by HGNC Official Full Name centrosomal protein 164 pseudogene 1provided by HGNC Primary source HGNC:HGNC:44988 See related AllianceGenome:HGNC:44988 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CEP170, Official Symbol CEP170provided by HGNC Official Full Name centrosomal protein 170provided by HGNC Primary source HGNC:HGNC:28920 See related Ensembl:ENSG00000143702 MIM:613023; AllianceGenome:HGNC:28920 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAB; FAM68A; KIAA0470 Summary The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 12.9), testis (RPKM 11.4) and 23 other tissues See more Orthologs mouse all
CEP170B, Official Symbol CEP170Bprovided by HGNC Official Full Name centrosomal protein 170Bprovided by HGNC Primary source HGNC:HGNC:20362 See related Ensembl:ENSG00000099814 MIM:620251; AllianceGenome:HGNC:20362 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM68C; CEP170R; KIAA0284 Summary Predicted to be located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in colon (RPKM 9.2), brain (RPKM 9.0) and 23 other tissues See more Orthologs mouse all
CEP19, Official Symbol CEP19provided by HGNC Official Full Name centrosomal protein 19provided by HGNC Primary source HGNC:HGNC:28209 See related Ensembl:ENSG00000174007 MIM:615586; AllianceGenome:HGNC:28209 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOSPGF; C3orf34 Summary The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2. [provided by RefSeq, Apr 2014] Expression Broad expression in testis (RPKM 6.7), brain (RPKM 1.9) and 21 other tissues See more Orthologs mouse all
CEP192, Official Symbol CEP192provided by HGNC Official Full Name centrosomal protein 192provided by HGNC Primary source HGNC:HGNC:25515 See related Ensembl:ENSG00000101639 MIM:616426; AllianceGenome:HGNC:25515 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPP1R62 Summary Enables phosphatase binding activity. Involved in centrosome-templated microtubule nucleation; mitotic spindle assembly; and protein localization to centrosome. Located in centriole; centrosome; and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.2), gall bladder (RPKM 6.1) and 25 other tissues See more Orthologs mouse all
CEP20, Official Symbol CEP20provided by HGNC Official Full Name centrosomal protein 20provided by HGNC Primary source HGNC:HGNC:26435 See related Ensembl:ENSG00000133393 MIM:617149; AllianceGenome:HGNC:26435 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FOPNL; FOR20; C16orf63; PHSECRG2 Summary Enables identical protein binding activity. Involved in cilium assembly. Located in centriolar satellite and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 17.8), esophagus (RPKM 13.1) and 25 other tissues See more Orthologs mouse all
CEP250, Official Symbol CEP250provided by HGNC Official Full Name centrosomal protein 250provided by HGNC Primary source HGNC:HGNC:1859 See related Ensembl:ENSG00000126001 MIM:609689; AllianceGenome:HGNC:1859 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEP2; CNAP1; C-NAP1; CRDHL2 Summary This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in testis (RPKM 6.5), spleen (RPKM 5.2) and 24 other tissues See more Orthologs mouse all
CEP290, Official Symbol CEP290provided by HGNC Official Full Name centrosomal protein 290provided by HGNC Primary source HGNC:HGNC:29021 See related Ensembl:ENSG00000198707 MIM:610142; AllianceGenome:HGNC:29021 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag Summary This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 5.0), thyroid (RPKM 3.8) and 25 other tissues See more Orthologs mouse all
CEP295, Official Symbol CEP295provided by HGNC Official Full Name centrosomal protein 295provided by HGNC Primary source HGNC:HGNC:29366 See related Ensembl:ENSG00000166004 MIM:617728; AllianceGenome:HGNC:29366 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA1731 Summary Enables microtubule binding activity. Involved in several processes, including centriole replication; positive regulation of protein acetylation; and regulation of centrosome duplication. Located in cytosol; microtubule cytoskeleton; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.8), lymph node (RPKM 2.0) and 25 other tissues See more Orthologs mouse all
CEP295NL, Official Symbol CEP295NLprovided by HGNC Official Full Name CEP295 N-terminal likeprovided by HGNC Primary source HGNC:HGNC:44659 See related Ensembl:ENSG00000178404 AllianceGenome:HGNC:44659 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DDC8; KIAA1731NL Summary Predicted to enable microtubule binding activity. Predicted to be involved in regulation of centriole replication. Predicted to be located in motile cilium. Predicted to be active in centriole; centrosome; and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 16.5) See more Orthologs mouse all
CEP350, Official Symbol CEP350provided by HGNC Official Full Name centrosomal protein 350provided by HGNC Primary source HGNC:HGNC:24238 See related Ensembl:ENSG00000135837 MIM:617870; AllianceGenome:HGNC:24238 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GM133; CAP350 Summary The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 13.0), lymph node (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
CEP41, Official Symbol CEP41provided by HGNC Official Full Name centrosomal protein 41provided by HGNC Primary source HGNC:HGNC:12370 See related Ensembl:ENSG00000106477 MIM:610523; AllianceGenome:HGNC:12370 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JBTS15; TSGA14 Summary This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] Expression Broad expression in testis (RPKM 5.8), salivary gland (RPKM 3.3) and 23 other tissues See more Orthologs mouse all
CEP43, Official Symbol CEP43provided by HGNC Official Full Name centrosomal protein 43provided by HGNC Primary source HGNC:HGNC:17012 See related Ensembl:ENSG00000213066 MIM:605392; AllianceGenome:HGNC:17012 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FOP; FGFR1OP Summary This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] Expression Broad expression in testis (RPKM 19.6), adrenal (RPKM 5.3) and 24 other tissues See more Orthologs mouse all
CEP44, Official Symbol CEP44provided by HGNC Official Full Name centrosomal protein 44provided by HGNC Primary source HGNC:HGNC:29356 See related Ensembl:ENSG00000164118 MIM:620217; AllianceGenome:HGNC:29356 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PS1TP3; KIAA1712 Summary Enables microtubule binding activity. Involved in centriole replication and centriole-centriole cohesion. Located in centriole; centrosome; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 3.4), endometrium (RPKM 3.1) and 25 other tissues See more Orthologs mouse all
CEP55, Official Symbol CEP55provided by HGNC Official Full Name centrosomal protein 55provided by HGNC Primary source HGNC:HGNC:1161 See related Ensembl:ENSG00000138180 MIM:610000; AllianceGenome:HGNC:1161 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT111; MARCH; URCC6; C10orf3 Summary Enables identical protein binding activity. Involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body; centriolar satellite; and plasma membrane. Implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 13.8), lymph node (RPKM 8.3) and 14 other tissues See more Orthologs mouse all
CEP57, Official Symbol CEP57provided by HGNC Official Full Name centrosomal protein 57provided by HGNC Primary source HGNC:HGNC:30794 See related Ensembl:ENSG00000166037 MIM:607951; AllianceGenome:HGNC:30794 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MVA2; PIG8; TSP57 Summary This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in testis (RPKM 11.8), gall bladder (RPKM 11.4) and 25 other tissues See more Orthologs mouse all
CEP57L1, Official Symbol CEP57L1provided by HGNC Official Full Name centrosomal protein 57 like 1provided by HGNC Primary source HGNC:HGNC:21561 See related Ensembl:ENSG00000183137 AllianceGenome:HGNC:21561 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as cep57R; C6orf182; bA487F23.2 Summary Enables identical protein binding activity. Predicted to be located in cytoplasm and microtubule. Predicted to be active in centrosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.6), brain (RPKM 1.5) and 25 other tissues See more Orthologs mouse all
CEP63, Official Symbol CEP63provided by HGNC Official Full Name centrosomal protein 63provided by HGNC Primary source HGNC:HGNC:25815 See related Ensembl:ENSG00000182923 MIM:614724; AllianceGenome:HGNC:25815 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCKL6 Summary This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 6.9), fat (RPKM 3.4) and 25 other tissues See more Orthologs mouse all