psui3905/ncbi_genes_summary huggingface dataset:
ODF1, Official Symbol ODF1provided by HGNC Official Full Name outer dense fiber of sperm tails 1provided by HGNC Primary source HGNC:HGNC:8113 See related Ensembl:ENSG00000155087 MIM:182878; AllianceGenome:HGNC:8113 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ODF; RT7; ODF2; ODFP; SODF; CT133; ODF27; ODFPG; HSPB10; ODFPGA; ODFPGB Summary The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 125.7) See more Orthologs mouse all
ODF2, Official Symbol ODF2provided by HGNC Official Full Name outer dense fiber of sperm tails 2provided by HGNC Primary source HGNC:HGNC:8114 See related Ensembl:ENSG00000136811 MIM:602015; AllianceGenome:HGNC:8114 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT134; ODF84; ODF2/1; ODF2/2 Summary The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers. [provided by RefSeq, Oct 2010] Expression Biased expression in testis (RPKM 95.4), lymph node (RPKM 8.1) and 9 other tissues See more Orthologs mouse all
ODF2-AS1, Official Symbol ODF2-AS1provided by HGNC Official Full Name ODF2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:49461 See related Ensembl:ENSG00000225951 AllianceGenome:HGNC:49461 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ODF2L, Official Symbol ODF2Lprovided by HGNC Official Full Name outer dense fiber of sperm tails 2 likeprovided by HGNC Primary source HGNC:HGNC:29225 See related Ensembl:ENSG00000122417 MIM:620130; AllianceGenome:HGNC:29225 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Involved in negative regulation of cilium assembly. Located in centriolar satellite and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 2.6), lung (RPKM 2.5) and 25 other tissues See more Orthologs mouse all
ODF4, Official Symbol ODF4provided by HGNC Official Full Name outer dense fiber of sperm tails 4provided by HGNC Primary source HGNC:HGNC:19056 See related Ensembl:ENSG00000184650 MIM:610097; AllianceGenome:HGNC:19056 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT134; CT136; OPPO1 Summary This gene encodes a protein that is localized in the outer dense fibers of the tails of mature sperm. This protein is thought to have some important role in the sperm tail. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Restricted expression toward testis (RPKM 5.1) See more Orthologs mouse all
ODR4, Official Symbol ODR4provided by HGNC Official Full Name odr-4 GPCR localization factor homologprovided by HGNC Primary source HGNC:HGNC:24299 See related Ensembl:ENSG00000157181 MIM:609335; AllianceGenome:HGNC:24299 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTG1; odr-4; C1orf27 Summary Predicted to be involved in protein localization. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 12.6), prostate (RPKM 9.5) and 25 other tissues See more Orthologs mouse all
OFD1, Official Symbol OFD1provided by HGNC Official Full Name OFD1 centriole and centriolar satellite proteinprovided by HGNC Primary source HGNC:HGNC:2567 See related Ensembl:ENSG00000046651 MIM:300170; AllianceGenome:HGNC:2567 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP23; 71-7A; SGBS2; CXorf5; JBTS10 Summary This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. [provided by RefSeq, Aug 2016] Expression Ubiquitous expression in lymph node (RPKM 12.1), thyroid (RPKM 9.1) and 25 other tissues See more Orthologs mouse all
OFD1P10Y, Official Symbol OFD1P10Yprovided by HGNC Official Full Name OFD1 pseudogene 10 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23882 See related AllianceGenome:HGNC:23882 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P10; OFDYP10; OFD1PY10
OFD1P11Y, Official Symbol OFD1P11Yprovided by HGNC Official Full Name OFD1 pseudogene 11 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23883 See related Ensembl:ENSG00000237302 AllianceGenome:HGNC:23883 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P11; OFDYP11; OFD1PY11
OFD1P13Y, Official Symbol OFD1P13Yprovided by HGNC Official Full Name OFD1 pseudogene 13 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23885 See related Ensembl:ENSG00000225287 AllianceGenome:HGNC:23885 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P13; OFDYP13; OFD1PY13
OFD1P15Y, Official Symbol OFD1P15Yprovided by HGNC Official Full Name OFD1 pseudogene 15 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23887 See related AllianceGenome:HGNC:23887 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P15; OFDYP15; OFD1PY15
OFD1P17, Official Symbol OFD1P17provided by HGNC Official Full Name OFD1 pseudogene 17provided by HGNC Primary source HGNC:HGNC:1332 See related Ensembl:ENSG00000228212 AllianceGenome:HGNC:1332 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 71-7A3; 71-7A5; C5orf1; OFD1P1
OFD1P18Y, Official Symbol OFD1P18Yprovided by HGNC Official Full Name OFD1 pseudogene 18 Y-linkedprovided by HGNC Primary source HGNC:HGNC:2589 See related AllianceGenome:HGNC:2589 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 71-7A2; CYorf1; OFD1P18; OFD1PY18
OFD1P1Y, Official Symbol OFD1P1Yprovided by HGNC Official Full Name OFD1 pseudogene 1 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23873 See related Ensembl:ENSG00000226011 AllianceGenome:HGNC:23873 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P1; OFDYP1; OFD1PY1
OFD1P2Y, Official Symbol OFD1P2Yprovided by HGNC Official Full Name OFD1 pseudogene 2 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23874 See related Ensembl:ENSG00000226611 AllianceGenome:HGNC:23874 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P2; OFDYP2; OFD1PY2
OFD1P4Y, Official Symbol OFD1P4Yprovided by HGNC Official Full Name OFD1 pseudogene 4 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23876 See related Ensembl:ENSG00000229406 AllianceGenome:HGNC:23876 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P4; OFDYP4; OFD1PY4
OFD1P5Y, Official Symbol OFD1P5Yprovided by HGNC Official Full Name OFD1 pseudogene 5 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23877 See related Ensembl:ENSG00000240438 AllianceGenome:HGNC:23877 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P5; OFDYP5; OFD1PY5
OFD1P6Y, Official Symbol OFD1P6Yprovided by HGNC Official Full Name OFD1 pseudogene 6 Y-linkedprovided by HGNC Primary source HGNC:HGNC:13657 See related Ensembl:ENSG00000242153 AllianceGenome:HGNC:13657 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P2; OFD1P6; OFDYP6; OFD1PY6
OFD1P7Y, Official Symbol OFD1P7Yprovided by HGNC Official Full Name OFD1 pseudogene 7 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23879 See related Ensembl:ENSG00000238088 AllianceGenome:HGNC:23879 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P7; OFDYP7; OFD1PY7
OFD1P8Y, Official Symbol OFD1P8Yprovided by HGNC Official Full Name OFD1 pseudogene 8 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23880 See related Ensembl:ENSG00000231159 AllianceGenome:HGNC:23880 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P8; OFDYP8; OFD1PY8
OFD1P9Y, Official Symbol OFD1P9Yprovided by HGNC Official Full Name OFD1 pseudogene 9 Y-linkedprovided by HGNC Primary source HGNC:HGNC:23881 See related Ensembl:ENSG00000230476 AllianceGenome:HGNC:23881 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD1P9; OFDYP9; OFD1PY9
OGA, Official Symbol OGAprovided by HGNC Official Full Name O-GlcNAcaseprovided by HGNC Primary source HGNC:HGNC:7056 See related Ensembl:ENSG00000198408 MIM:604039; AllianceGenome:HGNC:7056 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEA5; MGEA5; NCOAT Summary The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 42.8), lymph node (RPKM 37.2) and 25 other tissues See more Orthologs mouse all
OGDH, Official Symbol OGDHprovided by HGNC Official Full Name oxoglutarate dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:8124 See related Ensembl:ENSG00000105953 MIM:613022; AllianceGenome:HGNC:8124 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1 Summary This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] Expression Ubiquitous expression in heart (RPKM 71.3), kidney (RPKM 57.5) and 24 other tissues See more Orthologs mouse all
OGDHL, Official Symbol OGDHLprovided by HGNC Official Full Name oxoglutarate dehydrogenase Lprovided by HGNC Primary source HGNC:HGNC:25590 See related Ensembl:ENSG00000197444 MIM:617513; AllianceGenome:HGNC:25590 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YOBELN Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016] Expression Biased expression in kidney (RPKM 82.8), liver (RPKM 20.1) and 3 other tissues See more Orthologs mouse all
OGFOD1, Official Symbol OGFOD1provided by HGNC Official Full Name 2-oxoglutarate and iron dependent oxygenase domain containing 1provided by HGNC Primary source HGNC:HGNC:25585 See related Ensembl:ENSG00000087263 MIM:615857; AllianceGenome:HGNC:25585 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TPA1 Summary Enables peptidyl-proline 3-dioxygenase activity. Involved in several processes, including peptidyl-proline hydroxylation; regulation of translational termination; and stress granule assembly. Located in cytoplasmic stress granule; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 10.6), esophagus (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
OGFOD2, Official Symbol OGFOD2provided by HGNC Official Full Name 2-oxoglutarate and iron dependent oxygenase domain containing 2provided by HGNC Primary source HGNC:HGNC:25823 See related Ensembl:ENSG00000111325 AllianceGenome:HGNC:25823 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable several functions, including L-ascorbic acid binding activity; dioxygenase activity; and iron ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.6), duodenum (RPKM 4.7) and 25 other tissues See more Orthologs mouse all
OGFOD3, Official Symbol OGFOD3provided by HGNC Official Full Name 2-oxoglutarate and iron dependent oxygenase domain containing 3provided by HGNC Primary source HGNC:HGNC:26174 See related Ensembl:ENSG00000181396 AllianceGenome:HGNC:26174 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C17orf101 Summary Predicted to enable several functions, including L-ascorbic acid binding activity; dioxygenase activity; and iron ion binding activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.3), prostate (RPKM 5.0) and 25 other tissues See more Orthologs mouse all
OGFR, Official Symbol OGFRprovided by HGNC Official Full Name opioid growth factor receptorprovided by HGNC Primary source HGNC:HGNC:15768 See related Ensembl:ENSG00000060491 MIM:606459; AllianceGenome:HGNC:15768 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in spleen (RPKM 22.4), lung (RPKM 12.6) and 25 other tissues See more Orthologs mouse all
OGFRL1, Official Symbol OGFRL1provided by HGNC Official Full Name opioid growth factor receptor like 1provided by HGNC Primary source HGNC:HGNC:21378 See related Ensembl:ENSG00000119900 AllianceGenome:HGNC:21378 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ331H24.1 Summary Predicted to enable opioid growth factor receptor activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 22.5), esophagus (RPKM 15.1) and 24 other tissues See more Orthologs mouse all
OGG1, Official Symbol OGG1provided by HGNC Official Full Name 8-oxoguanine DNA glycosylaseprovided by HGNC Primary source HGNC:HGNC:8125 See related Ensembl:ENSG00000114026 MIM:601982; AllianceGenome:HGNC:8125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMMH; MUTM; OGH1; HOGG1 Summary This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] Expression Ubiquitous expression in kidney (RPKM 5.9), lymph node (RPKM 5.1) and 25 other tissues See more Orthologs mouse all
OGN, Official Symbol OGNprovided by HGNC Official Full Name osteoglycinprovided by HGNC Primary source HGNC:HGNC:8126 See related Ensembl:ENSG00000106809 MIM:602383; AllianceGenome:HGNC:8126 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OG; OIF; SLRR3A Summary This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Broad expression in gall bladder (RPKM 88.2), endometrium (RPKM 64.5) and 14 other tissues See more Orthologs mouse all
OGT, Official Symbol OGTprovided by HGNC Official Full Name O-linked N-acetylglucosamine (GlcNAc) transferaseprovided by HGNC Primary source HGNC:HGNC:8127 See related Ensembl:ENSG00000147162 MIM:300255; AllianceGenome:HGNC:8127 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OGT1; HRNT1; MRX106; XLID106; HINCUT-1; O-GLCNAC Summary This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in lymph node (RPKM 56.6), spleen (RPKM 53.1) and 25 other tissues See more Orthologs mouse all
OIP5, Official Symbol OIP5provided by HGNC Official Full Name Opa interacting protein 5provided by HGNC Primary source HGNC:HGNC:20300 See related Ensembl:ENSG00000104147 MIM:606020; AllianceGenome:HGNC:20300 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT86; MIS18B; LINT-25; MIS18beta; hMIS18beta; 5730547N13Rik Summary The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein. Expression of this gene is upregulated in several cancers, making it a putative therapeutic target. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Biased expression in testis (RPKM 12.1), bone marrow (RPKM 3.3) and 11 other tissues See more Orthologs mouse all
OIP5-AS1, Official Symbol OIP5-AS1provided by HGNC Official Full Name OIP5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43563 See related Ensembl:ENSG00000247556 AllianceGenome:HGNC:43563 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as cyrano; linc-OIP5 Summary This is a conserved gene that produces a long non-coding RNA that maintains cell proliferation in embryonic stem cells. This RNA can bind to and negatively regulate the activity of multiple cellular RNAs and microRNAs, including cyclin G associated kinase and ELAV like RNA binding protein 1. [provided by RefSeq, Dec 2017] Expression Ubiquitous expression in brain (RPKM 21.6), lymph node (RPKM 13.4) and 25 other tissues See more Orthologs mouse all
OIT3, Official Symbol OIT3provided by HGNC Official Full Name oncoprotein induced transcript 3provided by HGNC Primary source HGNC:HGNC:29953 See related Ensembl:ENSG00000138315 MIM:609330; AllianceGenome:HGNC:29953 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LZP Summary This gene was identified due to its downregulation in hepatocarcinomas. The encoded protein may be involved in liver development and function. [provided by RefSeq, Sep 2016] Expression Biased expression in liver (RPKM 29.6), small intestine (RPKM 2.8) and 3 other tissues See more Orthologs mouse all
OLA1, Official Symbol OLA1provided by HGNC Official Full Name Obg like ATPase 1provided by HGNC Primary source HGNC:HGNC:28833 See related Ensembl:ENSG00000138430 MIM:611175; AllianceGenome:HGNC:28833 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DOC45; GBP45; GTBP9; GTPBP9; PTD004 Summary This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22. [provided by RefSeq, Jun 2016] Expression Ubiquitous expression in brain (RPKM 15.5), thyroid (RPKM 14.3) and 25 other tissues See more Orthologs mouse all
OLA1P1, Official Symbol OLA1P1provided by HGNC Official Full Name OLA1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:45274 See related AllianceGenome:HGNC:45274 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
OLA1P2, Official Symbol OLA1P2provided by HGNC Official Full Name OLA1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:45277 See related Ensembl:ENSG00000213671 AllianceGenome:HGNC:45277 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
OLAH, Official Symbol OLAHprovided by HGNC Official Full Name oleoyl-ACP hydrolaseprovided by HGNC Primary source HGNC:HGNC:25625 See related Ensembl:ENSG00000152463 AllianceGenome:HGNC:25625 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TE2; SAST; AURA1; THEDC1 Summary Enables dodecanoyl-[acyl-carrier-protein] hydrolase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; and palmitoyl-[acyl-carrier-protein] hydrolase activity. Involved in medium-chain fatty acid biosynthetic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 8.6) and placenta (RPKM 2.3) See more Orthologs mouse all
OLFM1, Official Symbol OLFM1provided by HGNC Official Full Name olfactomedin 1provided by HGNC Primary source HGNC:HGNC:17187 See related Ensembl:ENSG00000130558 MIM:605366; AllianceGenome:HGNC:17187 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMY; NOE1; OlfA; NOELIN1 Summary This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 118.4), adrenal (RPKM 7.6) and 1 other tissue See more Orthologs mouse all
OLFM2, Official Symbol OLFM2provided by HGNC Official Full Name olfactomedin 2provided by HGNC Primary source HGNC:HGNC:17189 See related Ensembl:ENSG00000105088 MIM:617492; AllianceGenome:HGNC:17189 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOE2; OlfC; NOELIN2; NOELIN2_V1 Summary Involved in positive regulation of smooth muscle cell differentiation. Acts upstream of or within protein secretion. Located in cytoplasm; extracellular region; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 38.1), skin (RPKM 32.4) and 13 other tissues See more Orthologs mouse all
OLFM3, Official Symbol OLFM3provided by HGNC Official Full Name olfactomedin 3provided by HGNC Primary source HGNC:HGNC:17990 See related Ensembl:ENSG00000118733 MIM:607567; AllianceGenome:HGNC:17990 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOE3; NOELIN3; OPTIMEDIN Summary Predicted to be involved in eye photoreceptor cell development. Predicted to be located in Golgi apparatus; extracellular space; and synapse. Predicted to be part of AMPA glutamate receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 5.4) and adrenal (RPKM 0.4) See more Orthologs mouse all
OLFM4, Official Symbol OLFM4provided by HGNC Official Full Name olfactomedin 4provided by HGNC Primary source HGNC:HGNC:17190 See related Ensembl:ENSG00000102837 MIM:614061; AllianceGenome:HGNC:17190 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GC1; OLM4; OlfD; GW112; hGC-1; hOLfD; UNQ362; bA209J19.1 Summary This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011] Expression Biased expression in small intestine (RPKM 721.2), duodenum (RPKM 639.8) and 4 other tissues See more Orthologs mouse all
OLFM5P, Official Symbol OLFM5Pprovided by HGNC Official Full Name olfactomedin family member 5, pseudogeneprovided by HGNC Primary source HGNC:HGNC:51927 See related AllianceGenome:HGNC:51927 Gene type pseudo RefSeq status PREDICTED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more Orthologs mouse all
OLFML1, Official Symbol OLFML1provided by HGNC Official Full Name olfactomedin like 1provided by HGNC Primary source HGNC:HGNC:24473 See related Ensembl:ENSG00000183801 AllianceGenome:HGNC:24473 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNQ564; MVAL564 Summary Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 18.5), gall bladder (RPKM 12.2) and 22 other tissues See more Orthologs mouse all
OLFML2A, Official Symbol OLFML2Aprovided by HGNC Official Full Name olfactomedin like 2Aprovided by HGNC Primary source HGNC:HGNC:27270 See related Ensembl:ENSG00000185585 MIM:615899; AllianceGenome:HGNC:27270 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO34319 Summary Predicted to enable extracellular matrix binding activity and identical protein binding activity. Predicted to act upstream of or within extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 18.8), endometrium (RPKM 12.2) and 20 other tissues See more Orthologs mouse all
OLFML2B, Official Symbol OLFML2Bprovided by HGNC Official Full Name olfactomedin like 2Bprovided by HGNC Primary source HGNC:HGNC:24558 See related Ensembl:ENSG00000162745 AllianceGenome:HGNC:24558 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes an olfactomedin domain-containing protein. Most olfactomedin domain-containing proteins are secreted glycoproteins. [provided by RefSeq, Dec 2016] Expression Broad expression in gall bladder (RPKM 9.8), placenta (RPKM 5.9) and 16 other tissues See more Orthologs mouse all
OLFML3, Official Symbol OLFML3provided by HGNC Official Full Name olfactomedin like 3provided by HGNC Primary source HGNC:HGNC:24956 See related Ensembl:ENSG00000116774 MIM:610088; AllianceGenome:HGNC:24956 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OLF44; HNOEL-iso Summary This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Broad expression in ovary (RPKM 65.9), endometrium (RPKM 56.6) and 23 other tissues See more Orthologs mouse all
OLIG1, Official Symbol OLIG1provided by HGNC Official Full Name oligodendrocyte transcription factor 1provided by HGNC Primary source HGNC:HGNC:16983 See related Ensembl:ENSG00000184221 MIM:606385; AllianceGenome:HGNC:16983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BHLHB6; BHLHE21 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron fate commitment. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
OLIG2, Official Symbol OLIG2provided by HGNC Official Full Name oligodendrocyte transcription factor 2provided by HGNC Primary source HGNC:HGNC:9398 See related Ensembl:ENSG00000205927 MIM:606386; AllianceGenome:HGNC:9398 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19 Summary This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] Expression Restricted expression toward brain (RPKM 29.0) See more Orthologs mouse all
OLIG3, Official Symbol OLIG3provided by HGNC Official Full Name oligodendrocyte transcription factor 3provided by HGNC Primary source HGNC:HGNC:18003 See related Ensembl:ENSG00000177468 MIM:609323; AllianceGenome:HGNC:18003 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Bhlhb7; bHLHe20 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
OLMALINC, Official Symbol OLMALINCprovided by HGNC Official Full Name oligodendrocyte maturation-associated long intergenic non-coding RNAprovided by HGNC Primary source HGNC:HGNC:28060 See related Ensembl:ENSG00000235823 MIM:616240; AllianceGenome:HGNC:28060 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C10orf75; HI-LNC80; LINC00263; NCRNA00263; OLMALINCAS Expression Ubiquitous expression in brain (RPKM 10.8), ovary (RPKM 8.8) and 24 other tissues See more
OLR1, Official Symbol OLR1provided by HGNC Official Full Name oxidized low density lipoprotein receptor 1provided by HGNC Primary source HGNC:HGNC:8133 See related Ensembl:ENSG00000173391 MIM:602601; AllianceGenome:HGNC:8133 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LOX1; LOXIN; SLOX1; CLEC8A; SCARE1 Summary This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] Expression Biased expression in placenta (RPKM 50.3), lung (RPKM 32.5) and 5 other tissues See more Orthologs mouse all
OMA1, Official Symbol OMA1provided by HGNC Official Full Name OMA1 zinc metallopeptidaseprovided by HGNC Primary source HGNC:HGNC:29661 See related Ensembl:ENSG00000162600 MIM:617081; AllianceGenome:HGNC:29661 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAB1; MPRP1; MPRP-1; YKR087C; ZMPOMA1; peptidase; 2010001O09Rik Summary Enables metalloendopeptidase activity. Involved in several processes, including HRI-mediated signaling; proteolysis; and regulation of mitochondrion organization. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 9.7), prostate (RPKM 9.5) and 25 other tissues See more Orthologs mouse all
OMD, Official Symbol OMDprovided by HGNC Official Full Name osteomodulinprovided by HGNC Primary source HGNC:HGNC:8134 See related Ensembl:ENSG00000127083 MIM:618926; AllianceGenome:HGNC:8134 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OSAD; SLRR2C Summary Predicted to be involved in cell adhesion and regulation of bone mineralization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in heart (RPKM 10.0), fat (RPKM 8.3) and 20 other tissues See more Orthologs mouse all
OMG, Official Symbol OMGprovided by HGNC Official Full Name oligodendrocyte myelin glycoproteinprovided by HGNC Primary source HGNC:HGNC:8135 See related Ensembl:ENSG00000126861 MIM:164345; AllianceGenome:HGNC:8135 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OMGP Summary Predicted to enable identical protein binding activity. Predicted to be involved in neuron projection regeneration. Predicted to act upstream of or within regulation of collateral sprouting of intact axon in response to injury. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 57.3) See more Orthologs mouse all
OMP, Official Symbol OMPprovided by HGNC Official Full Name olfactory marker proteinprovided by HGNC Primary source HGNC:HGNC:8136 See related Ensembl:ENSG00000254550 MIM:164340; AllianceGenome:HGNC:8136 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008] Orthologs mouse all
ONECUT1, Official Symbol ONECUT1provided by HGNC Official Full Name one cut homeobox 1provided by HGNC Primary source HGNC:HGNC:8138 See related Ensembl:ENSG00000169856 MIM:604164; AllianceGenome:HGNC:8138 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNF6; HNF-6; HNF6A Summary This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Expression Biased expression in liver (RPKM 2.0), gall bladder (RPKM 1.7) and 2 other tissues See more Orthologs mouse all
ONECUT2, Official Symbol ONECUT2provided by HGNC Official Full Name one cut homeobox 2provided by HGNC Primary source HGNC:HGNC:8139 See related Ensembl:ENSG00000119547 MIM:604894; AllianceGenome:HGNC:8139 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OC2; OC-2 Summary This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008] Expression Biased expression in gall bladder (RPKM 4.8), duodenum (RPKM 3.7) and 2 other tissues See more Orthologs mouse all