psui3905/ncbi_genes_summary huggingface dataset:
TSPAN1, Official Symbol TSPAN1provided by HGNC Official Full Name tetraspanin 1provided by HGNC Primary source HGNC:HGNC:20657 See related Ensembl:ENSG00000117472 MIM:613170; AllianceGenome:HGNC:20657 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET1; TM4C; TM4SF Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 237.8), prostate (RPKM 118.0) and 10 other tissues See more Orthologs mouse all
TSPAN10, Official Symbol TSPAN10provided by HGNC Official Full Name tetraspanin 10provided by HGNC Primary source HGNC:HGNC:29942 See related Ensembl:ENSG00000182612 AllianceGenome:HGNC:29942 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OCSP Summary Enables enzyme binding activity. Involved in establishment of protein localization to organelle. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
TSPAN11, Official Symbol TSPAN11provided by HGNC Official Full Name tetraspanin 11provided by HGNC Primary source HGNC:HGNC:30795 See related Ensembl:ENSG00000110900 AllianceGenome:HGNC:30795 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VSSW1971 Summary Predicted to be involved in cell migration. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 4.2), gall bladder (RPKM 3.5) and 22 other tissues See more Orthologs mouse all
TSPAN12, Official Symbol TSPAN12provided by HGNC Official Full Name tetraspanin 12provided by HGNC Primary source HGNC:HGNC:21641 See related Ensembl:ENSG00000106025 MIM:613138; AllianceGenome:HGNC:21641 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EVR5; NET2; NET-2; TM4SF12 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 32.8), adrenal (RPKM 28.5) and 21 other tissues See more Orthologs mouse all
TSPAN13, Official Symbol TSPAN13provided by HGNC Official Full Name tetraspanin 13provided by HGNC Primary source HGNC:HGNC:21643 See related Ensembl:ENSG00000106537 MIM:613139; AllianceGenome:HGNC:21643 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET6; NET-6; TM4SF13 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 128.5), colon (RPKM 60.3) and 22 other tissues See more Orthologs mouse all
TSPAN14, Official Symbol TSPAN14provided by HGNC Official Full Name tetraspanin 14provided by HGNC Primary source HGNC:HGNC:23303 See related Ensembl:ENSG00000108219 AllianceGenome:HGNC:23303 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM4SF14; DC-TM4F2; tspan-14 Summary Enables enzyme binding activity. Involved in positive regulation of Notch signaling pathway; protein localization to plasma membrane; and protein maturation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 22.8), placenta (RPKM 20.4) and 25 other tissues See more Orthologs mouse all
TSPAN15, Official Symbol TSPAN15provided by HGNC Official Full Name tetraspanin 15provided by HGNC Primary source HGNC:HGNC:23298 See related Ensembl:ENSG00000099282 MIM:613140; AllianceGenome:HGNC:23298 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET7; NET-7; TM4SF15; 2700063A19Rik Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 7.7), stomach (RPKM 7.1) and 21 other tissues See more Orthologs mouse all
TSPAN16, Official Symbol TSPAN16provided by HGNC Official Full Name tetraspanin 16provided by HGNC Primary source HGNC:HGNC:30725 See related Ensembl:ENSG00000130167 MIM:617580; AllianceGenome:HGNC:30725 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM-8; TM4-B; TM4SF16 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Expression Restricted expression toward testis (RPKM 28.9) See more Orthologs all
TSPAN17, Official Symbol TSPAN17provided by HGNC Official Full Name tetraspanin 17provided by HGNC Primary source HGNC:HGNC:13594 See related Ensembl:ENSG00000048140 MIM:620446; AllianceGenome:HGNC:13594 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX23; FBXO23; TM4SF17 Summary This gene encodes a member of the transmembrane 4 superfamily. It is characterized by four tetraspanin transmembrane segments. The function of this gene has not yet been determined. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in bone marrow (RPKM 17.7), testis (RPKM 13.0) and 25 other tissues See more Orthologs mouse all
TSPAN18, Official Symbol TSPAN18provided by HGNC Official Full Name tetraspanin 18provided by HGNC Primary source HGNC:HGNC:20660 See related Ensembl:ENSG00000157570 MIM:619399; AllianceGenome:HGNC:20660 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPAN Summary Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in heart (RPKM 27.7), adrenal (RPKM 13.4) and 21 other tissues See more Orthologs mouse all
TSPAN19, Official Symbol TSPAN19provided by HGNC Official Full Name tetraspanin 19provided by HGNC Primary source HGNC:HGNC:31886 See related Ensembl:ENSG00000231738 AllianceGenome:HGNC:31886 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 1.0), lung (RPKM 1.0) and 6 other tissues See more Orthologs all
TSPAN2, Official Symbol TSPAN2provided by HGNC Official Full Name tetraspanin 2provided by HGNC Primary source HGNC:HGNC:20659 See related Ensembl:ENSG00000134198 MIM:613133; AllianceGenome:HGNC:20659 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET3; TSN2; TSPAN-2 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] Expression Broad expression in endometrium (RPKM 16.8), urinary bladder (RPKM 10.7) and 19 other tissues See more Orthologs mouse all
TSPAN3, Official Symbol TSPAN3provided by HGNC Official Full Name tetraspanin 3provided by HGNC Primary source HGNC:HGNC:17752 See related Ensembl:ENSG00000140391 MIM:613134; AllianceGenome:HGNC:17752 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM4-A; TM4SF8; TSPAN-3 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009] Expression Ubiquitous expression in fat (RPKM 113.6), colon (RPKM 109.2) and 25 other tissues See more Orthologs mouse all
TSPAN31, Official Symbol TSPAN31provided by HGNC Official Full Name tetraspanin 31provided by HGNC Primary source HGNC:HGNC:10539 See related Ensembl:ENSG00000135452 MIM:181035; AllianceGenome:HGNC:10539 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAS Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 18.9), adrenal (RPKM 13.0) and 25 other tissues See more Orthologs mouse all
TSPAN32, Official Symbol TSPAN32provided by HGNC Official Full Name tetraspanin 32provided by HGNC Primary source HGNC:HGNC:13410 See related Ensembl:ENSG00000064201 MIM:603853; AllianceGenome:HGNC:13410 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ART1; PHMX; PHEMX; TSSC6 Summary This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 10.4), spleen (RPKM 4.1) and 5 other tissues See more Orthologs mouse all
TSPAN33, Official Symbol TSPAN33provided by HGNC Official Full Name tetraspanin 33provided by HGNC Primary source HGNC:HGNC:28743 See related Ensembl:ENSG00000158457 MIM:610120; AllianceGenome:HGNC:28743 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEN; PEN.; TSPAN-33 Summary Enables enzyme binding activity. Involved in pore complex assembly; protein localization to plasma membrane; and protein maturation. Located in plasma membrane. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 45.5), lymph node (RPKM 15.7) and 20 other tissues See more Orthologs mouse all
TSPAN4, Official Symbol TSPAN4provided by HGNC Official Full Name tetraspanin 4provided by HGNC Primary source HGNC:HGNC:11859 See related Ensembl:ENSG00000214063 MIM:602644; AllianceGenome:HGNC:11859 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAG2; NAG-2; TM4SF7; TSPAN-4; TETRASPAN Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 26.0), spleen (RPKM 24.1) and 25 other tissues See more Orthologs mouse all
TSPAN5, Official Symbol TSPAN5provided by HGNC Official Full Name tetraspanin 5provided by HGNC Primary source HGNC:HGNC:17753 See related Ensembl:ENSG00000168785 MIM:613136; AllianceGenome:HGNC:17753 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET4; NET-4; TM4SF9; TSPAN-5 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 32.0), ovary (RPKM 24.8) and 18 other tissues See more Orthologs mouse all
TSPAN6, Official Symbol TSPAN6provided by HGNC Official Full Name tetraspanin 6provided by HGNC Primary source HGNC:HGNC:11858 See related Ensembl:ENSG00000000003 MIM:300191; AllianceGenome:HGNC:11858 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as T245; TM4SF6; TSPAN-6 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in colon (RPKM 15.1), ovary (RPKM 15.0) and 24 other tissues See more Orthologs mouse all
TSPAN7, Official Symbol TSPAN7provided by HGNC Official Full Name tetraspanin 7provided by HGNC Primary source HGNC:HGNC:11854 See related Ensembl:ENSG00000156298 MIM:300096; AllianceGenome:HGNC:11854 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A15; MXS1; CD231; MRX58; CCG-B7; TM4SF2; XLID58; TALLA-1; TM4SF2b; DXS1692E Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 306.6), adrenal (RPKM 70.3) and 14 other tissues See more Orthologs mouse all
TSPAN8, Official Symbol TSPAN8provided by HGNC Official Full Name tetraspanin 8provided by HGNC Primary source HGNC:HGNC:11855 See related Ensembl:ENSG00000127324 MIM:600769; AllianceGenome:HGNC:11855 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CO-029; TM4SF3 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 463.8), duodenum (RPKM 388.7) and 5 other tissues See more Orthologs mouse all
TSPAN9, Official Symbol TSPAN9provided by HGNC Official Full Name tetraspanin 9provided by HGNC Primary source HGNC:HGNC:21640 See related Ensembl:ENSG00000011105 MIM:613137; AllianceGenome:HGNC:21640 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET5; NET-5; PP1057 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009] Expression Broad expression in heart (RPKM 31.5), placenta (RPKM 20.4) and 23 other tissues See more Orthologs mouse all
TSPEAR, Official Symbol TSPEARprovided by HGNC Official Full Name thrombospondin type laminin G domain and EAR repeatsprovided by HGNC Primary source HGNC:HGNC:1268 See related Ensembl:ENSG00000175894 MIM:612920; AllianceGenome:HGNC:1268 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB98; ECTD14; STHAG10; TSP-EAR; C21orf29 Summary This gene encodes a protein that contains a N-terminal thrombospondin-type laminin G domain and several tandem arranged epilepsy-associated repeats (EARs). A mutation in this gene is the cause of autosomal recessive deafness-98. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Expression Biased expression in testis (RPKM 1.1), skin (RPKM 0.4) and 9 other tissues See more Orthologs mouse all
TSPEAR-AS1, Official Symbol TSPEAR-AS1provided by HGNC Official Full Name TSPEAR antisense RNA 1provided by HGNC Primary source HGNC:HGNC:1271 See related Ensembl:ENSG00000235890 AllianceGenome:HGNC:1271 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C21orf31 Expression Biased expression in spleen (RPKM 3.0), testis (RPKM 1.2) and 11 other tissues See more
TSPO, Official Symbol TSPOprovided by HGNC Official Full Name translocator proteinprovided by HGNC Primary source HGNC:HGNC:1158 See related Ensembl:ENSG00000100300 MIM:109610; AllianceGenome:HGNC:1158 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18; TSPO1 Summary Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012] Expression Broad expression in bone marrow (RPKM 105.6), fat (RPKM 61.4) and 20 other tissues See more Orthologs mouse all
TSPO2, Official Symbol TSPO2provided by HGNC Official Full Name translocator protein 2provided by HGNC Primary source HGNC:HGNC:21256 See related Ensembl:ENSG00000112212 MIM:619409; AllianceGenome:HGNC:21256 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BZRPL1 Summary Predicted to enable cholesterol binding activity. Involved in amino acid import across plasma membrane. Located in organelle membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in bone marrow (RPKM 6.9) and testis (RPKM 0.2) See more Orthologs mouse all
TSPOAP1, Official Symbol TSPOAP1provided by HGNC Official Full Name TSPO associated protein 1provided by HGNC Primary source HGNC:HGNC:16831 See related Ensembl:ENSG00000005379 MIM:610764; AllianceGenome:HGNC:16831 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DYT22; PRAX1; BZRAP1; PBR-IP; PRAX-1; RIMBP1; RIM-BP1 Summary Enables benzodiazepine receptor binding activity. Predicted to be involved in regulation of presynaptic cytosolic calcium ion concentration. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 13.4), bone marrow (RPKM 7.4) and 23 other tissues See more Orthologs mouse all
TSPOAP1-AS1, Official Symbol TSPOAP1-AS1provided by HGNC Official Full Name TSPOAP1, SUPT4H1 and RNF43 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44148 See related Ensembl:ENSG00000265148 AllianceGenome:HGNC:44148 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BZRAP1-AS1 Expression Ubiquitous expression in lymph node (RPKM 8.2), appendix (RPKM 7.8) and 25 other tissues See more
TSPY1, Official Symbol TSPY1provided by HGNC Official Full Name testis specific protein Y-linked 1provided by HGNC Primary source HGNC:HGNC:12381 See related Ensembl:ENSG00000258992 MIM:480100; AllianceGenome:HGNC:12381 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT78; TSPY; DYS14; pJA923 Summary The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of this gene are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Expression Restricted expression toward testis (RPKM 33.8) See more
TSPY10, Official Symbol TSPY10provided by HGNC Official Full Name testis specific protein Y-linked 10provided by HGNC Primary source HGNC:HGNC:37473 See related Ensembl:ENSG00000236424 AllianceGenome:HGNC:37473 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT78; TSPY; TSPY1; TSPY3 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in sex differentiation. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 37.7) See more
TSPY11P, Official Symbol TSPY11Pprovided by HGNC Official Full Name testis specific protein Y-linked 11, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23903 See related Ensembl:ENSG00000238235 AllianceGenome:HGNC:23903 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP1
TSPY12P, Official Symbol TSPY12Pprovided by HGNC Official Full Name testis specific protein Y-linked 12, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23904 See related Ensembl:ENSG00000236435 AllianceGenome:HGNC:23904 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP2
TSPY13P, Official Symbol TSPY13Pprovided by HGNC Official Full Name testis specific protein Y-linked 13, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23905 See related Ensembl:ENSG00000187657 AllianceGenome:HGNC:23905 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP3
TSPY14P, Official Symbol TSPY14Pprovided by HGNC Official Full Name testis specific protein Y-linked 14, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23906 See related Ensembl:ENSG00000169849 AllianceGenome:HGNC:23906 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP4
TSPY16P, Official Symbol TSPY16Pprovided by HGNC Official Full Name testis specific protein Y-linked 16, pseudogeneprovided by HGNC Primary source HGNC:HGNC:37712 See related Ensembl:ENSG00000226223 AllianceGenome:HGNC:37712 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY17P, Official Symbol TSPY17Pprovided by HGNC Official Full Name testis specific protein Y-linked 17, pseudogeneprovided by HGNC Primary source HGNC:HGNC:37713 See related Ensembl:ENSG00000232620 AllianceGenome:HGNC:37713 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY18P, Official Symbol TSPY18Pprovided by HGNC Official Full Name testis specific protein Y-linked 18, pseudogeneprovided by HGNC Primary source HGNC:HGNC:37725 See related Ensembl:ENSG00000231874 AllianceGenome:HGNC:37725 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY19P, Official Symbol TSPY19Pprovided by HGNC Official Full Name testis specific protein Y-linked 19, pseudogeneprovided by HGNC Primary source HGNC:HGNC:37998 See related Ensembl:ENSG00000234583 AllianceGenome:HGNC:37998 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY2, Official Symbol TSPY2provided by HGNC Official Full Name testis specific protein Y-linked 2provided by HGNC Primary source HGNC:HGNC:23924 See related Ensembl:ENSG00000168757 AllianceGenome:HGNC:23924 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYQ1 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 29.2) See more
TSPY23P, Official Symbol TSPY23Pprovided by HGNC Official Full Name testis specific protein Y-linked 23, pseudogeneprovided by HGNC Primary source HGNC:HGNC:38594 See related Ensembl:ENSG00000229159 AllianceGenome:HGNC:38594 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY24P, Official Symbol TSPY24Pprovided by HGNC Official Full Name testis specific protein Y-linked 24, pseudogeneprovided by HGNC Primary source HGNC:HGNC:38725 See related Ensembl:ENSG00000215601 AllianceGenome:HGNC:38725 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TSPY26P, Official Symbol TSPY26Pprovided by HGNC Official Full Name testis specific protein Y-linked 26, pseudogeneprovided by HGNC Primary source HGNC:HGNC:16256 See related Ensembl:ENSG00000235217 AllianceGenome:HGNC:16256 Gene type pseudo RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYL3; bA392M18.1 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
TSPY3, Official Symbol TSPY3provided by HGNC Official Full Name testis specific protein Y-linked 3provided by HGNC Primary source HGNC:HGNC:33876 See related Ensembl:ENSG00000228927 AllianceGenome:HGNC:33876 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT78; TSPY; TSPY1; TSPY10 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in sex differentiation. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 34.5) See more
TSPY4, Official Symbol TSPY4provided by HGNC Official Full Name testis specific protein Y-linked 4provided by HGNC Primary source HGNC:HGNC:37287 See related Ensembl:ENSG00000233803 AllianceGenome:HGNC:37287 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPY8; TSPY10 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 40.8) See more
TSPY5P, Official Symbol TSPY5Pprovided by HGNC Official Full Name testis specific protein Y-linked 5, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23907 See related AllianceGenome:HGNC:23907 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP5
TSPY6P, Official Symbol TSPY6Pprovided by HGNC Official Full Name testis specific protein Y-linked 6, pseudogeneprovided by HGNC Primary source HGNC:HGNC:34039 See related Ensembl:ENSG00000270073 AllianceGenome:HGNC:34039 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP6
TSPY7P, Official Symbol TSPY7Pprovided by HGNC Official Full Name testis specific protein Y-linked 7, pseudogeneprovided by HGNC Primary source HGNC:HGNC:34040 See related Ensembl:ENSG00000188656 AllianceGenome:HGNC:34040 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYP7
TSPY8, Official Symbol TSPY8provided by HGNC Official Full Name testis specific protein Y-linked 8provided by HGNC Primary source HGNC:HGNC:37471 See related Ensembl:ENSG00000229549 AllianceGenome:HGNC:37471 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 34.5) See more
TSPYL1, Official Symbol TSPYL1provided by HGNC Official Full Name TSPY like 1provided by HGNC Primary source HGNC:HGNC:12382 See related Ensembl:ENSG00000189241 MIM:604714; AllianceGenome:HGNC:12382 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSPYL Summary The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009] Orthologs mouse all
TSPYL2, Official Symbol TSPYL2provided by HGNC Official Full Name TSPY like 2provided by HGNC Primary source HGNC:HGNC:24358 See related Ensembl:ENSG00000184205 MIM:300564; AllianceGenome:HGNC:24358 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDA1; CTCL; NP79; TSPX; CINAP; DENTT; SE204; HRIHFB2216 Summary This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth. [provided by RefSeq, Sep 2009] Expression Broad expression in ovary (RPKM 45.2), testis (RPKM 42.8) and 24 other tissues See more Orthologs mouse all
TSPYL4, Official Symbol TSPYL4provided by HGNC Official Full Name TSPY like 4provided by HGNC Primary source HGNC:HGNC:21559 See related Ensembl:ENSG00000187189 MIM:619586; AllianceGenome:HGNC:21559 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ486I3.2 Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
TSPYL5, Official Symbol TSPYL5provided by HGNC Official Full Name TSPY like 5provided by HGNC Primary source HGNC:HGNC:29367 See related Ensembl:ENSG00000180543 MIM:614721; AllianceGenome:HGNC:29367 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation; positive regulation of protein kinase B signaling; and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
TSPYL6, Official Symbol TSPYL6provided by HGNC Official Full Name TSPY like 6provided by HGNC Primary source HGNC:HGNC:14521 See related Ensembl:ENSG00000178021 AllianceGenome:HGNC:14521 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
TSR1, Official Symbol TSR1provided by HGNC Official Full Name TSR1 ribosome maturation factorprovided by HGNC Primary source HGNC:HGNC:25542 See related Ensembl:ENSG00000167721 MIM:611214; AllianceGenome:HGNC:25542 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables RNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 12.8), esophagus (RPKM 10.6) and 25 other tissues See more Orthologs mouse all
TSR2, Official Symbol TSR2provided by HGNC Official Full Name TSR2 ribosome maturation factorprovided by HGNC Primary source HGNC:HGNC:25455 See related Ensembl:ENSG00000158526 MIM:300945; AllianceGenome:HGNC:25455 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WGG1; DBA14; DT1P1A10 Summary The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in brain (RPKM 38.9), kidney (RPKM 30.3) and 25 other tissues See more Orthologs mouse all
TSR3, Official Symbol TSR3provided by HGNC Official Full Name TSR3 ribosome maturation factorprovided by HGNC Primary source HGNC:HGNC:14175 See related Ensembl:ENSG00000007520 MIM:617058; AllianceGenome:HGNC:14175 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HsTsr3; C16orf42 Summary Enables transferase activity. Involved in enzyme-directed rRNA pseudouridine synthesis. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 23.3), kidney (RPKM 22.0) and 25 other tissues See more Orthologs mouse all
TSSC4, Official Symbol TSSC4provided by HGNC Official Full Name tumor suppressing subtransferable candidate 4provided by HGNC Primary source HGNC:HGNC:12386 See related Ensembl:ENSG00000184281 MIM:603852; AllianceGenome:HGNC:12386 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in testis (RPKM 10.6), bone marrow (RPKM 6.3) and 25 other tissues See more Orthologs mouse all
TSSK1A, Official Symbol TSSK1Aprovided by HGNC Official Full Name testis specific serine kinase 1A (pseudogene)provided by HGNC Primary source HGNC:HGNC:11400 See related AllianceGenome:HGNC:11400 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSSK1; SPOGA1; STK22A; TSSK1b; TSSK7P; TSSK1AP
TSSK1B, Official Symbol TSSK1Bprovided by HGNC Official Full Name testis specific serine kinase 1Bprovided by HGNC Primary source HGNC:HGNC:14968 See related Ensembl:ENSG00000212122 MIM:610709; AllianceGenome:HGNC:14968 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSK1; TSSK1; FKSG81; SPOGA4; STK22D Summary TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008] Orthologs mouse all