psui3905/ncbi_genes_summary huggingface dataset:
HOXA3, Official Symbol HOXA3provided by HGNC Official Full Name homeobox A3provided by HGNC Primary source HGNC:HGNC:5104 See related Ensembl:ENSG00000105997 MIM:142954; AllianceGenome:HGNC:5104 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1E Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 1.8), fat (RPKM 1.4) and 17 other tissues See more Orthologs mouse all
HOXA4, Official Symbol HOXA4provided by HGNC Official Full Name homeobox A4provided by HGNC Primary source HGNC:HGNC:5105 See related Ensembl:ENSG00000197576 MIM:142953; AllianceGenome:HGNC:5105 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1D Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 4.4), lung (RPKM 4.1) and 19 other tissues See more Orthologs mouse all
HOXA5, Official Symbol HOXA5provided by HGNC Official Full Name homeobox A5provided by HGNC Primary source HGNC:HGNC:5106 See related Ensembl:ENSG00000106004 MIM:142952; AllianceGenome:HGNC:5106 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1C; HOX1.3 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 48.1), lung (RPKM 14.3) and 8 other tissues See more Orthologs mouse all
HOXA6, Official Symbol HOXA6provided by HGNC Official Full Name homeobox A6provided by HGNC Primary source HGNC:HGNC:5107 See related Ensembl:ENSG00000106006 MIM:142951; AllianceGenome:HGNC:5107 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1B; HOX1.2 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 5.2), kidney (RPKM 2.8) and 10 other tissues See more Orthologs mouse all
HOXA7, Official Symbol HOXA7provided by HGNC Official Full Name homeobox A7provided by HGNC Primary source HGNC:HGNC:5108 See related Ensembl:ENSG00000122592 MIM:142950; AllianceGenome:HGNC:5108 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANTP; HOX1; HOX1A; HOX1.1 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 9.4), adrenal (RPKM 7.6) and 14 other tissues See more Orthologs mouse all
HOXA9, Official Symbol HOXA9provided by HGNC Official Full Name homeobox A9provided by HGNC Primary source HGNC:HGNC:5109 See related Ensembl:ENSG00000078399 MIM:142956; AllianceGenome:HGNC:5109 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; ABD-B; HOX1G; HOX1.7 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011] Expression Biased expression in kidney (RPKM 13.0), endometrium (RPKM 8.0) and 11 other tissues See more Orthologs all
HOXB-AS1, Official Symbol HOXB-AS1provided by HGNC Official Full Name HOXB cluster antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43744 See related Ensembl:ENSG00000230148 MIM:618066; AllianceGenome:HGNC:43744 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXB3OS Expression Broad expression in fat (RPKM 17.1), colon (RPKM 6.0) and 20 other tissues See more
HOXB-AS3, Official Symbol HOXB-AS3provided by HGNC Official Full Name HOXB cluster antisense RNA 3provided by HGNC Primary source HGNC:HGNC:40283 See related Ensembl:ENSG00000233101 AllianceGenome:HGNC:40283 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 9.1), colon (RPKM 5.3) and 13 other tissues See more
HOXB-AS4, Official Symbol HOXB-AS4provided by HGNC Official Full Name HOXB cluster antisense RNA 4provided by HGNC Primary source HGNC:HGNC:40285 See related Ensembl:ENSG00000242207 AllianceGenome:HGNC:40285 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HOXB1, Official Symbol HOXB1provided by HGNC Official Full Name homeobox B1provided by HGNC Primary source HGNC:HGNC:5111 See related Ensembl:ENSG00000120094 MIM:142968; AllianceGenome:HGNC:5111 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HCFP3; HOX2I; Hox-2.9 Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
HOXB13, Official Symbol HOXB13provided by HGNC Official Full Name homeobox B13provided by HGNC Primary source HGNC:HGNC:5112 See related Ensembl:ENSG00000159184 MIM:604607; AllianceGenome:HGNC:5112 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPC9; PSGD Summary This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 57.5) and colon (RPKM 27.9) See more Orthologs mouse all
HOXB2, Official Symbol HOXB2provided by HGNC Official Full Name homeobox B2provided by HGNC Primary source HGNC:HGNC:5113 See related Ensembl:ENSG00000173917 MIM:142967; AllianceGenome:HGNC:5113 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K8; HOX2; HOX2H; Hox-2.8 Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 11.3), fat (RPKM 6.5) and 19 other tissues See more Orthologs mouse all
HOXB3, Official Symbol HOXB3provided by HGNC Official Full Name homeobox B3provided by HGNC Primary source HGNC:HGNC:5114 See related Ensembl:ENSG00000120093 MIM:142966; AllianceGenome:HGNC:5114 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2G; Hox-2.7 Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 1.6), fat (RPKM 1.3) and 21 other tissues See more Orthologs mouse all
HOXB4, Official Symbol HOXB4provided by HGNC Official Full Name homeobox B4provided by HGNC Primary source HGNC:HGNC:5115 See related Ensembl:ENSG00000182742 MIM:142965; AllianceGenome:HGNC:5115 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2F; HOX-2.6 Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 4.1), lung (RPKM 2.6) and 19 other tissues See more Orthologs mouse all
HOXB5, Official Symbol HOXB5provided by HGNC Official Full Name homeobox B5provided by HGNC Primary source HGNC:HGNC:5116 See related Ensembl:ENSG00000120075 MIM:142960; AllianceGenome:HGNC:5116 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HU-1; HOX2A; Hox2.1; HHO.C10 Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 6.1), colon (RPKM 5.0) and 13 other tissues See more Orthologs mouse all
HOXB6, Official Symbol HOXB6provided by HGNC Official Full Name homeobox B6provided by HGNC Primary source HGNC:HGNC:5117 See related Ensembl:ENSG00000108511 MIM:142961; AllianceGenome:HGNC:5117 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HU-2; HOX2B; Hox-2.2 Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 11.8), colon (RPKM 5.2) and 9 other tissues See more Orthologs mouse all
HOXB7, Official Symbol HOXB7provided by HGNC Official Full Name homeobox B7provided by HGNC Primary source HGNC:HGNC:5118 See related Ensembl:ENSG00000260027 MIM:142962; AllianceGenome:HGNC:5118 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2C; HHO.C1; Hox-2.3 Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 10.0), colon (RPKM 8.7) and 15 other tissues See more Orthologs mouse all
HOXB8, Official Symbol HOXB8provided by HGNC Official Full Name homeobox B8provided by HGNC Primary source HGNC:HGNC:5119 See related Ensembl:ENSG00000120068 MIM:142963; AllianceGenome:HGNC:5119 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2D; Hox-2.4 Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 4.3), colon (RPKM 4.2) and 7 other tissues See more Orthologs mouse all
HOXB9, Official Symbol HOXB9provided by HGNC Official Full Name homeobox B9provided by HGNC Primary source HGNC:HGNC:5120 See related Ensembl:ENSG00000170689 MIM:142964; AllianceGenome:HGNC:5120 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2E; HOX-2.5 Summary This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 12.6), kidney (RPKM 7.0) and 3 other tissues See more Orthologs mouse all
HOXC-AS1, Official Symbol HOXC-AS1provided by HGNC Official Full Name HOXC cluster antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43749 See related Ensembl:ENSG00000250451 AllianceGenome:HGNC:43749 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in fat (RPKM 2.1), kidney (RPKM 0.8) and 8 other tissues See more
HOXC-AS2, Official Symbol HOXC-AS2provided by HGNC Official Full Name HOXC cluster antisense RNA 2provided by HGNC Primary source HGNC:HGNC:43750 See related Ensembl:ENSG00000250133 AllianceGenome:HGNC:43750 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 1.5), fat (RPKM 0.3) and 3 other tissues See more
HOXC-AS3, Official Symbol HOXC-AS3provided by HGNC Official Full Name HOXC cluster antisense RNA 3provided by HGNC Primary source HGNC:HGNC:43751 See related Ensembl:ENSG00000251151 AllianceGenome:HGNC:43751 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 3.4), endometrium (RPKM 0.5) and 6 other tissues See more
HOXC10, Official Symbol HOXC10provided by HGNC Official Full Name homeobox C10provided by HGNC Primary source HGNC:HGNC:5122 See related Ensembl:ENSG00000180818 MIM:605560; AllianceGenome:HGNC:5122 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3I Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 15.8), skin (RPKM 3.7) and 5 other tissues See more Orthologs mouse all
HOXC11, Official Symbol HOXC11provided by HGNC Official Full Name homeobox C11provided by HGNC Primary source HGNC:HGNC:5123 See related Ensembl:ENSG00000123388 MIM:605559; AllianceGenome:HGNC:5123 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3H Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
HOXC12, Official Symbol HOXC12provided by HGNC Official Full Name homeobox C12provided by HGNC Primary source HGNC:HGNC:5124 See related Ensembl:ENSG00000123407 MIM:142975; AllianceGenome:HGNC:5124 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; HOC3F; HOX3F Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
HOXC13, Official Symbol HOXC13provided by HGNC Official Full Name homeobox C13provided by HGNC Primary source HGNC:HGNC:5125 See related Ensembl:ENSG00000123364 MIM:142976; AllianceGenome:HGNC:5125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; ECTD9; HOX3G Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 1.8), testis (RPKM 0.2) and 1 other tissue See more Orthologs mouse all
HOXC13-AS, Official Symbol HOXC13-ASprovided by HGNC Official Full Name HOXC13 antisense RNAprovided by HGNC Primary source HGNC:HGNC:43753 See related Ensembl:ENSG00000249641 AllianceGenome:HGNC:43753 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOXC-AS5 Expression Biased expression in skin (RPKM 2.1), placenta (RPKM 0.1) and 1 other tissue See more
HOXC4, Official Symbol HOXC4provided by HGNC Official Full Name homeobox C4provided by HGNC Primary source HGNC:HGNC:5126 See related Ensembl:ENSG00000198353 MIM:142974; AllianceGenome:HGNC:5126 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; cp19; HOX3E Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 4.9), ovary (RPKM 2.4) and 16 other tissues See more Orthologs mouse all
HOXC5, Official Symbol HOXC5provided by HGNC Official Full Name homeobox C5provided by HGNC Primary source HGNC:HGNC:5127 See related Ensembl:ENSG00000172789 MIM:142973; AllianceGenome:HGNC:5127 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CP11; HOX3; HOX3D Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. [provided by RefSeq, Jul 2008] Expression Biased expression in ovary (RPKM 1.6), kidney (RPKM 1.3) and 12 other tissues See more Orthologs mouse all
HOXC6, Official Symbol HOXC6provided by HGNC Official Full Name homeobox C6provided by HGNC Primary source HGNC:HGNC:5128 See related Ensembl:ENSG00000197757 MIM:142972; AllianceGenome:HGNC:5128 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CP25; HOX3; HOX3C; HHO.C8 Summary This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008] Expression Biased expression in ovary (RPKM 7.2), adrenal (RPKM 6.2) and 11 other tissues See more Orthologs mouse all
HOXC8, Official Symbol HOXC8provided by HGNC Official Full Name homeobox C8provided by HGNC Primary source HGNC:HGNC:5129 See related Ensembl:ENSG00000037965 MIM:142970; AllianceGenome:HGNC:5129 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; HOX3A Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 3.5), adrenal (RPKM 3.0) and 9 other tissues See more Orthologs mouse all
HOXC9, Official Symbol HOXC9provided by HGNC Official Full Name homeobox C9provided by HGNC Primary source HGNC:HGNC:5130 See related Ensembl:ENSG00000180806 MIM:142971; AllianceGenome:HGNC:5130 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; HOX3B Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 2.8), fat (RPKM 2.6) and 10 other tissues See more Orthologs mouse all
HOXD1, Official Symbol HOXD1provided by HGNC Official Full Name homeobox D1provided by HGNC Primary source HGNC:HGNC:5132 See related Ensembl:ENSG00000128645 MIM:142987; AllianceGenome:HGNC:5132 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4G; Hox-4.7 Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 1.7), lung (RPKM 1.6) and 16 other tissues See more Orthologs mouse all
HOXD10, Official Symbol HOXD10provided by HGNC Official Full Name homeobox D10provided by HGNC Primary source HGNC:HGNC:5133 See related Ensembl:ENSG00000128710 MIM:142984; AllianceGenome:HGNC:5133 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4D; HOX4E; Hox-4.4 Summary This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 21.4), kidney (RPKM 9.2) and 4 other tissues See more Orthologs mouse all
HOXD11, Official Symbol HOXD11provided by HGNC Official Full Name homeobox D11provided by HGNC Primary source HGNC:HGNC:5134 See related Ensembl:ENSG00000128713 MIM:142986; AllianceGenome:HGNC:5134 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4F Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 10.2), colon (RPKM 4.5) and 2 other tissues See more Orthologs mouse all
HOXD12, Official Symbol HOXD12provided by HGNC Official Full Name homeobox D12provided by HGNC Primary source HGNC:HGNC:5135 See related Ensembl:ENSG00000170178 MIM:142988; AllianceGenome:HGNC:5135 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4H Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
HOXD13, Official Symbol HOXD13provided by HGNC Official Full Name homeobox D13provided by HGNC Primary source HGNC:HGNC:5136 See related Ensembl:ENSG00000128714 MIM:142989; AllianceGenome:HGNC:5136 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDE; SPD; BDSD; SPD1; HOX4I Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 2.7), prostate (RPKM 2.6) and 1 other tissue See more Orthologs mouse all
HOXD3, Official Symbol HOXD3provided by HGNC Official Full Name homeobox D3provided by HGNC Primary source HGNC:HGNC:5137 See related Ensembl:ENSG00000128652 MIM:142980; AllianceGenome:HGNC:5137 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX1D; HOX4A; Hox-4.1 Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 1.9), endometrium (RPKM 1.4) and 11 other tissues See more Orthologs mouse all
HOXD4, Official Symbol HOXD4provided by HGNC Official Full Name homeobox D4provided by HGNC Primary source HGNC:HGNC:5138 See related Ensembl:ENSG00000170166 MIM:142981; AllianceGenome:HGNC:5138 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4B; HHO.C13; HOX-5.1; Hox-4.2 Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 14.5), kidney (RPKM 10.9) and 13 other tissues See more Orthologs mouse all
HOXD8, Official Symbol HOXD8provided by HGNC Official Full Name homeobox D8provided by HGNC Primary source HGNC:HGNC:5139 See related Ensembl:ENSG00000175879 MIM:142985; AllianceGenome:HGNC:5139 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4E; HOX5.4 Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] Expression Biased expression in kidney (RPKM 23.0), ovary (RPKM 9.5) and 10 other tissues See more Orthologs mouse all
HOXD9, Official Symbol HOXD9provided by HGNC Official Full Name homeobox D9provided by HGNC Primary source HGNC:HGNC:5140 See related Ensembl:ENSG00000128709 MIM:142982; AllianceGenome:HGNC:5140 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4C; Hox-4.3; Hox-5.2 Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 16.0), kidney (RPKM 11.1) and 10 other tissues See more Orthologs mouse all
HP, Official Symbol HPprovided by HGNC Official Full Name haptoglobinprovided by HGNC Primary source HGNC:HGNC:5141 See related Ensembl:ENSG00000257017 MIM:140100; AllianceGenome:HGNC:5141 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BP; HPA1S; HP2ALPHA2 Summary This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] Expression Restricted expression toward liver (RPKM 13200.4) See more Orthologs mouse all
HP1BP3, Official Symbol HP1BP3provided by HGNC Official Full Name heterochromatin protein 1 binding protein 3provided by HGNC Primary source HGNC:HGNC:24973 See related Ensembl:ENSG00000127483 MIM:616072; AllianceGenome:HGNC:24973 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HP1BP74; HP1-BP74 Summary Enables DNA binding activity and nucleosome binding activity. Involved in several processes, including cellular response to hypoxia; heterochromatin organization; and regulation of nucleus size. Located in chromosome and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 36.6), endometrium (RPKM 35.9) and 25 other tissues See more Orthologs mouse all
HPAT5, Gene symbol HPAT5 Gene description human pluripotency-associated transcript 5 See related Ensembl:ENSG00000280707 MIM:616837 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HPCA, Official Symbol HPCAprovided by HGNC Official Full Name hippocalcinprovided by HGNC Primary source HGNC:HGNC:5144 See related Ensembl:ENSG00000121905 MIM:142622; AllianceGenome:HGNC:5144 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDR2; DYT2 Summary The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008] Expression Restricted expression toward brain (RPKM 57.7) See more Orthologs mouse all