psui3905/ncbi_genes_summary huggingface dataset:
NOTCH2NLR, Official Symbol NOTCH2NLRprovided by HGNC Official Full Name notch 2 N-terminal like Rprovided by HGNC Primary source HGNC:HGNC:53925 See related Ensembl:ENSG00000286106 MIM:618026; AllianceGenome:HGNC:53925 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOTCH2NLD Summary Predicted to enable calcium ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 4.4), testis (RPKM 3.5) and 25 other tissues See more
NOTCH2P1, Official Symbol NOTCH2P1provided by HGNC Official Full Name notch 2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:44253 See related Ensembl:ENSG00000226446 AllianceGenome:HGNC:44253 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
NOTCH3, Official Symbol NOTCH3provided by HGNC Official Full Name notch receptor 3provided by HGNC Primary source HGNC:HGNC:7883 See related Ensembl:ENSG00000074181 MIM:600276; AllianceGenome:HGNC:7883 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMF2; LMNS; CASIL; CADASIL; CADASIL1 Summary This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 35.4), placenta (RPKM 33.8) and 22 other tissues See more Orthologs mouse all
NOTCH4, Official Symbol NOTCH4provided by HGNC Official Full Name notch receptor 4provided by HGNC Primary source HGNC:HGNC:7884 See related Ensembl:ENSG00000204301 MIM:164951; AllianceGenome:HGNC:7884 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INT3 Summary This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] Expression Broad expression in fat (RPKM 20.5), lung (RPKM 16.6) and 21 other tissues See more Orthologs mouse all
NOTO, Official Symbol NOTOprovided by HGNC Official Full Name notochord homeoboxprovided by HGNC Primary source HGNC:HGNC:31839 See related Ensembl:ENSG00000214513 AllianceGenome:HGNC:31839 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic organ development; motile cilium assembly; and regulation of cilium assembly. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
NOTUM, Official Symbol NOTUMprovided by HGNC Official Full Name notum, palmitoleoyl-protein carboxylesteraseprovided by HGNC Primary source HGNC:HGNC:27106 See related Ensembl:ENSG00000185269 MIM:609847; AllianceGenome:HGNC:27106 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hNOTUM Summary Enables palmitoleyl hydrolase activity. Involved in negative regulation of Wnt signaling pathway and protein depalmitoleylation. Acts upstream of or within bone development and regulation of bone mineralization. Predicted to be located in endoplasmic reticulum lumen and extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward placenta (RPKM 82.6) See more Orthologs mouse all
NOVA1, Official Symbol NOVA1provided by HGNC Official Full Name NOVA alternative splicing regulator 1provided by HGNC Primary source HGNC:HGNC:7886 See related Ensembl:ENSG00000139910 MIM:602157; AllianceGenome:HGNC:7886 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Nova-1 Summary This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 10.5), fat (RPKM 4.3) and 12 other tissues See more Orthologs mouse all
NOVA2, Official Symbol NOVA2provided by HGNC Official Full Name NOVA alternative splicing regulator 2provided by HGNC Primary source HGNC:HGNC:7887 See related Ensembl:ENSG00000104967 MIM:601991; AllianceGenome:HGNC:7887 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANOVA; NOVA3; NEDASB; NOVA-2 Summary Enables sequence-specific mRNA binding activity. Involved in neuron differentiation and regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 7.5), fat (RPKM 2.1) and 10 other tissues See more Orthologs mouse all
NOX1, Official Symbol NOX1provided by HGNC Official Full Name NADPH oxidase 1provided by HGNC Primary source HGNC:HGNC:7889 See related Ensembl:ENSG00000007952 MIM:300225; AllianceGenome:HGNC:7889 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOX1; NOH1; NOH-1; GP91-2; NOH-1L Summary This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] Expression Restricted expression toward colon (RPKM 30.7) See more Orthologs mouse all
NOX3, Official Symbol NOX3provided by HGNC Official Full Name NADPH oxidase 3provided by HGNC Primary source HGNC:HGNC:7890 See related Ensembl:ENSG00000074771 MIM:607105; AllianceGenome:HGNC:7890 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOX-2; GP91-3 Summary This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all
NOX4, Official Symbol NOX4provided by HGNC Official Full Name NADPH oxidase 4provided by HGNC Primary source HGNC:HGNC:7891 See related Ensembl:ENSG00000086991 MIM:605261; AllianceGenome:HGNC:7891 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KOX; KOX-1; RENOX Summary This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009] Expression Biased expression in kidney (RPKM 23.6) and endometrium (RPKM 1.5) See more Orthologs mouse all
NOX5, Official Symbol NOX5provided by HGNC Official Full Name NADPH oxidase 5provided by HGNC Primary source HGNC:HGNC:14874 See related Ensembl:ENSG00000290203 MIM:606572; AllianceGenome:HGNC:14874 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] Expression Biased expression in spleen (RPKM 7.9), testis (RPKM 4.2) and 3 other tissues See more Orthologs all
NOXA1, Official Symbol NOXA1provided by HGNC Official Full Name NADPH oxidase activator 1provided by HGNC Primary source HGNC:HGNC:10668 See related Ensembl:ENSG00000188747 MIM:611255; AllianceGenome:HGNC:10668 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p51NOX; NY-CO-31; SDCCAG31 Summary This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Ubiquitous expression in duodenum (RPKM 4.2), stomach (RPKM 4.0) and 25 other tissues See more Orthologs mouse all
NOXO1, Official Symbol NOXO1provided by HGNC Official Full Name NADPH oxidase organizer 1provided by HGNC Primary source HGNC:HGNC:19404 See related Ensembl:ENSG00000196408 MIM:611256; AllianceGenome:HGNC:19404 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SNX28; P41NOX; P41NOXA; P41NOXB; P41NOXC; SH3PXD5 Summary This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012] Expression Broad expression in colon (RPKM 2.7), appendix (RPKM 0.9) and 14 other tissues See more Orthologs mouse all
NOXRED1, Official Symbol NOXRED1provided by HGNC Official Full Name NADP dependent oxidoreductase domain containing 1provided by HGNC Primary source HGNC:HGNC:20487 See related Ensembl:ENSG00000165555 AllianceGenome:HGNC:20487 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf148 Summary Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 2.5), thyroid (RPKM 0.4) and 15 other tissues See more Orthologs mouse all
NPAP1, Official Symbol NPAP1provided by HGNC Official Full Name nuclear pore associated protein 1provided by HGNC Primary source HGNC:HGNC:1190 See related Ensembl:ENSG00000185823 MIM:610922; AllianceGenome:HGNC:1190 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C15orf2 Summary This intronless retrogene is located in the Prader-Willi syndrome region on chromosome 15. This gene exhibits tissue-specific imprinting. Expression in adult testis and brain is biallelic, while expression in fetal brain is monoallelic and only from the paternal chromosome. The encoded protein is associated with the nuclear pore complex. [provided by RefSeq, Mar 2021] Orthologs all
NPAP1P4, Official Symbol NPAP1P4provided by HGNC Official Full Name nuclear pore associated protein 1 pseudogene 4provided by HGNC Primary source HGNC:HGNC:45021 See related Ensembl:ENSG00000236521 AllianceGenome:HGNC:45021 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
NPAP1P6, Official Symbol NPAP1P6provided by HGNC Official Full Name nuclear pore associated protein 1 pseudogene 6provided by HGNC Primary source HGNC:HGNC:45023 See related Ensembl:ENSG00000238002 AllianceGenome:HGNC:45023 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
NPAP1P7, Official Symbol NPAP1P7provided by HGNC Official Full Name nuclear pore associated protein 1 pseudogene 7provided by HGNC Primary source HGNC:HGNC:51473 See related AllianceGenome:HGNC:51473 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
NPAS1, Official Symbol NPAS1provided by HGNC Official Full Name neuronal PAS domain protein 1provided by HGNC Primary source HGNC:HGNC:7894 See related Ensembl:ENSG00000130751 MIM:603346; AllianceGenome:HGNC:7894 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOP5; PASD5; bHLHe11 Summary The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 1.1), stomach (RPKM 0.8) and 8 other tissues See more Orthologs mouse all
NPAS2, Official Symbol NPAS2provided by HGNC Official Full Name neuronal PAS domain protein 2provided by HGNC Primary source HGNC:HGNC:7895 See related Ensembl:ENSG00000170485 MIM:603347; AllianceGenome:HGNC:7895 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOP4; PASD4; bHLHe9 Summary The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 4.7), urinary bladder (RPKM 4.5) and 22 other tissues See more Orthologs mouse all
NPAS3, Official Symbol NPAS3provided by HGNC Official Full Name neuronal PAS domain protein 3provided by HGNC Primary source HGNC:HGNC:19311 See related Ensembl:ENSG00000151322 MIM:609430; AllianceGenome:HGNC:19311 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOP6; PASD6; bHLHe12 Summary This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] Expression Biased expression in brain (RPKM 3.9), endometrium (RPKM 1.3) and 4 other tissues See more Orthologs mouse all
NPAS4, Official Symbol NPAS4provided by HGNC Official Full Name neuronal PAS domain protein 4provided by HGNC Primary source HGNC:HGNC:18983 See related Ensembl:ENSG00000174576 MIM:608554; AllianceGenome:HGNC:18983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NXF; Le-PAS; PASD10; bHLHe79 Summary NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] Expression Broad expression in brain (RPKM 1.7), endometrium (RPKM 1.7) and 14 other tissues See more Orthologs mouse all
NPAT, Official Symbol NPATprovided by HGNC Official Full Name nuclear protein, coactivator of histone transcriptionprovided by HGNC Primary source HGNC:HGNC:7896 See related Ensembl:ENSG00000149308 MIM:601448; AllianceGenome:HGNC:7896 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E14; p220; E14/NPAT Summary Enables protein C-terminus binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of transcription involved in G1/S transition of mitotic cell cycle. Located in Cajal body; Gemini of coiled bodies; and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 6.0), spleen (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
NPB, Official Symbol NPBprovided by HGNC Official Full Name neuropeptide Bprovided by HGNC Primary source HGNC:HGNC:30099 See related Ensembl:ENSG00000183979 MIM:607996; AllianceGenome:HGNC:30099 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L7; PPL7; PPNPB Summary This gene encodes a member of the neuropeptide B/W family of proteins and preproprotein that is proteolytically processed to generate multiple protein products. The encoded products include neuropeptide B-23 and a C-terminally extended form, neuropeptide B-29, which are characterized by an N-terminal brominated tryptophan amino acid. Both of the encoded peptides bind with higher affinity to neuropeptide B/W (NPB/W) receptor 1 compared to the related NPB/W receptor 2. These peptides may regulate feeding, pain perception, and stress in rodents. [provided by RefSeq, Jul 2015] Expression Biased expression in kidney (RPKM 3.4), fat (RPKM 2.9) and 12 other tissues See more Orthologs mouse all
NPBWR1, Official Symbol NPBWR1provided by HGNC Official Full Name neuropeptides B and W receptor 1provided by HGNC Primary source HGNC:HGNC:4522 See related Ensembl:ENSG00000288611 MIM:600730; AllianceGenome:HGNC:4522 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR7 Summary Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
NPBWR2, Official Symbol NPBWR2provided by HGNC Official Full Name neuropeptides B and W receptor 2provided by HGNC Primary source HGNC:HGNC:4530 See related Ensembl:ENSG00000125522 MIM:600731; AllianceGenome:HGNC:4530 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR8 Summary The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008] Orthologs mouse all
NPC1, Official Symbol NPC1provided by HGNC Official Full Name NPC intracellular cholesterol transporter 1provided by HGNC Primary source HGNC:HGNC:7897 See related Ensembl:ENSG00000141458 MIM:607623; AllianceGenome:HGNC:7897 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPC; POGZ; SLC65A1 Summary This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009] Expression Ubiquitous expression in adrenal (RPKM 13.9), brain (RPKM 10.0) and 24 other tissues See more Orthologs mouse all
NPC1L1, Official Symbol NPC1L1provided by HGNC Official Full Name NPC1 like intracellular cholesterol transporter 1provided by HGNC Primary source HGNC:HGNC:7898 See related Ensembl:ENSG00000015520 MIM:608010; AllianceGenome:HGNC:7898 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LDLCQ7; NPC11L1; SLC65A2 Summary The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up free cholesterol into cells through vesicular endocytosis and plays a critical role in the absorption of intestinal cholesterol. It also has the ability to transport alpha-tocopherol (vitamin E). The drug ezetimibe targets this protein and inhibits the absorption of intestinal cholesterol and alpha-tocopherol. In addition, this protein may play a critical role in regulating lipid metabolism. Polymorphic variations in this gene are associated with plasma total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) risk. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Expression Biased expression in duodenum (RPKM 24.2), small intestine (RPKM 22.9) and 2 other tissues See more Orthologs mouse all
NPC2, Official Symbol NPC2provided by HGNC Official Full Name NPC intracellular cholesterol transporter 2provided by HGNC Primary source HGNC:HGNC:14537 See related Ensembl:ENSG00000119655 MIM:601015; AllianceGenome:HGNC:14537 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HE1; EDDM1 Summary This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lung (RPKM 202.8), thyroid (RPKM 113.6) and 25 other tissues See more Orthologs mouse all
NPDC1, Official Symbol NPDC1provided by HGNC Official Full Name neural proliferation, differentiation and control 1provided by HGNC Primary source HGNC:HGNC:7899 See related Ensembl:ENSG00000107281 MIM:605798; AllianceGenome:HGNC:7899 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAB; CAB-; CAB1; CAB-1; NPDC-1 Summary Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in prostate (RPKM 64.4), stomach (RPKM 34.1) and 22 other tissues See more Orthologs mouse all
NPEPL1, Official Symbol NPEPL1provided by HGNC Official Full Name aminopeptidase like 1provided by HGNC Primary source HGNC:HGNC:16244 See related Ensembl:ENSG00000215440 AllianceGenome:HGNC:16244 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as bA261P9.2 Summary Predicted to enable manganese ion binding activity and metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 17.5), spleen (RPKM 15.8) and 25 other tissues See more Orthologs mouse all
NPEPPS, Official Symbol NPEPPSprovided by HGNC Official Full Name aminopeptidase puromycin sensitiveprovided by HGNC Primary source HGNC:HGNC:7900 See related Ensembl:ENSG00000141279 MIM:606793; AllianceGenome:HGNC:7900 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSA; AAP-S; MP100 Summary This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 43.2), brain (RPKM 28.6) and 25 other tissues See more Orthologs mouse all
NPFF, Official Symbol NPFFprovided by HGNC Official Full Name neuropeptide FF-amide peptide precursorprovided by HGNC Primary source HGNC:HGNC:7901 See related Ensembl:ENSG00000139574 MIM:604643; AllianceGenome:HGNC:7901 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FMRFAL Summary This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in skin (RPKM 3.8), spleen (RPKM 2.1) and 24 other tissues See more Orthologs mouse all
NPFFR1, Official Symbol NPFFR1provided by HGNC Official Full Name neuropeptide FF receptor 1provided by HGNC Primary source HGNC:HGNC:17425 See related Ensembl:ENSG00000148734 MIM:607448; AllianceGenome:HGNC:17425 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPFF1; GPR147; NPFF1R1; OT7T022 Summary Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
NPFFR2, Official Symbol NPFFR2provided by HGNC Official Full Name neuropeptide FF receptor 2provided by HGNC Primary source HGNC:HGNC:4525 See related Ensembl:ENSG00000056291 MIM:607449; AllianceGenome:HGNC:4525 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR74; NPFF2; NPGPR; HLWAR77 Summary This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] Expression Biased expression in placenta (RPKM 1.4), thyroid (RPKM 0.2) and 7 other tissues See more Orthologs mouse all
NPHP1, Official Symbol NPHP1provided by HGNC Official Full Name nephrocystin 1provided by HGNC Primary source HGNC:HGNC:7905 See related Ensembl:ENSG00000144061 MIM:607100; AllianceGenome:HGNC:7905 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPH1; JBTS4; SLSN1 Summary This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 11.1), thyroid (RPKM 3.0) and 12 other tissues See more Orthologs mouse all
NPHP3, Official Symbol NPHP3provided by HGNC Official Full Name nephrocystin 3provided by HGNC Primary source HGNC:HGNC:7907 See related Ensembl:ENSG00000113971 MIM:608002; AllianceGenome:HGNC:7907 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKS7; NPH3; RHPD; RHPD1; SLSN3; CFAP31 Summary This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in ovary (RPKM 12.5), endometrium (RPKM 10.4) and 25 other tissues See more Orthologs mouse all
NPHP3-ACAD11, Official Symbol NPHP3-ACAD11provided by HGNC Official Full Name NPHP3-ACAD11 readthrough (NMD candidate)provided by HGNC Primary source HGNC:HGNC:48351 See related Ensembl:ENSG00000274810 AllianceGenome:HGNC:48351 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPHP3 Summary This locus represents naturally occurring read-through transcription between the neighboring NPHP3 (nephronophthisis 3, adolescent) and ACAD11 (acyl-CoA dehydrogenase family, member 11) genes on chromosome 3. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in kidney (RPKM 14.0), liver (RPKM 13.3) and 25 other tissues See more
NPHP3-AS1, Official Symbol NPHP3-AS1provided by HGNC Official Full Name NPHP3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:24129 See related Ensembl:ENSG00000248724 AllianceGenome:HGNC:24129 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00119 Expression Low expression observed in reference dataset See more
NPHP4, Official Symbol NPHP4provided by HGNC Official Full Name nephrocystin 4provided by HGNC Primary source HGNC:HGNC:19104 See related Ensembl:ENSG00000131697 MIM:607215; AllianceGenome:HGNC:19104 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as POC10; SLSN4 Summary This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] Expression Broad expression in testis (RPKM 3.4), thyroid (RPKM 2.6) and 25 other tissues See more Orthologs mouse all
NPHS1, Official Symbol NPHS1provided by HGNC Official Full Name NPHS1 adhesion molecule, nephrinprovided by HGNC Primary source HGNC:HGNC:7908 See related Ensembl:ENSG00000161270 MIM:602716; AllianceGenome:HGNC:7908 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNF; NPHN; nephrin Summary This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009] Expression Biased expression in kidney (RPKM 12.8), pancreas (RPKM 3.0) and 1 other tissue See more Orthologs mouse all
NPHS2, Official Symbol NPHS2provided by HGNC Official Full Name NPHS2 stomatin family member, podocinprovided by HGNC Primary source HGNC:HGNC:13394 See related Ensembl:ENSG00000116218 MIM:604766; AllianceGenome:HGNC:13394 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PDCN; SRN1 Summary This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Restricted expression toward kidney (RPKM 45.3) See more Orthologs mouse all
NPIPA1, Official Symbol NPIPA1provided by HGNC Official Full Name nuclear pore complex interacting protein family member A1provided by HGNC Primary source HGNC:HGNC:7909 See related Ensembl:ENSG00000183426 MIM:606406; AllianceGenome:HGNC:7909 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIP; NPIPA; morpheus Summary Predicted to be involved in mRNA transport and protein transport. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 56.3), ovary (RPKM 53.3) and 25 other tissues See more
NPIPA2, Official Symbol NPIPA2provided by HGNC Official Full Name nuclear pore complex interacting protein family member A2provided by HGNC Primary source HGNC:HGNC:41979 See related Ensembl:ENSG00000254852 AllianceGenome:HGNC:41979 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIP; NPIPA1 Summary Predicted to be involved in mRNA transport and protein transport. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 20.2), testis (RPKM 15.4) and 25 other tissues See more
NPIPA3, Official Symbol NPIPA3provided by HGNC Official Full Name nuclear pore complex interacting protein family member A3provided by HGNC Primary source HGNC:HGNC:41978 See related Ensembl:ENSG00000224712 AllianceGenome:HGNC:41978 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 19.5), testis (RPKM 14.9) and 25 other tissues See more Orthologs all
NPIPA5, Official Symbol NPIPA5provided by HGNC Official Full Name nuclear pore complex interacting protein family member A5provided by HGNC Primary source HGNC:HGNC:41980 See related Ensembl:ENSG00000183793 AllianceGenome:HGNC:41980 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIP Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 40.1), ovary (RPKM 32.3) and 25 other tissues See more Orthologs all
NPIPA7, Official Symbol NPIPA7provided by HGNC Official Full Name nuclear pore complex interacting protein family member A7provided by HGNC Primary source HGNC:HGNC:41982 See related Ensembl:ENSG00000214967 AllianceGenome:HGNC:41982 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIPA8 Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 37.5), ovary (RPKM 28.3) and 25 other tissues See more
NPIPA8, Official Symbol NPIPA8provided by HGNC Official Full Name nuclear pore complex interacting protein family member A8provided by HGNC Primary source HGNC:HGNC:41983 See related Ensembl:ENSG00000214940 AllianceGenome:HGNC:41983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIPA7; LCR16a9 Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 33.2), ovary (RPKM 24.8) and 25 other tissues See more
NPIPA9, Official Symbol NPIPA9provided by HGNC Official Full Name nuclear pore complex interacting protein family, member A9provided by HGNC Primary source HGNC:HGNC:41984 See related Ensembl:ENSG00000233024 AllianceGenome:HGNC:41984 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 65.4), ovary (RPKM 63.0) and 25 other tissues See more
NPIPB11, Official Symbol NPIPB11provided by HGNC Official Full Name nuclear pore complex interacting protein family member B11provided by HGNC Primary source HGNC:HGNC:37453 See related Ensembl:ENSG00000254206 AllianceGenome:HGNC:37453 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPIP Summary Predicted to act upstream of or within prevention of polyspermy. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 25.8), bone marrow (RPKM 16.9) and 24 other tissues See more Orthologs all
NPIPB12, Official Symbol NPIPB12provided by HGNC Official Full Name nuclear pore complex interacting protein family member B12provided by HGNC Primary source HGNC:HGNC:37491 See related Ensembl:ENSG00000169203 AllianceGenome:HGNC:37491 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
NPIPB13, Official Symbol NPIPB13provided by HGNC Official Full Name nuclear pore complex interacting protein family, member B13provided by HGNC Primary source HGNC:HGNC:41989 See related Ensembl:ENSG00000198064 AllianceGenome:HGNC:41989 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 20.3), bone marrow (RPKM 13.4) and 24 other tissues See more