psui3905/ncbi_genes_summary huggingface dataset:
SLC25A11, Official Symbol SLC25A11provided by HGNC Official Full Name solute carrier family 25 member 11provided by HGNC Primary source HGNC:HGNC:10981 See related Ensembl:ENSG00000108528 MIM:604165; AllianceGenome:HGNC:10981 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OGC; PGL6; SLC20A4 Summary The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011] Expression Ubiquitous expression in heart (RPKM 61.1), kidney (RPKM 32.4) and 24 other tissues See more Orthologs mouse all
SLC25A12, Official Symbol SLC25A12provided by HGNC Official Full Name solute carrier family 25 member 12provided by HGNC Primary source HGNC:HGNC:10982 See related Ensembl:ENSG00000115840 MIM:603667; AllianceGenome:HGNC:10982 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AGC1; DEE39; ARALAR; EIEE39 Summary This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012] Expression Ubiquitous expression in heart (RPKM 23.7), brain (RPKM 13.5) and 23 other tissues See more Orthologs mouse all
SLC25A13, Official Symbol SLC25A13provided by HGNC Official Full Name solute carrier family 25 member 13provided by HGNC Primary source HGNC:HGNC:10983 See related Ensembl:ENSG00000004864 MIM:603859; AllianceGenome:HGNC:10983 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTLN2; NICCD; CITRIN; ARALAR2 Summary This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Expression Ubiquitous expression in liver (RPKM 31.0), kidney (RPKM 12.7) and 23 other tissues See more Orthologs mouse all
SLC25A14, Official Symbol SLC25A14provided by HGNC Official Full Name solute carrier family 25 member 14provided by HGNC Primary source HGNC:HGNC:10984 See related Ensembl:ENSG00000102078 MIM:300242; AllianceGenome:HGNC:10984 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UCP5; BMCP1 Summary Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in brain (RPKM 4.0), testis (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
SLC25A14P1, Official Symbol SLC25A14P1provided by HGNC Official Full Name solute carrier family 25 member 14 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43856 See related AllianceGenome:HGNC:43856 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A15, Official Symbol SLC25A15provided by HGNC Official Full Name solute carrier family 25 member 15provided by HGNC Primary source HGNC:HGNC:10985 See related Ensembl:ENSG00000102743 MIM:603861; AllianceGenome:HGNC:10985 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HHH; ORC1; ORNT1; LNC-HC; D13S327 Summary This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.[provided by RefSeq, May 2009] Expression Broad expression in liver (RPKM 22.5), duodenum (RPKM 18.6) and 18 other tissues See more Orthologs mouse all
SLC25A16, Official Symbol SLC25A16provided by HGNC Official Full Name solute carrier family 25 member 16provided by HGNC Primary source HGNC:HGNC:10986 See related Ensembl:ENSG00000122912 MIM:139080; AllianceGenome:HGNC:10986 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GDA; GDC; ML7; hGP; hML7; HGT.1; D10S105E Summary This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 11.2), prostate (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
SLC25A17, Official Symbol SLC25A17provided by HGNC Official Full Name solute carrier family 25 member 17provided by HGNC Primary source HGNC:HGNC:10987 See related Ensembl:ENSG00000100372 MIM:606795; AllianceGenome:HGNC:10987 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PMP34 Summary This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in ovary (RPKM 10.5), thyroid (RPKM 8.4) and 25 other tissues See more Orthologs mouse all
SLC25A18, Official Symbol SLC25A18provided by HGNC Official Full Name solute carrier family 25 member 18provided by HGNC Primary source HGNC:HGNC:10988 See related Ensembl:ENSG00000182902 MIM:609303; AllianceGenome:HGNC:10988 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GC2 Summary Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 15.7), liver (RPKM 8.1) and 2 other tissues See more Orthologs mouse all
SLC25A18P1, Official Symbol SLC25A18P1provided by HGNC Official Full Name solute carrier family 25 member 18 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43857 See related Ensembl:ENSG00000234309 AllianceGenome:HGNC:43857 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A19, Official Symbol SLC25A19provided by HGNC Official Full Name solute carrier family 25 member 19provided by HGNC Primary source HGNC:HGNC:14409 See related Ensembl:ENSG00000125454 MIM:606521; AllianceGenome:HGNC:14409 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DNC; TPC; MUP1; MCPHA; MTPPT; THMD3; THMD4 Summary This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 8.3), lymph node (RPKM 4.5) and 24 other tissues See more Orthologs mouse all
SLC25A1P2, Official Symbol SLC25A1P2provided by HGNC Official Full Name solute carrier family 25 member 1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:43847 See related AllianceGenome:HGNC:43847 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A1P3, Official Symbol SLC25A1P3provided by HGNC Official Full Name solute carrier family 25 member 1 pseudogene 3provided by HGNC Primary source HGNC:HGNC:43846 See related AllianceGenome:HGNC:43846 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A1P5, Official Symbol SLC25A1P5provided by HGNC Official Full Name solute carrier family 25 member 1 pseudogene 5provided by HGNC Primary source HGNC:HGNC:43849 See related Ensembl:ENSG00000267323 AllianceGenome:HGNC:43849 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A2, Official Symbol SLC25A2provided by HGNC Official Full Name solute carrier family 25 member 2provided by HGNC Primary source HGNC:HGNC:22921 See related Ensembl:ENSG00000120329 MIM:608157; AllianceGenome:HGNC:22921 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ORC2; ORNT2 Summary This intronless gene encodes a protein that localizes to the mitochondrial inner membrane and likely functions as a transporter of small molecules such as ornithine. This gene is located between the protocadherin beta and gamma gene clusters on chromosome 5. [provided by RefSeq, Dec 2014] Orthologs all
SLC25A20, Official Symbol SLC25A20provided by HGNC Official Full Name solute carrier family 25 member 20provided by HGNC Primary source HGNC:HGNC:1421 See related Ensembl:ENSG00000178537 MIM:613698; AllianceGenome:HGNC:1421 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAC; CACT Summary This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in liver (RPKM 37.3), duodenum (RPKM 32.0) and 25 other tissues See more Orthologs mouse all
SLC25A21, Official Symbol SLC25A21provided by HGNC Official Full Name solute carrier family 25 member 21provided by HGNC Primary source HGNC:HGNC:14411 See related Ensembl:ENSG00000183032 MIM:607571; AllianceGenome:HGNC:14411 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ODC; ODC1; MTDPS18 Summary SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004] Expression Biased expression in esophagus (RPKM 5.4), salivary gland (RPKM 2.6) and 13 other tissues See more Orthologs mouse all
SLC25A21-AS1, Official Symbol SLC25A21-AS1provided by HGNC Official Full Name SLC25A21 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44298 See related Ensembl:ENSG00000258708 AllianceGenome:HGNC:44298 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A22, Official Symbol SLC25A22provided by HGNC Official Full Name solute carrier family 25 member 22provided by HGNC Primary source HGNC:HGNC:19954 See related Ensembl:ENSG00000177542 MIM:609302; AllianceGenome:HGNC:19954 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GC1; DEE3; GC-1; EIEE3; NET44 Summary This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jul 2010] Expression Ubiquitous expression in brain (RPKM 22.0), testis (RPKM 5.8) and 24 other tissues See more Orthologs mouse all
SLC25A23, Official Symbol SLC25A23provided by HGNC Official Full Name solute carrier family 25 member 23provided by HGNC Primary source HGNC:HGNC:19375 See related Ensembl:ENSG00000125648 MIM:608746; AllianceGenome:HGNC:19375 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APC2; MCSC2; SCAMC3; SCaMC-3 Summary Predicted to enable ATP transmembrane transporter activity. Involved in calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 40.2), thyroid (RPKM 28.7) and 23 other tissues See more Orthologs mouse all
SLC25A24, Official Symbol SLC25A24provided by HGNC Official Full Name solute carrier family 25 member 24provided by HGNC Primary source HGNC:HGNC:20662 See related Ensembl:ENSG00000085491 MIM:608744; AllianceGenome:HGNC:20662 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APC1; SCAMC1; SCAMC-1 Summary This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] Expression Ubiquitous expression in small intestine (RPKM 21.4), colon (RPKM 20.9) and 25 other tissues See more Orthologs all
SLC25A24P2, Official Symbol SLC25A24P2provided by HGNC Official Full Name SLC25A24 pseudogene 2provided by HGNC Primary source HGNC:HGNC:48934 See related Ensembl:ENSG00000238118 AllianceGenome:HGNC:48934 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A25, Official Symbol SLC25A25provided by HGNC Official Full Name solute carrier family 25 member 25provided by HGNC Primary source HGNC:HGNC:20663 See related Ensembl:ENSG00000148339 MIM:608745; AllianceGenome:HGNC:20663 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCSC; PCSCL; SCAMC2; SCAMC-2 Summary The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in liver (RPKM 17.5), gall bladder (RPKM 17.0) and 25 other tissues See more Orthologs mouse all
SLC25A26, Official Symbol SLC25A26provided by HGNC Official Full Name solute carrier family 25 member 26provided by HGNC Primary source HGNC:HGNC:20661 See related Ensembl:ENSG00000144741 MIM:611037; AllianceGenome:HGNC:20661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAMC; COXPD28 Summary This gene is a member of the mitochondrial carrier family which includes nuclear-encoded transporters localized on the inner mitochondrial membranes. Members of the family transport important small molecules across the mitochondrial inner membrane. This protein is involved in the transport of S-adenosylmethionine (SAM) into the mitochondria. Mutations in this gene are associated with combined oxidative phosphorylation deficiency 28. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in brain (RPKM 11.7), fat (RPKM 7.0) and 25 other tissues See more Orthologs mouse all
SLC25A27, Official Symbol SLC25A27provided by HGNC Official Full Name solute carrier family 25 member 27provided by HGNC Primary source HGNC:HGNC:21065 See related Ensembl:ENSG00000153291 MIM:613725; AllianceGenome:HGNC:21065 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UCP4 Summary Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011] Expression Broad expression in brain (RPKM 13.5), ovary (RPKM 8.8) and 22 other tissues See more Orthologs mouse all
SLC25A28, Official Symbol SLC25A28provided by HGNC Official Full Name solute carrier family 25 member 28provided by HGNC Primary source HGNC:HGNC:23472 See related Ensembl:ENSG00000155287 MIM:609767; AllianceGenome:HGNC:23472 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MFRN2; MRS4L; MRS3/4; NPD016 Summary Predicted to enable ferrous iron transmembrane transporter activity. Predicted to be involved in iron import into the mitochondrion. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 11.6), testis (RPKM 11.1) and 25 other tissues See more Orthologs mouse all
SLC25A29, Official Symbol SLC25A29provided by HGNC Official Full Name solute carrier family 25 member 29provided by HGNC Primary source HGNC:HGNC:20116 See related Ensembl:ENSG00000197119 MIM:615064; AllianceGenome:HGNC:20116 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CACL; ORNT3; C14orf69 Summary This gene encodes a nuclear-encoded mitochondrial protein that is a member of the large family of solute carrier family 25 (SLC25) mitochondrial transporters. The members of this superfamily are involved in numerous metabolic pathways and cell functions. This gene product was previously reported to be a mitochondrial carnitine-acylcarnitine-like (CACL) translocase (PMID:128829710) or an ornithine transporter (designated ORNT3, PMID:19287344), however, a recent study characterized the main role of this protein as a mitochondrial transporter of basic amino acids, with a preference for arginine and lysine (PMID:24652292). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014] Expression Broad expression in thyroid (RPKM 41.5), prostate (RPKM 9.2) and 23 other tissues See more Orthologs mouse all
SLC25A3, Official Symbol SLC25A3provided by HGNC Official Full Name solute carrier family 25 member 3provided by HGNC Primary source HGNC:HGNC:10989 See related Ensembl:ENSG00000075415 MIM:600370; AllianceGenome:HGNC:10989 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHC; PTP; PiC; OK/SW-cl.48 Summary The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 179.1), kidney (RPKM 125.7) and 25 other tissues See more Orthologs mouse all
SLC25A30, Official Symbol SLC25A30provided by HGNC Official Full Name solute carrier family 25 member 30provided by HGNC Primary source HGNC:HGNC:27371 See related Ensembl:ENSG00000174032 MIM:610793; AllianceGenome:HGNC:27371 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KMCP1 Summary Although the outer mitochondrial membrane is permeable to many small metabolites, transport of solutes across the inner mitochondrial membrane is achieved by members of the mitochondrial carrier protein family, such as SLC25A30 (Haguenauer et al., 2005 [PubMed 15809292]).[supplied by OMIM, Mar 2008] Expression Broad expression in heart (RPKM 22.8), kidney (RPKM 18.0) and 24 other tissues See more Orthologs mouse all
SLC25A30-AS1, Official Symbol SLC25A30-AS1provided by HGNC Official Full Name SLC25A30 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:42795 See related Ensembl:ENSG00000251015 AllianceGenome:HGNC:42795 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
SLC25A31, Official Symbol SLC25A31provided by HGNC Official Full Name solute carrier family 25 member 31provided by HGNC Primary source HGNC:HGNC:25319 See related Ensembl:ENSG00000151475 MIM:610796; AllianceGenome:HGNC:25319 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAC4; ANT4; ANT 4; SFEC35kDa Summary The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] Expression Restricted expression toward testis (RPKM 32.1) See more Orthologs mouse all
SLC25A32, Official Symbol SLC25A32provided by HGNC Official Full Name solute carrier family 25 member 32provided by HGNC Primary source HGNC:HGNC:29683 See related Ensembl:ENSG00000164933 MIM:138480; AllianceGenome:HGNC:29683 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MFT; GLYB; MFTC; RREI Summary This gene encodes a member of the P(I/L)W subfamily of mitochondrial carrier family transport proteins. The encoded protein transports folate across the inner mitochondrial membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013] Expression Ubiquitous expression in appendix (RPKM 5.6), lymph node (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
SLC25A33, Official Symbol SLC25A33provided by HGNC Official Full Name solute carrier family 25 member 33provided by HGNC Primary source HGNC:HGNC:29681 See related Ensembl:ENSG00000171612 MIM:610816; AllianceGenome:HGNC:29681 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PNC1; BMSC-MCP Summary SLC25A33 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 27.8), fat (RPKM 18.2) and 23 other tissues See more Orthologs mouse all
SLC25A34, Official Symbol SLC25A34provided by HGNC Official Full Name solute carrier family 25 member 34provided by HGNC Primary source HGNC:HGNC:27653 See related Ensembl:ENSG00000162461 MIM:610817; AllianceGenome:HGNC:27653 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary SLC25A34 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Broad expression in duodenum (RPKM 4.5), small intestine (RPKM 4.4) and 22 other tissues See more Orthologs mouse all
SLC25A34-AS1, Official Symbol SLC25A34-AS1provided by HGNC Official Full Name SLC25A34 and TMEM82 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53623 See related Ensembl:ENSG00000224459 AllianceGenome:HGNC:53623 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A35, Official Symbol SLC25A35provided by HGNC Official Full Name solute carrier family 25 member 35provided by HGNC Primary source HGNC:HGNC:31921 See related Ensembl:ENSG00000125434 MIM:610818; AllianceGenome:HGNC:31921 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary SLC25A35 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 9.0), endometrium (RPKM 4.9) and 24 other tissues See more Orthologs mouse all
SLC25A36, Official Symbol SLC25A36provided by HGNC Official Full Name solute carrier family 25 member 36provided by HGNC Primary source HGNC:HGNC:25554 See related Ensembl:ENSG00000114120 MIM:616149; AllianceGenome:HGNC:25554 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HHF8; PNC2 Summary Enables pyrimidine nucleotide transmembrane transporter activity. Involved in mitochondrial genome maintenance; pyrimidine nucleotide transport; and regulation of mitochondrial membrane potential. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 19.4), endometrium (RPKM 15.5) and 24 other tissues See more Orthologs mouse all
SLC25A36P1, Official Symbol SLC25A36P1provided by HGNC Official Full Name SLC25A36 pseudogene 1provided by HGNC Primary source HGNC:HGNC:48935 See related Ensembl:ENSG00000267781 AllianceGenome:HGNC:48935 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A37, Official Symbol SLC25A37provided by HGNC Official Full Name solute carrier family 25 member 37provided by HGNC Primary source HGNC:HGNC:29786 See related Ensembl:ENSG00000147454 MIM:610387; AllianceGenome:HGNC:29786 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MSC; MFRN; MSCP; HT015; MFRN1; PRO1278; PRO1584; PRO2217 Summary SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed 19805291]).[supplied by OMIM, Jan 2011] Expression Broad expression in bone marrow (RPKM 58.8), duodenum (RPKM 28.2) and 21 other tissues See more Orthologs mouse all
SLC25A38, Official Symbol SLC25A38provided by HGNC Official Full Name solute carrier family 25 member 38provided by HGNC Primary source HGNC:HGNC:26054 See related Ensembl:ENSG00000144659 MIM:610819; AllianceGenome:HGNC:26054 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIDBA2 Summary This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia (anemia, sideroblastic, 2, pyridoxine-refractory). A related pseudogene is found on chromosome 1. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in thyroid (RPKM 14.1), bone marrow (RPKM 11.1) and 25 other tissues See more Orthologs mouse all
SLC25A38P1, Official Symbol SLC25A38P1provided by HGNC Official Full Name SLC25A38 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43858 See related AllianceGenome:HGNC:43858 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A39, Official Symbol SLC25A39provided by HGNC Official Full Name solute carrier family 25 member 39provided by HGNC Primary source HGNC:HGNC:24279 See related Ensembl:ENSG00000013306 MIM:610820; AllianceGenome:HGNC:24279 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGI69; CGI-69 Summary This gene encodes a member of the SLC25 transporter or mitochondrial carrier family of proteins. Members of this family are encoded by the nuclear genome while their protein products are usually embedded in the inner mitochondrial membrane and exhibit wide-ranging substrate specificity. Although the encoded protein is currently considered an orphan transporter, this protein is related to other carriers known to transport amino acids. This protein may play a role in iron homeostasis. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in bone marrow (RPKM 112.9), kidney (RPKM 47.3) and 25 other tissues See more Orthologs mouse all
SLC25A39P2, Official Symbol SLC25A39P2provided by HGNC Official Full Name SLC25A39 pseudogene 2provided by HGNC Primary source HGNC:HGNC:48936 See related Ensembl:ENSG00000257016 AllianceGenome:HGNC:48936 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SLC25A3P1, Official Symbol SLC25A3P1provided by HGNC Official Full Name solute carrier family 25 member 3 pseudogene 1provided by HGNC Primary source HGNC:HGNC:26869 See related Ensembl:ENSG00000236253 AllianceGenome:HGNC:26869 Gene type pseudo RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 2.3) See more
SLC25A4, Official Symbol SLC25A4provided by HGNC Official Full Name solute carrier family 25 member 4provided by HGNC Primary source HGNC:HGNC:10990 See related Ensembl:ENSG00000151729 MIM:103220; AllianceGenome:HGNC:10990 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as T1; ANT; AAC1; ANT1; PEO2; PEO3; ANT 1; PEOA2; MTDPS12; MTDPS12A Summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Jun 2013] Expression Biased expression in heart (RPKM 227.6), brain (RPKM 24.6) and 3 other tissues See more Orthologs mouse all
SLC25A40, Official Symbol SLC25A40provided by HGNC Official Full Name solute carrier family 25 member 40provided by HGNC Primary source HGNC:HGNC:29680 See related Ensembl:ENSG00000075303 MIM:610821; AllianceGenome:HGNC:29680 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCFP Summary SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in lymph node (RPKM 7.5), appendix (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
SLC25A41, Official Symbol SLC25A41provided by HGNC Official Full Name solute carrier family 25 member 41provided by HGNC Primary source HGNC:HGNC:28533 See related Ensembl:ENSG00000181240 MIM:610822; AllianceGenome:HGNC:28533 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APC4; SCaMC-3L Summary SLC25A41 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 3.0), brain (RPKM 0.8) and 14 other tissues See more Orthologs mouse all
SLC25A42, Official Symbol SLC25A42provided by HGNC Official Full Name solute carrier family 25 member 42provided by HGNC Primary source HGNC:HGNC:28380 See related Ensembl:ENSG00000181035 MIM:610823; AllianceGenome:HGNC:28380 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MECREN Summary This gene encodes a solute carrier family 25 protein. Solute carrier family 25 proteins are localized to mitochondria and play critical roles in the transport of molecules across the inner mitochondrial membrane. The encoded protein is a mitochondrial transporter for coenzyme A (CoA) and adenosine 3',5'-diphosphate. [provided by RefSeq, Feb 2012] Expression Broad expression in kidney (RPKM 18.3), liver (RPKM 12.3) and 24 other tissues See more Orthologs mouse all
SLC25A43, Official Symbol SLC25A43provided by HGNC Official Full Name solute carrier family 25 member 43provided by HGNC Primary source HGNC:HGNC:30557 See related Ensembl:ENSG00000077713 MIM:300641; AllianceGenome:HGNC:30557 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the mitochondrial carrier family of proteins.[provided by RefSeq, Dec 2009] Expression Ubiquitous expression in esophagus (RPKM 7.3), colon (RPKM 5.4) and 25 other tissues See more Orthologs mouse all
SLC25A44, Official Symbol SLC25A44provided by HGNC Official Full Name solute carrier family 25 member 44provided by HGNC Primary source HGNC:HGNC:29036 See related Ensembl:ENSG00000160785 MIM:610824; AllianceGenome:HGNC:29036 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary SLC25A44 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 13.3), kidney (RPKM 10.2) and 25 other tissues See more Orthologs mouse all
SLC25A45, Official Symbol SLC25A45provided by HGNC Official Full Name solute carrier family 25 member 45provided by HGNC Primary source HGNC:HGNC:27442 See related Ensembl:ENSG00000162241 MIM:610825; AllianceGenome:HGNC:27442 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary SLC25A45 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in spleen (RPKM 5.2), lymph node (RPKM 4.1) and 25 other tissues See more Orthologs mouse all
SLC25A46, Official Symbol SLC25A46provided by HGNC Official Full Name solute carrier family 25 member 46provided by HGNC Primary source HGNC:HGNC:25198 See related Ensembl:ENSG00000164209 MIM:610826; AllianceGenome:HGNC:25198 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCH1E; HMSN6B Summary This gene encodes a mitochondrial solute carrier protein family member. It functions in promoting mitochondrial fission, and prevents the formation of hyperfilamentous mitochondria. Mutation of this gene results in neuropathy and optic atrophy. [provided by RefSeq, Aug 2016] Expression Ubiquitous expression in brain (RPKM 17.7), thyroid (RPKM 13.2) and 25 other tissues See more Orthologs mouse all
SLC25A47, Official Symbol SLC25A47provided by HGNC Official Full Name solute carrier family 25 member 47provided by HGNC Primary source HGNC:HGNC:20115 See related Ensembl:ENSG00000140107 MIM:609911; AllianceGenome:HGNC:20115 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HDCMP; HDMCP; C14orf68; HMFN1655 Summary This gene encodes a member of a large family of mitochondrial transporters. The nuclear-encoded carrier protein is embedded in the inner mitochondrial membrane. This member of the family is thought to be an uncoupling protein that uncouples mitochondrial respiration from ATP synthesis by dissipating the transmembrane proton gradient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017] Expression Restricted expression toward liver (RPKM 73.4) See more Orthologs mouse all
SLC25A48, Official Symbol SLC25A48provided by HGNC Official Full Name solute carrier family 25 member 48provided by HGNC Primary source HGNC:HGNC:30451 See related Ensembl:ENSG00000145832 MIM:616150; AllianceGenome:HGNC:30451 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable acyl carnitine transmembrane transporter activity. Predicted to be involved in acyl carnitine transport and amino acid transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 2.6), skin (RPKM 1.9) and 10 other tissues See more Orthologs mouse all
SLC25A48-AS1, Official Symbol SLC25A48-AS1provided by HGNC Official Full Name SLC25A48 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:27965 See related Ensembl:ENSG00000251045 AllianceGenome:HGNC:27965 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LINC01959 Expression Low expression observed in reference dataset See more
SLC25A5, Official Symbol SLC25A5provided by HGNC Official Full Name solute carrier family 25 member 5provided by HGNC Primary source HGNC:HGNC:10991 See related Ensembl:ENSG00000005022 MIM:300150; AllianceGenome:HGNC:10991 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as T2; T3; 2F1; AAC2; ANT2 Summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013] Expression Ubiquitous expression in duodenum (RPKM 370.1), small intestine (RPKM 299.2) and 25 other tissues See more Orthologs mouse all