psui3905/ncbi_genes_summary huggingface dataset:
APIP, Official Symbol APIPprovided by HGNC Official Full Name APAF1 interacting proteinprovided by HGNC Primary source HGNC:HGNC:17581 See related Ensembl:ENSG00000149089 MIM:612491; AllianceGenome:HGNC:17581 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APIP2; CGI29; hAPIP; CGI-29; MMRP19 Summary Enables identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in several processes, including L-methionine salvage from methylthioadenosine; protein homotetramerization; and pyroptosis. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 15.7), adrenal (RPKM 13.7) and 25 other tissues See more Orthologs mouse all
APLF, Official Symbol APLFprovided by HGNC Official Full Name aprataxin and PNKP like factorprovided by HGNC Primary source HGNC:HGNC:28724 See related Ensembl:ENSG00000169621 MIM:611035; AllianceGenome:HGNC:28724 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APFL; PALF; Xip1; ZCCHH1; C2orf13 Summary Enables DNA-(apurinic or apyrimidinic site) endonuclease activity; nuclease activity; and nucleotide binding activity. Involved in double-strand break repair via nonhomologous end joining and single strand break repair. Acts upstream of or within positive regulation of DNA ligation. Located in nucleoplasm. Is active in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 1.6), skin (RPKM 1.2) and 24 other tissues See more Orthologs mouse all
APLN, Official Symbol APLNprovided by HGNC Official Full Name apelinprovided by HGNC Primary source HGNC:HGNC:16665 See related Ensembl:ENSG00000171388 MIM:300297; AllianceGenome:HGNC:16665 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APEL; XNPEP2 Summary This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016] Expression Biased expression in placenta (RPKM 42.1), lung (RPKM 12.5) and 5 other tissues See more Orthologs mouse all
APLNR, Official Symbol APLNRprovided by HGNC Official Full Name apelin receptorprovided by HGNC Primary source HGNC:HGNC:339 See related Ensembl:ENSG00000134817 MIM:600052; AllianceGenome:HGNC:339 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APJ; APJR; HG11; AGTRL1 Summary This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009] Expression Biased expression in spleen (RPKM 57.2), placenta (RPKM 39.1) and 11 other tissues See more Orthologs mouse all
APLP1, Official Symbol APLP1provided by HGNC Official Full Name amyloid beta precursor like protein 1provided by HGNC Primary source HGNC:HGNC:597 See related Ensembl:ENSG00000105290 MIM:104775; AllianceGenome:HGNC:597 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APLP Summary This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 172.7) and adrenal (RPKM 17.0) See more Orthologs mouse all
APLP2, Official Symbol APLP2provided by HGNC Official Full Name amyloid beta precursor like protein 2provided by HGNC Primary source HGNC:HGNC:598 See related Ensembl:ENSG00000084234 MIM:104776; AllianceGenome:HGNC:598 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APPH; APPL2; CDEBP; APLP-2 Summary This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in thyroid (RPKM 347.8), lung (RPKM 236.7) and 24 other tissues See more Orthologs mouse all
APMAP, Official Symbol APMAPprovided by HGNC Official Full Name adipocyte plasma membrane associated proteinprovided by HGNC Primary source HGNC:HGNC:13238 See related Ensembl:ENSG00000101474 MIM:615884; AllianceGenome:HGNC:13238 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BSCv; C20orf3 Summary Enables arylesterase activity. Predicted to be involved in biosynthetic process. Located in cell surface and membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 46.5), fat (RPKM 34.1) and 24 other tissues See more Orthologs mouse all
APOA1, Official Symbol APOA1provided by HGNC Official Full Name apolipoprotein A1provided by HGNC Primary source HGNC:HGNC:600 See related Ensembl:ENSG00000118137 MIM:107680; AllianceGenome:HGNC:600 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPALP2; apo(a) Summary This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015] Expression Biased expression in liver (RPKM 4032.4), small intestine (RPKM 1199.8) and 1 other tissue See more Orthologs mouse all
APOA1-AS, Official Symbol APOA1-ASprovided by HGNC Official Full Name APOA1 antisense RNAprovided by HGNC Primary source HGNC:HGNC:40079 See related Ensembl:ENSG00000235910 MIM:620112; AllianceGenome:HGNC:40079 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in liver (RPKM 736.4), small intestine (RPKM 388.1) and 1 other tissue See more
APOA2, Official Symbol APOA2provided by HGNC Official Full Name apolipoprotein A2provided by HGNC Primary source HGNC:HGNC:601 See related Ensembl:ENSG00000158874 MIM:107670; AllianceGenome:HGNC:601 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as apoAII; Apo-AII; ApoA-II Summary This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008] Expression Restricted expression toward liver (RPKM 5129.5) See more Orthologs mouse all
APOA4, Official Symbol APOA4provided by HGNC Official Full Name apolipoprotein A4provided by HGNC Primary source HGNC:HGNC:602 See related Ensembl:ENSG00000110244 MIM:107690; AllianceGenome:HGNC:602 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008] Expression Restricted expression toward small intestine (RPKM 1486.2) See more Orthologs mouse all
APOA5, Official Symbol APOA5provided by HGNC Official Full Name apolipoprotein A5provided by HGNC Primary source HGNC:HGNC:17288 See related Ensembl:ENSG00000110243 MIM:606368; AllianceGenome:HGNC:17288 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAP3; APOAV Summary The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009] Expression Restricted expression toward liver (RPKM 62.5) See more Orthologs mouse all
APOB, Official Symbol APOBprovided by HGNC Official Full Name apolipoprotein Bprovided by HGNC Primary source HGNC:HGNC:603 See related Ensembl:ENSG00000084674 MIM:107730; AllianceGenome:HGNC:603 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLDB; FCHL2; LDLCQ4; apoB-48; apoB-100 Summary This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins (LDL), and is the ligand for the LDL receptor. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Dec 2019] Expression Biased expression in liver (RPKM 415.6), small intestine (RPKM 182.7) and 1 other tissue See more Orthologs mouse all
APOBEC1, Official Symbol APOBEC1provided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 1provided by HGNC Primary source HGNC:HGNC:604 See related Ensembl:ENSG00000111701 MIM:600130; AllianceGenome:HGNC:604 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APO1; BEDP; HEPR; CDAR1; APOBEC-1 Summary This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015] Expression Biased expression in duodenum (RPKM 22.2), small intestine (RPKM 18.5) and 1 other tissue See more Orthologs mouse all
APOBEC2, Official Symbol APOBEC2provided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 2provided by HGNC Primary source HGNC:HGNC:605 See related Ensembl:ENSG00000124701 MIM:604797; AllianceGenome:HGNC:605 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARP1; ARCD1 Summary Enables cytidine deaminase activity and identical protein binding activity. Involved in DNA demethylation. Acts upstream of or within cytidine to uridine editing. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in heart (RPKM 45.3), prostate (RPKM 9.9) and 1 other tissue See more Orthologs mouse all
APOBEC3A, Official Symbol APOBEC3Aprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Aprovided by HGNC Primary source HGNC:HGNC:17343 See related Ensembl:ENSG00000128383 MIM:607109; AllianceGenome:HGNC:17343 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3A; ARP3; PHRBN; bK150C2.1 Summary This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] Expression Biased expression in bone marrow (RPKM 38.8), appendix (RPKM 13.8) and 5 other tissues See more Orthologs all
APOBEC3AP1, Official Symbol APOBEC3AP1provided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3A pseudogene 1provided by HGNC Primary source HGNC:HGNC:43835 See related Ensembl:ENSG00000248822 AllianceGenome:HGNC:43835 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
APOBEC3B, Official Symbol APOBEC3Bprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Bprovided by HGNC Primary source HGNC:HGNC:17352 See related Ensembl:ENSG00000179750 MIM:607110; AllianceGenome:HGNC:17352 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3B; ARP4; ARCD3; PHRBNL; APOBEC1L; bK150C2.2; DJ742C19.2 Summary This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] Expression Biased expression in bone marrow (RPKM 23.5), appendix (RPKM 8.8) and 12 other tissues See more Orthologs all
APOBEC3B-AS1, Official Symbol APOBEC3B-AS1provided by HGNC Official Full Name APOBEC3B antisense RNA 1provided by HGNC Primary source HGNC:HGNC:43836 See related Ensembl:ENSG00000249310 AllianceGenome:HGNC:43836 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in bone marrow (RPKM 17.0), appendix (RPKM 7.1) and 11 other tissues See more
APOBEC3C, Official Symbol APOBEC3Cprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Cprovided by HGNC Primary source HGNC:HGNC:17353 See related Ensembl:ENSG00000244509 MIM:607750; AllianceGenome:HGNC:17353 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3 Summary This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 33.1), testis (RPKM 26.8) and 24 other tissues See more Orthologs all
APOBEC3D, Official Symbol APOBEC3Dprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Dprovided by HGNC Primary source HGNC:HGNC:17354 See related Ensembl:ENSG00000243811 MIM:609900; AllianceGenome:HGNC:17354 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3D; A3DE; ARP6; APOBEC3E; APOBEC3DE Summary This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 5.2), spleen (RPKM 4.6) and 22 other tissues See more Orthologs all
APOBEC3F, Official Symbol APOBEC3Fprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Fprovided by HGNC Primary source HGNC:HGNC:17356 See related Ensembl:ENSG00000128394 MIM:608993; AllianceGenome:HGNC:17356 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3F; KA6; ARP8; BK150C2.4.MRNA Summary This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 2.8), ovary (RPKM 2.8) and 24 other tissues See more Orthologs all
APOBEC3G, Official Symbol APOBEC3Gprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Gprovided by HGNC Primary source HGNC:HGNC:17357 See related Ensembl:ENSG00000239713 MIM:607113; AllianceGenome:HGNC:17357 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3G; ARCD; ARP9; ARP-9; CEM15; CEM-15; MDS019; bK150C2.7; dJ494G10.1 Summary This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Mar 2017] Expression Broad expression in lymph node (RPKM 19.7), spleen (RPKM 13.4) and 22 other tissues See more Orthologs all
APOBEC3H, Official Symbol APOBEC3Hprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Hprovided by HGNC Primary source HGNC:HGNC:24100 See related Ensembl:ENSG00000100298 MIM:610976; AllianceGenome:HGNC:24100 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3H; ARP10; ARP-10 Summary This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] Expression Broad expression in lymph node (RPKM 1.2), colon (RPKM 1.0) and 22 other tissues See more Orthologs mouse all
APOBEC4, Official Symbol APOBEC4provided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4provided by HGNC Primary source HGNC:HGNC:32152 See related Ensembl:ENSG00000173627 MIM:609908; AllianceGenome:HGNC:32152 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf169 Summary This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 6.1) See more Orthologs mouse all
APOBR, Official Symbol APOBRprovided by HGNC Official Full Name apolipoprotein B receptorprovided by HGNC Primary source HGNC:HGNC:24087 See related Ensembl:ENSG00000184730 MIM:605220; AllianceGenome:HGNC:24087 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOB48R; APOB100R Summary Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 19.1), spleen (RPKM 14.5) and 12 other tissues See more Orthologs mouse all
APOC1, Official Symbol APOC1provided by HGNC Official Full Name apolipoprotein C1provided by HGNC Primary source HGNC:HGNC:607 See related Ensembl:ENSG00000130208 MIM:107710; AllianceGenome:HGNC:607 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Apo-CI; ApoC-I; apo-CIB; apoC-IB Summary This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016] Expression Biased expression in liver (RPKM 1936.2) and adrenal (RPKM 201.2) See more Orthologs mouse all
APOC2, Official Symbol APOC2provided by HGNC Official Full Name apolipoprotein C2provided by HGNC Primary source HGNC:HGNC:609 See related Ensembl:ENSG00000234906 MIM:608083; AllianceGenome:HGNC:609 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APO-CII; APOC-II Summary This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011] Expression Restricted expression toward liver (RPKM 1243.9) See more Orthologs mouse all
APOC3, Official Symbol APOC3provided by HGNC Official Full Name apolipoprotein C3provided by HGNC Primary source HGNC:HGNC:610 See related Ensembl:ENSG00000110245 MIM:107720; AllianceGenome:HGNC:610 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Apo-C3; ApoC-3; APOCIII Summary This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017] Expression Restricted expression toward liver (RPKM 3180.7) See more Orthologs mouse all
APOC4, Official Symbol APOC4provided by HGNC Official Full Name apolipoprotein C4provided by HGNC Primary source HGNC:HGNC:611 See related Ensembl:ENSG00000267467 MIM:600745; AllianceGenome:HGNC:611 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APO-CIV; APOC-IV Summary This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011] Expression Restricted expression toward liver (RPKM 124.3) See more Orthologs mouse all
APOD, Official Symbol APODprovided by HGNC Official Full Name apolipoprotein Dprovided by HGNC Primary source HGNC:HGNC:612 See related Ensembl:ENSG00000189058 MIM:107740; AllianceGenome:HGNC:612 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008] Expression Broad expression in fat (RPKM 368.7), brain (RPKM 153.2) and 16 other tissues See more Orthologs mouse all
APOE, Official Symbol APOEprovided by HGNC Official Full Name apolipoprotein Eprovided by HGNC Primary source HGNC:HGNC:613 See related Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AD2; LPG; APO-E; ApoE4; LDLCQ5 Summary The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] Expression Biased expression in liver (RPKM 1021.7), kidney (RPKM 648.1) and 7 other tissues See more Orthologs mouse all
APOF, Official Symbol APOFprovided by HGNC Official Full Name apolipoprotein Fprovided by HGNC Primary source HGNC:HGNC:615 See related Ensembl:ENSG00000175336 MIM:107760; AllianceGenome:HGNC:615 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LTIP; Apo-F Summary The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008] Expression Restricted expression toward liver (RPKM 110.1) See more Orthologs mouse all
APOH, Official Symbol APOHprovided by HGNC Official Full Name apolipoprotein Hprovided by HGNC Primary source HGNC:HGNC:616 See related Ensembl:ENSG00000091583 MIM:138700; AllianceGenome:HGNC:616 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BG; B2G1; B2GP1 Summary Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019] Expression Restricted expression toward liver (RPKM 3533.3) See more Orthologs mouse all
APOL1, Official Symbol APOL1provided by HGNC Official Full Name apolipoprotein L1provided by HGNC Primary source HGNC:HGNC:618 See related Ensembl:ENSG00000100342 MIM:603743; AllianceGenome:HGNC:618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOL; APO-L; FSGS4; APOL-I Summary This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] Expression Ubiquitous expression in liver (RPKM 56.2), urinary bladder (RPKM 39.7) and 21 other tissues See more Orthologs all
APOL2, Official Symbol APOL2provided by HGNC Official Full Name apolipoprotein L2provided by HGNC Primary source HGNC:HGNC:619 See related Ensembl:ENSG00000128335 MIM:607252; AllianceGenome:HGNC:619 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOL3; APOL-II Summary This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in appendix (RPKM 11.5), spleen (RPKM 10.5) and 25 other tissues See more Orthologs all
APOL3, Official Symbol APOL3provided by HGNC Official Full Name apolipoprotein L3provided by HGNC Primary source HGNC:HGNC:14868 See related Ensembl:ENSG00000128284 MIM:607253; AllianceGenome:HGNC:14868 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CG121; CG12_1; APOLIII; apoL-III Summary This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] Expression Broad expression in spleen (RPKM 16.1), fat (RPKM 13.1) and 24 other tissues See more Orthologs all
APOL4, Official Symbol APOL4provided by HGNC Official Full Name apolipoprotein L4provided by HGNC Primary source HGNC:HGNC:14867 See related Ensembl:ENSG00000100336 MIM:607254; AllianceGenome:HGNC:14867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOLIV; APOL-IV Summary This gene encodes a member of the apolipoprotein L family. The encoded protein may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2020] Expression Broad expression in prostate (RPKM 5.7), lung (RPKM 5.4) and 24 other tissues See more Orthologs all
APOL5, Official Symbol APOL5provided by HGNC Official Full Name apolipoprotein L5provided by HGNC Primary source HGNC:HGNC:14869 See related Ensembl:ENSG00000128313 MIM:607255; AllianceGenome:HGNC:14869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOLV; APOL-V Summary This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs all
APOL6, Official Symbol APOL6provided by HGNC Official Full Name apolipoprotein L6provided by HGNC Primary source HGNC:HGNC:14870 See related Ensembl:ENSG00000221963 MIM:607256; AllianceGenome:HGNC:14870 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APOLVI; APOL-VI Summary This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 14.3), liver (RPKM 13.1) and 24 other tissues See more Orthologs mouse all
APOLD1, Official Symbol APOLD1provided by HGNC Official Full Name apolipoprotein L domain containing 1provided by HGNC Primary source HGNC:HGNC:25268 See related Ensembl:ENSG00000178878 MIM:612456; AllianceGenome:HGNC:25268 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VERGE Summary APOLD1 is an endothelial cell early response protein that may play a role in regulation of endothelial cell signaling and vascular function (Regard et al., 2004 [PubMed 15102925]).[supplied by OMIM, Dec 2008] Expression Broad expression in fat (RPKM 54.0), thyroid (RPKM 52.1) and 18 other tissues See more Orthologs mouse all
APOM, Official Symbol APOMprovided by HGNC Official Full Name apolipoprotein Mprovided by HGNC Primary source HGNC:HGNC:13916 See related Ensembl:ENSG00000204444 MIM:606907; AllianceGenome:HGNC:13916 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G3a; NG20; apo-M; HSPC336 Summary The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] Expression Biased expression in liver (RPKM 122.3), kidney (RPKM 73.7) and 1 other tissue See more Orthologs mouse all
APOO, Official Symbol APOOprovided by HGNC Official Full Name apolipoprotein Oprovided by HGNC Primary source HGNC:HGNC:28727 See related Ensembl:ENSG00000184831 MIM:300753; AllianceGenome:HGNC:28727 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIC26; Mic23; My025; FAM121B; MICOS26 Summary This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009] Expression Ubiquitous expression in heart (RPKM 9.7), brain (RPKM 7.6) and 25 other tissues See more Orthologs mouse all
APOOL, Official Symbol APOOLprovided by HGNC Official Full Name apolipoprotein O likeprovided by HGNC Primary source HGNC:HGNC:24009 See related Ensembl:ENSG00000155008 MIM:300955; AllianceGenome:HGNC:24009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Mic27; CXorf33; FAM121A; MICOS27; UNQ8193 Summary This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in brain (RPKM 7.7), thyroid (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
APOOP1, Official Symbol APOOP1provided by HGNC Official Full Name apolipoprotein O pseudogene 1provided by HGNC Primary source HGNC:HGNC:48739 See related AllianceGenome:HGNC:48739 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
APOOP2, Official Symbol APOOP2provided by HGNC Official Full Name apolipoprotein O pseudogene 2provided by HGNC Primary source HGNC:HGNC:48740 See related Ensembl:ENSG00000240902 AllianceGenome:HGNC:48740 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
APOOP5, Official Symbol APOOP5provided by HGNC Official Full Name apolipoprotein O pseudogene 5provided by HGNC Primary source HGNC:HGNC:48743 See related AllianceGenome:HGNC:48743 Gene type pseudo RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo