psui3905/ncbi_genes_summary huggingface dataset:
TRIM50, Official Symbol TRIM50provided by HGNC Official Full Name tripartite motif containing 50provided by HGNC Primary source HGNC:HGNC:19017 See related Ensembl:ENSG00000146755 MIM:612548; AllianceGenome:HGNC:19017 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM50A Summary Enables identical protein binding activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within regulation of establishment of protein localization. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in stomach (RPKM 3.4), testis (RPKM 2.8) and 8 other tissues See more Orthologs mouse all
TRIM51, Official Symbol TRIM51provided by HGNC Official Full Name tripartite motif-containing 51provided by HGNC Primary source HGNC:HGNC:19023 See related Ensembl:ENSG00000124900 AllianceGenome:HGNC:19023 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPRYD5; TRIM51A Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TRIM51BP, Official Symbol TRIM51BPprovided by HGNC Official Full Name tripartite motif-containing 51B, pseudogeneprovided by HGNC Primary source HGNC:HGNC:37145 See related Ensembl:ENSG00000204455 AllianceGenome:HGNC:37145 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPRYD5P; SPRYD5P1
TRIM51CP, Official Symbol TRIM51CPprovided by HGNC Official Full Name tripartite motif-containing 51C, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43968 See related Ensembl:ENSG00000249910 AllianceGenome:HGNC:43968 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM51EP, Official Symbol TRIM51EPprovided by HGNC Official Full Name tripartite motif-containing 51E, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43970 See related AllianceGenome:HGNC:43970 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
TRIM51FP, Official Symbol TRIM51FPprovided by HGNC Official Full Name tripartite motif-containing 51F, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43966 See related AllianceGenome:HGNC:43966 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF18B; TRIM49B
TRIM52, Official Symbol TRIM52provided by HGNC Official Full Name tripartite motif containing 52provided by HGNC Primary source HGNC:HGNC:19024 See related Ensembl:ENSG00000183718 MIM:619265; AllianceGenome:HGNC:19024 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF102 Summary Enables transcription coactivator activity and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of NF-kappaB transcription factor activity; and protein autoubiquitination. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 9.5), spleen (RPKM 9.1) and 25 other tissues See more Orthologs all
TRIM52-AS1, Official Symbol TRIM52-AS1provided by HGNC Official Full Name TRIM52 antisense RNA 1 (head to head)provided by HGNC Primary source HGNC:HGNC:49006 See related Ensembl:ENSG00000248275 MIM:619266; AllianceGenome:HGNC:49006 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in fat (RPKM 3.9), thyroid (RPKM 3.5) and 25 other tissues See more
TRIM53AP, Official Symbol TRIM53APprovided by HGNC Official Full Name tripartite motif containing 53A, pseudogeneprovided by HGNC Primary source HGNC:HGNC:19025 See related Ensembl:ENSG00000225581 AllianceGenome:HGNC:19025 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM53; TRIM53P; TRIM80P Expression Low expression observed in reference dataset See more
TRIM53CP, Official Symbol TRIM53CPprovided by HGNC Official Full Name tripartite motif containing 53C, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43979 See related Ensembl:ENSG00000254764 AllianceGenome:HGNC:43979 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM54, Official Symbol TRIM54provided by HGNC Official Full Name tripartite motif containing 54provided by HGNC Primary source HGNC:HGNC:16008 See related Ensembl:ENSG00000138100 MIM:606474; AllianceGenome:HGNC:16008 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MURF; RNF30; muRF3; MURF-3 Summary The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 35.4), testis (RPKM 5.2) and 2 other tissues See more Orthologs mouse all
TRIM55, Official Symbol TRIM55provided by HGNC Official Full Name tripartite motif containing 55provided by HGNC Primary source HGNC:HGNC:14215 See related Ensembl:ENSG00000147573 MIM:606469; AllianceGenome:HGNC:14215 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF29; muRF2; MURF-2 Summary The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 14.3), liver (RPKM 6.5) and 2 other tissues See more Orthologs mouse all
TRIM56, Official Symbol TRIM56provided by HGNC Official Full Name tripartite motif containing 56provided by HGNC Primary source HGNC:HGNC:19028 See related Ensembl:ENSG00000169871 MIM:616996; AllianceGenome:HGNC:19028 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF109 Summary Enables RNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of macromolecule metabolic process; and protein K63-linked ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 9.3), ovary (RPKM 7.5) and 25 other tissues See more Orthologs mouse all
TRIM58, Official Symbol TRIM58provided by HGNC Official Full Name tripartite motif containing 58provided by HGNC Primary source HGNC:HGNC:24150 See related Ensembl:ENSG00000162722 AllianceGenome:HGNC:24150 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIA2 Summary Predicted to enable dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in bone marrow (RPKM 12.4), thyroid (RPKM 11.2) and 5 other tissues See more Orthologs mouse all
TRIM59, Official Symbol TRIM59provided by HGNC Official Full Name tripartite motif containing 59provided by HGNC Primary source HGNC:HGNC:30834 See related Ensembl:ENSG00000213186 MIM:616148; AllianceGenome:HGNC:30834 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRF1; TSBF1; IFT80L; RNF104; TRIM57 Summary Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 4.6), lymph node (RPKM 4.6) and 21 other tissues See more Orthologs mouse all
TRIM6, Official Symbol TRIM6provided by HGNC Official Full Name tripartite motif containing 6provided by HGNC Primary source HGNC:HGNC:16277 See related Ensembl:ENSG00000121236 MIM:607564; AllianceGenome:HGNC:16277 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF89 Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010] Expression Broad expression in kidney (RPKM 10.6), testis (RPKM 6.4) and 15 other tissues See more Orthologs mouse all
TRIM6-TRIM34, Official Symbol TRIM6-TRIM34provided by HGNC Official Full Name TRIM6-TRIM34 readthroughprovided by HGNC Primary source HGNC:HGNC:33440 See related Ensembl:ENSG00000258588 AllianceGenome:HGNC:33440 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IFP1; RNF21; RNF89; TRIM6; TRIM34 Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene represents a readthrough transcript from genes TRIM6 and TRIM34, and it was described as a splice variant of TRIM34. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. [provided by RefSeq, Nov 2009] Expression Ubiquitous expression in spleen (RPKM 5.9), kidney (RPKM 5.3) and 24 other tissues See more Orthologs all
TRIM60, Official Symbol TRIM60provided by HGNC Official Full Name tripartite motif containing 60provided by HGNC Primary source HGNC:HGNC:21162 See related Ensembl:ENSG00000176979 MIM:619416; AllianceGenome:HGNC:21162 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF33; RNF129 Summary The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Pseudogenes of this gene are located on more than six chromosomes including chromosome 4. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013] Expression Low expression observed in reference dataset See more Orthologs mouse all
TRIM60P10Y, Official Symbol TRIM60P10Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 10, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38462 See related Ensembl:ENSG00000232976 AllianceGenome:HGNC:38462 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P10; TRIM60PY10
TRIM60P11Y, Official Symbol TRIM60P11Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 11, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38463 See related Ensembl:ENSG00000227837 AllianceGenome:HGNC:38463 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P11; TRIM60PY11
TRIM60P14, Official Symbol TRIM60P14provided by HGNC Official Full Name tripartite motif containing 60 pseudogene 14provided by HGNC Primary source HGNC:HGNC:38486 See related Ensembl:ENSG00000250227 AllianceGenome:HGNC:38486 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM60P15, Official Symbol TRIM60P15provided by HGNC Official Full Name tripartite motif containing 60 pseudogene 15provided by HGNC Primary source HGNC:HGNC:38487 See related AllianceGenome:HGNC:38487 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM60P16, Official Symbol TRIM60P16provided by HGNC Official Full Name tripartite motif containing 60 pseudogene 16provided by HGNC Primary source HGNC:HGNC:38488 See related Ensembl:ENSG00000229909 AllianceGenome:HGNC:38488 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM60P17, Official Symbol TRIM60P17provided by HGNC Official Full Name tripartite motif containing 60 pseudogene 17provided by HGNC Primary source HGNC:HGNC:38489 See related AllianceGenome:HGNC:38489 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM60P19, Official Symbol TRIM60P19provided by HGNC Official Full Name tripartite motif containing 60 pseudogene 19provided by HGNC Primary source HGNC:HGNC:42010 See related Ensembl:ENSG00000235737 AllianceGenome:HGNC:42010 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM60P3Y, Official Symbol TRIM60P3Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 3, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38409 See related Ensembl:ENSG00000227830 AllianceGenome:HGNC:38409 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P3; TRIM60PY3
TRIM60P5Y, Official Symbol TRIM60P5Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 5, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38430 See related Ensembl:ENSG00000224210 AllianceGenome:HGNC:38430 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P5; TRIM60PY5
TRIM60P8Y, Official Symbol TRIM60P8Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 8, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38458 See related Ensembl:ENSG00000232764 AllianceGenome:HGNC:38458 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P8; TRIM60PY8
TRIM60P9Y, Official Symbol TRIM60P9Yprovided by HGNC Official Full Name tripartite motif containing 60 pseudogene 9, Y-linkedprovided by HGNC Primary source HGNC:HGNC:38459 See related Ensembl:ENSG00000227251 AllianceGenome:HGNC:38459 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM60P9; TRIM60PY9
TRIM61, Official Symbol TRIM61provided by HGNC Official Full Name tripartite motif containing 61provided by HGNC Primary source HGNC:HGNC:24339 See related Ensembl:ENSG00000183439 MIM:619417; AllianceGenome:HGNC:24339 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF35 Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 4.2), thyroid (RPKM 2.0) and 17 other tissues See more Orthologs all
TRIM62, Official Symbol TRIM62provided by HGNC Official Full Name tripartite motif containing 62provided by HGNC Primary source HGNC:HGNC:25574 See related Ensembl:ENSG00000116525 MIM:616755; AllianceGenome:HGNC:25574 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEAR1 Summary Enables identical protein binding activity; transcription coactivator activity; and ubiquitin-protein transferase activity. Involved in several processes, including negative regulation of viral transcription; positive regulation of NF-kappaB transcription factor activity; and positive regulation of antifungal innate immune response. Is active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 2.0), brain (RPKM 1.3) and 25 other tissues See more Orthologs mouse all
TRIM63, Official Symbol TRIM63provided by HGNC Official Full Name tripartite motif containing 63provided by HGNC Primary source HGNC:HGNC:16007 See related Ensembl:ENSG00000158022 MIM:606131; AllianceGenome:HGNC:16007 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IRF; SMRZ; MURF1; MURF2; RNF28 Summary This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012] Expression Biased expression in heart (RPKM 44.7) and esophagus (RPKM 2.8) See more Orthologs mouse all
TRIM64, Official Symbol TRIM64provided by HGNC Official Full Name tripartite motif containing 64provided by HGNC Primary source HGNC:HGNC:14663 See related Ensembl:ENSG00000204450 AllianceGenome:HGNC:14663 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM64A; C11orf28 Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TRIM64B, Official Symbol TRIM64Bprovided by HGNC Official Full Name tripartite motif containing 64Bprovided by HGNC Primary source HGNC:HGNC:37147 See related Ensembl:ENSG00000189253 AllianceGenome:HGNC:37147 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TRIM64C, Official Symbol TRIM64Cprovided by HGNC Official Full Name tripartite motif containing 64Cprovided by HGNC Primary source HGNC:HGNC:37148 See related Ensembl:ENSG00000214891 AllianceGenome:HGNC:37148 Gene type protein coding RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TRIM64DP, Official Symbol TRIM64DPprovided by HGNC Official Full Name tripartite motif containing 64D, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43974 See related Ensembl:ENSG00000254751 AllianceGenome:HGNC:43974 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM64EP, Official Symbol TRIM64EPprovided by HGNC Official Full Name tripartite motif containing 64E, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43975 See related Ensembl:ENSG00000223709 AllianceGenome:HGNC:43975 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM64FP, Official Symbol TRIM64FPprovided by HGNC Official Full Name tripartite motif containing 64F, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43976 See related Ensembl:ENSG00000226185 AllianceGenome:HGNC:43976 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM65, Official Symbol TRIM65provided by HGNC Official Full Name tripartite motif containing 65provided by HGNC Primary source HGNC:HGNC:27316 See related Ensembl:ENSG00000141569 MIM:619408; AllianceGenome:HGNC:27316 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 4732463G12Rik Summary Predicted to enable zinc ion binding activity. Involved in positive regulation of autophagy. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 5.1), lung (RPKM 4.3) and 25 other tissues See more Orthologs mouse all
TRIM66, Official Symbol TRIM66provided by HGNC Official Full Name tripartite motif containing 66provided by HGNC Primary source HGNC:HGNC:29005 See related Ensembl:ENSG00000166436 MIM:612000; AllianceGenome:HGNC:29005 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIF1D; C11orf29; TIF1DELTA Summary Predicted to enable chromatin binding activity and identical protein binding activity. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Located in aggresome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 4.5), skin (RPKM 3.3) and 25 other tissues See more Orthologs mouse all
TRIM67, Official Symbol TRIM67provided by HGNC Official Full Name tripartite motif containing 67provided by HGNC Primary source HGNC:HGNC:31859 See related Ensembl:ENSG00000119283 MIM:610584; AllianceGenome:HGNC:31859 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TNL Summary Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of protein localization. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; and positive regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 4.1) and adrenal (RPKM 0.2) See more Orthologs mouse all
TRIM67-AS1, Official Symbol TRIM67-AS1provided by HGNC Official Full Name TRIM67 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41282 See related Ensembl:ENSG00000235710 AllianceGenome:HGNC:41282 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more Orthologs all
TRIM68, Official Symbol TRIM68provided by HGNC Official Full Name tripartite motif containing 68provided by HGNC Primary source HGNC:HGNC:21161 See related Ensembl:ENSG00000167333 MIM:613184; AllianceGenome:HGNC:21161 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SS56; GC109; SS-56; RNF137 Summary This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Ubiquitous expression in thyroid (RPKM 4.1), prostate (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
TRIM69, Official Symbol TRIM69provided by HGNC Official Full Name tripartite motif containing 69provided by HGNC Primary source HGNC:HGNC:17857 See related Ensembl:ENSG00000185880 MIM:616017; AllianceGenome:HGNC:17857 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Trif; HSD34; RNF36; HSD-34 Summary This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 19.8) and brain (RPKM 1.8) See more Orthologs mouse all
TRIM7, Official Symbol TRIM7provided by HGNC Official Full Name tripartite motif containing 7provided by HGNC Primary source HGNC:HGNC:16278 See related Ensembl:ENSG00000146054 MIM:609315; AllianceGenome:HGNC:16278 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GNIP; RNF90 Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Biased expression in skin (RPKM 5.6), esophagus (RPKM 2.8) and 8 other tissues See more Orthologs mouse all
TRIM71, Official Symbol TRIM71provided by HGNC Official Full Name tripartite motif containing 71provided by HGNC Primary source HGNC:HGNC:32669 See related Ensembl:ENSG00000206557 MIM:618570; AllianceGenome:HGNC:32669 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYC4; LIN41; HYDCC1; LIN-41 Summary The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015] Expression Biased expression in testis (RPKM 4.2), kidney (RPKM 0.7) and 1 other tissue See more Orthologs mouse all
TRIM72, Official Symbol TRIM72provided by HGNC Official Full Name tripartite motif containing 72provided by HGNC Primary source HGNC:HGNC:32671 See related Ensembl:ENSG00000177238 MIM:613288; AllianceGenome:HGNC:32671 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MG53 Summary Enables identical protein binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; plasma membrane repair; and protein homooligomerization. Predicted to act upstream of or within negative regulation of insulin receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in prostate (RPKM 2.0), esophagus (RPKM 0.3) and 1 other tissue See more Orthologs mouse all
TRIM73, Official Symbol TRIM73provided by HGNC Official Full Name tripartite motif containing 73provided by HGNC Primary source HGNC:HGNC:18162 See related Ensembl:ENSG00000178809 MIM:612549; AllianceGenome:HGNC:18162 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM50B Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 4.9), stomach (RPKM 3.6) and 24 other tissues See more Orthologs all
TRIM74, Official Symbol TRIM74provided by HGNC Official Full Name tripartite motif containing 74provided by HGNC Primary source HGNC:HGNC:17453 See related Ensembl:ENSG00000155428 MIM:612550; AllianceGenome:HGNC:17453 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM50C Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 13.0), bone marrow (RPKM 5.7) and 24 other tissues See more Orthologs all
TRIM77, Official Symbol TRIM77provided by HGNC Official Full Name tripartite motif containing 77provided by HGNC Primary source HGNC:HGNC:34228 See related Ensembl:ENSG00000214414 AllianceGenome:HGNC:34228 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM77P Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
TRIM77BP, Official Symbol TRIM77BPprovided by HGNC Official Full Name tripartite motif containing 77B, pseudogeneprovided by HGNC Primary source HGNC:HGNC:43980 See related Ensembl:ENSG00000254993 AllianceGenome:HGNC:43980 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TRIM8, Official Symbol TRIM8provided by HGNC Official Full Name tripartite motif containing 8provided by HGNC Primary source HGNC:HGNC:15579 See related Ensembl:ENSG00000171206 MIM:606125; AllianceGenome:HGNC:15579 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GERP; RNF27; FSGSNEDS Summary This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in kidney (RPKM 42.3), fat (RPKM 41.8) and 25 other tissues See more Orthologs mouse all
TRIM80P, Official Symbol TRIM80Pprovided by HGNC Official Full Name tripartite motif containing 80, pseudogeneprovided by HGNC Primary source HGNC:HGNC:51490 See related Ensembl:ENSG00000232724 AllianceGenome:HGNC:51490 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIM47LP
TRIM9, Official Symbol TRIM9provided by HGNC Official Full Name tripartite motif containing 9provided by HGNC Primary source HGNC:HGNC:16288 See related Ensembl:ENSG00000100505 MIM:606555; AllianceGenome:HGNC:16288 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF91; SPRING Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 15.3), gall bladder (RPKM 1.4) and 1 other tissue See more Orthologs mouse all
TRIML1, Official Symbol TRIML1provided by HGNC Official Full Name tripartite motif family like 1provided by HGNC Primary source HGNC:HGNC:26698 See related Ensembl:ENSG00000184108 AllianceGenome:HGNC:26698 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF209 Summary The protein encoded by this gene is a tripartite motif family protein with similarities to E3 ubiquitin-protein ligases. While the function of the encoded protein has not been determined, the orthologous protein in mouse has been shown to bind ubiquitin-specific protease 5 and is involved in the blastocyst development stage. [provided by RefSeq, Sep 2016] Expression Restricted expression toward testis (RPKM 5.0) See more Orthologs mouse all
TRIML2, Official Symbol TRIML2provided by HGNC Official Full Name tripartite motif family like 2provided by HGNC Primary source HGNC:HGNC:26378 See related Ensembl:ENSG00000179046 MIM:620480; AllianceGenome:HGNC:26378 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPRYD6 Summary This gene encodes a member of the tri-partite motif (TRIM) family of proteins. This protein may be regulated by the tumor suppressor p53 and may regulate p53 through the enhancement of p53 SUMOylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Biased expression in placenta (RPKM 2.0) and testis (RPKM 1.2) See more Orthologs mouse all
TRIO, Official Symbol TRIOprovided by HGNC Official Full Name trio Rho guanine nucleotide exchange factorprovided by HGNC Primary source HGNC:HGNC:12303 See related Ensembl:ENSG00000038382 MIM:601893; AllianceGenome:HGNC:12303 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as tgat; MEBAS; MRD44; MRD63; ARHGEF23 Summary This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in brain (RPKM 8.0), spleen (RPKM 6.0) and 25 other tissues See more Orthologs mouse all
TRIOBP, Official Symbol TRIOBPprovided by HGNC Official Full Name TRIO and F-actin binding proteinprovided by HGNC Primary source HGNC:HGNC:17009 See related Ensembl:ENSG00000100106 MIM:609761; AllianceGenome:HGNC:17009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TARA; TAP68; DFNB28; dJ37E16.4; HRIHFB2122 Summary This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008] Expression Ubiquitous expression in spleen (RPKM 8.0), placenta (RPKM 7.0) and 25 other tissues See more Orthologs mouse all
TRIP10, Official Symbol TRIP10provided by HGNC Official Full Name thyroid hormone receptor interactor 10provided by HGNC Primary source HGNC:HGNC:12304 See related Ensembl:ENSG00000125733 MIM:604504; AllianceGenome:HGNC:12304 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STP; CIP4; HSTP; STOT; TRIP-10 Summary Enables identical protein binding activity. Predicted to be involved in actin cytoskeleton organization; endocytosis; and signal transduction. Located in nucleoplasm. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 54.6), fat (RPKM 34.4) and 22 other tissues See more Orthologs mouse all
TRIP11, Official Symbol TRIP11provided by HGNC Official Full Name thyroid hormone receptor interactor 11provided by HGNC Primary source HGNC:HGNC:12305 See related Ensembl:ENSG00000100815 MIM:604505; AllianceGenome:HGNC:12305 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ODCD; ACG1A; CEV14; ODCD1; GMAP210; TRIP-11; TRIP230; GMAP-210 Summary This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.[provided by RefSeq, Mar 2010] Expression Ubiquitous expression in thyroid (RPKM 9.3), kidney (RPKM 6.5) and 25 other tissues See more Orthologs mouse all
TRIP12, Official Symbol TRIP12provided by HGNC Official Full Name thyroid hormone receptor interactor 12provided by HGNC Primary source HGNC:HGNC:12306 See related Ensembl:ENSG00000153827 MIM:604506; AllianceGenome:HGNC:12306 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ULF; MRD49; TRIPC; TRIP-12 Summary The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017] Expression Broad expression in testis (RPKM 48.5), thyroid (RPKM 17.6) and 24 other tissues See more Orthologs mouse all
TRIP13, Official Symbol TRIP13provided by HGNC Official Full Name thyroid hormone receptor interactor 13provided by HGNC Primary source HGNC:HGNC:12307 See related Ensembl:ENSG00000071539 MIM:604507; AllianceGenome:HGNC:12307 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MVA3; OOMD9; 16E1BP; OZEMA9 Summary This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009] Expression Biased expression in testis (RPKM 14.2), lymph node (RPKM 3.0) and 10 other tissues See more Orthologs mouse all