psui3905/ncbi_genes_summary huggingface dataset:
GAN, Official Symbol GANprovided by HGNC Official Full Name gigaxoninprovided by HGNC Primary source HGNC:HGNC:4137 See related Ensembl:ENSG00000261609 MIM:605379; AllianceGenome:HGNC:4137 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GIG; GAN1; KLHL16 Summary This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008] Expression Broad expression in skin (RPKM 5.8), esophagus (RPKM 2.0) and 23 other tissues See more Orthologs mouse all
GANAB, Official Symbol GANABprovided by HGNC Official Full Name glucosidase II alpha subunitprovided by HGNC Primary source HGNC:HGNC:4138 See related Ensembl:ENSG00000089597 MIM:104160; AllianceGenome:HGNC:4138 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2AN; GIIA; PKD3; GLUII; GIIalpha Summary This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in thyroid (RPKM 85.4), placenta (RPKM 75.3) and 25 other tissues See more Orthologs mouse all
GANC, Official Symbol GANCprovided by HGNC Official Full Name glucosidase alpha, neutral Cprovided by HGNC Primary source HGNC:HGNC:4139 See related Ensembl:ENSG00000214013 MIM:104180; AllianceGenome:HGNC:4139 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014] Expression Ubiquitous expression in lung (RPKM 6.2), testis (RPKM 3.4) and 25 other tissues See more Orthologs mouse all
GAP43, Official Symbol GAP43provided by HGNC Official Full Name growth associated protein 43provided by HGNC Primary source HGNC:HGNC:4140 See related Ensembl:ENSG00000172020 MIM:162060; AllianceGenome:HGNC:4140 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B-50; PP46; GAP-43 Summary The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 55.1) and appendix (RPKM 1.7) See more Orthologs mouse all
GAPDH, Official Symbol GAPDHprovided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:4141 See related Ensembl:ENSG00000111640 MIM:138400; AllianceGenome:HGNC:4141 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G3PD; GAPD; HEL-S-162eP Summary This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Ubiquitous expression in bone marrow (RPKM 1203.9), heart (RPKM 1083.8) and 24 other tissues See more Orthologs mouse all
GAPDHP15, Official Symbol GAPDHP15provided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenase pseudogene 15provided by HGNC Primary source HGNC:HGNC:13950 See related Ensembl:ENSG00000214563 AllianceGenome:HGNC:13950 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDP15; GAPDH-Lp; b55C20.4
GAPDHP16, Official Symbol GAPDHP16provided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenase pseudogene 16provided by HGNC Primary source HGNC:HGNC:23768 See related Ensembl:ENSG00000225502 AllianceGenome:HGNC:23768 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDP16
GAPDHP19, Official Symbol GAPDHP19provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 19provided by HGNC Primary source HGNC:HGNC:23947 See related AllianceGenome:HGNC:23947 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP21, Official Symbol GAPDHP21provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 21provided by HGNC Primary source HGNC:HGNC:37773 See related AllianceGenome:HGNC:37773 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP22, Official Symbol GAPDHP22provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 22provided by HGNC Primary source HGNC:HGNC:37774 See related Ensembl:ENSG00000234005 AllianceGenome:HGNC:37774 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP23, Official Symbol GAPDHP23provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 23provided by HGNC Primary source HGNC:HGNC:37775 See related AllianceGenome:HGNC:37775 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP27, Official Symbol GAPDHP27provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 27provided by HGNC Primary source HGNC:HGNC:37779 See related AllianceGenome:HGNC:37779 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP31, Official Symbol GAPDHP31provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 31provided by HGNC Primary source HGNC:HGNC:37783 See related AllianceGenome:HGNC:37783 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP32, Official Symbol GAPDHP32provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 32provided by HGNC Primary source HGNC:HGNC:37784 See related AllianceGenome:HGNC:37784 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP34, Official Symbol GAPDHP34provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 34provided by HGNC Primary source HGNC:HGNC:37786 See related Ensembl:ENSG00000235306 AllianceGenome:HGNC:37786 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP36, Official Symbol GAPDHP36provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 36provided by HGNC Primary source HGNC:HGNC:37790 See related Ensembl:ENSG00000213158 AllianceGenome:HGNC:37790 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP41, Official Symbol GAPDHP41provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 41provided by HGNC Primary source HGNC:HGNC:37798 See related Ensembl:ENSG00000277172 AllianceGenome:HGNC:37798 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP42, Official Symbol GAPDHP42provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 42provided by HGNC Primary source HGNC:HGNC:37799 See related AllianceGenome:HGNC:37799 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP46, Official Symbol GAPDHP46provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 46provided by HGNC Primary source HGNC:HGNC:37804 See related Ensembl:ENSG00000224678 AllianceGenome:HGNC:37804 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP47, Official Symbol GAPDHP47provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 47provided by HGNC Primary source HGNC:HGNC:37803 See related Ensembl:ENSG00000243033 AllianceGenome:HGNC:37803 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP48, Official Symbol GAPDHP48provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 48provided by HGNC Primary source HGNC:HGNC:37805 See related AllianceGenome:HGNC:37805 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP49, Official Symbol GAPDHP49provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 49provided by HGNC Primary source HGNC:HGNC:38555 See related Ensembl:ENSG00000234285 AllianceGenome:HGNC:38555 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP50, Official Symbol GAPDHP50provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 50provided by HGNC Primary source HGNC:HGNC:38556 See related Ensembl:ENSG00000241861 AllianceGenome:HGNC:38556 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP51, Official Symbol GAPDHP51provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 51provided by HGNC Primary source HGNC:HGNC:38557 See related Ensembl:ENSG00000236973 AllianceGenome:HGNC:38557 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP52, Official Symbol GAPDHP52provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 52provided by HGNC Primary source HGNC:HGNC:38558 See related Ensembl:ENSG00000235076 AllianceGenome:HGNC:38558 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP53, Official Symbol GAPDHP53provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 53provided by HGNC Primary source HGNC:HGNC:38559 See related Ensembl:ENSG00000234069 AllianceGenome:HGNC:38559 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP54, Official Symbol GAPDHP54provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 54provided by HGNC Primary source HGNC:HGNC:38560 See related Ensembl:ENSG00000226769 AllianceGenome:HGNC:38560 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP55, Official Symbol GAPDHP55provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 55provided by HGNC Primary source HGNC:HGNC:38561 See related Ensembl:ENSG00000224055 AllianceGenome:HGNC:38561 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP56, Official Symbol GAPDHP56provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 56provided by HGNC Primary source HGNC:HGNC:38562 See related Ensembl:ENSG00000249018 AllianceGenome:HGNC:38562 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP57, Official Symbol GAPDHP57provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 57provided by HGNC Primary source HGNC:HGNC:38563 See related Ensembl:ENSG00000236167 AllianceGenome:HGNC:38563 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHP58, Official Symbol GAPDHP58provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 58provided by HGNC Primary source HGNC:HGNC:4142 See related Ensembl:ENSG00000229570 AllianceGenome:HGNC:4142 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL1; GAPDHL1
GAPDHP62, Official Symbol GAPDHP62provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 62provided by HGNC Primary source HGNC:HGNC:4156 See related Ensembl:ENSG00000251013 AllianceGenome:HGNC:4156 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL7; GAPDHL7
GAPDHP63, Official Symbol GAPDHP63provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 63provided by HGNC Primary source HGNC:HGNC:4157 See related AllianceGenome:HGNC:4157 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL8; GAPDHL8
GAPDHP66, Official Symbol GAPDHP66provided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenase pseudogene 66provided by HGNC Primary source HGNC:HGNC:4144 See related AllianceGenome:HGNC:4144 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL11; GAPDHL11
GAPDHP69, Official Symbol GAPDHP69provided by HGNC Official Full Name glyceraldehyde 3 phosphate dehydrogenase pseudogene 69provided by HGNC Primary source HGNC:HGNC:4147 See related AllianceGenome:HGNC:4147 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL14; GAPDHL14
GAPDHP71, Official Symbol GAPDHP71provided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenase pseudogene 71provided by HGNC Primary source HGNC:HGNC:4149 See related AllianceGenome:HGNC:4149 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPDL16; GAPDHL16
GAPDHP77, Official Symbol GAPDHP77provided by HGNC Official Full Name GAPDH pseudogene 77provided by HGNC Primary source HGNC:HGNC:55049 See related Ensembl:ENSG00000215000 AllianceGenome:HGNC:55049 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAPDHS, Official Symbol GAPDHSprovided by HGNC Official Full Name glyceraldehyde-3-phosphate dehydrogenase, spermatogenicprovided by HGNC Primary source HGNC:HGNC:24864 See related Ensembl:ENSG00000105679 MIM:609169; AllianceGenome:HGNC:24864 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAPD2; GAPDS; HSD-35; GAPDH-2; HEL-S-278 Summary This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 87.7) and thyroid (RPKM 2.9) See more Orthologs mouse all
GAPT, Official Symbol GAPTprovided by HGNC Official Full Name GRB2 binding adaptor protein, transmembraneprovided by HGNC Primary source HGNC:HGNC:26588 See related Ensembl:ENSG00000175857 MIM:620440; AllianceGenome:HGNC:26588 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C5orf29 Summary Predicted to be involved in B cell homeostasis and B cell proliferation involved in immune response. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in appendix (RPKM 12.0), lymph node (RPKM 8.4) and 11 other tissues See more Orthologs mouse all
GAPVD1, Official Symbol GAPVD1provided by HGNC Official Full Name GTPase activating protein and VPS9 domains 1provided by HGNC Primary source HGNC:HGNC:23375 See related Ensembl:ENSG00000165219 MIM:611714; AllianceGenome:HGNC:23375 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAP6; GAPEX5; GAPex-5 Summary Enables GTPase activating protein binding activity and guanyl-nucleotide exchange factor activity. Involved in regulation of protein transport. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 13.1), thyroid (RPKM 9.8) and 25 other tissues See more Orthologs mouse all
GAR1, Official Symbol GAR1provided by HGNC Official Full Name GAR1 ribonucleoproteinprovided by HGNC Primary source HGNC:HGNC:14264 See related Ensembl:ENSG00000109534 MIM:606468; AllianceGenome:HGNC:14264 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOLA1 Summary This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 10.2), bone marrow (RPKM 9.6) and 25 other tissues See more Orthologs mouse all
GAREM2, Official Symbol GAREM2provided by HGNC Official Full Name GRB2 associated regulator of MAPK1 subtype 2provided by HGNC Primary source HGNC:HGNC:27172 See related Ensembl:ENSG00000157833 MIM:617999; AllianceGenome:HGNC:27172 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM59B; GAREML Expression Broad expression in brain (RPKM 5.7), testis (RPKM 1.0) and 17 other tissues See more Orthologs mouse all
GARNL3, Official Symbol GARNL3provided by HGNC Official Full Name GTPase activating Rap/RanGAP domain like 3provided by HGNC Primary source HGNC:HGNC:25425 See related Ensembl:ENSG00000136895 AllianceGenome:HGNC:25425 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as bA356B19.1 Summary Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 5.0), heart (RPKM 3.2) and 23 other tissues See more Orthologs mouse all
GARS1P1, Official Symbol GARS1P1provided by HGNC Official Full Name glycyl-tRNA synthetase 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:50480 See related Ensembl:ENSG00000262135 AllianceGenome:HGNC:50480 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GARSP1
GART, Official Symbol GARTprovided by HGNC Official Full Name phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetaseprovided by HGNC Primary source HGNC:HGNC:4163 See related Ensembl:ENSG00000159131 MIM:138440; AllianceGenome:HGNC:4163 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIRS; GARS; PAIS; PGFT; PRGS; GARTF Summary The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 13.5), lymph node (RPKM 11.6) and 25 other tissues See more Orthologs mouse all
GAS1, Official Symbol GAS1provided by HGNC Official Full Name growth arrest specific 1provided by HGNC Primary source HGNC:HGNC:4165 See related Ensembl:ENSG00000180447 MIM:139185; AllianceGenome:HGNC:4165 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008] Orthologs mouse all
GAS1RR, Official Symbol GAS1RRprovided by HGNC Official Full Name GAS1 adjacent regulatory RNAprovided by HGNC Primary source HGNC:HGNC:52261 See related Ensembl:ENSG00000226237 AllianceGenome:HGNC:52261 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LncRNA-Hh Expression Broad expression in skin (RPKM 1.0), ovary (RPKM 0.9) and 21 other tissues See more
GAS2, Official Symbol GAS2provided by HGNC Official Full Name growth arrest specific 2provided by HGNC Primary source HGNC:HGNC:4167 See related Ensembl:ENSG00000148935 MIM:602835; AllianceGenome:HGNC:4167 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAS-2 Summary The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017] Expression Broad expression in liver (RPKM 2.8), kidney (RPKM 0.9) and 21 other tissues See more Orthologs mouse all
GAS2L1, Official Symbol GAS2L1provided by HGNC Official Full Name growth arrest specific 2 like 1provided by HGNC Primary source HGNC:HGNC:16955 See related Ensembl:ENSG00000185340 MIM:602128; AllianceGenome:HGNC:16955 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAR22 Summary This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. This protein localizes to the proximal end of mature centrioles and links centrosomes to both microtubules and actin. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2018] Expression Broad expression in testis (RPKM 11.4), fat (RPKM 8.4) and 25 other tissues See more Orthologs mouse all
GAS2L1P2, Official Symbol GAS2L1P2provided by HGNC Official Full Name growth arrest specific 2 like 1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:27986 See related Ensembl:ENSG00000228376 AllianceGenome:HGNC:27986 Gene type pseudo RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 1.1) See more
GAS2L2, Official Symbol GAS2L2provided by HGNC Official Full Name growth arrest specific 2 like 2provided by HGNC Primary source HGNC:HGNC:24846 See related Ensembl:ENSG00000270765 MIM:611398; AllianceGenome:HGNC:24846 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAR17; CILD41 Summary The protein encoded by this gene appears to crosslink microtubules and microfilaments and may be part of the cytoskeleton. This gene is mainly expressed in skeletal muscle. [provided by RefSeq, Jul 2011] Expression Biased expression in lung (RPKM 1.4), fat (RPKM 0.6) and 5 other tissues See more Orthologs mouse all
GAS2L3, Official Symbol GAS2L3provided by HGNC Official Full Name growth arrest specific 2 like 3provided by HGNC Primary source HGNC:HGNC:27475 See related Ensembl:ENSG00000139354 MIM:617224; AllianceGenome:HGNC:27475 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2L3 Summary Enables actin binding activity and microtubule binding activity. Involved in actin cytoskeleton organization and microtubule cytoskeleton organization. Located in actin cytoskeleton and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in gall bladder (RPKM 2.2), colon (RPKM 1.8) and 23 other tissues See more Orthologs mouse all
GAS5, Official Symbol GAS5provided by HGNC Official Full Name growth arrest specific 5provided by HGNC Primary source HGNC:HGNC:16355 See related Ensembl:ENSG00000234741 MIM:608280; AllianceGenome:HGNC:16355 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SNHG2; NCRNA00030 Summary This gene produces a spliced long non-coding RNA and is a member of the 5' terminal oligo-pyrimidine class of genes. It is a small nucleolar RNA host gene, containing multiple C/D box snoRNA genes in its introns. Part of the secondary RNA structure of the encoded transcript mimics glucocorticoid response element (GRE) which means it can bind to the DNA binding domain of the glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1). This action blocks the glucocorticoid receptor from being activated and thereby stops it from regulating the transcription of its target genes. This transcript is also thought to regulate the transcriptional activity of other receptors, such as androgen, progesterone and mineralocorticoid receptors, that can bind to its GRE mimic region. Multiple functions have been associated with this transcript, including cellular growth arrest and apoptosis. It has also been identified as a potential tumor suppressor, with its down-regulation associated with cancer in multiple different tissues. [provided by RefSeq, Mar 2015] Expression Ubiquitous expression in ovary (RPKM 307.5), thyroid (RPKM 113.4) and 24 other tissues See more Orthologs mouse all
GAS5-AS1, Official Symbol GAS5-AS1provided by HGNC Official Full Name GAS5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44119 See related AllianceGenome:HGNC:44119 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
GAS6, Official Symbol GAS6provided by HGNC Official Full Name growth arrest specific 6provided by HGNC Primary source HGNC:HGNC:4168 See related Ensembl:ENSG00000183087 MIM:600441; AllianceGenome:HGNC:4168 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AXSF; AXLLG Summary This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014] Expression Ubiquitous expression in lung (RPKM 64.9), endometrium (RPKM 57.7) and 24 other tissues See more Orthologs mouse all
GAS6-DT, Official Symbol GAS6-DTprovided by HGNC Official Full Name GAS6 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:43694 See related Ensembl:ENSG00000272695 AllianceGenome:HGNC:43694 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAS6-AS2 Expression Broad expression in endometrium (RPKM 2.3), urinary bladder (RPKM 1.8) and 23 other tissues See more
GAS7, Official Symbol GAS7provided by HGNC Official Full Name growth arrest specific 7provided by HGNC Primary source HGNC:HGNC:4169 See related Ensembl:ENSG00000007237 MIM:603127; AllianceGenome:HGNC:4169 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 53.9), skin (RPKM 13.3) and 17 other tissues See more Orthologs mouse all
GAS8, Official Symbol GAS8provided by HGNC Official Full Name growth arrest specific 8provided by HGNC Primary source HGNC:HGNC:4166 See related Ensembl:ENSG00000141013 MIM:605178; AllianceGenome:HGNC:4166 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRC4; GAS11; CILD33 Summary This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] Expression Ubiquitous expression in testis (RPKM 6.8), thyroid (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
GAS8-AS1, Official Symbol GAS8-AS1provided by HGNC Official Full Name GAS8 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:1197 See related Ensembl:ENSG00000221819 MIM:605179; AllianceGenome:HGNC:1197 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C16orf3 Summary This gene encodes a long non-coding RNA (lncRNA) that may function as a tumor suppressor. Mutations in this gene have been identified in human papillary thyroid carcinoma (PTC) patients that abrogate the ability of encoded lncRNA to inhibit cancer cell growth. [provided by RefSeq, May 2017]
GASK1A, Official Symbol GASK1Aprovided by HGNC Official Full Name golgi associated kinase 1Aprovided by HGNC Primary source HGNC:HGNC:24485 See related Ensembl:ENSG00000144649 MIM:620413; AllianceGenome:HGNC:24485 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C3orf41; FAM198A Summary Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Note: LOC26172 (GeneID: 26172) was previously annotated as C3orf41, and a chimeric/readthrough mRNA that contained part of this gene, GeneID: 729085 and GeneID: 26172 was associated with the locus. The two genes are now represented by separate entries, LOC26172 (GeneID: 26172) and C3orf41 (GeneID: 729085). [13 Feb 2013] Expression Broad expression in gall bladder (RPKM 4.2), endometrium (RPKM 3.5) and 24 other tissues See more Orthologs mouse all
GASK1B, Official Symbol GASK1Bprovided by HGNC Official Full Name golgi associated kinase 1Bprovided by HGNC Primary source HGNC:HGNC:25312 See related Ensembl:ENSG00000164125 AllianceGenome:HGNC:25312 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENED; AD021; AD036; C4orf18; FAM198B Summary Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in adrenal (RPKM 128.3), ovary (RPKM 68.9) and 17 other tissues See more Orthologs mouse all
GAST, Official Symbol GASTprovided by HGNC Official Full Name gastrinprovided by HGNC Primary source HGNC:HGNC:4164 See related Ensembl:ENSG00000184502 MIM:137250; AllianceGenome:HGNC:4164 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAS Summary Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008] Expression Restricted expression toward stomach (RPKM 4383.1) See more Orthologs mouse all
GATA1, Official Symbol GATA1provided by HGNC Official Full Name GATA binding protein 1provided by HGNC Primary source HGNC:HGNC:4170 See related Ensembl:ENSG00000102145 MIM:305371; AllianceGenome:HGNC:4170 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1; HAEADA Summary This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 18.9) and placenta (RPKM 0.5) See more Orthologs mouse all
GATA2, Official Symbol GATA2provided by HGNC Official Full Name GATA binding protein 2provided by HGNC Primary source HGNC:HGNC:4171 See related Ensembl:ENSG00000179348 MIM:137295; AllianceGenome:HGNC:4171 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DCML; IMD21; NFE1B; MONOMAC Summary This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] Expression Broad expression in prostate (RPKM 28.7), endometrium (RPKM 17.9) and 16 other tissues See more Orthologs mouse all
GATA3, Official Symbol GATA3provided by HGNC Official Full Name GATA binding protein 3provided by HGNC Primary source HGNC:HGNC:4172 See related Ensembl:ENSG00000107485 MIM:131320; AllianceGenome:HGNC:4172 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HDR; HDRS Summary This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] Expression Biased expression in skin (RPKM 54.6), urinary bladder (RPKM 20.0) and 7 other tissues See more Orthologs mouse all
GATA3-AS1, Official Symbol GATA3-AS1provided by HGNC Official Full Name GATA3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:33786 See related Ensembl:ENSG00000197308 AllianceGenome:HGNC:33786 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in kidney (RPKM 1.7), urinary bladder (RPKM 0.9) and 4 other tissues See more
GATA4, Official Symbol GATA4provided by HGNC Official Full Name GATA binding protein 4provided by HGNC Primary source HGNC:HGNC:4173 See related Ensembl:ENSG00000136574 MIM:600576; AllianceGenome:HGNC:4173 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TOF; ASD2; VSD1; TACHD Summary This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Expression Biased expression in ovary (RPKM 23.7), duodenum (RPKM 16.4) and 8 other tissues See more Orthologs mouse all
GATA5, Official Symbol GATA5provided by HGNC Official Full Name GATA binding protein 5provided by HGNC Primary source HGNC:HGNC:15802 See related Ensembl:ENSG00000130700 MIM:611496; AllianceGenome:HGNC:15802 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHTD5; GATAS; bB379O24.1 Summary The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008] Expression Biased expression in duodenum (RPKM 4.8), small intestine (RPKM 4.6) and 13 other tissues See more Orthologs mouse all