psui3905/ncbi_genes_summary huggingface dataset:
WDR17, Official Symbol WDR17provided by HGNC Official Full Name WD repeat domain 17provided by HGNC Primary source HGNC:HGNC:16661 See related Ensembl:ENSG00000150627 MIM:609005; AllianceGenome:HGNC:16661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2009] Expression Biased expression in brain (RPKM 5.2), thyroid (RPKM 2.5) and 12 other tissues See more Orthologs mouse all
WDR18, Official Symbol WDR18provided by HGNC Official Full Name WD repeat domain 18provided by HGNC Primary source HGNC:HGNC:17956 See related Ensembl:ENSG00000065268 MIM:620291; AllianceGenome:HGNC:17956 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Ipi3; R32184_1 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 9.8), colon (RPKM 5.8) and 25 other tissues See more Orthologs mouse all
WDR19, Official Symbol WDR19provided by HGNC Official Full Name WD repeat domain 19provided by HGNC Primary source HGNC:HGNC:18340 See related Ensembl:ENSG00000157796 MIM:608151; AllianceGenome:HGNC:18340 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATD5; CED4; DYF-2; FAP66; ORF26; Oseg6; PWDMP; SRTD5; CFAP66; IFT144; NPHP13; SPGF72 Summary The protein encoded by this gene is a member of the WD (tryptophan-aspartic acid) repeat family, which is a large family of structurally-related proteins known to participate in a wide range of cellular processes. Each WD repeat typically contains about 40 amino acids that are usually bracketed by glycine-histidine and tryptophan-aspartic acid (WD) dipeptides. This protein contains six WD repeats, three transmembrane domains, and a clathrin heavy-chain repeat. Mutations in this gene have been described in individuals with a wide range of disorders affecting function of the cilium. These disorders are known as ciliopathies, and include Jeune syndrome, Sensenbrenner syndromes, Senior-Loken syndrome, combined or isolated nephronophthisis (NPHP), and retinitis pigmentosa (RP). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] Expression Broad expression in thyroid (RPKM 9.7), testis (RPKM 8.9) and 25 other tissues See more Orthologs mouse all
WDR20, Official Symbol WDR20provided by HGNC Official Full Name WD repeat domain 20provided by HGNC Primary source HGNC:HGNC:19667 See related Ensembl:ENSG00000140153 MIM:617741; AllianceGenome:HGNC:19667 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DMR; Bun107 Summary This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in testis (RPKM 5.3), thyroid (RPKM 3.2) and 25 other tissues See more Orthologs mouse all
WDR24, Official Symbol WDR24provided by HGNC Official Full Name WD repeat domain 24provided by HGNC Primary source HGNC:HGNC:20852 See related Ensembl:ENSG00000127580 MIM:620307; AllianceGenome:HGNC:20852 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JFP7; C16orf21 Summary Involved in cellular response to amino acid starvation; positive regulation of TOR signaling; and regulation of autophagy. Located in cytosol and lysosomal membrane. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.5), spleen (RPKM 3.4) and 25 other tissues See more Orthologs mouse all
WDR25, Official Symbol WDR25provided by HGNC Official Full Name WD repeat domain 25provided by HGNC Primary source HGNC:HGNC:21064 See related Ensembl:ENSG00000176473 MIM:618059; AllianceGenome:HGNC:21064 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf67 Summary This gene encodes a protein containing 7 WD repeats. WD repeats are approximately 30 to 40-amino acid domains containing several conserved residues, typically having a Tryptophan-Aspartic acid dipeptide (WD) at the C-terminal end. WD domains are involved in protein-protein interactions in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in thyroid (RPKM 3.8), testis (RPKM 2.7) and 25 other tissues See more Orthologs mouse all
WDR26, Official Symbol WDR26provided by HGNC Official Full Name WD repeat domain 26provided by HGNC Primary source HGNC:HGNC:21208 See related Ensembl:ENSG00000162923 MIM:617424; AllianceGenome:HGNC:21208 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDW2; GID7; MIP2; SKDEAS Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 30.1), esophagus (RPKM 28.6) and 25 other tissues See more Orthologs mouse all
WDR27, Official Symbol WDR27provided by HGNC Official Full Name WD repeat domain 27provided by HGNC Primary source HGNC:HGNC:21248 See related Ensembl:ENSG00000184465 AllianceGenome:HGNC:21248 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein with multiple WD repeats. Proteins with these repeats may form scaffolds for protein-protein interaction and play key roles in cell signalling. Alternative splicing results in multiple transcript variants, but the full-length structure of some of these variants cannot be determined. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in testis (RPKM 1.4), ovary (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
WDR3, Official Symbol WDR3provided by HGNC Official Full Name WD repeat domain 3provided by HGNC Primary source HGNC:HGNC:12755 See related Ensembl:ENSG00000065183 MIM:604737; AllianceGenome:HGNC:12755 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIP2; UTP12 Summary This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 13.4), appendix (RPKM 7.9) and 25 other tissues See more Orthologs mouse all
WDR31, Official Symbol WDR31provided by HGNC Official Full Name WD repeat domain 31provided by HGNC Primary source HGNC:HGNC:21421 See related Ensembl:ENSG00000148225 AllianceGenome:HGNC:21421 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 3.6), thyroid (RPKM 2.8) and 24 other tissues See more Orthologs mouse all
WDR33, Official Symbol WDR33provided by HGNC Official Full Name WD repeat domain 33provided by HGNC Primary source HGNC:HGNC:25651 See related Ensembl:ENSG00000136709 MIM:618082; AllianceGenome:HGNC:25651 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET14; WDC146 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 5.8), lymph node (RPKM 4.9) and 25 other tissues See more Orthologs mouse all
WDR35, Official Symbol WDR35provided by HGNC Official Full Name WD repeat domain 35provided by HGNC Primary source HGNC:HGNC:29250 See related Ensembl:ENSG00000118965 MIM:613602; AllianceGenome:HGNC:29250 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CED2; IFTA1; SRTD7; FAP118; IFT121; CFAP118 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010] Expression Broad expression in testis (RPKM 8.4), thyroid (RPKM 5.2) and 24 other tissues See more Orthologs mouse all
WDR36, Official Symbol WDR36provided by HGNC Official Full Name WD repeat domain 36provided by HGNC Primary source HGNC:HGNC:30696 See related Ensembl:ENSG00000134987 MIM:609669; AllianceGenome:HGNC:30696 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLC1G; UTP21; TAWDRP; TA-WDRP Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 7.1), lymph node (RPKM 6.5) and 25 other tissues See more Orthologs mouse all
WDR37, Official Symbol WDR37provided by HGNC Official Full Name WD repeat domain 37provided by HGNC Primary source HGNC:HGNC:31406 See related Ensembl:ENSG00000047056 MIM:618586; AllianceGenome:HGNC:31406 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOCGUS Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 11.4), spleen (RPKM 8.6) and 25 other tissues See more Orthologs mouse all
WDR38, Official Symbol WDR38provided by HGNC Official Full Name WD repeat domain 38provided by HGNC Primary source HGNC:HGNC:23745 See related Ensembl:ENSG00000136918 AllianceGenome:HGNC:23745 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to act upstream of or within hematopoietic progenitor cell differentiation. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lung (RPKM 2.9), testis (RPKM 2.5) and 7 other tissues See more Orthologs mouse all
WDR4, Official Symbol WDR4provided by HGNC Official Full Name WD repeat domain 4provided by HGNC Primary source HGNC:HGNC:12756 See related Ensembl:ENSG00000160193 MIM:605924; AllianceGenome:HGNC:12756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hWH; Wuho; MIGSB; TRM82; GAMOS6; TRMT82 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] Expression Ubiquitous expression in lymph node (RPKM 3.3), appendix (RPKM 3.2) and 25 other tissues See more Orthologs mouse all
WDR41, Official Symbol WDR41provided by HGNC Official Full Name WD repeat domain 41provided by HGNC Primary source HGNC:HGNC:25601 See related Ensembl:ENSG00000164253 MIM:617502; AllianceGenome:HGNC:25601 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MSTP048 Summary Contributes to guanyl-nucleotide exchange factor activity. Involved in regulation of autophagy. Located in cytoplasm. Part of guanyl-nucleotide exchange factor complex. Colocalizes with Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 15.6), brain (RPKM 8.1) and 25 other tissues See more Orthologs mouse all
WDR43, Official Symbol WDR43provided by HGNC Official Full Name WD repeat domain 43provided by HGNC Primary source HGNC:HGNC:28945 See related Ensembl:ENSG00000163811 MIM:616195; AllianceGenome:HGNC:28945 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UTP5; NET12 Summary Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in fibrillar center. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 11.4), appendix (RPKM 11.1) and 25 other tissues See more Orthologs mouse all
WDR44, Official Symbol WDR44provided by HGNC Official Full Name WD repeat domain 44provided by HGNC Primary source HGNC:HGNC:30512 See related Ensembl:ENSG00000131725 MIM:301070; AllianceGenome:HGNC:30512 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RPH11; SYM-4; RAB11BP Summary This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Expression Ubiquitous expression in gall bladder (RPKM 7.8), testis (RPKM 7.1) and 25 other tissues See more Orthologs mouse all
WDR45, Official Symbol WDR45provided by HGNC Official Full Name WD repeat domain 45provided by HGNC Primary source HGNC:HGNC:28912 See related Ensembl:ENSG00000196998 MIM:300526; AllianceGenome:HGNC:28912 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JM5; NBIA4; NBIA5; WDRX1; WIPI4; WIPI-4 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 16.7), adrenal (RPKM 15.8) and 25 other tissues See more Orthologs mouse all
WDR45B, Official Symbol WDR45Bprovided by HGNC Official Full Name WD repeat domain 45Bprovided by HGNC Primary source HGNC:HGNC:25072 See related Ensembl:ENSG00000141580 MIM:609226; AllianceGenome:HGNC:25072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WIPI3; WDR45L; WIPI-3; NEDSBAS Summary This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with phospholipids. The human genome contains several pseudogenes of this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 30.3), esophagus (RPKM 20.3) and 25 other tissues See more Orthologs mouse all
WDR45P1, Official Symbol WDR45P1provided by HGNC Official Full Name WD repeat domain 45 pseudogene 1provided by HGNC Primary source HGNC:HGNC:52406 See related AllianceGenome:HGNC:52406 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WDR45P
WDR46, Official Symbol WDR46provided by HGNC Official Full Name WD repeat domain 46provided by HGNC Primary source HGNC:HGNC:13923 See related Ensembl:ENSG00000227057 MIM:611440; AllianceGenome:HGNC:13923 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UTP7; BING4; FP221; C6orf11 Summary Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 10.6), testis (RPKM 10.3) and 25 other tissues See more Orthologs mouse all
WDR47, Official Symbol WDR47provided by HGNC Official Full Name WD repeat domain 47provided by HGNC Primary source HGNC:HGNC:29141 See related Ensembl:ENSG00000085433 MIM:615734; AllianceGenome:HGNC:29141 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 29.8), testis (RPKM 15.2) and 22 other tissues See more Orthologs mouse all
WDR48, Official Symbol WDR48provided by HGNC Official Full Name WD repeat domain 48provided by HGNC Primary source HGNC:HGNC:30914 See related Ensembl:ENSG00000114742 MIM:612167; AllianceGenome:HGNC:30914 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P80; UAF1; Bun62; SPG60 Summary The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated FANCD2. FANCD2 is ubiquitinated in response to DNA damage. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in testis (RPKM 33.3), bone marrow (RPKM 19.8) and 25 other tissues See more Orthologs mouse all
WDR49, Official Symbol WDR49provided by HGNC Official Full Name WD repeat domain 49provided by HGNC Primary source HGNC:HGNC:26587 See related Ensembl:ENSG00000174776 AllianceGenome:HGNC:26587 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the WD repeat protein family with nine WD repeats. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Biased expression in brain (RPKM 1.0), small intestine (RPKM 1.0) and 13 other tissues See more Orthologs mouse all
WDR4P1, Official Symbol WDR4P1provided by HGNC Official Full Name WDR4 pseudogene 1provided by HGNC Primary source HGNC:HGNC:55134 See related Ensembl:ENSG00000271158 AllianceGenome:HGNC:55134 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
WDR5, Official Symbol WDR5provided by HGNC Official Full Name WD repeat domain 5provided by HGNC Primary source HGNC:HGNC:12757 See related Ensembl:ENSG00000196363 MIM:609012; AllianceGenome:HGNC:12757 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIG3; SWD3; BIG-3; CFAP89 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 24.2), skin (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
WDR53, Official Symbol WDR53provided by HGNC Official Full Name WD repeat domain 53provided by HGNC Primary source HGNC:HGNC:28786 See related Ensembl:ENSG00000185798 MIM:615110; AllianceGenome:HGNC:28786 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein containing WD domains. The function of this gene is unknown. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 24.6), lymph node (RPKM 4.3) and 23 other tissues See more Orthologs mouse all
WDR54, Official Symbol WDR54provided by HGNC Official Full Name WD repeat domain 54provided by HGNC Primary source HGNC:HGNC:25770 See related Ensembl:ENSG00000005448 AllianceGenome:HGNC:25770 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables protein homodimerization activity. Involved in negative regulation of receptor internalization; regulation of MAPK cascade; and regulation of epidermal growth factor receptor signaling pathway. Located in vesicle. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 18.8), lung (RPKM 6.6) and 23 other tissues See more Orthologs mouse all
WDR55, Official Symbol WDR55provided by HGNC Official Full Name WD repeat domain 55provided by HGNC Primary source HGNC:HGNC:25971 See related Ensembl:ENSG00000120314 AllianceGenome:HGNC:25971 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in rRNA processing. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 5.7), colon (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
WDR59, Official Symbol WDR59provided by HGNC Official Full Name WD repeat domain 59provided by HGNC Primary source HGNC:HGNC:25706 See related Ensembl:ENSG00000103091 MIM:617418; AllianceGenome:HGNC:25706 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDW12; FP977; p90-120 Summary Involved in cellular response to amino acid starvation and positive regulation of TOR signaling. Located in lysosomal membrane. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 11.4), thyroid (RPKM 10.4) and 25 other tissues See more Orthologs mouse all
WDR5B, Official Symbol WDR5Bprovided by HGNC Official Full Name WD repeat domain 5Bprovided by HGNC Primary source HGNC:HGNC:17826 See related Ensembl:ENSG00000196981 AllianceGenome:HGNC:17826 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This intronless gene encodes a protein containing several WD40 repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, including a trp-asp at the C-terminal end. The encoded protein may mediate protein-protein interactions. [provided by RefSeq, Jul 2008] Orthologs mouse all
WDR5B-DT, Official Symbol WDR5B-DTprovided by HGNC Official Full Name WDR5B divergent transcriptprovided by HGNC Primary source HGNC:HGNC:55192 See related Ensembl:ENSG00000272758 AllianceGenome:HGNC:55192 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
WDR6, Official Symbol WDR6provided by HGNC Official Full Name WD repeat domain 6provided by HGNC Primary source HGNC:HGNC:12758 See related Ensembl:ENSG00000178252 MIM:606031; AllianceGenome:HGNC:12758 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Trm734 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in ovary (RPKM 54.4), endometrium (RPKM 45.4) and 25 other tissues See more Orthologs mouse all
WDR62, Official Symbol WDR62provided by HGNC Official Full Name WD repeat domain 62provided by HGNC Primary source HGNC:HGNC:24502 See related Ensembl:ENSG00000075702 MIM:613583; AllianceGenome:HGNC:24502 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCPH2; C19orf14 Summary This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] Expression Biased expression in testis (RPKM 39.3), bone marrow (RPKM 4.7) and 1 other tissue See more Orthologs mouse all
WDR64, Official Symbol WDR64provided by HGNC Official Full Name WD repeat domain 64provided by HGNC Primary source HGNC:HGNC:26570 See related Ensembl:ENSG00000162843 AllianceGenome:HGNC:26570 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 1.6) and placenta (RPKM 0.1) See more Orthologs mouse all
WDR7, Official Symbol WDR7provided by HGNC Official Full Name WD repeat domain 7provided by HGNC Primary source HGNC:HGNC:13490 See related Ensembl:ENSG00000091157 MIM:613473; AllianceGenome:HGNC:13490 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAG Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 12.4), thyroid (RPKM 5.9) and 24 other tissues See more Orthologs mouse all
WDR7-OT1, Official Symbol WDR7-OT1provided by HGNC Official Full Name WDR7 overlapping transcript 1provided by HGNC Primary source HGNC:HGNC:45131 See related AllianceGenome:HGNC:45131 Gene type ncRNA RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WDR7-UA1; WDR7-UT1 Expression Biased expression in testis (RPKM 1.0) and prostate (RPKM 0.1) See more
WDR70, Official Symbol WDR70provided by HGNC Official Full Name WD repeat domain 70provided by HGNC Primary source HGNC:HGNC:25495 See related Ensembl:ENSG00000082068 MIM:617233; AllianceGenome:HGNC:25495 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables enzyme binding activity. Predicted to be involved in regulation of DNA double-strand break processing and regulation of histone H2B conserved C-terminal lysine ubiquitination. Predicted to be active in nucleus and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 8.3), testis (RPKM 7.9) and 25 other tissues See more Orthologs mouse all
WDR72, Official Symbol WDR72provided by HGNC Official Full Name WD repeat domain 72provided by HGNC Primary source HGNC:HGNC:26790 See related Ensembl:ENSG00000166415 MIM:613214; AllianceGenome:HGNC:26790 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AI2A3 Summary This gene encodes a protein with eight WD-40 repeats. Mutations in this gene have been associated with amelogenesis imperfecta hypomaturation type 2A3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] Expression Biased expression in kidney (RPKM 35.1), thyroid (RPKM 25.6) and 3 other tissues See more Orthologs mouse all
WDR73, Official Symbol WDR73provided by HGNC Official Full Name WD repeat domain 73provided by HGNC Primary source HGNC:HGNC:25928 See related Ensembl:ENSG00000177082 MIM:616144; AllianceGenome:HGNC:25928 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAMOS; GAMOS1; HSPC264 Summary The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Expression Ubiquitous expression in thyroid (RPKM 6.8), prostate (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
WDR74, Official Symbol WDR74provided by HGNC Official Full Name WD repeat domain 74provided by HGNC Primary source HGNC:HGNC:25529 See related Ensembl:ENSG00000133316 MIM:617947; AllianceGenome:HGNC:25529 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Nsa1 Summary Involved in rRNA processing and ribosomal large subunit biogenesis. Located in nucleoplasm. Colocalizes with nuclear exosome (RNase complex) and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 9.1), ovary (RPKM 4.9) and 25 other tissues See more Orthologs mouse all
WDR75, Official Symbol WDR75provided by HGNC Official Full Name WD repeat domain 75provided by HGNC Primary source HGNC:HGNC:25725 See related Ensembl:ENSG00000115368 MIM:620341; AllianceGenome:HGNC:25725 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NET16; UTP17 Summary Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 14.9), endometrium (RPKM 14.7) and 25 other tissues See more Orthologs mouse all
WDR76, Official Symbol WDR76provided by HGNC Official Full Name WD repeat domain 76provided by HGNC Primary source HGNC:HGNC:25773 See related Ensembl:ENSG00000092470 MIM:620302; AllianceGenome:HGNC:25773 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMR1; CDW14 Summary Enables enzyme binding activity. Involved in cellular response to DNA damage stimulus. Located in heterochromatin; nucleus; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 6.6), bone marrow (RPKM 3.7) and 23 other tissues See more Orthologs mouse all
WDR77, Official Symbol WDR77provided by HGNC Official Full Name WD repeat domain 77provided by HGNC Primary source HGNC:HGNC:29652 See related Ensembl:ENSG00000116455 MIM:611734; AllianceGenome:HGNC:29652 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50 Summary The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in lymph node (RPKM 14.0), urinary bladder (RPKM 11.8) and 25 other tissues See more Orthologs mouse all
WDR81, Official Symbol WDR81provided by HGNC Official Full Name WD repeat domain 81provided by HGNC Primary source HGNC:HGNC:26600 See related Ensembl:ENSG00000167716 MIM:614218; AllianceGenome:HGNC:26600 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYC3; CHMRQ; CAMRQ2; SORF-2; PPP1R166 Summary This gene encodes a multi-domain transmembrane protein which is predominantly expressed in the brain and is thought to play a role in endolysosomal trafficking. Mutations in this gene are associated with an autosomal recessive form of a syndrome exhibiting cerebellar ataxia, cognitive disability, and disequilibrium (CAMRQ2). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in spleen (RPKM 7.6), lymph node (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
WDR82, Official Symbol WDR82provided by HGNC Official Full Name WD repeat domain 82provided by HGNC Primary source HGNC:HGNC:28826 See related Ensembl:ENSG00000164091 MIM:611059; AllianceGenome:HGNC:28826 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SWD2; MST107; WDR82A; MSTP107; PRO2730; TMEM113; PRO34047 Summary TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010] Expression Ubiquitous expression in brain (RPKM 35.2), endometrium (RPKM 34.7) and 25 other tissues See more Orthologs mouse all
WDR82P1, Official Symbol WDR82P1provided by HGNC Official Full Name WD repeat domain 82 pseudogene 1provided by HGNC Primary source HGNC:HGNC:32447 See related AllianceGenome:HGNC:32447 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SW2; SWD2; WDR82; WDR82B; hCG26824
WDR82P2, Official Symbol WDR82P2provided by HGNC Official Full Name WD repeat domain 82 pseudogene 2provided by HGNC Primary source HGNC:HGNC:33513 See related AllianceGenome:HGNC:33513 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WDR82C
WDR83, Official Symbol WDR83provided by HGNC Official Full Name WD repeat domain 83provided by HGNC Primary source HGNC:HGNC:32672 See related Ensembl:ENSG00000123154 MIM:616850; AllianceGenome:HGNC:32672 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MORG1 Summary This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in ovary (RPKM 12.2), skin (RPKM 10.9) and 25 other tissues See more Orthologs mouse all
WDR83OS, Official Symbol WDR83OSprovided by HGNC Official Full Name WD repeat domain 83 opposite strandprovided by HGNC Primary source HGNC:HGNC:30203 See related Ensembl:ENSG00000105583 MIM:618474; AllianceGenome:HGNC:30203 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAT10; PAT-10; PTD008; ASTERIX; C19orf56 Summary Enables protein folding chaperone. Involved in protein insertion into ER membrane. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 32.4), thyroid (RPKM 28.3) and 25 other tissues See more Orthologs mouse all
WDR86, Official Symbol WDR86provided by HGNC Official Full Name WD repeat domain 86provided by HGNC Primary source HGNC:HGNC:28020 See related Ensembl:ENSG00000187260 AllianceGenome:HGNC:28020 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in spleen (RPKM 5.6), endometrium (RPKM 5.4) and 25 other tissues See more Orthologs mouse all