psui3905/ncbi_genes_summary huggingface dataset:
YTHDF3, Official Symbol YTHDF3provided by HGNC Official Full Name YTH N6-methyladenosine RNA binding protein F3provided by HGNC Primary source HGNC:HGNC:26465 See related Ensembl:ENSG00000185728 MIM:618669; AllianceGenome:HGNC:26465 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DF3 Summary This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] Expression Ubiquitous expression in bone marrow (RPKM 27.1), colon (RPKM 15.4) and 25 other tissues See more Orthologs mouse all
YTHDF3-DT, Official Symbol YTHDF3-DTprovided by HGNC Official Full Name YTHDF3 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:48728 See related Ensembl:ENSG00000270673 AllianceGenome:HGNC:48728 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YTHDF3-AS1
YWHAB, Official Symbol YWHABprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein betaprovided by HGNC Primary source HGNC:HGNC:12849 See related Ensembl:ENSG00000166913 MIM:601289; AllianceGenome:HGNC:12849 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HS1; GW128; YWHAA; KCIP-1; HEL-S-1 Summary This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 158.2), lymph node (RPKM 85.8) and 24 other tissues See more Orthologs mouse all
YWHABP1, Official Symbol YWHABP1provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta pseudogene 1provided by HGNC Primary source HGNC:HGNC:50294 See related AllianceGenome:HGNC:50294 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAE, Official Symbol YWHAEprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilonprovided by HGNC Primary source HGNC:HGNC:12851 See related Ensembl:ENSG00000108953 MIM:605066; AllianceGenome:HGNC:12851 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDS; HEL2; MDCR; KCIP-1; 14-3-3E Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] Expression Ubiquitous expression in brain (RPKM 317.4), kidney (RPKM 169.5) and 25 other tissues See more Orthologs mouse all
YWHAEP3, Official Symbol YWHAEP3provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 3provided by HGNC Primary source HGNC:HGNC:49430 See related Ensembl:ENSG00000263976 AllianceGenome:HGNC:49430 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAEP4, Official Symbol YWHAEP4provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 4provided by HGNC Primary source HGNC:HGNC:49440 See related Ensembl:ENSG00000250205 AllianceGenome:HGNC:49440 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAEP7, Official Symbol YWHAEP7provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7provided by HGNC Primary source HGNC:HGNC:49437 See related Ensembl:ENSG00000290810 AllianceGenome:HGNC:49437 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
YWHAG, Official Symbol YWHAGprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gammaprovided by HGNC Primary source HGNC:HGNC:12852 See related Ensembl:ENSG00000170027 MIM:605356; AllianceGenome:HGNC:12852 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE56; EIEE56; PPP1R170; 14-3-3GAMMA Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 260.6), fat (RPKM 131.1) and 22 other tissues See more Orthologs mouse all
YWHAH, Official Symbol YWHAHprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein etaprovided by HGNC Primary source HGNC:HGNC:12853 See related Ensembl:ENSG00000128245 MIM:113508; AllianceGenome:HGNC:12853 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YWHA1 Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009] Expression Broad expression in brain (RPKM 343.5), lung (RPKM 62.6) and 22 other tissues See more Orthologs mouse all
YWHAQ, Official Symbol YWHAQprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein thetaprovided by HGNC Primary source HGNC:HGNC:12854 See related Ensembl:ENSG00000134308 MIM:609009; AllianceGenome:HGNC:12854 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 1C5; HS1; 14-3-3 Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 160.3), endometrium (RPKM 117.5) and 25 other tissues See more Orthologs mouse all
YWHAQP5, Official Symbol YWHAQP5provided by HGNC Official Full Name YWHAQ pseudogene 5provided by HGNC Primary source HGNC:HGNC:37684 See related Ensembl:ENSG00000236564 AllianceGenome:HGNC:37684 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAQP7, Official Symbol YWHAQP7provided by HGNC Official Full Name YWHAQ pseudogene 7provided by HGNC Primary source HGNC:HGNC:37686 See related Ensembl:ENSG00000271142 AllianceGenome:HGNC:37686 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAQP9, Official Symbol YWHAQP9provided by HGNC Official Full Name YWHAQ pseudogene 9provided by HGNC Primary source HGNC:HGNC:37688 See related AllianceGenome:HGNC:37688 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAZ, Official Symbol YWHAZprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zetaprovided by HGNC Primary source HGNC:HGNC:12855 See related Ensembl:ENSG00000164924 MIM:601288; AllianceGenome:HGNC:12855 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEL4; YWHAD; KCIP-1; HEL-S-3; POPCHAS; HEL-S-93; 14-3-3-zeta Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008] Expression Ubiquitous expression in esophagus (RPKM 248.0), brain (RPKM 160.0) and 25 other tissues See more Orthologs mouse all
YWHAZP1, Official Symbol YWHAZP1provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 1provided by HGNC Primary source HGNC:HGNC:19938 See related AllianceGenome:HGNC:19938 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YWHAZP
YWHAZP4, Official Symbol YWHAZP4provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 4provided by HGNC Primary source HGNC:HGNC:30851 See related AllianceGenome:HGNC:30851 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAZP5, Official Symbol YWHAZP5provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 5provided by HGNC Primary source HGNC:HGNC:30564 See related AllianceGenome:HGNC:30564 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YWHAZP6, Official Symbol YWHAZP6provided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 6provided by HGNC Primary source HGNC:HGNC:30849 See related AllianceGenome:HGNC:30849 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
YY1, Official Symbol YY1provided by HGNC Official Full Name YY1 transcription factorprovided by HGNC Primary source HGNC:HGNC:12856 See related Ensembl:ENSG00000100811 MIM:600013; AllianceGenome:HGNC:12856 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DELTA; NF-E1; UCRBP; GADEVS; INO80S; YIN-YANG-1 Summary YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 24.9), bone marrow (RPKM 20.9) and 25 other tissues See more Orthologs mouse all
YY1AP1, Official Symbol YY1AP1provided by HGNC Official Full Name YY1 associated protein 1provided by HGNC Primary source HGNC:HGNC:30935 See related Ensembl:ENSG00000163374 MIM:607860; AllianceGenome:HGNC:30935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GRNG; HCCA1; HCCA2; YY1AP Summary Predicted to enable transcription coregulator activity. Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in fibrillar center and nucleoplasm. Colocalizes with Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 35.6), bone marrow (RPKM 27.3) and 25 other tissues See more Orthologs all
YY2, Official Symbol YY2provided by HGNC Official Full Name YY2 transcription factorprovided by HGNC Primary source HGNC:HGNC:31684 See related Ensembl:ENSG00000230797 MIM:300570; AllianceGenome:HGNC:31684 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF631 Summary The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010] Orthologs mouse all
ZACN, Official Symbol ZACNprovided by HGNC Official Full Name zinc activated ion channelprovided by HGNC Primary source HGNC:HGNC:29504 See related Ensembl:ENSG00000186919 MIM:610935; AllianceGenome:HGNC:29504 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L2; ZAC; ZAC1; LGICZ; LGICZ1 Summary LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in prostate (RPKM 23.1), brain (RPKM 20.2) and 25 other tissues See more Orthologs all
ZACNP1, Official Symbol ZACNP1provided by HGNC Official Full Name zinc activated ion channel pseudogene 1provided by HGNC Primary source HGNC:HGNC:51915 See related AllianceGenome:HGNC:51915 Gene type pseudo RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZAN, Official Symbol ZANprovided by HGNC Official Full Name zonadhesinprovided by HGNC Primary source HGNC:HGNC:12857 See related Ensembl:ENSG00000146839 MIM:602372; AllianceGenome:HGNC:12857 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015] Annotation information Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Expression Low expression observed in reference dataset See more Orthologs mouse all
ZAP70, Official Symbol ZAP70provided by HGNC Official Full Name zeta chain of T cell receptor associated protein kinase 70provided by HGNC Primary source HGNC:HGNC:12858 See related Ensembl:ENSG00000115085 MIM:176947; AllianceGenome:HGNC:12858 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 Summary This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 11.2), spleen (RPKM 7.9) and 11 other tissues See more Orthologs mouse all
ZAR1, Official Symbol ZAR1provided by HGNC Official Full Name zygote arrest 1provided by HGNC Primary source HGNC:HGNC:20436 See related Ensembl:ENSG00000182223 MIM:607520; AllianceGenome:HGNC:20436 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Z3CXXC6 Summary This maternal effect gene is oocyte-specific and encodes a protein that is thought to function in the initiation of embryogenesis. A similar protein in mouse is required for female fertility. [provided by RefSeq, Jul 2013] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZAR1L, Official Symbol ZAR1Lprovided by HGNC Official Full Name zygote arrest 1 likeprovided by HGNC Primary source HGNC:HGNC:37116 See related Ensembl:ENSG00000189167 MIM:620424; AllianceGenome:HGNC:37116 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZAR2; Z3CXXC7 Summary This gene encodes a member of the ZAR1 family that is predominantly expressed in oocytes and early embryos. The protein may function as an RNA regulator in early embryos. [provided by RefSeq, Apr 2010] Expression Low expression observed in reference dataset See more Orthologs mouse all
ZBBX, Official Symbol ZBBXprovided by HGNC Official Full Name zinc finger B-box domain containingprovided by HGNC Primary source HGNC:HGNC:26245 See related Ensembl:ENSG00000169064 AllianceGenome:HGNC:26245 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable zinc ion binding activity. Predicted to be involved in cilium movement. Predicted to be active in motile cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 11.7) See more Orthologs mouse all
ZBED1, Official Symbol ZBED1provided by HGNC Official Full Name zinc finger BED-type containing 1provided by HGNC Primary source HGNC:HGNC:447 See related Ensembl:ENSG00000214717 Ensembl:ENSG00000292345 MIM:300178; AllianceGenome:HGNC:447 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALTE; DREF; TRAMP; hDREF Summary This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010] Expression Ubiquitous expression in kidney (RPKM 10.8), colon (RPKM 10.6) and 25 other tissues See more Orthologs all
ZBED2, Official Symbol ZBED2provided by HGNC Official Full Name zinc finger BED-type containing 2provided by HGNC Primary source HGNC:HGNC:20710 See related Ensembl:ENSG00000177494 MIM:615246; AllianceGenome:HGNC:20710 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables transcription cis-regulatory region binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of keratinocyte differentiation. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in thyroid (RPKM 46.0), lung (RPKM 7.6) and 2 other tissues See more Orthologs all
ZBED3, Official Symbol ZBED3provided by HGNC Official Full Name zinc finger BED-type containing 3provided by HGNC Primary source HGNC:HGNC:20711 See related Ensembl:ENSG00000132846 MIM:615250; AllianceGenome:HGNC:20711 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene belongs to a class of genes that arose through hAT DNA transposition and that encode regulatory proteins. This gene is upregulated in lung cancer tissues, where the encoded protein causes an accumulation of beta-catenin and enhanced lung cancer cell invasion. In addition, the encoded protein can be secreted and be involved in resistance to insulin. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in fat (RPKM 5.0), kidney (RPKM 4.8) and 25 other tissues See more Orthologs mouse all
ZBED3-AS1, Official Symbol ZBED3-AS1provided by HGNC Official Full Name ZBED3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44188 See related Ensembl:ENSG00000250802 AllianceGenome:HGNC:44188 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as lnc13728 Expression Broad expression in thyroid (RPKM 2.3), fat (RPKM 2.0) and 17 other tissues See more
ZBED4, Official Symbol ZBED4provided by HGNC Official Full Name zinc finger BED-type containing 4provided by HGNC Primary source HGNC:HGNC:20721 See related Ensembl:ENSG00000100426 MIM:612552; AllianceGenome:HGNC:20721 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables identical protein binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 4.8), colon (RPKM 4.3) and 25 other tissues See more Orthologs mouse all
ZBED5, Official Symbol ZBED5provided by HGNC Official Full Name zinc finger BED-type containing 5provided by HGNC Primary source HGNC:HGNC:30803 See related Ensembl:ENSG00000236287 MIM:615251; AllianceGenome:HGNC:30803 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Buster1 Summary This gene is unusual in that its coding sequence is mostly derived from Charlie-like DNA transposon; however, it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein is conserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009] Expression Ubiquitous expression in lymph node (RPKM 23.1), endometrium (RPKM 21.4) and 25 other tissues See more Orthologs all
ZBED5-AS1, Official Symbol ZBED5-AS1provided by HGNC Official Full Name ZBED5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48646 See related Ensembl:ENSG00000247271 AllianceGenome:HGNC:48646 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 17.3), thyroid (RPKM 9.7) and 25 other tissues See more
ZBED6, Official Symbol ZBED6provided by HGNC Official Full Name zinc finger BED-type containing 6provided by HGNC Primary source HGNC:HGNC:33273 See related Ensembl:ENSG00000257315 MIM:613512; AllianceGenome:HGNC:33273 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MGR Summary The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene. [provided by RefSeq, Jul 2016] Orthologs mouse all
ZBP1, Official Symbol ZBP1provided by HGNC Official Full Name Z-DNA binding protein 1provided by HGNC Primary source HGNC:HGNC:16176 See related Ensembl:ENSG00000124256 MIM:606750; AllianceGenome:HGNC:16176 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAI; DLM1; DLM-1; C20orf183 Summary This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Annotation information Note: ZBP1 (Gene ID: 81030) and IGF2BP1 (Gene ID:10642) share the ZBP1 symbol/alias in common. ZBP1 is a widely used alternative name for insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1), which can be confused with the official symbol for ZBP1, Z-DNA binding protein 1 (ZBP1). [09 Aug 2021] Expression Biased expression in spleen (RPKM 3.6), appendix (RPKM 3.2) and 13 other tissues See more Orthologs mouse all
ZBTB1, Official Symbol ZBTB1provided by HGNC Official Full Name zinc finger and BTB domain containing 1provided by HGNC Primary source HGNC:HGNC:20259 See related Ensembl:ENSG00000126804 MIM:616578; AllianceGenome:HGNC:20259 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF909 Summary Enables K63-linked polyubiquitin modification-dependent protein binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including cellular response to UV; nucleobase-containing compound biosynthetic process; and protein homooligomerization. Located in centrosome; nuclear body; and nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 14.1), lymph node (RPKM 11.3) and 25 other tissues See more Orthologs mouse all
ZBTB10, Official Symbol ZBTB10provided by HGNC Official Full Name zinc finger and BTB domain containing 10provided by HGNC Primary source HGNC:HGNC:30953 See related Ensembl:ENSG00000205189 MIM:618576; AllianceGenome:HGNC:30953 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RINZF Summary Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 6.2), placenta (RPKM 5.4) and 25 other tissues See more Orthologs mouse all
ZBTB11, Official Symbol ZBTB11provided by HGNC Official Full Name zinc finger and BTB domain containing 11provided by HGNC Primary source HGNC:HGNC:16740 See related Ensembl:ENSG00000066422 MIM:618181; AllianceGenome:HGNC:16740 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRT69; ZNF913; ZNF-U69274 Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 8.1), testis (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
ZBTB11-AS1, Official Symbol ZBTB11-AS1provided by HGNC Official Full Name ZBTB11 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48573 See related Ensembl:ENSG00000256628 AllianceGenome:HGNC:48573 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ZBTB12, Official Symbol ZBTB12provided by HGNC Official Full Name zinc finger and BTB domain containing 12provided by HGNC Primary source HGNC:HGNC:19066 See related Ensembl:ENSG00000204366 AllianceGenome:HGNC:19066 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G10; Bat9; NG35; D6S59E; C6orf46 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 4.1), endometrium (RPKM 1.9) and 23 other tissues See more Orthologs mouse all
ZBTB14, Official Symbol ZBTB14provided by HGNC Official Full Name zinc finger and BTB domain containing 14provided by HGNC Primary source HGNC:HGNC:12860 See related Ensembl:ENSG00000198081 MIM:602126; AllianceGenome:HGNC:12860 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZF5; ZFP-5; ZFP161; ZNF478; ZFP-161 Summary Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in negative regulation of transcription, DNA-templated. Located in aggresome; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 9.0), appendix (RPKM 6.6) and 25 other tissues See more Orthologs mouse all
ZBTB16, Official Symbol ZBTB16provided by HGNC Official Full Name zinc finger and BTB domain containing 16provided by HGNC Primary source HGNC:HGNC:12930 See related Ensembl:ENSG00000109906 MIM:176797; AllianceGenome:HGNC:12930 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLZF; ZNF145 Summary This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 27.9), ovary (RPKM 22.2) and 19 other tissues See more Orthologs mouse all
ZBTB17, Official Symbol ZBTB17provided by HGNC Official Full Name zinc finger and BTB domain containing 17provided by HGNC Primary source HGNC:HGNC:12936 See related Ensembl:ENSG00000116809 MIM:604084; AllianceGenome:HGNC:12936 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIZ-1; ZNF60; ZNF151; pHZ-67 Summary This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 10.4), testis (RPKM 10.3) and 25 other tissues See more Orthologs mouse all
ZBTB18, Official Symbol ZBTB18provided by HGNC Official Full Name zinc finger and BTB domain containing 18provided by HGNC Primary source HGNC:HGNC:13030 See related Ensembl:ENSG00000179456 MIM:608433; AllianceGenome:HGNC:13030 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP58; MRD22; TAZ-1; ZNF238; C2H2-171; DEL1Q42Q44; DEL1Q43Q44; C1DELq42q44; C1DELq43q44 Summary This gene encodes a C2H2-type zinc finger protein which acts a transcriptional repressor of genes involved in neuronal development. The encoded protein recognizes a specific sequence motif and recruits components of chromatin to target genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] Expression Ubiquitous expression in brain (RPKM 20.3), testis (RPKM 12.1) and 25 other tissues See more Orthologs mouse all
ZBTB2, Official Symbol ZBTB2provided by HGNC Official Full Name zinc finger and BTB domain containing 2provided by HGNC Primary source HGNC:HGNC:20868 See related Ensembl:ENSG00000181472 MIM:616595; AllianceGenome:HGNC:20868 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF437 Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 17.1), lymph node (RPKM 6.4) and 25 other tissues See more Orthologs mouse all
ZBTB20, Official Symbol ZBTB20provided by HGNC Official Full Name zinc finger and BTB domain containing 20provided by HGNC Primary source HGNC:HGNC:13503 See related Ensembl:ENSG00000181722 MIM:606025; AllianceGenome:HGNC:13503 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOF; DPZF; PRIMS; ODA-8S; ZNF288 Summary This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in kidney (RPKM 4.0), ovary (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
ZBTB20-AS1, Official Symbol ZBTB20-AS1provided by HGNC Official Full Name ZBTB20 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40640 See related Ensembl:ENSG00000241560 AllianceGenome:HGNC:40640 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 16.0) and ovary (RPKM 1.3) See more
ZBTB20-AS3, Official Symbol ZBTB20-AS3provided by HGNC Official Full Name ZBTB20 antisense RNA 3provided by HGNC Primary source HGNC:HGNC:42422 See related Ensembl:ENSG00000239946 AllianceGenome:HGNC:42422 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZBTB20-AS4, Official Symbol ZBTB20-AS4provided by HGNC Official Full Name ZBTB20 antisense RNA 4provided by HGNC Primary source HGNC:HGNC:42423 See related Ensembl:ENSG00000242767 AllianceGenome:HGNC:42423 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZBTB20-AS5, Official Symbol ZBTB20-AS5provided by HGNC Official Full Name ZBTB20 antisense RNA 5provided by HGNC Primary source HGNC:HGNC:52841 See related Ensembl:ENSG00000242290 AllianceGenome:HGNC:52841 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ZBTB21, Official Symbol ZBTB21provided by HGNC Official Full Name zinc finger and BTB domain containing 21provided by HGNC Primary source HGNC:HGNC:13083 See related Ensembl:ENSG00000173276 MIM:616485; AllianceGenome:HGNC:13083 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF295 Summary Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; POZ domain binding activity; and methyl-CpG binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 15.8), gall bladder (RPKM 5.4) and 23 other tissues See more Orthologs mouse all
ZBTB22, Official Symbol ZBTB22provided by HGNC Official Full Name zinc finger and BTB domain containing 22provided by HGNC Primary source HGNC:HGNC:13085 See related Ensembl:ENSG00000236104 MIM:611439; AllianceGenome:HGNC:13085 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as fru; BING1; ZNF297; ZBTB22A; ZNF297A; fruitless Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 7.3), thyroid (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
ZBTB24, Official Symbol ZBTB24provided by HGNC Official Full Name zinc finger and BTB domain containing 24provided by HGNC Primary source HGNC:HGNC:21143 See related Ensembl:ENSG00000112365 MIM:614064; AllianceGenome:HGNC:21143 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIF1; ICF2; PATZ2; ZNF450 Summary Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in nucleus. Implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 2. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 6.3), testis (RPKM 4.0) and 25 other tissues See more Orthologs mouse all
ZBTB25, Official Symbol ZBTB25provided by HGNC Official Full Name zinc finger and BTB domain containing 25provided by HGNC Primary source HGNC:HGNC:13112 See related Ensembl:ENSG00000089775 MIM:194541; AllianceGenome:HGNC:13112 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KUP; ZNF46; C14orf51 Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in liver (RPKM 4.4), thyroid (RPKM 2.4) and 25 other tissues See more Orthologs mouse all
ZBTB26, Official Symbol ZBTB26provided by HGNC Official Full Name zinc finger and BTB domain containing 26provided by HGNC Primary source HGNC:HGNC:23383 See related Ensembl:ENSG00000171448 MIM:620164; AllianceGenome:HGNC:23383 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF481; bioref Summary Enables identical protein binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 7.0), ovary (RPKM 4.9) and 25 other tissues See more Orthologs mouse all