psui3905/ncbi_genes_summary huggingface dataset:
USP2, Official Symbol USP2provided by HGNC Official Full Name ubiquitin specific peptidase 2provided by HGNC Primary source HGNC:HGNC:12618 See related Ensembl:ENSG00000036672 MIM:604725; AllianceGenome:HGNC:12618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP9; UBP41 Summary This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] Expression Biased expression in testis (RPKM 31.4), kidney (RPKM 15.4) and 10 other tissues See more Orthologs mouse all
USP20, Official Symbol USP20provided by HGNC Official Full Name ubiquitin specific peptidase 20provided by HGNC Primary source HGNC:HGNC:12619 See related Ensembl:ENSG00000136878 MIM:615143; AllianceGenome:HGNC:12619 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VDU2; hVDU2; LSFR3A Summary This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in lymph node (RPKM 8.9), bone marrow (RPKM 8.3) and 25 other tissues See more Orthologs mouse all
USP21, Official Symbol USP21provided by HGNC Official Full Name ubiquitin specific peptidase 21provided by HGNC Primary source HGNC:HGNC:12620 See related Ensembl:ENSG00000143258 MIM:604729; AllianceGenome:HGNC:12620 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP16; USP23 Summary This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in ovary (RPKM 11.4), testis (RPKM 9.2) and 25 other tissues See more Orthologs mouse all
USP21P2, Official Symbol USP21P2provided by HGNC Official Full Name USP21 pseudogene 2provided by HGNC Primary source HGNC:HGNC:54650 See related Ensembl:ENSG00000271356 AllianceGenome:HGNC:54650 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP22, Official Symbol USP22provided by HGNC Official Full Name ubiquitin specific peptidase 22provided by HGNC Primary source HGNC:HGNC:12621 See related Ensembl:ENSG00000124422 MIM:612116; AllianceGenome:HGNC:12621 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP3L Summary Enables enzyme binding activity; nuclear receptor coactivator activity; and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase activity. Involved in positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-templated; and protein modification by small protein conjugation or removal. Part of SAGA complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 54.0), ovary (RPKM 38.9) and 25 other tissues See more Orthologs mouse all
USP24, Official Symbol USP24provided by HGNC Official Full Name ubiquitin specific peptidase 24provided by HGNC Primary source HGNC:HGNC:12623 See related Ensembl:ENSG00000162402 MIM:610569; AllianceGenome:HGNC:12623 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in bone marrow (RPKM 9.9), lymph node (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
USP24P1, Official Symbol USP24P1provided by HGNC Official Full Name ubiquitin specific peptidase 24 pseudogene 1provided by HGNC Primary source HGNC:HGNC:42014 See related Ensembl:ENSG00000229375 AllianceGenome:HGNC:42014 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP25, Official Symbol USP25provided by HGNC Official Full Name ubiquitin specific peptidase 25provided by HGNC Primary source HGNC:HGNC:12624 See related Ensembl:ENSG00000155313 MIM:604736; AllianceGenome:HGNC:12624 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP21 Summary Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 20.1), endometrium (RPKM 11.0) and 25 other tissues See more Orthologs mouse all
USP26, Official Symbol USP26provided by HGNC Official Full Name ubiquitin specific peptidase 26provided by HGNC Primary source HGNC:HGNC:13485 See related Ensembl:ENSG00000134588 MIM:300309; AllianceGenome:HGNC:13485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPGFX6 Summary This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
USP27X, Official Symbol USP27Xprovided by HGNC Official Full Name ubiquitin specific peptidase 27 X-linkedprovided by HGNC Primary source HGNC:HGNC:13486 See related Ensembl:ENSG00000273820 MIM:300975; AllianceGenome:HGNC:13486 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP27; MRX105; USP22L; XLID105 Summary This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016] Orthologs mouse all
USP27X-DT, Official Symbol USP27X-DTprovided by HGNC Official Full Name USP27X divergent transcriptprovided by HGNC Primary source HGNC:HGNC:27249 See related Ensembl:ENSG00000234390 AllianceGenome:HGNC:27249 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP27X-AS1 Expression Ubiquitous expression in ovary (RPKM 1.6), thyroid (RPKM 1.4) and 23 other tissues See more
USP28, Official Symbol USP28provided by HGNC Official Full Name ubiquitin specific peptidase 28provided by HGNC Primary source HGNC:HGNC:12625 See related Ensembl:ENSG00000048028 MIM:610748; AllianceGenome:HGNC:12625 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in heart (RPKM 11.8), lymph node (RPKM 4.2) and 24 other tissues See more Orthologs mouse all
USP29, Official Symbol USP29provided by HGNC Official Full Name ubiquitin specific peptidase 29provided by HGNC Primary source HGNC:HGNC:18563 See related Ensembl:ENSG00000131864 MIM:609546; AllianceGenome:HGNC:18563 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOM-TES-84/86 Summary Predicted to enable cysteine-type endopeptidase activity and thiol-dependent deubiquitinase. Predicted to be involved in G1/S transition of mitotic cell cycle and protein deubiquitination. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 2.8) See more Orthologs mouse all
USP3, Official Symbol USP3provided by HGNC Official Full Name ubiquitin specific peptidase 3provided by HGNC Primary source HGNC:HGNC:12626 See related Ensembl:ENSG00000140455 MIM:604728; AllianceGenome:HGNC:12626 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBP; SIH003 Summary Enables histone binding activity and thiol-dependent deubiquitinase. Involved in several processes, including DNA repair; histone deubiquitination; and regulation of protein stability. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 9.8), spleen (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
USP3-AS1, Official Symbol USP3-AS1provided by HGNC Official Full Name USP3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44140 See related Ensembl:ENSG00000259248 AllianceGenome:HGNC:44140 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in bone marrow (RPKM 9.5), testis (RPKM 5.4) and 25 other tissues See more
USP30, Official Symbol USP30provided by HGNC Official Full Name ubiquitin specific peptidase 30provided by HGNC Primary source HGNC:HGNC:20065 See related Ensembl:ENSG00000135093 MIM:612492; AllianceGenome:HGNC:20065 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008] Expression Ubiquitous expression in testis (RPKM 5.7), ovary (RPKM 5.5) and 25 other tissues See more Orthologs mouse all
USP31, Official Symbol USP31provided by HGNC Official Full Name ubiquitin specific peptidase 31provided by HGNC Primary source HGNC:HGNC:20060 See related Ensembl:ENSG00000103404 MIM:619536; AllianceGenome:HGNC:20060 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables thiol-dependent deubiquitinase. Involved in protein deubiquitination. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 7.0), urinary bladder (RPKM 3.7) and 24 other tissues See more Orthologs mouse all
USP32, Official Symbol USP32provided by HGNC Official Full Name ubiquitin specific peptidase 32provided by HGNC Primary source HGNC:HGNC:19143 See related Ensembl:ENSG00000170832 MIM:607740; AllianceGenome:HGNC:19143 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP10; NY-REN-60 Summary Enables thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 36.8), brain (RPKM 14.5) and 23 other tissues See more Orthologs mouse all
USP32P1, Official Symbol USP32P1provided by HGNC Official Full Name ubiquitin specific peptidase 32 pseudogene 1provided by HGNC Primary source HGNC:HGNC:43570 See related Ensembl:ENSG00000290976 AllianceGenome:HGNC:43570 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 29.5), bone marrow (RPKM 9.3) and 21 other tissues See more
USP32P2, Official Symbol USP32P2provided by HGNC Official Full Name ubiquitin specific peptidase 32 pseudogene 2provided by HGNC Primary source HGNC:HGNC:30751 See related Ensembl:ENSG00000290659 AllianceGenome:HGNC:30751 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TL132 Expression Broad expression in testis (RPKM 12.1), bone marrow (RPKM 6.2) and 22 other tissues See more
USP33, Official Symbol USP33provided by HGNC Official Full Name ubiquitin specific peptidase 33provided by HGNC Primary source HGNC:HGNC:20059 See related Ensembl:ENSG00000077254 MIM:615146; AllianceGenome:HGNC:20059 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VDU1 Summary This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012] Expression Ubiquitous expression in fat (RPKM 19.0), brain (RPKM 15.9) and 25 other tissues See more Orthologs mouse all
USP34, Official Symbol USP34provided by HGNC Official Full Name ubiquitin specific peptidase 34provided by HGNC Primary source HGNC:HGNC:20066 See related Ensembl:ENSG00000115464 MIM:615295; AllianceGenome:HGNC:20066 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables cysteine-type endopeptidase activity and thiol-dependent deubiquitinase. Involved in positive regulation of canonical Wnt signaling pathway and protein K48-linked deubiquitination. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 17.6), lymph node (RPKM 17.0) and 25 other tissues See more Orthologs mouse all
USP35, Official Symbol USP35provided by HGNC Official Full Name ubiquitin specific peptidase 35provided by HGNC Primary source HGNC:HGNC:20061 See related Ensembl:ENSG00000118369 AllianceGenome:HGNC:20061 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in adrenal (RPKM 3.3), brain (RPKM 2.1) and 25 other tissues See more Orthologs mouse all
USP36, Official Symbol USP36provided by HGNC Official Full Name ubiquitin specific peptidase 36provided by HGNC Primary source HGNC:HGNC:20062 See related Ensembl:ENSG00000055483 MIM:612543; AllianceGenome:HGNC:20062 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUB1 Summary This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in bone marrow (RPKM 11.2), adrenal (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
USP37, Official Symbol USP37provided by HGNC Official Full Name ubiquitin specific peptidase 37provided by HGNC Primary source HGNC:HGNC:20063 See related Ensembl:ENSG00000135913 MIM:620226; AllianceGenome:HGNC:20063 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables cysteine-type endopeptidase activity; protein kinase binding activity; and thiol-dependent deubiquitinase. Involved in G1/S transition of mitotic cell cycle; protein deubiquitination; and regulation of DNA replication. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 8.0), small intestine (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
USP37P1, Official Symbol USP37P1provided by HGNC Official Full Name USP37 pseudogene 1provided by HGNC Primary source HGNC:HGNC:55020 See related AllianceGenome:HGNC:55020 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP38, Official Symbol USP38provided by HGNC Official Full Name ubiquitin specific peptidase 38provided by HGNC Primary source HGNC:HGNC:20067 See related Ensembl:ENSG00000170185 MIM:618322; AllianceGenome:HGNC:20067 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HP43.8KD Summary Enables thiol-dependent deubiquitinase. Involved in protein deubiquitination. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 7.3), colon (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
USP39, Official Symbol USP39provided by HGNC Official Full Name ubiquitin specific peptidase 39provided by HGNC Primary source HGNC:HGNC:20071 See related Ensembl:ENSG00000168883 MIM:611594; AllianceGenome:HGNC:20071 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 65K; SAD1; CGI-21; HSPC332; SNRNP65 Summary Predicted to enable thiol-dependent deubiquitinase and zinc ion binding activity. Involved in spliceosomal complex assembly. Located in nucleoplasm. Part of U4/U6 x U5 tri-snRNP complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 14.6), placenta (RPKM 13.8) and 25 other tissues See more Orthologs mouse all
USP4, Official Symbol USP4provided by HGNC Official Full Name ubiquitin specific peptidase 4provided by HGNC Primary source HGNC:HGNC:12627 See related Ensembl:ENSG00000114316 MIM:603486; AllianceGenome:HGNC:12627 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNP; Unph Summary The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in testis (RPKM 15.1), bone marrow (RPKM 14.6) and 25 other tissues See more Orthologs mouse all
USP40, Official Symbol USP40provided by HGNC Official Full Name ubiquitin specific peptidase 40provided by HGNC Primary source HGNC:HGNC:20069 See related Ensembl:ENSG00000085982 MIM:610570; AllianceGenome:HGNC:20069 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 7.5), thyroid (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
USP42, Official Symbol USP42provided by HGNC Official Full Name ubiquitin specific peptidase 42provided by HGNC Primary source HGNC:HGNC:20068 See related Ensembl:ENSG00000106346 AllianceGenome:HGNC:20068 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables thiol-dependent deubiquitinase. Involved in protein deubiquitination. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 9.2), bone marrow (RPKM 4.1) and 24 other tissues See more Orthologs mouse all
USP43, Official Symbol USP43provided by HGNC Official Full Name ubiquitin specific peptidase 43provided by HGNC Primary source HGNC:HGNC:20072 See related Ensembl:ENSG00000154914 AllianceGenome:HGNC:20072 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ISG15-specific protease activity. Predicted to be involved in translesion synthesis. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in placenta (RPKM 3.1), prostate (RPKM 3.0) and 19 other tissues See more Orthologs mouse all
USP44, Official Symbol USP44provided by HGNC Official Full Name ubiquitin specific peptidase 44provided by HGNC Primary source HGNC:HGNC:20064 See related Ensembl:ENSG00000136014 MIM:610993; AllianceGenome:HGNC:20064 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a protease that functions as a deubiquitinating enzyme. The encoded protein is thought to help regulate the spindle assembly checkpoint by preventing early anaphase onset. This protein specifically deubiquitinates CDC20, which stabilizes the anaphase promoting complex/cyclosome. [provided by RefSeq, Dec 2016] Expression Biased expression in testis (RPKM 9.0), lung (RPKM 1.3) and 1 other tissue See more Orthologs mouse all
USP45, Official Symbol USP45provided by HGNC Official Full Name ubiquitin specific peptidase 45provided by HGNC Primary source HGNC:HGNC:20080 See related Ensembl:ENSG00000123552 MIM:618439; AllianceGenome:HGNC:20080 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCA19 Summary The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in gall bladder (RPKM 1.4), small intestine (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
USP46, Official Symbol USP46provided by HGNC Official Full Name ubiquitin specific peptidase 46provided by HGNC Primary source HGNC:HGNC:20075 See related Ensembl:ENSG00000109189 MIM:612849; AllianceGenome:HGNC:20075 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009] Expression Ubiquitous expression in brain (RPKM 11.8), heart (RPKM 7.4) and 23 other tissues See more Orthologs mouse all
USP46-DT, Official Symbol USP46-DTprovided by HGNC Official Full Name USP46 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:43991 See related Ensembl:ENSG00000248866 AllianceGenome:HGNC:43991 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP46-AS1 Expression Ubiquitous expression in heart (RPKM 4.4), kidney (RPKM 4.3) and 24 other tissues See more
USP47, Official Symbol USP47provided by HGNC Official Full Name ubiquitin specific peptidase 47provided by HGNC Primary source HGNC:HGNC:20076 See related Ensembl:ENSG00000170242 MIM:614460; AllianceGenome:HGNC:20076 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRFP Summary Enables WD40-repeat domain binding activity and thiol-dependent deubiquitinase. Involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of G2/M transition of mitotic cell cycle; and negative regulation of nitrogen compound metabolic process. Located in cytoplasm. Part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 11.7), heart (RPKM 10.2) and 25 other tissues See more Orthologs mouse all
USP48, Official Symbol USP48provided by HGNC Official Full Name ubiquitin specific peptidase 48provided by HGNC Primary source HGNC:HGNC:18533 See related Ensembl:ENSG00000090686 MIM:617445; AllianceGenome:HGNC:18533 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP31; DFNA85; RAP1GA1 Summary This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 9.7), lymph node (RPKM 7.9) and 25 other tissues See more Orthologs mouse all
USP49, Official Symbol USP49provided by HGNC Official Full Name ubiquitin specific peptidase 49provided by HGNC Primary source HGNC:HGNC:20078 See related Ensembl:ENSG00000164663 AllianceGenome:HGNC:20078 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables cysteine-type endopeptidase activity; histone binding activity; and thiol-dependent deubiquitinase. Involved in histone H2B conserved C-terminal lysine deubiquitination and mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 2.1), thyroid (RPKM 1.8) and 25 other tissues See more Orthologs mouse all
USP5, Official Symbol USP5provided by HGNC Official Full Name ubiquitin specific peptidase 5provided by HGNC Primary source HGNC:HGNC:12628 See related Ensembl:ENSG00000111667 MIM:601447; AllianceGenome:HGNC:12628 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISOT Summary Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010] Expression Ubiquitous expression in testis (RPKM 36.2), brain (RPKM 33.4) and 25 other tissues See more Orthologs mouse all
USP50, Official Symbol USP50provided by HGNC Official Full Name ubiquitin specific peptidase 50provided by HGNC Primary source HGNC:HGNC:20079 See related Ensembl:ENSG00000170236 AllianceGenome:HGNC:20079 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin-like protein-specific protease activity. Acts upstream of or within several processes, including nuclear speck organization; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of macromolecule metabolic process. Predicted to be active in several cellular components, including dendritic spine; midbody; and postsynaptic density. Predicted to be extrinsic component of endosome membrane and extrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 3.5), bone marrow (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
USP51, Official Symbol USP51provided by HGNC Official Full Name ubiquitin specific peptidase 51provided by HGNC Primary source HGNC:HGNC:23086 See related Ensembl:ENSG00000247746 AllianceGenome:HGNC:23086 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables chromatin binding activity; histone binding activity; and thiol-dependent deubiquitinase. Involved in histone deubiquitination; regulation of cell cycle process; and regulation of double-strand break repair. Predicted to be located in chromosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 4.9), ovary (RPKM 3.8) and 23 other tissues See more Orthologs mouse all
USP53, Official Symbol USP53provided by HGNC Official Full Name ubiquitin specific peptidase 53provided by HGNC Primary source HGNC:HGNC:29255 See related Ensembl:ENSG00000145390 MIM:617431; AllianceGenome:HGNC:29255 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFIC7 Summary Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential and neuron apoptotic process. Predicted to be located in bicellular tight junction. Predicted to be active in cell-cell junction. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 25.2), colon (RPKM 12.3) and 24 other tissues See more Orthologs mouse all
USP54, Official Symbol USP54provided by HGNC Official Full Name ubiquitin specific peptidase 54provided by HGNC Primary source HGNC:HGNC:23513 See related Ensembl:ENSG00000166348 AllianceGenome:HGNC:23513 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C10orf29; bA137L10.3; bA137L10.4 Summary Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 13.4), brain (RPKM 8.5) and 22 other tissues See more Orthologs mouse all
USP6, Official Symbol USP6provided by HGNC Official Full Name ubiquitin specific peptidase 6provided by HGNC Primary source HGNC:HGNC:12629 See related Ensembl:ENSG00000129204 MIM:604334; AllianceGenome:HGNC:12629 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HRP1; TRE2; TRE17; Tre-2; TRESMCR; USP6-short Summary Enables thiol-dependent deubiquitinase. Involved in protein deubiquitination and regulation of vesicle-mediated transport. Located in plasma membrane and recycling endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 9.4), ovary (RPKM 2.5) and 9 other tissues See more Orthologs all
USP6NL, Official Symbol USP6NLprovided by HGNC Official Full Name USP6 N-terminal likeprovided by HGNC Primary source HGNC:HGNC:16858 See related Ensembl:ENSG00000148429 MIM:605405; AllianceGenome:HGNC:16858 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNTRE; TRE2NL; USP6NL-IT1 Summary Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including plasma membrane to endosome transport; positive regulation of GTPase activity; and retrograde transport, plasma membrane to Golgi. Located in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 11.0), esophagus (RPKM 10.8) and 24 other tissues See more Orthologs mouse all
USP6NL-AS1, Official Symbol USP6NL-AS1provided by HGNC Official Full Name USP6NL antisense RNA 1provided by HGNC Primary source HGNC:HGNC:55251 See related Ensembl:ENSG00000271360 AllianceGenome:HGNC:55251 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Orthologs all
USP7, Official Symbol USP7provided by HGNC Official Full Name ubiquitin specific peptidase 7provided by HGNC Primary source HGNC:HGNC:12630 See related Ensembl:ENSG00000187555 MIM:602519; AllianceGenome:HGNC:12630 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TEF1; HAUSP; HAFOUS; DEL16P13.2; C16DELp13.2 Summary The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in testis (RPKM 31.0), lymph node (RPKM 24.1) and 25 other tissues See more Orthologs mouse all
USP7-AS1, Official Symbol USP7-AS1provided by HGNC Official Full Name USP7 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:55379 See related Ensembl:ENSG00000260979 AllianceGenome:HGNC:55379 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
USP8, Official Symbol USP8provided by HGNC Official Full Name ubiquitin specific peptidase 8provided by HGNC Primary source HGNC:HGNC:12631 See related Ensembl:ENSG00000138592 MIM:603158; AllianceGenome:HGNC:12631 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBPY; PITA4; SPG59; HumORF8 Summary This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in testis (RPKM 16.5), thyroid (RPKM 12.8) and 25 other tissues See more Orthologs mouse all
USP9X, Official Symbol USP9Xprovided by HGNC Official Full Name ubiquitin specific peptidase 9 X-linkedprovided by HGNC Primary source HGNC:HGNC:12632 See related Ensembl:ENSG00000124486 MIM:300072; AllianceGenome:HGNC:12632 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAF; FAM; hFAM; DFFRX; MRX99; XLID99; MRXS99F Summary This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 14.2), thyroid (RPKM 14.0) and 25 other tissues See more Orthologs mouse all
USP9Y, Official Symbol USP9Yprovided by HGNC Official Full Name ubiquitin specific peptidase 9 Y-linkedprovided by HGNC Primary source HGNC:HGNC:12633 See related Ensembl:ENSG00000114374 MIM:400005; AllianceGenome:HGNC:12633 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFFRY; SPGFY2 Summary This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009] Expression Broad expression in prostate (RPKM 5.7), testis (RPKM 2.9) and 20 other tissues See more Orthologs all
USP9YP1, Official Symbol USP9YP1provided by HGNC Official Full Name USP9Y pseudogene 1provided by HGNC Primary source HGNC:HGNC:31741 See related AllianceGenome:HGNC:31741 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP10, Official Symbol USP9YP10provided by HGNC Official Full Name USP9Y pseudogene 10provided by HGNC Primary source HGNC:HGNC:38454 See related Ensembl:ENSG00000238135 AllianceGenome:HGNC:38454 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP13, Official Symbol USP9YP13provided by HGNC Official Full Name USP9Y pseudogene 13provided by HGNC Primary source HGNC:HGNC:38721 See related AllianceGenome:HGNC:38721 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP14, Official Symbol USP9YP14provided by HGNC Official Full Name USP9Y pseudogene 14provided by HGNC Primary source HGNC:HGNC:38748 See related Ensembl:ENSG00000227494 AllianceGenome:HGNC:38748 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP15, Official Symbol USP9YP15provided by HGNC Official Full Name USP9Y pseudogene 15provided by HGNC Primary source HGNC:HGNC:38751 See related Ensembl:ENSG00000233120 AllianceGenome:HGNC:38751 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP16, Official Symbol USP9YP16provided by HGNC Official Full Name USP9Y pseudogene 16provided by HGNC Primary source HGNC:HGNC:38752 See related Ensembl:ENSG00000232744 AllianceGenome:HGNC:38752 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP17, Official Symbol USP9YP17provided by HGNC Official Full Name USP9Y pseudogene 17provided by HGNC Primary source HGNC:HGNC:38753 See related Ensembl:ENSG00000229553 AllianceGenome:HGNC:38753 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
USP9YP18, Official Symbol USP9YP18provided by HGNC Official Full Name USP9Y pseudogene 18provided by HGNC Primary source HGNC:HGNC:38754 See related Ensembl:ENSG00000223407 AllianceGenome:HGNC:38754 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo