psui3905/ncbi_genes_summary huggingface dataset:
TUBA4A, Official Symbol TUBA4Aprovided by HGNC Official Full Name tubulin alpha 4aprovided by HGNC Primary source HGNC:HGNC:12407 See related Ensembl:ENSG00000127824 MIM:191110; AllianceGenome:HGNC:12407 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALS22; TUBA1; H2-ALPHA Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] Expression Broad expression in skin (RPKM 72.2), brain (RPKM 48.6) and 20 other tissues See more Orthologs all
TUBA4B, Official Symbol TUBA4Bprovided by HGNC Official Full Name tubulin alpha 4bprovided by HGNC Primary source HGNC:HGNC:18637 See related Ensembl:ENSG00000243910 AllianceGenome:HGNC:18637 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBA4 Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in skin (RPKM 5.0), brain (RPKM 4.3) and 21 other tissues See more Orthologs all
TUBA8, Official Symbol TUBA8provided by HGNC Official Full Name tubulin alpha 8provided by HGNC Primary source HGNC:HGNC:12410 See related Ensembl:ENSG00000183785 MIM:605742; AllianceGenome:HGNC:12410 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDCBM8; TUBAL2; MACTHC2 Summary This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] Expression Biased expression in heart (RPKM 36.8), testis (RPKM 14.8) and 3 other tissues See more Orthologs mouse all
TUBAL3, Official Symbol TUBAL3provided by HGNC Official Full Name tubulin alpha like 3provided by HGNC Primary source HGNC:HGNC:23534 See related Ensembl:ENSG00000178462 AllianceGenome:HGNC:23534 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in small intestine (RPKM 13.2), duodenum (RPKM 10.7) and 2 other tissues See more Orthologs mouse all
TUBAP1, Official Symbol TUBAP1provided by HGNC Official Full Name tubulin alpha pseudogene 1provided by HGNC Primary source HGNC:HGNC:12411 See related Ensembl:ENSG00000237569 AllianceGenome:HGNC:12411 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBAP
TUBAP10, Official Symbol TUBAP10provided by HGNC Official Full Name tubulin alpha pseudogene 10provided by HGNC Primary source HGNC:HGNC:54877 See related Ensembl:ENSG00000248506 AllianceGenome:HGNC:54877 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP11, Official Symbol TUBAP11provided by HGNC Official Full Name tubulin alpha pseudogene 11provided by HGNC Primary source HGNC:HGNC:54878 See related Ensembl:ENSG00000259751 AllianceGenome:HGNC:54878 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP12, Official Symbol TUBAP12provided by HGNC Official Full Name tubulin alpha pseudogene 12provided by HGNC Primary source HGNC:HGNC:54879 See related Ensembl:ENSG00000259614 AllianceGenome:HGNC:54879 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP13, Official Symbol TUBAP13provided by HGNC Official Full Name tubulin alpha pseudogene 13provided by HGNC Primary source HGNC:HGNC:54880 See related Ensembl:ENSG00000242575 AllianceGenome:HGNC:54880 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP14, Official Symbol TUBAP14provided by HGNC Official Full Name tubulin alpha pseudogene 14provided by HGNC Primary source HGNC:HGNC:54881 See related Ensembl:ENSG00000247763 AllianceGenome:HGNC:54881 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP15, Official Symbol TUBAP15provided by HGNC Official Full Name tubulin alpha pseudogene 15provided by HGNC Primary source HGNC:HGNC:54882 See related Ensembl:ENSG00000250895 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP6, Official Symbol TUBAP6provided by HGNC Official Full Name tubulin alpha pseudogene 6provided by HGNC Primary source HGNC:HGNC:54873 See related Ensembl:ENSG00000274374 AllianceGenome:HGNC:54873 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP7, Official Symbol TUBAP7provided by HGNC Official Full Name tubulin alpha pseudogene 7provided by HGNC Primary source HGNC:HGNC:54874 See related Ensembl:ENSG00000253547 AllianceGenome:HGNC:54874 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP8, Official Symbol TUBAP8provided by HGNC Official Full Name tubulin alpha pseudogene 8provided by HGNC Primary source HGNC:HGNC:54875 See related Ensembl:ENSG00000238145 AllianceGenome:HGNC:54875 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBAP9, Official Symbol TUBAP9provided by HGNC Official Full Name tubulin alpha pseudogene 9provided by HGNC Primary source HGNC:HGNC:54876 See related Ensembl:ENSG00000225154 AllianceGenome:HGNC:54876 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB, Official Symbol TUBBprovided by HGNC Official Full Name tubulin beta class Iprovided by HGNC Primary source HGNC:HGNC:20778 See related Ensembl:ENSG00000196230 MIM:191130; AllianceGenome:HGNC:20778 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M40; TUBB1; TUBB5; CDCBM6; CSCSC1; OK/SW-cl.56 Summary This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014] Annotation information Note: TUBB1 (Gene ID: 81027) and TUBB (Gene ID: 203068) share the TUBB1 symbol/alias in common. TUBB (GeneID: 203068) also shares the TUBB symbol/alias in common with TUBB2A (Gene ID: 7280). [07 Feb 2019] Expression Ubiquitous expression in ovary (RPKM 250.9), bone marrow (RPKM 212.6) and 25 other tissues See more Orthologs mouse all
TUBB1, Official Symbol TUBB1provided by HGNC Official Full Name tubulin beta 1 class VIprovided by HGNC Primary source HGNC:HGNC:16257 See related Ensembl:ENSG00000101162 MIM:612901; AllianceGenome:HGNC:16257 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MACTHC1 Summary This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010] Annotation information Note: TUBB1 (Gene ID: 81027) and TUBB (Gene ID: 203068) share the TUBB1 symbol/alias in common. [07 Feb 2019] Expression Biased expression in bone marrow (RPKM 4.6), spleen (RPKM 3.2) and 10 other tissues See more Orthologs mouse all
TUBB1P2, Official Symbol TUBB1P2provided by HGNC Official Full Name tubulin beta 1 class VI pseudogene 2provided by HGNC Primary source HGNC:HGNC:23981 See related AllianceGenome:HGNC:23981 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB2A, Official Symbol TUBB2Aprovided by HGNC Official Full Name tubulin beta 2A class IIaprovided by HGNC Primary source HGNC:HGNC:12412 See related Ensembl:ENSG00000137267 MIM:615101; AllianceGenome:HGNC:12412 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBB; TUBB2; CDCBM5 Summary Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015] Annotation information Note: TUBB (GeneID: 203068) and TUBB2A (Gene ID: 7280) share the TUBB symbol/alias in common. [07 Feb 2019] Expression Broad expression in brain (RPKM 301.1), bone marrow (RPKM 37.9) and 16 other tissues See more Orthologs mouse all
TUBB2B, Official Symbol TUBB2Bprovided by HGNC Official Full Name tubulin beta 2B class IIbprovided by HGNC Primary source HGNC:HGNC:30829 See related Ensembl:ENSG00000137285 MIM:612850; AllianceGenome:HGNC:30829 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDCBM7; PMGYSA; bA506K6.1 Summary The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010] Expression Biased expression in brain (RPKM 233.4), bone marrow (RPKM 22.7) and 11 other tissues See more Orthologs all
TUBB2BP1, Official Symbol TUBB2BP1provided by HGNC Official Full Name tubulin beta 2B class IIb pseudogene 1provided by HGNC Primary source HGNC:HGNC:42332 See related Ensembl:ENSG00000216819 AllianceGenome:HGNC:42332 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB3, Official Symbol TUBB3provided by HGNC Official Full Name tubulin beta 3 class IIIprovided by HGNC Primary source HGNC:HGNC:20772 See related Ensembl:ENSG00000258947 MIM:602661; AllianceGenome:HGNC:20772 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A Summary This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010] Expression Broad expression in brain (RPKM 82.3), testis (RPKM 29.3) and 18 other tissues See more Orthologs mouse all
TUBB3P1, Official Symbol TUBB3P1provided by HGNC Official Full Name tubulin beta 3 class III pseudogene 1provided by HGNC Primary source HGNC:HGNC:42339 See related Ensembl:ENSG00000220418 AllianceGenome:HGNC:42339 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4A, Official Symbol TUBB4Aprovided by HGNC Official Full Name tubulin beta 4A class IVaprovided by HGNC Primary source HGNC:HGNC:20774 See related Ensembl:ENSG00000104833 MIM:602662; AllianceGenome:HGNC:20774 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DYT4; TUBB4; beta-5 Summary This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014] Expression Biased expression in brain (RPKM 224.5), adrenal (RPKM 54.5) and 1 other tissue See more Orthologs mouse all
TUBB4B, Official Symbol TUBB4Bprovided by HGNC Official Full Name tubulin beta 4B class IVbprovided by HGNC Primary source HGNC:HGNC:20771 See related Ensembl:ENSG00000188229 MIM:602660; AllianceGenome:HGNC:20771 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Beta2; TUBB2; LCAEOD; TUBB2C Summary Enables double-stranded RNA binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in microtubule. Implicated in Leber congenital amaurosis with early-onset deafness. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 398.3), bone marrow (RPKM 175.3) and 25 other tissues See more Orthologs mouse all
TUBB4BP1, Official Symbol TUBB4BP1provided by HGNC Official Full Name TUBB4B pseudogene 1provided by HGNC Primary source HGNC:HGNC:42180 See related Ensembl:ENSG00000255988 AllianceGenome:HGNC:42180 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4BP2, Official Symbol TUBB4BP2provided by HGNC Official Full Name TUBB4B pseudogene 2provided by HGNC Primary source HGNC:HGNC:42183 See related Ensembl:ENSG00000224802 AllianceGenome:HGNC:42183 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4BP4, Official Symbol TUBB4BP4provided by HGNC Official Full Name TUBB4B pseudogene 4provided by HGNC Primary source HGNC:HGNC:42333 See related Ensembl:ENSG00000254961 AllianceGenome:HGNC:42333 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4BP5, Official Symbol TUBB4BP5provided by HGNC Official Full Name TUBB4B pseudogene 5provided by HGNC Primary source HGNC:HGNC:42335 See related Ensembl:ENSG00000224062 AllianceGenome:HGNC:42335 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4BP6, Official Symbol TUBB4BP6provided by HGNC Official Full Name TUBB4B pseudogene 6provided by HGNC Primary source HGNC:HGNC:42336 Gene type pseudo Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
TUBB4BP7, Official Symbol TUBB4BP7provided by HGNC Official Full Name TUBB4B pseudogene 7provided by HGNC Primary source HGNC:HGNC:42337 See related AllianceGenome:HGNC:42337 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB4BP8, Official Symbol TUBB4BP8provided by HGNC Official Full Name TUBB4B pseudogene 8provided by HGNC Primary source HGNC:HGNC:55021 See related Ensembl:ENSG00000227521 AllianceGenome:HGNC:55021 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB6, Official Symbol TUBB6provided by HGNC Official Full Name tubulin beta 6 class Vprovided by HGNC Primary source HGNC:HGNC:20776 See related Ensembl:ENSG00000176014 MIM:615103; AllianceGenome:HGNC:20776 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FPVEPD; TUBB-5; HsT1601 Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 41.4), esophagus (RPKM 38.3) and 25 other tissues See more Orthologs mouse all
TUBB8, Official Symbol TUBB8provided by HGNC Official Full Name tubulin beta 8 class VIIIprovided by HGNC Primary source HGNC:HGNC:20773 See related Ensembl:ENSG00000261456 MIM:616768; AllianceGenome:HGNC:20773 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OOMD; OOMD2; OZEMA2; bA631M21.2 Summary The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility. [provided by RefSeq, Mar 2016] Expression Low expression observed in reference dataset See more Orthologs all
TUBB8B, Official Symbol TUBB8Bprovided by HGNC Official Full Name tubulin beta 8Bprovided by HGNC Primary source HGNC:HGNC:24983 See related Ensembl:ENSG00000173213 AllianceGenome:HGNC:24983 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBB8P12 Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
TUBB8P1, Official Symbol TUBB8P1provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 1provided by HGNC Primary source HGNC:HGNC:42182 See related Ensembl:ENSG00000229298 AllianceGenome:HGNC:42182 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P10, Official Symbol TUBB8P10provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 10provided by HGNC Primary source HGNC:HGNC:42348 See related Ensembl:ENSG00000237469 AllianceGenome:HGNC:42348 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P11, Official Symbol TUBB8P11provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 11provided by HGNC Primary source HGNC:HGNC:32337 See related Ensembl:ENSG00000234711 AllianceGenome:HGNC:32337 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P2, Official Symbol TUBB8P2provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 2provided by HGNC Primary source HGNC:HGNC:42334 See related Ensembl:ENSG00000218896 AllianceGenome:HGNC:42334 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P3, Official Symbol TUBB8P3provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 3provided by HGNC Primary source HGNC:HGNC:42338 See related Ensembl:ENSG00000250307 AllianceGenome:HGNC:42338 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P4, Official Symbol TUBB8P4provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 4provided by HGNC Primary source HGNC:HGNC:42185 See related Ensembl:ENSG00000250788 AllianceGenome:HGNC:42185 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P5, Official Symbol TUBB8P5provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 5provided by HGNC Primary source HGNC:HGNC:42186 See related Ensembl:ENSG00000254381 AllianceGenome:HGNC:42186 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P6, Official Symbol TUBB8P6provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 6provided by HGNC Primary source HGNC:HGNC:42343 See related Ensembl:ENSG00000224625 AllianceGenome:HGNC:42343 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P7, Official Symbol TUBB8P7provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 7provided by HGNC Primary source HGNC:HGNC:42345 See related Ensembl:ENSG00000261812 AllianceGenome:HGNC:42345 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P8, Official Symbol TUBB8P8provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 8provided by HGNC Primary source HGNC:HGNC:42346 See related Ensembl:ENSG00000213113 AllianceGenome:HGNC:42346 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBB8P9, Official Symbol TUBB8P9provided by HGNC Official Full Name tubulin beta 8 class VIII pseudogene 9provided by HGNC Primary source HGNC:HGNC:42347 See related Ensembl:ENSG00000235827 AllianceGenome:HGNC:42347 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBBP1, Official Symbol TUBBP1provided by HGNC Official Full Name tubulin beta pseudogene 1provided by HGNC Primary source HGNC:HGNC:12414 See related Ensembl:ENSG00000127589 AllianceGenome:HGNC:12414 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBBP11, Official Symbol TUBBP11provided by HGNC Official Full Name tubulin beta class I pseudogene 11provided by HGNC Primary source HGNC:HGNC:42184 See related Ensembl:ENSG00000243195 AllianceGenome:HGNC:42184 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBBP3, Official Symbol TUBBP3provided by HGNC Official Full Name tubulin beta pseudogene 3provided by HGNC Primary source HGNC:HGNC:18192 See related AllianceGenome:HGNC:18192 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBBP6, Official Symbol TUBBP6provided by HGNC Official Full Name tubulin beta class I pseudogene 6provided by HGNC Primary source HGNC:HGNC:42175 See related Ensembl:ENSG00000235207 AllianceGenome:HGNC:42175 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBBP9, Official Symbol TUBBP9provided by HGNC Official Full Name tubulin beta class I pseudogene 9provided by HGNC Primary source HGNC:HGNC:42178 See related Ensembl:ENSG00000220586 AllianceGenome:HGNC:42178 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBD1, Official Symbol TUBD1provided by HGNC Official Full Name tubulin delta 1provided by HGNC Primary source HGNC:HGNC:16811 See related Ensembl:ENSG00000108423 MIM:607344; AllianceGenome:HGNC:16811 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBD Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and positive regulation of smoothened signaling pathway. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 3.8), thyroid (RPKM 3.7) and 25 other tissues See more Orthologs mouse all
TUBE1, Official Symbol TUBE1provided by HGNC Official Full Name tubulin epsilon 1provided by HGNC Primary source HGNC:HGNC:20775 See related Ensembl:ENSG00000074935 MIM:607345; AllianceGenome:HGNC:20775 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBE; dJ142L7.2 Summary This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009] Expression Broad expression in testis (RPKM 21.9), endometrium (RPKM 10.2) and 25 other tissues See more Orthologs mouse all
TUBG1, Official Symbol TUBG1provided by HGNC Official Full Name tubulin gamma 1provided by HGNC Primary source HGNC:HGNC:12417 See related Ensembl:ENSG00000131462 MIM:191135; AllianceGenome:HGNC:12417 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBG; GCP-1; CDCBM4; TUBGCP1 Summary This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009] Expression Broad expression in testis (RPKM 90.1), bone marrow (RPKM 18.5) and 23 other tissues See more Orthologs mouse all
TUBG1P, Official Symbol TUBG1Pprovided by HGNC Official Full Name tubulin gamma 1 pseudogeneprovided by HGNC Primary source HGNC:HGNC:12418 See related Ensembl:ENSG00000237972 AllianceGenome:HGNC:12418 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TUBG2, Official Symbol TUBG2provided by HGNC Official Full Name tubulin gamma 2provided by HGNC Primary source HGNC:HGNC:12419 See related Ensembl:ENSG00000037042 MIM:605785; AllianceGenome:HGNC:12419 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic sister chromatid segregation. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 19.4), testis (RPKM 16.1) and 25 other tissues See more Orthologs all
TUBGCP2, Official Symbol TUBGCP2provided by HGNC Official Full Name tubulin gamma complex component 2provided by HGNC Primary source HGNC:HGNC:18599 See related Ensembl:ENSG00000130640 MIM:617817; AllianceGenome:HGNC:18599 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALP4; GCP2; GCP-2; SPC97; h103p; hGCP2; SPBC97; Spc97p; hSpc97; Grip103; PAMDDFS Summary Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Involved in brain development and neuron migration. Located in centrosome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 14.0), kidney (RPKM 12.2) and 25 other tissues See more Orthologs mouse all
TUBGCP3, Official Symbol TUBGCP3provided by HGNC Official Full Name tubulin gamma complex component 3provided by HGNC Primary source HGNC:HGNC:18598 See related Ensembl:ENSG00000126216 MIM:617818; AllianceGenome:HGNC:18598 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 104p; ALP6; GCP3; Spc98; SPBC98; Spc98p; Grip104 Summary Enables gamma-tubulin binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Located in cytoplasm and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.5), ovary (RPKM 6.0) and 25 other tissues See more Orthologs mouse all
TUBGCP4, Official Symbol TUBGCP4provided by HGNC Official Full Name tubulin gamma complex component 4provided by HGNC Primary source HGNC:HGNC:16691 See related Ensembl:ENSG00000137822 MIM:609610; AllianceGenome:HGNC:16691 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 76P; GCP4; GCP-4; Grip76; MCCRP3 Summary This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] Expression Ubiquitous expression in brain (RPKM 7.5), thyroid (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
TUBGCP5, Official Symbol TUBGCP5provided by HGNC Official Full Name tubulin gamma complex component 5provided by HGNC Primary source HGNC:HGNC:18600 See related Ensembl:ENSG00000275835 MIM:608147; AllianceGenome:HGNC:18600 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCP5 Summary Enables microtubule binding activity. Involved in microtubule nucleation. Located in centrosome and cytosol. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.8), brain (RPKM 3.5) and 25 other tissues See more Orthologs mouse all
TUBGCP6, Official Symbol TUBGCP6provided by HGNC Official Full Name tubulin gamma complex component 6provided by HGNC Primary source HGNC:HGNC:18127 See related Ensembl:ENSG00000128159 MIM:610053; AllianceGenome:HGNC:18127 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCP6; GCP-6; MCCRP; MCCRP1; MCPHCR Summary The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in spleen (RPKM 17.1), lymph node (RPKM 14.4) and 25 other tissues See more Orthologs mouse all
TUFM, Official Symbol TUFMprovided by HGNC Official Full Name Tu translation elongation factor, mitochondrialprovided by HGNC Primary source HGNC:HGNC:12420 See related Ensembl:ENSG00000178952 MIM:602389; AllianceGenome:HGNC:12420 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P43; EFTU; COXPD4; EF-TuMT Summary This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 62.5), colon (RPKM 52.5) and 25 other tissues See more Orthologs mouse all
TUFMP1, Official Symbol TUFMP1provided by HGNC Official Full Name Tu translation elongation factor, mitochondrial pseudogene 1provided by HGNC Primary source HGNC:HGNC:12421 See related Ensembl:ENSG00000265646 AllianceGenome:HGNC:12421 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUFML
TUFT1, Official Symbol TUFT1provided by HGNC Official Full Name tuftelin 1provided by HGNC Primary source HGNC:HGNC:12422 See related Ensembl:ENSG00000143367 MIM:600087; AllianceGenome:HGNC:12422 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WHSF Summary Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014] Expression Broad expression in skin (RPKM 29.7), esophagus (RPKM 10.9) and 19 other tissues See more Orthologs mouse all
TUG1, Official Symbol TUG1provided by HGNC Official Full Name taurine up-regulated 1provided by HGNC Primary source HGNC:HGNC:26066 See related Ensembl:ENSG00000253352 MIM:614971; AllianceGenome:HGNC:26066 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TI-227H; LINC00080; NCRNA00080 Summary Predicted to act upstream of or within photoreceptor cell development and regulation of gene expression. Predicted to be active in nucleus. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 36.1), endometrium (RPKM 31.7) and 25 other tissues See more Orthologs mouse all
TULP1, Official Symbol TULP1provided by HGNC Official Full Name TUB like protein 1provided by HGNC Primary source HGNC:HGNC:12423 See related Ensembl:ENSG00000112041 MIM:602280; AllianceGenome:HGNC:12423 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP14; LCA15; TUBL1 Summary This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. The protein encoded by this gene is thought to play a role in the physiology of photoreceptors. Mutations in this gene are associated with recessive juvenile retinitis pigmentosa and Leber congenital amaurosis-15. [provided by RefSeq, Nov 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all
TULP2, Official Symbol TULP2provided by HGNC Official Full Name TUB like protein 2provided by HGNC Primary source HGNC:HGNC:12424 See related Ensembl:ENSG00000104804 MIM:602309; AllianceGenome:HGNC:12424 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT65; TUBL2 Summary TULP2 is a member of a family of tubby-like genes (TULPs) that encode proteins of unknown function. Members of this family have been identified in plants, vertebrates, and invertebrates. The TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 9.9) See more Orthologs mouse all
TULP3, Official Symbol TULP3provided by HGNC Official Full Name TUB like protein 3provided by HGNC Primary source HGNC:HGNC:12425 See related Ensembl:ENSG00000078246 MIM:604730; AllianceGenome:HGNC:12425 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HRCDF; TUBL3 Summary This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009] Expression Ubiquitous expression in ovary (RPKM 20.1), endometrium (RPKM 13.4) and 23 other tissues See more Orthologs mouse all
TULP4, Official Symbol TULP4provided by HGNC Official Full Name TUB like protein 4provided by HGNC Primary source HGNC:HGNC:15530 See related Ensembl:ENSG00000130338 MIM:619442; AllianceGenome:HGNC:15530 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUSP Summary Predicted to be involved in protein ubiquitination. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 5.2), testis (RPKM 3.3) and 25 other tissues See more Orthologs mouse all
TUSC1, Official Symbol TUSC1provided by HGNC Official Full Name tumor suppressor candidate 1provided by HGNC Primary source HGNC:HGNC:31010 See related Ensembl:ENSG00000198680 MIM:610529; AllianceGenome:HGNC:31010 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSG9; TSG-9; CCDC89B Summary This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008] Orthologs mouse all
TUSC2, Official Symbol TUSC2provided by HGNC Official Full Name tumor suppressor 2, mitochondrial calcium regulatorprovided by HGNC Primary source HGNC:HGNC:17034 See related Ensembl:ENSG00000114383 MIM:607052; AllianceGenome:HGNC:17034 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP; FUS1; PDAP2; C3orf11 Summary Predicted to be involved in inflammatory response and regulation of mitochondrial membrane potential. Predicted to act upstream of or within several processes, including natural killer cell differentiation; neutrophil-mediated killing of gram-negative bacterium; and regulation of cytokine production. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 15.7), kidney (RPKM 12.1) and 25 other tissues See more Orthologs mouse all
TUSC2P1, Official Symbol TUSC2P1provided by HGNC Official Full Name TUSC2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:23963 See related Ensembl:ENSG00000285470 AllianceGenome:HGNC:23963 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUSC2P