psui3905/ncbi_genes_summary huggingface dataset:
HMGB1P19, Official Symbol HMGB1P19provided by HGNC Official Full Name high mobility group box 1 pseudogene 19provided by HGNC Primary source HGNC:HGNC:39101 See related Ensembl:ENSG00000253463 AllianceGenome:HGNC:39101 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P21, Official Symbol HMGB1P21provided by HGNC Official Full Name high mobility group box 1 pseudogene 21provided by HGNC Primary source HGNC:HGNC:39106 See related AllianceGenome:HGNC:39106 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P22, Official Symbol HMGB1P22provided by HGNC Official Full Name high mobility group box 1 pseudogene 22provided by HGNC Primary source HGNC:HGNC:39107 See related AllianceGenome:HGNC:39107 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P23, Official Symbol HMGB1P23provided by HGNC Official Full Name high mobility group box 1 pseudogene 23provided by HGNC Primary source HGNC:HGNC:39114 See related Ensembl:ENSG00000253770 AllianceGenome:HGNC:39114 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P30, Official Symbol HMGB1P30provided by HGNC Official Full Name high mobility group box 1 pseudogene 30provided by HGNC Primary source HGNC:HGNC:39121 See related Ensembl:ENSG00000244089 AllianceGenome:HGNC:39121 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P31, Official Symbol HMGB1P31provided by HGNC Official Full Name high mobility group box 1 pseudogene 31provided by HGNC Primary source HGNC:HGNC:39122 See related Ensembl:ENSG00000233266 AllianceGenome:HGNC:39122 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P32, Official Symbol HMGB1P32provided by HGNC Official Full Name high mobility group box 1 pseudogene 32provided by HGNC Primary source HGNC:HGNC:39123 See related Ensembl:ENSG00000226837 AllianceGenome:HGNC:39123 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P33, Official Symbol HMGB1P33provided by HGNC Official Full Name high mobility group box 1 pseudogene 33provided by HGNC Primary source HGNC:HGNC:39124 See related Ensembl:ENSG00000261174 AllianceGenome:HGNC:39124 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P35, Official Symbol HMGB1P35provided by HGNC Official Full Name high mobility group box 1 pseudogene 35provided by HGNC Primary source HGNC:HGNC:39175 See related Ensembl:ENSG00000251566 AllianceGenome:HGNC:39175 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P36, Official Symbol HMGB1P36provided by HGNC Official Full Name high mobility group box 1 pseudogene 36provided by HGNC Primary source HGNC:HGNC:39176 See related Ensembl:ENSG00000243873 AllianceGenome:HGNC:39176 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P38, Official Symbol HMGB1P38provided by HGNC Official Full Name high mobility group box 1 pseudogene 38provided by HGNC Primary source HGNC:HGNC:39185 See related AllianceGenome:HGNC:39185 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P39, Official Symbol HMGB1P39provided by HGNC Official Full Name high mobility group box 1 pseudogene 39provided by HGNC Primary source HGNC:HGNC:39186 See related Ensembl:ENSG00000203489 AllianceGenome:HGNC:39186 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P4, Official Symbol HMGB1P4provided by HGNC Official Full Name high mobility group box 1 pseudogene 4provided by HGNC Primary source HGNC:HGNC:4996 See related AllianceGenome:HGNC:4996 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG1L4; HMG1L4P; HMGB1L4
HMGB1P40, Official Symbol HMGB1P40provided by HGNC Official Full Name high mobility group box 1 pseudogene 40provided by HGNC Primary source HGNC:HGNC:39187 See related AllianceGenome:HGNC:39187 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P41, Official Symbol HMGB1P41provided by HGNC Official Full Name high mobility group box 1 pseudogene 41provided by HGNC Primary source HGNC:HGNC:39188 See related AllianceGenome:HGNC:39188 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P44, Official Symbol HMGB1P44provided by HGNC Official Full Name high mobility group box 1 pseudogene 44provided by HGNC Primary source HGNC:HGNC:39275 See related Ensembl:ENSG00000248956 AllianceGenome:HGNC:39275 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P45, Official Symbol HMGB1P45provided by HGNC Official Full Name high mobility group box 1 pseudogene 45provided by HGNC Primary source HGNC:HGNC:39277 See related AllianceGenome:HGNC:39277 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P46, Official Symbol HMGB1P46provided by HGNC Official Full Name high mobility group box 1 pseudogene 46provided by HGNC Primary source HGNC:HGNC:39279 See related Ensembl:ENSG00000254146 AllianceGenome:HGNC:39279 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P47, Official Symbol HMGB1P47provided by HGNC Official Full Name high mobility group box 1 pseudogene 47provided by HGNC Primary source HGNC:HGNC:39280 See related AllianceGenome:HGNC:39280 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P48, Official Symbol HMGB1P48provided by HGNC Official Full Name high mobility group box 1 pseudogene 48provided by HGNC Primary source HGNC:HGNC:39281 See related AllianceGenome:HGNC:39281 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P49, Official Symbol HMGB1P49provided by HGNC Official Full Name high mobility group box 1 pseudogene 49provided by HGNC Primary source HGNC:HGNC:39282 See related Ensembl:ENSG00000230519 AllianceGenome:HGNC:39282 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P5, Official Symbol HMGB1P5provided by HGNC Official Full Name high mobility group box 1 pseudogene 5provided by HGNC Primary source HGNC:HGNC:4997 See related Ensembl:ENSG00000132967 AllianceGenome:HGNC:4997 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG-1; HMG1L5; HMGB1L5; HMGB1P2; HMGB1L15
HMGB1P50, Official Symbol HMGB1P50provided by HGNC Official Full Name high mobility group box 1 pseudogene 50provided by HGNC Primary source HGNC:HGNC:52368 See related Ensembl:ENSG00000271237 AllianceGenome:HGNC:52368 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB1P7, Official Symbol HMGB1P7provided by HGNC Official Full Name high mobility group box 1 pseudogene 7provided by HGNC Primary source HGNC:HGNC:39096 See related Ensembl:ENSG00000231148 AllianceGenome:HGNC:39096 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB2, Official Symbol HMGB2provided by HGNC Official Full Name high mobility group box 2provided by HGNC Primary source HGNC:HGNC:5000 See related Ensembl:ENSG00000164104 MIM:163906; AllianceGenome:HGNC:5000 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG2 Summary This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 603.0), lymph node (RPKM 141.8) and 10 other tissues See more Orthologs mouse all
HMGB2P1, Official Symbol HMGB2P1provided by HGNC Official Full Name high mobility group box 2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:39174 See related AllianceGenome:HGNC:39174 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3, Official Symbol HMGB3provided by HGNC Official Full Name high mobility group box 3provided by HGNC Primary source HGNC:HGNC:5004 See related Ensembl:ENSG00000029993 MIM:300193; AllianceGenome:HGNC:5004 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG4; HMG-4; HMG2A; HMG-2a Summary This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Broad expression in placenta (RPKM 24.9), bone marrow (RPKM 7.8) and 21 other tissues See more Orthologs mouse all
HMGB3P10, Official Symbol HMGB3P10provided by HGNC Official Full Name high mobility group box 3 pseudogene 10provided by HGNC Primary source HGNC:HGNC:39302 See related Ensembl:ENSG00000223656 AllianceGenome:HGNC:39302 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P14, Official Symbol HMGB3P14provided by HGNC Official Full Name high mobility group box 3 pseudogene 14provided by HGNC Primary source HGNC:HGNC:39306 See related Ensembl:ENSG00000231845 AllianceGenome:HGNC:39306 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P15, Official Symbol HMGB3P15provided by HGNC Official Full Name high mobility group box 3 pseudogene 15provided by HGNC Primary source HGNC:HGNC:39307 See related Ensembl:ENSG00000250897 AllianceGenome:HGNC:39307 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P16, Official Symbol HMGB3P16provided by HGNC Official Full Name high mobility group box 3 pseudogene 16provided by HGNC Primary source HGNC:HGNC:39308 See related Ensembl:ENSG00000248430 AllianceGenome:HGNC:39308 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P18, Official Symbol HMGB3P18provided by HGNC Official Full Name high mobility group box 3 pseudogene 18provided by HGNC Primary source HGNC:HGNC:39310 See related Ensembl:ENSG00000220184 AllianceGenome:HGNC:39310 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P21, Official Symbol HMGB3P21provided by HGNC Official Full Name high mobility group box 3 pseudogene 21provided by HGNC Primary source HGNC:HGNC:39313 See related Ensembl:ENSG00000224551 AllianceGenome:HGNC:39313 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P26, Official Symbol HMGB3P26provided by HGNC Official Full Name high mobility group box 3 pseudogene 26provided by HGNC Primary source HGNC:HGNC:39318 See related Ensembl:ENSG00000259428 AllianceGenome:HGNC:39318 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P27, Official Symbol HMGB3P27provided by HGNC Official Full Name high mobility group box 3 pseudogene 27provided by HGNC Primary source HGNC:HGNC:39319 See related Ensembl:ENSG00000267132 AllianceGenome:HGNC:39319 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P3, Official Symbol HMGB3P3provided by HGNC Official Full Name high mobility group box 3 pseudogene 3provided by HGNC Primary source HGNC:HGNC:39102 See related Ensembl:ENSG00000250730 AllianceGenome:HGNC:39102 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P30, Official Symbol HMGB3P30provided by HGNC Official Full Name high mobility group box 3 pseudogene 30provided by HGNC Primary source HGNC:HGNC:39333 See related Ensembl:ENSG00000213652 AllianceGenome:HGNC:39333 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P31, Official Symbol HMGB3P31provided by HGNC Official Full Name high mobility group box 3 pseudogene 31provided by HGNC Primary source HGNC:HGNC:39334 See related Ensembl:ENSG00000231929 AllianceGenome:HGNC:39334 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P4, Official Symbol HMGB3P4provided by HGNC Official Full Name high mobility group box 3 pseudogene 4provided by HGNC Primary source HGNC:HGNC:39104 See related Ensembl:ENSG00000228808 AllianceGenome:HGNC:39104 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P5, Official Symbol HMGB3P5provided by HGNC Official Full Name high mobility group box 3 pseudogene 5provided by HGNC Primary source HGNC:HGNC:39105 See related AllianceGenome:HGNC:39105 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P6, Official Symbol HMGB3P6provided by HGNC Official Full Name high mobility group box 3 pseudogene 6provided by HGNC Primary source HGNC:HGNC:39283 See related Ensembl:ENSG00000213070 AllianceGenome:HGNC:39283 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB3P9, Official Symbol HMGB3P9provided by HGNC Official Full Name high mobility group box 3 pseudogene 9provided by HGNC Primary source HGNC:HGNC:39301 See related AllianceGenome:HGNC:39301 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGB4, Official Symbol HMGB4provided by HGNC Official Full Name high mobility group box 4provided by HGNC Primary source HGNC:HGNC:24954 See related Ensembl:ENSG00000176256 MIM:617285; AllianceGenome:HGNC:24954 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ1007G16.5 Summary Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 70.9) See more Orthologs mouse all
HMGCL, Official Symbol HMGCLprovided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA lyaseprovided by HGNC Primary source HGNC:HGNC:5005 See related Ensembl:ENSG00000117305 MIM:613898; AllianceGenome:HGNC:5005 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HL; HMGCL1 Summary The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in liver (RPKM 67.1), kidney (RPKM 50.9) and 24 other tissues See more Orthologs mouse all
HMGCLL1, Official Symbol HMGCLL1provided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA lyase like 1provided by HGNC Primary source HGNC:HGNC:21359 See related Ensembl:ENSG00000146151 MIM:619050; AllianceGenome:HGNC:21359 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERCHL; er-cHL; bA418P12.1 Summary Enables hydroxymethylglutaryl-CoA lyase activity. Involved in ketone body biosynthetic process. Located in several cellular components, including cytosol; endoplasmic reticulum; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 2.9), adrenal (RPKM 1.2) and 14 other tissues See more Orthologs mouse all
HMGCR, Official Symbol HMGCRprovided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA reductaseprovided by HGNC Primary source HGNC:HGNC:5006 See related Ensembl:ENSG00000113161 MIM:142910; AllianceGenome:HGNC:5006 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYPLG; LDLCQ3; LGMDR28 Summary HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Expression Ubiquitous expression in brain (RPKM 31.2), colon (RPKM 23.2) and 25 other tissues See more Orthologs mouse all
HMGCS1, Official Symbol HMGCS1provided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA synthase 1provided by HGNC Primary source HGNC:HGNC:5007 See related Ensembl:ENSG00000112972 MIM:142940; AllianceGenome:HGNC:5007 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMGCS Summary Enables protein homodimerization activity. Predicted to be involved in acetyl-CoA metabolic process and farnesyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytoplasm. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 48.5), liver (RPKM 37.3) and 23 other tissues See more Orthologs mouse all
HMGCS2, Official Symbol HMGCS2provided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA synthase 2provided by HGNC Primary source HGNC:HGNC:5008 See related Ensembl:ENSG00000134240 MIM:600234; AllianceGenome:HGNC:5008 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] Expression Biased expression in liver (RPKM 471.6), colon (RPKM 127.8) and 5 other tissues See more Orthologs mouse all
HMGN1, Official Symbol HMGN1provided by HGNC Official Full Name high mobility group nucleosome binding domain 1provided by HGNC Primary source HGNC:HGNC:4984 See related Ensembl:ENSG00000205581 MIM:163920; AllianceGenome:HGNC:4984 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG14 Summary The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in bone marrow (RPKM 44.3), lymph node (RPKM 41.2) and 25 other tissues See more Orthologs mouse all
HMGN1P10, Official Symbol HMGN1P10provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 10provided by HGNC Primary source HGNC:HGNC:39353 See related Ensembl:ENSG00000244101 AllianceGenome:HGNC:39353 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P12, Official Symbol HMGN1P12provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 12provided by HGNC Primary source HGNC:HGNC:39356 See related Ensembl:ENSG00000247911 AllianceGenome:HGNC:39356 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P13, Official Symbol HMGN1P13provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 13provided by HGNC Primary source HGNC:HGNC:39357 See related Ensembl:ENSG00000249619 AllianceGenome:HGNC:39357 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P14, Official Symbol HMGN1P14provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 14provided by HGNC Primary source HGNC:HGNC:39358 See related Ensembl:ENSG00000249439 AllianceGenome:HGNC:39358 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P15, Official Symbol HMGN1P15provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 15provided by HGNC Primary source HGNC:HGNC:39359 See related Ensembl:ENSG00000250197 AllianceGenome:HGNC:39359 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P16, Official Symbol HMGN1P16provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 16provided by HGNC Primary source HGNC:HGNC:39360 See related Ensembl:ENSG00000249503 AllianceGenome:HGNC:39360 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P17, Official Symbol HMGN1P17provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 17provided by HGNC Primary source HGNC:HGNC:39361 See related Ensembl:ENSG00000250787 AllianceGenome:HGNC:39361 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P19, Official Symbol HMGN1P19provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 19provided by HGNC Primary source HGNC:HGNC:39363 See related Ensembl:ENSG00000224519 AllianceGenome:HGNC:39363 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P31, Official Symbol HMGN1P31provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 31provided by HGNC Primary source HGNC:HGNC:39375 See related Ensembl:ENSG00000267513 AllianceGenome:HGNC:39375 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P32, Official Symbol HMGN1P32provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 32provided by HGNC Primary source HGNC:HGNC:39376 See related Ensembl:ENSG00000237589 AllianceGenome:HGNC:39376 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P33, Official Symbol HMGN1P33provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 33provided by HGNC Primary source HGNC:HGNC:39377 See related Ensembl:ENSG00000230326 AllianceGenome:HGNC:39377 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P5, Official Symbol HMGN1P5provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 5provided by HGNC Primary source HGNC:HGNC:39348 See related Ensembl:ENSG00000230942 AllianceGenome:HGNC:39348 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P6, Official Symbol HMGN1P6provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 6provided by HGNC Primary source HGNC:HGNC:39349 See related Ensembl:ENSG00000224070 AllianceGenome:HGNC:39349 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P8, Official Symbol HMGN1P8provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogene 8provided by HGNC Primary source HGNC:HGNC:39351 See related Ensembl:ENSG00000241120 AllianceGenome:HGNC:39351 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN1P9, Official Symbol HMGN1P9provided by HGNC Official Full Name high mobility group nucleosome binding domain 1 pseudogeneprovided by HGNC Primary source HGNC:HGNC:39352 See related Ensembl:ENSG00000248377 AllianceGenome:HGNC:39352 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2, Official Symbol HMGN2provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2provided by HGNC Primary source HGNC:HGNC:4986 See related Ensembl:ENSG00000198830 MIM:163910; AllianceGenome:HGNC:4986 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMG17 Summary The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014] Expression Ubiquitous expression in bone marrow (RPKM 279.3), lymph node (RPKM 141.8) and 25 other tissues See more Orthologs mouse all
HMGN2P2, Official Symbol HMGN2P2provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 2provided by HGNC Primary source HGNC:HGNC:20016 See related AllianceGenome:HGNC:20016 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMGN2L2
HMGN2P20, Official Symbol HMGN2P20provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 20provided by HGNC Primary source HGNC:HGNC:39385 See related AllianceGenome:HGNC:39385 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P22, Official Symbol HMGN2P22provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 22provided by HGNC Primary source HGNC:HGNC:39387 See related AllianceGenome:HGNC:39387 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P24, Official Symbol HMGN2P24provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 24provided by HGNC Primary source HGNC:HGNC:39389 See related AllianceGenome:HGNC:39389 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P26, Official Symbol HMGN2P26provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 26provided by HGNC Primary source HGNC:HGNC:39393 See related Ensembl:ENSG00000241203 AllianceGenome:HGNC:39393 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P3, Official Symbol HMGN2P3provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 3provided by HGNC Primary source HGNC:HGNC:33566 See related AllianceGenome:HGNC:33566 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMGN2L3
HMGN2P32, Official Symbol HMGN2P32provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 32provided by HGNC Primary source HGNC:HGNC:39403 See related AllianceGenome:HGNC:39403 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P38, Official Symbol HMGN2P38provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 38provided by HGNC Primary source HGNC:HGNC:39409 See related AllianceGenome:HGNC:39409 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN2P47, Official Symbol HMGN2P47provided by HGNC Official Full Name high mobility group nucleosomal binding domain 2 pseudogene 47provided by HGNC Primary source HGNC:HGNC:44422 See related AllianceGenome:HGNC:44422 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HMGN3, Official Symbol HMGN3provided by HGNC Official Full Name high mobility group nucleosomal binding domain 3provided by HGNC Primary source HGNC:HGNC:12312 See related Ensembl:ENSG00000118418 MIM:604502; AllianceGenome:HGNC:12312 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIP7; PNAS-24; PNAS-25 Summary The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in heart (RPKM 45.8), adrenal (RPKM 40.5) and 25 other tissues See more Orthologs mouse all
HMGN3-AS1, Official Symbol HMGN3-AS1provided by HGNC Official Full Name HMGN3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48984 See related Ensembl:ENSG00000270362 AllianceGenome:HGNC:48984 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in fat (RPKM 2.9), kidney (RPKM 2.8) and 25 other tissues See more
HMGN4, Official Symbol HMGN4provided by HGNC Official Full Name high mobility group nucleosomal binding domain 4provided by HGNC Primary source HGNC:HGNC:4989 See related Ensembl:ENSG00000182952 AllianceGenome:HGNC:4989 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NHC; HMG17L3 Summary The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. [provided by RefSeq, Mar 2013] Expression Ubiquitous expression in lymph node (RPKM 30.6), thyroid (RPKM 30.3) and 25 other tissues See more Orthologs all
HMGN5, Official Symbol HMGN5provided by HGNC Official Full Name high mobility group nucleosome binding domain 5provided by HGNC Primary source HGNC:HGNC:8013 See related Ensembl:ENSG00000198157 MIM:300385; AllianceGenome:HGNC:8013 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NSBP1; NBP-45 Summary This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009] Expression Broad expression in testis (RPKM 20.5), adrenal (RPKM 4.3) and 20 other tissues See more Orthologs mouse all
HMGXB3, Official Symbol HMGXB3provided by HGNC Official Full Name HMG-box containing 3provided by HGNC Primary source HGNC:HGNC:28982 See related Ensembl:ENSG00000113716 MIM:619800; AllianceGenome:HGNC:28982 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMF; HMGX3 Summary This gene is one of the non-canonical high mobility group (HMG) genes. The encoded protein contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in prostate (RPKM 10.5), testis (RPKM 9.2) and 25 other tissues See more Orthologs mouse all
HMGXB4, Official Symbol HMGXB4provided by HGNC Official Full Name HMG-box containing 4provided by HGNC Primary source HGNC:HGNC:5003 See related Ensembl:ENSG00000100281 MIM:604702; AllianceGenome:HGNC:5003 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P53N; HMG2L1; HMGBCG; THC211630 Summary High mobility group (HMG) proteins are nonhistone chromosomal proteins. See HMG2 (MIM 163906) for additional information on HMG proteins.[supplied by OMIM, Nov 2010] Expression Ubiquitous expression in testis (RPKM 8.3), bone marrow (RPKM 7.9) and 25 other tissues See more Orthologs mouse all
HMHB1, Official Symbol HMHB1provided by HGNC Official Full Name histocompatibility minor HB-1provided by HGNC Primary source HGNC:HGNC:29677 See related Ensembl:ENSG00000158497 MIM:609961; AllianceGenome:HGNC:29677 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HB-1; HB-1Y; HLA-HB1 Summary This gene encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). This gene is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs all
HMMR, Official Symbol HMMRprovided by HGNC Official Full Name hyaluronan mediated motility receptorprovided by HGNC Primary source HGNC:HGNC:5012 See related Ensembl:ENSG00000072571 MIM:600936; AllianceGenome:HGNC:5012 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD168; IHABP; RHAMM Summary The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008] Expression Biased expression in testis (RPKM 12.7), lymph node (RPKM 9.0) and 11 other tissues See more Orthologs mouse all
HMOX1, Official Symbol HMOX1provided by HGNC Official Full Name heme oxygenase 1provided by HGNC Primary source HGNC:HGNC:5013 See related Ensembl:ENSG00000100292 MIM:141250; AllianceGenome:HGNC:5013 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HO-1; HSP32; HMOX1D; bK286B10 Summary Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] Expression Broad expression in spleen (RPKM 208.2), ovary (RPKM 68.8) and 17 other tissues See more Orthologs mouse all
HMOX2, Official Symbol HMOX2provided by HGNC Official Full Name heme oxygenase 2provided by HGNC Primary source HGNC:HGNC:5014 See related Ensembl:ENSG00000103415 MIM:141251; AllianceGenome:HGNC:5014 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HO-2 Summary Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] Expression Ubiquitous expression in testis (RPKM 23.0), brain (RPKM 16.1) and 25 other tissues See more Orthologs mouse all