psui3905/ncbi_genes_summary huggingface dataset:
DTX3L, Official Symbol DTX3Lprovided by HGNC Official Full Name deltex E3 ubiquitin ligase 3Lprovided by HGNC Primary source HGNC:HGNC:30323 See related Ensembl:ENSG00000163840 MIM:613143; AllianceGenome:HGNC:30323 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BBAP; RNF143 Summary Enables several functions, including STAT family protein binding activity; ubiquitin-like protein ligase binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of protein localization; and protein ubiquitination. Located in cytosol; lysosome; and nucleoplasm. Part of protein-containing complex. Colocalizes with early endosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 14.2), spleen (RPKM 13.2) and 25 other tissues See more Orthologs mouse all
DTX4, Official Symbol DTX4provided by HGNC Official Full Name deltex E3 ubiquitin ligase 4provided by HGNC Primary source HGNC:HGNC:29151 See related Ensembl:ENSG00000110042 MIM:616110; AllianceGenome:HGNC:29151 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF155 Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in urinary bladder (RPKM 13.0), lung (RPKM 11.7) and 25 other tissues See more Orthologs mouse all
DTYMK, Official Symbol DTYMKprovided by HGNC Official Full Name deoxythymidylate kinaseprovided by HGNC Primary source HGNC:HGNC:3061 See related Ensembl:ENSG00000168393 MIM:188345; AllianceGenome:HGNC:3061 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDC8; TMPK; TYMK; CONPM; PP3731 Summary Enables thymidylate kinase activity. Predicted to be involved in dTDP biosynthetic process; dTTP biosynthetic process; and dUDP biosynthetic process. Predicted to act upstream of or within cellular response to growth factor stimulus and nucleotide biosynthetic process. Predicted to be located in mitochondrial intermembrane space and mitochondrial matrix. Predicted to be active in cytosol; mitochondrion; and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 9.1), lymph node (RPKM 8.0) and 25 other tissues See more Orthologs mouse all
DUBR, Official Symbol DUBRprovided by HGNC Official Full Name DPPA2 upstream binding RNAprovided by HGNC Primary source HGNC:HGNC:48569 See related Ensembl:ENSG00000243701 MIM:616619; AllianceGenome:HGNC:48569 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUM; LINC0883; LINC00883 Summary Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of myoblast differentiation; and regulation of DNA methylation. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in ovary (RPKM 6.4), testis (RPKM 4.8) and 22 other tissues See more Orthologs mouse all
DUOX1, Official Symbol DUOX1provided by HGNC Official Full Name dual oxidase 1provided by HGNC Primary source HGNC:HGNC:3062 See related Ensembl:ENSG00000137857 MIM:606758; AllianceGenome:HGNC:3062 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LNOX1; THOX1; NOXEF1 Summary The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012] Expression Biased expression in skin (RPKM 27.3), thyroid (RPKM 26.8) and 8 other tissues See more Orthologs mouse all
DUOX2, Official Symbol DUOX2provided by HGNC Official Full Name dual oxidase 2provided by HGNC Primary source HGNC:HGNC:13273 See related Ensembl:ENSG00000140279 MIM:606759; AllianceGenome:HGNC:13273 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TDH6; LNOX2; THOX2; NOXEF2; P138-TOX Summary The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008] Expression Biased expression in gall bladder (RPKM 216.4), thyroid (RPKM 55.7) and 3 other tissues See more Orthologs mouse all
DUOXA1, Official Symbol DUOXA1provided by HGNC Official Full Name dual oxidase maturation factor 1provided by HGNC Primary source HGNC:HGNC:26507 See related Ensembl:ENSG00000140254 MIM:612771; AllianceGenome:HGNC:26507 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIP; mol; NUMBIP Summary Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] Expression Biased expression in esophagus (RPKM 22.8), skin (RPKM 19.6) and 7 other tissues See more Orthologs mouse all
DUOXA2, Official Symbol DUOXA2provided by HGNC Official Full Name dual oxidase maturation factor 2provided by HGNC Primary source HGNC:HGNC:32698 See related Ensembl:ENSG00000140274 MIM:612772; AllianceGenome:HGNC:32698 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TDH5; SIMNIPHOM Summary This gene encodes an endoplasmic reticulum protein that is necessary for proper cellular localization and maturation of functional dual oxidase 2. Mutations in this gene have been associated with thyroid dyshormonogenesis 5.[provided by RefSeq, Feb 2010] Expression Biased expression in gall bladder (RPKM 85.0), urinary bladder (RPKM 21.8) and 5 other tissues See more Orthologs mouse all
DUS1L, Official Symbol DUS1Lprovided by HGNC Official Full Name dihydrouridine synthase 1 likeprovided by HGNC Primary source HGNC:HGNC:30086 See related Ensembl:ENSG00000169718 AllianceGenome:HGNC:30086 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUS1; PP3111 Summary Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 23.4), prostate (RPKM 22.1) and 25 other tissues See more Orthologs mouse all
DUS2, Official Symbol DUS2provided by HGNC Official Full Name dihydrouridine synthase 2provided by HGNC Primary source HGNC:HGNC:26014 See related Ensembl:ENSG00000167264 MIM:609707; AllianceGenome:HGNC:26014 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMM1; DUS2L; URLC8 Summary This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012] Expression Broad expression in testis (RPKM 12.7), lymph node (RPKM 5.7) and 24 other tissues See more Orthologs mouse all
DUS3L, Official Symbol DUS3Lprovided by HGNC Official Full Name dihydrouridine synthase 3 likeprovided by HGNC Primary source HGNC:HGNC:26920 See related Ensembl:ENSG00000141994 AllianceGenome:HGNC:26920 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUS3 Summary Enables RNA binding activity. Predicted to be involved in tRNA dihydrouridine synthesis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 13.5), bone marrow (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
DUS4L, Official Symbol DUS4Lprovided by HGNC Official Full Name dihydrouridine synthase 4 likeprovided by HGNC Primary source HGNC:HGNC:21517 See related Ensembl:ENSG00000105865 AllianceGenome:HGNC:21517 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUS4; PP35 Summary Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.2), testis (RPKM 2.8) and 25 other tissues See more Orthologs mouse all
DUS4L-BCAP29, Official Symbol DUS4L-BCAP29provided by HGNC Official Full Name DUS4L-BCAP29 readthroughprovided by HGNC Primary source HGNC:HGNC:54422 See related Ensembl:ENSG00000288558 AllianceGenome:HGNC:54422 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring readthrough transcription between the neighboring DUS4L (dihydrouridine synthase 4 like) and BCAP29 (B cell receptor associated protein 29) genes on chromosome 7. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2019] Orthologs all
DUSP1, Official Symbol DUSP1provided by HGNC Official Full Name dual specificity phosphatase 1provided by HGNC Primary source HGNC:HGNC:3064 See related Ensembl:ENSG00000120129 MIM:600714; AllianceGenome:HGNC:3064 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HVH1; MKP1; CL100; MKP-1; PTPN10 Summary The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in gall bladder (RPKM 359.2), prostate (RPKM 315.6) and 24 other tissues See more Orthologs mouse all
DUSP10, Official Symbol DUSP10provided by HGNC Official Full Name dual specificity phosphatase 10provided by HGNC Primary source HGNC:HGNC:3065 See related Ensembl:ENSG00000143507 MIM:608867; AllianceGenome:HGNC:3065 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP5; MKP-5 Summary Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] Expression Broad expression in liver (RPKM 11.1), bone marrow (RPKM 10.7) and 22 other tissues See more Orthologs mouse all
DUSP11, Official Symbol DUSP11provided by HGNC Official Full Name dual specificity phosphatase 11provided by HGNC Primary source HGNC:HGNC:3066 See related Ensembl:ENSG00000144048 MIM:603092; AllianceGenome:HGNC:3066 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIR1 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008] Expression Ubiquitous expression in esophagus (RPKM 14.8), urinary bladder (RPKM 12.3) and 25 other tissues See more Orthologs mouse all
DUSP12, Official Symbol DUSP12provided by HGNC Official Full Name dual specificity phosphatase 12provided by HGNC Primary source HGNC:HGNC:3067 See related Ensembl:ENSG00000081721 MIM:604835; AllianceGenome:HGNC:3067 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YVH1; DUSP1 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 12.0), lymph node (RPKM 7.7) and 25 other tissues See more Orthologs mouse all
DUSP12P1, Official Symbol DUSP12P1provided by HGNC Official Full Name dual specificity phosphatase 12 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49059 See related Ensembl:ENSG00000277000 AllianceGenome:HGNC:49059 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
DUSP13B, Official Symbol DUSP13Bprovided by HGNC Official Full Name dual specificity phosphatase 13Bprovided by HGNC Primary source HGNC:HGNC:19681 See related Ensembl:ENSG00000079393 MIM:613191; AllianceGenome:HGNC:19681 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDSP; TMDP; SKRP4; DUSP13 Summary Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This gene encodes a dual specificity phosphatase that acts on both phosphotyrosine and phosphoserine/threonine residues. The encoded protein is expressed in testis. [provided by RefSeq, Mar 2023] Expression Biased expression in testis (RPKM 6.3), heart (RPKM 1.5) and 3 other tissues See more Orthologs mouse all
DUSP14, Official Symbol DUSP14provided by HGNC Official Full Name dual specificity phosphatase 14provided by HGNC Primary source HGNC:HGNC:17007 See related Ensembl:ENSG00000276023 MIM:606618; AllianceGenome:HGNC:17007 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP6; MKP-L Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Expression Broad expression in thyroid (RPKM 9.3), skin (RPKM 8.7) and 24 other tissues See more Orthologs mouse all
DUSP15, Official Symbol DUSP15provided by HGNC Official Full Name dual specificity phosphatase 15provided by HGNC Primary source HGNC:HGNC:16236 See related Ensembl:ENSG00000149599 MIM:616776; AllianceGenome:HGNC:16236 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VHY; C20orf57 Summary The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Biased expression in testis (RPKM 10.5), kidney (RPKM 3.2) and 1 other tissue See more Orthologs mouse all
DUSP16, Official Symbol DUSP16provided by HGNC Official Full Name dual specificity phosphatase 16provided by HGNC Primary source HGNC:HGNC:17909 See related Ensembl:ENSG00000111266 MIM:607175; AllianceGenome:HGNC:17909 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP7; MKP-7 Summary This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010] Expression Ubiquitous expression in adrenal (RPKM 19.6), liver (RPKM 13.0) and 25 other tissues See more Orthologs mouse all
DUSP18, Official Symbol DUSP18provided by HGNC Official Full Name dual specificity phosphatase 18provided by HGNC Primary source HGNC:HGNC:18484 See related Ensembl:ENSG00000167065 MIM:611446; AllianceGenome:HGNC:18484 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DSP18; DUSP20; LMWDSP20 Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Expression Broad expression in testis (RPKM 4.3), lung (RPKM 2.8) and 24 other tissues See more Orthologs mouse all
DUSP19, Official Symbol DUSP19provided by HGNC Official Full Name dual specificity phosphatase 19provided by HGNC Primary source HGNC:HGNC:18894 See related Ensembl:ENSG00000162999 MIM:611437; AllianceGenome:HGNC:18894 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SKRP1; DUSP17; LMWDSP3; TS-DSP1 Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all
DUSP2, Official Symbol DUSP2provided by HGNC Official Full Name dual specificity phosphatase 2provided by HGNC Primary source HGNC:HGNC:3068 See related Ensembl:ENSG00000158050 MIM:603068; AllianceGenome:HGNC:3068 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAC1; PAC-1 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 49.4), lymph node (RPKM 22.5) and 9 other tissues See more Orthologs mouse all
DUSP21, Official Symbol DUSP21provided by HGNC Official Full Name dual specificity phosphatase 21provided by HGNC Primary source HGNC:HGNC:20476 See related Ensembl:ENSG00000189037 MIM:300678; AllianceGenome:HGNC:20476 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LMWDSP21 Summary This gene encodes a member of the dual specificity phosphatase family, specifically the low molecular weight dual specificity phosphatase family. The encoded protein localizes to both the cytoplasm and the nucleus and functions to remove phosphate groups from phosphotyrosine and phosphothreonine residues.[provided by RefSeq, Mar 2009] Orthologs mouse all
DUSP22, Official Symbol DUSP22provided by HGNC Official Full Name dual specificity phosphatase 22provided by HGNC Primary source HGNC:HGNC:16077 See related Ensembl:ENSG00000112679 MIM:616778; AllianceGenome:HGNC:16077 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2 Summary Enables non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in plasma membrane. Part of cytoplasm; filamentous actin; and leading edge of lamellipodium. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 10.7), spleen (RPKM 5.4) and 25 other tissues See more Orthologs mouse all
DUSP23, Official Symbol DUSP23provided by HGNC Official Full Name dual specificity phosphatase 23provided by HGNC Primary source HGNC:HGNC:21480 See related Ensembl:ENSG00000158716 MIM:618361; AllianceGenome:HGNC:21480 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VHZ; LDP3; MOSP; LDP-3; DUSP25 Summary Enables protein tyrosine/serine/threonine phosphatase activity. Involved in dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 18.6), liver (RPKM 13.3) and 25 other tissues See more Orthologs mouse all
DUSP26, Official Symbol DUSP26provided by HGNC Official Full Name dual specificity phosphatase 26provided by HGNC Primary source HGNC:HGNC:28161 See related Ensembl:ENSG00000133878 MIM:618368; AllianceGenome:HGNC:28161 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LDP4; MKP8; NEAP; DSP-4; LDP-4; MKP-8; NATA1; SKRP3; DUSP24 Summary This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Expression Biased expression in heart (RPKM 15.4), brain (RPKM 12.7) and 8 other tissues See more Orthologs mouse all
DUSP28, Official Symbol DUSP28provided by HGNC Official Full Name dual specificity phosphatase 28provided by HGNC Primary source HGNC:HGNC:33237 See related Ensembl:ENSG00000188542 AllianceGenome:HGNC:33237 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VHP; DUSP26 Summary Enables phosphatase activity. Involved in dephosphorylation. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 1.8), bone marrow (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
DUSP29, Official Symbol DUSP29provided by HGNC Official Full Name dual specificity phosphatase 29provided by HGNC Primary source HGNC:HGNC:23481 See related Ensembl:ENSG00000188716 MIM:618574; AllianceGenome:HGNC:23481 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUPD1; FMDSP; DUSP27 Summary Enables protein homodimerization activity and protein tyrosine/serine/threonine phosphatase activity. Involved in protein dephosphorylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
DUSP3, Official Symbol DUSP3provided by HGNC Official Full Name dual specificity phosphatase 3provided by HGNC Primary source HGNC:HGNC:3069 See related Ensembl:ENSG00000108861 MIM:600183; AllianceGenome:HGNC:3069 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VHR Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 57.5), esophagus (RPKM 29.0) and 25 other tissues See more Orthologs mouse all
DUSP4, Official Symbol DUSP4provided by HGNC Official Full Name dual specificity phosphatase 4provided by HGNC Primary source HGNC:HGNC:3070 See related Ensembl:ENSG00000120875 MIM:602747; AllianceGenome:HGNC:3070 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TYP; HVH2; MKP2; MKP-2 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008] Expression Broad expression in stomach (RPKM 8.5), gall bladder (RPKM 5.0) and 19 other tissues See more Orthologs mouse all
DUSP5, Official Symbol DUSP5provided by HGNC Official Full Name dual specificity phosphatase 5provided by HGNC Primary source HGNC:HGNC:3071 See related Ensembl:ENSG00000138166 MIM:603069; AllianceGenome:HGNC:3071 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUSP; HVH3 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 53.4), gall bladder (RPKM 35.1) and 22 other tissues See more Orthologs mouse all
DUSP5-DT, Official Symbol DUSP5-DTprovided by HGNC Official Full Name DUSP5 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:55154 See related AllianceGenome:HGNC:55154 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
DUSP6, Official Symbol DUSP6provided by HGNC Official Full Name dual specificity phosphatase 6provided by HGNC Primary source HGNC:HGNC:3072 See related Ensembl:ENSG00000139318 MIM:602748; AllianceGenome:HGNC:3072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HH19; MKP3; PYST1 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] Expression Ubiquitous expression in bone marrow (RPKM 46.5), fat (RPKM 44.7) and 24 other tissues See more Orthologs mouse all
DUSP7, Official Symbol DUSP7provided by HGNC Official Full Name dual specificity phosphatase 7provided by HGNC Primary source HGNC:HGNC:3073 See related Ensembl:ENSG00000164086 MIM:602749; AllianceGenome:HGNC:3073 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKPX; PYST2 Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Expression Ubiquitous expression in esophagus (RPKM 18.5), skin (RPKM 16.3) and 24 other tissues See more Orthologs mouse all
DUSP8, Official Symbol DUSP8provided by HGNC Official Full Name dual specificity phosphatase 8provided by HGNC Primary source HGNC:HGNC:3074 See related Ensembl:ENSG00000184545 MIM:602038; AllianceGenome:HGNC:3074 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HB5; HVH8; HVH-5; C11orf81 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 9.1), colon (RPKM 3.4) and 22 other tissues See more Orthologs mouse all
DUSP8P2, Official Symbol DUSP8P2provided by HGNC Official Full Name dual specificity phosphatase 8 pseudogene 2provided by HGNC Primary source HGNC:HGNC:45001 See related AllianceGenome:HGNC:45001 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUSP8P4
DUSP8P5, Official Symbol DUSP8P5provided by HGNC Official Full Name dual specificity phosphatase 8 pseudogene 5provided by HGNC Primary source HGNC:HGNC:45003 See related AllianceGenome:HGNC:45003 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
DUSP9, Official Symbol DUSP9provided by HGNC Official Full Name dual specificity phosphatase 9provided by HGNC Primary source HGNC:HGNC:3076 See related Ensembl:ENSG00000130829 MIM:300134; AllianceGenome:HGNC:3076 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP4; MKP-4 Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Biased expression in placenta (RPKM 41.7) and kidney (RPKM 21.4) See more Orthologs mouse all
DUT, Official Symbol DUTprovided by HGNC Official Full Name deoxyuridine triphosphataseprovided by HGNC Primary source HGNC:HGNC:3078 See related Ensembl:ENSG00000128951 MIM:601266; AllianceGenome:HGNC:3078 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMFDMS; dUTPase Summary This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 16.5), lymph node (RPKM 14.4) and 25 other tissues See more Orthologs mouse all
DUTP1, Official Symbol DUTP1provided by HGNC Official Full Name deoxyuridine triphosphatase pseudogene 1provided by HGNC Primary source HGNC:HGNC:31956 See related AllianceGenome:HGNC:31956 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUTL
DUTP2, Official Symbol DUTP2provided by HGNC Official Full Name deoxyuridine triphosphatase pseudogene 2provided by HGNC Primary source HGNC:HGNC:39515 See related AllianceGenome:HGNC:39515 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
DUTP3, Official Symbol DUTP3provided by HGNC Official Full Name deoxyuridine triphosphatase pseudogene 3provided by HGNC Primary source HGNC:HGNC:39516 See related Ensembl:ENSG00000226857 AllianceGenome:HGNC:39516 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
DUTP4, Official Symbol DUTP4provided by HGNC Official Full Name deoxyuridine triphosphatase pseudogene 4provided by HGNC Primary source HGNC:HGNC:39517 See related Ensembl:ENSG00000229829 AllianceGenome:HGNC:39517 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo