psui3905/ncbi_genes_summary huggingface dataset:
FDPSP6, Official Symbol FDPSP6provided by HGNC Official Full Name farnesyl diphosphate synthase pseudogene 6provided by HGNC Primary source HGNC:HGNC:3637 See related Ensembl:ENSG00000233676 AllianceGenome:HGNC:3637 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FDPSP
FDPSP7, Official Symbol FDPSP7provided by HGNC Official Full Name farnesyl diphosphate synthase pseudogene 7provided by HGNC Primary source HGNC:HGNC:33487 See related Ensembl:ENSG00000231087 AllianceGenome:HGNC:33487 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FDPSL2B
FDPSP8, Official Symbol FDPSP8provided by HGNC Official Full Name farnesyl diphosphate synthase pseudogene 8provided by HGNC Primary source HGNC:HGNC:39085 See related Ensembl:ENSG00000224763 AllianceGenome:HGNC:39085 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
FDX1, Official Symbol FDX1provided by HGNC Official Full Name ferredoxin 1provided by HGNC Primary source HGNC:HGNC:3638 See related Ensembl:ENSG00000137714 MIM:103260; AllianceGenome:HGNC:3638 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADX; FDX; LOH11CR1D Summary This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011] Expression Biased expression in adrenal (RPKM 178.6), kidney (RPKM 13.5) and 5 other tissues See more Orthologs mouse all
FDX2, Official Symbol FDX2provided by HGNC Official Full Name ferredoxin 2provided by HGNC Primary source HGNC:HGNC:30546 See related Ensembl:ENSG00000267673 MIM:614585; AllianceGenome:HGNC:30546 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FDX1L; MEOAL Summary This gene encodes a member of the ferredoxin family. The encoded protein contains a 2Fe-2S ferredoxin-type domain and is essential for heme A and Fe/S protein biosynthesis. Mutation in FDX1L gene is associated with mitochondrial muscle myopathy. [provided by RefSeq, Sep 2014] Expression Ubiquitous expression in brain (RPKM 12.1), thyroid (RPKM 8.3) and 25 other tissues See more Orthologs mouse all
FDXACB1, Official Symbol FDXACB1provided by HGNC Official Full Name ferredoxin-fold anticodon binding domain containing 1provided by HGNC Primary source HGNC:HGNC:25110 See related Ensembl:ENSG00000255561 AllianceGenome:HGNC:25110 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hCG_2033039 Summary This gene encodes a protein which contains a ferredoxin-fold anticodon-binding domain which is contained in a subset of phenylalanyl tRNA synthetases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Broad expression in testis (RPKM 3.2), lymph node (RPKM 1.6) and 24 other tissues See more Orthologs mouse all
FDXR, Official Symbol FDXRprovided by HGNC Official Full Name ferredoxin reductaseprovided by HGNC Primary source HGNC:HGNC:3642 See related Ensembl:ENSG00000161513 MIM:103270; AllianceGenome:HGNC:3642 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADR; ADXR; ANOA Summary This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in adrenal (RPKM 75.2), testis (RPKM 17.3) and 5 other tissues See more Orthologs mouse all
FECH, Official Symbol FECHprovided by HGNC Official Full Name ferrochelataseprovided by HGNC Primary source HGNC:HGNC:3647 See related Ensembl:ENSG00000066926 MIM:612386; AllianceGenome:HGNC:3647 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPP; FCE; EPP1 Summary The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010] Expression Broad expression in bone marrow (RPKM 19.5), kidney (RPKM 8.4) and 24 other tissues See more Orthologs mouse all
FEM1A, Official Symbol FEM1Aprovided by HGNC Official Full Name fem-1 homolog Aprovided by HGNC Primary source HGNC:HGNC:16934 See related Ensembl:ENSG00000141965 MIM:613538; AllianceGenome:HGNC:16934 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPRAP Summary Enables EP4 subtype prostaglandin E2 receptor binding activity and ubiquitin ligase-substrate adaptor activity. Involved in negative regulation of inflammatory response and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Part of Cul2-RING ubiquitin ligase complex. Is active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
FEM1AP1, Official Symbol FEM1AP1provided by HGNC Official Full Name fem-1 homolog A pseudogene 1provided by HGNC Primary source HGNC:HGNC:17219 See related Ensembl:ENSG00000229231 AllianceGenome:HGNC:17219 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEM1DP
FEM1AP2, Official Symbol FEM1AP2provided by HGNC Official Full Name fem-1 homolog A pseudogene 2provided by HGNC Primary source HGNC:HGNC:39830 See related Ensembl:ENSG00000265296 AllianceGenome:HGNC:39830 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
FEM1AP3, Official Symbol FEM1AP3provided by HGNC Official Full Name fem-1 homolog A pseudogene 3provided by HGNC Primary source HGNC:HGNC:39831 See related Ensembl:ENSG00000217770 AllianceGenome:HGNC:39831 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
FEM1B, Official Symbol FEM1Bprovided by HGNC Official Full Name fem-1 homolog Bprovided by HGNC Primary source HGNC:HGNC:3649 See related Ensembl:ENSG00000169018 MIM:613539; AllianceGenome:HGNC:3649 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as F1AA; F1A-ALPHA; FEM1-beta Summary This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in brain (RPKM 18.1), endometrium (RPKM 14.9) and 25 other tissues See more Orthologs mouse all
FEM1C, Official Symbol FEM1Cprovided by HGNC Official Full Name fem-1 homolog Cprovided by HGNC Primary source HGNC:HGNC:16933 See related Ensembl:ENSG00000145780 MIM:608767; AllianceGenome:HGNC:16933 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEM1A; EUROIMAGE686608; EUROIMAGE783647 Summary Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in cytosol and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 24.9), testis (RPKM 9.4) and 25 other tissues See more Orthologs mouse all
FEN1, Official Symbol FEN1provided by HGNC Official Full Name flap structure-specific endonuclease 1provided by HGNC Primary source HGNC:HGNC:3650 See related Ensembl:ENSG00000168496 MIM:600393; AllianceGenome:HGNC:3650 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MF1; RAD2; FEN-1 Summary The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 16.0), bone marrow (RPKM 13.0) and 24 other tissues See more Orthologs mouse all
FENDRR, Official Symbol FENDRRprovided by HGNC Official Full Name FOXF1 adjacent non-coding developmental regulatory RNAprovided by HGNC Primary source HGNC:HGNC:43894 See related Ensembl:ENSG00000268388 MIM:614975; AllianceGenome:HGNC:43894 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FOXF1AS1; FOXF1-AS1; lincFOXF1; TCONS_00024240; onco-lncRNA-21 Summary This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] Expression Biased expression in lung (RPKM 13.0), urinary bladder (RPKM 9.3) and 9 other tissues See more Orthologs mouse all
FER, Official Symbol FERprovided by HGNC Official Full Name FER tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:3655 See related Ensembl:ENSG00000151422 MIM:176942; AllianceGenome:HGNC:3655 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TYK3; PPP1R74; p94-Fer Summary The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015] Expression Ubiquitous expression in thyroid (RPKM 2.8), testis (RPKM 2.2) and 25 other tissues See more Orthologs mouse all
FER1L4, Official Symbol FER1L4provided by HGNC Official Full Name fer-1 like family member 4 (pseudogene)provided by HGNC Primary source HGNC:HGNC:15801 See related Ensembl:ENSG00000088340 AllianceGenome:HGNC:15801 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf124 Summary Predicted to enable metal ion binding activity. Predicted to be involved in plasma membrane organization. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in stomach (RPKM 27.2), urinary bladder (RPKM 7.3) and 4 other tissues See more
FER1L5, Official Symbol FER1L5provided by HGNC Official Full Name fer-1 like family member 5provided by HGNC Primary source HGNC:HGNC:19044 See related Ensembl:ENSG00000249715 AllianceGenome:HGNC:19044 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; negative regulation of phagocytosis; and plasma membrane organization. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in T-tubule and cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 3.3) and prostate (RPKM 0.1) See more Orthologs mouse all
FER1L6, Official Symbol FER1L6provided by HGNC Official Full Name fer-1 like family member 6provided by HGNC Primary source HGNC:HGNC:28065 See related Ensembl:ENSG00000214814 AllianceGenome:HGNC:28065 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8ORFK23 Summary Predicted to enable metal ion binding activity. Predicted to be involved in plasma membrane organization. Predicted to act upstream of or within response to bacterium. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in stomach (RPKM 17.6), colon (RPKM 3.5) and 5 other tissues See more Orthologs mouse all
FER1L6-AS1, Official Symbol FER1L6-AS1provided by HGNC Official Full Name FER1L6 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:26652 See related Ensembl:ENSG00000181171 AllianceGenome:HGNC:26652 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8orf54 Expression Low expression observed in reference dataset See more
FER1L6-AS2, Official Symbol FER1L6-AS2provided by HGNC Official Full Name FER1L6 antisense RNA 2provided by HGNC Primary source HGNC:HGNC:26534 See related Ensembl:ENSG00000253868 AllianceGenome:HGNC:26534 Gene type ncRNA RefSeq status PREDICTED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8orf78 Expression Biased expression in stomach (RPKM 3.2), testis (RPKM 2.8) and 6 other tissues See more
FERD3L, Official Symbol FERD3Lprovided by HGNC Official Full Name Fer3 like bHLH transcription factorprovided by HGNC Primary source HGNC:HGNC:16660 See related Ensembl:ENSG00000146618 MIM:617578; AllianceGenome:HGNC:16660 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTFB; NATO3; NTWIST; N-TWIST; bHLHa31 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in developmental process; negative regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell development; floor plate development; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
FERMT1, Official Symbol FERMT1provided by HGNC Official Full Name FERM domain containing kindlin 1provided by HGNC Primary source HGNC:HGNC:15889 See related Ensembl:ENSG00000101311 MIM:607900; AllianceGenome:HGNC:15889 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as URP1; KIND1; DTGCU2; UNC112A; C20orf42 Summary This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. [provided by RefSeq, Dec 2009] Expression Broad expression in colon (RPKM 18.0), skin (RPKM 10.5) and 15 other tissues See more Orthologs mouse all
FERMT2, Official Symbol FERMT2provided by HGNC Official Full Name FERM domain containing kindlin 2provided by HGNC Primary source HGNC:HGNC:15767 See related Ensembl:ENSG00000073712 MIM:607746; AllianceGenome:HGNC:15767 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B Summary Enables several functions, including actin binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol; focal adhesion; and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 84.8), endometrium (RPKM 56.1) and 22 other tissues See more Orthologs mouse all
FERMT3, Official Symbol FERMT3provided by HGNC Official Full Name FERM domain containing kindlin 3provided by HGNC Primary source HGNC:HGNC:23151 See related Ensembl:ENSG00000149781 MIM:607901; AllianceGenome:HGNC:23151 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as URP2; KIND3; MIG-2; MIG2B; URP2SF; UNC112C Summary Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010] Expression Broad expression in bone marrow (RPKM 48.7), spleen (RPKM 38.0) and 15 other tissues See more Orthologs mouse all
FERP1, Official Symbol FERP1provided by HGNC Official Full Name FER tyrosine kinase pseudogene 1provided by HGNC Primary source HGNC:HGNC:26443 See related Ensembl:ENSG00000232149 AllianceGenome:HGNC:26443 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FERP; FERps
FES, Official Symbol FESprovided by HGNC Official Full Name FES proto-oncogene, tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:3657 See related Ensembl:ENSG00000182511 MIM:190030; AllianceGenome:HGNC:3657 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FPS Summary This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009] Expression Broad expression in spleen (RPKM 39.1), bone marrow (RPKM 25.6) and 23 other tissues See more Orthologs mouse all
FETUB, Official Symbol FETUBprovided by HGNC Official Full Name fetuin Bprovided by HGNC Primary source HGNC:HGNC:3658 See related Ensembl:ENSG00000090512 MIM:605954; AllianceGenome:HGNC:3658 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 16G2; Gugu; IRL685 Summary The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008] Expression Restricted expression toward liver (RPKM 42.7) See more Orthologs mouse all
FEV, Official Symbol FEVprovided by HGNC Official Full Name FEV transcription factor, ETS family memberprovided by HGNC Primary source HGNC:HGNC:18562 See related Ensembl:ENSG00000163497 MIM:607150; AllianceGenome:HGNC:18562 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PET-1; HSRNAFEV Summary This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008] Expression Biased expression in duodenum (RPKM 1.5), stomach (RPKM 1.5) and 5 other tissues See more Orthologs mouse all
FEZ1, Official Symbol FEZ1provided by HGNC Official Full Name fasciculation and elongation protein zeta 1provided by HGNC Primary source HGNC:HGNC:3659 See related Ensembl:ENSG00000149557 MIM:604825; AllianceGenome:HGNC:3659 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNC-76 Summary This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 74.3), urinary bladder (RPKM 9.7) and 4 other tissues See more Orthologs mouse all
FEZ2, Official Symbol FEZ2provided by HGNC Official Full Name fasciculation and elongation protein zeta 2provided by HGNC Primary source HGNC:HGNC:3660 See related Ensembl:ENSG00000171055 MIM:604826; AllianceGenome:HGNC:3660 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HUM3CL Summary This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 32.7), brain (RPKM 29.1) and 24 other tissues See more Orthologs mouse all
FEZF1, Official Symbol FEZF1provided by HGNC Official Full Name FEZ family zinc finger 1provided by HGNC Primary source HGNC:HGNC:22788 See related Ensembl:ENSG00000128610 MIM:613301; AllianceGenome:HGNC:22788 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEZ; HH22; ZNF312B Summary This gene encodes a transcriptional repressor that belongs to the zinc finger double domain protein family. The encoded protein is thought to play a role in the embryonic migration of gonadotropin-releasing hormone neurons into the brain. Mutations in this gene are associated with hypogonadotropic hypogonadism-22 with anosmia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] Expression Restricted expression toward testis (RPKM 1.2) See more Orthologs mouse all
FEZF1-AS1, Official Symbol FEZF1-AS1provided by HGNC Official Full Name FEZF1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41001 See related Ensembl:ENSG00000230316 AllianceGenome:HGNC:41001 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
FEZF2, Official Symbol FEZF2provided by HGNC Official Full Name FEZ family zinc finger 2provided by HGNC Primary source HGNC:HGNC:13506 See related Ensembl:ENSG00000153266 MIM:607414; AllianceGenome:HGNC:13506 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEZ; TOF; FEZL; FKSG36; ZFP312; ZNF312 Summary Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and regulation of neuron differentiation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 4.1) See more Orthologs mouse all
FFAR1, Official Symbol FFAR1provided by HGNC Official Full Name free fatty acid receptor 1provided by HGNC Primary source HGNC:HGNC:4498 See related Ensembl:ENSG00000126266 MIM:603820; AllianceGenome:HGNC:4498 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FFA1R; GPR40; GPCR40 Summary This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009] Orthologs mouse all
FFAR2, Official Symbol FFAR2provided by HGNC Official Full Name free fatty acid receptor 2provided by HGNC Primary source HGNC:HGNC:4501 See related Ensembl:ENSG00000126262 MIM:603823; AllianceGenome:HGNC:4501 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FFA2R; GPR43 Summary This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009] Expression Biased expression in appendix (RPKM 7.9), bone marrow (RPKM 5.6) and 11 other tissues See more Orthologs mouse all
FFAR3, Official Symbol FFAR3provided by HGNC Official Full Name free fatty acid receptor 3provided by HGNC Primary source HGNC:HGNC:4499 See related Ensembl:ENSG00000185897 MIM:603821; AllianceGenome:HGNC:4499 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FFA3R; GPR41; GPR42 Summary Enables G protein-coupled receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and cellular response to fatty acid. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in appendix (RPKM 1.2), fat (RPKM 0.6) and 13 other tissues See more Orthologs mouse all
FFAR4, Official Symbol FFAR4provided by HGNC Official Full Name free fatty acid receptor 4provided by HGNC Primary source HGNC:HGNC:19061 See related Ensembl:ENSG00000186188 MIM:609044; AllianceGenome:HGNC:19061 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GT01; PGR4; OB10Q; BMIQ10; GPR120; GPR129; O3FAR1 Summary This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] Expression Biased expression in colon (RPKM 6.8), fat (RPKM 2.6) and 2 other tissues See more Orthologs mouse all
FGA, Official Symbol FGAprovided by HGNC Official Full Name fibrinogen alpha chainprovided by HGNC Primary source HGNC:HGNC:3661 See related Ensembl:ENSG00000171560 MIM:134820; AllianceGenome:HGNC:3661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fib2 Summary This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016] Expression Restricted expression toward liver (RPKM 2863.0) See more Orthologs mouse all
FGB, Official Symbol FGBprovided by HGNC Official Full Name fibrinogen beta chainprovided by HGNC Primary source HGNC:HGNC:3662 See related Ensembl:ENSG00000171564 MIM:134830; AllianceGenome:HGNC:3662 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEL-S-78p Summary The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Aug 2020] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for disease process. Expression Restricted expression toward liver (RPKM 2456.5) See more Orthologs mouse all
FGD1, Official Symbol FGD1provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 1provided by HGNC Primary source HGNC:HGNC:3663 See related Ensembl:ENSG00000102302 MIM:300546; AllianceGenome:HGNC:3663 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAS; FGDY; MRXS16; ZFYVE3 Summary This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in endometrium (RPKM 4.2), brain (RPKM 3.6) and 25 other tissues See more Orthologs mouse all
FGD2, Official Symbol FGD2provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 2provided by HGNC Primary source HGNC:HGNC:3664 See related Ensembl:ENSG00000146192 MIM:605091; AllianceGenome:HGNC:3664 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE4 Summary The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016] Expression Biased expression in spleen (RPKM 19.9), lymph node (RPKM 9.1) and 13 other tissues See more Orthologs mouse all
FGD3, Official Symbol FGD3provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 3provided by HGNC Primary source HGNC:HGNC:16027 See related Ensembl:ENSG00000127084 MIM:617554; AllianceGenome:HGNC:16027 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE5 Summary Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 16.0), lymph node (RPKM 14.2) and 17 other tissues See more Orthologs mouse all
FGD4, Official Symbol FGD4provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 4provided by HGNC Primary source HGNC:HGNC:19125 See related Ensembl:ENSG00000139132 MIM:611104; AllianceGenome:HGNC:19125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMT4H; FRABP; ZFYVE6 Summary This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] Expression Ubiquitous expression in ovary (RPKM 8.0), stomach (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
FGD5, Official Symbol FGD5provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 5provided by HGNC Primary source HGNC:HGNC:19117 See related Ensembl:ENSG00000154783 MIM:614788; AllianceGenome:HGNC:19117 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE23 Summary Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 15.9), lung (RPKM 13.8) and 22 other tissues See more Orthologs mouse all
FGD5-AS1, Official Symbol FGD5-AS1provided by HGNC Official Full Name FGD5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40410 See related Ensembl:ENSG00000225733 AllianceGenome:HGNC:40410 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in brain (RPKM 37.5), thyroid (RPKM 37.4) and 25 other tissues See more
FGD5P1, Official Symbol FGD5P1provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 5 pseudogene 1provided by HGNC Primary source HGNC:HGNC:44498 See related Ensembl:ENSG00000290338 AllianceGenome:HGNC:44498 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 1.4), ovary (RPKM 0.2) and 5 other tissues See more
FGD6, Official Symbol FGD6provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 6provided by HGNC Primary source HGNC:HGNC:21740 See related Ensembl:ENSG00000180263 MIM:613520; AllianceGenome:HGNC:21740 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE24 Summary Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 3.9), gall bladder (RPKM 3.5) and 25 other tissues See more Orthologs mouse all
FGF1, Official Symbol FGF1provided by HGNC Official Full Name fibroblast growth factor 1provided by HGNC Primary source HGNC:HGNC:3665 See related Ensembl:ENSG00000113578 MIM:131220; AllianceGenome:HGNC:3665 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009] Expression Biased expression in brain (RPKM 36.0), kidney (RPKM 21.0) and 4 other tissues See more Orthologs mouse all
FGF10, Official Symbol FGF10provided by HGNC Official Full Name fibroblast growth factor 10provided by HGNC Primary source HGNC:HGNC:3666 See related Ensembl:ENSG00000070193 MIM:602115; AllianceGenome:HGNC:3666 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LADD3 Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008] Expression Broad expression in ovary (RPKM 9.2), fat (RPKM 4.7) and 15 other tissues See more Orthologs mouse all
FGF10-AS1, Official Symbol FGF10-AS1provided by HGNC Official Full Name FGF10 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:49382 See related Ensembl:ENSG00000248464 AllianceGenome:HGNC:49382 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in ovary (RPKM 1.3), fat (RPKM 0.9) and 15 other tissues See more
FGF11, Official Symbol FGF11provided by HGNC Official Full Name fibroblast growth factor 11provided by HGNC Primary source HGNC:HGNC:3667 See related Ensembl:ENSG00000161958 MIM:601514; AllianceGenome:HGNC:3667 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FHF3; FHF-3; FGF-11 Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Broad expression in adrenal (RPKM 9.9), skin (RPKM 7.0) and 14 other tissues See more Orthologs mouse all