psui3905/ncbi_genes_summary huggingface dataset:
BMP3, Official Symbol BMP3provided by HGNC Official Full Name bone morphogenetic protein 3provided by HGNC Primary source HGNC:HGNC:1070 See related Ensembl:ENSG00000152785 MIM:112263; AllianceGenome:HGNC:1070 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMP-3A Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016] Expression Biased expression in urinary bladder (RPKM 12.1), colon (RPKM 5.2) and 5 other tissues See more Orthologs mouse all
BMP4, Official Symbol BMP4provided by HGNC Official Full Name bone morphogenetic protein 4provided by HGNC Primary source HGNC:HGNC:1071 See related Ensembl:ENSG00000125378 MIM:112262; AllianceGenome:HGNC:1071 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016] Expression Broad expression in placenta (RPKM 12.6), urinary bladder (RPKM 7.5) and 20 other tissues See more Orthologs mouse all
BMP5, Official Symbol BMP5provided by HGNC Official Full Name bone morphogenetic protein 5provided by HGNC Primary source HGNC:HGNC:1072 See related Ensembl:ENSG00000112175 MIM:112265; AllianceGenome:HGNC:1072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] Expression Biased expression in placenta (RPKM 11.7), lung (RPKM 3.1) and 7 other tissues See more Orthologs mouse all
BMP6, Official Symbol BMP6provided by HGNC Official Full Name bone morphogenetic protein 6provided by HGNC Primary source HGNC:HGNC:1073 See related Ensembl:ENSG00000153162 MIM:112266; AllianceGenome:HGNC:1073 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IO; VGR; VGR1 Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in placenta (RPKM 15.8), lung (RPKM 11.0) and 24 other tissues See more Orthologs mouse all
BMP7, Official Symbol BMP7provided by HGNC Official Full Name bone morphogenetic protein 7provided by HGNC Primary source HGNC:HGNC:1074 See related Ensembl:ENSG00000101144 MIM:112267; AllianceGenome:HGNC:1074 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OP-1 Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016] Expression Biased expression in thyroid (RPKM 30.0), placenta (RPKM 15.8) and 9 other tissues See more Orthologs mouse all
BMP8A, Official Symbol BMP8Aprovided by HGNC Official Full Name bone morphogenetic protein 8aprovided by HGNC Primary source HGNC:HGNC:21650 See related Ensembl:ENSG00000183682 AllianceGenome:HGNC:21650 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Op2; OP-2 Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016] Expression Biased expression in thyroid (RPKM 57.4) and endometrium (RPKM 2.6) See more Orthologs mouse all
BMP8B, Official Symbol BMP8Bprovided by HGNC Official Full Name bone morphogenetic protein 8bprovided by HGNC Primary source HGNC:HGNC:1075 See related Ensembl:ENSG00000116985 MIM:602284; AllianceGenome:HGNC:1075 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OP2; BMP8 Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016] Expression Broad expression in thyroid (RPKM 7.4), adrenal (RPKM 2.8) and 20 other tissues See more Orthologs mouse all
BMP8B-AS1, Official Symbol BMP8B-AS1provided by HGNC Official Full Name BMP8B antisense RNA 1provided by HGNC Primary source HGNC:HGNC:54364 See related Ensembl:ENSG00000285905 AllianceGenome:HGNC:54364 Gene type ncRNA RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 2.6) See more
BMPER, Official Symbol BMPERprovided by HGNC Official Full Name BMP binding endothelial regulatorprovided by HGNC Primary source HGNC:HGNC:24154 See related Ensembl:ENSG00000164619 MIM:608699; AllianceGenome:HGNC:24154 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CV2; CV-2; CRIM3 Summary This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011] Expression Broad expression in prostate (RPKM 4.5), brain (RPKM 3.2) and 19 other tissues See more Orthologs mouse all
BMPR1A, Official Symbol BMPR1Aprovided by HGNC Official Full Name bone morphogenetic protein receptor type 1Aprovided by HGNC Primary source HGNC:HGNC:1076 See related Ensembl:ENSG00000107779 MIM:601299; AllianceGenome:HGNC:1076 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALK3; SKR5; ALK-3; CD292; ACVRLK3; BMPR-1A; 10q23del Summary The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 14.8), endometrium (RPKM 10.0) and 23 other tissues See more Orthologs mouse all
BMPR1AP1, Official Symbol BMPR1AP1provided by HGNC Official Full Name bone morphogenetic protein receptor type 1A pseudogene 1provided by HGNC Primary source HGNC:HGNC:21742 See related Ensembl:ENSG00000219642 AllianceGenome:HGNC:21742 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMPR1APS1
BMPR1B, Official Symbol BMPR1Bprovided by HGNC Official Full Name bone morphogenetic protein receptor type 1Bprovided by HGNC Primary source HGNC:HGNC:1077 See related Ensembl:ENSG00000138696 MIM:603248; AllianceGenome:HGNC:1077 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALK6; AMD3; AMDD; BDA2; ALK-6; BDA1D; CDw293 Summary This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] Expression Biased expression in prostate (RPKM 14.5), brain (RPKM 5.7) and 7 other tissues See more Orthologs mouse all
BMPR1B-DT, Official Symbol BMPR1B-DTprovided by HGNC Official Full Name BMPR1B divergent transcriptprovided by HGNC Primary source HGNC:HGNC:50864 See related Ensembl:ENSG00000249599 AllianceGenome:HGNC:50864 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMPR1B-AS1 Expression Biased expression in testis (RPKM 5.0), prostate (RPKM 3.8) and 3 other tissues See more
BMPR2, Official Symbol BMPR2provided by HGNC Official Full Name bone morphogenetic protein receptor type 2provided by HGNC Primary source HGNC:HGNC:1078 See related Ensembl:ENSG00000204217 MIM:600799; AllianceGenome:HGNC:1078 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II Summary This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020] Expression Ubiquitous expression in lung (RPKM 16.2), brain (RPKM 15.1) and 24 other tissues See more Orthologs mouse all
BMS1, Official Symbol BMS1provided by HGNC Official Full Name BMS1 ribosome biogenesis factorprovided by HGNC Primary source HGNC:HGNC:23505 See related Ensembl:ENSG00000165733 MIM:611448; AllianceGenome:HGNC:23505 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACC; BMS1L Summary This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.[provided by RefSeq, Mar 2009] Expression Ubiquitous expression in testis (RPKM 6.4), appendix (RPKM 5.6) and 25 other tissues See more Orthologs mouse all
BMS1P1, Official Symbol BMS1P1provided by HGNC Official Full Name BMS1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:23649 See related Ensembl:ENSG00000291069 AllianceGenome:HGNC:23649 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMS1P5; BMS1LP1; BMS1LP5 Expression Ubiquitous expression in duodenum (RPKM 4.6), small intestine (RPKM 3.8) and 25 other tissues See more
BMS1P10, Official Symbol BMS1P10provided by HGNC Official Full Name BMS1 pseudogene 10provided by HGNC Primary source HGNC:HGNC:49154 See related Ensembl:ENSG00000237238 AllianceGenome:HGNC:49154 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMS1P11, Official Symbol BMS1P11provided by HGNC Official Full Name BMS1 pseudogene 11provided by HGNC Primary source HGNC:HGNC:49156 See related Ensembl:ENSG00000225883 AllianceGenome:HGNC:49156 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMS1P12, Official Symbol BMS1P12provided by HGNC Official Full Name BMS1 pseudogene 12provided by HGNC Primary source HGNC:HGNC:49157 See related AllianceGenome:HGNC:49157 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMS1P13, Official Symbol BMS1P13provided by HGNC Official Full Name BMS1 pseudogene 13provided by HGNC Primary source HGNC:HGNC:49158 See related Ensembl:ENSG00000231701 AllianceGenome:HGNC:49158 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMS1P14
BMS1P15, Official Symbol BMS1P15provided by HGNC Official Full Name BMS1 pseudogene 15provided by HGNC Primary source HGNC:HGNC:49160 See related Ensembl:ENSG00000258780 AllianceGenome:HGNC:49160 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMS1P16, Official Symbol BMS1P16provided by HGNC Official Full Name BMS1 pseudogene 16provided by HGNC Primary source HGNC:HGNC:49161 See related Ensembl:ENSG00000258684 AllianceGenome:HGNC:49161 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMS1P23, Official Symbol BMS1P23provided by HGNC Official Full Name BMS1 pseudogene 23provided by HGNC Primary source HGNC:HGNC:55088 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information Note: GeneID:728034 originally represented the BMS1P14 pseudogene, but was misplaced for build 38.1. This GeneID now represents a different pseudogene of BMS1 with a distinct sequence from BMS1P14. BMS1P14 was determined to be redundant with BMS1P13 (GeneID:644716). [09 Mar 2017]
BMS1P3, Official Symbol BMS1P3provided by HGNC Official Full Name BMS1 pseudogene 3provided by HGNC Primary source HGNC:HGNC:23651 See related Ensembl:ENSG00000240089 AllianceGenome:HGNC:23651 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMS1LP3
BMS1P4-AGAP5, Official Symbol BMS1P4-AGAP5provided by HGNC Official Full Name BMS1P4-AGAP5 readthroughprovided by HGNC Primary source HGNC:HGNC:55636 See related Ensembl:ENSG00000242288 AllianceGenome:HGNC:55636 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring readthrough transcription between the neighboring BMS1P4 (BMS1, ribosome biogenesis factor pseudogene 4) and AGAP5 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 5) genes on chromosome 10. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Jan 2019]
BMS1P9, Official Symbol BMS1P9provided by HGNC Official Full Name BMS1 pseudogene 9provided by HGNC Primary source HGNC:HGNC:49155 See related Ensembl:ENSG00000198312 AllianceGenome:HGNC:49155 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BMT2, Official Symbol BMT2provided by HGNC Official Full Name base methyltransferase of 25S rRNA 2 homologprovided by HGNC Primary source HGNC:HGNC:26475 See related Ensembl:ENSG00000164603 MIM:617855; AllianceGenome:HGNC:26475 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAMTOR; C7orf60 Summary Enables S-adenosyl-L-methionine binding activity. Involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Colocalizes with GATOR1 complex and KICSTOR complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.8), heart (RPKM 5.2) and 25 other tissues See more Orthologs mouse all
BMX, Official Symbol BMXprovided by HGNC Official Full Name BMX non-receptor tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:1079 See related Ensembl:ENSG00000102010 MIM:300101; AllianceGenome:HGNC:1079 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ETK; PSCTK2; PSCTK3 Summary This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Expression Broad expression in bone marrow (RPKM 2.4), placenta (RPKM 2.2) and 21 other tissues See more Orthologs mouse all
BNC1, Official Symbol BNC1provided by HGNC Official Full Name basonuclin zinc finger protein 1provided by HGNC Primary source HGNC:HGNC:1081 See related Ensembl:ENSG00000169594 MIM:601930; AllianceGenome:HGNC:1081 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BNC; bn1; BSN1; POF16; HsT19447 Summary This gene encodes a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. Disruption of this gene has been implicated in premature ovarian failure as well as testicular premature aging. [provided by RefSeq, Sep 2020] Expression Biased expression in testis (RPKM 16.5), esophagus (RPKM 5.8) and 2 other tissues See more Orthologs mouse all
BNC2, Official Symbol BNC2provided by HGNC Official Full Name basonuclin zinc finger protein 2provided by HGNC Primary source HGNC:HGNC:30988 See related Ensembl:ENSG00000173068 MIM:608669; AllianceGenome:HGNC:30988 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as bn2; BSN2; LUTO Summary This gene encodes a conserved zinc finger protein. The encoded protein functions in skin color saturation. Mutations in this gene are associated with facial pigmented spots. This gene is also associated with susceptibility to adolescent idiopathic scoliosis. [provided by RefSeq, Jul 2016] Expression Biased expression in endometrium (RPKM 6.6), ovary (RPKM 5.5) and 13 other tissues See more Orthologs mouse all
BNC2-AS1, Official Symbol BNC2-AS1provided by HGNC Official Full Name BNC2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53727 See related Ensembl:ENSG00000234779 AllianceGenome:HGNC:53727 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP1, Official Symbol BNIP1provided by HGNC Official Full Name BCL2 interacting protein 1provided by HGNC Primary source HGNC:HGNC:1082 See related Ensembl:ENSG00000113734 MIM:603291; AllianceGenome:HGNC:1082 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIP1; SEC20; TRG-8 Summary This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011] Expression Ubiquitous expression in bone marrow (RPKM 8.6), testis (RPKM 6.9) and 25 other tissues See more Orthologs mouse all
BNIP2, Official Symbol BNIP2provided by HGNC Official Full Name BCL2 interacting protein 2provided by HGNC Primary source HGNC:HGNC:1083 See related Ensembl:ENSG00000140299 MIM:603292; AllianceGenome:HGNC:1083 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIP2; BNIP-2 Summary This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in bone marrow (RPKM 22.4), fat (RPKM 13.5) and 24 other tissues See more Orthologs mouse all
BNIP3, Official Symbol BNIP3provided by HGNC Official Full Name BCL2 interacting protein 3provided by HGNC Primary source HGNC:HGNC:1084 See related Ensembl:ENSG00000176171 MIM:603293; AllianceGenome:HGNC:1084 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIP3; HABON Summary This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in liver (RPKM 54.5), fat (RPKM 52.6) and 24 other tissues See more Orthologs mouse all
BNIP3L, Official Symbol BNIP3Lprovided by HGNC Official Full Name BCL2 interacting protein 3 likeprovided by HGNC Primary source HGNC:HGNC:1085 See related Ensembl:ENSG00000104765 MIM:605368; AllianceGenome:HGNC:1085 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIX; NIP3L; BNIP3a Summary This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015] Expression Ubiquitous expression in fat (RPKM 69.4), ovary (RPKM 49.9) and 24 other tissues See more Orthologs mouse all
BNIP3P1, Official Symbol BNIP3P1provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 1provided by HGNC Primary source HGNC:HGNC:19922 See related Ensembl:ENSG00000197358 AllianceGenome:HGNC:19922 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BNIP3P
BNIP3P10, Official Symbol BNIP3P10provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 10provided by HGNC Primary source HGNC:HGNC:49690 See related Ensembl:ENSG00000270270 AllianceGenome:HGNC:49690 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P11, Official Symbol BNIP3P11provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 11provided by HGNC Primary source HGNC:HGNC:49724 See related Ensembl:ENSG00000271550 AllianceGenome:HGNC:49724 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P15, Official Symbol BNIP3P15provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 15provided by HGNC Primary source HGNC:HGNC:49695 See related Ensembl:ENSG00000270716 AllianceGenome:HGNC:49695 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P16, Official Symbol BNIP3P16provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 16provided by HGNC Primary source HGNC:HGNC:49696 See related Ensembl:ENSG00000267641 AllianceGenome:HGNC:49696 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P17, Official Symbol BNIP3P17provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 17provided by HGNC Primary source HGNC:HGNC:49697 See related Ensembl:ENSG00000271524 AllianceGenome:HGNC:49697 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P18, Official Symbol BNIP3P18provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 18provided by HGNC Primary source HGNC:HGNC:49698 See related Ensembl:ENSG00000269055 AllianceGenome:HGNC:49698 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P19, Official Symbol BNIP3P19provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 19provided by HGNC Primary source HGNC:HGNC:49699 See related Ensembl:ENSG00000271638 AllianceGenome:HGNC:49699 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P2, Official Symbol BNIP3P2provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 2provided by HGNC Primary source HGNC:HGNC:39655 See related Ensembl:ENSG00000236097 AllianceGenome:HGNC:39655 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P20, Official Symbol BNIP3P20provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 20provided by HGNC Primary source HGNC:HGNC:49700 See related Ensembl:ENSG00000271704 AllianceGenome:HGNC:49700 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P22, Official Symbol BNIP3P22provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 22provided by HGNC Primary source HGNC:HGNC:49702 See related Ensembl:ENSG00000268174 AllianceGenome:HGNC:49702 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P23, Official Symbol BNIP3P23provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 23provided by HGNC Primary source HGNC:HGNC:49703 See related Ensembl:ENSG00000268335 AllianceGenome:HGNC:49703 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P25, Official Symbol BNIP3P25provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 25provided by HGNC Primary source HGNC:HGNC:49705 See related Ensembl:ENSG00000268322 AllianceGenome:HGNC:49705 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P26, Official Symbol BNIP3P26provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 26provided by HGNC Primary source HGNC:HGNC:49706 See related Ensembl:ENSG00000268705 AllianceGenome:HGNC:49706 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P28, Official Symbol BNIP3P28provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 28provided by HGNC Primary source HGNC:HGNC:49708 See related Ensembl:ENSG00000271095 AllianceGenome:HGNC:49708 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P29, Official Symbol BNIP3P29provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 29provided by HGNC Primary source HGNC:HGNC:49709 See related Ensembl:ENSG00000269742 AllianceGenome:HGNC:49709 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P3, Official Symbol BNIP3P3provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 3provided by HGNC Primary source HGNC:HGNC:39656 See related Ensembl:ENSG00000265631 AllianceGenome:HGNC:39656 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P32, Official Symbol BNIP3P32provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 32provided by HGNC Primary source HGNC:HGNC:49712 See related Ensembl:ENSG00000268830 AllianceGenome:HGNC:49712 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P33, Official Symbol BNIP3P33provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 33provided by HGNC Primary source HGNC:HGNC:49713 See related Ensembl:ENSG00000268717 AllianceGenome:HGNC:49713 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P34, Official Symbol BNIP3P34provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 34provided by HGNC Primary source HGNC:HGNC:49714 See related Ensembl:ENSG00000269509 AllianceGenome:HGNC:49714 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P35, Official Symbol BNIP3P35provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 35provided by HGNC Primary source HGNC:HGNC:49715 See related Ensembl:ENSG00000271655 AllianceGenome:HGNC:49715 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P36, Official Symbol BNIP3P36provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 36provided by HGNC Primary source HGNC:HGNC:49716 See related Ensembl:ENSG00000271661 AllianceGenome:HGNC:49716 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P37, Official Symbol BNIP3P37provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 37provided by HGNC Primary source HGNC:HGNC:49717 See related Ensembl:ENSG00000270479 AllianceGenome:HGNC:49717 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P38, Official Symbol BNIP3P38provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 38provided by HGNC Primary source HGNC:HGNC:49718 See related Ensembl:ENSG00000268469 AllianceGenome:HGNC:49718 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P39, Official Symbol BNIP3P39provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 39provided by HGNC Primary source HGNC:HGNC:49719 See related Ensembl:ENSG00000269662 AllianceGenome:HGNC:49719 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P4, Official Symbol BNIP3P4provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 4provided by HGNC Primary source HGNC:HGNC:39657 See related Ensembl:ENSG00000271225 AllianceGenome:HGNC:39657 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P40, Official Symbol BNIP3P40provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 40provided by HGNC Primary source HGNC:HGNC:49720 See related Ensembl:ENSG00000268058 AllianceGenome:HGNC:49720 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P42, Official Symbol BNIP3P42provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 42provided by HGNC Primary source HGNC:HGNC:49722 See related Ensembl:ENSG00000223974 AllianceGenome:HGNC:49722 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P5, Official Symbol BNIP3P5provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 5provided by HGNC Primary source HGNC:HGNC:39658 See related AllianceGenome:HGNC:39658 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P6, Official Symbol BNIP3P6provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 6provided by HGNC Primary source HGNC:HGNC:39659 See related Ensembl:ENSG00000257356 AllianceGenome:HGNC:39659 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P8, Official Symbol BNIP3P8provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 8provided by HGNC Primary source HGNC:HGNC:49675 See related Ensembl:ENSG00000269431 AllianceGenome:HGNC:49675 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP3P9, Official Symbol BNIP3P9provided by HGNC Official Full Name BCL2 interacting protein 3 pseudogene 9provided by HGNC Primary source HGNC:HGNC:49689 See related Ensembl:ENSG00000270325 AllianceGenome:HGNC:49689 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
BNIP5, Official Symbol BNIP5provided by HGNC Official Full Name BCL2 interacting protein 5provided by HGNC Primary source HGNC:HGNC:33769 See related Ensembl:ENSG00000189325 AllianceGenome:HGNC:33769 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf222 Expression Biased expression in small intestine (RPKM 9.9), duodenum (RPKM 9.6) and 3 other tissues See more Orthologs mouse all
BNIPL, Official Symbol BNIPLprovided by HGNC Official Full Name BCL2 interacting protein likeprovided by HGNC Primary source HGNC:HGNC:16976 See related Ensembl:ENSG00000163141 MIM:611275; AllianceGenome:HGNC:16976 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BNIPS; PP753; BNIP-S; BNIPL1; BNIPL2; BNIPL-1; BNIPL-2; BNIP-Sbeta; BNIP-Salpha Summary The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Expression Biased expression in skin (RPKM 64.5), esophagus (RPKM 30.1) and 1 other tissue See more Orthologs mouse all
BOC, Official Symbol BOCprovided by HGNC Official Full Name BOC cell adhesion associated, oncogene regulatedprovided by HGNC Primary source HGNC:HGNC:17173 See related Ensembl:ENSG00000144857 MIM:608708; AllianceGenome:HGNC:17173 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Boi; CDON2 Summary The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014] Expression Broad expression in skin (RPKM 11.2), prostate (RPKM 10.0) and 23 other tissues See more Orthologs mouse all
BOD1, Official Symbol BOD1provided by HGNC Official Full Name biorientation of chromosomes in cell division 1provided by HGNC Primary source HGNC:HGNC:25114 See related Ensembl:ENSG00000145919 MIM:616745; AllianceGenome:HGNC:25114 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM44B Summary Enables protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Involved in mitotic sister chromatid segregation; negative regulation of phosphoprotein phosphatase activity; and protein localization to chromosome, centromeric region. Located in centrosome; spindle microtubule; and spindle pole. Part of outer kinetochore. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 15.5), ovary (RPKM 14.9) and 25 other tissues See more Orthologs mouse all