psui3905/ncbi_genes_summary huggingface dataset:
TRAV7, Official Symbol TRAV7provided by HGNC Official Full Name T cell receptor alpha variable 7provided by HGNC Primary source HGNC:HGNC:12145 See related Ensembl:ENSG00000211781 IMGT/GENE-DB:TRAV7; AllianceGenome:HGNC:12145 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRAV7S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV8-1, Official Symbol TRAV8-1provided by HGNC Official Full Name T cell receptor alpha variable 8-1provided by HGNC Primary source HGNC:HGNC:12146 See related Ensembl:ENSG00000211782 IMGT/GENE-DB:TRAV8-1; AllianceGenome:HGNC:12146 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV81; TCRAV1S1; TCRAV8S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV8-2, Official Symbol TRAV8-2provided by HGNC Official Full Name T cell receptor alpha variable 8-2provided by HGNC Primary source HGNC:HGNC:12147 See related Ensembl:ENSG00000211786 IMGT/GENE-DB:TRAV8-2; AllianceGenome:HGNC:12147 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV82; TCRAV1S5; TCRAV8S2 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV8-3, Official Symbol TRAV8-3provided by HGNC Official Full Name T cell receptor alpha variable 8-3provided by HGNC Primary source HGNC:HGNC:12148 See related Ensembl:ENSG00000211787 IMGT/GENE-DB:TRAV8-3; AllianceGenome:HGNC:12148 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV83; TCRAV1S4; TCRAV8S3 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV8-4, Official Symbol TRAV8-4provided by HGNC Official Full Name T cell receptor alpha variable 8-4provided by HGNC Primary source HGNC:HGNC:12149 See related Ensembl:ENSG00000211790 IMGT/GENE-DB:TRAV8-4; AllianceGenome:HGNC:12149 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV84; TCRAV1S2; TCRAV8S4 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV8-6, Official Symbol TRAV8-6provided by HGNC Official Full Name T cell receptor alpha variable 8-6provided by HGNC Primary source HGNC:HGNC:12151 See related Ensembl:ENSG00000211795 IMGT/GENE-DB:TRAV8-6; AllianceGenome:HGNC:12151 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV86; TCRAV1S3; TCRAV8S6 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV9-1, Official Symbol TRAV9-1provided by HGNC Official Full Name T cell receptor alpha variable 9-1provided by HGNC Primary source HGNC:HGNC:12153 See related Ensembl:ENSG00000211783 IMGT/GENE-DB:TRAV9-1; AllianceGenome:HGNC:12153 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV91; TCRAV9S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRAV9-2, Official Symbol TRAV9-2provided by HGNC Official Full Name T cell receptor alpha variable 9-2provided by HGNC Primary source HGNC:HGNC:12154 See related Ensembl:ENSG00000211793 IMGT/GENE-DB:TRAV9-2; AllianceGenome:HGNC:12154 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRAV92; TCRAV9S2; TCRAV22S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRBJ1-6, Official Symbol TRBJ1-6provided by HGNC Official Full Name T cell receptor beta joining 1-6provided by HGNC Primary source HGNC:HGNC:12167 See related Ensembl:ENSG00000282780 IMGT/GENE-DB:TRBJ1-6; AllianceGenome:HGNC:12167 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBJ16; TCRBJ1S6 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBJ2-4, Official Symbol TRBJ2-4provided by HGNC Official Full Name T cell receptor beta joining 2-4provided by HGNC Primary source HGNC:HGNC:12172 See related Ensembl:ENSG00000211768 IMGT/GENE-DB:TRBJ2-4; AllianceGenome:HGNC:12172 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBJ24; TCRBJ2S4 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBJ2-5, Official Symbol TRBJ2-5provided by HGNC Official Full Name T cell receptor beta joining 2-5provided by HGNC Primary source HGNC:HGNC:12173 See related Ensembl:ENSG00000211769 IMGT/GENE-DB:TRBJ2-5; AllianceGenome:HGNC:12173 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBJ25; TCRBJ2S5 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBJ2-6, Official Symbol TRBJ2-6provided by HGNC Official Full Name T cell receptor beta joining 2-6provided by HGNC Primary source HGNC:HGNC:12174 See related Ensembl:ENSG00000211770 IMGT/GENE-DB:TRBJ2-6; AllianceGenome:HGNC:12174 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBJ26; TCRBJ2S6 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBJ2-7, Official Symbol TRBJ2-7provided by HGNC Official Full Name T cell receptor beta joining 2-7provided by HGNC Primary source HGNC:HGNC:12175 See related Ensembl:ENSG00000211771 IMGT/GENE-DB:TRBJ2-7; AllianceGenome:HGNC:12175 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBJ27; TCRBJ2S7 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV1, Official Symbol TRBV1provided by HGNC Official Full Name T cell receptor beta variable 1 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12176 See related IMGT/GENE-DB:TRBV1; AllianceGenome:HGNC:12176 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV1S1P; TCRBV27S1P Annotation information Annotation category: partial on reference assembly
TRBV12-3, Official Symbol TRBV12-3provided by HGNC Official Full Name T cell receptor beta variable 12-3provided by HGNC Primary source HGNC:HGNC:12185 See related Ensembl:ENSG00000274752 IMGT/GENE-DB:TRBV12-3; AllianceGenome:HGNC:12185 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV123; TCRBV8S1; TCRBV12S3 Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV12-5, Official Symbol TRBV12-5provided by HGNC Official Full Name T cell receptor beta variable 12-5provided by HGNC Primary source HGNC:HGNC:12187 See related Ensembl:ENSG00000275158 IMGT/GENE-DB:TRBV12-5; AllianceGenome:HGNC:12187 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV125; TCRBV8S3; TCRBV12S5 Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV16, Official Symbol TRBV16provided by HGNC Official Full Name T cell receptor beta variable 16provided by HGNC Primary source HGNC:HGNC:12191 See related Ensembl:ENSG00000275243 IMGT/GENE-DB:TRBV16; AllianceGenome:HGNC:12191 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRB; TCRBV16S1; TCRBV25S1; BV25S1J1.2; TCRBV25S1A2PT Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
TRBV18, Official Symbol TRBV18provided by HGNC Official Full Name T cell receptor beta variable 18provided by HGNC Primary source HGNC:HGNC:12193 See related Ensembl:ENSG00000276557 IMGT/GENE-DB:TRBV18; AllianceGenome:HGNC:12193 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV18S1 Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV20OR9-2, Official Symbol TRBV20OR9-2provided by HGNC Official Full Name T cell receptor beta variable 20/OR9-2 (non-functional)provided by HGNC Primary source HGNC:HGNC:12197 See related Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
TRBV21OR9-2, Official Symbol TRBV21OR9-2provided by HGNC Official Full Name T cell receptor beta variable 21/OR9-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12199 See related Ensembl:ENSG00000183938 IMGT/GENE-DB:TRBV21/OR9-2; AllianceGenome:HGNC:12199 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV10O; TCRBV21S2; TCRBV10S2O
TRBV23OR9-2, Official Symbol TRBV23OR9-2provided by HGNC Official Full Name T cell receptor beta variable 23/OR9-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12202 See related Ensembl:ENSG00000229063 IMGT/GENE-DB:TRBV23/OR9-2; AllianceGenome:HGNC:12202 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV23S2; TCRBV19S2O; TRBV23OR92
TRBV24OR9-2, Official Symbol TRBV24OR9-2provided by HGNC Official Full Name T cell receptor beta variable 24/OR9-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12204 See related Ensembl:ENSG00000215206 IMGT/GENE-DB:TRBV24/OR9-2; AllianceGenome:HGNC:12204 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV15O; TCRBV24S2; TCRBV15S2O
TRBV25OR9-2, Official Symbol TRBV25OR9-2provided by HGNC Official Full Name T cell receptor beta variable 25/OR9-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12206 See related Ensembl:ENSG00000240215 IMGT/GENE-DB:TRBV25/OR9-2; AllianceGenome:HGNC:12206 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV11O; TCRBV25S2; TCRBV11S2O
TRBV26OR9-2, Official Symbol TRBV26OR9-2provided by HGNC Official Full Name T cell receptor beta variable 26/OR9-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:15485 See related Ensembl:ENSG00000231165 IMGT/GENE-DB:TRBV26/OR9-2; AllianceGenome:HGNC:15485 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV26S2; TCRBV28S2; TCRBV28S2O
TRBV29OR9-2, Official Symbol TRBV29OR9-2provided by HGNC Official Full Name T cell receptor beta variable 29/OR9-2 (non-functional)provided by HGNC Primary source HGNC:HGNC:12211 See related Ensembl:ENSG00000223394 IMGT/GENE-DB:TRBV29/OR9-2; AllianceGenome:HGNC:12211 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV4O; TCRBV29S2; TCRBV4S2O; TRBV29/OR9-2
TRBV30, Official Symbol TRBV30provided by HGNC Official Full Name T cell receptor beta variable 30provided by HGNC Primary source HGNC:HGNC:12214 See related Ensembl:ENSG00000237254 IMGT/GENE-DB:TRBV30; AllianceGenome:HGNC:12214 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV30S1; TCRBV20S1A1N2 Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV4-1, Official Symbol TRBV4-1provided by HGNC Official Full Name T cell receptor beta variable 4-1provided by HGNC Primary source HGNC:HGNC:12215 See related Ensembl:ENSG00000211710 IMGT/GENE-DB:TRBV4-1; AllianceGenome:HGNC:12215 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV41; TCRBV4S1; BV07S1J2.7; TCRBV7S1A1N2T Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV4-2, Official Symbol TRBV4-2provided by HGNC Official Full Name T cell receptor beta variable 4-2provided by HGNC Primary source HGNC:HGNC:12216 See related Ensembl:ENSG00000211745 IMGT/GENE-DB:TRBV4-2; AllianceGenome:HGNC:12216 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV42; TCRBV4S2; TCRBV7S3A2; TCRBV7S3A2T Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV5-3, Official Symbol TRBV5-3provided by HGNC Official Full Name T cell receptor beta variable 5-3 (non-functional)provided by HGNC Primary source HGNC:HGNC:12220 See related Ensembl:ENSG00000211715 IMGT/GENE-DB:TRBV5-3; AllianceGenome:HGNC:12220 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV53; TCRBV5S3; TCRBV5S5P Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV5-4, Official Symbol TRBV5-4provided by HGNC Official Full Name T cell receptor beta variable 5-4provided by HGNC Primary source HGNC:HGNC:12221 See related Ensembl:ENSG00000230099 IMGT/GENE-DB:TRBV5-4; AllianceGenome:HGNC:12221 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV54; TCRBV5S4; TCRBV5S6A3N2T Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV6-2, Official Symbol TRBV6-2provided by HGNC Official Full Name T cell receptor beta variable 6-2provided by HGNC Primary source HGNC:HGNC:12227 See related IMGT/GENE-DB:TRBV6-2; AllianceGenome:HGNC:12227 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV62; TCRBV6S2; TCRBV13S2; TCRBV13S2A1T Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: only annotated on alternate loci in reference assembly
TRBV7-5, Official Symbol TRBV7-5provided by HGNC Official Full Name T cell receptor beta variable 7-5 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12239 See related Ensembl:ENSG00000227550 IMGT/GENE-DB:TRBV7-5; AllianceGenome:HGNC:12239 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV75; TCRBV7S5; TCRBV6S9P Annotation information Annotation category: partial on reference assembly
TRBV7-9, Official Symbol TRBV7-9provided by HGNC Official Full Name T cell receptor beta variable 7-9provided by HGNC Primary source HGNC:HGNC:12243 See related Ensembl:ENSG00000278030 IMGT/GENE-DB:TRBV7-9; AllianceGenome:HGNC:12243 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRB; TRBV79; TCRBV7S9; TCRBV6S4A1 Summary Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRBV8-2, Official Symbol TRBV8-2provided by HGNC Official Full Name T cell receptor beta variable 8-2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12245 See related IMGT/GENE-DB:TRBV8-2; AllianceGenome:HGNC:12245 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRBV82; TCRBV32S1P Annotation information Annotation category: partial on reference assembly
TRBVA, Official Symbol TRBVAprovided by HGNC Official Full Name T cell receptor beta variable A (pseudogene)provided by HGNC Primary source HGNC:HGNC:12247 See related Ensembl:ENSG00000239992 IMGT/GENE-DB:TRBVA; AllianceGenome:HGNC:12247 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV33S1
TRBVB, Official Symbol TRBVBprovided by HGNC Official Full Name T cell receptor beta variable B (pseudogene)provided by HGNC Primary source HGNC:HGNC:12248 See related Ensembl:ENSG00000241911 IMGT/GENE-DB:TRBVB; AllianceGenome:HGNC:12248 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRBV34S1
TRDC, Official Symbol TRDCprovided by HGNC Official Full Name T cell receptor delta constantprovided by HGNC Primary source HGNC:HGNC:12253 See related IMGT/GENE-DB:TRDC; MIM:186810; AllianceGenome:HGNC:12253 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRD Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDD1, Official Symbol TRDD1provided by HGNC Official Full Name T cell receptor delta diversity 1provided by HGNC Primary source HGNC:HGNC:12254 See related Ensembl:ENSG00000223997 IMGT/GENE-DB:TRDD1; AllianceGenome:HGNC:12254 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDD2, Official Symbol TRDD2provided by HGNC Official Full Name T cell receptor delta diversity 2provided by HGNC Primary source HGNC:HGNC:12255 See related Ensembl:ENSG00000237235 IMGT/GENE-DB:TRDD2; AllianceGenome:HGNC:12255 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDD3, Official Symbol TRDD3provided by HGNC Official Full Name T cell receptor delta diversity 3provided by HGNC Primary source HGNC:HGNC:12256 See related Ensembl:ENSG00000228985 IMGT/GENE-DB:TRDD3; AllianceGenome:HGNC:12256 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRD Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly