psui3905/ncbi_genes_summary huggingface dataset:
TTLL1, Official Symbol TTLL1provided by HGNC Official Full Name TTL family tubulin polyglutamylase complex subunit L1provided by HGNC Primary source HGNC:HGNC:1312 See related Ensembl:ENSG00000100271 MIM:608955; AllianceGenome:HGNC:1312 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TPGS3; C22orf7; HS323M22B Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within several processes, including cerebellar Purkinje cell differentiation; mucociliary clearance; and regulation of blastocyst development. Predicted to be located in cytoplasm; extracellular region; and microtubule cytoskeleton. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 7.3), brain (RPKM 5.8) and 24 other tissues See more Orthologs mouse all
TTLL1-AS1, Official Symbol TTLL1-AS1provided by HGNC Official Full Name TTLL1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40111 See related Ensembl:ENSG00000230319 AllianceGenome:HGNC:40111 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 1.2), brain (RPKM 1.1) and 22 other tissues See more
TTLL10, Official Symbol TTLL10provided by HGNC Official Full Name tubulin tyrosine ligase like 10provided by HGNC Primary source HGNC:HGNC:26693 See related Ensembl:ENSG00000162571 AllianceGenome:HGNC:26693 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTLL5 Summary Predicted to enable protein-glycine ligase activity, elongating. Predicted to be involved in protein polyglycylation. Predicted to be located in axoneme and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 6.9), lung (RPKM 0.7) and 1 other tissue See more Orthologs mouse all
TTLL10-AS1, Official Symbol TTLL10-AS1provided by HGNC Official Full Name TTLL10 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41159 See related Ensembl:ENSG00000205231 AllianceGenome:HGNC:41159 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in testis (RPKM 1.2), lung (RPKM 0.5) and 3 other tissues See more
TTLL11, Official Symbol TTLL11provided by HGNC Official Full Name tubulin tyrosine ligase like 11provided by HGNC Primary source HGNC:HGNC:18113 See related Ensembl:ENSG00000175764 AllianceGenome:HGNC:18113 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C9orf20; C9orf148; TTLL11-IT1; bA244O19.1 Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within microtubule severing. Predicted to be located in cytosol. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 2.0), testis (RPKM 1.0) and 25 other tissues See more Orthologs mouse all
TTLL12, Official Symbol TTLL12provided by HGNC Official Full Name tubulin tyrosine ligase like 12provided by HGNC Primary source HGNC:HGNC:28974 See related Ensembl:ENSG00000100304 MIM:619410; AllianceGenome:HGNC:28974 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ526I14.2 Summary Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 28.7), colon (RPKM 16.0) and 25 other tissues See more Orthologs mouse all
TTLL2, Official Symbol TTLL2provided by HGNC Official Full Name tubulin tyrosine ligase like 2provided by HGNC Primary source HGNC:HGNC:21211 See related Ensembl:ENSG00000120440 AllianceGenome:HGNC:21211 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf104; NYD-TSPG; dJ366N23.3 Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 9.5) See more Orthologs mouse all
TTLL3, Official Symbol TTLL3provided by HGNC Official Full Name tubulin tyrosine ligase like 3provided by HGNC Primary source HGNC:HGNC:24483 See related Ensembl:ENSG00000214021 MIM:619195; AllianceGenome:HGNC:24483 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOTTL Summary Enables protein-glycine ligase activity. Predicted to be involved in axoneme assembly and flagellated sperm motility. Predicted to be located in axoneme; microtubule cytoskeleton; and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 13.9), testis (RPKM 13.9) and 24 other tissues See more Orthologs mouse all
TTLL4, Official Symbol TTLL4provided by HGNC Official Full Name tubulin tyrosine ligase like 4provided by HGNC Primary source HGNC:HGNC:28976 See related Ensembl:ENSG00000135912 MIM:618738; AllianceGenome:HGNC:28976 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within regulation of blastocyst development. Predicted to be located in cytosol. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 10.4), brain (RPKM 3.1) and 24 other tissues See more Orthologs mouse all
TTLL5, Official Symbol TTLL5provided by HGNC Official Full Name tubulin tyrosine ligase like 5provided by HGNC Primary source HGNC:HGNC:19963 See related Ensembl:ENSG00000119685 MIM:612268; AllianceGenome:HGNC:19963 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STAMP; CORD19; KIAA0998 Summary This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.[provided by RefSeq, Feb 2010] Expression Broad expression in testis (RPKM 39.2), thyroid (RPKM 5.0) and 22 other tissues See more Orthologs mouse all
TTLL6, Official Symbol TTLL6provided by HGNC Official Full Name tubulin tyrosine ligase like 6provided by HGNC Primary source HGNC:HGNC:26664 See related Ensembl:ENSG00000170703 MIM:610849; AllianceGenome:HGNC:26664 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTL.6 Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within microtubule bundle formation; microtubule severing; and positive regulation of cilium movement. Located in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 10.4), colon (RPKM 1.9) and 5 other tissues See more Orthologs mouse all
TTLL7, Official Symbol TTLL7provided by HGNC Official Full Name tubulin tyrosine ligase like 7provided by HGNC Primary source HGNC:HGNC:26242 See related Ensembl:ENSG00000137941 MIM:618813; AllianceGenome:HGNC:26242 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables alpha-tubulin binding activity; beta-tubulin binding activity; and tubulin-glutamic acid ligase activity. Involved in protein polyglutamylation. Predicted to be located in 9+0 non-motile cilium and ciliary basal body. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 22.0), prostate (RPKM 4.2) and 14 other tissues See more Orthologs mouse all
TTLL7-IT1, Official Symbol TTLL7-IT1provided by HGNC Official Full Name TTLL7 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41486 See related Ensembl:ENSG00000233061 AllianceGenome:HGNC:41486 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TTLL8, Official Symbol TTLL8provided by HGNC Official Full Name tubulin tyrosine ligase like 8provided by HGNC Primary source HGNC:HGNC:34000 See related Ensembl:ENSG00000138892 MIM:619193; AllianceGenome:HGNC:34000 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable protein-glycine ligase activity, initiating. Predicted to be involved in protein polyglycylation. Predicted to act upstream of or within cilium assembly. Predicted to be located in axoneme and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward testis (RPKM 2.3) See more Orthologs mouse all
TTLL9, Official Symbol TTLL9provided by HGNC Official Full Name tubulin tyrosine ligase like 9provided by HGNC Primary source HGNC:HGNC:16118 See related Ensembl:ENSG00000131044 MIM:619838; AllianceGenome:HGNC:16118 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf125 Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within flagellated sperm motility. Predicted to be located in ciliary basal body; cytoplasm; and microtubule. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 3.4), brain (RPKM 0.8) and 3 other tissues See more Orthologs mouse all
TTN, Official Symbol TTNprovided by HGNC Official Full Name titinprovided by HGNC Primary source HGNC:HGNC:12403 See related Ensembl:ENSG00000155657 MIM:188840; AllianceGenome:HGNC:12403 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TMD; CMH9; CMD1G; CMPD4; CMYP5; EOMFC; HMERF; MYLK5; SALMY; LGMD2J; LGMDR10 Summary This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma. [provided by RefSeq, Feb 2012] Expression Biased expression in heart (RPKM 14.7), prostate (RPKM 1.9) and 1 other tissue See more Orthologs mouse all
TTN-AS1, Official Symbol TTN-AS1provided by HGNC Official Full Name TTN antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44124 See related Ensembl:ENSG00000237298 AllianceGenome:HGNC:44124 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a non-coding RNA transcribed from the opposite strand to the titin gene. [provided by RefSeq, Aug 2016] Expression Broad expression in heart (RPKM 12.7), bone marrow (RPKM 4.6) and 14 other tissues See more
TTPA, Official Symbol TTPAprovided by HGNC Official Full Name alpha tocopherol transfer proteinprovided by HGNC Primary source HGNC:HGNC:12404 See related Ensembl:ENSG00000137561 MIM:600415; AllianceGenome:HGNC:12404 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATTP; AVED; TTP1; alphaTTP Summary This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009] Expression Biased expression in liver (RPKM 30.1) and colon (RPKM 1.4) See more Orthologs mouse all
TTPAL, Official Symbol TTPALprovided by HGNC Official Full Name alpha tocopherol transfer protein likeprovided by HGNC Primary source HGNC:HGNC:16114 See related Ensembl:ENSG00000124120 AllianceGenome:HGNC:16114 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf121 Summary Predicted to enable phosphatidylinositol bisphosphate binding activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 4.7), thyroid (RPKM 4.2) and 25 other tissues See more Orthologs mouse all
TTR, Official Symbol TTRprovided by HGNC Official Full Name transthyretinprovided by HGNC Primary source HGNC:HGNC:12405 See related Ensembl:ENSG00000118271 MIM:176300; AllianceGenome:HGNC:12405 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTS; TTN; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651 Summary This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017] Expression Restricted expression toward liver (RPKM 2070.5) See more Orthologs mouse all
TTTY1, Official Symbol TTTY1provided by HGNC Official Full Name testis expressed transcript, Y-linked 1provided by HGNC Primary source HGNC:HGNC:14022 See related Ensembl:ENSG00000129845 AllianceGenome:HGNC:14022 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY1; LINC00033; NCRNA00033 Expression Low expression observed in reference dataset See more
TTTY10, Official Symbol TTTY10provided by HGNC Official Full Name testis expressed transcript, Y-linked 10provided by HGNC Primary source HGNC:HGNC:18491 See related Ensembl:ENSG00000229236 AllianceGenome:HGNC:18491 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY10; NCRNA00133 Expression Low expression observed in reference dataset See more
TTTY12, Official Symbol TTTY12provided by HGNC Official Full Name testis expressed transcript, Y-linked 12provided by HGNC Primary source HGNC:HGNC:18493 See related Ensembl:ENSG00000237048 AllianceGenome:HGNC:18493 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY11; TTY12; NCRNA00135 Expression Low expression observed in reference dataset See more
TTTY13, Official Symbol TTTY13provided by HGNC Official Full Name testis expressed transcript, Y-linked 13provided by HGNC Primary source HGNC:HGNC:18494 See related Ensembl:ENSG00000184991 AllianceGenome:HGNC:18494 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY13; NCRNA00136 Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
TTTY14, Official Symbol TTTY14provided by HGNC Official Full Name testis expressed transcript, Y-linked 14provided by HGNC Primary source HGNC:HGNC:18495 See related Ensembl:ENSG00000176728 AllianceGenome:HGNC:18495 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY14; CYorf14; PRO2834; NCRNA00137; NCRNA00185 Expression Low expression observed in reference dataset See more
TTTY17A, Official Symbol TTTY17Aprovided by HGNC Official Full Name testis expressed transcript, Y-linked 17Aprovided by HGNC Primary source HGNC:HGNC:18841 See related Ensembl:ENSG00000228240 MIM:400040; AllianceGenome:HGNC:18841 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTTY17; NCRNA00140 Summary There are three copies of this gene on chromosome Y. This record represents the most centromeric copy. [provided by RefSeq, Jul 2008]
TTTY17B, Official Symbol TTTY17Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 17Bprovided by HGNC Primary source HGNC:HGNC:31889 See related Ensembl:ENSG00000227439 AllianceGenome:HGNC:31889 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00141 Summary There are three copies of this gene on chromosome Y. This record represents the middle copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]
TTTY19, Official Symbol TTTY19provided by HGNC Official Full Name testis expressed transcript, Y-linked 19provided by HGNC Primary source HGNC:HGNC:18843 See related Ensembl:ENSG00000232419 AllianceGenome:HGNC:18843 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00144
TTTY1B, Official Symbol TTTY1Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 1Bprovided by HGNC Primary source HGNC:HGNC:37981 See related Ensembl:ENSG00000129816 AllianceGenome:HGNC:37981 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTTY1 Expression Low expression observed in reference dataset See more
TTTY2, Official Symbol TTTY2provided by HGNC Official Full Name testis expressed transcript, Y-linked 2provided by HGNC Primary source HGNC:HGNC:14023 See related AllianceGenome:HGNC:14023 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY2; lINC00109; NCRNA00109 Expression Biased expression in gall bladder (RPKM 3.9), testis (RPKM 1.4) and 1 other tissue See more
TTTY20, Official Symbol TTTY20provided by HGNC Official Full Name testis expressed transcript, Y-linked 20provided by HGNC Primary source HGNC:HGNC:18844 See related Ensembl:ENSG00000232808 AllianceGenome:HGNC:18844 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00145 Expression Low expression observed in reference dataset See more
TTTY21, Official Symbol TTTY21provided by HGNC Official Full Name testis expressed transcript, Y-linked 21provided by HGNC Primary source HGNC:HGNC:18845 See related Ensembl:ENSG00000228890 AllianceGenome:HGNC:18845 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00146 Expression Low expression observed in reference dataset See more
TTTY21B, Official Symbol TTTY21Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 21Bprovided by HGNC Primary source HGNC:HGNC:37980 See related AllianceGenome:HGNC:37980 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
TTTY22, Official Symbol TTTY22provided by HGNC Official Full Name testis expressed transcript, Y-linked 22provided by HGNC Primary source HGNC:HGNC:18846 See related Ensembl:ENSG00000224075 AllianceGenome:HGNC:18846 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00147 Expression Low expression observed in reference dataset See more
TTTY23, Official Symbol TTTY23provided by HGNC Official Full Name testis expressed transcript, Y-linked 23provided by HGNC Primary source HGNC:HGNC:18847 See related Ensembl:ENSG00000239225 AllianceGenome:HGNC:18847 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTTY23B; NCRNA00148 Expression Low expression observed in reference dataset See more
TTTY25P, Official Symbol TTTY25Pprovided by HGNC Official Full Name testis expressed transcript, Y-linked 25, pseudogeneprovided by HGNC Primary source HGNC:HGNC:38524 See related AllianceGenome:HGNC:38524 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TTTY3, Official Symbol TTTY3provided by HGNC Official Full Name testis expressed transcript, Y-linked 3provided by HGNC Primary source HGNC:HGNC:16480 See related Ensembl:ENSG00000231141 MIM:400036; AllianceGenome:HGNC:16480 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY3; TTTY3A; LINC00121; NCRNA00121 Summary There are two copies of this gene within the P1 palindrome on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]
TTTY3B, Official Symbol TTTY3Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 3Bprovided by HGNC Primary source HGNC:HGNC:31888 See related Ensembl:ENSG00000280961 AllianceGenome:HGNC:31888 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00122; LNCRNA00122 Summary There are two copies of this gene within the P1 palindrome on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]
TTTY4, Official Symbol TTTY4provided by HGNC Official Full Name testis expressed transcript, Y-linked 4provided by HGNC Primary source HGNC:HGNC:16481 See related Ensembl:ENSG00000226906 MIM:400037; AllianceGenome:HGNC:16481 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY4; TTTY4A; LINC00123; NCRNA00123 Summary There are three copies of this gene on chromosome Y. This record represents the most centromeric copy. [provided by RefSeq, Jul 2008]
TTTY4B, Official Symbol TTTY4Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 4Bprovided by HGNC Primary source HGNC:HGNC:31891 See related Ensembl:ENSG00000235412 AllianceGenome:HGNC:31891 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LINC00124; NCRNA00124 Summary There are three copies of this gene on chromosome Y. This record represents the middle copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]
TTTY4C, Official Symbol TTTY4Cprovided by HGNC Official Full Name testis expressed transcript, Y-linked 4Cprovided by HGNC Primary source HGNC:HGNC:31892 See related Ensembl:ENSG00000228296 AllianceGenome:HGNC:31892 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LINC00125; NCRNA00125 Summary There are three copies of this gene on chromosome Y. This record represents the most telomeric copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]
TTTY5, Official Symbol TTTY5provided by HGNC Official Full Name testis expressed transcript, Y-linked 5provided by HGNC Primary source HGNC:HGNC:16482 See related Ensembl:ENSG00000215560 MIM:400038; AllianceGenome:HGNC:16482 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY5; LINC00126; NCRNA00126 Summary There is a single copy of this gene on chromosome Y at the center of the P3 palindrome. [provided by RefSeq, Jul 2008]
TTTY6, Official Symbol TTTY6provided by HGNC Official Full Name testis expressed transcript, Y-linked 6provided by HGNC Primary source HGNC:HGNC:16483 See related Ensembl:ENSG00000131538 MIM:400039; AllianceGenome:HGNC:16483 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY6; TTTY6A; LINC00127; NCRNA00127 Summary There are two copies of this locus in the P3 palindrome on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]
TTTY6B, Official Symbol TTTY6Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 6Bprovided by HGNC Primary source HGNC:HGNC:31887 See related Ensembl:ENSG00000131548 AllianceGenome:HGNC:31887 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY6; TTTY6; LINC00128; NCRNA00128 Summary There are two copies of this locus in the P3 palindrome on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]
TTTY7, Official Symbol TTTY7provided by HGNC Official Full Name testis expressed transcript, Y-linked 7provided by HGNC Primary source HGNC:HGNC:18488 See related Ensembl:ENSG00000147753 AllianceGenome:HGNC:18488 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY7; TTTY7A; TTTY7B; LINC00129; NCRNA00129; CLONE795723 Expression Low expression observed in reference dataset See more
TTTY7B, Official Symbol TTTY7Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 7Bprovided by HGNC Primary source HGNC:HGNC:37463 See related Ensembl:ENSG00000147761 AllianceGenome:HGNC:37463 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCRNA00215 Expression Low expression observed in reference dataset See more
TTTY8, Official Symbol TTTY8provided by HGNC Official Full Name testis expressed transcript, Y-linked 8provided by HGNC Primary source HGNC:HGNC:18489 See related Ensembl:ENSG00000183385 AllianceGenome:HGNC:18489 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY8; LINC00130; NCRNA00130 Expression Low expression observed in reference dataset See more
TTTY8B, Official Symbol TTTY8Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 8Bprovided by HGNC Primary source HGNC:HGNC:37622 See related Ensembl:ENSG00000185700 AllianceGenome:HGNC:37622 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTTY8; NCRNA00217 Expression Low expression observed in reference dataset See more
TTTY9B, Official Symbol TTTY9Bprovided by HGNC Official Full Name testis expressed transcript, Y-linked 9Bprovided by HGNC Primary source HGNC:HGNC:32425 See related Ensembl:ENSG00000131007 AllianceGenome:HGNC:32425 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTY9; TTTY9; TTTY9A; NCRNA00132 Summary This gene is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region (P4) on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]
TTYH1, Official Symbol TTYH1provided by HGNC Official Full Name tweety family member 1provided by HGNC Primary source HGNC:HGNC:13476 See related Ensembl:ENSG00000167614 MIM:605784; AllianceGenome:HGNC:13476 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011] Expression Biased expression in brain (RPKM 71.7) and testis (RPKM 20.0) See more Orthologs mouse all
TTYH2, Official Symbol TTYH2provided by HGNC Official Full Name tweety family member 2provided by HGNC Primary source HGNC:HGNC:13877 See related Ensembl:ENSG00000141540 MIM:608855; AllianceGenome:HGNC:13877 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C17orf29 Summary This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 43.8), testis (RPKM 8.8) and 11 other tissues See more Orthologs mouse all
TTYH3, Official Symbol TTYH3provided by HGNC Official Full Name tweety family member 3provided by HGNC Primary source HGNC:HGNC:22222 See related Ensembl:ENSG00000136295 MIM:608919; AllianceGenome:HGNC:22222 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 20.5), kidney (RPKM 16.0) and 24 other tissues See more Orthologs mouse all
TUB, Official Symbol TUBprovided by HGNC Official Full Name TUB bipartite transcription factorprovided by HGNC Primary source HGNC:HGNC:12406 See related Ensembl:ENSG00000166402 MIM:601197; AllianceGenome:HGNC:12406 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as rd5; RDOB Summary This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 18.8), endometrium (RPKM 10.0) and 21 other tissues See more Orthologs mouse all
TUB-AS1, Official Symbol TUB-AS1provided by HGNC Official Full Name TUB antisense RNA 1provided by HGNC Primary source HGNC:HGNC:51120 See related Ensembl:ENSG00000248332 AllianceGenome:HGNC:51120 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
TUBA1A, Official Symbol TUBA1Aprovided by HGNC Official Full Name tubulin alpha 1aprovided by HGNC Primary source HGNC:HGNC:20766 See related Ensembl:ENSG00000167552 MIM:602529; AllianceGenome:HGNC:20766 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LIS3; TUBA3; B-ALPHA-1 Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in brain (RPKM 459.5), endometrium (RPKM 176.0) and 22 other tissues See more Orthologs mouse all
TUBA1B, Official Symbol TUBA1Bprovided by HGNC Official Full Name tubulin alpha 1bprovided by HGNC Primary source HGNC:HGNC:18809 See related Ensembl:ENSG00000123416 MIM:602530; AllianceGenome:HGNC:18809 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K-ALPHA-1 Summary Enables double-stranded RNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within cellular response to interleukin-4. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 600.4), bone marrow (RPKM 551.8) and 24 other tissues See more Orthologs mouse all
TUBA1C, Official Symbol TUBA1Cprovided by HGNC Official Full Name tubulin alpha 1cprovided by HGNC Primary source HGNC:HGNC:20768 See related Ensembl:ENSG00000167553 AllianceGenome:HGNC:20768 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBA6; bcm948 Summary Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in microtubule cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 168.9), bone marrow (RPKM 156.4) and 25 other tissues See more Orthologs mouse all
TUBA3C, Official Symbol TUBA3Cprovided by HGNC Official Full Name tubulin alpha 3cprovided by HGNC Primary source HGNC:HGNC:12408 See related Ensembl:ENSG00000198033 MIM:602528; AllianceGenome:HGNC:12408 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TUBA2; bA408E5.3 Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 241.8) See more Orthologs all
TUBA3D, Official Symbol TUBA3Dprovided by HGNC Official Full Name tubulin alpha 3dprovided by HGNC Primary source HGNC:HGNC:24071 See related Ensembl:ENSG00000075886 MIM:617878; AllianceGenome:HGNC:24071 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KTCN9; TUBA2; H2-ALPHA Summary This gene encodes a member of the alpha tubulin family. Tubulin is a major component of microtubules, which are composed of alpha- and beta-tubulin heterodimers and microtubule-associated proteins in the cytoskeleton. Microtubules maintain cellular structure, function in intracellular transport, and play a role in spindle formation during mitosis. [provided by RefSeq, Oct 2011] Expression Restricted expression toward testis (RPKM 122.6) See more Orthologs all
TUBA3E, Official Symbol TUBA3Eprovided by HGNC Official Full Name tubulin alpha 3eprovided by HGNC Primary source HGNC:HGNC:20765 See related Ensembl:ENSG00000152086 MIM:619918; AllianceGenome:HGNC:20765 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. This gene encodes an alpha tubulin that highly conserved among species. A missense mutation in this gene has been potentially linked to microlissencephaly and global developmental delay. [provided by RefSeq, Jul 2016] Expression Restricted expression toward testis (RPKM 55.9) See more Orthologs all
TUBA3FP, Official Symbol TUBA3FPprovided by HGNC Official Full Name tubulin alpha 3f pseudogeneprovided by HGNC Primary source HGNC:HGNC:24067 See related Ensembl:ENSG00000284130 AllianceGenome:HGNC:24067 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 2.0), brain (RPKM 1.0) and 20 other tissues See more
TUBA3GP, Official Symbol TUBA3GPprovided by HGNC Official Full Name tubulin alpha 3g pseudogeneprovided by HGNC Primary source HGNC:HGNC:44096 See related Ensembl:ENSG00000249680 AllianceGenome:HGNC:44096 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo