psui3905/ncbi_genes_summary huggingface dataset:
SYNJ2-IT1, Official Symbol SYNJ2-IT1provided by HGNC Official Full Name SYNJ2 intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41387 See related Ensembl:ENSG00000233496 AllianceGenome:HGNC:41387 Gene type ncRNA RefSeq status PREDICTED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
SYNJ2BP, Official Symbol SYNJ2BPprovided by HGNC Official Full Name synaptojanin 2 binding proteinprovided by HGNC Primary source HGNC:HGNC:18955 See related Ensembl:ENSG00000213463 MIM:609411; AllianceGenome:HGNC:18955 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARIP2; OMP25 Summary Predicted to enable type II activin receptor binding activity. Involved in several processes, including negative regulation of endothelial cell migration; negative regulation of sprouting angiogenesis; and regulation of signal transduction. Located in mitochondrion. Is integral component of mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 23.3), duodenum (RPKM 20.4) and 24 other tissues See more Orthologs mouse all
SYNJ2BP-COX16, Official Symbol SYNJ2BP-COX16provided by HGNC Official Full Name SYNJ2BP-COX16 readthroughprovided by HGNC Primary source HGNC:HGNC:48350 See related Ensembl:ENSG00000258644 AllianceGenome:HGNC:48350 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus represents naturally occurring read-through transcription between the neighboring SYNJ2BP (synaptojanin 2 binding protein) and COX16 (COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)) genes on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in kidney (RPKM 44.4), duodenum (RPKM 43.6) and 25 other tissues See more Orthologs all
SYNM, Official Symbol SYNMprovided by HGNC Official Full Name syneminprovided by HGNC Primary source HGNC:HGNC:24466 See related Ensembl:ENSG00000182253 MIM:606087; AllianceGenome:HGNC:24466 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DMN; SYN Summary The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 95.9), prostate (RPKM 82.3) and 15 other tissues See more Orthologs mouse all
SYNPO, Official Symbol SYNPOprovided by HGNC Official Full Name synaptopodinprovided by HGNC Primary source HGNC:HGNC:30672 See related Ensembl:ENSG00000171992 MIM:608155; AllianceGenome:HGNC:30672 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYNPO1 Summary Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008] Expression Broad expression in heart (RPKM 65.2), fat (RPKM 35.1) and 20 other tissues See more Orthologs mouse all
SYNPO2, Official Symbol SYNPO2provided by HGNC Official Full Name synaptopodin 2provided by HGNC Primary source HGNC:HGNC:17732 See related Ensembl:ENSG00000172403 AllianceGenome:HGNC:17732 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYISL Summary Enables alpha-actinin binding activity and filamin binding activity. Involved in positive regulation of actin filament bundle assembly; positive regulation of cell migration; and regulation of Rho-dependent protein serine/threonine kinase activity. Located in several cellular components, including Z disc; focal adhesion; and stress fiber. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 79.5), prostate (RPKM 71.0) and 14 other tissues See more Orthologs mouse all
SYNPO2L, Official Symbol SYNPO2Lprovided by HGNC Official Full Name synaptopodin 2 likeprovided by HGNC Primary source HGNC:HGNC:23532 See related Ensembl:ENSG00000166317 AllianceGenome:HGNC:23532 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable actin binding activity. Predicted to be involved in several processes, including positive regulation of Rho protein signal transduction; positive regulation of stress fiber assembly; and sarcomere organization. Located in cell junction; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward heart (RPKM 82.2) See more Orthologs mouse all
SYNPO2L-AS1, Official Symbol SYNPO2L-AS1provided by HGNC Official Full Name SYNPO2L antisense RNA 1provided by HGNC Primary source HGNC:HGNC:55242 See related AllianceGenome:HGNC:55242 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in heart (RPKM 6.3), prostate (RPKM 0.9) and 2 other tissues See more
SYNPR, Official Symbol SYNPRprovided by HGNC Official Full Name synaptoporinprovided by HGNC Primary source HGNC:HGNC:16507 See related Ensembl:ENSG00000163630 AllianceGenome:HGNC:16507 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPO Summary Predicted to be located in neuron projection and synaptic vesicle. Predicted to be integral component of membrane. Predicted to be active in synaptic vesicle membrane. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 14.4) See more Orthologs mouse all
SYNPR-AS1, Official Symbol SYNPR-AS1provided by HGNC Official Full Name SYNPR antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40774 See related Ensembl:ENSG00000241359 AllianceGenome:HGNC:40774 Gene type ncRNA RefSeq status PREDICTED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
SYNRG, Official Symbol SYNRGprovided by HGNC Official Full Name synergin gammaprovided by HGNC Primary source HGNC:HGNC:557 See related Ensembl:ENSG00000275066 MIM:607291; AllianceGenome:HGNC:557 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYNG; AP1GBP1 Summary This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 8.0), spleen (RPKM 6.7) and 25 other tissues See more Orthologs mouse all
SYP, Official Symbol SYPprovided by HGNC Official Full Name synaptophysinprovided by HGNC Primary source HGNC:HGNC:11506 See related Ensembl:ENSG00000102003 MIM:313475; AllianceGenome:HGNC:11506 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRX96; MRXSYP; XLID96 Summary This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017] Expression Biased expression in brain (RPKM 226.8) and adrenal (RPKM 21.1) See more Orthologs mouse all
SYP-AS1, Official Symbol SYP-AS1provided by HGNC Official Full Name SYP antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40571 See related Ensembl:ENSG00000237341 AllianceGenome:HGNC:40571 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in brain (RPKM 40.6) and adrenal (RPKM 3.4) See more
SYPL1, Official Symbol SYPL1provided by HGNC Official Full Name synaptophysin like 1provided by HGNC Primary source HGNC:HGNC:11507 See related Ensembl:ENSG00000008282 MIM:616665; AllianceGenome:HGNC:11507 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYPL; H-SP1 Summary Predicted to be involved in chemical synaptic transmission. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 63.3), esophagus (RPKM 56.9) and 25 other tissues See more Orthologs mouse all
SYPL1P1, Official Symbol SYPL1P1provided by HGNC Official Full Name synaptophysin like 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:53546 See related Ensembl:ENSG00000243154 AllianceGenome:HGNC:53546 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SYPL1P2, Official Symbol SYPL1P2provided by HGNC Official Full Name synaptophysin like 1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:53547 See related Ensembl:ENSG00000265683 AllianceGenome:HGNC:53547 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SYPL2, Official Symbol SYPL2provided by HGNC Official Full Name synaptophysin like 2provided by HGNC Primary source HGNC:HGNC:27638 See related Ensembl:ENSG00000143028 AllianceGenome:HGNC:27638 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MG29 Summary Involved in substantia nigra development. Predicted to be integral component of membrane. Predicted to be active in synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 4.9), testis (RPKM 4.8) and 20 other tissues See more Orthologs mouse all
SYS1, Official Symbol SYS1provided by HGNC Official Full Name SYS1 golgi trafficking proteinprovided by HGNC Primary source HGNC:HGNC:16162 See related Ensembl:ENSG00000204070 MIM:612979; AllianceGenome:HGNC:16162 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf169; dJ453C12.4; dJ453C12.4.1 Summary SYS1 forms a complex with ADP-ribosylation factor-related protein ARFRP1 (MIM 604699) and targets ARFRP1 to the Golgi apparatus (Behnia et al., 2004 [PubMed 15077113]).[supplied by OMIM, Aug 2009] Expression Ubiquitous expression in thyroid (RPKM 8.9), ovary (RPKM 6.7) and 25 other tissues See more Orthologs mouse all
SYS1-DBNDD2, Official Symbol SYS1-DBNDD2provided by HGNC Official Full Name SYS1-DBNDD2 readthrough (NMD candidate)provided by HGNC Primary source HGNC:HGNC:33535 See related Ensembl:ENSG00000254806 AllianceGenome:HGNC:33535 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf169-DBNDD2 Summary This locus represents naturally occurring read-through transcription from the neighboring SYS1 Golgi-localized integral membrane protein homolog and dysbindin domain containing 2 (DBNDD2) genes. The read-through transcript includes the majority of exons from each individual gene, but it would be subject to nonsense-mediated mRNA decay (NMD) and is therefore predicted to be non-coding. [provided by RefSeq, Oct 2010] Expression Broad expression in brain (RPKM 125.4), heart (RPKM 65.2) and 22 other tissues See more
SYT1, Official Symbol SYT1provided by HGNC Official Full Name synaptotagmin 1provided by HGNC Primary source HGNC:HGNC:11509 See related Ensembl:ENSG00000067715 MIM:185605; AllianceGenome:HGNC:11509 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P65; SYT; BAGOS; SVP65 Summary This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis. The encoded protein participates in triggering neurotransmitter release at the synapse in response to calcium binding. Mutations in this gene are associated with Baker-Gordon syndrome. [provided by RefSeq, Jan 2023] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s). Expression Biased expression in brain (RPKM 173.4) and adrenal (RPKM 11.7) See more Orthologs mouse all
SYT10, Official Symbol SYT10provided by HGNC Official Full Name synaptotagmin 10provided by HGNC Primary source HGNC:HGNC:19266 See related Ensembl:ENSG00000110975 AllianceGenome:HGNC:19266 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Predicted to be involved in several processes, including cellular response to calcium ion; regulation of secretion by cell; and sensory perception of smell. Predicted to be located in synapse and transport vesicle membrane. Predicted to be integral component of membrane. Predicted to be active in exocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
SYT11, Official Symbol SYT11provided by HGNC Official Full Name synaptotagmin 11provided by HGNC Primary source HGNC:HGNC:19239 See related Ensembl:ENSG00000132718 MIM:608741; AllianceGenome:HGNC:19239 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYT12; sytXI Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010] Annotation information Note: In 2002, the HUGO Gene Nomenclature Committee (HGNC) changed the official nomenclature of this locus to be standard with mouse and rat official nomenclature. Therefore, the gene previously known as "synaptotagmin XI" (SYT11, GeneID 23208) became "synaptotagmin XII" (SYT12) and "synaptotagmin XII" (SYT12, GeneID 91683) became "synaptotagmin XI" (SYT11). [13 Feb 2013] Expression Biased expression in brain (RPKM 160.9), adrenal (RPKM 11.8) and 1 other tissue See more Orthologs mouse all
SYT12, Official Symbol SYT12provided by HGNC Official Full Name synaptotagmin 12provided by HGNC Primary source HGNC:HGNC:18381 See related Ensembl:ENSG00000173227 MIM:606436; AllianceGenome:HGNC:18381 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYT11; sytXII Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010] Annotation information Note: In 2002, the HUGO Gene Nomenclature Committee (HGNC) changed the official nomenclature of this locus to be standard with mouse and rat official nomenclature. Therefore, the gene previously known as "synaptotagmin XI" (SYT11, GeneID 23208) became "synaptotagmin XII" (SYT12) and "synaptotagmin XII" (SYT12, GeneID 91683) became "synaptotagmin XI" (SYT11). [13 Feb 2013] Expression Biased expression in brain (RPKM 5.6), liver (RPKM 2.3) and 5 other tissues See more Orthologs mouse all
SYT13, Official Symbol SYT13provided by HGNC Official Full Name synaptotagmin 13provided by HGNC Primary source HGNC:HGNC:14962 See related Ensembl:ENSG00000019505 MIM:607716; AllianceGenome:HGNC:14962 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011] Expression Biased expression in brain (RPKM 27.1), gall bladder (RPKM 14.8) and 7 other tissues See more Orthologs mouse all
SYT14, Official Symbol SYT14provided by HGNC Official Full Name synaptotagmin 14provided by HGNC Primary source HGNC:HGNC:23143 See related Ensembl:ENSG00000143469 MIM:610949; AllianceGenome:HGNC:23143 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCAR11; sytXIV Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Dec 2011] Expression Biased expression in thyroid (RPKM 3.5), testis (RPKM 1.3) and 2 other tissues See more Orthologs mouse all
SYT15, Official Symbol SYT15provided by HGNC Official Full Name synaptotagmin 15provided by HGNC Primary source HGNC:HGNC:17167 See related Ensembl:ENSG00000204176 MIM:608081; AllianceGenome:HGNC:17167 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as sytXV; SYT15B; CHR10SYT Summary This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 8.5), lymph node (RPKM 2.1) and 18 other tissues See more Orthologs all
SYT16, Official Symbol SYT16provided by HGNC Official Full Name synaptotagmin 16provided by HGNC Primary source HGNC:HGNC:23142 See related Ensembl:ENSG00000139973 MIM:610950; AllianceGenome:HGNC:23142 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYT14L; syt14r; Strep14; CHR14SYT Summary Predicted to enable identical protein binding activity and phospholipid binding activity. Predicted to be involved in exocytosis. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 5.2), prostate (RPKM 0.7) and 2 other tissues See more Orthologs mouse all
SYT17, Official Symbol SYT17provided by HGNC Official Full Name synaptotagmin 17provided by HGNC Primary source HGNC:HGNC:24119 See related Ensembl:ENSG00000103528 AllianceGenome:HGNC:24119 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Syt-17; sytXVII Summary Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Predicted to be located in trans-Golgi network. Predicted to be active in exocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 8.9), prostate (RPKM 3.0) and 15 other tissues See more Orthologs mouse all
SYT2, Official Symbol SYT2provided by HGNC Official Full Name synaptotagmin 2provided by HGNC Primary source HGNC:HGNC:11510 See related Ensembl:ENSG00000143858 MIM:600104; AllianceGenome:HGNC:11510 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMS7; CMS7A; CMS7B; MYSPC; SytII Summary This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] Expression Broad expression in brain (RPKM 1.4), adrenal (RPKM 1.3) and 17 other tissues See more Orthologs mouse all
SYT3, Official Symbol SYT3provided by HGNC Official Full Name synaptotagmin 3provided by HGNC Primary source HGNC:HGNC:11511 See related Ensembl:ENSG00000213023 MIM:600327; AllianceGenome:HGNC:11511 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SytIII Summary Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Located in endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 3.3), testis (RPKM 0.5) and 3 other tissues See more Orthologs mouse all
SYT4, Official Symbol SYT4provided by HGNC Official Full Name synaptotagmin 4provided by HGNC Primary source HGNC:HGNC:11512 See related Ensembl:ENSG00000132872 MIM:600103; AllianceGenome:HGNC:11512 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HsT1192 Summary Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in negative regulation of catecholamine secretion and positive regulation of dendrite extension. Predicted to be located in several cellular components, including microvesicle; perinuclear region of cytoplasm; and secretory vesicle. Predicted to be active in several cellular components, including axon; exocytic vesicle; and glutamatergic synapse. Predicted to be integral component of neuronal dense core vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 34.8), adrenal (RPKM 10.3) and 1 other tissue See more Orthologs mouse all
SYT5, Official Symbol SYT5provided by HGNC Official Full Name synaptotagmin 5provided by HGNC Primary source HGNC:HGNC:11513 See related Ensembl:ENSG00000129990 MIM:600782; AllianceGenome:HGNC:11513 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011] Expression Biased expression in brain (RPKM 20.3) and adrenal (RPKM 2.1) See more Orthologs mouse all
SYT6, Official Symbol SYT6provided by HGNC Official Full Name synaptotagmin 6provided by HGNC Primary source HGNC:HGNC:18638 See related Ensembl:ENSG00000134207 MIM:607718; AllianceGenome:HGNC:18638 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as sytVI Summary The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in brain (RPKM 2.6), kidney (RPKM 0.8) and 6 other tissues See more Orthologs mouse all
SYT7, Official Symbol SYT7provided by HGNC Official Full Name synaptotagmin 7provided by HGNC Primary source HGNC:HGNC:11514 See related Ensembl:ENSG00000011347 MIM:604146; AllianceGenome:HGNC:11514 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] Expression Biased expression in brain (RPKM 15.4), prostate (RPKM 13.8) and 12 other tissues See more Orthologs mouse all
SYT8, Official Symbol SYT8provided by HGNC Official Full Name synaptotagmin 8provided by HGNC Primary source HGNC:HGNC:19264 See related Ensembl:ENSG00000149043 MIM:607719; AllianceGenome:HGNC:19264 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] Expression Biased expression in skin (RPKM 28.8), urinary bladder (RPKM 7.9) and 5 other tissues See more Orthologs mouse all
SYT9, Official Symbol SYT9provided by HGNC Official Full Name synaptotagmin 9provided by HGNC Primary source HGNC:HGNC:19265 See related Ensembl:ENSG00000170743 MIM:613528; AllianceGenome:HGNC:19265 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in calcium-ion regulated exocytosis; cellular response to calcium ion; and regulation of secretion by cell. Predicted to be located in clathrin-coated endocytic vesicle membrane. Predicted to be active in hippocampal mossy fiber to CA3 synapse; plasma membrane; and secretory vesicle. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 1.0), adrenal (RPKM 0.5) and 7 other tissues See more Orthologs mouse all
SYTL1, Official Symbol SYTL1provided by HGNC Official Full Name synaptotagmin like 1provided by HGNC Primary source HGNC:HGNC:15584 See related Ensembl:ENSG00000142765 MIM:608042; AllianceGenome:HGNC:15584 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JFC1; SLP1 Summary Predicted to enable neurexin family protein binding activity. Involved in exocytosis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in prostate (RPKM 24.6), skin (RPKM 21.7) and 16 other tissues See more Orthologs mouse all
SYTL2, Official Symbol SYTL2provided by HGNC Official Full Name synaptotagmin like 2provided by HGNC Primary source HGNC:HGNC:15585 See related Ensembl:ENSG00000137501 MIM:612880; AllianceGenome:HGNC:15585 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EXO4; SLP2; SLP2A; SGA72M; CHR11SYT; PPP1R151 Summary The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jun 2009] Expression Broad expression in stomach (RPKM 22.4), colon (RPKM 16.3) and 17 other tissues See more Orthologs mouse all
SYTL3, Official Symbol SYTL3provided by HGNC Official Full Name synaptotagmin like 3provided by HGNC Primary source HGNC:HGNC:15587 See related Ensembl:ENSG00000164674 AllianceGenome:HGNC:15587 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLP3 Summary The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in thyroid (RPKM 15.0), small intestine (RPKM 10.0) and 25 other tissues See more Orthologs mouse all
SYTL4, Official Symbol SYTL4provided by HGNC Official Full Name synaptotagmin like 4provided by HGNC Primary source HGNC:HGNC:15588 See related Ensembl:ENSG00000102362 MIM:300723; AllianceGenome:HGNC:15588 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLP4 Summary This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010] Expression Broad expression in ovary (RPKM 19.6), endometrium (RPKM 12.8) and 19 other tissues See more Orthologs mouse all
SYTL5, Official Symbol SYTL5provided by HGNC Official Full Name synaptotagmin like 5provided by HGNC Primary source HGNC:HGNC:15589 See related Ensembl:ENSG00000147041 AllianceGenome:HGNC:15589 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as slp5 Summary The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Broad expression in stomach (RPKM 4.3), placenta (RPKM 2.5) and 17 other tissues See more Orthologs mouse all
SYVN1, Official Symbol SYVN1provided by HGNC Official Full Name synoviolin 1provided by HGNC Primary source HGNC:HGNC:20738 See related Ensembl:ENSG00000162298 MIM:608046; AllianceGenome:HGNC:20738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DER3; HRD1 Summary This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011] Expression Ubiquitous expression in lymph node (RPKM 27.2), appendix (RPKM 21.7) and 25 other tissues See more Orthologs mouse all
SZRD1, Official Symbol SZRD1provided by HGNC Official Full Name SUZ RNA binding domain containing 1provided by HGNC Primary source HGNC:HGNC:30232 See related Ensembl:ENSG00000055070 AllianceGenome:HGNC:30232 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf144 Expression Ubiquitous expression in fat (RPKM 37.2), endometrium (RPKM 33.9) and 25 other tissues See more Orthologs mouse all
SZT2, Official Symbol SZT2provided by HGNC Official Full Name SZT2 subunit of KICSTOR complexprovided by HGNC Primary source HGNC:HGNC:29040 See related Ensembl:ENSG00000198198 MIM:615463; AllianceGenome:HGNC:29040 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE18; KICS1; SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467 Summary The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in ovary (RPKM 6.6), testis (RPKM 6.5) and 25 other tissues See more Orthologs mouse all
SZT2-AS1, Official Symbol SZT2-AS1provided by HGNC Official Full Name SZT2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41225 See related Ensembl:ENSG00000229372 AllianceGenome:HGNC:41225 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TAAR1, Official Symbol TAAR1provided by HGNC Official Full Name trace amine associated receptor 1provided by HGNC Primary source HGNC:HGNC:17734 See related Ensembl:ENSG00000146399 MIM:609333; AllianceGenome:HGNC:17734 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TA1; TAR1; TRAR1 Summary The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015] Orthologs mouse all
TAAR2, Official Symbol TAAR2provided by HGNC Official Full Name trace amine associated receptor 2provided by HGNC Primary source HGNC:HGNC:4514 See related Ensembl:ENSG00000146378 MIM:604849; AllianceGenome:HGNC:4514 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR58; taR-2 Summary Predicted to enable trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TAAR4P, Official Symbol TAAR4Pprovided by HGNC Official Full Name trace amine associated receptor 4, pseudogeneprovided by HGNC Primary source HGNC:HGNC:31924 See related Ensembl:ENSG00000237449 AllianceGenome:HGNC:31924 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable 2-phenylethylamine receptor activity. Predicted to be involved in behavioral fear response; chemosensory behavior; and sensory perception of chemical stimulus. [provided by Alliance of Genome Resources, Apr 2022]
TAAR5, Official Symbol TAAR5provided by HGNC Official Full Name trace amine associated receptor 5provided by HGNC Primary source HGNC:HGNC:30236 See related Ensembl:ENSG00000135569 MIM:607405; AllianceGenome:HGNC:30236 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PNR; taR-5 Summary Enables trimethylamine receptor activity. Predicted to be involved in signal transduction. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
TAAR6, Official Symbol TAAR6provided by HGNC Official Full Name trace amine associated receptor 6provided by HGNC Primary source HGNC:HGNC:20978 See related Ensembl:ENSG00000146383 MIM:608923; AllianceGenome:HGNC:20978 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TA4; TAR4; TAR6; TRAR4; taR-4; taR-6 Summary This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010] Orthologs mouse all
TAAR7P, Official Symbol TAAR7Pprovided by HGNC Official Full Name trace amine associated receptor 7, pseudogeneprovided by HGNC Primary source HGNC:HGNC:31925 See related Ensembl:ENSG00000235998 AllianceGenome:HGNC:31925 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
TAAR8, Official Symbol TAAR8provided by HGNC Official Full Name trace amine associated receptor 8provided by HGNC Primary source HGNC:HGNC:14964 See related Ensembl:ENSG00000146385 MIM:606927; AllianceGenome:HGNC:14964 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TA5; TAR5; TRAR5; TaR-5; TaR-8; GPR102 Summary This gene is part of the trace amine receptor cluster on chromosome 6 and encodes an orphan G-protein coupled receptor. Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain. [provided by RefSeq, Jul 2016] Orthologs all
TAAR9, Official Symbol TAAR9provided by HGNC Official Full Name trace amine associated receptor 9provided by HGNC Primary source HGNC:HGNC:20977 See related Ensembl:ENSG00000237110 MIM:608282; AllianceGenome:HGNC:20977 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TA3; TAR3; TAR9; TRAR3 Summary TAAR9 is a member of a large family of rhodopsin G protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Jul 2005] Annotation information Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Orthologs all