psui3905/ncbi_genes_summary huggingface dataset:
CLPB, Official Symbol CLPBprovided by HGNC Official Full Name ClpB family mitochondrial disaggregaseprovided by HGNC Primary source HGNC:HGNC:30664 See related Ensembl:ENSG00000162129 MIM:616254; AllianceGenome:HGNC:30664 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCN9; SKD3; HSP78; MGCA7; ANKCLB; ANKCLP; MGCA7A; MEGCANN Summary This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Expression Biased expression in testis (RPKM 59.2), brain (RPKM 5.3) and 5 other tissues See more Orthologs mouse all
CLPP, Official Symbol CLPPprovided by HGNC Official Full Name caseinolytic mitochondrial matrix peptidase proteolytic subunitprovided by HGNC Primary source HGNC:HGNC:2084 See related Ensembl:ENSG00000125656 MIM:601119; AllianceGenome:HGNC:2084 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB81; PRLTS3 Summary The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 19.9), fat (RPKM 18.0) and 25 other tissues See more Orthologs mouse all
CLPS, Official Symbol CLPSprovided by HGNC Official Full Name colipaseprovided by HGNC Primary source HGNC:HGNC:2085 See related Ensembl:ENSG00000137392 MIM:120105; AllianceGenome:HGNC:2085 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Restricted expression toward pancreas (RPKM 17741.6) See more Orthologs mouse all
CLPSL1, Official Symbol CLPSL1provided by HGNC Official Full Name colipase like 1provided by HGNC Primary source HGNC:HGNC:21251 See related Ensembl:ENSG00000204140 AllianceGenome:HGNC:21251 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ESP32; C6orf127; dJ510O8.6 Summary Predicted to enable enzyme activator activity. Predicted to be involved in response to food. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward pancreas (RPKM 4.4) See more Orthologs all
CLPSL2, Official Symbol CLPSL2provided by HGNC Official Full Name colipase like 2provided by HGNC Primary source HGNC:HGNC:21250 See related Ensembl:ENSG00000196748 AllianceGenome:HGNC:21250 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNQ3045; AAAL3045; C6orf126; dJ510O8.5 Summary Predicted to enable enzyme activator activity. Predicted to be involved in response to food. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
CLPTM1, Official Symbol CLPTM1provided by HGNC Official Full Name CLPTM1 regulator of GABA type A receptor forward traffickingprovided by HGNC Primary source HGNC:HGNC:2087 See related Ensembl:ENSG00000104853 MIM:604783; AllianceGenome:HGNC:2087 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in regulation of T cell differentiation in thymus. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 40.5), brain (RPKM 32.5) and 25 other tissues See more Orthologs mouse all
CLPTM1L, Official Symbol CLPTM1Lprovided by HGNC Official Full Name CLPTM1 likeprovided by HGNC Primary source HGNC:HGNC:24308 See related Ensembl:ENSG00000049656 MIM:612585; AllianceGenome:HGNC:24308 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRR9 Summary The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in testis (RPKM 35.1), thyroid (RPKM 34.7) and 25 other tissues See more Orthologs mouse all
CLPTM1LP1, Official Symbol CLPTM1LP1provided by HGNC Official Full Name CLPTM1L pseudogene 1provided by HGNC Primary source HGNC:HGNC:49023 See related Ensembl:ENSG00000271036 AllianceGenome:HGNC:49023 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CLPX, Official Symbol CLPXprovided by HGNC Official Full Name caseinolytic mitochondrial matrix peptidase chaperone subunit Xprovided by HGNC Primary source HGNC:HGNC:2088 See related Ensembl:ENSG00000166855 MIM:615611; AllianceGenome:HGNC:2088 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPP2 Summary The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in liver (RPKM 13.6), testis (RPKM 11.0) and 25 other tissues See more Orthologs mouse all
CLRN1, Official Symbol CLRN1provided by HGNC Official Full Name clarin 1provided by HGNC Primary source HGNC:HGNC:12605 See related Ensembl:ENSG00000163646 MIM:606397; AllianceGenome:HGNC:12605 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP61; USH3; USH3A Summary This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 2.0), duodenum (RPKM 0.5) and 1 other tissue See more Orthologs mouse all
CLRN2, Official Symbol CLRN2provided by HGNC Official Full Name clarin 2provided by HGNC Primary source HGNC:HGNC:33939 See related Ensembl:ENSG00000249581 MIM:618988; AllianceGenome:HGNC:33939 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB117 Summary This gene belongs to the clarin family of genes. The clarins appear to belong to a large superfamily of small integral membrane glycoproteins with four transmembrane domains. The exact function of this gene is unknown. [provided by RefSeq, Oct 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
CLRN3, Official Symbol CLRN3provided by HGNC Official Full Name clarin 3provided by HGNC Primary source HGNC:HGNC:20795 See related Ensembl:ENSG00000180745 MIM:620256; AllianceGenome:HGNC:20795 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TMEM12; USH3AL1 Summary Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in small intestine (RPKM 43.6), colon (RPKM 38.2) and 5 other tissues See more Orthologs mouse all
CLSPN, Official Symbol CLSPNprovided by HGNC Official Full Name claspinprovided by HGNC Primary source HGNC:HGNC:19715 See related Ensembl:ENSG00000092853 MIM:605434; AllianceGenome:HGNC:19715 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Expression Broad expression in bone marrow (RPKM 2.6), testis (RPKM 2.4) and 16 other tissues See more Orthologs mouse all
CLSTN1, Official Symbol CLSTN1provided by HGNC Official Full Name calsyntenin 1provided by HGNC Primary source HGNC:HGNC:17447 See related Ensembl:ENSG00000171603 MIM:611321; AllianceGenome:HGNC:17447 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2 Summary This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Ubiquitous expression in brain (RPKM 135.7), skin (RPKM 44.9) and 23 other tissues See more Orthologs mouse all
CLSTN2, Official Symbol CLSTN2provided by HGNC Official Full Name calsyntenin 2provided by HGNC Primary source HGNC:HGNC:17448 See related Ensembl:ENSG00000158258 MIM:611323; AllianceGenome:HGNC:17448 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CS2; CSTN2; CDHR13; ALC-GAMMA; alcagamma Summary Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to be located in postsynaptic density. Predicted to be active in cell surface; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in ovary (RPKM 37.4), brain (RPKM 15.7) and 6 other tissues See more Orthologs mouse all
CLSTN2-AS1, Official Symbol CLSTN2-AS1provided by HGNC Official Full Name CLSTN2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:49095 See related Ensembl:ENSG00000250433 AllianceGenome:HGNC:49095 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
CLSTN3, Official Symbol CLSTN3provided by HGNC Official Full Name calsyntenin 3provided by HGNC Primary source HGNC:HGNC:18371 See related Ensembl:ENSG00000139182 MIM:611324; AllianceGenome:HGNC:18371 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSTN3; CDHR14; alcbeta Summary Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within several processes, including chemical synaptic transmission; positive regulation of protein localization to synapse; and synapse assembly. Predicted to be located in postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 35.5), kidney (RPKM 13.1) and 23 other tissues See more Orthologs mouse all
CLTA, Official Symbol CLTAprovided by HGNC Official Full Name clathrin light chain Aprovided by HGNC Primary source HGNC:HGNC:2090 See related Ensembl:ENSG00000122705 MIM:118960; AllianceGenome:HGNC:2090 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCA Summary Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010] Expression Ubiquitous expression in colon (RPKM 66.3), kidney (RPKM 59.1) and 25 other tissues See more Orthologs mouse all
CLTB, Official Symbol CLTBprovided by HGNC Official Full Name clathrin light chain Bprovided by HGNC Primary source HGNC:HGNC:2091 See related Ensembl:ENSG00000175416 MIM:118970; AllianceGenome:HGNC:2091 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCB Summary Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 44.6), skin (RPKM 37.3) and 25 other tissues See more Orthologs mouse all
CLTC, Official Symbol CLTCprovided by HGNC Official Full Name clathrin heavy chainprovided by HGNC Primary source HGNC:HGNC:2092 See related Ensembl:ENSG00000141367 MIM:118955; AllianceGenome:HGNC:2092 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Hc; CHC; CHC17; MRD56; CLH-17; CLTCL2 Summary Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 67.0), thyroid (RPKM 49.4) and 25 other tissues See more Orthologs mouse all
CLTCL1, Official Symbol CLTCL1provided by HGNC Official Full Name clathrin heavy chain like 1provided by HGNC Primary source HGNC:HGNC:2093 See related Ensembl:ENSG00000070371 MIM:601273; AllianceGenome:HGNC:2093 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLTD; CHC22; CLH22; CLTCL Summary This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] Expression Biased expression in testis (RPKM 21.0), bone marrow (RPKM 6.6) and 8 other tissues See more Orthologs all
CLTRN, Official Symbol CLTRNprovided by HGNC Official Full Name collectrin, amino acid transport regulatorprovided by HGNC Primary source HGNC:HGNC:29437 See related Ensembl:ENSG00000147003 MIM:300631; AllianceGenome:HGNC:29437 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NX17; NX-17; TMEM27 Summary This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013] Expression Biased expression in kidney (RPKM 116.5) and liver (RPKM 8.9) See more Orthologs mouse all
CLU, Official Symbol CLUprovided by HGNC Official Full Name clusterinprovided by HGNC Primary source HGNC:HGNC:2095 See related Ensembl:ENSG00000120885 MIM:185430; AllianceGenome:HGNC:2095 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLI; AAG4; APOJ; CLU1; CLU2; KUB1; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2 Summary The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011] Expression Broad expression in brain (RPKM 523.1), liver (RPKM 432.6) and 16 other tissues See more Orthologs mouse all
CLUAP1, Official Symbol CLUAP1provided by HGNC Official Full Name clusterin associated protein 1provided by HGNC Primary source HGNC:HGNC:19009 See related Ensembl:ENSG00000103351 MIM:616787; AllianceGenome:HGNC:19009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAP22; IFT38; CFAP22 Summary The protein encoded by this gene contains a single coiled-coil region. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] Expression Broad expression in testis (RPKM 8.8), endometrium (RPKM 6.3) and 25 other tissues See more Orthologs mouse all
CLUH, Official Symbol CLUHprovided by HGNC Official Full Name clustered mitochondria homologprovided by HGNC Primary source HGNC:HGNC:29094 See related Ensembl:ENSG00000132361 MIM:616184; AllianceGenome:HGNC:29094 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLU1 Summary Enables mRNA binding activity. Involved in intracellular distribution of mitochondria. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 25.8), duodenum (RPKM 18.1) and 25 other tissues See more Orthologs mouse all
CLUHP10, Official Symbol CLUHP10provided by HGNC Official Full Name clustered mitochondria homolog pseudogene 10provided by HGNC Primary source HGNC:HGNC:51574 See related Ensembl:ENSG00000282511 AllianceGenome:HGNC:51574 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CLUHP4, Official Symbol CLUHP4provided by HGNC Official Full Name clustered mitochondria homolog pseudogene 4provided by HGNC Primary source HGNC:HGNC:38470 See related AllianceGenome:HGNC:38470 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA0664P4
CLUHP6, Official Symbol CLUHP6provided by HGNC Official Full Name clustered mitochondria homolog pseudogene 6provided by HGNC Primary source HGNC:HGNC:51571 See related Ensembl:ENSG00000265279 AllianceGenome:HGNC:51571 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
CLUL1, Official Symbol CLUL1provided by HGNC Official Full Name clusterin like 1provided by HGNC Primary source HGNC:HGNC:2096 See related Ensembl:ENSG00000079101 MIM:616990; AllianceGenome:HGNC:2096 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RA337M Summary Predicted to enable misfolded protein binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in prostate (RPKM 1.3), thyroid (RPKM 0.8) and 10 other tissues See more Orthologs all
CLVS1, Official Symbol CLVS1provided by HGNC Official Full Name clavesin 1provided by HGNC Primary source HGNC:HGNC:23139 See related Ensembl:ENSG00000177182 MIM:611292; AllianceGenome:HGNC:23139 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRALBPL; RLBP1L1; C6orf212L Summary Enables phosphatidylinositol-3,5-bisphosphate binding activity. Predicted to be involved in lysosome organization. Located in endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 24.7), adrenal (RPKM 7.1) and 18 other tissues See more Orthologs mouse all
CLVS2, Official Symbol CLVS2provided by HGNC Official Full Name clavesin 2provided by HGNC Primary source HGNC:HGNC:23046 See related Ensembl:ENSG00000146352 MIM:616945; AllianceGenome:HGNC:23046 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RLBP1L2; C6orf212; C6orf213; bA160A10.4 Summary This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes. [provided by RefSeq, Aug 2013] Expression Biased expression in brain (RPKM 3.1), prostate (RPKM 0.6) and 1 other tissue See more Orthologs mouse all
CLXN, Official Symbol CLXNprovided by HGNC Official Full Name calaxinprovided by HGNC Primary source HGNC:HGNC:25678 See related Ensembl:ENSG00000034239 MIM:619564; AllianceGenome:HGNC:25678 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ODAD5; EFCAB1 Summary Predicted to enable calcium ion binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 3.0), lung (RPKM 2.5) and 9 other tissues See more Orthologs mouse all
CLYBL, Official Symbol CLYBLprovided by HGNC Official Full Name citramalyl-CoA lyaseprovided by HGNC Primary source HGNC:HGNC:18355 See related Ensembl:ENSG00000125246 MIM:609686; AllianceGenome:HGNC:18355 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLB Summary Enables (S)-citramalyl-CoA lyase activity; magnesium ion binding activity; and malate synthase activity. Involved in protein homotrimerization and regulation of cobalamin metabolic process. Predicted to be located in mitochondrion. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 2.9), liver (RPKM 2.6) and 22 other tissues See more Orthologs mouse all
CLYBL-AS1, Official Symbol CLYBL-AS1provided by HGNC Official Full Name CLYBL antisense RNA 1provided by HGNC Primary source HGNC:HGNC:39893 See related Ensembl:ENSG00000234303 AllianceGenome:HGNC:39893 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 2.0) See more
CLYBL-AS2, Official Symbol CLYBL-AS2provided by HGNC Official Full Name CLYBL antisense RNA 2provided by HGNC Primary source HGNC:HGNC:39894 See related Ensembl:ENSG00000227659 AllianceGenome:HGNC:39894 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
CMA1, Official Symbol CMA1provided by HGNC Official Full Name chymase 1provided by HGNC Primary source HGNC:HGNC:2097 See related Ensembl:ENSG00000092009 MIM:118938; AllianceGenome:HGNC:2097 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CYH; MCT1; chymase Summary This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015] Expression Biased expression in colon (RPKM 6.3), esophagus (RPKM 4.1) and 11 other tissues See more Orthologs mouse all
CMAHP, Official Symbol CMAHPprovided by HGNC Official Full Name cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogeneprovided by HGNC Primary source HGNC:HGNC:2098 See related Ensembl:ENSG00000168405 MIM:603209; AllianceGenome:HGNC:2098 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMAH; CSAH Summary Sialic acids are terminal components of the carbohydrate chains of glycoconjugates involved in ligand-receptor, cell-cell, and cell-pathogen interactions. The two most common forms of sialic acid found in mammalian cells are N-acetylneuraminic acid (Neu5Ac) and its hydroxylated derivative, N-glycolylneuraminic acid (Neu5Gc). Studies of sialic acid distribution show that Neu5Gc is not detectable in normal human tissues although it was an abundant sialic acid in other mammals. Neu5Gc is, in actuality, immunogenic in humans. The absense of Neu5Gc in humans is due to a deletion within the human gene CMAH encoding cytidine monophosphate-N-acetylneuraminic acid hydroxylase, an enzyme responsible for Neu5Gc biosynthesis. Sequences encoding the mouse, pig, and chimpanzee hydroxylase enzymes were obtained by cDNA cloning and found to be highly homologous. However, the homologous human cDNA differs from these cDNAs by a 92-bp deletion in the 5' region. This deletion, corresponding to exon 6 of the mouse hydroxylase gene, causes a frameshift mutation and premature termination of the polypeptide chain in human. It seems unlikely that the truncated human hydroxylase mRNA encodes for an active enzyme explaining why Neu5Gc is undetectable in normal human tissues. Human genomic DNA also shows evidence of this deletion which does not occur in the genomes of African great apes. Nonetheless, the CMAH gene maps to 6p21.32 in humans and great apes indicating that mutation of the CMAH gene occurred following human divergence from chimpanzees and bonobos. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in skin (RPKM 10.5), lung (RPKM 9.3) and 23 other tissues See more
CMAS, Official Symbol CMASprovided by HGNC Official Full Name cytidine monophosphate N-acetylneuraminic acid synthetaseprovided by HGNC Primary source HGNC:HGNC:18290 See related Ensembl:ENSG00000111726 MIM:603316; AllianceGenome:HGNC:18290 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSS Summary This gene encodes an enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in testis (RPKM 46.2), colon (RPKM 38.5) and 25 other tissues See more Orthologs mouse all
CMBL, Official Symbol CMBLprovided by HGNC Official Full Name carboxymethylenebutenolidase homologprovided by HGNC Primary source HGNC:HGNC:25090 See related Ensembl:ENSG00000164237 MIM:613379; AllianceGenome:HGNC:25090 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JS-1 Summary CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010] Expression Biased expression in kidney (RPKM 81.9), duodenum (RPKM 43.0) and 10 other tissues See more Orthologs mouse all
CMC1, Official Symbol CMC1provided by HGNC Official Full Name C-X9-C motif containing 1provided by HGNC Primary source HGNC:HGNC:28783 See related Ensembl:ENSG00000187118 MIM:615166; AllianceGenome:HGNC:28783 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as cmc1p; C3orf68 Summary Predicted to enable metal ion binding activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 5.4), kidney (RPKM 3.5) and 25 other tissues See more Orthologs mouse all
CMC2, Official Symbol CMC2provided by HGNC Official Full Name C-X9-C motif containing 2provided by HGNC Primary source HGNC:HGNC:24447 See related Ensembl:ENSG00000103121 AllianceGenome:HGNC:24447 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DC13; C16orf61; 2310061C15Rik Summary Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 22.1), heart (RPKM 16.6) and 25 other tissues See more Orthologs mouse all
CMC4, Official Symbol CMC4provided by HGNC Official Full Name C-X9-C motif containing 4provided by HGNC Primary source HGNC:HGNC:35428 See related Ensembl:ENSG00000182712 MIM:301088; AllianceGenome:HGNC:35428 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p8; C6.1B; MTCP1; MTCP1B; MTCP1NB; p8MTCP1 Summary This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009] Annotation information Note: MTCP1 (Gene ID: 4515) and CMC4 (Gene ID: 100272147) share the MTCP1 symbol/alias in common. MTCP1 has been used as an alternative name for C-X9-C motif containing 4 (CMC4), which can be confused with the official symbol for mature T cell proliferation 1 (MTCP1). [06 Jul 2018] Note: Prior to build 37.1, geneID:4515 (MTCP1) was annotated as a single locus expressing transcripts with two distinct protein products. The locus was subsequently split into two geneIDs, with geneID:4515 representing the upstream locus (MTCP1, aka isoform p13) and geneID:100272147 representing the downstream locus (MTCP1NB, aka isoform p8). [13 Feb 2013] Expression Ubiquitous expression in heart (RPKM 14.9), fat (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
CMIP, Official Symbol CMIPprovided by HGNC Official Full Name c-Maf inducing proteinprovided by HGNC Primary source HGNC:HGNC:24319 See related Ensembl:ENSG00000153815 MIM:610112; AllianceGenome:HGNC:24319 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCMIP Summary This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in brain (RPKM 12.0), small intestine (RPKM 8.6) and 25 other tissues See more Orthologs mouse all
CMKLR1, Official Symbol CMKLR1provided by HGNC Official Full Name chemerin chemokine-like receptor 1provided by HGNC Primary source HGNC:HGNC:2121 See related Ensembl:ENSG00000174600 MIM:602351; AllianceGenome:HGNC:2121 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEZ; ERV1; RVER1; ChemR23; CHEMERINR Summary Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; positive regulation of macrophage chemotaxis; and regulation of calcium-mediated signaling. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 14.3), placenta (RPKM 10.1) and 22 other tissues See more Orthologs mouse all
CMPK1, Official Symbol CMPK1provided by HGNC Official Full Name cytidine/uridine monophosphate kinase 1provided by HGNC Primary source HGNC:HGNC:18170 See related Ensembl:ENSG00000162368 MIM:191710; AllianceGenome:HGNC:18170 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CK; CMK; UMK; CMPK; UMPK; UMP-CMPK Summary This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in colon (RPKM 74.1), duodenum (RPKM 71.2) and 25 other tissues See more Orthologs mouse all
CMPK2, Official Symbol CMPK2provided by HGNC Official Full Name cytidine/uridine monophosphate kinase 2provided by HGNC Primary source HGNC:HGNC:27015 See related Ensembl:ENSG00000134326 MIM:611787; AllianceGenome:HGNC:27015 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NDK; TYKi; TMPK2; UMP-CMPK2 Summary This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in bone marrow (RPKM 6.8), spleen (RPKM 4.2) and 23 other tissues See more Orthologs mouse all
CMSS1, Official Symbol CMSS1provided by HGNC Official Full Name cms1 ribosomal small subunit homologprovided by HGNC Primary source HGNC:HGNC:28666 See related Ensembl:ENSG00000184220 AllianceGenome:HGNC:28666 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C3orf26 Summary Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 15.9), adrenal (RPKM 15.4) and 25 other tissues See more Orthologs mouse all
CMTM1, Official Symbol CMTM1provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 1provided by HGNC Primary source HGNC:HGNC:19172 See related Ensembl:ENSG00000089505 MIM:607884; AllianceGenome:HGNC:19172 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKLFH; CKLFH1; CKLFSF1 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011] Expression Biased expression in testis (RPKM 16.1), spleen (RPKM 1.5) and 1 other tissue See more Orthologs mouse all
CMTM2, Official Symbol CMTM2provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 2provided by HGNC Primary source HGNC:HGNC:19173 See related Ensembl:ENSG00000140932 MIM:607885; AllianceGenome:HGNC:19173 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKLFSF2 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 259.5) See more Orthologs mouse all
CMTM3, Official Symbol CMTM3provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 3provided by HGNC Primary source HGNC:HGNC:19174 See related Ensembl:ENSG00000140931 MIM:607886; AllianceGenome:HGNC:19174 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BNAS2; CKLFSF3 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 24.7), placenta (RPKM 16.7) and 24 other tissues See more Orthologs mouse all
CMTM4, Official Symbol CMTM4provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 4provided by HGNC Primary source HGNC:HGNC:19175 See related Ensembl:ENSG00000183723 MIM:607887; AllianceGenome:HGNC:19175 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKLFSF4 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 48.0), kidney (RPKM 20.0) and 16 other tissues See more Orthologs mouse all
CMTM5, Official Symbol CMTM5provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 5provided by HGNC Primary source HGNC:HGNC:19176 See related Ensembl:ENSG00000166091 MIM:607888; AllianceGenome:HGNC:19176 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKLFSF5 Summary This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Expression Biased expression in brain (RPKM 15.6), bone marrow (RPKM 1.3) and 1 other tissue See more Orthologs mouse all