psui3905/ncbi_genes_summary huggingface dataset:
H3P34, Official Symbol H3P34provided by HGNC Official Full Name H3 histone pseudogene 34provided by HGNC Primary source HGNC:HGNC:54467 See related Ensembl:ENSG00000255295 AllianceGenome:HGNC:54467 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
H3P36, Official Symbol H3P36provided by HGNC Official Full Name H3 histone pseudogene 36provided by HGNC Primary source HGNC:HGNC:42030 See related Ensembl:ENSG00000236534 AllianceGenome:HGNC:42030 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p46; H3F3BP1
H3P37, Official Symbol H3P37provided by HGNC Official Full Name H3 histone pseudogene 37provided by HGNC Primary source HGNC:HGNC:19823 See related AllianceGenome:HGNC:19823 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p47; H3F3CP; H3F3AP2
H3P38, Official Symbol H3P38provided by HGNC Official Full Name H3 histone pseudogene 38provided by HGNC Primary source HGNC:HGNC:31028 See related AllianceGenome:HGNC:31028 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p48; H3F3AP1; HsT18159
H3P4, Official Symbol H3P4provided by HGNC Official Full Name H3 histone pseudogene 4provided by HGNC Primary source HGNC:HGNC:43797 See related AllianceGenome:HGNC:43797 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p05; HIST2H3DP1 Summary Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a transcribed histone pseudogene found on chromosome 1. [provided by RefSeq, Mar 2019]
H3P40, Official Symbol H3P40provided by HGNC Official Full Name H3 histone pseudogene 40provided by HGNC Primary source HGNC:HGNC:54470 See related AllianceGenome:HGNC:54470 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p50
H3P41, Official Symbol H3P41provided by HGNC Official Full Name H3 histone pseudogene 41provided by HGNC Primary source HGNC:HGNC:42979 See related Ensembl:ENSG00000265541 AllianceGenome:HGNC:42979 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p51; H3F3BP2
H3P42, Official Symbol H3P42provided by HGNC Official Full Name H3 histone pseudogene 42provided by HGNC Primary source HGNC:HGNC:54471 See related Ensembl:ENSG00000271626 AllianceGenome:HGNC:54471 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p52
H3P43, Official Symbol H3P43provided by HGNC Official Full Name H3 histone pseudogene 43provided by HGNC Primary source HGNC:HGNC:54472 See related Ensembl:ENSG00000226436 AllianceGenome:HGNC:54472 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p54
H3P45, Official Symbol H3P45provided by HGNC Official Full Name H3 histone pseudogene 45provided by HGNC Primary source HGNC:HGNC:54473 See related Ensembl:ENSG00000227211 AllianceGenome:HGNC:54473 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p56
H3P46, Official Symbol H3P46provided by HGNC Official Full Name H3 histone pseudogene 46provided by HGNC Primary source HGNC:HGNC:54474 See related Ensembl:ENSG00000278317 AllianceGenome:HGNC:54474 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
H3P7, Official Symbol H3P7provided by HGNC Official Full Name H3 histone pseudogene 7provided by HGNC Primary source HGNC:HGNC:43799 See related Ensembl:ENSG00000237178 AllianceGenome:HGNC:43799 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p60
H3P8, Official Symbol H3P8provided by HGNC Official Full Name H3 histone pseudogene 8provided by HGNC Primary source HGNC:HGNC:54449 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p14
H3Y2, Official Symbol H3Y2provided by HGNC Official Full Name H3.Y histone 2provided by HGNC Primary source HGNC:HGNC:43734 See related Ensembl:ENSG00000268799 AllianceGenome:HGNC:43734 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H3.X; H3.Y.2 Summary Predicted to enable DNA binding activity and protein heterodimerization activity. Part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
H4C1, Official Symbol H4C1provided by HGNC Official Full Name H4 clustered histone 1provided by HGNC Primary source HGNC:HGNC:4781 See related Ensembl:ENSG00000278637 MIM:602822; AllianceGenome:HGNC:4781 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FA; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4A Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs mouse all
H4C10P, Official Symbol H4C10Pprovided by HGNC Official Full Name H4 clustered histone 10, pseudogeneprovided by HGNC Primary source HGNC:HGNC:4786 See related AllianceGenome:HGNC:4786 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4FFP; pH4/f; dJ97D16.3; HIST1H4PS1 Summary Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This histone pseudogene is found in the small histone gene cluster on chromosome 6. [provided by RefSeq, Oct 2015]
H4C11, Official Symbol H4C11provided by HGNC Official Full Name H4 clustered histone 11provided by HGNC Primary source HGNC:HGNC:4785 See related Ensembl:ENSG00000197238 MIM:602826; AllianceGenome:HGNC:4785 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/e; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FE; H4-16; H4C12; H4C13; H4C14; H4C15; H4C16; H4F2iv; HIST1H4J; TEVANED2; TEBIVANED2; dJ160A22.2 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] Orthologs all
H4C12, Official Symbol H4C12provided by HGNC Official Full Name H4 clustered histone 12provided by HGNC Primary source HGNC:HGNC:4784 See related Ensembl:ENSG00000273542 MIM:602825; AllianceGenome:HGNC:4784 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/d; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FD; H4-16; H4C11; H4C13; H4C14; H4C15; H4C16; H4F2iii; HIST1H4K; dJ160A22.1 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
H4C13, Official Symbol H4C13provided by HGNC Official Full Name H4 clustered histone 13provided by HGNC Primary source HGNC:HGNC:4791 See related Ensembl:ENSG00000275126 MIM:602831; AllianceGenome:HGNC:4791 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4.k; H4/k; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FK; H4-16; H4C11; H4C12; H4C14; H4C15; H4C16; HIST1H4L Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] Orthologs all
H4C14, Official Symbol H4C14provided by HGNC Official Full Name H4 clustered histone 14provided by HGNC Primary source HGNC:HGNC:4794 See related Ensembl:ENSG00000270882 MIM:142750; AllianceGenome:HGNC:4794 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4; H4/n; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4F2; H4FN; FO108; H4-16; H4C11; H4C12; H4C13; H4C15; H4C16; HIST2H4; HIST2H4A Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015] Orthologs all
H4C15, Official Symbol H4C15provided by HGNC Official Full Name H4 clustered histone 15provided by HGNC Primary source HGNC:HGNC:29607 See related Ensembl:ENSG00000270276 AllianceGenome:HGNC:29607 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/o; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4-16; H4C11; H4C12; H4C13; H4C14; H4C16; HIST2H4B Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H4 family. Some transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, May 2020] Orthologs all
H4C2, Official Symbol H4C2provided by HGNC Official Full Name H4 clustered histone 2provided by HGNC Primary source HGNC:HGNC:4789 See related Ensembl:ENSG00000278705 MIM:602829; AllianceGenome:HGNC:4789 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/I; H4C1; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FI; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4B Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C3, Official Symbol H4C3provided by HGNC Official Full Name H4 clustered histone 3provided by HGNC Primary source HGNC:HGNC:4787 See related Ensembl:ENSG00000197061 MIM:602827; AllianceGenome:HGNC:4787 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/g; H4C1; H4C2; H4C4; H4C5; H4C6; H4C8; H4C9; H4FG; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4C; TEVANED1; TEBIVANED1; dJ221C16.1 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs mouse all
H4C4, Official Symbol H4C4provided by HGNC Official Full Name H4 clustered histone 4provided by HGNC Primary source HGNC:HGNC:4782 See related Ensembl:ENSG00000277157 MIM:602823; AllianceGenome:HGNC:4782 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/b; H4C1; H4C2; H4C3; H4C5; H4C6; H4C8; H4C9; H4FB; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4D; dJ221C16.9 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C5, Official Symbol H4C5provided by HGNC Official Full Name H4 clustered histone 5provided by HGNC Primary source HGNC:HGNC:4790 See related Ensembl:ENSG00000276966 MIM:602830; AllianceGenome:HGNC:4790 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/j; H4C1; H4C2; H4C3; H4C4; H4C6; H4C8; H4C9; H4FJ; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4E; TEVANED3; TEBIVANED3 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C6, Official Symbol H4C6provided by HGNC Official Full Name H4 clustered histone 6provided by HGNC Primary source HGNC:HGNC:4783 See related Ensembl:ENSG00000274618 MIM:602824; AllianceGenome:HGNC:4783 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4; H4/c; H4C1; H4C2; H4C3; H4C4; H4C5; H4C8; H4C9; H4FC; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4F Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C7, Official Symbol H4C7provided by HGNC Official Full Name H4 clustered histone 7provided by HGNC Primary source HGNC:HGNC:4792 See related Ensembl:ENSG00000275663 MIM:602832; AllianceGenome:HGNC:4792 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/l; H4FL; HIST1H4G Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C8, Official Symbol H4C8provided by HGNC Official Full Name H4 clustered histone 8provided by HGNC Primary source HGNC:HGNC:4788 See related Ensembl:ENSG00000158406 MIM:602828; AllianceGenome:HGNC:4788 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4/h; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C9; H4FH; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4H Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] Orthologs all
H4C9, Official Symbol H4C9provided by HGNC Official Full Name H4 clustered histone 9provided by HGNC Primary source HGNC:HGNC:4793 See related Ensembl:ENSG00000276180 MIM:602833; AllianceGenome:HGNC:4793 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4M; H4/m; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4FM; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4I; TEVANED4; TEBIVANED4 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015] Orthologs mouse all
H4P1, Official Symbol H4P1provided by HGNC Official Full Name H4 histone pseudogene 1provided by HGNC Primary source HGNC:HGNC:54447 See related Ensembl:ENSG00000240680 AllianceGenome:HGNC:54447 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
H6PD, Official Symbol H6PDprovided by HGNC Official Full Name hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:4795 See related Ensembl:ENSG00000049239 MIM:138090; AllianceGenome:HGNC:4795 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GDH; G6PDH; H6PDH; CORTRD1 Summary There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 12.8), skin (RPKM 11.6) and 25 other tissues See more Orthologs mouse all
HAAO, Official Symbol HAAOprovided by HGNC Official Full Name 3-hydroxyanthranilate 3,4-dioxygenaseprovided by HGNC Primary source HGNC:HGNC:4796 See related Ensembl:ENSG00000162882 MIM:604521; AllianceGenome:HGNC:4796 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HAO; 3-HAO; VCRL1; h3HAO Summary 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 28.1), kidney (RPKM 12.5) and 13 other tissues See more Orthologs mouse all
HABP2, Official Symbol HABP2provided by HGNC Official Full Name hyaluronan binding protein 2provided by HGNC Primary source HGNC:HGNC:4798 See related Ensembl:ENSG00000148702 MIM:603924; AllianceGenome:HGNC:4798 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FSAP; HABP; PHBP; HGFAL; NMTC5 Summary This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] Expression Biased expression in liver (RPKM 158.0), gall bladder (RPKM 23.3) and 1 other tissue See more Orthologs mouse all
HABP4, Official Symbol HABP4provided by HGNC Official Full Name hyaluronan binding protein 4provided by HGNC Primary source HGNC:HGNC:17062 See related Ensembl:ENSG00000130956 MIM:617369; AllianceGenome:HGNC:17062 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IHABP4; IHABP-4; Ki-1/57; SERBP1L Summary Enables SUMO binding activity. Involved in PML body organization; negative regulation of DNA binding activity; and positive regulation of gene expression. Located in several cellular components, including Golgi apparatus; cytoplasmic stress granule; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 24.4), testis (RPKM 16.9) and 22 other tissues See more Orthologs mouse all
HACD1, Official Symbol HACD1provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 1provided by HGNC Primary source HGNC:HGNC:9639 See related Ensembl:ENSG00000165996 MIM:610467; AllianceGenome:HGNC:9639 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAP; MYONP; PTPLA; CMYP11 Summary The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 20.1), prostate (RPKM 5.4) and 14 other tissues See more Orthologs mouse all
HACD2, Official Symbol HACD2provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 2provided by HGNC Primary source HGNC:HGNC:9640 See related Ensembl:ENSG00000206527 MIM:615939; AllianceGenome:HGNC:9640 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTPLB Summary The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in fat (RPKM 34.0), prostate (RPKM 10.4) and 24 other tissues See more Orthologs mouse all
HACD3, Official Symbol HACD3provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 3provided by HGNC Primary source HGNC:HGNC:24175 See related Ensembl:ENSG00000074696 MIM:615940; AllianceGenome:HGNC:24175 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIND1; B-IND1; HSPC121; PTPLAD1 Summary Enables 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Involved in fatty acid biosynthetic process; positive regulation by virus of viral protein levels in host cell; and positive regulation of viral genome replication. Located in endoplasmic reticulum and nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 49.9), adrenal (RPKM 46.4) and 25 other tissues See more Orthologs mouse all
HACD4, Official Symbol HACD4provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 4provided by HGNC Primary source HGNC:HGNC:20920 See related Ensembl:ENSG00000188921 MIM:615941; AllianceGenome:HGNC:20920 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTPLAD2 Summary Enables 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Involved in fatty acid elongation and very long-chain fatty acid biosynthetic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lung (RPKM 8.9), bone marrow (RPKM 8.0) and 23 other tissues See more Orthologs mouse all
HACE1, Official Symbol HACE1provided by HGNC Official Full Name HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1provided by HGNC Primary source HGNC:HGNC:21033 See related Ensembl:ENSG00000085382 MIM:610876; AllianceGenome:HGNC:21033 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPPRS Summary This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016] Expression Broad expression in placenta (RPKM 13.5), testis (RPKM 6.0) and 22 other tissues See more Orthologs mouse all
HACL1, Official Symbol HACL1provided by HGNC Official Full Name 2-hydroxyacyl-CoA lyase 1provided by HGNC Primary source HGNC:HGNC:17856 See related Ensembl:ENSG00000131373 MIM:604300; AllianceGenome:HGNC:17856 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPCL; HPCL2; PHYH2; 2-HPCL Summary Enables several functions, including 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity; ATP binding activity; and cation binding activity. Involved in fatty acid alpha-oxidation; phytanic acid metabolic process; and protein targeting to peroxisome. Located in nucleoplasm and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 25.3), testis (RPKM 14.8) and 25 other tissues See more Orthologs mouse all
HADH, Official Symbol HADHprovided by HGNC Official Full Name hydroxyacyl-CoA dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:4799 See related Ensembl:ENSG00000138796 MIM:601609; AllianceGenome:HGNC:4799 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD Summary This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010] Expression Ubiquitous expression in fat (RPKM 86.5), kidney (RPKM 61.3) and 24 other tissues See more Orthologs mouse all
HADHA, Official Symbol HADHAprovided by HGNC Official Full Name hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alphaprovided by HGNC Primary source HGNC:HGNC:4801 See related Ensembl:ENSG00000084754 MIM:600890; AllianceGenome:HGNC:4801 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GBP; ECHA; HADH; LCEH; MTPA; LCHAD; TP-ALPHA Summary This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in duodenum (RPKM 119.6), small intestine (RPKM 107.2) and 25 other tissues See more Orthologs mouse all
HADHAP1, Official Symbol HADHAP1provided by HGNC Official Full Name HADHA pseudogene 1provided by HGNC Primary source HGNC:HGNC:4802 See related Ensembl:ENSG00000251596 AllianceGenome:HGNC:4802 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HADHAP
HADHB, Official Symbol HADHBprovided by HGNC Official Full Name hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit betaprovided by HGNC Primary source HGNC:HGNC:4803 See related Ensembl:ENSG00000138029 MIM:143450; AllianceGenome:HGNC:4803 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ECHB; MTPB; MTPD; MTPD2; MSTP029; TP-BETA Summary This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in heart (RPKM 140.9), duodenum (RPKM 87.4) and 25 other tissues See more Orthologs mouse all
HADHBP1, Official Symbol HADHBP1provided by HGNC Official Full Name HADHB pseudogene 1provided by HGNC Primary source HGNC:HGNC:54887 See related Ensembl:ENSG00000238193 AllianceGenome:HGNC:54887 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
HAGH, Official Symbol HAGHprovided by HGNC Official Full Name hydroxyacylglutathione hydrolaseprovided by HGNC Primary source HGNC:HGNC:4805 See related Ensembl:ENSG00000063854 MIM:138760; AllianceGenome:HGNC:4805 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLO2; GLX2; GLXII; HAGH1 Summary The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] Expression Broad expression in kidney (RPKM 47.0), liver (RPKM 45.0) and 25 other tissues See more Orthologs mouse all
HAGHL, Official Symbol HAGHLprovided by HGNC Official Full Name hydroxyacylglutathione hydrolase likeprovided by HGNC Primary source HGNC:HGNC:14177 See related Ensembl:ENSG00000103253 AllianceGenome:HGNC:14177 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 1.8), spleen (RPKM 1.6) and 20 other tissues See more Orthologs mouse all
HAGLR, Official Symbol HAGLRprovided by HGNC Official Full Name HOXD antisense growth-associated long non-coding RNAprovided by HGNC Primary source HGNC:HGNC:43755 See related Ensembl:ENSG00000224189 MIM:618209; AllianceGenome:HGNC:43755 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Mdgt; STEEL; HOXD-AS1; MIR7704HG Expression Biased expression in testis (RPKM 20.0), lung (RPKM 8.2) and 9 other tissues See more Orthologs mouse all
HAGLROS, Official Symbol HAGLROSprovided by HGNC Official Full Name HAGLR opposite strand lncRNAprovided by HGNC Primary source HGNC:HGNC:50646 See related AllianceGenome:HGNC:50646 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in colon (RPKM 1.2), testis (RPKM 1.1) and 14 other tissues See more Orthologs mouse all
HAL, Official Symbol HALprovided by HGNC Official Full Name histidine ammonia-lyaseprovided by HGNC Primary source HGNC:HGNC:4806 See related Ensembl:ENSG00000084110 MIM:609457; AllianceGenome:HGNC:4806 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIS; HSTD Summary Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in skin (RPKM 20.5), liver (RPKM 18.5) and 2 other tissues See more Orthologs mouse all
HAMP, Official Symbol HAMPprovided by HGNC Official Full Name hepcidin antimicrobial peptideprovided by HGNC Primary source HGNC:HGNC:15598 See related Ensembl:ENSG00000105697 MIM:606464; AllianceGenome:HGNC:15598 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEPC; PLTR; HFE2B; LEAP1 Summary The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014] Expression Biased expression in liver (RPKM 88.9) and heart (RPKM 10.6) See more Orthologs mouse all