psui3905/ncbi_genes_summary huggingface dataset:
PCNX2, Official Symbol PCNX2provided by HGNC Official Full Name pecanex 2provided by HGNC Primary source HGNC:HGNC:8736 See related Ensembl:ENSG00000135749 MIM:617656; AllianceGenome:HGNC:8736 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCNXL2 Summary This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas. [provided by RefSeq, Jun 2016] Expression Ubiquitous expression in brain (RPKM 5.2), ovary (RPKM 2.2) and 22 other tissues See more Orthologs mouse all
PCNX3, Official Symbol PCNX3provided by HGNC Official Full Name pecanex 3provided by HGNC Primary source HGNC:HGNC:18760 See related Ensembl:ENSG00000197136 MIM:617657; AllianceGenome:HGNC:18760 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCNXL3 Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 9.4), spleen (RPKM 6.0) and 25 other tissues See more Orthologs mouse all
PCNX4, Official Symbol PCNX4provided by HGNC Official Full Name pecanex 4provided by HGNC Primary source HGNC:HGNC:20349 See related Ensembl:ENSG00000126773 AllianceGenome:HGNC:20349 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBP2; PCNXL4; C14orf135 Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 4.7), endometrium (RPKM 4.5) and 25 other tissues See more Orthologs mouse all
PCOLCE, Official Symbol PCOLCEprovided by HGNC Official Full Name procollagen C-endopeptidase enhancerprovided by HGNC Primary source HGNC:HGNC:8738 See related Ensembl:ENSG00000106333 MIM:600270; AllianceGenome:HGNC:8738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCPE; PCPE1; PCPE-1 Summary Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in gall bladder (RPKM 64.6), endometrium (RPKM 44.2) and 21 other tissues See more Orthologs mouse all
PCOLCE-AS1, Official Symbol PCOLCE-AS1provided by HGNC Official Full Name PCOLCE antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40430 See related Ensembl:ENSG00000224729 AllianceGenome:HGNC:40430 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 11.3), fat (RPKM 4.1) and 20 other tissues See more
PCOLCE2, Official Symbol PCOLCE2provided by HGNC Official Full Name procollagen C-endopeptidase enhancer 2provided by HGNC Primary source HGNC:HGNC:8739 See related Ensembl:ENSG00000163710 MIM:607064; AllianceGenome:HGNC:8739 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCPE2 Summary Enables collagen binding activity; heparin binding activity; and peptidase activator activity. Predicted to be involved in positive regulation of peptidase activity. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in fat (RPKM 75.7), heart (RPKM 31.8) and 9 other tissues See more Orthologs mouse all
PCOTH, Official Symbol PCOTHprovided by HGNC Official Full Name prostate and testis expressed opposite C1QTNF9B and MIPEPprovided by HGNC Primary source HGNC:HGNC:39839 See related Ensembl:ENSG00000205861 MIM:617122; AllianceGenome:HGNC:39839 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1QTNF9B-AS1 Summary Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 11.5), prostate (RPKM 9.5) and 14 other tissues See more Orthologs all
PCP2, Official Symbol PCP2provided by HGNC Official Full Name Purkinje cell protein 2provided by HGNC Primary source HGNC:HGNC:30209 See related Ensembl:ENSG00000174788 MIM:619344; AllianceGenome:HGNC:30209 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCD5; GPSM4 Summary Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within rhodopsin mediated signaling pathway. Predicted to be located in neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 11.4), salivary gland (RPKM 2.1) and 8 other tissues See more Orthologs mouse all
PCP4, Official Symbol PCP4provided by HGNC Official Full Name Purkinje cell protein 4provided by HGNC Primary source HGNC:HGNC:8742 See related Ensembl:ENSG00000183036 MIM:601629; AllianceGenome:HGNC:8742 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEP-19 Summary Enables calcium ion binding activity and calmodulin binding activity. Involved in calmodulin dependent kinase signaling pathway and positive regulation of neuron differentiation. Located in cytosol and nucleus. Part of protein-containing complex. Biomarker of Huntington's disease and leiomyoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in prostate (RPKM 108.8), urinary bladder (RPKM 73.3) and 6 other tissues See more Orthologs mouse all
PCP4L1, Official Symbol PCP4L1provided by HGNC Official Full Name Purkinje cell protein 4 like 1provided by HGNC Primary source HGNC:HGNC:20448 See related Ensembl:ENSG00000248485 AllianceGenome:HGNC:20448 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IQM1 Expression Biased expression in urinary bladder (RPKM 16.5), brain (RPKM 14.3) and 10 other tissues See more Orthologs mouse all
PCSEAT, Official Symbol PCSEATprovided by HGNC Official Full Name prostate cancer expressed EZH2 associated transcriptprovided by HGNC Primary source HGNC:HGNC:54485 See related Ensembl:ENSG00000286027 AllianceGenome:HGNC:54485 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRCAT38 Expression Low expression observed in reference dataset See more
PCSK1, Official Symbol PCSK1provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 1provided by HGNC Primary source HGNC:HGNC:8743 See related Ensembl:ENSG00000175426 MIM:162150; AllianceGenome:HGNC:8743 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC1; PC3; NEC1; SPC3; PC1/3; BMIQ12 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Jan 2014] Expression Biased expression in brain (RPKM 13.3), adrenal (RPKM 3.9) and 6 other tissues See more Orthologs mouse all
PCSK1N, Official Symbol PCSK1Nprovided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 1 inhibitorprovided by HGNC Primary source HGNC:HGNC:17301 See related Ensembl:ENSG00000102109 MIM:300399; AllianceGenome:HGNC:17301 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEN; SAAS; SCG8; BigLEN; SgVIII; PROSAAS Summary The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013] Expression Biased expression in kidney (RPKM 101.8), brain (RPKM 31.9) and 2 other tissues See more Orthologs mouse all
PCSK2, Official Symbol PCSK2provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 2provided by HGNC Primary source HGNC:HGNC:8744 See related Ensembl:ENSG00000125851 MIM:162151; AllianceGenome:HGNC:8744 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC2; NEC2; SPC2; NEC 2; NEC-2 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The protein undergoes an initial autocatalytic processing event and interacts with a neuroendocrine secretory protein in the ER, exits the ER and sorts to secretory granules, where it is cleaved and catalytically activated during intracellular transport. The encoded protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2014] Expression Biased expression in adrenal (RPKM 14.5), brain (RPKM 10.5) and 9 other tissues See more Orthologs mouse all
PCSK4, Official Symbol PCSK4provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 4provided by HGNC Primary source HGNC:HGNC:8746 See related Ensembl:ENSG00000115257 MIM:600487; AllianceGenome:HGNC:8746 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC4; SPC5 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. [provided by RefSeq, Jan 2014] Expression Biased expression in testis (RPKM 19.7) and kidney (RPKM 0.9) See more Orthologs mouse all
PCSK5, Official Symbol PCSK5provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 5provided by HGNC Primary source HGNC:HGNC:8747 See related Ensembl:ENSG00000099139 MIM:600488; AllianceGenome:HGNC:8747 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC5; PC6; PC6A; SPC6 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B). [provided by RefSeq, May 2014] Expression Broad expression in small intestine (RPKM 6.4), duodenum (RPKM 5.8) and 20 other tissues See more Orthologs mouse all
PCSK6, Official Symbol PCSK6provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 6provided by HGNC Primary source HGNC:HGNC:8569 See related Ensembl:ENSG00000140479 MIM:167405; AllianceGenome:HGNC:8569 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPC4; PACE4 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014] Expression Biased expression in spleen (RPKM 31.3), liver (RPKM 30.7) and 12 other tissues See more Orthologs mouse all
PCSK6-AS1, Official Symbol PCSK6-AS1provided by HGNC Official Full Name PCSK6 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:51448 See related Ensembl:ENSG00000259764 AllianceGenome:HGNC:51448 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
PCSK7, Official Symbol PCSK7provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 7provided by HGNC Primary source HGNC:HGNC:8748 See related Ensembl:ENSG00000160613 MIM:604872; AllianceGenome:HGNC:8748 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LPC; PC7; PC8; SPC7 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Feb 2014] Expression Ubiquitous expression in endometrium (RPKM 37.0), urinary bladder (RPKM 33.8) and 25 other tissues See more Orthologs mouse all
PCSK9, Official Symbol PCSK9provided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 9provided by HGNC Primary source HGNC:HGNC:20001 See related Ensembl:ENSG00000169174 MIM:607786; AllianceGenome:HGNC:20001 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FH3; PC9; FHCL3; NARC1; LDLCQ1; NARC-1; HCHOLA3 Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Expression Biased expression in lung (RPKM 5.3), liver (RPKM 3.3) and 9 other tissues See more Orthologs mouse all
PCTP, Official Symbol PCTPprovided by HGNC Official Full Name phosphatidylcholine transfer proteinprovided by HGNC Primary source HGNC:HGNC:8752 See related Ensembl:ENSG00000141179 MIM:606055; AllianceGenome:HGNC:8752 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC-TP; STARD2 Summary Enables phosphatidylcholine binding activity and phosphatidylcholine transporter activity. Involved in phospholipid transport. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in liver (RPKM 9.3), placenta (RPKM 5.2) and 24 other tissues See more Orthologs mouse all
PCYOX1, Official Symbol PCYOX1provided by HGNC Official Full Name prenylcysteine oxidase 1provided by HGNC Primary source HGNC:HGNC:20588 See related Ensembl:ENSG00000116005 MIM:610995; AllianceGenome:HGNC:20588 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCL1 Summary Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in fat (RPKM 61.1), kidney (RPKM 49.9) and 23 other tissues See more Orthologs mouse all
PCYOX1L, Official Symbol PCYOX1Lprovided by HGNC Official Full Name prenylcysteine oxidase 1 likeprovided by HGNC Primary source HGNC:HGNC:28477 See related Ensembl:ENSG00000145882 AllianceGenome:HGNC:28477 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable prenylcysteine oxidase activity. Predicted to be involved in prenylated protein catabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.8), brain (RPKM 5.2) and 24 other tissues See more Orthologs mouse all
PCYT1A, Official Symbol PCYT1Aprovided by HGNC Official Full Name phosphate cytidylyltransferase 1A, cholineprovided by HGNC Primary source HGNC:HGNC:8754 See related Ensembl:ENSG00000161217 MIM:123695; AllianceGenome:HGNC:8754 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT; CTA; CCTA; CTPCT; PCYT1; SMDCRD; CCTalpha Summary This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in duodenum (RPKM 22.3), small intestine (RPKM 20.1) and 25 other tissues See more Orthologs mouse all
PCYT1B, Official Symbol PCYT1Bprovided by HGNC Official Full Name phosphate cytidylyltransferase 1B, cholineprovided by HGNC Primary source HGNC:HGNC:8755 See related Ensembl:ENSG00000102230 MIM:300948; AllianceGenome:HGNC:8755 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTB; CCTB Summary The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Biased expression in brain (RPKM 6.6), testis (RPKM 2.8) and 7 other tissues See more Orthologs mouse all
PCYT1B-AS1, Official Symbol PCYT1B-AS1provided by HGNC Official Full Name PCYT1B antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40431 See related Ensembl:ENSG00000236836 AllianceGenome:HGNC:40431 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
PCYT2, Official Symbol PCYT2provided by HGNC Official Full Name phosphate cytidylyltransferase 2, ethanolamineprovided by HGNC Primary source HGNC:HGNC:8756 See related Ensembl:ENSG00000185813 MIM:602679; AllianceGenome:HGNC:8756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ET; SPG82 Summary This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Broad expression in testis (RPKM 31.9), duodenum (RPKM 10.8) and 22 other tissues See more Orthologs mouse all
PDAP1, Official Symbol PDAP1provided by HGNC Official Full Name PDGFA associated protein 1provided by HGNC Primary source HGNC:HGNC:14634 See related Ensembl:ENSG00000106244 MIM:607075; AllianceGenome:HGNC:14634 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP; PAP1; HASPP28 Summary The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in fat (RPKM 24.9), colon (RPKM 23.3) and 25 other tissues See more Orthologs mouse all
PDC, Official Symbol PDCprovided by HGNC Official Full Name phosducinprovided by HGNC Primary source HGNC:HGNC:8759 See related Ensembl:ENSG00000116703 MIM:171490; AllianceGenome:HGNC:8759 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHD; MEKA; PhLP; PhLOP Summary This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
PDC-AS1, Official Symbol PDC-AS1provided by HGNC Official Full Name PDC antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40432 See related Ensembl:ENSG00000229739 AllianceGenome:HGNC:40432 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
PDCD1, Official Symbol PDCD1provided by HGNC Official Full Name programmed cell death 1provided by HGNC Primary source HGNC:HGNC:8760 See related Ensembl:ENSG00000188389 MIM:600244; AllianceGenome:HGNC:8760 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 Summary Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] Expression Biased expression in lymph node (RPKM 8.8), spleen (RPKM 2.6) and 7 other tissues See more Orthologs mouse all
PDCD10, Official Symbol PDCD10provided by HGNC Official Full Name programmed cell death 10provided by HGNC Primary source HGNC:HGNC:8761 See related Ensembl:ENSG00000114209 MIM:609118; AllianceGenome:HGNC:8761 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCM3; TFAR15 Summary This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 13.1), lymph node (RPKM 11.6) and 25 other tissues See more Orthologs mouse all
PDCD11, Official Symbol PDCD11provided by HGNC Official Full Name programmed cell death 11provided by HGNC Primary source HGNC:HGNC:13408 See related Ensembl:ENSG00000148843 MIM:612333; AllianceGenome:HGNC:13408 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALG4; NFBP; RRP5; ALG-4 Summary PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008] Expression Ubiquitous expression in testis (RPKM 12.3), skin (RPKM 7.7) and 25 other tissues See more Orthologs mouse all
PDCD1LG2, Official Symbol PDCD1LG2provided by HGNC Official Full Name programmed cell death 1 ligand 2provided by HGNC Primary source HGNC:HGNC:18731 See related Ensembl:ENSG00000197646 MIM:605723; AllianceGenome:HGNC:18731 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2 Summary Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 7.3), lymph node (RPKM 5.3) and 21 other tissues See more Orthologs mouse all
PDCD2, Official Symbol PDCD2provided by HGNC Official Full Name programmed cell death 2provided by HGNC Primary source HGNC:HGNC:8762 See related Ensembl:ENSG00000071994 MIM:600866; AllianceGenome:HGNC:8762 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP8; ZMYND7 Summary This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in lymph node (RPKM 7.8), thyroid (RPKM 7.5) and 25 other tissues See more Orthologs mouse all
PDCD2L, Official Symbol PDCD2Lprovided by HGNC Official Full Name programmed cell death 2 likeprovided by HGNC Primary source HGNC:HGNC:28194 See related Ensembl:ENSG00000126249 MIM:615661; AllianceGenome:HGNC:28194 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 7.2), fat (RPKM 2.8) and 25 other tissues See more Orthologs mouse all
PDCD4, Official Symbol PDCD4provided by HGNC Official Full Name programmed cell death 4provided by HGNC Primary source HGNC:HGNC:8763 See related Ensembl:ENSG00000150593 MIM:608610; AllianceGenome:HGNC:8763 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H731 Summary This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in colon (RPKM 80.4), thyroid (RPKM 70.8) and 25 other tissues See more Orthologs mouse all
PDCD5, Official Symbol PDCD5provided by HGNC Official Full Name programmed cell death 5provided by HGNC Primary source HGNC:HGNC:8764 See related Ensembl:ENSG00000105185 MIM:604583; AllianceGenome:HGNC:8764 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TFAR19 Summary This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in testis (RPKM 17.5), adrenal (RPKM 13.5) and 25 other tissues See more Orthologs mouse all
PDCD6, Official Symbol PDCD6provided by HGNC Official Full Name programmed cell death 6provided by HGNC Primary source HGNC:HGNC:8765 See related Ensembl:ENSG00000249915 MIM:601057; AllianceGenome:HGNC:8765 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALG2; ALG-2; PEF1B Summary This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012] Annotation information Note: ALG2 (Gene ID: 85365) and PDCD6 (Gene ID: 10016) share the ALG2 symbol/alias in common. ALG2 is a widely used alternative name for programmed cell death 6 (PDCD6), whose synonym is apoptosis-linked gene-2. This can be confused with the official symbol for ALG2, alpha-1,3/1,6-mannosyltransferase (ALG2). [31 May 2018] Expression Ubiquitous expression in colon (RPKM 23.5), adrenal (RPKM 21.4) and 25 other tissues See more Orthologs mouse all
PDCD6IP, Official Symbol PDCD6IPprovided by HGNC Official Full Name programmed cell death 6 interacting proteinprovided by HGNC Primary source HGNC:HGNC:8766 See related Ensembl:ENSG00000170248 MIM:608074; AllianceGenome:HGNC:8766 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIP1; ALIX; HP95; DRIP4; MCPH29 Summary This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] Expression Ubiquitous expression in colon (RPKM 28.2), esophagus (RPKM 23.0) and 25 other tissues See more Orthologs mouse all
PDCD6IP-DT, Official Symbol PDCD6IP-DTprovided by HGNC Official Full Name PDCD6IP divergent transcriptprovided by HGNC Primary source HGNC:HGNC:55244 See related Ensembl:ENSG00000271643 AllianceGenome:HGNC:55244 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in thyroid (RPKM 1.9), testis (RPKM 1.5) and 25 other tissues See more
PDCD6IPP1, Official Symbol PDCD6IPP1provided by HGNC Official Full Name PDCD6IP pseudogene 1provided by HGNC Primary source HGNC:HGNC:49872 See related Ensembl:ENSG00000275325 AllianceGenome:HGNC:49872 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCD7, Official Symbol PDCD7provided by HGNC Official Full Name programmed cell death 7provided by HGNC Primary source HGNC:HGNC:8767 See related Ensembl:ENSG00000090470 MIM:608138; AllianceGenome:HGNC:8767 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 59K; ES18; HES18 Summary This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in testis (RPKM 10.7), ovary (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
PDCL, Official Symbol PDCLprovided by HGNC Official Full Name phosducin likeprovided by HGNC Primary source HGNC:HGNC:8770 See related Ensembl:ENSG00000136940 MIM:604421; AllianceGenome:HGNC:8770 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PhLP Summary Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 5.5), lung (RPKM 5.2) and 25 other tissues See more Orthologs mouse all
PDCL2, Official Symbol PDCL2provided by HGNC Official Full Name phosducin like 2provided by HGNC Primary source HGNC:HGNC:29524 See related Ensembl:ENSG00000163440 MIM:611676; AllianceGenome:HGNC:29524 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCPHLP Summary This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 13.2) See more Orthologs mouse all
PDCL2P1, Official Symbol PDCL2P1provided by HGNC Official Full Name PDCL2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:50340 See related Ensembl:ENSG00000228610 AllianceGenome:HGNC:50340 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL2P2, Official Symbol PDCL2P2provided by HGNC Official Full Name PDCL2 pseudogene 2provided by HGNC Primary source HGNC:HGNC:50341 See related Ensembl:ENSG00000255058 AllianceGenome:HGNC:50341 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL3, Official Symbol PDCL3provided by HGNC Official Full Name phosducin like 3provided by HGNC Primary source HGNC:HGNC:28860 See related Ensembl:ENSG00000115539 MIM:611678; AllianceGenome:HGNC:28860 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A Summary This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in appendix (RPKM 9.1), esophagus (RPKM 8.2) and 25 other tissues See more Orthologs mouse all
PDCL3P1, Official Symbol PDCL3P1provided by HGNC Official Full Name PDCL3 pseudogene 1provided by HGNC Primary source HGNC:HGNC:31826 See related AllianceGenome:HGNC:31826 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL3P4, Official Symbol PDCL3P4provided by HGNC Official Full Name PDCL3 pseudogene 4provided by HGNC Primary source HGNC:HGNC:44505 See related AllianceGenome:HGNC:44505 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL3P5, Official Symbol PDCL3P5provided by HGNC Official Full Name PDCL3 pseudogene 5provided by HGNC Primary source HGNC:HGNC:44506 See related AllianceGenome:HGNC:44506 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL3P6, Official Symbol PDCL3P6provided by HGNC Official Full Name PDCL3 pseudogene 6provided by HGNC Primary source HGNC:HGNC:44507 See related Ensembl:ENSG00000224255 AllianceGenome:HGNC:44507 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
PDCL3P7, Official Symbol PDCL3P7provided by HGNC Official Full Name PDCL3 pseudogene 7provided by HGNC Primary source HGNC:HGNC:44508 See related Ensembl:ENSG00000256777 AllianceGenome:HGNC:44508 Gene type pseudo RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo