psui3905/ncbi_genes_summary huggingface dataset:
SSX2B, Official Symbol SSX2Bprovided by HGNC Official Full Name SSX family member 2Bprovided by HGNC Primary source HGNC:HGNC:22263 See related Ensembl:ENSG00000268447 AllianceGenome:HGNC:22263 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSX; CT5.2; CT5.2b; HOM-MEL-40 Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013] Expression Restricted expression toward testis (RPKM 18.4) See more
SSX2IP, Official Symbol SSX2IPprovided by HGNC Official Full Name SSX family member 2 interacting proteinprovided by HGNC Primary source HGNC:HGNC:16509 See related Ensembl:ENSG00000117155 MIM:608690; AllianceGenome:HGNC:16509 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADIP; hMsd1 Summary This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] Expression Broad expression in testis (RPKM 29.1), duodenum (RPKM 14.3) and 19 other tissues See more Orthologs mouse all
SSX3, Official Symbol SSX3provided by HGNC Official Full Name SSX family member 3provided by HGNC Primary source HGNC:HGNC:11337 See related Ensembl:ENSG00000165584 MIM:300325; AllianceGenome:HGNC:11337 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT5.3 Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. [provided by RefSeq, Jul 2013] Expression Restricted expression toward testis (RPKM 5.8) See more Orthologs all
SSX4, Official Symbol SSX4provided by HGNC Official Full Name SSX family member 4provided by HGNC Primary source HGNC:HGNC:11338 See related Ensembl:ENSG00000268009 MIM:300326; AllianceGenome:HGNC:11338 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT5.4 Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 3.3) See more Orthologs all
SSX4B, Official Symbol SSX4Bprovided by HGNC Official Full Name SSX family member 4Bprovided by HGNC Primary source HGNC:HGNC:16880 See related Ensembl:ENSG00000269791 AllianceGenome:HGNC:16880 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT5.4 Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 3.3) See more Orthologs all
SSX5, Official Symbol SSX5provided by HGNC Official Full Name SSX family member 5provided by HGNC Primary source HGNC:HGNC:11339 See related Ensembl:ENSG00000165583 MIM:300327; AllianceGenome:HGNC:11339 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2013] Expression Low expression observed in reference dataset See more
SSX7, Official Symbol SSX7provided by HGNC Official Full Name SSX family member 7provided by HGNC Primary source HGNC:HGNC:19653 See related Ensembl:ENSG00000187754 MIM:300542; AllianceGenome:HGNC:19653 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs all
ST13, Official Symbol ST13provided by HGNC Official Full Name ST13 Hsp70 interacting proteinprovided by HGNC Primary source HGNC:HGNC:11343 See related Ensembl:ENSG00000100380 MIM:606796; AllianceGenome:HGNC:11343 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIP; HOP; P48; AAG2; SNC6; HSPABP; FAM10A1; FAM10A4; HSPABP1; PRO0786 Summary The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] Expression Ubiquitous expression in ovary (RPKM 177.9), kidney (RPKM 97.3) and 25 other tissues See more Orthologs mouse all
ST13P12, Official Symbol ST13P12provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 12provided by HGNC Primary source HGNC:HGNC:38787 See related Ensembl:ENSG00000248400 AllianceGenome:HGNC:38787 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P15, Official Symbol ST13P15provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 15provided by HGNC Primary source HGNC:HGNC:38850 See related Ensembl:ENSG00000243759 AllianceGenome:HGNC:38850 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P16, Official Symbol ST13P16provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 16provided by HGNC Primary source HGNC:HGNC:38851 See related AllianceGenome:HGNC:38851 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P18, Official Symbol ST13P18provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 18provided by HGNC Primary source HGNC:HGNC:38861 See related AllianceGenome:HGNC:38861 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P2, Official Symbol ST13P2provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 2provided by HGNC Primary source HGNC:HGNC:38716 See related AllianceGenome:HGNC:38716 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P20, Official Symbol ST13P20provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 20provided by HGNC Primary source HGNC:HGNC:38863 See related Ensembl:ENSG00000215875 AllianceGenome:HGNC:38863 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST13P6, Official Symbol ST13P6provided by HGNC Official Full Name ST13, Hsp70 interacting protein pseudogene 6provided by HGNC Primary source HGNC:HGNC:18557 See related AllianceGenome:HGNC:18557 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM10A6; FAM10A6P
ST14, Official Symbol ST14provided by HGNC Official Full Name ST14 transmembrane serine protease matriptaseprovided by HGNC Primary source HGNC:HGNC:11344 See related Ensembl:ENSG00000149418 MIM:606797; AllianceGenome:HGNC:11344 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HAI; CAP3; MTSP1; SNC19; ARCI11; MT-SP1; PRSS14; TADG15; TMPRSS14 Summary The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 103.0), small intestine (RPKM 72.7) and 15 other tissues See more Orthologs mouse all
ST18, Official Symbol ST18provided by HGNC Official Full Name ST18 C2H2C-type zinc finger transcription factorprovided by HGNC Primary source HGNC:HGNC:18695 See related Ensembl:ENSG00000147488 MIM:617155; AllianceGenome:HGNC:18695 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NZF3; NZF-3; ZNF387; ZC2H2C3; ZC2HC10 Summary Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of nitrogen compound metabolic process. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 3.7), stomach (RPKM 0.7) and 3 other tissues See more Orthologs mouse all
ST20, Official Symbol ST20provided by HGNC Official Full Name suppressor of tumorigenicity 20provided by HGNC Primary source HGNC:HGNC:33520 See related Ensembl:ENSG00000180953 AllianceGenome:HGNC:33520 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCCS-1 Summary Enables cysteine-type endopeptidase activator activity involved in apoptotic process. Involved in several processes, including apoptotic signaling pathway; cellular response to UV-C; and positive regulation of nitrogen compound metabolic process. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 2.1), appendix (RPKM 2.1) and 24 other tissues See more Orthologs all
ST20-MTHFS, Official Symbol ST20-MTHFSprovided by HGNC Official Full Name ST20-MTHFS readthroughprovided by HGNC Primary source HGNC:HGNC:44655 See related Ensembl:ENSG00000259332 AllianceGenome:HGNC:44655 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MTHFS Summary This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010] Expression Broad expression in liver (RPKM 20.4), kidney (RPKM 11.5) and 23 other tissues See more
ST3GAL1, Official Symbol ST3GAL1provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:10862 See related Ensembl:ENSG00000008513 MIM:607187; AllianceGenome:HGNC:10862 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST3O; SIAT4A; SIATFL; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalA.1; ST3GalIA,1 Summary The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 30.7), kidney (RPKM 13.0) and 22 other tissues See more Orthologs mouse all
ST3GAL2, Official Symbol ST3GAL2provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 2provided by HGNC Primary source HGNC:HGNC:10863 See related Ensembl:ENSG00000157350 MIM:607188; AllianceGenome:HGNC:10863 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT4B; ST3GALII; Gal-NAc6S; ST3GalA.2 Summary The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in appendix (RPKM 6.9), spleen (RPKM 6.8) and 24 other tissues See more Orthologs mouse all
ST3GAL3, Official Symbol ST3GAL3provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 3provided by HGNC Primary source HGNC:HGNC:10866 See related Ensembl:ENSG00000126091 MIM:606494; AllianceGenome:HGNC:10866 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST3N; DEE15; MRT12; SIAT6; EIEE15; ST3GALII; ST3GalIII; ST3Gal III Summary The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] Expression Broad expression in testis (RPKM 4.7), fat (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
ST3GAL3-AS1, Official Symbol ST3GAL3-AS1provided by HGNC Official Full Name ST3GAL3 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40529 See related Ensembl:ENSG00000229444 AllianceGenome:HGNC:40529 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ST3GAL4, Official Symbol ST3GAL4provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 4provided by HGNC Primary source HGNC:HGNC:10864 See related Ensembl:ENSG00000110080 MIM:104240; AllianceGenome:HGNC:10864 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STZ; SAT3; ST-4; CGS23; SIAT4; NANTA3; SIAT4C; ST3GalIV; ST3GalA.2; gal-NAc6S Summary This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Broad expression in adrenal (RPKM 20.2), ovary (RPKM 18.9) and 23 other tissues See more Orthologs mouse all
ST3GAL5, Official Symbol ST3GAL5provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 5provided by HGNC Primary source HGNC:HGNC:10872 See related Ensembl:ENSG00000115525 MIM:604402; AllianceGenome:HGNC:10872 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SATI; SIAT9; SPDRS; ST3GalV; SIATGM3S; ST3Gal V Summary Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in adrenal (RPKM 17.6), thyroid (RPKM 16.1) and 23 other tissues See more Orthologs mouse all
ST3GAL5-AS1, Official Symbol ST3GAL5-AS1provided by HGNC Official Full Name ST3GAL5 antisense RNA 1 (head to head)provided by HGNC Primary source HGNC:HGNC:51129 See related AllianceGenome:HGNC:51129 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in thyroid (RPKM 1.8), brain (RPKM 0.8) and 15 other tissues See more
ST3GAL6, Official Symbol ST3GAL6provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 6provided by HGNC Primary source HGNC:HGNC:18080 See related Ensembl:ENSG00000064225 MIM:607156; AllianceGenome:HGNC:18080 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT10; ST3GALVI Summary The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016] Expression Broad expression in heart (RPKM 8.2), liver (RPKM 7.6) and 24 other tissues See more Orthologs mouse all
ST3GAL6-AS1, Official Symbol ST3GAL6-AS1provided by HGNC Official Full Name ST3GAL6 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40828 See related AllianceGenome:HGNC:40828 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in heart (RPKM 1.5), fat (RPKM 1.3) and 20 other tissues See more
ST6GAL1, Official Symbol ST6GAL1provided by HGNC Official Full Name ST6 beta-galactoside alpha-2,6-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:10860 See related Ensembl:ENSG00000073849 MIM:109675; AllianceGenome:HGNC:10860 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST6N; CDw75; SIAT1; ST6GalI Summary This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] Expression Broad expression in liver (RPKM 87.7), lymph node (RPKM 37.8) and 18 other tissues See more Orthologs mouse all
ST6GAL2, Official Symbol ST6GAL2provided by HGNC Official Full Name ST6 beta-galactoside alpha-2,6-sialyltransferase 2provided by HGNC Primary source HGNC:HGNC:10861 See related Ensembl:ENSG00000144057 MIM:608472; AllianceGenome:HGNC:10861 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT2; ST6GalII Summary This locus encodes a sialyltransferase. The encoded type II transmembrane protein catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. Polymorphisms at this locus may be associated with variations in risperidone response in schizophrenic patients. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] Expression Biased expression in thyroid (RPKM 11.0), brain (RPKM 3.9) and 3 other tissues See more Orthologs mouse all
ST6GALNAC1, Official Symbol ST6GALNAC1provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:23614 See related Ensembl:ENSG00000070526 MIM:610138; AllianceGenome:HGNC:23614 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STYI; SIAT7A; HSY11339; ST6GalNAcI Summary Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008] Expression Biased expression in colon (RPKM 93.3), small intestine (RPKM 34.8) and 7 other tissues See more Orthologs all
ST6GALNAC2, Official Symbol ST6GALNAC2provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2provided by HGNC Primary source HGNC:HGNC:10867 See related Ensembl:ENSG00000070731 MIM:610137; AllianceGenome:HGNC:10867 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STHM; SIAT7; SAITL1; SIAT7B; SIATL1; ST6GalNAII Summary ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008] Expression Broad expression in testis (RPKM 18.1), skin (RPKM 16.6) and 18 other tissues See more Orthologs mouse all
ST6GALNAC2P1, Official Symbol ST6GALNAC2P1provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 pseudogene 1provided by HGNC Primary source HGNC:HGNC:45160 See related Ensembl:ENSG00000228902 AllianceGenome:HGNC:45160 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST6GALNAC3, Official Symbol ST6GALNAC3provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3provided by HGNC Primary source HGNC:HGNC:19343 See related Ensembl:ENSG00000184005 MIM:610133; AllianceGenome:HGNC:19343 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STY; SIAT7C; PRO7177; ST6GALNACIII Summary ST6GALNAC3 belongs to a family of sialyltransferases that transfer sialic acids from CMP-sialic acid to terminal positions of carbohydrate groups in glycoproteins and glycolipids (Lee et al., 1999 [PubMed 10207017]).[supplied by OMIM, Mar 2008] Expression Broad expression in thyroid (RPKM 2.3), kidney (RPKM 1.6) and 19 other tissues See more Orthologs mouse all
ST6GALNAC4, Official Symbol ST6GALNAC4provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4provided by HGNC Primary source HGNC:HGNC:17846 See related Ensembl:ENSG00000136840 MIM:606378; AllianceGenome:HGNC:17846 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IV; SIAT3C; SIAT7D; SIAT3-C; SIAT7-D; ST6GalNAc; ST6GALNACIV Summary The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene. [provided by RefSeq, Jan 2022] Expression Ubiquitous expression in bone marrow (RPKM 14.6), spleen (RPKM 9.7) and 24 other tissues See more Orthologs mouse all
ST6GALNAC4P1, Official Symbol ST6GALNAC4P1provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 pseudogene 1provided by HGNC Primary source HGNC:HGNC:39660 See related Ensembl:ENSG00000233469 AllianceGenome:HGNC:39660 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
ST6GALNAC5, Official Symbol ST6GALNAC5provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5provided by HGNC Primary source HGNC:HGNC:19342 See related Ensembl:ENSG00000117069 MIM:610134; AllianceGenome:HGNC:19342 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT7E; SIAT7-E; ST6GalNAcV Summary The protein encoded by this gene is a Golgi type II transmembrane glycosyltransferase. The encoded protein catalyzes the transfer of sialic acid to cell surface proteins to modulate cell-cell interactions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] Expression Biased expression in lung (RPKM 3.9), brain (RPKM 3.0) and 13 other tissues See more Orthologs mouse all
ST6GALNAC6, Official Symbol ST6GALNAC6provided by HGNC Official Full Name ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6provided by HGNC Primary source HGNC:HGNC:23364 See related Ensembl:ENSG00000160408 MIM:610135; AllianceGenome:HGNC:23364 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT7F; SIAT7-F; ST6GALNACVI Summary ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in colon (RPKM 34.9), fat (RPKM 30.2) and 25 other tissues See more Orthologs mouse all
ST7, Official Symbol ST7provided by HGNC Official Full Name suppression of tumorigenicity 7provided by HGNC Primary source HGNC:HGNC:11351 See related Ensembl:ENSG00000004866 MIM:600833; AllianceGenome:HGNC:11351 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HELG; RAY1; SEN4; TSG7; ETS7q; FAM4A; FAM4A1 Summary The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 11.1), lung (RPKM 10.9) and 25 other tissues See more Orthologs mouse all
ST7-AS1, Official Symbol ST7-AS1provided by HGNC Official Full Name ST7 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:16000 See related Ensembl:ENSG00000227199 AllianceGenome:HGNC:16000 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST7AS1; ST7OT1
ST7-AS2, Official Symbol ST7-AS2provided by HGNC Official Full Name ST7 antisense RNA 2provided by HGNC Primary source HGNC:HGNC:16044 See related Ensembl:ENSG00000226367 AllianceGenome:HGNC:16044 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST7AS2; ST7OT2 Expression Low expression observed in reference dataset See more
ST7-OT3, Official Symbol ST7-OT3provided by HGNC Official Full Name ST7 overlapping transcript 3provided by HGNC Primary source HGNC:HGNC:16045 See related Ensembl:ENSG00000004866 AllianceGenome:HGNC:16045 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST7; ST7OT3; NCRNA00026 Expression Ubiquitous expression in thyroid (RPKM 6.6), lung (RPKM 6.3) and 25 other tissues See more
ST7-OT4, Official Symbol ST7-OT4provided by HGNC Official Full Name ST7 overlapping transcript 4provided by HGNC Primary source HGNC:HGNC:18835 See related Ensembl:ENSG00000214188 AllianceGenome:HGNC:18835 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST7OT4; NCRNA00042 Expression Biased expression in testis (RPKM 4.0), ovary (RPKM 0.3) and 1 other tissue See more
ST7L, Official Symbol ST7Lprovided by HGNC Official Full Name suppression of tumorigenicity 7 likeprovided by HGNC Primary source HGNC:HGNC:18441 See related Ensembl:ENSG00000007341 MIM:617640; AllianceGenome:HGNC:18441 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST7R; STLR; FAM4B Summary This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011] Expression Broad expression in testis (RPKM 6.6), skin (RPKM 3.2) and 24 other tissues See more Orthologs mouse all
ST8SIA1, Official Symbol ST8SIA1provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:10869 See related Ensembl:ENSG00000111728 MIM:601123; AllianceGenome:HGNC:10869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI Summary Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015] Expression Broad expression in brain (RPKM 1.5), adrenal (RPKM 0.7) and 19 other tissues See more Orthologs mouse all
ST8SIA2, Official Symbol ST8SIA2provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2provided by HGNC Primary source HGNC:HGNC:10870 See related Ensembl:ENSG00000140557 MIM:602546; AllianceGenome:HGNC:10870 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STX; SIAT8B; SIAT8-B; HsT19690; ST8SiaII; ST8SIA-II Summary The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 1.6), brain (RPKM 0.9) and 4 other tissues See more Orthologs mouse all
ST8SIA3, Official Symbol ST8SIA3provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3provided by HGNC Primary source HGNC:HGNC:14269 See related Ensembl:ENSG00000177511 MIM:609478; AllianceGenome:HGNC:14269 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT8C; ST8SiaIII Summary Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity and identical protein binding activity. Involved in several processes, including ganglioside biosynthetic process; glycoprotein metabolic process; and protein sialylation. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 16.9) and adrenal (RPKM 2.9) See more Orthologs mouse all
ST8SIA4, Official Symbol ST8SIA4provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4provided by HGNC Primary source HGNC:HGNC:10871 See related Ensembl:ENSG00000113532 MIM:602547; AllianceGenome:HGNC:10871 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PST; PST1; SIAT8D; SIAT8-D; ST8SiaIV; ST8SIA-IV Summary The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in appendix (RPKM 6.6), lymph node (RPKM 4.8) and 19 other tissues See more Orthologs mouse all
ST8SIA5, Official Symbol ST8SIA5provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5provided by HGNC Primary source HGNC:HGNC:17827 See related Ensembl:ENSG00000101638 MIM:607162; AllianceGenome:HGNC:17827 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIAT8E; SIAT8-E; ST8SiaV Summary The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 3.3), brain (RPKM 3.3) and 3 other tissues See more Orthologs mouse all
ST8SIA5-DT, Official Symbol ST8SIA5-DTprovided by HGNC Official Full Name ST8SIA5 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:55267 See related AllianceGenome:HGNC:55267 Gene type ncRNA RefSeq status MODEL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
ST8SIA6, Official Symbol ST8SIA6provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6provided by HGNC Primary source HGNC:HGNC:23317 See related Ensembl:ENSG00000148488 MIM:610139; AllianceGenome:HGNC:23317 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIA8F; SIAT8F; SIAT8-F; ST8SiaVI; ST8SIA-VI Summary This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] Expression Broad expression in lung (RPKM 3.3), heart (RPKM 1.0) and 14 other tissues See more Orthologs mouse all
ST8SIA6-AS1, Official Symbol ST8SIA6-AS1provided by HGNC Official Full Name ST8SIA6 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44880 See related Ensembl:ENSG00000204832 AllianceGenome:HGNC:44880 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APAL Expression Biased expression in placenta (RPKM 4.9), testis (RPKM 4.1) and 2 other tissues See more