psui3905/ncbi_genes_summary huggingface dataset:
STX2, Official Symbol STX2provided by HGNC Official Full Name syntaxin 2provided by HGNC Primary source HGNC:HGNC:3403 See related Ensembl:ENSG00000111450 MIM:132350; AllianceGenome:HGNC:3403 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPM; EPIM; STX2A; STX2B; STX2C Summary The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 4.3), lung (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
STX3, Official Symbol STX3provided by HGNC Official Full Name syntaxin 3provided by HGNC Primary source HGNC:HGNC:11438 See related Ensembl:ENSG00000166900 MIM:600876; AllianceGenome:HGNC:11438 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MVID2; STX3A; DIAR12; RDMVID Summary The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Ubiquitous expression in colon (RPKM 9.8), duodenum (RPKM 8.8) and 25 other tissues See more Orthologs mouse all
STX4, Official Symbol STX4provided by HGNC Official Full Name syntaxin 4provided by HGNC Primary source HGNC:HGNC:11439 See related Ensembl:ENSG00000103496 MIM:186591; AllianceGenome:HGNC:11439 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STX4A; p35-2 Summary Enables sphingomyelin phosphodiesterase activator activity. Involved in several processes, including cornified envelope assembly; positive regulation of immune effector process; and positive regulation of protein localization. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and lamellipodium. Part of SNARE complex. Is active in glutamatergic synapse and postsynapse. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 17.8), adrenal (RPKM 16.5) and 25 other tissues See more Orthologs mouse all
STX5, Official Symbol STX5provided by HGNC Official Full Name syntaxin 5provided by HGNC Primary source HGNC:HGNC:11440 See related Ensembl:ENSG00000162236 MIM:603189; AllianceGenome:HGNC:11440 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SED5; STX5A; CDG2AA Summary This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in thyroid (RPKM 22.3), ovary (RPKM 17.5) and 25 other tissues See more Orthologs mouse all
STX6, Official Symbol STX6provided by HGNC Official Full Name syntaxin 6provided by HGNC Primary source HGNC:HGNC:11441 See related Ensembl:ENSG00000135823 MIM:603944; AllianceGenome:HGNC:11441 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 10.0), esophagus (RPKM 7.6) and 24 other tissues See more Orthologs mouse all
STX7, Official Symbol STX7provided by HGNC Official Full Name syntaxin 7provided by HGNC Primary source HGNC:HGNC:11442 See related Ensembl:ENSG00000079950 MIM:603217; AllianceGenome:HGNC:11442 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016] Expression Ubiquitous expression in lymph node (RPKM 31.8), spleen (RPKM 19.7) and 24 other tissues See more Orthologs mouse all
STX8, Official Symbol STX8provided by HGNC Official Full Name syntaxin 8provided by HGNC Primary source HGNC:HGNC:11443 See related Ensembl:ENSG00000170310 MIM:604203; AllianceGenome:HGNC:11443 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CARB Summary The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Ubiquitous expression in testis (RPKM 14.6), fat (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
STX8P1, Official Symbol STX8P1provided by HGNC Official Full Name syntaxin 8 pseudogene 1provided by HGNC Primary source HGNC:HGNC:49855 See related AllianceGenome:HGNC:49855 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
STXBP1, Official Symbol STXBP1provided by HGNC Official Full Name syntaxin binding protein 1provided by HGNC Primary source HGNC:HGNC:11444 See related Ensembl:ENSG00000136854 MIM:602926; AllianceGenome:HGNC:11444 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P67; DEE4; NSEC1; UNC18; N-Sec1; RBSEC1; unc-18A; unc18-1; MUNC18-1 Summary This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] Expression Biased expression in brain (RPKM 151.7), adrenal (RPKM 16.3) and 6 other tissues See more Orthologs mouse all
STXBP2, Official Symbol STXBP2provided by HGNC Official Full Name syntaxin binding protein 2provided by HGNC Primary source HGNC:HGNC:11445 See related Ensembl:ENSG00000076944 MIM:601717; AllianceGenome:HGNC:11445 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FHL5; UNC18B; Hunc18b; UNC18-2; pp10122; unc-18B; MUNC18-2 Summary This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in bone marrow (RPKM 31.6), duodenum (RPKM 21.3) and 21 other tissues See more Orthologs mouse all
STXBP3, Official Symbol STXBP3provided by HGNC Official Full Name syntaxin binding protein 3provided by HGNC Primary source HGNC:HGNC:11446 See related Ensembl:ENSG00000116266 MIM:608339; AllianceGenome:HGNC:11446 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSP; MUNC18C; UNC-18C; MUNC18-3 Summary Enables syntaxin binding activity. Involved in negative regulation of calcium ion-dependent exocytosis; neutrophil degranulation; and platelet aggregation. Located in cytosol; plasma membrane; and secretory granule. Is active in presynapse. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 25.5), kidney (RPKM 20.8) and 25 other tissues See more Orthologs mouse all
STXBP4, Official Symbol STXBP4provided by HGNC Official Full Name syntaxin binding protein 4provided by HGNC Primary source HGNC:HGNC:19694 See related Ensembl:ENSG00000166263 MIM:610415; AllianceGenome:HGNC:19694 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Synip Summary Enables syntaxin binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; positive regulation of keratinocyte proliferation; and protein stabilization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 1.4), thyroid (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
STXBP5, Official Symbol STXBP5provided by HGNC Official Full Name syntaxin binding protein 5provided by HGNC Primary source HGNC:HGNC:19665 See related Ensembl:ENSG00000164506 MIM:604586; AllianceGenome:HGNC:19665 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LGL3; LLGL3; Nbla04300 Summary Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 8.9), testis (RPKM 5.6) and 25 other tissues See more Orthologs mouse all
STXBP5-AS1, Official Symbol STXBP5-AS1provided by HGNC Official Full Name STXBP5 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:44183 See related Ensembl:ENSG00000233452 AllianceGenome:HGNC:44183 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in brain (RPKM 1.3), bone marrow (RPKM 1.3) and 24 other tissues See more
STXBP5L, Official Symbol STXBP5Lprovided by HGNC Official Full Name syntaxin binding protein 5Lprovided by HGNC Primary source HGNC:HGNC:30757 See related Ensembl:ENSG00000145087 MIM:609381; AllianceGenome:HGNC:30757 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LLGL4 Summary The protein encoded by this gene is similar to syntaxin-binding protein 5 and contains ten N-terminal WD40 repeats, four variable region WD40 repeats, and a C-terminal R-SNARE domain. Studies of the orthologous proteins in mouse and rat have shown that the encoded protein may inhibit exocytosis in neurosecretory cells, and may negatively regulate the secretion of insulin. A missense variant in this gene is likely the cause of an infantile-onset neurodegenerative disorder diagnosed in two siblings of consanguineous parents. [provided by RefSeq, Jan 2017] Expression Biased expression in brain (RPKM 4.6), thyroid (RPKM 3.2) and 5 other tissues See more Orthologs mouse all
STXBP6, Official Symbol STXBP6provided by HGNC Official Full Name syntaxin binding protein 6provided by HGNC Primary source HGNC:HGNC:19666 See related Ensembl:ENSG00000168952 MIM:607958; AllianceGenome:HGNC:19666 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as amisyn; HSPC156 Summary Enables cadherin binding activity involved in cell-cell adhesion. Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Located in adherens junction. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in placenta (RPKM 6.6), brain (RPKM 5.7) and 19 other tissues See more Orthologs mouse all
STYK1, Official Symbol STYK1provided by HGNC Official Full Name serine/threonine/tyrosine kinase 1provided by HGNC Primary source HGNC:HGNC:18889 See related Ensembl:ENSG00000060140 MIM:611433; AllianceGenome:HGNC:18889 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOK; SuRTK106 Summary Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008] Expression Biased expression in colon (RPKM 5.3), stomach (RPKM 4.5) and 13 other tissues See more Orthologs mouse all
STYX, Official Symbol STYXprovided by HGNC Official Full Name serine/threonine/tyrosine interacting proteinprovided by HGNC Primary source HGNC:HGNC:11447 See related Ensembl:ENSG00000198252 MIM:615814; AllianceGenome:HGNC:11447 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in testis (RPKM 7.7), lymph node (RPKM 7.4) and 25 other tissues See more Orthologs mouse all
STYXL1, Official Symbol STYXL1provided by HGNC Official Full Name serine/threonine/tyrosine interacting like 1provided by HGNC Primary source HGNC:HGNC:18165 See related Ensembl:ENSG00000127952 MIM:616695; AllianceGenome:HGNC:18165 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUSP24; MKSTYX; MK-STYX Summary Enables protein phosphatase binding activity; protein phosphatase inhibitor activity; and pseudophosphatase activity. Involved in several processes, including negative regulation of phosphoprotein phosphatase activity; negative regulation of stress granule assembly; and positive regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 9.4), esophagus (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
STYXL2, Official Symbol STYXL2provided by HGNC Official Full Name serine/threonine/tyrosine interacting like 2provided by HGNC Primary source HGNC:HGNC:25034 See related Ensembl:ENSG00000198842 AllianceGenome:HGNC:25034 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUSP27 Summary Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in sarcomere. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in heart (RPKM 26.2) and prostate (RPKM 2.1) See more Orthologs mouse all
SUB1, Official Symbol SUB1provided by HGNC Official Full Name SUB1 regulator of transcriptionprovided by HGNC Primary source HGNC:HGNC:19985 See related Ensembl:ENSG00000113387 MIM:600503; AllianceGenome:HGNC:19985 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P15; PC4; p14 Summary Enables identical protein binding activity; single-stranded DNA binding activity; and transcription coactivator activity. Involved in negative regulation of DNA metabolic process and regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 41.5), fat (RPKM 34.4) and 25 other tissues See more Orthologs mouse all
SUB1P3, Official Symbol SUB1P3provided by HGNC Official Full Name SUB1 pseudogene 3provided by HGNC Primary source HGNC:HGNC:43993 See related AllianceGenome:HGNC:43993 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUB1P4, Official Symbol SUB1P4provided by HGNC Official Full Name SUB1 pseudogene 4provided by HGNC Primary source HGNC:HGNC:43994 See related AllianceGenome:HGNC:43994 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUCLA2, Official Symbol SUCLA2provided by HGNC Official Full Name succinate-CoA ligase ADP-forming subunit betaprovided by HGNC Primary source HGNC:HGNC:11448 See related Ensembl:ENSG00000136143 MIM:603921; AllianceGenome:HGNC:11448 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A-SCS; A-BETA; MTDPS5; LINC00444; SCS-betaA Summary Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 24.1), fat (RPKM 23.0) and 25 other tissues See more Orthologs mouse all
SUCLA2-AS1, Official Symbol SUCLA2-AS1provided by HGNC Official Full Name SUCLA2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:39965 See related AllianceGenome:HGNC:39965 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
SUCLA2P2, Official Symbol SUCLA2P2provided by HGNC Official Full Name SUCLA2 pseudogene 2provided by HGNC Primary source HGNC:HGNC:38102 See related Ensembl:ENSG00000233107 AllianceGenome:HGNC:38102 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUCLG1, Official Symbol SUCLG1provided by HGNC Official Full Name succinate-CoA ligase GDP/ADP-forming subunit alphaprovided by HGNC Primary source HGNC:HGNC:11449 See related Ensembl:ENSG00000163541 MIM:611224; AllianceGenome:HGNC:11449 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GALPHA; MTDPS9; SUCLA1 Summary This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010] Expression Broad expression in kidney (RPKM 188.3), duodenum (RPKM 98.6) and 25 other tissues See more Orthologs mouse all
SUCLG2, Official Symbol SUCLG2provided by HGNC Official Full Name succinate-CoA ligase GDP-forming subunit betaprovided by HGNC Primary source HGNC:HGNC:11450 See related Ensembl:ENSG00000172340 MIM:603922; AllianceGenome:HGNC:11450 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G-SCS; GBETA; GTPSCS Summary This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. [provided by RefSeq, Apr 2010] Expression Ubiquitous expression in colon (RPKM 21.2), kidney (RPKM 16.3) and 25 other tissues See more Orthologs mouse all
SUCLG2P4, Official Symbol SUCLG2P4provided by HGNC Official Full Name SUCLG2 pseudogene 4provided by HGNC Primary source HGNC:HGNC:43999 See related AllianceGenome:HGNC:43999 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUCNR1, Official Symbol SUCNR1provided by HGNC Official Full Name succinate receptor 1provided by HGNC Primary source HGNC:HGNC:4542 See related Ensembl:ENSG00000198829 MIM:606381; AllianceGenome:HGNC:4542 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPR91 Summary This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009] Expression Biased expression in kidney (RPKM 20.6), thyroid (RPKM 7.3) and 7 other tissues See more Orthologs mouse all
SUCO, Official Symbol SUCOprovided by HGNC Official Full Name SUN domain containing ossification factorprovided by HGNC Primary source HGNC:HGNC:1240 See related Ensembl:ENSG00000094975 MIM:619434; AllianceGenome:HGNC:1240 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CH1; OPT; SLP1; C1orf9 Summary Predicted to be involved in positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; and regulation of bone remodeling. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 30.3), testis (RPKM 17.2) and 25 other tissues See more Orthologs mouse all
SUDS3, Official Symbol SUDS3provided by HGNC Official Full Name SDS3 homolog, SIN3A corepressor complex componentprovided by HGNC Primary source HGNC:HGNC:29545 See related Ensembl:ENSG00000111707 MIM:608250; AllianceGenome:HGNC:29545 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SDS3; SAP45 Summary SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in thyroid (RPKM 8.3), testis (RPKM 7.0) and 25 other tissues See more Orthologs mouse all
SUFU, Official Symbol SUFUprovided by HGNC Official Full Name SUFU negative regulator of hedgehog signalingprovided by HGNC Primary source HGNC:HGNC:16466 See related Ensembl:ENSG00000107882 MIM:607035; AllianceGenome:HGNC:16466 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCNS2; SUFUH; JBTS32; SUFUXL; PRO1280 Summary The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Expression Ubiquitous expression in skin (RPKM 4.8), ovary (RPKM 4.2) and 25 other tissues See more Orthologs mouse all
SUGCT, Official Symbol SUGCTprovided by HGNC Official Full Name succinyl-CoA:glutarate-CoA transferaseprovided by HGNC Primary source HGNC:HGNC:16001 See related Ensembl:ENSG00000175600 MIM:609187; AllianceGenome:HGNC:16001 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GA3; ORF19; DERP13; C7orf10 Summary This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] Expression Biased expression in kidney (RPKM 3.4), liver (RPKM 1.2) and 12 other tissues See more Orthologs mouse all
SUGCT-AS1, Official Symbol SUGCT-AS1provided by HGNC Official Full Name SUGCT antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40745 See related Ensembl:ENSG00000203446 AllianceGenome:HGNC:40745 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
SUGP1, Official Symbol SUGP1provided by HGNC Official Full Name SURP and G-patch domain containing 1provided by HGNC Primary source HGNC:HGNC:18643 See related Ensembl:ENSG00000105705 MIM:607992; AllianceGenome:HGNC:18643 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RBP; SF4; F23858 Summary SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003] Expression Ubiquitous expression in testis (RPKM 17.9), spleen (RPKM 9.9) and 25 other tissues See more Orthologs mouse all
SUGP2, Official Symbol SUGP2provided by HGNC Official Full Name SURP and G-patch domain containing 2provided by HGNC Primary source HGNC:HGNC:18641 See related Ensembl:ENSG00000064607 MIM:607993; AllianceGenome:HGNC:18641 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SFRS14; SRFS14 Summary This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009] Expression Broad expression in testis (RPKM 45.5), brain (RPKM 19.3) and 24 other tissues See more Orthologs mouse all
SUGT1, Official Symbol SUGT1provided by HGNC Official Full Name SGT1 homolog, MIS12 kinetochore complex assembly cochaperoneprovided by HGNC Primary source HGNC:HGNC:16987 See related Ensembl:ENSG00000165416 MIM:604098; AllianceGenome:HGNC:16987 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SGT1 Summary This gene encodes a highly conserved nuclear protein involved in kinetochore function and required for the G1/S and G2/M transitions. This protein interacts with heat shock protein 90. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene have been defined on several different chromosomes. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in brain (RPKM 4.1), testis (RPKM 3.2) and 25 other tissues See more Orthologs mouse all
SUGT1-DT, Official Symbol SUGT1-DTprovided by HGNC Official Full Name SUGT1 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:54809 See related Ensembl:ENSG00000273723 AllianceGenome:HGNC:54809 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUGT1P1, Official Symbol SUGT1P1provided by HGNC Official Full Name SUGT1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:19384 See related AllianceGenome:HGNC:19384 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SGT1P; SUGT1P; bA255A11.1 Expression Biased expression in testis (RPKM 6.1), brain (RPKM 1.2) and 12 other tissues See more
SUGT1P2, Official Symbol SUGT1P2provided by HGNC Official Full Name SUGT1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:31377 See related Ensembl:ENSG00000213842 AllianceGenome:HGNC:31377 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUGT1P4, Official Symbol SUGT1P4provided by HGNC Official Full Name SUGT1 pseudogene 4provided by HGNC Primary source HGNC:HGNC:53832 See related AllianceGenome:HGNC:53832 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SUGT1P4-STRA6LP-CCDC180, Official Symbol SUGT1P4-STRA6LP-CCDC180provided by HGNC Official Full Name SUGT1P4-STRA6LP-CCDC180 readthroughprovided by HGNC Primary source HGNC:HGNC:53835 See related Ensembl:ENSG00000255036 AllianceGenome:HGNC:53835 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LOC100499484-C9ORF174 Summary This locus represents a set of read-through transcripts spanning an upstream pseudogene (GeneID:100499484) extending into a downstream protein-coding locus (GeneID:100499483). All of the read-through transcripts are candidates for nonsense-mediated decay (NMD), so they are not thought to express a protein. [provided by RefSeq, Aug 2010] Expression Biased expression in testis (RPKM 13.8), lung (RPKM 2.2) and 11 other tissues See more
SULF1, Official Symbol SULF1provided by HGNC Official Full Name sulfatase 1provided by HGNC Primary source HGNC:HGNC:20391 See related Ensembl:ENSG00000137573 MIM:610012; AllianceGenome:HGNC:20391 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SULF-1 Summary This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Broad expression in urinary bladder (RPKM 23.6), prostate (RPKM 21.2) and 19 other tissues See more Orthologs mouse all
SULF2, Official Symbol SULF2provided by HGNC Official Full Name sulfatase 2provided by HGNC Primary source HGNC:HGNC:20392 See related Ensembl:ENSG00000196562 MIM:610013; AllianceGenome:HGNC:20392 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSULF-2 Summary Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in ovary (RPKM 36.9), endometrium (RPKM 36.6) and 24 other tissues See more Orthologs mouse all
SULT1A1, Official Symbol SULT1A1provided by HGNC Official Full Name sulfotransferase family 1A member 1provided by HGNC Primary source HGNC:HGNC:11453 See related Ensembl:ENSG00000196502 MIM:171150; AllianceGenome:HGNC:11453 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PST; STP; STP1; P-PST; ST1A1; ST1A3; TSPST1; ts-PST; P-PST 1; HAST1/HAST2 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in duodenum (RPKM 44.2), liver (RPKM 36.4) and 22 other tissues See more Orthologs mouse all
SULT1A2, Official Symbol SULT1A2provided by HGNC Official Full Name sulfotransferase family 1A member 2provided by HGNC Primary source HGNC:HGNC:11454 See related Ensembl:ENSG00000197165 MIM:601292; AllianceGenome:HGNC:11454 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STP2; HAST4; P-PST; ST1A2; TSPST2; P-PST 2 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in duodenum (RPKM 25.0), small intestine (RPKM 22.6) and 13 other tissues See more Orthologs all
SULT1A3, Official Symbol SULT1A3provided by HGNC Official Full Name sulfotransferase family 1A member 3provided by HGNC Primary source HGNC:HGNC:11455 See related Ensembl:ENSG00000261052 MIM:600641; AllianceGenome:HGNC:11455 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STM; HAST; HAST3; M-PST; ST1A3; ST1A4; ST1A5; TL-PST; ST1A3/ST1A4 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010] Expression Broad expression in duodenum (RPKM 134.6), small intestine (RPKM 93.8) and 23 other tissues See more Orthologs all
SULT1A4, Official Symbol SULT1A4provided by HGNC Official Full Name sulfotransferase family 1A member 4provided by HGNC Primary source HGNC:HGNC:30004 See related Ensembl:ENSG00000213648 MIM:615819; AllianceGenome:HGNC:30004 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STM; HAST3; M-PST; ST1A3; ST1A4; TL-PST; ST1A3/ST1A4 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16, this gene and SULT1A3 arose from a segmental duplication. Read-through transcription exists between this gene and the upstream SLX1B (SLX1 structure-specific endonuclease subunit homolog B) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010] Expression Broad expression in duodenum (RPKM 135.4), small intestine (RPKM 94.3) and 23 other tissues See more Orthologs all
SULT1B1, Official Symbol SULT1B1provided by HGNC Official Full Name sulfotransferase family 1B member 1provided by HGNC Primary source HGNC:HGNC:17845 See related Ensembl:ENSG00000173597 MIM:608436; AllianceGenome:HGNC:17845 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST1B1; ST1B2; SULT1B2 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008] Expression Biased expression in duodenum (RPKM 43.3), small intestine (RPKM 41.2) and 5 other tissues See more Orthologs mouse all
SULT1C2, Official Symbol SULT1C2provided by HGNC Official Full Name sulfotransferase family 1C member 2provided by HGNC Primary source HGNC:HGNC:11456 See related Ensembl:ENSG00000198203 MIM:602385; AllianceGenome:HGNC:11456 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST1C1; ST1C2; SULT1C1; humSULTC2 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in stomach (RPKM 61.8), kidney (RPKM 26.2) and 3 other tissues See more Orthologs all
SULT1C2P2, Official Symbol SULT1C2P2provided by HGNC Official Full Name sulfotransferase family, cytosolic, 1C, member 2 pseudogene 2provided by HGNC Primary source HGNC:HGNC:51595 See related Ensembl:ENSG00000261209 AllianceGenome:HGNC:51595 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
SULT1C3, Official Symbol SULT1C3provided by HGNC Official Full Name sulfotransferase family 1C member 3provided by HGNC Primary source HGNC:HGNC:33543 See related Ensembl:ENSG00000196228 MIM:617151; AllianceGenome:HGNC:33543 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST1C3 Summary Enables 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Involved in 3'-phosphoadenosine 5'-phosphosulfate metabolic process; cholesterol metabolic process; and xenobiotic metabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
SULT1C4, Official Symbol SULT1C4provided by HGNC Official Full Name sulfotransferase family 1C member 4provided by HGNC Primary source HGNC:HGNC:11457 See related Ensembl:ENSG00000198075 MIM:608357; AllianceGenome:HGNC:11457 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SULT1C; SULT1C2 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008] Expression Broad expression in gall bladder (RPKM 13.7), ovary (RPKM 9.3) and 15 other tissues See more Orthologs all
SULT1D1P, Official Symbol SULT1D1Pprovided by HGNC Official Full Name sulfotransferase family 1D member 1, pseudogeneprovided by HGNC Primary source HGNC:HGNC:30659 See related Ensembl:ENSG00000236959 AllianceGenome:HGNC:30659 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SULT1D1 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. This gene has been inactivated by mutation and is nonfunctional in humans. [provided by RefSeq, Oct 2008]