psui3905/ncbi_genes_summary huggingface dataset:
MORC3, Official Symbol MORC3provided by HGNC Official Full Name MORC family CW-type zinc finger 3provided by HGNC Primary source HGNC:HGNC:23572 See related Ensembl:ENSG00000159256 MIM:610078; AllianceGenome:HGNC:23572 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NXP2; ZCW5; ZCWCC3 Summary This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in bone marrow (RPKM 15.2), ovary (RPKM 12.6) and 25 other tissues See more Orthologs mouse all
MORC4, Official Symbol MORC4provided by HGNC Official Full Name MORC family CW-type zinc finger 4provided by HGNC Primary source HGNC:HGNC:23485 See related Ensembl:ENSG00000133131 MIM:300970; AllianceGenome:HGNC:23485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZCW4; ZCWCC2; dJ75H8.2 Summary In human, the four current members of the microrchidia (morc) gene family share an N-terminal ATPase-like ATP-binding region and a CW four-cysteine zinc-finger motif. The protein encoded by this gene also has a nuclear matrix binding domain and a two-stranded coiled-coil motif near its C-terminus. This gene is widely expressed at low levels in normal tissues and has elevated expression in placenta and testis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010] Expression Broad expression in placenta (RPKM 38.5), adrenal (RPKM 15.2) and 18 other tissues See more Orthologs mouse all
MORF4, Official Symbol MORF4provided by HGNC Official Full Name mortality factor 4 (pseudogene)provided by HGNC Primary source HGNC:HGNC:15773 See related MIM:116960; AllianceGenome:HGNC:15773 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSR; SEN; CSRB; SEN1 Summary Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM, Apr 2004]
MORF4L1, Official Symbol MORF4L1provided by HGNC Official Full Name mortality factor 4 like 1provided by HGNC Primary source HGNC:HGNC:16989 See related Ensembl:ENSG00000185787 MIM:607303; AllianceGenome:HGNC:16989 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15 Summary Enables protein N-terminus binding activity. Involved in double-strand break repair via homologous recombination and histone modification. Located in nuclear speck. Part of NuA4 histone acetyltransferase complex and Sin3 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 192.5), brain (RPKM 119.7) and 25 other tissues See more Orthologs mouse all
MORF4L1P3, Official Symbol MORF4L1P3provided by HGNC Official Full Name mortality factor 4 like 1 pseudogene 3provided by HGNC Primary source HGNC:HGNC:20402 See related AllianceGenome:HGNC:20402 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRG11; MORF4LP3
MORF4L1P4, Official Symbol MORF4L1P4provided by HGNC Official Full Name mortality factor 4 like 1 pseudogene 4provided by HGNC Primary source HGNC:HGNC:39257 See related Ensembl:ENSG00000225133 AllianceGenome:HGNC:39257 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MORF4L1P5, Official Symbol MORF4L1P5provided by HGNC Official Full Name mortality factor 4 like 1 pseudogene 5provided by HGNC Primary source HGNC:HGNC:35425 See related Ensembl:ENSG00000231857 AllianceGenome:HGNC:35425 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MORF4LP5
MORF4L1P7, Official Symbol MORF4L1P7provided by HGNC Official Full Name mortality factor 4 like 1 pseudogene 7provided by HGNC Primary source HGNC:HGNC:39259 See related AllianceGenome:HGNC:39259 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MORF4L2, Official Symbol MORF4L2provided by HGNC Official Full Name mortality factor 4 like 2provided by HGNC Primary source HGNC:HGNC:16849 See related Ensembl:ENSG00000123562 MIM:300409; AllianceGenome:HGNC:16849 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRGX; MORFL2 Summary Predicted to be involved in heterochromatin assembly and histone modification. Predicted to act upstream of or within positive regulation of striated muscle cell differentiation and positive regulation of transcription by RNA polymerase II. Located in nucleolus; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 110.4), endometrium (RPKM 100.8) and 25 other tissues See more Orthologs mouse all
MORF4L2-AS1, Official Symbol MORF4L2-AS1provided by HGNC Official Full Name MORF4L2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:27991 See related AllianceGenome:HGNC:27991 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in ovary (RPKM 2.3), endometrium (RPKM 1.7) and 24 other tissues See more
MORN1, Official Symbol MORN1provided by HGNC Official Full Name MORN repeat containing 1provided by HGNC Primary source HGNC:HGNC:25852 See related Ensembl:ENSG00000116151 AllianceGenome:HGNC:25852 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in testis (RPKM 1.1), ovary (RPKM 0.8) and 25 other tissues See more Orthologs mouse all
MORN2, Official Symbol MORN2provided by HGNC Official Full Name MORN repeat containing 2provided by HGNC Primary source HGNC:HGNC:30166 See related Ensembl:ENSG00000188010 AllianceGenome:HGNC:30166 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOPT; BLOCK27 Summary Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in acrosomal vesicle and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 66.4), kidney (RPKM 22.6) and 16 other tissues See more Orthologs mouse all
MORN3, Official Symbol MORN3provided by HGNC Official Full Name MORN repeat containing 3provided by HGNC Primary source HGNC:HGNC:29807 See related Ensembl:ENSG00000139714 AllianceGenome:HGNC:29807 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 17.3), brain (RPKM 1.3) and 3 other tissues See more Orthologs mouse all
MORN4, Official Symbol MORN4provided by HGNC Official Full Name MORN repeat containing 4provided by HGNC Primary source HGNC:HGNC:24001 See related Ensembl:ENSG00000171160 MIM:617736; AllianceGenome:HGNC:24001 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UTA; rtp; C10orf83; bA548K23.4 Summary Predicted to be involved in response to axon injury. Located in cytoplasm and filopodium tip. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 7.3), kidney (RPKM 3.8) and 23 other tissues See more Orthologs mouse all
MORN5, Official Symbol MORN5provided by HGNC Official Full Name MORN repeat containing 5provided by HGNC Primary source HGNC:HGNC:17841 See related Ensembl:ENSG00000185681 MIM:619837; AllianceGenome:HGNC:17841 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C9orf18; C9orf113 Expression Broad expression in testis (RPKM 7.1), heart (RPKM 2.0) and 21 other tissues See more Orthologs mouse all
MOS, Official Symbol MOSprovided by HGNC Official Full Name MOS proto-oncogene, serine/threonine kinaseprovided by HGNC Primary source HGNC:HGNC:7199 See related Ensembl:ENSG00000172680 MIM:190060; AllianceGenome:HGNC:7199 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MSV; OZEMA20 Summary MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009] Orthologs mouse all
MOSMO, Official Symbol MOSMOprovided by HGNC Official Full Name modulator of smoothenedprovided by HGNC Primary source HGNC:HGNC:27087 See related Ensembl:ENSG00000185716 AllianceGenome:HGNC:27087 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATTHOG; BC030336; C16orf52 Summary Predicted to be involved in negative regulation of smoothened signaling pathway; regulation of neuron differentiation; and regulation of protein stability. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 11.6), brain (RPKM 8.9) and 24 other tissues See more Orthologs mouse all
MOSPD1, Official Symbol MOSPD1provided by HGNC Official Full Name motile sperm domain containing 1provided by HGNC Primary source HGNC:HGNC:25235 See related Ensembl:ENSG00000101928 MIM:300674; AllianceGenome:HGNC:25235 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DJ473B4 Summary Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 7.2), adrenal (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
MOSPD2, Official Symbol MOSPD2provided by HGNC Official Full Name motile sperm domain containing 2provided by HGNC Primary source HGNC:HGNC:28381 See related Ensembl:ENSG00000130150 MIM:301086; AllianceGenome:HGNC:28381 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Involved in positive regulation of monocyte chemotaxis and positive regulation of neutrophil chemotaxis. Located in endoplasmic reticulum and endoplasmic reticulum-endosome membrane contact site. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 8.4), brain (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
MOSPD3, Official Symbol MOSPD3provided by HGNC Official Full Name motile sperm domain containing 3provided by HGNC Primary source HGNC:HGNC:25078 See related Ensembl:ENSG00000106330 MIM:609125; AllianceGenome:HGNC:25078 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDS3; NET30 Summary This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 10.0), adrenal (RPKM 6.8) and 25 other tissues See more Orthologs mouse all
MOV10, Official Symbol MOV10provided by HGNC Official Full Name Mov10 RISC complex RNA helicaseprovided by HGNC Primary source HGNC:HGNC:7200 See related Ensembl:ENSG00000155363 MIM:610742; AllianceGenome:HGNC:7200 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as gb110; fSAP113 Summary Enables 5'-3' RNA helicase activity and RNA binding activity. Involved in defense response to virus; negative regulation of transposition, RNA-mediated; and posttranscriptional regulation of gene expression. Located in P-body and cytosol. Implicated in hypertension. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 19.5), small intestine (RPKM 18.6) and 25 other tissues See more Orthologs mouse all
MOV10L1, Official Symbol MOV10L1provided by HGNC Official Full Name Mov10 like RISC complex RNA helicase 1provided by HGNC Primary source HGNC:HGNC:7201 See related Ensembl:ENSG00000073146 MIM:605794; AllianceGenome:HGNC:7201 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHAMP; SPGF73; DJ402G11.8 Summary This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] Expression Restricted expression toward testis (RPKM 7.8) See more Orthologs mouse all
MOXD1, Official Symbol MOXD1provided by HGNC Official Full Name monooxygenase DBH like 1provided by HGNC Primary source HGNC:HGNC:21063 See related Ensembl:ENSG00000079931 MIM:609000; AllianceGenome:HGNC:21063 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOX; PRO5780; dJ248E1.1 Summary Predicted to enable copper ion binding activity and dopamine beta-monooxygenase activity. Predicted to be involved in dopamine catabolic process; norepinephrine biosynthetic process; and octopamine biosynthetic process. Part of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 34.3), adrenal (RPKM 21.6) and 17 other tissues See more Orthologs mouse all
MOXD2P, Official Symbol MOXD2Pprovided by HGNC Official Full Name monooxygenase DBH like 2, pseudogeneprovided by HGNC Primary source HGNC:HGNC:33605 See related Ensembl:ENSG00000240268 AllianceGenome:HGNC:33605 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOXD2 Summary Predicted to enable copper ion binding activity and dopamine beta-monooxygenase activity. Predicted to be involved in dopamine catabolic process; norepinephrine biosynthetic process; and octopamine biosynthetic process. Predicted to be active in extracellular space and secretory granule membrane. [provided by Alliance of Genome Resources, Apr 2022]
MPC1, Official Symbol MPC1provided by HGNC Official Full Name mitochondrial pyruvate carrier 1provided by HGNC Primary source HGNC:HGNC:21606 See related Ensembl:ENSG00000060762 MIM:614738; AllianceGenome:HGNC:21606 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPYCD; BRP44L; CGI-129; SLC54A1 Summary The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012] Expression Broad expression in heart (RPKM 92.1), kidney (RPKM 35.4) and 23 other tissues See more Orthologs mouse all
MPC1L, Official Symbol MPC1Lprovided by HGNC Official Full Name mitochondrial pyruvate carrier 1 likeprovided by HGNC Primary source HGNC:HGNC:44205 See related Ensembl:ENSG00000238205 MIM:301103; AllianceGenome:HGNC:44205 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLC54A3 Summary Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
MPC2, Official Symbol MPC2provided by HGNC Official Full Name mitochondrial pyruvate carrier 2provided by HGNC Primary source HGNC:HGNC:24515 See related Ensembl:ENSG00000143158 MIM:614737; AllianceGenome:HGNC:24515 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BRP44; SLC54A2 Summary Enables identical protein binding activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 34.8), liver (RPKM 32.8) and 25 other tissues See more Orthologs mouse all
MPDU1, Official Symbol MPDU1provided by HGNC Official Full Name mannose-P-dolichol utilization defect 1provided by HGNC Primary source HGNC:HGNC:7207 See related Ensembl:ENSG00000129255 MIM:604041; AllianceGenome:HGNC:7207 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SL15; CDGIF; Lec35; My008; PQLC5; PP3958; SLC66A5; HBEBP2BPA Summary This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] Expression Ubiquitous expression in colon (RPKM 20.5), duodenum (RPKM 20.5) and 25 other tissues See more Orthologs mouse all
MPDZ, Official Symbol MPDZprovided by HGNC Official Full Name multiple PDZ domain crumbs cell polarity complex componentprovided by HGNC Primary source HGNC:HGNC:7208 See related Ensembl:ENSG00000107186 MIM:603785; AllianceGenome:HGNC:7208 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYC2; MUPP1 Summary The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in liver (RPKM 12.7), fat (RPKM 10.5) and 23 other tissues See more Orthologs mouse all
MPEG1, Official Symbol MPEG1provided by HGNC Official Full Name macrophage expressed 1provided by HGNC Primary source HGNC:HGNC:29619 See related Ensembl:ENSG00000197629 MIM:610390; AllianceGenome:HGNC:29619 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P-2; MPG1; MPS1; IMD77; Mpg-1 Summary Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in cytoplasmic vesicle. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
MPG, Official Symbol MPGprovided by HGNC Official Full Name N-methylpurine DNA glycosylaseprovided by HGNC Primary source HGNC:HGNC:7211 See related Ensembl:ENSG00000103152 MIM:156565; AllianceGenome:HGNC:7211 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAG; MDG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1 Summary Predicted to enable alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 19.8), spleen (RPKM 17.9) and 25 other tissues See more Orthologs mouse all
MPHOSPH10, Official Symbol MPHOSPH10provided by HGNC Official Full Name M-phase phosphoprotein 10provided by HGNC Primary source HGNC:HGNC:7213 See related Ensembl:ENSG00000124383 MIM:605503; AllianceGenome:HGNC:7213 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT90; MPP10; MPP10P; PPP1R106 Summary This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in esophagus (RPKM 13.3), prostate (RPKM 12.5) and 25 other tissues See more Orthologs mouse all
MPHOSPH6, Official Symbol MPHOSPH6provided by HGNC Official Full Name M-phase phosphoprotein 6provided by HGNC Primary source HGNC:HGNC:7214 See related Ensembl:ENSG00000135698 MIM:605500; AllianceGenome:HGNC:7214 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPP; MPP6; MPP-6 Summary Predicted to enable RNA binding activity. Involved in maturation of 5.8S rRNA. Located in cytosol; nucleolus; and nucleoplasm. Colocalizes with nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 8.9), urinary bladder (RPKM 8.6) and 24 other tissues See more Orthologs mouse all
MPHOSPH6-DT, Official Symbol MPHOSPH6-DTprovided by HGNC Official Full Name MPHOSPH6 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:55377 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
MPHOSPH8, Official Symbol MPHOSPH8provided by HGNC Official Full Name M-phase phosphoprotein 8provided by HGNC Primary source HGNC:HGNC:29810 See related Ensembl:ENSG00000196199 MIM:611626; AllianceGenome:HGNC:29810 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TWA3; mpp8; HSMPP8 Summary Enables chromatin binding activity and methylated histone binding activity. Involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; regulation of DNA methylation; and regulation of gene expression. Located in several cellular components, including cytosol; heterochromatin; and nuclear lumen. Part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 20.0), spleen (RPKM 15.8) and 25 other tissues See more Orthologs mouse all
MPHOSPH9, Official Symbol MPHOSPH9provided by HGNC Official Full Name M-phase phosphoprotein 9provided by HGNC Primary source HGNC:HGNC:7215 See related Ensembl:ENSG00000051825 MIM:605501; AllianceGenome:HGNC:7215 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPP9; MPP-9 Summary Located in Golgi apparatus and centriole. Implicated in multiple sclerosis. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 6.2), testis (RPKM 5.8) and 24 other tissues See more Orthologs mouse all
MPI, Official Symbol MPIprovided by HGNC Official Full Name mannose phosphate isomeraseprovided by HGNC Primary source HGNC:HGNC:7216 See related Ensembl:ENSG00000178802 MIM:154550; AllianceGenome:HGNC:7216 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PMI; PMI1; CDG1B Summary Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Expression Ubiquitous expression in duodenum (RPKM 9.9), small intestine (RPKM 9.3) and 25 other tissues See more Orthologs mouse all
MPIG6B, Official Symbol MPIG6Bprovided by HGNC Official Full Name megakaryocyte and platelet inhibitory receptor G6bprovided by HGNC Primary source HGNC:HGNC:13937 See related Ensembl:ENSG00000204420 MIM:606520; AllianceGenome:HGNC:13937 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G6b; NG31; G6b-B; THAMY; C6orf25 Summary This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in skin (RPKM 2.2), bone marrow (RPKM 1.5) and 14 other tissues See more Orthologs mouse all
MPL, Official Symbol MPLprovided by HGNC Official Full Name MPL proto-oncogene, thrombopoietin receptorprovided by HGNC Primary source HGNC:HGNC:7217 See related Ensembl:ENSG00000117400 MIM:159530; AllianceGenome:HGNC:7217 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPLV; TPOR; C-MPL; CD110; THPOR; THCYT2 Summary In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
MPLKIP, Official Symbol MPLKIPprovided by HGNC Official Full Name M-phase specific PLK1 interacting proteinprovided by HGNC Primary source HGNC:HGNC:16002 See related Ensembl:ENSG00000168303 MIM:609188; AllianceGenome:HGNC:16002 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABHS; TTD4; ORF20; C7orf11 Summary The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy. [provided by RefSeq, Nov 2009] Expression Ubiquitous expression in liver (RPKM 18.5), kidney (RPKM 17.4) and 25 other tissues See more Orthologs mouse all
MPND, Official Symbol MPNDprovided by HGNC Official Full Name MPN domain containingprovided by HGNC Primary source HGNC:HGNC:25934 See related Ensembl:ENSG00000008382 AllianceGenome:HGNC:25934 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable histone binding activity; peptidase activity; and transcription coactivator activity. Predicted to be involved in chromatin remodeling and positive regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 12.4), duodenum (RPKM 11.4) and 25 other tissues See more Orthologs mouse all
MPO, Official Symbol MPOprovided by HGNC Official Full Name myeloperoxidaseprovided by HGNC Primary source HGNC:HGNC:7218 See related Ensembl:ENSG00000005381 MIM:606989; AllianceGenome:HGNC:7218 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] Expression Restricted expression toward bone marrow (RPKM 1596.3) See more Orthologs mouse all
MPP1, Official Symbol MPP1provided by HGNC Official Full Name MAGUK p55 scaffold protein 1provided by HGNC Primary source HGNC:HGNC:7219 See related Ensembl:ENSG00000130830 MIM:305360; AllianceGenome:HGNC:7219 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRG1; PEMP; AAG12; EMP55; DXS552E Summary This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Expression Broad expression in placenta (RPKM 52.9), bone marrow (RPKM 48.1) and 25 other tissues See more Orthologs mouse all
MPP2, Official Symbol MPP2provided by HGNC Official Full Name MAGUK p55 scaffold protein 2provided by HGNC Primary source HGNC:HGNC:7220 See related Ensembl:ENSG00000108852 MIM:600723; AllianceGenome:HGNC:7220 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DLG2 Summary Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 9.3), testis (RPKM 5.8) and 12 other tissues See more Orthologs mouse all
MPP3, Official Symbol MPP3provided by HGNC Official Full Name MAGUK p55 scaffold protein 3provided by HGNC Primary source HGNC:HGNC:7221 See related Ensembl:ENSG00000161647 MIM:601114; AllianceGenome:HGNC:7221 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DLG3 Summary This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 3.1), lung (RPKM 2.5) and 23 other tissues See more Orthologs mouse all
MPP4, Official Symbol MPP4provided by HGNC Official Full Name MAGUK p55 scaffold protein 4provided by HGNC Primary source HGNC:HGNC:13680 See related Ensembl:ENSG00000082126 MIM:606575; AllianceGenome:HGNC:13680 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DLG6; ALS2CR5 Summary This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
MPP7, Official Symbol MPP7provided by HGNC Official Full Name MAGUK p55 scaffold protein 7provided by HGNC Primary source HGNC:HGNC:26542 See related Ensembl:ENSG00000150054 MIM:610973; AllianceGenome:HGNC:26542 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in esophagus (RPKM 17.1), skin (RPKM 11.1) and 24 other tissues See more Orthologs mouse all
MPPE1, Official Symbol MPPE1provided by HGNC Official Full Name metallophosphoesterase 1provided by HGNC Primary source HGNC:HGNC:15988 See related Ensembl:ENSG00000154889 MIM:611900; AllianceGenome:HGNC:15988 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Cdc1; PGAP5 Summary Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Involved in GPI anchor biosynthetic process. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 13.2), prostate (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
MPPE1P1, Official Symbol MPPE1P1provided by HGNC Official Full Name metallophosphoesterase 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:20143 See related AllianceGenome:HGNC:20143 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPPE1P
MPPED1, Official Symbol MPPED1provided by HGNC Official Full Name metallophosphoesterase domain containing 1provided by HGNC Primary source HGNC:HGNC:1306 See related Ensembl:ENSG00000186732 MIM:602112; AllianceGenome:HGNC:1306 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 239AB; FAM1A; C22orf1 Summary Predicted to enable hydrolase activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 6.2) and liver (RPKM 1.2) See more Orthologs mouse all
MPPED2, Official Symbol MPPED2provided by HGNC Official Full Name metallophosphoesterase domain containing 2provided by HGNC Primary source HGNC:HGNC:1180 See related Ensembl:ENSG00000066382 MIM:600911; AllianceGenome:HGNC:1180 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 239FB; C11orf8 Summary Predicted to enable manganese ion binding activity; phosphoric diester hydrolase activity; and purine ribonucleotide binding activity. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in thyroid (RPKM 4.7), prostate (RPKM 2.5) and 11 other tissues See more Orthologs mouse all
MPPED2-AS1, Official Symbol MPPED2-AS1provided by HGNC Official Full Name MPPED2 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:53909 See related Ensembl:ENSG00000254489 AllianceGenome:HGNC:53909 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
MPRIP, Official Symbol MPRIPprovided by HGNC Official Full Name myosin phosphatase Rho interacting proteinprovided by HGNC Primary source HGNC:HGNC:30321 See related Ensembl:ENSG00000133030 MIM:612935; AllianceGenome:HGNC:30321 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRIP; RIP3; M-RIP; RHOIP3; p116Rip Summary Enables cadherin binding activity. Predicted to be involved in actin filament organization. Located in actin cytoskeleton and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in endometrium (RPKM 19.8), brain (RPKM 18.4) and 25 other tissues See more Orthologs mouse all
MPRIP-AS1, Official Symbol MPRIP-AS1provided by HGNC Official Full Name MPRIP antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41263 See related AllianceGenome:HGNC:41263 Gene type ncRNA Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Annotation information not in current annotation release
MPST, Official Symbol MPSTprovided by HGNC Official Full Name mercaptopyruvate sulfurtransferaseprovided by HGNC Primary source HGNC:HGNC:7223 See related Ensembl:ENSG00000128309 MIM:602496; AllianceGenome:HGNC:7223 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MST; TST2; TUM1 Summary This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in duodenum (RPKM 33.5), liver (RPKM 30.3) and 25 other tissues See more Orthologs mouse all
MPV17, Official Symbol MPV17provided by HGNC Official Full Name mitochondrial inner membrane protein MPV17provided by HGNC Primary source HGNC:HGNC:7224 See related Ensembl:ENSG00000115204 MIM:137960; AllianceGenome:HGNC:7224 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYM1; CMT2EE; MTDPS6 Summary This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 8.6), thyroid (RPKM 7.8) and 25 other tissues See more Orthologs mouse all