psui3905/ncbi_genes_summary huggingface dataset:
TRDJ1, Official Symbol TRDJ1provided by HGNC Official Full Name T cell receptor delta joining 1provided by HGNC Primary source HGNC:HGNC:12257 See related Ensembl:ENSG00000211825 IMGT/GENE-DB:TRDJ1; AllianceGenome:HGNC:12257 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRD Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDJ2, Official Symbol TRDJ2provided by HGNC Official Full Name T cell receptor delta joining 2provided by HGNC Primary source HGNC:HGNC:12258 See related Ensembl:ENSG00000211827 IMGT/GENE-DB:TRDJ2; AllianceGenome:HGNC:12258 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDJ3, Official Symbol TRDJ3provided by HGNC Official Full Name T cell receptor delta joining 3provided by HGNC Primary source HGNC:HGNC:12259 See related Ensembl:ENSG00000211828 IMGT/GENE-DB:TRDJ3; AllianceGenome:HGNC:12259 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDJ4, Official Symbol TRDJ4provided by HGNC Official Full Name T cell receptor delta joining 4provided by HGNC Primary source HGNC:HGNC:12260 See related Ensembl:ENSG00000211826 IMGT/GENE-DB:TRDJ4; AllianceGenome:HGNC:12260 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDMT1, Official Symbol TRDMT1provided by HGNC Official Full Name tRNA aspartic acid methyltransferase 1provided by HGNC Primary source HGNC:HGNC:2977 See related Ensembl:ENSG00000107614 MIM:602478; AllianceGenome:HGNC:2977 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DMNT2; DNMT2; PUMET; RNMT1; MHSAIIP Summary This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010] Expression Ubiquitous expression in thyroid (RPKM 1.0), endometrium (RPKM 0.6) and 25 other tissues See more Orthologs mouse all
TRDN, Official Symbol TRDNprovided by HGNC Official Full Name triadinprovided by HGNC Primary source HGNC:HGNC:12261 See related Ensembl:ENSG00000186439 MIM:603283; AllianceGenome:HGNC:12261 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TDN; CPVT5; TRISK; CARDAR Summary This gene encodes an integral membrane protein found in skeletal and cardiac muscle. The encoded protein plays a role in skeletal muscle excitation-contraction coupling as part of the calcium release complex and is required for normal skeletal muscle strength. This protein indirectly links triads and microtubules in skeletal muscle. Mutations in this gene are associated with cardiac arrythmia syndrome and some variants in this gene may be associated with sudden cardiac death. [provided by RefSeq, May 2022] Expression Biased expression in heart (RPKM 24.6), prostate (RPKM 6.0) and 2 other tissues See more Orthologs mouse all
TRDN-AS1, Official Symbol TRDN-AS1provided by HGNC Official Full Name TRDN antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40592 See related Ensembl:ENSG00000235535 AllianceGenome:HGNC:40592 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HRAT13 Expression Restricted expression toward heart (RPKM 15.3) See more
TRDV1, Official Symbol TRDV1provided by HGNC Official Full Name T cell receptor delta variable 1provided by HGNC Primary source HGNC:HGNC:12262 See related Ensembl:ENSG00000211804 IMGT/GENE-DB:TRDV1; AllianceGenome:HGNC:12262 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hDV101S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDV2, Official Symbol TRDV2provided by HGNC Official Full Name T cell receptor delta variable 2provided by HGNC Primary source HGNC:HGNC:12263 See related Ensembl:ENSG00000211821 IMGT/GENE-DB:TRDV2; AllianceGenome:HGNC:12263 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hDV102S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TRDV3, Official Symbol TRDV3provided by HGNC Official Full Name T cell receptor delta variable 3provided by HGNC Primary source HGNC:HGNC:12264 See related Ensembl:ENSG00000256590 IMGT/GENE-DB:TRDV3; AllianceGenome:HGNC:12264 Gene type other RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hDV103S1 Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016] Annotation information Annotation category: partial on reference assembly
TREH, Official Symbol TREHprovided by HGNC Official Full Name trehalaseprovided by HGNC Primary source HGNC:HGNC:12266 See related Ensembl:ENSG00000118094 MIM:275360; AllianceGenome:HGNC:12266 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRE; TREA; TREHD Summary This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Expression Biased expression in duodenum (RPKM 44.4), small intestine (RPKM 43.7) and 1 other tissue See more Orthologs mouse all
TREM1, Official Symbol TREM1provided by HGNC Official Full Name triggering receptor expressed on myeloid cells 1provided by HGNC Primary source HGNC:HGNC:17760 See related Ensembl:ENSG00000124731 MIM:605085; AllianceGenome:HGNC:17760 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD354; TREM-1 Summary This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] Expression Biased expression in bone marrow (RPKM 10.0), appendix (RPKM 9.0) and 7 other tissues See more Orthologs mouse all
TREM2, Official Symbol TREM2provided by HGNC Official Full Name triggering receptor expressed on myeloid cells 2provided by HGNC Primary source HGNC:HGNC:17761 See related Ensembl:ENSG00000095970 MIM:605086; AllianceGenome:HGNC:17761 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c Summary This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] Expression Broad expression in brain (RPKM 11.5), lung (RPKM 7.7) and 14 other tissues See more Orthologs mouse all
TREML1, Official Symbol TREML1provided by HGNC Official Full Name triggering receptor expressed on myeloid cells like 1provided by HGNC Primary source HGNC:HGNC:20434 See related Ensembl:ENSG00000161911 MIM:609714; AllianceGenome:HGNC:20434 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3 Summary This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] Expression Biased expression in bone marrow (RPKM 1.9), lymph node (RPKM 1.7) and 10 other tissues See more Orthologs all
TREML2, Official Symbol TREML2provided by HGNC Official Full Name triggering receptor expressed on myeloid cells like 2provided by HGNC Primary source HGNC:HGNC:21092 See related Ensembl:ENSG00000112195 MIM:609715; AllianceGenome:HGNC:21092 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TLT2; TLT-2; C6orf76; dJ238O23.1 Summary TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008] Expression Biased expression in bone marrow (RPKM 5.6), lymph node (RPKM 5.1) and 6 other tissues See more Orthologs mouse all
TREML4, Official Symbol TREML4provided by HGNC Official Full Name triggering receptor expressed on myeloid cells like 4provided by HGNC Primary source HGNC:HGNC:30807 See related Ensembl:ENSG00000188056 MIM:614664; AllianceGenome:HGNC:30807 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TLT4; TLT-4 Summary Predicted to enable signaling receptor activity. Involved in positive regulation of toll-like receptor 7 signaling pathway. Predicted to be located in endoplasmic reticulum. Predicted to be active in cell surface. Predicted to colocalize with endosome membrane and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
TRERF1, Official Symbol TRERF1provided by HGNC Official Full Name transcriptional regulating factor 1provided by HGNC Primary source HGNC:HGNC:18273 See related Ensembl:ENSG00000124496 MIM:610322; AllianceGenome:HGNC:18273 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAPA; BCAR2; TREP132; TReP-132; HSA277276; dJ139D8.5 Summary This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in testis (RPKM 2.9), bone marrow (RPKM 2.6) and 24 other tissues See more Orthologs mouse all
TREX1, Official Symbol TREX1provided by HGNC Official Full Name three prime repair exonuclease 1provided by HGNC Primary source HGNC:HGNC:12269 See related Ensembl:ENSG00000213689 MIM:606609; AllianceGenome:HGNC:12269 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRV; AGS1; DRN3; HERNS; RVCLS Summary This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012] Annotation information Note: GeneID 11277 was annotated as a single gene with two non-overlapping coding regions. GeneID 11277 now represents only the downstream coding region encoding three prime repair exonuclease 1. The upstream coding region is represented by geneID 84126. [29 May 2007] Expression Ubiquitous expression in spleen (RPKM 9.5), lymph node (RPKM 7.7) and 25 other tissues See more Orthologs mouse all
TREX2, Official Symbol TREX2provided by HGNC Official Full Name three prime repair exonuclease 2provided by HGNC Primary source HGNC:HGNC:12270 See related Ensembl:ENSG00000183479 MIM:300370; AllianceGenome:HGNC:12270 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a nuclear protein with 3' to 5' exonuclease activity. The encoded protein participates in double-stranded DNA break repair, and may interact with DNA polymerase delta. [provided by RefSeq, Nov 2012] Expression Biased expression in skin (RPKM 5.9), spleen (RPKM 0.7) and 5 other tissues See more Orthologs mouse all
TRG-AS1, Official Symbol TRG-AS1provided by HGNC Official Full Name T cell receptor gamma locus antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48974 See related Ensembl:ENSG00000281103 AllianceGenome:HGNC:48974 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRGV Expression Biased expression in spleen (RPKM 8.0), lymph node (RPKM 2.9) and 10 other tissues See more
TRGC1, Official Symbol TRGC1provided by HGNC Official Full Name T cell receptor gamma constant 1provided by HGNC Primary source HGNC:HGNC:12275 See related Ensembl:ENSG00000211689 IMGT/GENE-DB:TRGC1; MIM:186970; AllianceGenome:HGNC:12275 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1; TARP; TCRG; TCRGC1 Summary Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGC2, Official Symbol TRGC2provided by HGNC Official Full Name T cell receptor gamma constant 2provided by HGNC Primary source HGNC:HGNC:12276 See related Ensembl:ENSG00000227191 IMGT/GENE-DB:TRGC2; MIM:615450; AllianceGenome:HGNC:12276 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCRGC2; TRGC2(2X); TRGC2(3X) Summary Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGJ1, Official Symbol TRGJ1provided by HGNC Official Full Name T cell receptor gamma joining 1provided by HGNC Primary source HGNC:HGNC:12277 See related Ensembl:ENSG00000211690 IMGT/GENE-DB:TRGJ1; AllianceGenome:HGNC:12277 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as J1; TCRGJ1 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGJ2, Official Symbol TRGJ2provided by HGNC Official Full Name T cell receptor gamma joining 2provided by HGNC Primary source HGNC:HGNC:12278 See related Ensembl:ENSG00000211687 IMGT/GENE-DB:TRGJ2; AllianceGenome:HGNC:12278 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as J2; TCRGJ2 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGJP, Official Symbol TRGJPprovided by HGNC Official Full Name T cell receptor gamma joining Pprovided by HGNC Primary source HGNC:HGNC:12279 See related Ensembl:ENSG00000211691 IMGT/GENE-DB:TRGJP; AllianceGenome:HGNC:12279 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JP; TCRGJP Annotation information Annotation category: partial on reference assembly
TRGJP1, Official Symbol TRGJP1provided by HGNC Official Full Name T cell receptor gamma joining P1provided by HGNC Primary source HGNC:HGNC:12280 See related Ensembl:ENSG00000211692 IMGT/GENE-DB:TRGJP1; AllianceGenome:HGNC:12280 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JP1; TCRGJP1 Annotation information Annotation category: partial on reference assembly
TRGJP2, Official Symbol TRGJP2provided by HGNC Official Full Name T cell receptor gamma joining P2provided by HGNC Primary source HGNC:HGNC:12281 See related Ensembl:ENSG00000211688 IMGT/GENE-DB:TRGJP2; AllianceGenome:HGNC:12281 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JP2; TCRGJP2 Annotation information Annotation category: partial on reference assembly
TRGV1, Official Symbol TRGV1provided by HGNC Official Full Name T cell receptor gamma variable 1 (non-functional)provided by HGNC Primary source HGNC:HGNC:12284 See related Ensembl:ENSG00000211701 IMGT/GENE-DB:TRGV1; AllianceGenome:HGNC:12284 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S1P; TCRGV1 Summary Predicted to be involved in adaptive immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
TRGV2, Official Symbol TRGV2provided by HGNC Official Full Name T cell receptor gamma variable 2provided by HGNC Primary source HGNC:HGNC:12287 See related Ensembl:ENSG00000233306 IMGT/GENE-DB:TRGV2; AllianceGenome:HGNC:12287 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VIS2; TCRGV2 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGV3, Official Symbol TRGV3provided by HGNC Official Full Name T cell receptor gamma variable 3provided by HGNC Primary source HGNC:HGNC:12288 See related Ensembl:ENSG00000211699 IMGT/GENE-DB:TRGV3; AllianceGenome:HGNC:12288 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S3; TCRGV3 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGV4, Official Symbol TRGV4provided by HGNC Official Full Name T cell receptor gamma variable 4provided by HGNC Primary source HGNC:HGNC:12289 See related Ensembl:ENSG00000211698 IMGT/GENE-DB:TRGV4; AllianceGenome:HGNC:12289 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S4; TCRGV4 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGV5, Official Symbol TRGV5provided by HGNC Official Full Name T cell receptor gamma variable 5provided by HGNC Primary source HGNC:HGNC:12290 See related Ensembl:ENSG00000211697 IMGT/GENE-DB:TRGV5; AllianceGenome:HGNC:12290 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S5; TCRGV5 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGV5P, Official Symbol TRGV5Pprovided by HGNC Official Full Name T cell receptor gamma variable 5P (pseudogene)provided by HGNC Primary source HGNC:HGNC:12291 See related Ensembl:ENSG00000228668 IMGT/GENE-DB:TRGV5P; AllianceGenome:HGNC:12291 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S5P; TCRGV5P
TRGV6, Official Symbol TRGV6provided by HGNC Official Full Name T cell receptor gamma variable 6 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12292 See related IMGT/GENE-DB:TRGV6; AllianceGenome:HGNC:12292 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S5P; V1S6P; TCRGV6; TCRGV5P
TRGV7, Official Symbol TRGV7provided by HGNC Official Full Name T cell receptor gamma variable 7 (pseudogene)provided by HGNC Primary source HGNC:HGNC:12293 See related Ensembl:ENSG00000249978 IMGT/GENE-DB:TRGV7; AllianceGenome:HGNC:12293 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S7P; TCRGV7
TRGV8, Official Symbol TRGV8provided by HGNC Official Full Name T cell receptor gamma variable 8provided by HGNC Primary source HGNC:HGNC:12294 See related Ensembl:ENSG00000211696 IMGT/GENE-DB:TRGV8; AllianceGenome:HGNC:12294 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1S8; TCRGV8 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGV9, Official Symbol TRGV9provided by HGNC Official Full Name T cell receptor gamma variable 9provided by HGNC Primary source HGNC:HGNC:12295 See related Ensembl:ENSG00000211695 IMGT/GENE-DB:TRGV9; AllianceGenome:HGNC:12295 Gene type other RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V2; TRGC1; TCRGV9 Summary Predicted to be involved in adaptive immune response and innate immune response. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Annotation category: partial on reference assembly
TRGVB, Official Symbol TRGVBprovided by HGNC Official Full Name T cell receptor gamma variable B (pseudogene)provided by HGNC Primary source HGNC:HGNC:12297 See related IMGT/GENE-DB:TRGVB; AllianceGenome:HGNC:12297 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V6P; TCRGVB
TRH, Official Symbol TRHprovided by HGNC Official Full Name thyrotropin releasing hormoneprovided by HGNC Primary source HGNC:HGNC:12298 See related Ensembl:ENSG00000170893 MIM:613879; AllianceGenome:HGNC:12298 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRF; Pro-TRH Summary This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013] Expression Biased expression in endometrium (RPKM 11.5), bone marrow (RPKM 1.1) and 1 other tissue See more Orthologs mouse all
TRHDE, Official Symbol TRHDEprovided by HGNC Official Full Name thyrotropin releasing hormone degrading enzymeprovided by HGNC Primary source HGNC:HGNC:30748 See related Ensembl:ENSG00000072657 MIM:606950; AllianceGenome:HGNC:30748 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP-II; PGPEP2; TRH-DE Summary This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008] Expression Broad expression in brain (RPKM 3.0), fat (RPKM 2.9) and 17 other tissues See more Orthologs mouse all
TRHR, Official Symbol TRHRprovided by HGNC Official Full Name thyrotropin releasing hormone receptorprovided by HGNC Primary source HGNC:HGNC:12299 See related Ensembl:ENSG00000174417 MIM:188545; AllianceGenome:HGNC:12299 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHNG7; TRH-R Summary This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all
TRIAP1, Official Symbol TRIAP1provided by HGNC Official Full Name TP53 regulated inhibitor of apoptosis 1provided by HGNC Primary source HGNC:HGNC:26937 See related Ensembl:ENSG00000170855 MIM:614943; AllianceGenome:HGNC:26937 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WF-1; MDM35; P53CSV; HSPC132 Summary Enables p53 binding activity. Contributes to phosphatidic acid transfer activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of apoptotic process; and positive regulation of phospholipid transport. Located in mitochondrial intermembrane space and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 17.2), liver (RPKM 15.9) and 25 other tissues See more Orthologs mouse all
TRIB1, Official Symbol TRIB1provided by HGNC Official Full Name tribbles pseudokinase 1provided by HGNC Primary source HGNC:HGNC:16891 See related Ensembl:ENSG00000173334 MIM:609461; AllianceGenome:HGNC:16891 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1 Summary Enables mitogen-activated protein kinase kinase binding activity and protein kinase inhibitor activity. Involved in several processes, including JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; and regulation of protein kinase activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 87.7), liver (RPKM 53.0) and 20 other tissues See more Orthologs mouse all
TRIB2, Official Symbol TRIB2provided by HGNC Official Full Name tribbles pseudokinase 2provided by HGNC Primary source HGNC:HGNC:30809 See related Ensembl:ENSG00000071575 MIM:609462; AllianceGenome:HGNC:30809 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C5FW; TRB2; GS3955 Summary This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] Expression Ubiquitous expression in ovary (RPKM 31.3), spleen (RPKM 27.6) and 24 other tissues See more Orthologs mouse all
TRIB3, Official Symbol TRIB3provided by HGNC Official Full Name tribbles pseudokinase 3provided by HGNC Primary source HGNC:HGNC:16228 See related Ensembl:ENSG00000101255 MIM:607898; AllianceGenome:HGNC:16228 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIPK; SINK; TRB3; SKIP3; C20orf97 Summary The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Broad expression in thyroid (RPKM 19.9), liver (RPKM 5.0) and 16 other tissues See more Orthologs mouse all