psui3905/ncbi_genes_summary huggingface dataset:
METTL1, Official Symbol METTL1provided by HGNC Official Full Name methyltransferase 1, tRNA methylguanosineprovided by HGNC Primary source HGNC:HGNC:7030 See related Ensembl:ENSG00000037897 MIM:604466; AllianceGenome:HGNC:7030 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRM8; TRMT8; C12orf1; YDL201w Summary This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 7.6), thyroid (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
METTL13, Official Symbol METTL13provided by HGNC Official Full Name methyltransferase 13, eEF1A N-terminus and K55provided by HGNC Primary source HGNC:HGNC:24248 See related Ensembl:ENSG00000010165 MIM:617987; AllianceGenome:HGNC:24248 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as feat; DFNM1; CGI-01; DFNB26; DFNB26M; KIAA0859; EEF1AKNMT; 5630401D24Rik Summary Predicted to enable methyltransferase activity. Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 10.7), lymph node (RPKM 7.3) and 25 other tissues See more Orthologs mouse all
METTL14, Official Symbol METTL14provided by HGNC Official Full Name methyltransferase 14, N6-adenosine-methyltransferase subunitprovided by HGNC Primary source HGNC:HGNC:29330 See related Ensembl:ENSG00000145388 MIM:616504; AllianceGenome:HGNC:29330 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hMETTL14 Summary Enables mRNA binding activity. Contributes to mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA metabolic process; negative regulation of hematopoietic progenitor cell differentiation; and positive regulation of translation. Located in nucleoplasm. Part of RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.4), thyroid (RPKM 7.2) and 25 other tissues See more Orthologs mouse all
METTL14-DT, Official Symbol METTL14-DTprovided by HGNC Official Full Name METTL14 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:53367 See related Ensembl:ENSG00000281731 AllianceGenome:HGNC:53367 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
METTL15, Official Symbol METTL15provided by HGNC Official Full Name methyltransferase 15, mitochondrial 12S rRNA N4-cytidineprovided by HGNC Primary source HGNC:HGNC:26606 See related Ensembl:ENSG00000169519 MIM:618711; AllianceGenome:HGNC:26606 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METT5D1 Summary Predicted to enable rRNA (cytosine-N4-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 2.9), adrenal (RPKM 2.8) and 25 other tissues See more Orthologs mouse all
METTL15P3, Official Symbol METTL15P3provided by HGNC Official Full Name methyltransferase like 15 pseudogene 3provided by HGNC Primary source HGNC:HGNC:39558 See related Ensembl:ENSG00000224396 AllianceGenome:HGNC:39558 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
METTL16, Official Symbol METTL16provided by HGNC Official Full Name methyltransferase 16, RNA N6-adenosineprovided by HGNC Primary source HGNC:HGNC:28484 See related Ensembl:ENSG00000127804 AllianceGenome:HGNC:28484 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METT10D Summary Enables RNA binding activity and RNA methyltransferase activity. Involved in RNA modification and regulation of mRNA metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 7.5), thyroid (RPKM 6.7) and 25 other tissues See more Orthologs mouse all
METTL17, Official Symbol METTL17provided by HGNC Official Full Name methyltransferase like 17provided by HGNC Primary source HGNC:HGNC:19280 See related Ensembl:ENSG00000165792 MIM:616091; AllianceGenome:HGNC:19280 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METT11D1 Summary Predicted to enable S-adenosyl-L-methionine binding activity and mitochondrial ribosome binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 22.3), lymph node (RPKM 19.6) and 25 other tissues See more Orthologs mouse all
METTL18, Official Symbol METTL18provided by HGNC Official Full Name methyltransferase 18, RPL3 N3(tau)-histidineprovided by HGNC Primary source HGNC:HGNC:28793 See related Ensembl:ENSG00000171806 MIM:615255; AllianceGenome:HGNC:28793 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPM1; AsTP2; C1orf156 Summary Enables heat shock protein binding activity and protein-L-histidine N-tele-methyltransferase activity. Involved in peptidyl-lysine monomethylation; regulation of gene expression; and regulation of ribosome biogenesis. Located in cytosol and nucleolus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 4.6), thyroid (RPKM 3.3) and 25 other tissues See more Orthologs mouse all
METTL21A, Official Symbol METTL21Aprovided by HGNC Official Full Name methyltransferase 21A, HSPA lysineprovided by HGNC Primary source HGNC:HGNC:30476 See related Ensembl:ENSG00000144401 MIM:615257; AllianceGenome:HGNC:30476 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM119A; HCA557b; HSPA-KMT Summary Enables ATPase binding activity; Hsp70 protein binding activity; and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 1.8), spleen (RPKM 1.7) and 25 other tissues See more Orthologs mouse all
METTL21AP1, Official Symbol METTL21AP1provided by HGNC Official Full Name methyltransferase like 21A pseudogene 1provided by HGNC Primary source HGNC:HGNC:41921 See related Ensembl:ENSG00000229623 AllianceGenome:HGNC:41921 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
METTL21C, Official Symbol METTL21Cprovided by HGNC Official Full Name methyltransferase 21C, AARS1 lysineprovided by HGNC Primary source HGNC:HGNC:33717 See related Ensembl:ENSG00000139780 MIM:615259; AllianceGenome:HGNC:33717 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C13orf39 Summary Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in protein methylation. Located in nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs all
METTL21EP, Official Symbol METTL21EPprovided by HGNC Official Full Name methyltransferase like 21E, pseudogeneprovided by HGNC Primary source HGNC:HGNC:41948 See related Ensembl:ENSG00000250878 AllianceGenome:HGNC:41948 Gene type pseudo RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METTL21CP1 Summary Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine trimethylation. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in heart (RPKM 1.2), brain (RPKM 0.1) and 4 other tissues See more
METTL22, Official Symbol METTL22provided by HGNC Official Full Name methyltransferase 22, Kin17 lysineprovided by HGNC Primary source HGNC:HGNC:28368 See related Ensembl:ENSG00000067365 MIM:615261; AllianceGenome:HGNC:28368 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C16orf68 Summary This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in testis (RPKM 2.7), endometrium (RPKM 1.3) and 25 other tissues See more Orthologs mouse all
METTL23, Official Symbol METTL23provided by HGNC Official Full Name methyltransferase 23, arginineprovided by HGNC Primary source HGNC:HGNC:26988 See related Ensembl:ENSG00000181038 MIM:615262; AllianceGenome:HGNC:26988 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRT44; C17orf95 Summary The protein encoded by this gene functions as a transcription factor regulator in the transcriptional pathway for human cognition. It is a partner of the alpha subunit of the GA-binding protein transcription factor. Mutations in this gene cause mild autosomal recessive intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Ubiquitous expression in testis (RPKM 11.1), thyroid (RPKM 8.5) and 25 other tissues See more Orthologs mouse all
METTL24, Official Symbol METTL24provided by HGNC Official Full Name methyltransferase like 24provided by HGNC Primary source HGNC:HGNC:21566 See related Ensembl:ENSG00000053328 AllianceGenome:HGNC:21566 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf186 Summary Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 3.7), gall bladder (RPKM 2.6) and 20 other tissues See more Orthologs mouse all
METTL25, Official Symbol METTL25provided by HGNC Official Full Name methyltransferase like 25provided by HGNC Primary source HGNC:HGNC:26228 See related Ensembl:ENSG00000127720 AllianceGenome:HGNC:26228 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C12orf26 Summary Predicted to enable methyltransferase activity. Predicted to be involved in methylation. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
METTL26, Official Symbol METTL26provided by HGNC Official Full Name methyltransferase like 26provided by HGNC Primary source HGNC:HGNC:14141 See related Ensembl:ENSG00000130731 AllianceGenome:HGNC:14141 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JFP2; C16orf13 Expression Ubiquitous expression in kidney (RPKM 12.8), ovary (RPKM 12.0) and 25 other tissues See more Orthologs mouse all
METTL27, Official Symbol METTL27provided by HGNC Official Full Name methyltransferase like 27provided by HGNC Primary source HGNC:HGNC:19068 See related Ensembl:ENSG00000165171 MIM:612546; AllianceGenome:HGNC:19068 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WBSCR27 Summary This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 1.9), prostate (RPKM 1.9) and 24 other tissues See more Orthologs mouse all
METTL2A, Official Symbol METTL2Aprovided by HGNC Official Full Name methyltransferase 2A, tRNA N3-cytidineprovided by HGNC Primary source HGNC:HGNC:25755 See related Ensembl:ENSG00000087995 MIM:618902; AllianceGenome:HGNC:25755 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METTL2 Summary Enables tRNA (cytosine-3-)-methyltransferase activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 6.2), thyroid (RPKM 6.2) and 25 other tissues See more Orthologs mouse all
METTL2B, Official Symbol METTL2Bprovided by HGNC Official Full Name methyltransferase 2B, tRNA N3-cytidineprovided by HGNC Primary source HGNC:HGNC:18272 See related Ensembl:ENSG00000165055 MIM:607846; AllianceGenome:HGNC:18272 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as METL; METTL2; METTL2A; PSENIP1 Summary This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 7.8), fat (RPKM 7.8) and 25 other tissues See more Orthologs all
METTL3, Official Symbol METTL3provided by HGNC Official Full Name methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunitprovided by HGNC Primary source HGNC:HGNC:17563 See related Ensembl:ENSG00000165819 MIM:612472; AllianceGenome:HGNC:17563 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M6A; IME4; Spo8; MT-A70; hMETTL3 Summary This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 23.5), testis (RPKM 22.1) and 25 other tissues See more Orthologs mouse all
METTL4, Official Symbol METTL4provided by HGNC Official Full Name methyltransferase 4, N6-adenosineprovided by HGNC Primary source HGNC:HGNC:24726 See related Ensembl:ENSG00000101574 MIM:619626; AllianceGenome:HGNC:24726 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HsT661 Summary Enables RNA methyltransferase activity and site-specific DNA-methyltransferase (adenine-specific) activity. Involved in nucleic acid metabolic process; regulation of RNA metabolic process; and regulation of mitochondrial DNA replication. Located in cytosol; mitochondrial matrix; and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 4.0), thyroid (RPKM 3.9) and 25 other tissues See more Orthologs mouse all
METTL5, Official Symbol METTL5provided by HGNC Official Full Name methyltransferase 5, N6-adenosineprovided by HGNC Primary source HGNC:HGNC:25006 See related Ensembl:ENSG00000138382 MIM:618628; AllianceGenome:HGNC:25006 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRT72; HSPC133 Summary Enables S-adenosyl-L-methionine binding activity and rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation and rRNA methylation. Located in nucleus; postsynapse; and presynapse. Implicated in autosomal recessive intellectual developmental disorder-72. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 27.8), thyroid (RPKM 17.4) and 25 other tissues See more Orthologs mouse all
METTL6, Official Symbol METTL6provided by HGNC Official Full Name methyltransferase 6, tRNA N3-cytidineprovided by HGNC Primary source HGNC:HGNC:28343 See related Ensembl:ENSG00000206562 MIM:618903; AllianceGenome:HGNC:28343 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hMETTL6 Summary Enables enzyme binding activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 1.5), brain (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
METTL8, Official Symbol METTL8provided by HGNC Official Full Name methyltransferase 8, tRNA N3-cytidineprovided by HGNC Primary source HGNC:HGNC:25856 See related Ensembl:ENSG00000123600 MIM:609525; AllianceGenome:HGNC:25856 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIP Summary Enables mRNA methyltransferase activity. Involved in mRNA methylation. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 2.5), esophagus (RPKM 2.0) and 24 other tissues See more Orthologs mouse all
METTL9, Official Symbol METTL9provided by HGNC Official Full Name methyltransferase 9, His-X-His N1(pi)-histidineprovided by HGNC Primary source HGNC:HGNC:24586 See related Ensembl:ENSG00000197006 MIM:609388; AllianceGenome:HGNC:24586 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DREV; PAP1; DREV1; CGI-81; hMETTL9 Summary Enables protein-L-histidine N-pros-methyltransferase activity. Predicted to be involved in methylation. Is active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 38.8), adrenal (RPKM 37.6) and 25 other tissues See more Orthologs mouse all
MEX3A, Official Symbol MEX3Aprovided by HGNC Official Full Name mex-3 RNA binding family member Aprovided by HGNC Primary source HGNC:HGNC:33482 See related Ensembl:ENSG00000254726 MIM:611007; AllianceGenome:HGNC:33482 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RKHD4; MEX-3A; RNF162 Summary Enables RNA binding activity. Located in P-body and cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in endometrium (RPKM 3.0), ovary (RPKM 2.6) and 16 other tissues See more Orthologs mouse all
MEX3B, Official Symbol MEX3Bprovided by HGNC Official Full Name mex-3 RNA binding family member Bprovided by HGNC Primary source HGNC:HGNC:25297 See related Ensembl:ENSG00000183496 MIM:611008; AllianceGenome:HGNC:25297 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RKHD3; MEX-3B; RNF195 Summary This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012] Expression Biased expression in testis (RPKM 20.7), endometrium (RPKM 5.5) and 7 other tissues See more Orthologs mouse all
MEX3C, Official Symbol MEX3Cprovided by HGNC Official Full Name mex-3 RNA binding family member Cprovided by HGNC Primary source HGNC:HGNC:28040 See related Ensembl:ENSG00000176624 MIM:611005; AllianceGenome:HGNC:28040 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RKHD2; BM-013; MEX-3C; RNF194 Summary This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009] Expression Broad expression in testis (RPKM 32.6), lymph node (RPKM 11.1) and 24 other tissues See more Orthologs mouse all
MEX3D, Official Symbol MEX3Dprovided by HGNC Official Full Name mex-3 RNA binding family member Dprovided by HGNC Primary source HGNC:HGNC:16734 See related Ensembl:ENSG00000181588 MIM:611009; AllianceGenome:HGNC:16734 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEX3; TINO; RKHD1; MEX-3D; RNF193; OK/SW-cl.4 Summary Enables mRNA 3'-UTR AU-rich region binding activity. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 6.0), fat (RPKM 4.9) and 24 other tissues See more Orthologs mouse all
MFAP1, Official Symbol MFAP1provided by HGNC Official Full Name microfibril associated protein 1provided by HGNC Primary source HGNC:HGNC:7032 See related Ensembl:ENSG00000140259 MIM:600215; AllianceGenome:HGNC:7032 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMP Summary Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in centrosome; microfibril; and nucleoplasm. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 15.2), testis (RPKM 14.4) and 25 other tissues See more Orthologs mouse all
MFAP2, Official Symbol MFAP2provided by HGNC Official Full Name microfibril associated protein 2provided by HGNC Primary source HGNC:HGNC:7033 See related Ensembl:ENSG00000117122 MIM:156790; AllianceGenome:HGNC:7033 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAGP; MAGP1; MAGP-1 Summary Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] Expression Broad expression in endometrium (RPKM 22.6), gall bladder (RPKM 22.5) and 16 other tissues See more Orthologs mouse all
MFAP3, Official Symbol MFAP3provided by HGNC Official Full Name microfibril associated protein 3provided by HGNC Primary source HGNC:HGNC:7034 See related Ensembl:ENSG00000037749 MIM:600491; AllianceGenome:HGNC:7034 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be located in extracellular region. Predicted to be active in cytoplasm; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 9.1), urinary bladder (RPKM 9.1) and 25 other tissues See more Orthologs mouse all
MFAP3L, Official Symbol MFAP3Lprovided by HGNC Official Full Name microfibril associated protein 3 likeprovided by HGNC Primary source HGNC:HGNC:29083 See related Ensembl:ENSG00000198948 MIM:616523; AllianceGenome:HGNC:29083 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NYD-sp9 Summary Located in several cellular components, including cell junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in kidney (RPKM 7.1), brain (RPKM 6.1) and 14 other tissues See more Orthologs mouse all
MFAP4, Official Symbol MFAP4provided by HGNC Official Full Name microfibril associated protein 4provided by HGNC Primary source HGNC:HGNC:7035 See related Ensembl:ENSG00000166482 MIM:600596; AllianceGenome:HGNC:7035 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] Expression Broad expression in gall bladder (RPKM 378.1), lung (RPKM 320.6) and 18 other tissues See more Orthologs mouse all
MFAP5, Official Symbol MFAP5provided by HGNC Official Full Name microfibril associated protein 5provided by HGNC Primary source HGNC:HGNC:29673 See related Ensembl:ENSG00000197614 MIM:601103; AllianceGenome:HGNC:29673 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AAT9; MP25; MAGP2; MAGP-2; MFAP-5 Summary This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] Expression Biased expression in fat (RPKM 53.2), endometrium (RPKM 51.6) and 11 other tissues See more Orthologs mouse all
MFF, Official Symbol MFFprovided by HGNC Official Full Name mitochondrial fission factorprovided by HGNC Primary source HGNC:HGNC:24858 See related Ensembl:ENSG00000168958 MIM:614785; AllianceGenome:HGNC:24858 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMPF2; GL004; C2orf33 Summary This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] Expression Broad expression in testis (RPKM 68.3), brain (RPKM 24.9) and 25 other tissues See more Orthologs mouse all
MFF-DT, Official Symbol MFF-DTprovided by HGNC Official Full Name MFF divergent transcriptprovided by HGNC Primary source HGNC:HGNC:41067 See related Ensembl:ENSG00000236432 AllianceGenome:HGNC:41067 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
MFFP2, Official Symbol MFFP2provided by HGNC Official Full Name MFF pseudogene 2provided by HGNC Primary source HGNC:HGNC:54540 See related AllianceGenome:HGNC:54540 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MFGE8, Official Symbol MFGE8provided by HGNC Official Full Name milk fat globule EGF and factor V/VIII domain containingprovided by HGNC Primary source HGNC:HGNC:7036 See related Ensembl:ENSG00000140545 MIM:602281; AllianceGenome:HGNC:7036 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888 Summary This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Expression Broad expression in heart (RPKM 68.1), endometrium (RPKM 47.7) and 22 other tissues See more Orthologs mouse all
MFHAS1, Official Symbol MFHAS1provided by HGNC Official Full Name multifunctional ROCO family signaling regulator 1provided by HGNC Primary source HGNC:HGNC:16982 See related Ensembl:ENSG00000147324 MIM:605352; AllianceGenome:HGNC:16982 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MASL1; ROCO4; LRRC65 Summary Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lung (RPKM 8.7), spleen (RPKM 8.4) and 25 other tissues See more Orthologs mouse all
MFN1, Official Symbol MFN1provided by HGNC Official Full Name mitofusin 1provided by HGNC Primary source HGNC:HGNC:18262 See related Ensembl:ENSG00000171109 MIM:608506; AllianceGenome:HGNC:18262 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hfzo1; hfzo2 Summary The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 9.7), prostate (RPKM 9.7) and 25 other tissues See more Orthologs mouse all
MFN1P1, Official Symbol MFN1P1provided by HGNC Official Full Name MFN1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:55050 See related Ensembl:ENSG00000233874 AllianceGenome:HGNC:55050 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MFN2, Official Symbol MFN2provided by HGNC Official Full Name mitofusin 2provided by HGNC Primary source HGNC:HGNC:16877 See related Ensembl:ENSG00000116688 MIM:608507; AllianceGenome:HGNC:16877 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSG; MSL; MARF; CMT2A; CPRP1; CMT2A2; HMSN6A; CMT2A2A; CMT2A2B Summary This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 98.6), thyroid (RPKM 37.1) and 24 other tissues See more Orthologs mouse all
MFNG, Official Symbol MFNGprovided by HGNC Official Full Name MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseprovided by HGNC Primary source HGNC:HGNC:7038 See related Ensembl:ENSG00000100060 MIM:602577; AllianceGenome:HGNC:7038 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the LFNG (GeneID: 3955) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018] Expression Broad expression in lymph node (RPKM 25.3), spleen (RPKM 22.3) and 23 other tissues See more Orthologs mouse all
MFRP, Official Symbol MFRPprovided by HGNC Official Full Name membrane frizzled-related proteinprovided by HGNC Primary source HGNC:HGNC:18121 See related Ensembl:ENSG00000235718 MIM:606227; AllianceGenome:HGNC:18121 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RD6; NNO2; CTRP5; MCOP5 Summary This gene encodes a member of the frizzled-related protein family. The encoded protein plays an important role in eye development and mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic transcript which also encodes C1q and tumor necrosis factor related protein 5 (C1QTNF5). [provided by RefSeq, Jun 2013] Expression Broad expression in gall bladder (RPKM 9.2), fat (RPKM 6.7) and 20 other tissues See more Orthologs mouse all
MFSD1, Official Symbol MFSD1provided by HGNC Official Full Name major facilitator superfamily domain containing 1provided by HGNC Primary source HGNC:HGNC:25874 See related Ensembl:ENSG00000118855 MIM:619976; AllianceGenome:HGNC:25874 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMAP4; Minerva Summary Predicted to enable protein homodimerization activity. Predicted to be involved in protein localization to lysosome and protein stabilization. Predicted to be located in lysosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 32.7), esophagus (RPKM 31.9) and 25 other tissues See more Orthologs mouse all
MFSD10, Official Symbol MFSD10provided by HGNC Official Full Name major facilitator superfamily domain containing 10provided by HGNC Primary source HGNC:HGNC:16894 See related Ensembl:ENSG00000109736 MIM:610977; AllianceGenome:HGNC:16894 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TETRAN; TETTRAN Summary This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009] Expression Ubiquitous expression in bone marrow (RPKM 36.8), spleen (RPKM 13.5) and 24 other tissues See more Orthologs mouse all
MFSD11, Official Symbol MFSD11provided by HGNC Official Full Name major facilitator superfamily domain containing 11provided by HGNC Primary source HGNC:HGNC:25458 See related Ensembl:ENSG00000092931 MIM:620346; AllianceGenome:HGNC:25458 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ET Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 5.3), stomach (RPKM 4.4) and 25 other tissues See more Orthologs mouse all
MFSD12, Official Symbol MFSD12provided by HGNC Official Full Name major facilitator superfamily domain containing 12provided by HGNC Primary source HGNC:HGNC:28299 See related Ensembl:ENSG00000161091 MIM:617745; AllianceGenome:HGNC:28299 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP3501; C19orf28 Summary Enables cysteine transmembrane transporter activity. Involved in cysteine transmembrane transport; pigment metabolic process involved in pigmentation; and regulation of melanin biosynthetic process. Located in lysosome and melanosome. Part of late endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 23.3), skin (RPKM 11.8) and 25 other tissues See more Orthologs mouse all
MFSD13A, Official Symbol MFSD13Aprovided by HGNC Official Full Name major facilitator superfamily domain containing 13Aprovided by HGNC Primary source HGNC:HGNC:26196 See related Ensembl:ENSG00000138111 MIM:620255; AllianceGenome:HGNC:26196 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TMEM180; C10orf77; bA18I14.8 Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 9.0), lung (RPKM 6.4) and 25 other tissues See more Orthologs mouse all
MFSD13B, Official Symbol MFSD13Bprovided by HGNC Official Full Name major facilitator superfamily domain containing 13B (pseudogene)provided by HGNC Primary source HGNC:HGNC:52163 See related Ensembl:ENSG00000230872 AllianceGenome:HGNC:52163 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more Orthologs all
MFSD14A, Official Symbol MFSD14Aprovided by HGNC Official Full Name major facilitator superfamily domain containing 14Aprovided by HGNC Primary source HGNC:HGNC:23363 See related Ensembl:ENSG00000156875 MIM:620347; AllianceGenome:HGNC:23363 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HAIT1; HIAT1 Summary Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within acrosome assembly; sperm mitochondrion organization; and spermatid nucleus differentiation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 31.6), testis (RPKM 26.1) and 25 other tissues See more Orthologs mouse all
MFSD14B, Official Symbol MFSD14Bprovided by HGNC Official Full Name major facilitator superfamily domain containing 14Bprovided by HGNC Primary source HGNC:HGNC:23376 See related Ensembl:ENSG00000148110 MIM:620348; AllianceGenome:HGNC:23376 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIATL1 Summary Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 21.3), lung (RPKM 18.5) and 25 other tissues See more Orthologs mouse all
MFSD1P1, Official Symbol MFSD1P1provided by HGNC Official Full Name major facilitator superfamily domain containing 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:50625 See related AllianceGenome:HGNC:50625 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
MFSD2A, Official Symbol MFSD2Aprovided by HGNC Official Full Name MFSD2 lysolipid transporter A, lysophospholipidprovided by HGNC Primary source HGNC:HGNC:25897 See related Ensembl:ENSG00000168389 MIM:614397; AllianceGenome:HGNC:25897 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NLS1; MFSD2; MCPH15; SLC59A1; HsMFSD2A; NEDMISBA Summary The protein encoded by this gene is a transmembrane protein and sodium-dependent lysophosphatidylcholine transporter. The encoded protein is involved in the establishment of the blood-brain barrier and is required for brain growth and function. Defects in this gene are a cause of a progressive microcephaly syndrome. [provided by RefSeq, Mar 2017] Expression Broad expression in testis (RPKM 27.5), lung (RPKM 23.6) and 14 other tissues See more Orthologs mouse all