psui3905/ncbi_genes_summary huggingface dataset:
FBXO16, Official Symbol FBXO16provided by HGNC Official Full Name F-box protein 16provided by HGNC Primary source HGNC:HGNC:13618 See related Ensembl:ENSG00000214050 MIM:608519; AllianceGenome:HGNC:13618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX16 Summary This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Expression Broad expression in thyroid (RPKM 3.3), brain (RPKM 2.1) and 21 other tissues See more Orthologs mouse all
FBXO17, Official Symbol FBXO17provided by HGNC Official Full Name F-box protein 17provided by HGNC Primary source HGNC:HGNC:18754 See related Ensembl:ENSG00000269190 MIM:609094; AllianceGenome:HGNC:18754 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG4; FBX26; Fbx17; FBXO26 Summary This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in kidney (RPKM 11.1), ovary (RPKM 9.9) and 23 other tissues See more Orthologs mouse all
FBXO2, Official Symbol FBXO2provided by HGNC Official Full Name F-box protein 2provided by HGNC Primary source HGNC:HGNC:13581 See related Ensembl:ENSG00000116661 MIM:607112; AllianceGenome:HGNC:13581 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG1; FBX2; Fbs1; OCP1; NFB42 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 27.1), adrenal (RPKM 10.3) and 11 other tissues See more Orthologs mouse all
FBXO21, Official Symbol FBXO21provided by HGNC Official Full Name F-box protein 21provided by HGNC Primary source HGNC:HGNC:13592 See related Ensembl:ENSG00000135108 MIM:609095; AllianceGenome:HGNC:13592 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX21 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 31.4), ovary (RPKM 26.9) and 25 other tissues See more Orthologs mouse all
FBXO22, Official Symbol FBXO22provided by HGNC Official Full Name F-box protein 22provided by HGNC Primary source HGNC:HGNC:13593 See related Ensembl:ENSG00000167196 MIM:609096; AllianceGenome:HGNC:13593 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX22; FISTC1 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in prostate (RPKM 5.0), kidney (RPKM 4.8) and 25 other tissues See more Orthologs mouse all
FBXO24, Official Symbol FBXO24provided by HGNC Official Full Name F-box protein 24provided by HGNC Primary source HGNC:HGNC:13595 See related Ensembl:ENSG00000106336 MIM:609097; AllianceGenome:HGNC:13595 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX24 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] Expression Restricted expression toward testis (RPKM 14.9) See more Orthologs mouse all
FBXO25, Official Symbol FBXO25provided by HGNC Official Full Name F-box protein 25provided by HGNC Primary source HGNC:HGNC:13596 See related Ensembl:ENSG00000147364 MIM:609098; AllianceGenome:HGNC:13596 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX25 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 13.0), thyroid (RPKM 5.9) and 25 other tissues See more Orthologs mouse all
FBXO27, Official Symbol FBXO27provided by HGNC Official Full Name F-box protein 27provided by HGNC Primary source HGNC:HGNC:18753 See related Ensembl:ENSG00000161243 MIM:609099; AllianceGenome:HGNC:18753 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG5; Fbx27 Summary Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Broad expression in skin (RPKM 7.0), fat (RPKM 5.3) and 21 other tissues See more Orthologs mouse all
FBXO28, Official Symbol FBXO28provided by HGNC Official Full Name F-box protein 28provided by HGNC Primary source HGNC:HGNC:29046 See related Ensembl:ENSG00000143756 MIM:609100; AllianceGenome:HGNC:29046 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx28; DEE100; CENP-30 Summary Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in skin (RPKM 11.4), esophagus (RPKM 8.4) and 25 other tissues See more Orthologs mouse all
FBXO3, Official Symbol FBXO3provided by HGNC Official Full Name F-box protein 3provided by HGNC Primary source HGNC:HGNC:13582 See related Ensembl:ENSG00000110429 MIM:609089; AllianceGenome:HGNC:13582 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBA; FBX3 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 11.3), kidney (RPKM 10.4) and 25 other tissues See more Orthologs mouse all
FBXO3-DT, Official Symbol FBXO3-DTprovided by HGNC Official Full Name FBXO3 divergent transcriptprovided by HGNC Primary source HGNC:HGNC:51147 See related Ensembl:ENSG00000254508 AllianceGenome:HGNC:51147 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBXO3-AS1 Expression Restricted expression toward testis (RPKM 3.7) See more
FBXO30, Official Symbol FBXO30provided by HGNC Official Full Name F-box protein 30provided by HGNC Primary source HGNC:HGNC:15600 See related Ensembl:ENSG00000118496 MIM:609101; AllianceGenome:HGNC:15600 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx30 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 3.5), testis (RPKM 3.3) and 25 other tissues See more Orthologs mouse all
FBXO31, Official Symbol FBXO31provided by HGNC Official Full Name F-box protein 31provided by HGNC Primary source HGNC:HGNC:16510 See related Ensembl:ENSG00000103264 MIM:609102; AllianceGenome:HGNC:16510 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX14; Fbx31; MRT45; FBXO14; pp2386 Summary This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in fat (RPKM 13.6), ovary (RPKM 7.7) and 25 other tissues See more Orthologs mouse all
FBXO32, Official Symbol FBXO32provided by HGNC Official Full Name F-box protein 32provided by HGNC Primary source HGNC:HGNC:16731 See related Ensembl:ENSG00000156804 MIM:606604; AllianceGenome:HGNC:16731 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx32; MAFbx Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] Expression Broad expression in endometrium (RPKM 28.7), heart (RPKM 22.1) and 18 other tissues See more Orthologs mouse all
FBXO33, Official Symbol FBXO33provided by HGNC Official Full Name F-box protein 33provided by HGNC Primary source HGNC:HGNC:19833 See related Ensembl:ENSG00000165355 MIM:609103; AllianceGenome:HGNC:19833 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx33; BMND12; c14_5247 Summary This locus represents an member of the F-box gene family. The encoded protein contains an F-box motif and a domain that might form a structure similar to a leucine-rich repeat found in placental RNAse inhibitor. This locus may be associated with copy number variation of UGT2B17 (GeneID 7367), which has been associated with susceptibility to osteoporosis.[provided by RefSeq, Sep 2010] Expression Ubiquitous expression in bone marrow (RPKM 14.0), testis (RPKM 6.8) and 24 other tissues See more Orthologs mouse all
FBXO34, Official Symbol FBXO34provided by HGNC Official Full Name F-box protein 34provided by HGNC Primary source HGNC:HGNC:20201 See related Ensembl:ENSG00000178974 MIM:609104; AllianceGenome:HGNC:20201 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx34; CGI-301 Summary Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 12.2), esophagus (RPKM 11.1) and 25 other tissues See more Orthologs mouse all
FBXO36, Official Symbol FBXO36provided by HGNC Official Full Name F-box protein 36provided by HGNC Primary source HGNC:HGNC:27020 See related Ensembl:ENSG00000153832 MIM:609105; AllianceGenome:HGNC:27020 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx36 Summary Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Broad expression in thyroid (RPKM 4.9), testis (RPKM 3.7) and 24 other tissues See more Orthologs mouse all
FBXO38, Official Symbol FBXO38provided by HGNC Official Full Name F-box protein 38provided by HGNC Primary source HGNC:HGNC:28844 See related Ensembl:ENSG00000145868 MIM:608533; AllianceGenome:HGNC:28844 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOKA; Fbx38; HMN2D; SP329 Summary This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Expression Ubiquitous expression in testis (RPKM 8.9), prostate (RPKM 8.6) and 25 other tissues See more Orthologs mouse all
FBXO39, Official Symbol FBXO39provided by HGNC Official Full Name F-box protein 39provided by HGNC Primary source HGNC:HGNC:28565 See related Ensembl:ENSG00000177294 MIM:609106; AllianceGenome:HGNC:28565 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT144; Fbx39; FBOX39 Summary Members of the F-box protein family, such as FBXO39, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Restricted expression toward testis (RPKM 12.8) See more Orthologs mouse all
FBXO4, Official Symbol FBXO4provided by HGNC Official Full Name F-box protein 4provided by HGNC Primary source HGNC:HGNC:13583 See related Ensembl:ENSG00000151876 MIM:609090; AllianceGenome:HGNC:13583 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX4 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in thyroid (RPKM 3.2), lymph node (RPKM 2.5) and 25 other tissues See more Orthologs mouse all
FBXO40, Official Symbol FBXO40provided by HGNC Official Full Name F-box protein 40provided by HGNC Primary source HGNC:HGNC:29816 See related Ensembl:ENSG00000163833 MIM:609107; AllianceGenome:HGNC:29816 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX40 Summary Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Restricted expression toward heart (RPKM 38.1) See more Orthologs mouse all
FBXO41, Official Symbol FBXO41provided by HGNC Official Full Name F-box protein 41provided by HGNC Primary source HGNC:HGNC:29409 See related Ensembl:ENSG00000163013 MIM:609108; AllianceGenome:HGNC:29409 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX41 Summary This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014] Expression Biased expression in brain (RPKM 10.6), lymph node (RPKM 3.0) and 13 other tissues See more Orthologs mouse all
FBXO42, Official Symbol FBXO42provided by HGNC Official Full Name F-box protein 42provided by HGNC Primary source HGNC:HGNC:29249 See related Ensembl:ENSG00000037637 MIM:609109; AllianceGenome:HGNC:29249 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JFK; Fbx42 Summary Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010] Expression Ubiquitous expression in skin (RPKM 6.4), fat (RPKM 5.1) and 25 other tissues See more Orthologs mouse all
FBXO43, Official Symbol FBXO43provided by HGNC Official Full Name F-box protein 43provided by HGNC Primary source HGNC:HGNC:28521 See related Ensembl:ENSG00000156509 MIM:609110; AllianceGenome:HGNC:28521 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMI2; ERP1; FBX43; OOMD12; SPGF64; OZEMA12 Summary Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 4.9), lymph node (RPKM 0.6) and 2 other tissues See more Orthologs mouse all
FBXO44, Official Symbol FBXO44provided by HGNC Official Full Name F-box protein 44provided by HGNC Primary source HGNC:HGNC:24847 See related Ensembl:ENSG00000132879 MIM:609111; AllianceGenome:HGNC:24847 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG3; FBX30; FBX6A; Fbx44; Fbxo6a Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015] Expression Ubiquitous expression in brain (RPKM 16.4), adrenal (RPKM 7.6) and 25 other tissues See more Orthologs mouse all
FBXO45, Official Symbol FBXO45provided by HGNC Official Full Name F-box protein 45provided by HGNC Primary source HGNC:HGNC:29148 See related Ensembl:ENSG00000174013 MIM:609112; AllianceGenome:HGNC:29148 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx45 Summary Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Jan 2011] Expression Ubiquitous expression in brain (RPKM 6.3), testis (RPKM 6.3) and 25 other tissues See more Orthologs mouse all
FBXO46, Official Symbol FBXO46provided by HGNC Official Full Name F-box protein 46provided by HGNC Primary source HGNC:HGNC:25069 See related Ensembl:ENSG00000177051 MIM:609117; AllianceGenome:HGNC:25069 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx46; FBXO34L; 20D7-FC4 Summary Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in spleen (RPKM 4.8), testis (RPKM 4.4) and 25 other tissues See more Orthologs mouse all
FBXO47, Official Symbol FBXO47provided by HGNC Official Full Name F-box protein 47provided by HGNC Primary source HGNC:HGNC:31969 See related Ensembl:ENSG00000204952 MIM:609498; AllianceGenome:HGNC:31969 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 2.5) See more Orthologs mouse all
FBXO48, Official Symbol FBXO48provided by HGNC Official Full Name F-box protein 48provided by HGNC Primary source HGNC:HGNC:33857 See related Ensembl:ENSG00000204923 AllianceGenome:HGNC:33857 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 1.2), duodenum (RPKM 1.0) and 25 other tissues See more Orthologs mouse all
FBXO5, Official Symbol FBXO5provided by HGNC Official Full Name F-box protein 5provided by HGNC Primary source HGNC:HGNC:13584 See related Ensembl:ENSG00000112029 MIM:606013; AllianceGenome:HGNC:13584 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMI1; FBX5; Fbxo31 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008] Expression Broad expression in bone marrow (RPKM 14.0), lymph node (RPKM 6.9) and 22 other tissues See more Orthologs mouse all
FBXO6, Official Symbol FBXO6provided by HGNC Official Full Name F-box protein 6provided by HGNC Primary source HGNC:HGNC:13585 See related Ensembl:ENSG00000116663 MIM:605647; AllianceGenome:HGNC:13585 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG2; FBS2; FBX6; Fbx6b Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 5.5), appendix (RPKM 4.6) and 25 other tissues See more Orthologs all
FBXO7, Official Symbol FBXO7provided by HGNC Official Full Name F-box protein 7provided by HGNC Primary source HGNC:HGNC:13586 See related Ensembl:ENSG00000100225 MIM:605648; AllianceGenome:HGNC:13586 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX; FBX7; PKPS; FBX07; PARK15 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 94.0), thyroid (RPKM 68.7) and 25 other tissues See more Orthologs mouse all
FBXO8, Official Symbol FBXO8provided by HGNC Official Full Name F-box protein 8provided by HGNC Primary source HGNC:HGNC:13587 See related Ensembl:ENSG00000164117 MIM:605649; AllianceGenome:HGNC:13587 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBS; DC10; FBX8 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in placenta (RPKM 13.8), thyroid (RPKM 12.0) and 25 other tissues See more Orthologs mouse all
FBXO9, Official Symbol FBXO9provided by HGNC Official Full Name F-box protein 9provided by HGNC Primary source HGNC:HGNC:13588 See related Ensembl:ENSG00000112146 MIM:609091; AllianceGenome:HGNC:13588 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX9; VCIA1; NY-REN-57; dJ341E18.2 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 15.5), bone marrow (RPKM 13.7) and 25 other tissues See more Orthologs mouse all
FBXW10, Official Symbol FBXW10provided by HGNC Official Full Name F-box and WD repeat domain containing 10provided by HGNC Primary source HGNC:HGNC:1211 See related Ensembl:ENSG00000171931 MIM:611679; AllianceGenome:HGNC:1211 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HREP; Fbw10; SM25H2; SM2SH2 Summary Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 6.8) and esophagus (RPKM 0.4) See more Orthologs mouse all
FBXW11, Official Symbol FBXW11provided by HGNC Official Full Name F-box and WD repeat domain containing 11provided by HGNC Primary source HGNC:HGNC:13607 See related Ensembl:ENSG00000072803 MIM:605651; AllianceGenome:HGNC:13607 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B; NEDJED Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 22.1), heart (RPKM 11.8) and 25 other tissues See more Orthologs mouse all
FBXW11P1, Official Symbol FBXW11P1provided by HGNC Official Full Name F-box and WD repeat domain containing 11 pseudogene 1provided by HGNC Primary source HGNC:HGNC:1145 See related Ensembl:ENSG00000230870 AllianceGenome:HGNC:1145 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTRC2P; FBXW1BP; FBXW1BP1
FBXW12, Official Symbol FBXW12provided by HGNC Official Full Name F-box and WD repeat domain containing 12provided by HGNC Primary source HGNC:HGNC:20729 See related Ensembl:ENSG00000164049 MIM:609075; AllianceGenome:HGNC:20729 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBW12; FBXO12; FBXO35 Summary Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Low expression observed in reference dataset See more Orthologs all
FBXW2, Official Symbol FBXW2provided by HGNC Official Full Name F-box and WD repeat domain containing 2provided by HGNC Primary source HGNC:HGNC:13608 See related Ensembl:ENSG00000119402 MIM:609071; AllianceGenome:HGNC:13608 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Md6; FBW2; Fwd2 Summary F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lung (RPKM 8.4), thyroid (RPKM 8.1) and 25 other tissues See more Orthologs mouse all
FBXW4, Official Symbol FBXW4provided by HGNC Official Full Name F-box and WD repeat domain containing 4provided by HGNC Primary source HGNC:HGNC:10847 See related Ensembl:ENSG00000107829 MIM:608071; AllianceGenome:HGNC:10847 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAC; FBW4; FBWD4; SHFM3; SHSF3 Summary This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 17.7), lung (RPKM 17.4) and 25 other tissues See more Orthologs mouse all
FBXW4P1, Official Symbol FBXW4P1provided by HGNC Official Full Name F-box and WD repeat domain containing 4 pseudogene 1provided by HGNC Primary source HGNC:HGNC:13609 See related Ensembl:ENSG00000230701 AllianceGenome:HGNC:13609 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBW3; FBXW3; SHFM3P1