psui3905/ncbi_genes_summary huggingface dataset:
KIAA1217, Official Symbol KIAA1217provided by HGNC Official Full Name KIAA1217provided by HGNC Primary source HGNC:HGNC:25428 See related Ensembl:ENSG00000120549 MIM:617367; AllianceGenome:HGNC:25428 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SKT; ETL4 Summary Predicted to be involved in embryonic skeletal system development. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 10.6), thyroid (RPKM 9.4) and 24 other tissues See more Orthologs mouse all
KIAA1328, Official Symbol KIAA1328provided by HGNC Official Full Name KIAA1328provided by HGNC Primary source HGNC:HGNC:29248 See related Ensembl:ENSG00000150477 MIM:616480; AllianceGenome:HGNC:29248 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in ovary (RPKM 1.6), testis (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
KIAA1549, Official Symbol KIAA1549provided by HGNC Official Full Name KIAA1549provided by HGNC Primary source HGNC:HGNC:22219 See related Ensembl:ENSG00000122778 MIM:613344; AllianceGenome:HGNC:22219 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP86 Summary The protein encoded by this gene belongs to the UPF0606 family. This gene has been found to be fused to the BRAF oncogene in many cases of pilocytic astrocytoma. The fusion results from 2Mb tandem duplications at 7q34. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] Expression Broad expression in brain (RPKM 3.0), kidney (RPKM 2.6) and 21 other tissues See more Orthologs mouse all
KIAA1549L, Official Symbol KIAA1549Lprovided by HGNC Official Full Name KIAA1549 likeprovided by HGNC Primary source HGNC:HGNC:24836 See related Ensembl:ENSG00000110427 MIM:612297; AllianceGenome:HGNC:24836 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2; C11orf41; C11orf69 Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 13.2) and skin (RPKM 0.8) See more Orthologs mouse all
KIAA1586, Official Symbol KIAA1586provided by HGNC Official Full Name KIAA1586provided by HGNC Primary source HGNC:HGNC:21360 See related Ensembl:ENSG00000168116 AllianceGenome:HGNC:21360 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables SUMO ligase activity. Involved in protein sumoylation. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 5.5), placenta (RPKM 5.2) and 25 other tissues See more Orthologs all
KIAA1614, Official Symbol KIAA1614provided by HGNC Official Full Name KIAA1614provided by HGNC Primary source HGNC:HGNC:29327 See related Ensembl:ENSG00000135835 AllianceGenome:HGNC:29327 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable protein kinase C binding activity. Predicted to be involved in centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 1.6), ovary (RPKM 1.5) and 22 other tissues See more Orthologs mouse all
KIAA1614-AS1, Official Symbol KIAA1614-AS1provided by HGNC Official Full Name KIAA1614 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:50644 See related Ensembl:ENSG00000232586 AllianceGenome:HGNC:50644 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
KIAA1671, Official Symbol KIAA1671provided by HGNC Official Full Name KIAA1671provided by HGNC Primary source HGNC:HGNC:29345 See related Ensembl:ENSG00000197077 AllianceGenome:HGNC:29345 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in thyroid (RPKM 12.1), esophagus (RPKM 8.5) and 24 other tissues See more Orthologs mouse all
KIAA1671-AS1, Official Symbol KIAA1671-AS1provided by HGNC Official Full Name KIAA1671 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41238 See related Ensembl:ENSG00000203280 AllianceGenome:HGNC:41238 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in thyroid (RPKM 2.4), liver (RPKM 1.6) and 19 other tissues See more
KIAA1755, Official Symbol KIAA1755provided by HGNC Official Full Name KIAA1755provided by HGNC Primary source HGNC:HGNC:29372 See related Ensembl:ENSG00000149633 AllianceGenome:HGNC:29372 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as quo Expression Broad expression in brain (RPKM 4.2), gall bladder (RPKM 3.0) and 20 other tissues See more Orthologs mouse all
KIAA1958, Official Symbol KIAA1958provided by HGNC Official Full Name KIAA1958provided by HGNC Primary source HGNC:HGNC:23427 See related Ensembl:ENSG00000165185 MIM:617390; AllianceGenome:HGNC:23427 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Broad expression in ovary (RPKM 2.3), adrenal (RPKM 2.3) and 25 other tissues See more Orthologs mouse all
KIAA2012, Official Symbol KIAA2012provided by HGNC Official Full Name KIAA2012provided by HGNC Primary source HGNC:HGNC:51250 See related Ensembl:ENSG00000182329 AllianceGenome:HGNC:51250 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more Orthologs mouse all
KIAA2012-AS1, Official Symbol KIAA2012-AS1provided by HGNC Official Full Name KIAA2012 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41164 See related Ensembl:ENSG00000222035 AllianceGenome:HGNC:41164 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Restricted expression toward testis (RPKM 3.7) See more
KIAA2013, Official Symbol KIAA2013provided by HGNC Official Full Name KIAA2013provided by HGNC Primary source HGNC:HGNC:28513 See related Ensembl:ENSG00000116685 AllianceGenome:HGNC:28513 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 28.0), small intestine (RPKM 27.3) and 25 other tissues See more Orthologs mouse all
KIAA2026, Official Symbol KIAA2026provided by HGNC Official Full Name KIAA2026provided by HGNC Primary source HGNC:HGNC:23378 See related Ensembl:ENSG00000183354 AllianceGenome:HGNC:23378 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in testis (RPKM 4.2), thyroid (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
KIDINS220, Official Symbol KIDINS220provided by HGNC Official Full Name kinase D interacting substrate 220provided by HGNC Primary source HGNC:HGNC:29508 See related Ensembl:ENSG00000134313 MIM:615759; AllianceGenome:HGNC:29508 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARMS; SINO; VENARG Summary This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in brain (RPKM 28.9), ovary (RPKM 19.1) and 25 other tissues See more Orthologs mouse all
KIF11, Official Symbol KIF11provided by HGNC Official Full Name kinesin family member 11provided by HGNC Primary source HGNC:HGNC:6388 See related Ensembl:ENSG00000138160 MIM:148760; AllianceGenome:HGNC:6388 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EG5; HKSP; KNSL1; MCLMR; TRIP5 Summary This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 9.9), bone marrow (RPKM 8.6) and 18 other tissues See more Orthologs mouse all
KIF12, Official Symbol KIF12provided by HGNC Official Full Name kinesin family member 12provided by HGNC Primary source HGNC:HGNC:21495 See related Ensembl:ENSG00000136883 MIM:611278; AllianceGenome:HGNC:21495 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFIC8 Summary This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance. [provided by RefSeq, Jul 2016] Expression Biased expression in kidney (RPKM 28.1), gall bladder (RPKM 9.6) and 9 other tissues See more Orthologs mouse all
KIF13A, Official Symbol KIF13Aprovided by HGNC Official Full Name kinesin family member 13Aprovided by HGNC Primary source HGNC:HGNC:14566 See related Ensembl:ENSG00000137177 MIM:605433; AllianceGenome:HGNC:14566 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RBKIN; bA500C11.2 Summary This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in heart (RPKM 12.6), thyroid (RPKM 10.1) and 25 other tissues See more Orthologs mouse all
KIF13B, Official Symbol KIF13Bprovided by HGNC Official Full Name kinesin family member 13Bprovided by HGNC Primary source HGNC:HGNC:14405 See related Ensembl:ENSG00000197892 MIM:607350; AllianceGenome:HGNC:14405 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAKIN Summary Enables 14-3-3 protein binding activity and protein kinase binding activity. Involved in regulation of axonogenesis. Located in axon and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 15.2), colon (RPKM 14.6) and 25 other tissues See more Orthologs mouse all
KIF14, Official Symbol KIF14provided by HGNC Official Full Name kinesin family member 14provided by HGNC Primary source HGNC:HGNC:19181 See related Ensembl:ENSG00000118193 MIM:611279; AllianceGenome:HGNC:19181 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKS12; MCPH20 Summary This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] Expression Broad expression in bone marrow (RPKM 2.3), lymph node (RPKM 1.7) and 14 other tissues See more Orthologs mouse all
KIF15, Official Symbol KIF15provided by HGNC Official Full Name kinesin family member 15provided by HGNC Primary source HGNC:HGNC:17273 See related Ensembl:ENSG00000163808 MIM:617569; AllianceGenome:HGNC:17273 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLP2; HKLP2; KNSL7; BRDCS2; NY-BR-62 Summary Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in microtubule-based movement. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 8.0), bone marrow (RPKM 4.1) and 13 other tissues See more Orthologs mouse all
KIF16B, Official Symbol KIF16Bprovided by HGNC Official Full Name kinesin family member 16Bprovided by HGNC Primary source HGNC:HGNC:15869 See related Ensembl:ENSG00000089177 MIM:618171; AllianceGenome:HGNC:15869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SNX23; C20orf23; KISC20ORF Summary The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in adrenal (RPKM 10.5), colon (RPKM 7.0) and 24 other tissues See more Orthologs mouse all
KIF17, Official Symbol KIF17provided by HGNC Official Full Name kinesin family member 17provided by HGNC Primary source HGNC:HGNC:19167 See related Ensembl:ENSG00000117245 MIM:605037; AllianceGenome:HGNC:19167 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIF3X; KLP-2; OSM-3; KIF17B Summary Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cell projection organization. Predicted to act upstream of or within microtubule-based process; protein-containing complex localization; and vesicle-mediated transport. Predicted to be located in microtubule cytoskeleton. Predicted to be part of intraciliary transport particle B and kinesin complex. Predicted to be active in cilium; microtubule cytoskeleton; and neuron projection. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 11.7), spleen (RPKM 7.5) and 6 other tissues See more Orthologs mouse all
KIF18A, Official Symbol KIF18Aprovided by HGNC Official Full Name kinesin family member 18Aprovided by HGNC Primary source HGNC:HGNC:29441 See related Ensembl:ENSG00000121621 MIM:611271; AllianceGenome:HGNC:29441 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPP1R99; MS-KIF18A Summary KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008] Expression Biased expression in testis (RPKM 7.1), bone marrow (RPKM 2.7) and 11 other tissues See more Orthologs mouse all
KIF18B, Official Symbol KIF18Bprovided by HGNC Official Full Name kinesin family member 18Bprovided by HGNC Primary source HGNC:HGNC:27102 See related Ensembl:ENSG00000186185 MIM:614570; AllianceGenome:HGNC:27102 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables cytoskeletal motor activity and kinesin binding activity. Involved in microtubule depolymerization; mitotic cell cycle; and regulation of cell division. Located in cytosol; microtubule; and nuclear body. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 3.6), lymph node (RPKM 2.4) and 14 other tissues See more Orthologs mouse all
KIF19, Official Symbol KIF19provided by HGNC Official Full Name kinesin family member 19provided by HGNC Primary source HGNC:HGNC:26735 See related Ensembl:ENSG00000196169 MIM:619610; AllianceGenome:HGNC:26735 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIF19A Summary Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in axonemal microtubule depolymerization; microtubule-based movement; and plus-end specific microtubule depolymerization. Predicted to be located in cilium. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 3.3), duodenum (RPKM 1.5) and 14 other tissues See more Orthologs mouse all
KIF1A, Official Symbol KIF1Aprovided by HGNC Official Full Name kinesin family member 1Aprovided by HGNC Primary source HGNC:HGNC:888 See related Ensembl:ENSG00000130294 MIM:601255; AllianceGenome:HGNC:888 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATSV; MRD9; HSN2C; SPG30; UNC104; C2orf20; NESCAVS Summary The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] Expression Biased expression in brain (RPKM 88.6), adrenal (RPKM 8.2) and 1 other tissue See more Orthologs mouse all
KIF1B, Official Symbol KIF1Bprovided by HGNC Official Full Name kinesin family member 1Bprovided by HGNC Primary source HGNC:HGNC:16636 See related Ensembl:ENSG00000054523 MIM:605995; AllianceGenome:HGNC:16636 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1 Summary Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in chemical synaptic transmission; dense core granule cytoskeletal transport; and vesicle-mediated transport. Predicted to act upstream of or within mitochondrion transport along microtubule. Predicted to be located in cytoplasmic vesicle membrane and neuron projection. Predicted to be part of kinesin complex. Predicted to be active in several cellular components, including axon; dendrite; and microtubule. Implicated in Charcot-Marie-Tooth disease type 2A1; carcinoma (multiple); multiple sclerosis; neuroblastoma; and pheochromocytoma. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 28.3), testis (RPKM 7.8) and 23 other tissues See more Orthologs mouse all
KIF1C, Official Symbol KIF1Cprovided by HGNC Official Full Name kinesin family member 1Cprovided by HGNC Primary source HGNC:HGNC:6317 See related Ensembl:ENSG00000129250 MIM:603060; AllianceGenome:HGNC:6317 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAX2; LTXS1; SATX2; SPAX2; SPG58 Summary The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014] Expression Ubiquitous expression in heart (RPKM 51.8), fat (RPKM 28.5) and 24 other tissues See more Orthologs mouse all
KIF1C-AS1, Official Symbol KIF1C-AS1provided by HGNC Official Full Name KIF1C antisense RNA 1provided by HGNC Primary source HGNC:HGNC:40324 See related Ensembl:ENSG00000227495 AllianceGenome:HGNC:40324 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Ubiquitous expression in heart (RPKM 20.2), esophagus (RPKM 12.0) and 24 other tissues See more
KIF20A, Official Symbol KIF20Aprovided by HGNC Official Full Name kinesin family member 20Aprovided by HGNC Primary source HGNC:HGNC:9787 See related Ensembl:ENSG00000112984 MIM:605664; AllianceGenome:HGNC:9787 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RCM6; MKLP2; RAB6KIFL Summary Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 7.6), bone marrow (RPKM 5.2) and 14 other tissues See more Orthologs mouse all
KIF20B, Official Symbol KIF20Bprovided by HGNC Official Full Name kinesin family member 20Bprovided by HGNC Primary source HGNC:HGNC:7212 See related Ensembl:ENSG00000138182 MIM:605498; AllianceGenome:HGNC:7212 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT90; MPP1; KRMP1; MPP-1; MPHOSPH1 Summary Enables several functions, including WW domain binding activity; plus-end-directed microtubule motor activity; and protein homodimerization activity. Involved in positive regulation of cell population proliferation and positive regulation of cytokinesis. Located in several cellular components, including microtubule cytoskeleton; midbody; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 5.3), lymph node (RPKM 5.3) and 24 other tissues See more Orthologs mouse all
KIF21A, Official Symbol KIF21Aprovided by HGNC Official Full Name kinesin family member 21Aprovided by HGNC Primary source HGNC:HGNC:19349 See related Ensembl:ENSG00000139116 MIM:608283; AllianceGenome:HGNC:19349 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEOM1; CFEOM1; FEOM3A Summary This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010] Expression Broad expression in brain (RPKM 25.3), kidney (RPKM 9.6) and 22 other tissues See more Orthologs mouse all
KIF21B, Official Symbol KIF21Bprovided by HGNC Official Full Name kinesin family member 21Bprovided by HGNC Primary source HGNC:HGNC:29442 See related Ensembl:ENSG00000116852 MIM:608322; AllianceGenome:HGNC:29442 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] Expression Biased expression in bone marrow (RPKM 12.6), brain (RPKM 10.5) and 11 other tissues See more Orthologs mouse all
KIF22, Official Symbol KIF22provided by HGNC Official Full Name kinesin family member 22provided by HGNC Primary source HGNC:HGNC:6391 See related Ensembl:ENSG00000079616 MIM:603213; AllianceGenome:HGNC:6391 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KID; OBP; KNSL4; OBP-1; OBP-2; SEMDJL2; A-328A3.2 Summary The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Expression Broad expression in bone marrow (RPKM 24.9), testis (RPKM 13.3) and 24 other tissues See more Orthologs mouse all
KIF23, Official Symbol KIF23provided by HGNC Official Full Name kinesin family member 23provided by HGNC Primary source HGNC:HGNC:6392 See related Ensembl:ENSG00000137807 MIM:605064; AllianceGenome:HGNC:6392 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDA3; CHO1; CDAN3; KNSL5; MKLP1; CDAIII; CDAN3A; MKLP-1 Summary The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in bone marrow (RPKM 9.3), testis (RPKM 8.0) and 17 other tissues See more Orthologs mouse all
KIF24, Official Symbol KIF24provided by HGNC Official Full Name kinesin family member 24provided by HGNC Primary source HGNC:HGNC:19916 See related Ensembl:ENSG00000186638 MIM:613747; AllianceGenome:HGNC:19916 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C9orf48; bA571F15.4 Summary This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017] Expression Broad expression in testis (RPKM 7.5), bone marrow (RPKM 4.2) and 25 other tissues See more Orthologs mouse all
KIF25, Official Symbol KIF25provided by HGNC Official Full Name kinesin family member 25provided by HGNC Primary source HGNC:HGNC:6390 See related Ensembl:ENSG00000125337 MIM:603815; AllianceGenome:HGNC:6390 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KNSL3 Summary The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 4.7) and placenta (RPKM 0.3) See more Orthologs all
KIF25-AS1, Official Symbol KIF25-AS1provided by HGNC Official Full Name KIF25 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:20953 See related Ensembl:ENSG00000229921 AllianceGenome:HGNC:20953 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf54; HGC6.1.1; NCRNA00300 Expression Low expression observed in reference dataset See more
KIF26A, Official Symbol KIF26Aprovided by HGNC Official Full Name kinesin family member 26Aprovided by HGNC Primary source HGNC:HGNC:20226 See related Ensembl:ENSG00000066735 MIM:613231; AllianceGenome:HGNC:20226 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDCBM11 Summary Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in enteric nervous system development; negative regulation of signal transduction; and regulation of cell growth by extracellular stimulus. Predicted to be located in cytosol. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 3.9), spleen (RPKM 2.2) and 20 other tissues See more Orthologs mouse all
KIF26B, Official Symbol KIF26Bprovided by HGNC Official Full Name kinesin family member 26Bprovided by HGNC Primary source HGNC:HGNC:25484 See related Ensembl:ENSG00000162849 MIM:614026; AllianceGenome:HGNC:25484 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is an intracellular motor protein thought to transport organelles along microtubules. The encoded protein is required for kidney development. Elevated levels of this protein have been found in some breast and colorectal cancers. [provided by RefSeq, Mar 2017] Expression Broad expression in placenta (RPKM 1.6), endometrium (RPKM 0.9) and 19 other tissues See more Orthologs mouse all
KIF26B-AS1, Official Symbol KIF26B-AS1provided by HGNC Official Full Name KIF26B antisense RNA 1provided by HGNC Primary source HGNC:HGNC:41098 See related Ensembl:ENSG00000232192 AllianceGenome:HGNC:41098 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
KIF27, Official Symbol KIF27provided by HGNC Official Full Name kinesin family member 27provided by HGNC Primary source HGNC:HGNC:18632 See related Ensembl:ENSG00000165115 MIM:611253; AllianceGenome:HGNC:18632 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is a member of the KIF27 (kinesin 4) sub-family of the mammalian kinesin family. The gene is an ortholog of the Drosophila Cos2 gene, which plays an important role in the Hedgehog signaling pathway. The encoded protein contains an N-terminal motor domain which includes nucleotide-binding and microtubule-interacting regions, a stalk domain containing a predicted coiled coil motif and a C-terminal tail domain. Alternatively spliced transcript variants have been observed for this gene. Pseudogenes associated with this gene are located on chromosome 9. [provided by RefSeq, Dec 2012] Expression Broad expression in testis (RPKM 7.5), thyroid (RPKM 3.1) and 21 other tissues See more Orthologs mouse all
KIF28P, Official Symbol KIF28Pprovided by HGNC Official Full Name kinesin family member 28, pseudogeneprovided by HGNC Primary source HGNC:HGNC:49205 See related AllianceGenome:HGNC:49205 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLP-6 Summary Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in mitochondrion organization and organelle transport along microtubule. Predicted to be located in mitochondrial membrane. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all
KIF2A, Official Symbol KIF2Aprovided by HGNC Official Full Name kinesin family member 2Aprovided by HGNC Primary source HGNC:HGNC:6318 See related Ensembl:ENSG00000068796 MIM:602591; AllianceGenome:HGNC:6318 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HK2; KIF2; CDCBM3 Summary The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Expression Broad expression in testis (RPKM 17.8), brain (RPKM 16.2) and 24 other tissues See more Orthologs mouse all
KIF2B, Official Symbol KIF2Bprovided by HGNC Official Full Name kinesin family member 2Bprovided by HGNC Primary source HGNC:HGNC:29443 See related Ensembl:ENSG00000141200 MIM:615142; AllianceGenome:HGNC:29443 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable microtubule binding activity and microtubule motor activity. Involved in metaphase plate congression; microtubule depolymerization; and regulation of chromosome segregation. Located in intercellular bridge; mitotic spindle; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all
KIF2C, Official Symbol KIF2Cprovided by HGNC Official Full Name kinesin family member 2Cprovided by HGNC Primary source HGNC:HGNC:6393 See related Ensembl:ENSG00000142945 MIM:604538; AllianceGenome:HGNC:6393 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCAK; CT139; KNSL6 Summary This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Biased expression in testis (RPKM 39.1), bone marrow (RPKM 9.5) and 6 other tissues See more Orthologs mouse all
KIF3A, Official Symbol KIF3Aprovided by HGNC Official Full Name kinesin family member 3Aprovided by HGNC Primary source HGNC:HGNC:6319 See related Ensembl:ENSG00000131437 MIM:604683; AllianceGenome:HGNC:6319 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLA10; KLP-20 Summary Enables protein phosphatase binding activity; small GTPase binding activity; and spectrin binding activity. Involved in protein localization to cell junction and protein transport. Located in centriole and centrosome. Part of kinesin II complex. Colocalizes with spindle microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 20.7), testis (RPKM 8.8) and 19 other tissues See more Orthologs mouse all
KIF3AP1, Official Symbol KIF3AP1provided by HGNC Official Full Name kinesin family member 3A pseudogene 1provided by HGNC Primary source HGNC:HGNC:52811 See related Ensembl:ENSG00000235836 AllianceGenome:HGNC:52811 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
KIF3B, Official Symbol KIF3Bprovided by HGNC Official Full Name kinesin family member 3Bprovided by HGNC Primary source HGNC:HGNC:6320 See related Ensembl:ENSG00000101350 MIM:603754; AllianceGenome:HGNC:6320 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLA8; RP89; HH0048; KLP-11 Summary The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 22.2), kidney (RPKM 21.4) and 25 other tissues See more Orthologs mouse all
KIF3C, Official Symbol KIF3Cprovided by HGNC Official Full Name kinesin family member 3Cprovided by HGNC Primary source HGNC:HGNC:6321 See related Ensembl:ENSG00000084731 MIM:602845; AllianceGenome:HGNC:6321 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to act upstream of or within organelle transport along microtubule. Predicted to be located in microtubule cytoskeleton; neuronal cell body; and neuronal ribonucleoprotein granule. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 57.3), adrenal (RPKM 4.3) and 1 other tissue See more Orthologs mouse all
KIF4A, Official Symbol KIF4Aprovided by HGNC Official Full Name kinesin family member 4Aprovided by HGNC Primary source HGNC:HGNC:13339 See related Ensembl:ENSG00000090889 MIM:300521; AllianceGenome:HGNC:13339 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIF4; KIF4G1; MRX100; XLID100 Summary This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010] Expression Broad expression in bone marrow (RPKM 4.3), lymph node (RPKM 2.9) and 14 other tissues See more Orthologs mouse all
KIF4B, Official Symbol KIF4Bprovided by HGNC Official Full Name kinesin family member 4Bprovided by HGNC Primary source HGNC:HGNC:6322 See related Ensembl:ENSG00000226650 MIM:609184; AllianceGenome:HGNC:6322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is an intronless retrocopy of kinesin family member 4A. The protein encoded by this gene is a microtubule-based motor protein that plays vital roles in anaphase spindle dynamics and cytokinesis. [provided by RefSeq, Jul 2016] Orthologs all
KIF5A, Official Symbol KIF5Aprovided by HGNC Official Full Name kinesin family member 5Aprovided by HGNC Primary source HGNC:HGNC:6323 See related Ensembl:ENSG00000155980 MIM:602821; AllianceGenome:HGNC:6323 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NKHC; ALS25; MY050; NEIMY; SPG10; D12S1889 Summary This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 141.3) and adrenal (RPKM 5.1) See more Orthologs mouse all