psui3905/ncbi_genes_summary huggingface dataset:
VPS53, Official Symbol VPS53provided by HGNC Official Full Name VPS53 subunit of GARP complexprovided by HGNC Primary source HGNC:HGNC:25608 See related Ensembl:ENSG00000141252 MIM:615850; AllianceGenome:HGNC:25608 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCCS1; PCH2E; hVps53L; pp13624 Summary Involved in endocytic recycling and retrograde transport, endosome to Golgi. Acts upstream of or within lysosomal transport. Located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and recycling endosome. Part of EARP complex and GARP complex. Implicated in pontocerebellar hypoplasia type 2E. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.1), brain (RPKM 5.4) and 25 other tissues See more Orthologs mouse all
VPS54, Official Symbol VPS54provided by HGNC Official Full Name VPS54 subunit of GARP complexprovided by HGNC Primary source HGNC:HGNC:18652 See related Ensembl:ENSG00000143952 MIM:614633; AllianceGenome:HGNC:18652 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WR; HCC8; SLP-8p; VPS54L; hVps54L; PPP1R164 Summary This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 11.2), prostate (RPKM 10.0) and 25 other tissues See more Orthologs mouse all
VPS72, Official Symbol VPS72provided by HGNC Official Full Name vacuolar protein sorting 72 homologprovided by HGNC Primary source HGNC:HGNC:11644 See related Ensembl:ENSG00000163159 MIM:600607; AllianceGenome:HGNC:11644 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YL1; CFL1; Swc2; YL-1; TCFL1 Summary The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in brain (RPKM 14.7), prostate (RPKM 14.0) and 25 other tissues See more Orthologs mouse all
VPS8, Official Symbol VPS8provided by HGNC Official Full Name VPS8 subunit of CORVET complexprovided by HGNC Primary source HGNC:HGNC:29122 See related Ensembl:ENSG00000156931 MIM:618366; AllianceGenome:HGNC:29122 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA0804 Summary Predicted to enable metal ion binding activity. Involved in endosomal vesicle fusion. Located in early endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.2), brain (RPKM 7.7) and 25 other tissues See more Orthologs mouse all
VPS9D1, Official Symbol VPS9D1provided by HGNC Official Full Name VPS9 domain containing 1provided by HGNC Primary source HGNC:HGNC:13526 See related Ensembl:ENSG00000075399 MIM:619292; AllianceGenome:HGNC:13526 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATPBL; ATP-BL; C16orf7 Summary Enables identical protein binding activity. Predicted to be involved in ATP synthesis coupled proton transport. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 5.5), appendix (RPKM 5.3) and 25 other tissues See more Orthologs mouse all
VPS9D1-AS1, Official Symbol VPS9D1-AS1provided by HGNC Official Full Name VPS9D1 antisense RNA 1provided by HGNC Primary source HGNC:HGNC:48915 See related Ensembl:ENSG00000261373 AllianceGenome:HGNC:48915 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYU Expression Ubiquitous expression in appendix (RPKM 4.0), brain (RPKM 3.4) and 25 other tissues See more
VRK1, Official Symbol VRK1provided by HGNC Official Full Name VRK serine/threonine kinase 1provided by HGNC Primary source HGNC:HGNC:12718 See related Ensembl:ENSG00000100749 MIM:602168; AllianceGenome:HGNC:12718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCH1; PCH1A Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 15.9), testis (RPKM 12.9) and 23 other tissues See more Orthologs mouse all
VRK2, Official Symbol VRK2provided by HGNC Official Full Name VRK serine/threonine kinase 2provided by HGNC Primary source HGNC:HGNC:12719 See related Ensembl:ENSG00000028116 MIM:602169; AllianceGenome:HGNC:12719 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014] Expression Ubiquitous expression in adrenal (RPKM 6.3), appendix (RPKM 5.7) and 25 other tissues See more Orthologs mouse all
VRK3, Official Symbol VRK3provided by HGNC Official Full Name VRK serine/threonine kinase 3provided by HGNC Primary source HGNC:HGNC:18996 See related Ensembl:ENSG00000105053 MIM:619771; AllianceGenome:HGNC:18996 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 36.5), small intestine (RPKM 9.1) and 24 other tissues See more Orthologs mouse all
VRTN, Official Symbol VRTNprovided by HGNC Official Full Name vertebrae development associatedprovided by HGNC Primary source HGNC:HGNC:20223 See related Ensembl:ENSG00000133980 MIM:620468; AllianceGenome:HGNC:20223 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as vertnin; C14orf115 Summary Predicted to enable sequence-specific DNA binding activity and transposase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
VSIG1, Official Symbol VSIG1provided by HGNC Official Full Name V-set and immunoglobulin domain containing 1provided by HGNC Primary source HGNC:HGNC:28675 See related Ensembl:ENSG00000101842 MIM:300620; AllianceGenome:HGNC:28675 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPA34; dJ889N15.1; 1700062D20Rik Summary This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] Expression Biased expression in stomach (RPKM 88.2), testis (RPKM 34.6) and 1 other tissue See more Orthologs mouse all
VSIG10, Official Symbol VSIG10provided by HGNC Official Full Name V-set and immunoglobulin domain containing 10provided by HGNC Primary source HGNC:HGNC:26078 See related Ensembl:ENSG00000176834 AllianceGenome:HGNC:26078 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in small intestine (RPKM 12.6), colon (RPKM 8.8) and 24 other tissues See more Orthologs mouse all
VSIG10L, Official Symbol VSIG10Lprovided by HGNC Official Full Name V-set and immunoglobulin domain containing 10 likeprovided by HGNC Primary source HGNC:HGNC:27111 See related Ensembl:ENSG00000186806 MIM:617740; AllianceGenome:HGNC:27111 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in esophagus (RPKM 25.9), salivary gland (RPKM 8.6) and 4 other tissues See more Orthologs mouse all
VSIG10L2, Official Symbol VSIG10L2provided by HGNC Official Full Name V-set and immunoglobulin domain containing 10 like 2provided by HGNC Primary source HGNC:HGNC:27879 See related Ensembl:ENSG00000283703 AllianceGenome:HGNC:27879 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 3.2), spleen (RPKM 0.6) and 1 other tissue See more Orthologs mouse all
VSIG2, Official Symbol VSIG2provided by HGNC Official Full Name V-set and immunoglobulin domain containing 2provided by HGNC Primary source HGNC:HGNC:17149 See related Ensembl:ENSG00000019102 MIM:606011; AllianceGenome:HGNC:17149 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTH; CTXL; 2210413P10Rik Summary Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in stomach (RPKM 210.7), colon (RPKM 56.0) and 6 other tissues See more Orthologs mouse all
VSIG4, Official Symbol VSIG4provided by HGNC Official Full Name V-set and immunoglobulin domain containing 4provided by HGNC Primary source HGNC:HGNC:17032 See related Ensembl:ENSG00000155659 MIM:300353; AllianceGenome:HGNC:17032 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRIg; Z39IG Summary This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Broad expression in placenta (RPKM 50.4), lung (RPKM 39.9) and 19 other tissues See more Orthologs mouse all
VSIG8, Official Symbol VSIG8provided by HGNC Official Full Name V-set and immunoglobulin domain containing 8provided by HGNC Primary source HGNC:HGNC:32063 See related Ensembl:ENSG00000243284 AllianceGenome:HGNC:32063 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables RNA binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 5.5), kidney (RPKM 1.8) and 4 other tissues See more Orthologs mouse all
VSIR, Official Symbol VSIRprovided by HGNC Official Full Name V-set immunoregulatory receptorprovided by HGNC Primary source HGNC:HGNC:30085 See related Ensembl:ENSG00000107738 MIM:615608; AllianceGenome:HGNC:30085 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7H5; GI24; B7-H5; Dies1; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha Summary Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 39.2), bone marrow (RPKM 38.8) and 23 other tissues See more Orthologs mouse all
VSNL1, Official Symbol VSNL1provided by HGNC Official Full Name visinin like 1provided by HGNC Primary source HGNC:HGNC:12722 See related Ensembl:ENSG00000163032 MIM:600817; AllianceGenome:HGNC:12722 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLP3; VILIP; HPCAL3; HUVISL1; VILIP-1 Summary This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 206.9), esophagus (RPKM 16.5) and 2 other tissues See more Orthologs mouse all
VSTM1, Official Symbol VSTM1provided by HGNC Official Full Name V-set and transmembrane domain containing 1provided by HGNC Primary source HGNC:HGNC:29455 See related Ensembl:ENSG00000189068 MIM:616804; AllianceGenome:HGNC:29455 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIRL1; SIRL-1; UNQ3033 Summary Predicted to enable cytokine activity. Predicted to be involved in immune system process and signal transduction. Predicted to be located in extracellular space. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward bone marrow (RPKM 28.7) See more Orthologs all
VSTM2A, Official Symbol VSTM2Aprovided by HGNC Official Full Name V-set and transmembrane domain containing 2Aprovided by HGNC Primary source HGNC:HGNC:28499 See related Ensembl:ENSG00000170419 AllianceGenome:HGNC:28499 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VSTM2 Summary Predicted to enable identical protein binding activity. Involved in several processes, including positive regulation of brown fat cell differentiation; positive regulation of lipid storage; and positive regulation of white fat cell proliferation. Predicted to be located in extracellular region. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 3.8), prostate (RPKM 1.6) and 4 other tissues See more Orthologs mouse all
VSTM2A-OT1, Official Symbol VSTM2A-OT1provided by HGNC Official Full Name VSTM2A overlapping transcript 1provided by HGNC Primary source HGNC:HGNC:50770 See related Ensembl:ENSG00000224223 AllianceGenome:HGNC:50770 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GS1-18A18.1 Expression Biased expression in brain (RPKM 2.1), adrenal (RPKM 1.3) and 5 other tissues See more
VSTM2B, Official Symbol VSTM2Bprovided by HGNC Official Full Name V-set and transmembrane domain containing 2Bprovided by HGNC Primary source HGNC:HGNC:33595 See related Ensembl:ENSG00000187135 AllianceGenome:HGNC:33595 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 9.7) See more Orthologs mouse all
VSTM2B-DT, Official Symbol VSTM2B-DTprovided by HGNC Official Full Name VSTM2B divergent transcriptprovided by HGNC Primary source HGNC:HGNC:27615 See related Ensembl:ENSG00000264515 AllianceGenome:HGNC:27615 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
VSTM2L, Official Symbol VSTM2Lprovided by HGNC Official Full Name V-set and transmembrane domain containing 2 likeprovided by HGNC Primary source HGNC:HGNC:16096 See related Ensembl:ENSG00000132821 MIM:616537; AllianceGenome:HGNC:16096 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf102; dJ1118M15.2 Summary Predicted to enable cell-cell adhesion mediator activity. Involved in negative regulation of neuron apoptotic process. Located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 19.4), gall bladder (RPKM 10.9) and 7 other tissues See more Orthologs mouse all
VSTM4, Official Symbol VSTM4provided by HGNC Official Full Name V-set and transmembrane domain containing 4provided by HGNC Primary source HGNC:HGNC:26470 See related Ensembl:ENSG00000165633 AllianceGenome:HGNC:26470 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C10orf72 Summary Predicted to act upstream of or within several processes, including endothelial cell migration; retina blood vessel maintenance; and vasculature development. Predicted to be located in extracellular region and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in adrenal (RPKM 18.4), ovary (RPKM 14.7) and 19 other tissues See more Orthologs mouse all
VSTM5, Official Symbol VSTM5provided by HGNC Official Full Name V-set and transmembrane domain containing 5provided by HGNC Primary source HGNC:HGNC:34443 See related Ensembl:ENSG00000214376 AllianceGenome:HGNC:34443 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C11orf90 Summary Predicted to be involved in filopodium assembly; positive regulation of excitatory synapse assembly; and protein homooligomerization. Predicted to act upstream of or within ventral spinal cord development. Predicted to be located in axon; dendrite; and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in placenta (RPKM 1.5), stomach (RPKM 0.6) and 9 other tissues See more Orthologs mouse all
VSX1, Official Symbol VSX1provided by HGNC Official Full Name visual system homeobox 1provided by HGNC Primary source HGNC:HGNC:12723 See related Ensembl:ENSG00000100987 MIM:605020; AllianceGenome:HGNC:12723 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPD; KTCN; PPCD; RINX; KTCN1; PPCD1; CAASDS Summary The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all
VSX2, Official Symbol VSX2provided by HGNC Official Full Name visual system homeobox 2provided by HGNC Primary source HGNC:HGNC:1975 See related Ensembl:ENSG00000119614 MIM:142993; AllianceGenome:HGNC:1975 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RET1; CHX10; HOX10; MCOP2; MCOPCB3 Summary This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. [provided by RefSeq, Oct 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all
VTA1, Official Symbol VTA1provided by HGNC Official Full Name vesicle trafficking 1provided by HGNC Primary source HGNC:HGNC:20954 See related Ensembl:ENSG00000009844 MIM:610902; AllianceGenome:HGNC:20954 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRG1; LIP5; SBP1; DRG-1; My012; 6orf55; C6orf55; HSPC228 Summary C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 16.7), colon (RPKM 13.5) and 25 other tissues See more Orthologs mouse all
VTA1P1, Official Symbol VTA1P1provided by HGNC Official Full Name vesicle trafficking 1 pseudogene 1provided by HGNC Primary source HGNC:HGNC:50483 See related Ensembl:ENSG00000224999 AllianceGenome:HGNC:50483 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTA1P2, Official Symbol VTA1P2provided by HGNC Official Full Name vesicle trafficking 1 pseudogene 2provided by HGNC Primary source HGNC:HGNC:50484 See related AllianceGenome:HGNC:50484 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTCN1, Official Symbol VTCN1provided by HGNC Official Full Name V-set domain containing T cell activation inhibitor 1provided by HGNC Primary source HGNC:HGNC:28873 See related Ensembl:ENSG00000134258 MIM:608162; AllianceGenome:HGNC:28873 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291 Summary This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in kidney (RPKM 5.0), pancreas (RPKM 2.8) and 9 other tissues See more Orthologs mouse all
VTI1A, Official Symbol VTI1Aprovided by HGNC Official Full Name vesicle transport through interaction with t-SNAREs 1Aprovided by HGNC Primary source HGNC:HGNC:17792 See related Ensembl:ENSG00000151532 MIM:614316; AllianceGenome:HGNC:17792 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MMDS3; MVti1; VTI1RP2; Vti1-rp2 Summary The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in brain (RPKM 1.6), bone marrow (RPKM 1.4) and 25 other tissues See more Orthologs mouse all
VTI1B, Official Symbol VTI1Bprovided by HGNC Official Full Name vesicle transport through interaction with t-SNAREs 1Bprovided by HGNC Primary source HGNC:HGNC:17793 See related Ensembl:ENSG00000100568 MIM:603207; AllianceGenome:HGNC:17793 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE Summary Enables SNARE binding activity and chloride channel inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 68.1), kidney (RPKM 45.6) and 25 other tissues See more Orthologs mouse all
VTI1BP1, Official Symbol VTI1BP1provided by HGNC Official Full Name vesicle transport through interaction with t-SNAREs 1B pseudogene 1provided by HGNC Primary source HGNC:HGNC:43727 See related AllianceGenome:HGNC:43727 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTI1BP2, Official Symbol VTI1BP2provided by HGNC Official Full Name vesicle transport through interaction with t-SNAREs 1B pseudogene 2provided by HGNC Primary source HGNC:HGNC:43728 See related AllianceGenome:HGNC:43728 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTI1BP4, Official Symbol VTI1BP4provided by HGNC Official Full Name vesicle transport through interaction with t-SNAREs 1B pseudogene 4provided by HGNC Primary source HGNC:HGNC:43730 See related Ensembl:ENSG00000227759 AllianceGenome:HGNC:43730 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTN, Official Symbol VTNprovided by HGNC Official Full Name vitronectinprovided by HGNC Primary source HGNC:HGNC:12724 See related Ensembl:ENSG00000109072 MIM:193190; AllianceGenome:HGNC:12724 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VN; V75; VNT Summary The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. [provided by RefSeq, Aug 2020] Expression Restricted expression toward liver (RPKM 1572.2) See more Orthologs mouse all
VTRNA1-1, Official Symbol VTRNA1-1provided by HGNC Official Full Name vault RNA 1-1provided by HGNC Primary source HGNC:HGNC:12654 See related Ensembl:ENSG00000199990 MIM:612695; AllianceGenome:HGNC:12654 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VR1; HVG1; vRNA; hvg-1; VAULTRC1 Summary Vaults are large cytoplasmic ribonucleoproteins of about 13 MD. They are composed of a major vault protein, MVP (MIM 605088), 2 minor vault proteins, TEP1 (MIM 601686) and PARP4 (MIM 607519), and a nontranslated RNA component, VTRNA1-1 (Kickhoefer et al., 1999 [PubMed 10551828]).[supplied by OMIM, Mar 2009]
VTRNA1-2, Official Symbol VTRNA1-2provided by HGNC Official Full Name vault RNA 1-2provided by HGNC Primary source HGNC:HGNC:12655 See related Ensembl:ENSG00000202111 MIM:612696; AllianceGenome:HGNC:12655 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VR2; HVG2; hvg-2; VAULTRC2
VTRNA1-3, Official Symbol VTRNA1-3provided by HGNC Official Full Name vault RNA 1-3provided by HGNC Primary source HGNC:HGNC:12656 See related Ensembl:ENSG00000202515 MIM:612697; AllianceGenome:HGNC:12656 Gene type ncRNA RefSeq status PROVISIONAL Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VR3; HVG3; hvg-3; VAULTRC3
VTRNA2-2P, Official Symbol VTRNA2-2Pprovided by HGNC Official Full Name vault RNA 2-2, pseudogeneprovided by HGNC Primary source HGNC:HGNC:46889 See related Ensembl:ENSG00000251900 AllianceGenome:HGNC:46889 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VTRNA3-1P, Official Symbol VTRNA3-1Pprovided by HGNC Official Full Name vault RNA 3-1, pseudogeneprovided by HGNC Primary source HGNC:HGNC:23027 See related Ensembl:ENSG00000199422 AllianceGenome:HGNC:23027 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HVG4; HVGX; hvg-4; VTRNA3P; VAULTRC4
VWA1, Official Symbol VWA1provided by HGNC Official Full Name von Willebrand factor A domain containing 1provided by HGNC Primary source HGNC:HGNC:30910 See related Ensembl:ENSG00000179403 MIM:611901; AllianceGenome:HGNC:30910 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WARP; HMNMYO Summary VWA1 belongs to the von Willebrand factor (VWF; MIM 613160) A (VWFA) domain superfamily of extracellular matrix proteins and appears to play a role in cartilage structure and function (Fitzgerald et al., 2002 [PubMed 12062410]).[supplied by OMIM, Nov 2010] Expression Broad expression in prostate (RPKM 28.1), placenta (RPKM 11.5) and 23 other tissues See more Orthologs mouse all
VWA2, Official Symbol VWA2provided by HGNC Official Full Name von Willebrand factor A domain containing 2provided by HGNC Primary source HGNC:HGNC:24709 See related Ensembl:ENSG00000165816 MIM:618281; AllianceGenome:HGNC:24709 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMACO; CCSP2; NET42; CCSP-2 Summary This gene encodes a member of the von Willebrand factor A-like domain protein superfamily. The encoded protein is localized to the extracellular matrix and may serve as a structural component in basement membranes or in anchoring structures on scaffolds of collagen VII or fibrillin. This gene has been linked to type 1A diabetes and is a candidate serological marker for colon cancer. [provided by RefSeq, Jan 2013] Expression Broad expression in stomach (RPKM 3.7), prostate (RPKM 3.3) and 18 other tissues See more Orthologs mouse all
VWA3A, Official Symbol VWA3Aprovided by HGNC Official Full Name von Willebrand factor A domain containing 3Aprovided by HGNC Primary source HGNC:HGNC:27088 See related Ensembl:ENSG00000175267 AllianceGenome:HGNC:27088 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lung (RPKM 3.4), testis (RPKM 1.7) and 2 other tissues See more Orthologs mouse all
VWA3B, Official Symbol VWA3Bprovided by HGNC Official Full Name von Willebrand factor A domain containing 3Bprovided by HGNC Primary source HGNC:HGNC:28385 See related Ensembl:ENSG00000168658 MIM:614884; AllianceGenome:HGNC:28385 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCAR22 Summary This gene encodes an intracellular protein that contains a von Willebrand factor type A domain. Intracellular proteins with VWA domains are thought to function in transcription, DNA repair, ribosomal and membrane transport and the proteasome. Mutations in this gene are associated with Spinocerebellar ataxia, autosomal recessive 22. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2017] Expression Restricted expression toward testis (RPKM 15.5) See more Orthologs mouse all
VWA5A, Official Symbol VWA5Aprovided by HGNC Official Full Name von Willebrand factor A domain containing 5Aprovided by HGNC Primary source HGNC:HGNC:6658 See related Ensembl:ENSG00000110002 MIM:602929; AllianceGenome:HGNC:6658 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCSC1; BCSC-1; LOH11CR2A Summary Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in colon (RPKM 15.2), gall bladder (RPKM 14.6) and 24 other tissues See more Orthologs all
VWA5B1, Official Symbol VWA5B1provided by HGNC Official Full Name von Willebrand factor A domain containing 5B1provided by HGNC Primary source HGNC:HGNC:26538 See related Ensembl:ENSG00000158816 AllianceGenome:HGNC:26538 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Low expression observed in reference dataset See more Orthologs mouse all
VWA5B2, Official Symbol VWA5B2provided by HGNC Official Full Name von Willebrand factor A domain containing 5B2provided by HGNC Primary source HGNC:HGNC:25144 See related Ensembl:ENSG00000145198 AllianceGenome:HGNC:25144 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Biased expression in adrenal (RPKM 30.4), brain (RPKM 2.3) and 1 other tissue See more Orthologs mouse all
VWA7, Official Symbol VWA7provided by HGNC Official Full Name von Willebrand factor A domain containing 7provided by HGNC Primary source HGNC:HGNC:13939 See related Ensembl:ENSG00000204396 MIM:609693; AllianceGenome:HGNC:13939 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G7c; NG37; C6orf27 Summary Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in stomach (RPKM 3.5), kidney (RPKM 2.9) and 25 other tissues See more Orthologs mouse all
VWA8, Official Symbol VWA8provided by HGNC Official Full Name von Willebrand factor A domain containing 8provided by HGNC Primary source HGNC:HGNC:29071 See related Ensembl:ENSG00000102763 MIM:617509; AllianceGenome:HGNC:29071 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP97; P7BP2; KIAA0564 Summary Predicted to enable ATP binding activity. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 6.4), fat (RPKM 4.0) and 25 other tissues See more Orthologs mouse all
VWA8-AS1, Official Symbol VWA8-AS1provided by HGNC Official Full Name VWA8 antisense RNA 1 (head to head)provided by HGNC Primary source HGNC:HGNC:44270 See related Ensembl:ENSG00000278338 AllianceGenome:HGNC:44270 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
VWA8P1, Official Symbol VWA8P1provided by HGNC Official Full Name von Willebrand factor A domain containing 8 pseudogene 1provided by HGNC Primary source HGNC:HGNC:44271 See related Ensembl:ENSG00000250289 AllianceGenome:HGNC:44271 Gene type pseudo RefSeq status INFERRED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
VWC2, Official Symbol VWC2provided by HGNC Official Full Name von Willebrand factor C domain containing 2provided by HGNC Primary source HGNC:HGNC:30200 See related Ensembl:ENSG00000188730 MIM:611108; AllianceGenome:HGNC:30200 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNQ739; PSST739 Summary This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009] Expression Biased expression in heart (RPKM 2.5), ovary (RPKM 2.4) and 3 other tissues See more Orthologs mouse all
VWC2L, Official Symbol VWC2Lprovided by HGNC Official Full Name von Willebrand factor C domain containing 2 likeprovided by HGNC Primary source HGNC:HGNC:37203 See related Ensembl:ENSG00000174453 MIM:619794; AllianceGenome:HGNC:37203 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to be involved in negative regulation of BMP signaling pathway. Predicted to act upstream of or within positive regulation of neuron differentiation. Predicted to be located in extracellular region and synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward brain (RPKM 1.2) See more Orthologs mouse all
VWC2L-IT1, Official Symbol VWC2L-IT1provided by HGNC Official Full Name VWC2L intronic transcript 1provided by HGNC Primary source HGNC:HGNC:41508 See related Ensembl:ENSG00000224257 AllianceGenome:HGNC:41508 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Expression Low expression observed in reference dataset See more
VWCE, Official Symbol VWCEprovided by HGNC Official Full Name von Willebrand factor C and EGF domainsprovided by HGNC Primary source HGNC:HGNC:26487 See related Ensembl:ENSG00000167992 MIM:611115; AllianceGenome:HGNC:26487 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VWC1; URG11 Summary Predicted to enable calcium ion binding activity. Involved in cellular response to virus. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in ovary (RPKM 4.8), liver (RPKM 2.1) and 15 other tissues See more Orthologs mouse all