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Among haematological parameters, lymphopenia is clearly associated with disease severity; 88 patients who died from COVID-19 had significantly lower lymphocyte counts than survivors.
In fact, repletion of lymphocytes may be an important factor for recovery [3] . Other blood 90 cells, including white blood cells, neutrophils, eosinophils, platelets and CD8 cell counts were 91 partly only predictors in discriminating mild from severe COVID-19 (Table1); their 92 significance is still ambiguous. Granulocyte colony stimulating factor (G-CSF) was elevated 93 in ICU patients and significantly associated with the severity of disease (Table1).
Patients with severe COVID-19 appear to have signs of liver dysfunction more frequently 96 than those with milder disease. An increase in alanine aminotransferase (ALT), aspartate 97 aminotransferase (AST) and total bilirubin levels has been observed among many ICU 98 patients [4] ( Table 1) 
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