plueme/wizJson huggingface dataset:
location: nan, 'Thailand 
year: 2022 source: HSRI 
title: Economic Evaluation of Programmatic Screening Strategies for Latent Tuberculosis Infection (LTBI) in TB Contacts 
abstract:Introduction: Tuberculosis (TB) is a communicable disease caused by M. tuberculosis. Contacts of TB cases become clinically active TB or remain in the latent tuberculosis infection (LTBI), which is subsequent progression to tuberculosis disease. Currently, the available tests for LTBI diagnosis include tuberculin skin test (TST) and interferon-gamma release assay (IGRA). In Thailand, IGRA test is costly and has not been included in the benefit package. The results from this study can be used as an evidence informed policy whether IGRA test should be included in the benefit package and can be applied to support the strategies to eradicate TB. Objectives: To evaluate cost-utility analysis, budget impact analysis and feasibility analysis of LTBI diagnosis for contacts of TB patients using societal and government perspectives. Methodology: Cost-utility analysis using a decision tree and Markov model was performed to simulate the costs and utilities, and to estimate the budget impact of contacts with pulmonary TB patients. All parameters were obtained from published studies. Lifetime horizon was applied with both costs and outcomes discounted by 3%, as recommended by the guidelines of economic evaluation in Thailand. One way and probabilistic sensitivity analyses were conducted to examine the uncertainty of input parameters. This study considered three alternative diagnosis strategies as follows: 1) No screening, 2) TST alone to diagnose LTBI, if TST test was positive, treatment would be provided, and 3) IGRA alone to diagnose LTBI, if IGRA test was positive, treatment would be provided. Focus group discussion and literature reviews were applied for feasibility analysis. Results: The incremental cost-effectiveness ratios (ICER) of IGRA alone compared with TST alone was THB 1,220,287 per QALY gained. At the willingness to pay (WTP) THB 160,000 per QALY gained, IGRA would not be cost-effective. If the price of IGRA was decreased to THB 575 per test, the strategy of IGRA would be cost-effective. Five-year budget for TST and IGRA was estimated to be THB 148 million and THB 330 million, respectively. The barriers for IGRA implementation were lack of laboratory infrastructure and limited availability of laboratory personnel.
location: nan, 'Thailand 
year: 2022 source: HSRI 
title: Health Adjusted Life Expectancy Region 3, 2022 
abstract:The purposes of this were to study the health adjusted life expectancy (HALE) of people in health region 3, 2022, and prioritize diseases and health hazards that are important problems in health region 3. The cross-sectional study design was used. A sample of 1,230 Thai people aged 10 and over in the responsible area of health region 3, were randomly selected using a multistage sampling technique. The EQ-5D-5L Thai Version is composed of Mobility Self-care Usual activities Pain/discomfort, and Anxiety/drepression. The Sullivan method was used to analyze the data. For priority diseases and health hazards problems in health region 3, data was collected by the priority setting methods were seven components of the World Health Organization. From the committee of the health region 3. The results revealed that the HALE of people in health region 3, 2022 was 65.16 years. Lower than the Thailand target set by at least 68 years. The self-care dimension had the greatest effect on utility scores. Health status at best scores 48.94% and lowest score 0.08%. The priority diseases and health hazards that are important problems in health region 3, showed that the top three were stroke, ischemic heart disease, and road traffic injuries. Further research should be recommended to determine the model or approach to increasing HALE. as well as developing policies and measures to solve disease and health hazards and allocating sufficient resources to lead to more effective and efficient implementation.
location: nan, 'Thailand 
year: 2022 source: HSRI 
title: A Multicenter Study of Contamination and Spreading Due to Multidrug-Resistant Acinetobacter Baumannii in Pediatric and Neonatal Intensive Care Units 
abstract:Acinetobacter baumannii (A. baumannii) is a gram-negative bacterium that is the leading cause of nosocomial infections. This organism usually develops antimicrobial resistance, resulting in multi-drugs resistant A. baumannii. Adult and pediatric patients, including neonates with A. baumannii infections have a high mortality rate. The spread of A. baumannii in hospitals occurs through contact transmission, which could be direct contact with the hands of healthcare professionals, or indirect contact through contacts with the bacteria in various environments in the ward. This study aims to study the pattern of A. baumannii transmission in the Pediatric and Neonatal Intensive Care Unit of Thung Song Hospital, Maharaj Nakhon Si Thammarat Hospital and Tha Sala Hospital. Specimens were collected in 1) each patient's touch points, consisting of a bed or a cabinet of A. baumannii infected patients, an adjacent bed or cabinet, healthcare providers' hands and clothing. 2) Common touch points in the ward consisted of treatment record files, work desks in the ward, doorknobs, computers, telephones, sinks and bathtubs. The specimens were collected from October 2021 – September 2022. During the 12-month period, there were 27 patients with confirmed cultures of A. baumannii, of which 15 were from the infant intensive care unit of Thung Song Hospital, 5 patients from the pediatric intensive care unit of Maharaj Hospital and 7 patients from the pediatric intensive care unit of Maharaj Hospital. The results from both hospitals showed that the most contaminated areas of A. baumannii were each patient's bed (29.63%) and adjacent beds (29.63%). The other contaminated areas in the ward were healthcare providers' clothing (22.22%), infusion set (14.81%), monitor (11.11%) and healthcare providers' hands (11.11%). Regarding common touch points, the bathtub area (25.93%) was the most contaminated, followed by the patient's file (18.52%) and the desk in the ward (18.52%).
location: nan, 'Thailand 
year: 2023 source: HSRI 
title: Evaluation of the Implementation of Fast Track Surgery for Hip Fracture Program in Pilot Hospitals in Thailand and the Impact of COVID-19 on the System and Patient Outcomes (Year 1) 
abstract:Hip fracture in older people is one of the major public health issues worldwide including Thailand. Appropriate care for older people with hip fracture includes fast track surgery and perioperative multidisciplinary team care. This study aimed to monitor pilot hospitals involved in ‘Fast Track Surgery for Hip Fracture Program’ to explore patients’ outcomes and factors associated with the clinical outcomes. We discovered that the operation rate for hip fracture in older people in Thailand remains suboptimal. The rate of non-operative surgery remains high around 40 %. Hospitals in pilot project had higher rate of patients received ‘fast track surgery’ compared to hospitals nationwide. Moreover, pilot hospitals had made significant changes to the policy and process of care for this group of patients. However, some recommended processes could not be arranged. With respect to patients’ outcomes, the mortality rates tend to be reducing in pilot hospitals but did not reach statistically significant. This could stem from the finding that several recommended quality indicators could not be arranged. Multivariate linear regression models were carried out to determine factors at hospital level affecting mortality. Having internists involved in postoperative care significantly associated with lower one-year mortality. Having rehabilitation specialists involved in postoperative care is also associated with lower three-month mortality. Covid-19 pandemic did not have negative impact to operation rate and mortality for hip fracture patients in Thailand.
location: nan, 'Thailand 
year: 2022 source: HSRI 
title: Developmental Evaluation of Payment Methods to Support New Normal Health Care Delivery Outside the Hospital for Patients with Chronic Conditions (Year 1) 
abstract:COVID-19 pandemics effected health systems in term of increasing of workload caused by the number of infectious, also the effected on routine health services especially continuity of healthcare deliveries for the patients with chronic conditions. The Ministry of public health and the National health security office established the new-normal healthcare policy which emphasized on outside hospital care deliveries by strengthening primary care services together with the partnership including private rehabilitation clinics, nursing clinics and drug stores. This project applied the evaluation development concept by applying mixed-method research design to evaluate the implementation of the policy and synthesized the policy recommendations based on the findings. We performed the literature review, together with analysis of secondary quantitative data and qualitative data collecting from multi-stakeholders. We found that health burden of non-communicable diseases and conditions are high and increasing over the time especially on hypertension, diabetes, and related complications such as stroke. The services utilizations of this group of patients were disrupted by lock-down policy during COVID-19 pandemics. There were existing of new-normal care deliveries during 2020-2022 especially there were the high number of telemedicine which performed by public health facilities. However, the services provided by private rehabilitation clinics and private nursing clinics were still limited in term of number of clinics, number of patients, and also in the term of geographical distributions of services. According to our findings, we strongly emphasized that primary care should be the core of new-normal health services for the patients with chronic conditions. To delivery high effective coverage care, the area manager position and role should be established and should be paid by NHSO at primary care level. Individual care plan should be done by care team and should be monitored and evaluated by area manager. Effective information systems should be designed and implemented and should be able to connect every stakeholder in primary care network. Also, the information systems must allow the patients to confirm their received care by private partners. The authorities should arrange the platform that allow all partners working together effectively and analyzing the routine data for better policy designing and decisioning.
location: nan, 'Thailand 
year: 2023 source: HSRI 
title: Evaluating the Performance of the Global Diet Quality Score for Determining Overall Dietary Quality Among Thai Adults for Integrating into Non-Communicable Disease Prevention System 
abstract:The Global Diet Quality Score (GDQS) is a comprehensive metric that covers both the risks of nutritional deficiency and the risk of diet-related noncommunicable diseases (NCD). Validation tests were previously performed using secondary data from various countries. However, the study of the application of the GDQS to the Thai population is still necessary. Because Thai food usually consists of a variety of components, the GDQS may reflect the risks of nutrient inadequacy and the risks of NCD differently from the previous studies. Objective: This study aimed to characterize the GDQS’s performance by estimating the associations between the GDQS and diverse outcomes reflective of undernutrition and diet-related NCD risks. Methods: A cross-sectional study was conducted in Thai adults aged 40-60 years. GDQS was calculated from dietary data collected using a 24-hr dietary recall (24HR), a semi-quantitative food frequency questionnaire (FFQ), and the GDQS-Assessment System (GDQS-AS). Additional metrics were also calculated, including the Minimum Dietary Diversity for Women (MDD-W) and the Alternative Healthy Eating Index-2010 (AHEI-2010). Nutritional status was determined through anthropometric, body composition, blood pressure, and biochemical marker assessments. Spearman rank correlations and multivariable adjusted regression models were performed to evaluate the associations between GDQS and diverse outcomes reflective of undernutrition and diet-related NCD risks. Wolfe test and Wald test were used to compare the strength and trend of the correlations of the GDQS and outcomes between different dietary data collection methods and different metrics. Results: The prevalence of overweight to obesity (Body mass index ≥25 kg/m2) was 47.5%. Anemia was reported in 8.9% of men and 23.8% of women, hypertension in 54.1% of men and 39.4% of women, and metabolic syndrome in 42.5% of men and 35.9% of women. Mean urinary sodium excretion was 3,397 mg/day (147.7 mmol/day). The GDQS calculated by GDQS-AS and FFQ were relatively similar, while the GDQS-24HR was lower. Multivariable adjusted regression analysis found that GDQS-AS performed better in reflecting nutrient intakes, nutrient adequacy, and nutritional outcomes than GDQS computed from 24HR and FFQ. GDQS, MDD-W, and AHEI-2010 similarly performed in indicating nutrient adequacy and risks of NCD. Nevertheless, GDQS computed from FFQ better reflected nutrient adequacy. Conclusion: Overall, GDQS-AS had a relatively stronger performance in capturing both nutrient intakes and nutritional outcomes compared with GDQS computed from other methods, whereas GDQS scored from FFQ was outperformed
in capturing nutrient adequacy. Findings from this study only reflected a cross-sectional correlation between GDQS and nutrient adequacy and NCD risks. Thus, further study to longitudinally explore the correlations between GDQS and NCD risks is required.
location: nan, 'Thailand 
year: 2023 source: HSRI 
title: Development Project of Personal Health Record Connect to the COVID-19 Vaccine Management Program in the Area of Health Region 9 
abstract:This study is a developmented research with the objectives as analysis purposes. synthesis and development electronic Personal Health Record (PHRs) systems that are desirable to the health system
of Thai people by connecting the database of the COVID-19 Vaccine Information Management Program. Health Region 9 was selected as the target area. and establishing a framework for the development of a prototype central platform and an information network for the exchange of PHR systems between people and healthcare unit. Development system for connecting and retrieving data for display on smart phone. And central cloud development for interoperability between the different databases. Including designing user interface on the Mohpromt application. The results showed that The electronic personal health record should be Hybrid or Interconnected that can display the healthcare treatment and able to record health data by themselves. Developing program on Mohpromt platform which supports collaboration from multiple departments. Standards data and level of information to be displayed on the application in 3 levels: 1.) General information is the basic that shown immediately after registering Mohpromt application. 2.) Health information for individual That must go through a verification process and verify their identity before accessing and 3.) Treatment information for Healthcare Provider to view history treatment from others and must be obtained permission from the data’s owner before accessing. Personal health data is connected and retrieved between the COVID-19Vaccine management program and various hospital information systems via API to display on the Mohpromt application with more than 1,000 healthcare units. covering both the target group in region 9 and others. Established data governance regarding to the collection and use of personal data in limited According to the Personal Data Protection Act. Application evaluation divided into two aspects: satisfaction on technical quality and application content. Evaluation results from 100 users in region 9 in terms of technical quality and application content. Application development results in terms of technical quality and application content overall, it was a high level (x = 4.14) and users were satisfied with the PHR on the application overall, it was at a very good level (x = 4.89). The overall rating for the application, from 1 to 5 points, users gave an average score of 4.22 and satisfaction with the PHR menu on the application very favorably. 95 percent of users want to use PHR menu and will recommend the others. and suggested that other health behavior data should be recorded manually.
location: nan, 'Thailand 
year: 2023 source: HSRI 
title: Improvement of Dental Sealant Effectiveness by Using Moisture Control Innovation (Tongue and Cheek Retractor and Saliva Contamination: SS-Suction): Randomized Controlled Trial) 
abstract:This research aimed to study dental nurses’ satisfaction and effectiveness of moisture control innovation (for tongue and cheek retractor, and saliva contamination (SS-suction)), toward dental sealant service without dental assistants compared to standard service; moisture control with cotton roll and dental assistant. This study was randomized controlled trial implemented among 15 dental nurses who attended a workshop on using SS-suction, recording satisfaction data toward using and safety, recording students’ data and revised dental sealing technic. Dental nurses received SS-suctions and then provided sealant service to 482 children aged 6–8 years old at sub-district health-promoting hospitals. Children were simply randomly allocated into either experimental or control groups. The children in the experiment group were 244, and in the control group, 238. Data collection on dental nurses’ characteristics, satisfaction with SS-suction for each sealed tooth during service. At 15-18 months, sealed teeth were assessed for retention and caries. Quality control for data collection was the validity and reliability of the satisfaction questionnaire and calibration on sealant retention examination. The results showed the median satisfaction level for SS-suction use was 9 out of 10, and the percentage of children with pain during insertion or removal was 17–18. The pain was from a feeling of pressure and disappeared when the suction was in place. Retention and caries were not significantly different between the experiment and control groups. Full retention on the occlusal surface were 32.5% and 31.4% and on the buccal surface were 16.8 and 18.3 in the experiment and control groups, respectively. Caries on the occlusal surface were 26.6% and 27.6% and those on buccal surface were 35.4 and 36.2 in the experiment and control groups. In conclusion, dental nurses were satisfied with SS-Suction both in function and safety. The effectiveness at 15–18 months of SS-Suction was compatible with standard procedure.
location: nan, 'Thailand 
year: 2023 source: HSRI 
title: Immunogenicity of the Third Covid-19 Vaccines Booster Dose in Adults with Completed 2 Doses as Recommended by the Ministry of Public Health 
abstract:Objectives: To report the safety and immunogenicity profile of a protein subunit vaccine (CovovaxTM) given as a third (booster) dose to individuals primed with different primary vaccine regimens. Methods: A third dose was administered to individuals with an interval range of 3-10 months after the second dose. The four groups were classified according to their primary vaccine regimens, including two-dose BBIBP-CorV, AZD1222, BNT162b2, and CoronaVac/AZD1222. Immunogenicity analysis was performed to determine binding antibodies, neutralizing activity, and the T-cell responses. Results: Overall, 210 individuals were enrolled and boosted with the CovovaxTM vaccine. The reactogenicity was mild to moderate. Most participants elicited a high level of binding and neutralizing antibody against Wild-type and Omicron variants after the booster dose. In participants who were anti nucleocapsid immunoglobulin G-negative from all groups, a booster dose could elicit neutralizing activity to Wild-type and Omicron variants by more than 95% and 70% inhibition at 28 days, respectively. The CovovaxTM vaccine could elicit a cell-mediated immune response. Conclusion: The protein subunit vaccine (CovovaxTM) can be proposed as a booster dose after two different priming dose regimens. It has strong immunogenicity and good safety profile
location: nan, 'Thailand 
year: 2022 source: HSRI 
title: The Development of Artificial Intelligence (AI) to Detect Pathological Lesions on Plain Chest X-Ray for the Screening of Pulmonary Tuberculosis, Lung Cancer and Other Diseases 
abstract:Digital chest x-ray images are the most widely used medical diagnostic tool Nowsaday. They helps in the diagnosis of diseases such as pulmonary tuberculosis and lung cancer. There are millions of chest radiographs produced by hospitals each year. But only less than 10% of the images were interpreted by radiologists. The rest of the images are often interpreted by general practitioners. But interpreting results by general practitioners is likely to be wrong. Several studies have shown that general practitioners may have chances to misinterpret the results including misdiagnose or missed diagnose up to 20-50% of the images with lung cancer lesions. In addition, the interpretation of results by a single radiologists still has a 5-9 percent chance of error. Artificial intelligence (AI) may be an option to assist in the screening of chest radiographs with lesions or abnormalities that must be reinterpreted by a radiologist. In this study, a database of chest radiographs from the tuberculosis and lung cancer database was created. For the development of AI systems using U-Net and SegNet neural networks, it was found that the SegNet model network yielded satisfactory screening results. Sematic segmentation using the SegNet model and using pre-tutorial VGG19, which added a dropout with a probability value of 0.4. After designing and teaching the network with various patterns until the level of accuracy is satisfactory. The AI was tested with testing images. For the test with 17 images, Small1I lesions was best identified by the AI with an average IoU accuracy of 90.23%, followed by cancer lesions with an average IoU of 89.45%. The lowest correctly classified lesion was cavity with an accuracy of only 5.71%. The AI was further tested with a set of 26 images with cancer lesions. The AI did not detect 4 malignant lesions. When tested with 10 images without lesions the AI incorrectly identified a couple of lesions in 2 images. From the results, this artificial intelligence should be implemented in the form of a Triage to screen images before consulting a radiologist. This can reduce the workload of radiologists and general physicians and thus may be of economic value in terms of radiologist and general practitioner wages and time.