plueme/wizJson huggingface dataset:
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Study of Contamination and Control of Antibiotic Resistance Bacteria from Hospital and Pig Farm 
abstract:This study had investigated contaminants and control of antimicrobial-resistant microorganisms (AMR) from hospitals and pig farms. In the study of pig farms, the questionnaire survey was conducted at four farms nearby the surface water body in Prachinburi province. It shows that 50% of the farms use antibiotics for disease prevention and treatment, while that 50% mix antibiotics with feed. The commonly used antibiotics are Amoxycillin (100%), Enrofloxacin (50%), and colistin (25%). The residual antibiotics found during the rainy season were Amoxycillin (54%), Florfenicol (14%), and Tiamulin (13%), of which the concentrations were significantly higher than those found during the summer season (P<0.05). The detection of antibiotic resistance among 143 isolates of E. coli, 29% was in pig manure, 36% in wastewater, and 33% in treated water. Nevertheless, the antibiotics that those isolates were found more than 50% resistant against were Ampicillin (90%), Florfenicol (67%), and Tetracycline (66%), 13% of ESBL. None was of Imipenem resistance. The resistant genes of E. coli were found higher for beta-lactamase followed by Tetracycline (tetA, tetB) and Aminoglycoside (aadA1, aadA2, aadB), while no mcr1 gene showed in all samples. The probability that microorganisms having identical genes of 1 pair (100%) and 80% similarity was about 20%. The study of treatment efficacy of activated sludge (AS) wastewater treatment plant of Chao Phraya Abhaibhubejhr hospital revealed 68-69% removals of basic pollutants, and 20-100% removals of 13 types of antibiotics. A similar AMR population (60-100%) to 20 antibiotics of E. coli, K. pneumoniae, and A. baumannii appeared in wastewater and the AS effluent. The study of pilot-scale membrane bioreactor (MBR) operated without excess sludge wastage in hospital wastewater treatment revealed 79-100% removals of basic pollutants and 32-100% removals of antibiotics. The MBR could effectively remove microorganisms (100%). Antimicrobial resistant test in the MBR sludge revealed higher percentages of sensitive colonies, especially those of K. pneumoniae and A. baumannii >80% were sensitive to 75-85% of tested antibiotics. The 1-2 log reduction of antibiotic resistance genes (ARGs) in the influent with 106-1010 copies/ml by the MBR had been achieved. The use of post-chlorination and ozonation slightly improved in removals of ARGs.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: The Review of International Cooperation Frameworks on Health Management for Migrants and Cross-national Population 
abstract:This study is a documentary research and aimed to study and review the contents of international cooperation frameworks at global, regional and national levels concerning issues on migration management and health care provision for migrant workers and cross-national populations and health collaboration frameworks between Thailand and Mekong sub-region countries, especially Cambodia, Lao PDR and Myanmar as well as mechanisms for implementation, coordination, monitoring and evaluation of the international cooperation frameworks. Results of the study revealed that global and regional international cooperation frameworks, with selected criteria mentioned above, have provided concepts and guiding principles for migration management and promotion of migrant and refugee health, which are harmoniously interlinked and aimed to realize the sustainable development goals (SDGs) that facilitate orderly, safe, regular and responsible migration and mobility of people (SDG target 10.7) and ensure healthy lives and promote well-being for all at all ages (SDG goal 3) including achieve universal health coverage (SDG target 3.8). The concepts and guiding principles can be applied by member countries as guidelines for dealing with problems and issues related to migrant workers and cross-national populations or can be used as conceptual frameworks for developing additional agreements to address the issues with countries of mutual interests. Since health management for migrant workers cannot be carried out alone by one country, collaboration and cooperation among the countries of origin or the sending countries and countries of destination or receiving countries are required. As movement of migrant workers can provide both positive and negative impacts on the economic development of countries and the region, integration of migrant health management as a public health issue of international cooperation in existing regional economic cooperation frameworks, such as ACMECS and GMS will help mobilize resources and efforts from member countries to address this issue in more effective and concrete ways, thus, makes the migration to be a positive impact for the overall economic development of the member countries and the region. Recommendations for better dealing with the challenges on provision of health services for migrants and cross-border population have been emphasized on the development of health and health-related policies to solve the obstacles at national level, such as to integrate primary care services or community-based health care provided at migrant community health centers with support and assistance of migrant health workers and migrant health volunteers to be a part of existing universal health insurance system for migrant workers and cross-border population, and the development of bilateral and multilateral international cooperation to mobilize efforts and collaboration in order to reduce negative impacts to the overall economic and social development of the region.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Health Service design in Primary care under situation Covid-19 disease: Study case of district Yarang, Pattani Province 
abstract:The project, Health Service design in Primary care under situation Covid - 19 diseases Study case of district Yarang, Pattani Province., aimed to stimulate health personnel to recognize the importance of primary health care system and to design their own service delivery responding to unique context complexity at local level in the southern part of Thailand. The project consists of 2 processes as followed. 1) Self-review of Pattani’s health personnel in primary care system to respond to recommended procedures regarding the COVID - 19 epidemic control in communities. The procedures were based on the WHO primary care framework, a framework with community network partners and the analysis of the complexity of the epidemic situation. There has been a response to the government policies and agreements at the area level in order to achieve 3 goals, namely 1) Safety of personnel and provider, 2) Strong community for disease management, and 3) Effective disease control. As a result, target personnel could understand the complexity of the problems and be motivated to develop health service to respond problems that arise. At the same time, the researcher realized that the policy imperative to the main responsible agencies at the national level. There should be preparation and readiness of the whole structure, specific budgets and personnel to cope with future outbreaks and response to chronic disease problems that may require a different management approach. 2) Target personnel development for new health service design by using “Design Thinking” process. The result of the development was a new working design and service system responding to complex health problems at the local level in 4 issues: 1) Anemia problem in pregnant women, 2) Expanding the services access to vulnerable groups, 3) The development of rehabilitation service for stroke patients (Intermediate care), and 4) The development of health service systems for uncontrolled hypertension and diabetes patients. Regarding the new delivery processes design, it was found that the health personnel placed greater emphasis on the primary health care system and the patients were more confident about receiving the service, as evidenced by the co-rehabilitation of 21 stroke patients revealed that 18 patients (85.71%) had increased ADL levels and improved clinical outcomes in a sample of 22 pregnant women with anemia were able to manage the problem in 14 cases (66.66%) without anemia. In addition, all four services were prepared in order to response to the potential recurrent of COVID-19 epidemic in Pattani.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Impact of Molecular Subtyping in Muscle Invasive Bladder Cancer by mRNA expression clustering on Predicting Survival and Response of Treatment 
abstract:Molecular subtyping of muscle-invasive bladder cancer (MIBC) predicts disease progression and treatment response. However, present subtyping techniques are based primarily on transcriptomic analysis, which is relatively expensive. Subtype classification of protein levels by immunohistochemistry (IHC) are more affordable and feasible to perform in a general pathology laboratory. Recent data demonstrated that GATA3, CK20, CK5/6, and CK14 protein levels were correlated with MIBC molecular subtypes. We aimed to evaluate the correlation of those IHC markers with survival outcomes after radical cystectomy in Thai patients. Moreover, we aim to evaluate molecular subtypings by mRNA expression analysis. We evaluated the IHC-based subtypes in MIBC, as classified by GATA3, CK20, CK5/6, and CK14 expression in 132 MIBC patients who underwent radical cystectomy followed by adjuvant chemotherapy (2008–2016). All individual markers and clinicopathological parameters were analyzed against treatment outcomes after radical cystectomy and some selected tissues were sent for whole transcriptome sequencing and clustering from mRNA expression. The result showed that the mean patient age was 65.6 years, and the male to female ratio was 6.8:1. Positive IHC expression rates of GATA3, CK20, CK5/6, and CK14 were 80.3%, 50.8%, 42.4%, and 28.0%, respectively. The 5-year overall survival (OS) was 27.0% (95% confidence interval (CI) 19.6%–35.0%). Only GATA3 and CK5/6 were significantly associated with survival outcome (log-rank p-values = 0.004 and 0.02). GATA3 and CK5/6 were then used to establish subtypes, which were luminal (GATA+ and CK5/6−, 38.6%), basal (GATA− and CK5/6+, 12.9%), mixed (GATA+ and CK5/6+, 37.9%), and double-negative (GATA− and CK5/6−, 10.6%). Patients with the mixed subtype had a significantly better 5-year OS at 42.8%, whereas patients with the double-negative subtype had the worst prognosis among the four groups (5-year OS 7.14%). In the multivariable analysis, lymph node status and subtype independently predicted survival probability. The double-negative subtype had a hazard ratio of 3.29 (95% CI 1.71–6.32). In conclusion, subtyping using GATA3 and CK5/6 was applicable in MIBCs, and patients with the double-negative subtype were at the highest risk and may require more intensive therapy and mRNA subtyping by mRNA expression must showed the significant relationship with survival rate.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: The study of situations and recommendations on health service system for vulnerable populations during the Coronavirus Disease 2019 (COVID-19) outbreak in Thailand 
abstract:The outbreak of Coronavirus disease 2019 (COVID-19) has a massive impact on health and well-being in all populations especially the vulnerable populations. Due to their vulnerability and limited opportunity to access health services, vulnerable populations have a greater health risk compared with other populations. Despite existing universal health insurance for all populations in Thailand including Universal Health Coverage Scheme (UCS), Civil Servant Medical Benefit Scheme (CSMBS), Social Security Scheme (SSS), and Health Insurance Card Scheme (HICS) for migrant workers and their dependents, there remain some uninsured populations. Therefore, this study aimed to provide policy recommendations to improve the health systems for vulnerable populations in Thailand during the COVID-19 pandemic. Both quantitative and qualitative studies were performed. Firstly, the situation of access to health services among vulnerable populations in Thailand during COVID-19 was studied by using the hospital service records of the Ministry of Public Health (MOPH) (43 folders), a secondary data, from National Health Security Office (NHSO) from January 2020 to June 2021. Secondly, document review regarding access to health services for vulnerable population. s. Lastly, in-depth interviews and focus group discussions on relevant stakeholders were performed to develop recommendations for improving health services for vulnerable populations. In this regard, a total of 39 participants including policymakers, staff responsible for taking care of vulnerable populations, and vulnerable populations were selected by purposive sampling and snowball sampling. The findings demonstrated that vulnerable populations the COVID-19 screening test utilised by vulnerable populations accounted for approximately 1,154,355 records (included all insurance schemes) during January 2020 – June 2021. Focused only on the UCS, there were COVID-19 screening tests in total 939,444 times. The number of visits of vulnerable people receiving COVID-19 tests and treatment in both outpatient (OP) and inpatient (IP) care was about 9,288. The number of deaths of vulnerable populations due to COVID-19 was 216.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Developing a Fast Healthcare Interoperability Resources (FHIR)-Based Electronic   Medical Records for Acute Ischemic Stroke Patients 
abstract:Electronic health data plays a prominent role in the delivery of patient care. It depends upon the management of vital information exchanged among healthcare providers, as such can lead to more appropriate decision-making and improved quality of care and research. Currently, the lack of adequate health informatics standards in Thailand is a major challenge for data stored and sharing. Fast Healthcare Interoperability Resources (FHIR) is a globally important health data standard for information modeling and transfer. This study, thus, explored 1) how data schema of Acute Ischemic Stroke Care Record Summary (AISCRS) can be modeled on FHIR specification; and 2) in how far the data elements can bind with standard medical terminologies (SMTs). The study employed a data mapping technique for information modelling by identifying and mapping corresponding elements between data models, i.e., AISCRS, FHIR, and SMTs. The results demonstrated that the entire content of the AISCRS can be modeled using FHIR. 96% of the content mapped onto core elements, and 4% of the content were modelled as extensions. Furthermore, the FHIR data schema comprehensively supported medical terminology system binding, including SNOMED CT, LOINC, ATC, TMT, HL7, and ISCO-08. Therefore, FHIR proved a suitable model for the entire AISCRS.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Completeness and Correctness of the 52-File Standard Datasets for Value-Based Healthcare Indicators in Diabetes Mellitus 
abstract:The development of integrated information system (registration and utilization information system as a repository for common use) for health should be based on the conceptual framework of value-based healthcare (VBH). The proper structural measures compatible with patient database along with the completeness and accuracy of the database are the focus of the present study to monitor and evaluate the VBH. The study of diabetes based on the 52-file standard datasets expected to see a high number of Thai people with diabetes that caused high costs and disease burden. The present study employed mixed methodologies to study the appropriate indicator structures in relation to the patient databases. The quantitative data from October 2017 to September 2018 from the primary care units in Lopburi (A) and Phetchabun (B) were analyzed. The results showed that A had 170 patients with 24.1-97.1% data completeness and 92.3-100% data accuracy; while B had 8,836 patients with 0-81.4% data completeness and 67.9-100% data accuracy. The qualitative research based on interviews with 10 relevant workers in the PCUs led to similar conclusion that duplicate data and wrong data formats were common data errors and affected the monitoring of quality of the full range of services. The development of the continuity of care and outcome reporting system would help improve the completeness and accuracy of health
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Cost per Admission Day of Intermediate Care among Patients Diagnosed with Cerebrovascular Diseases in a Tertiary Hospital 
abstract:This research aimed at examining costs of intermediate care among patients with cerebrovascular diseases hospitalized in a tertiary hospital in fiscal year 2018. This study was a cross-sectional descriptive study collecting data from July to December 2019. Seventy patients with cerebrovascular diseases were recruited accruing 179 admissions and 1,417 admission days, average admission day per case equaled to 7.9 days. Research findings showed that 71.4% of participants were the universal coverage scheme (UCS) beneficiaries, 25.7% were beneficiaries of the civil servant medical benefit scheme (CSMBS) and 2.9% were members of the social security scheme (SSS). The full internal cost of intermediate care was approximately 2,293,622 baht. The highest cost was routine service cost (RSC) at 1,484,988 baht, followed by medical care cost (MCC) at 807,472 baht, while the capital cost (CC) was the lowest at 1,163 baht. Among different health insurance schemes, variation of full cost of each health scheme was marginal i.e. the UCS at 1,604, the CSMBS at 1,656, and the SSS at 1,716 baht per admission day. The full external cost of intermediate care among patients with cerebrovascular diseases was 4,722 baht per case consisting of 4,182 baht of direct non-medical cost per case, and 350–1,490 baht per case for opportunity cost. Cost analysis using cost-bearer criterion into internal costs borne by providers and external costs borne by patients/families could guide health service planning integral to efficient financing at the heart of health system strengthening to improve health of the population, and achieve equitable access to essential health care service with efficient use of health resources.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Orthodontic Fee Schedule and Reimbursement of Cleft Patient Treatment 
abstract:National Health Security Office (NHSO) lump sum pays a service unit for orthodontic treatment 48,000 baht per cleft patient’s lifetime even the orthodontic treatment is ongoing. When some patients have to relocate and be treated at other service units, they are charged for the remaining treatment. This descriptive cross-sectional study aimed to perform costing based orthodontic fee and payment schedule. Itemized full cost was calculated according to activity-based costing. Two workshops with dental personnel of 15 regional hospitals in 9 health regions were conducted to collect data on itemized service time, and the material and non-drug medical supplies of the budget year 2020. The national data on average renumeration per minute of specialist dentist, dental technician and dental assistance; and depreciation cost of building and dental equipment were obtained from the Ministry of Public Health. The indirect cost was added at a 20% of the total direct cost and the future development cost was a 25% addition on the full cost. Itemized dental lab fee (if any) was finally added to be the final fee for reimbursement from the government payer. The study was performed during February to December 2020. The full cost and final fee of orthodontic treatment were 47,311 and 56,320 baht per patient lifetime. The payments of 3 treatment phases conforming with cost of dentition by age were 3,583 (for primary dentition of pre-school age) 18,158 (for mixed dentition of primary school age) and 34,580 baht (for permanent dentition of secondary school age). If based on final fee, the required budget for reimbursement should increase by 8,320 baht per patient lifetime. According to the 2013 NHSO’s 48,000 baht rate, the payments should be 3,054; 15,475 and 29,471 baht respectively.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Outcomes of Home Health Care in Patients with Schizophrenia by Multidisciplinary Team of Donmoddaeng District Health Service Network in Ubonratchathani 
abstract:Background and Rationale: Treatment discontinuation and medication non-adherence are critical problems in caring patients with schizophrenia; this could cause recurrence and serious consequences of schizophrenia. A multidisciplinary team in Donmoddaeng district, Ubonratchathani province developed a home health care, proactive approach, to promote patient care and treatment continuity. This study aimed to determine outcomes of home health care in patients with schizophrenia provided by a multidisciplinary team in Donmoddaeng district, Ubonratchathani province. Methodology: A randomized controlled trial was conducted in 60 schizophrenia patients (30 in study group and 30 in control group). All patients received usual care at the hospital. The patients in the study group received three visits of home health care by a multidisciplinary team and brief motivation counseling by a pharmacist. This study was a 6-month trial, run during July – December 2019. Clinical outcomes and quality of life were measured together with problem-solving results and patients’ satisfaction pertaining to home health care. Results: Most patients were male (study group 60% vs. control group 63%), aged above 30 years (93% vs. 67%), single (47% vs. 63%), with primary school education (67% vs. 53%), employed (57% vs. 57%), living with family (77% vs. 90%) and had disease longer than 5 years (73% vs. 53%). After brief motivation counseling, the follow up rate with doctor increased from 87% to 100% in month 1 and 2 (p = 0.043), the medication compliance rate also increased from 87% to 100% in month 1 and 2 (p = 0.043). Patients were very satisfied with home health care (4.37±0.49). At month 6, the recurrence rate of schizophrenia in the home health care group was 0% vs. 17% in control group (p = 0.020), and hospitalization due to the recurrence was 0% in the home health care group vs. 13% in the control group (p = 0.038), with average length of stay of 0 day vs. 0.60 ± 1.85 day (p = 0.040). No significant difference in quality of life scores was found (11.00 ± 10.86 vs. 9.50 ± 9.13, p = 0.7). Conclusion: Home health care by multidisciplinary team in patients with schizophrenia was effective. Healthcare facilities should support this proactive approach in order to improve efficiency and effectiveness of schizophrenia patient care.