plueme/wizJson huggingface dataset:
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Comparison of Superficial Surgical Site Infection between Delayed Primary versus Primary Wound Closure in Complicated Appendicitis : A Multicenter Randomized Controlled Trial 
abstract:Importance: Superficial surgical site infection (SSI) is common in appendectomy for complicated appendicitis. Delayed primary wound closure (DPC) is preferentially used over primary closure (PC) but its efficacy is still controversial. Objective: To compare superficial SSI rates between DPC and PC for complicated appendicitis. Design, setting, participants: A multicenter, randomized controlled trial of complicated appendicitis, involving 607 adult patients from 6 hospitals in Thailand between November 2012 to February 2016. This included cases of gangrenous appendicitis, as well as rupture. Intervention: Patients were randomized to PC (i.e., immediately wound closure after operation) or DPC (i.e., wound closure at postoperative days 3 to 5). Main outcome and measure: Superficial SSI, as defined by the Center for Disease Control criteria. Secondary outcomes included postoperative pain, length of stay, recovery time, quality of life and cost of treatment. Results: Among 303 and 304 patients in the PC and DPC groups, 5 and 4 patients were lost follow up respectively, leaving 300 and 298 patients for intention-to-treat (ITT) analysis. The superficial SSI rate was lower in the PC than DPC group (i.e., 7.3% (95% CI: 4.4, 10.3) versus 10% (6.6, 13.3)) with a risk difference (RD) of -2.7% (-7.1%, 1.9%). Protocol violations occurred in 15 patients (i.e., 9 in PC and 6 in DPC groups).  RDs for per-protocol and as-treated approaches were respectively -1.9% (-6.5%, 2.6%) and -1.1% (-5.6%, 3.4%). In addition, a counterfactual approach using instrumental-variable analysis yielded a RD of -3.6% (-8.3%, 1.1%).  Postoperative pain, length of stay, recovery times, and quality of life were not significantly different between groups with corresponding RDs of 0.3 (-2.5, 3.0), -0.1 (-0.5, 0.3), -0.2 (-0.8, 0.4), and 0.02 (-0.01, 0.04). However, costs for DPC were 2083 (1410, 2756) Baht higher than PC (~$60 USD or 56 euros). Conclusion and Relevance: Superficial SSI rates were slightly lower for PC than DPC groups, although this did not reach statistical significance. Costs were modestly but statistically significantly lower for the PC group. Trial Registration: clinicaltrial.org Identifier:  NCT01659983
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: The study of genotype of Leptospira in patient, companion animals, carrier animals, wild animals and environment in Nan province and experimental infection of human isolate leptospirosis in cattles and pigs 
abstract:Nan province is an index area of leptospirosis study model in Thailand where provided the evidence linkage between human and rodents but lack of a data in domestic animals such as cattle, pigs and dogs. This study aimed to detect and isolate the pathogenic Leptospira spp. from domestic animals by serological assay, Microscopic Agglutination Test (MAT), molecular assay, rrs nested polymerase chain reaction (PCR), and culture. Identification Leptospira species by near-full length 16S rRNA sequencing, determination Leptospira genetic relationship and clonality by constructed phylogenetic tree and MLST and PFGE from a total of 525 sample of bloods and urine from animal in Nan province during 2013 to 2015. Overall, the seroprevalence to leptospiral detection by MAT was 8.09% (95% confident interval (CI) 4.38-11.74). The major leptospiral serogroup was Shermani and the minor serogroup were Sejroe and Tarassovi, respectively. By rrs nested PCR, 7.42% (95% confident interval (CI) 5.18-9.66) of samples were positive to pathogenic Leptospira spp.. DNA sequencing and phylogenetic analysis found the positive samples were clustered in a branch of L. interrogans, L. weilii and unidentified Leptospira spp.. We could successfully isolate four leptospires from dogs and identification Leptospira species by near-full length 16S rRNA sequencing revealed L. interrogans (n=2) and L. weilii (n=2). In molecular epidemiological study by MLST, we found novel sequence type (STs) of Leptospira; ST26 and ST33 for L. interrogans and ST94 for L. weilii. ST26 and ST33 was a singleton without clonality to Leptospira species in database. ST94, however, was a putative founder of ST193 and ST183 isolated from human leptospirosis in China and Laos. Our study provides an important epidemiological information of animal leptospirosis in an endemic area that may be continually useful for disease control and prevention strategies.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Implementation of One Health Concept in Lowering of Human Streptococcus suis Cases in Chiang Mai 
abstract:This study aimed to explore the epidemiological information of Streptococcus suis (S. suis), either in pigs and human. Those information was used to find the appropriate method to reduce the number of S. suis infection in human. The tonsil swab samples from sows and fattening pigs, pork from pig slaughter houses and pork in wet and super markets in Chiang Mai province were collected for S. suis culture. Moreover, demographic data, education attitude and risk factors data from 35 S. suis infection patients were collected. The results indicated that from 43 farm, sow samples from 13 farms were detected S. suis (30.23%). In fattening pigs, S. suis was detected in 57 farms from 111 farms (30.23%). Pork sample from pig slaughter houses and pork in wet and super markets were detected S. suis 26 from 119 (21.85%) and 5 from 50 samples (10.00%), respectively. S. suis type 2 were found in 1 pork sample from pig slaughter houses and 1 pork sample from wet market. The virulence gene, including gdh+,arcA+,mrp+,thrA+ and sly+ were detected from those sample. The data in human showed that S. suis patients were male more than female. All of them had underlying diseases and always drank alcohol. They had the history of raw pork or unsure well cooked pork before showed clinical signs. Nine patients (27.71%) showed deafness and trend to be permanent deafness. This study indicated that even though pigs is the important carrier of S.suis and the agent can transmit to human via slaughter process, the consuming behavior is the key factor that effect S. suis in human.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: A study of mutated Burkholderia pseudomallei isolated from Lower northeastern part of Thailand 
abstract:Burkholderia pseudomallei are a causative agent of melioidosis and ceftazidime is the drug of choice for treatment. However, the motility rate is high in endemic areas. This study aimed to investigate an incident of the blaPenA and blaOXA mutation and tendency of β-lactam antibiotics in B. pseudomallei from patients admitted to hospitals in lower North-East Thailand. A total of 1,340 isolates of patients with B. pseudomallei admitted to Sappasitthiprasong Hospital, Sisaket Hospital, and Amnatcharoen Hospital between January 2013 and February 2015 were determined for antimicrobial susceptibility by standard disk diffusion and minimum inhibitory concentration (MIC). The conventional polymerase chain reaction (PCR) was used for the detection of blaPenA and blaOXA in β-lactamase genes with the specific primers. Almost all of the clinical isolates of B. pseudomallei were susceptible to ceftazidime, piperacillin, cotrimoxazole, cipofloxacin, and imipenem by the standard disk diffusion test. Cefatzidime MIC was ≤1-≥32 μg/ml and imipenem MIC was ≤0.5-≥8 μg/ml. MIC50 and MIC90 of ceftazidime were 2 μg/ml and 4 μg/ml respectively, and MIC50 and MIC90 of imipenem were ≤0.5 μg/ml and 1 μg/ml respectively. The conventional PCR followed by gel electrophoresis revealed that only Class D beta-lactamase gene or oxa was detected in all DNA samples isolated from B. pseudomallei. DNA sequencing followed by amino acid analysis and comparison by the bioinformatic approach found that all translated amino acid sequences showed 100% identity to those reported in the National Center for Biotechnology Information (NCBI) database. This result demonstrated that there were no any mutations in oxa gene in B. pseudomallei. PenA gene was not detected in all DNA samples. However, the penA gene with the length of 300-500 bp was detected from the beginning of this study. It is suggested that this amplified product be sent for sequencing to confirm that it is penA.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Cost-utility of arthroscopic knee surgery for anterior cruciate ligament with or without meniscus injury in an M1 general hospital in the 7th Health Region 
abstract:Health Region 7th has developed strategies to build up and enhance capacity for medical services in orthopedic at the M1 level hospital. This study was aimed to assess cost utility of arthroscopic knee surgery in patients who had anterior cruciate ligament injury with or without meniscus injury at M1 hospital level as compared to the operation performed at only the provincial hospital level. The present study was based on decision tree analysis with the time horizon of 1 year using a societal perspective. The primary data collection was performed to obtain the following key variables: waiting time, complication rate, return to sport outcome (up to 1 year), direct medical cost, direct nonmedical cost, indirect cost, and utility (EuroQoL-EQ-5D-5L). The study sites included Sirindhorn Hospital (M1 level) and Khon Kaen Hospital (provincial hospital). The training cost and cost of instruments were 99,328 Baht. At Sirindhorn and Khon kaen hospitals, proportions of patients undergone surgery within 2 months were 93% and 25%, and the averages of waiting time were 1.03 ± 0.67 and 4.3 ± 3.0 months, respectively. The complication rates were similar of 7%. All patients with or without complications could return to sport within 1 year. Utilities at baseline, after surgery, 3, 6, 12 months thereafter were 0.66±0.15, 0.77±0.22, 0.92±0.07, 0.93±0.06 respectively. Under the timeframe of 1 year, direct medical cost, direct non-medical cost, and indirect cost for one case were 19,215, 7,488, and 1,479 Baht at Sirindhorn Hospital and 19,413, 7,888, and 1,538 Baht at Khon Kaen Hospital. For one case, total costs were 31,493 and 28,839 Baht, and quality-adjusted life years were 0.91 and 0.85, respectively. An incremental cost effectiveness ratio was 41,058 Baht/Quality adjusted life year. In conclusion, arthroscopic knee surgery for anterior cruciate ligament injury at M1 hospital level could reduce waiting time and was cost effective as compared to the operation performed at the provincial hospital level. The complication rates were similar and relatively low. All patients with and without complications in both hospitals could return to sport within 1 year. The policy recommendation proposes that provision of orthopedic services at the M1 hospital level should be promoted for the procedures that complication rates were similar and relatively low in both levels, complications do not lead to the final clinical outcomes, post-treatment utility outcome would increase by 0.24 (EQ5D 5L), and waiting time should not be greater than 2 months. The procedure as such would be cost-effectiveness if the initial program cost is about 662 Baht per one case.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Progression and outcomes of CKD in Thai SEEK population 
abstract:Chronic kidney disease (CKD) is one of the major public health problem in Thailand. The Nephrology Society of Thailand was granted the community-based cross-sectional survey study using stratified-cluster sampling method to represent population from all region of Thailand called Thai SEEK (Screening and Early Evaluation of Kidney Disease) study during 2007 to 2008. The overall prevalence of CKD from Thai SEEK was 17.5% which increased awareness of CKD burden and lead to deliver strategic planning for CKD prevention and management programs. However, study about the natural history of CKD progression, particularly among Asian and Thai population which might useful for the estimation of health cost and strategies prioritization for slow CKD progression stills limited. Moreover, we still lack of information of the incident of CKD using a standardized method for GFR estimation in representative Thai adult populations. So the research committee of The Nephrology Society of Thailand was conducted this follow-up study from Thai SEEK population.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Improving the quality of life of people with disabilities by using the rehabilitative devices and assistive devices from local wisdom 
abstract:This research aims to identify and disseminate the local wisdom knowledge on equipment for people with disabilities and develop care systems for people with disabilities by using the rehabilitative devices and assistive devices from local wisdom. There were 2 phases in this research; phase 1: find, collect, analyze and disseminate information on the disabled equipment. The data was collected by quality of life questionnaire, the Barthel Activities of Daily Living, data recorder, and interview guideline with 70 disabled people and families with disabilities in Phitsanulok Province. Phase 2: development of care systems for people with disabilities by using the rehabilitative devices and assistive devices from local wisdom
within stages of action research. The data was collected by quality of life questionnaire, Barthel ADL index, group discussion, interview, and brainstorming guideline from 48 of 1) District Health Officers 2) District Sub District Health Officers 3) Community Leaders 4) Sub District Administration Officers 5) Volunteers 6) Village Health Volunteers 7) Disabled People And 8) families of PWDs. Content analysis was used analysis in qualitative data. Frequency, mean, percentage, median, deviations, and Paired t-test were used analysis quantitative data. The results found that 1) there were 53 the rehabilitative devices and assistive devices from local wisdom. The security and be careful in how to use the device
were advised. 2) The development of care systems for people with disabilities by using the rehabilitative devices and assistive devices from local wisdom was found that the system consisted of two levels, namely, the support of the district level, 1) vision and goals, 2) the management center, and 3) the development of human resources for the care of the disabled. 4) supporting budget 5) The Disability Resource Center 6) providing 24-hour for counseling 7) supporting by health organization administrator and the prefect. The process of caring for people with disabilities at the sub-district and community level consisted of: 1) assessment of disability condition and ability for finding the need 2) coordinate with the community health center of the hospital for plan 3) think and design the production of
equipment to care for people with disabilities; 4) physiotherapists to verify academic
accuracy and safety; 5) take care of people with disabilities at home; 6) develop knowledge between carry out of caregiver. 7) publish the work on the line group and
8) evaluate the use of the equipment. The results of the development of the system
found that the quality of life of the disabled and the movement of people with
disabilities improved.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Development of Slope Index of Inequalities in the Use of Public Health Services by Population in Health Regions 
abstract:For an analysis of an inequality in health service use across areas, a recommended measure is
slope index of inequalities (SII). The SII captures area variations in users of health services as associated
with total population in the areas ranked by a descending order by health service use. In practice, a
binary outcome, such as use vs. no use, measured at an individual level needs to be aggregated at
the area level in terms of proportion of populations who were the users. To account for uncertainty
due to sampling, the SII could be estimated statistically using linear regression analysis. This paper
used the data in 12 health regions, excluding Bangkok from Health and Welfare Survey in 2015, the SII
revealed statistically significant inequalities in the use of health services from public facilities for both
outpatients and inpatients across 12 regions. The Universal Coverage Scheme population showed a
lower extent of inequalities in health service use than Civil Servant Medical Benefit Scheme.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: How Many NCD Patients Have Risky Health Behaviors?: Report from Health and Welfare Survey 
abstract:Non-communicable Diseases (NCDs) are a major public health problem. NCDs can be prevented by reducing risk factors such as smoking, alcohol consumption, sweetened beverage consumption, and inadequate physical activity. For a more effective solution, the ordinary NCDs treatment should be adopted, as well as the preventions of the NCDs risk factors. This study aimed to report the situ¬ation of NCD patients’ risk behaviors in Thailand. The secondary data from the 2015 National Health and Welfare Survey was adopted for analysis on NCD patients aged 15-65 years who had cardiovascu-lar disease, diabetes mellitus, cancer, or chronic respiratory disease. The study showed that risk be¬haviors in smoking (10.7%), alcohol consumption (16.8%), sweetened beverage consumption (51.34%) and inadequate physical activity (68.8%) were still occurring among NCD patients. The evaluation also suggested that while the male group had increased risk behaviors of smoking and alcohol consump¬tion than female group, however the latter had increased risk behavior of sweetened beverage con¬sumption and inadequate physical activity. By considering the socio-economic characteristics of the NCD patients, the study found that the majority of NCD patients consisted of ageing and adult workers in agricultural and low-skill industrial sectors, and those who lived in outer urban area. It was further noted that different economic status was not a significant factor in affecting the NCD risk behaviors. The findings confirmed that Thailand’s NCD patients had high risky health behaviors and health pro-motion activities were highly recommended for reversing these risks.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: How Much of Energy Expenditure from Physical Activity and Sedentary Behavior of Thai Adults: The 2015 National Health and Welfare Survey 
abstract:This study aimed to determine the amount of energy expenditure from moderate to vigorous intensity physical activity in 3 domains (occupation, transportation, and recreation), and sedentary behavior of Thai adults disaggregated by subgroups of participants. The data of 113,882 Thai adults aged 15 and above from the 2015 National Health and Welfare Survey conducted by National Statistical Office were analyzed using descriptive statistics and two-part model. The results showed that the average energy expenditure from moderate to vigorous intensity physical activity by 3 domains was 1,728 metabolic equivalent of task-minute/week. The energyexpenditure from work domain was the highest (1,113 MET-minute/week), followed by transportation (286 MET-minute/week), and recreation (230 MET-minute/week), much lower than the results from other international studies. The energy expenditure in sedentary activities was also high at 774 MET-minute/week. The energy expenditure from 3 physical activity domains was higher in males and adults (aged 30-44) living in rural areas including farmers and laborers, and those who had lowest education and income levels, without underlying diseases, and self-reported with lower health problem status. These subgroups with higher energy expenditure from physical activity also reported lower energy spent sedentary. Our findings will benefit to the national policy development on physical activity by transforming energy expenditure in sedentary activities to other physical activity domains. For example, office-based employee spent low energy expenditure from work domain should be encouraged to the standing break or walking every hour of sitting, using stairs instead of elevator, or using public transport, walking or biking to workplace. In addition, we urge for the improvement of national physical activity to be more accurate and conducted continuously.
location: nan, 'Thailand 
year: 2017 source: HSRI 
title: Self Medication among Thai People by Buying Medicines from Community Pharmacy 
abstract:Universal Health Coverage aims to increase access to essential health services to minimize household health expenditure. However, a number of people still do not use services provided under the Universal Health Coverage. These people prefer self-medication by buying medicines from community pharmacy. This research aims to study characteristics of these people and the expenditure for self-medication. Descriptive study design was used. The 2015 Health and Welfare Survey data conducted by National Statistical Office containing 139,848 individual persons were analyzed. Based on the survey, an individual who had at least one time of illness that did not require hospitalization within the last month was identified and then the data about self-medication and out-of-pocket payment were collected. Sampling weight was applied using appropriate statistics to make sure that the dataset could represent all Thai population in all 13 health regions. Findings showed that 27.2% of those who had at least one time of illness that did not require hospitalization had self-medication. The percentage of self-medication of region 7 (37.7%) was the highest compared to other regions. By scheme, the highest rate of self-medication was found in the social security members (35.0%). Rural population had 10.4% more self-medication than urban population. Most of the people who used self-medication strategy were in the lowest quintile and had no underlying diseases. Their symptoms included common cold/cough and running nose (44.4%). The median cost of self-medication was 60 Baht per visit. For patients with underlying diseases, cost was as high as 120 Baht per visit. Factors associated with self-medication should be examined in further studies. Quality development of community pharmacy should be implemented because community pharmacy is still the major source of self-treatment.