plueme/wizJson huggingface dataset:
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Research and Development of Computerized Program to Prevent Therapeutic Duplicate Prescription in Mahasarakham Hospital 
abstract:Background & Rationale: Duplicate medication is irrational drug use that can cause adverse drug events to patients and wasteful health expenditure. There have been a limited number of studies on duplicate prescribing in Thailand. The objective of this study was to develop a computer software to prevent therapeutic duplicate prescription and to determine its effects in Mahasarakham Hospital. Methodology: This research and development comprised three parts. Part 1 described characteristics and magnitudes of duplicate drug prescribing in the hospital using electronic database of 12 drug groups (39 drug items) during 1 October 2018 – 30 September 2019. Part 2 developed a computer software based on results of part 1 and implemented the software in November 2019. Part 3 examined effects of the software by comparing proportions of duplicate drug prescriptions during, before (November 2017 – April 2018) and after software implementation (November 2019 – April 2020). Results: Of total 218,179 prescriptions, 818 duplicates (0.37%) were found, of which 576 (0.26%) were duplicate medication at the same therapeutic groups and 242 (0.11%) at the same drug item. Moreover, 530 duplicates (0.24%) were detected in the same prescription and 288 duplicates (0.13%) detected in the same patient. The highest duplicate medication rate was found in the gastric secretion inhibitors group (378/36,495 prescriptions, 1.04%), followed by antihistamine (130/13,433 prescriptions, 0.97%) and NSAIDs (184/29,783 prescriptions, 0.62%). These duplicates costed around 19,740 – 79,591 baht/year. The software detected any duplicate medications prescribed in the same therapeutic drug, same patient and same day and alert prescribers/ pharmacists for clarification. After software implementation, the duplicate drug prescribing decreased significantly from 0.27% (266/100,367 prescriptions) to 0.08% (75/95,350 prescriptions) or a 70.3% reduction (OR 0.296, 95%CI: 0.226-0.384, p < 0.001). The excess healthcare cost declined by 4,098 – 18,360 baht/6 months or 8,196 – 36,720 baht/year. Conclusion: The developed computer software was effective in preventing duplicate prescription and reducing unnecessary healthcare cost. Future studies should determine duplicate drug prescription and prevention program at national level to support rational drug use and reduce healthcare cost in Thailand.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Situation of Employing Retired Nurses in Hospitals under the Permanent Secretary Office of Ministry of Public Health 
abstract:The cross-sectional survey research was conducted to study the situation of employment of retired nurses in hospitals under the Permanent Secretary Office of the Ministry of Public Health. The data on employment of retired nurses were surveyed from regional hospitals, general hospitals and community hospitals during fiscal year 2019-2020. The results show that there were 31 of 116 regional and general hospitals (26.7%) that employed retired nurses in 2019. In the fiscal year 2020, there were 28 hospitals (24.1%) that employed 162 retired nurses. For community hospitals, 20 of 780 hospitals (2.6%) employed 32 retired nurses in 2019 and reduced to 18 hospitals employing 20 retired nurses in 2020. Hospitals in the central and the eastern regions had the highest employments of retired nurses. There were 2 types of job characteristics (nursing work and non-nursing work such as health information management and health record). The pattern of employment was either full-time or part-time. Many payment arrangements were reported, such as daily payment (at a rate of 600-800 baht a day), monthly payment, and performance compensation. However, all payments were based on the regulations of the Ministry of Public Health. As for community hospitals, 20 hospitals employed 32 retired nurses (2.6%) in 2019, and reduced to only 18 hospitals employing 20 nurses (2.3 %) in 2020. During the fiscal year 2019-2020, hospitals in the central and the eastern regions (Health Region 4, 5 and 6) reported the highest employment rate than other regions. Regarding the 2 types of employment: 1) the nursing work employment was reported at the outpatient department, inpatient wards, special clinics and antenatal care clinics, accident and emergency department, central dispensing unit, breast feeding clinic, orthopedic department, primary and community care unit, and diabetes clinic. 2) The non-nursing work employment was reported in other departments such as in the medical records audit, the outreach health check unit, the patient complaint services, the health insurance center, and the public relations. The monthly payment was approximately 13,000-20,000 baht a month. The time-based payments varied as 100 baht an hour for working in the central supply unit, 80 baht an hour for other units, 450-600 baht a day for the patient complaint services, and the public relations, respectively. The results revealed the situation of employment of retired nurses, the characteristics and the patterns of employment. These results should be useful for policy development on human resource planning. Moreover, employment of retired nurses at different levels of health sectors should be further researched.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Clinical Outcomes and Physical Therapy Indicators for Improving Standard of   Physical Therapy Service: A Review of Systematic Review 
abstract:This literature review aimed to investigate clinical outcomes and physical therapy indicators in 4 physical therapy fields, i.e. 1) musculoskeletal system, 2) neurological system, 3) pulmonary and cardiovascular system, and 4) pediatrics. Systematic reviews were searched from start to 15 July 2019 in several databases, including PubMed, ScienceDirect, Web of Science, Scopus, and PEDro. Relevant systematic reviews with full report published in English were retrieved. Data from included studies were extracted, analyzed, and synthesized. The results showed that 151 papers were included in this study. Clinical outcomes and physical therapy indicators were categorized into 22 groups. In general, assessing patient’s clinical outcome required more than one clinical tool or form to cover all aspects of patient’s problems, including signs and symptoms, functional ability, and social participation. Most common clinical outcomes and physical therapy indicators used were pain, body movement, functional ability, and quality of life. Physical therapists can apply this information to set treatment goal, planning treatment program, and evaluating treatment progression in order to improve quality of service to patients and to establish goals for service from a multi-professional team.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Physical Activity, Carbon Dioxide Emission and Cost of Transport: A Case Study of Three Communities in Thailand 
abstract:Walking and cycling are common physical activities if performed regularly in daily life will return health, environmental and economic benefits. This study aimed to 1) assess built environments that encourage walking and cycling in communities, 2) assess levels of physical activity and energy consumption, and 3) investigate the amount of carbon dioxide emission and cost of transport. Quantitative method was employed. Data collection techniques comprised direct observation and questionnaire survey in three communities: 1) King Taksin community in Bang Khla district, Chachoengsao province, 2) Suksabaijai community in Mueang Kalasin district, Kalasin province, and 3) Ban Thatsopwaen community in Chiang Kham district, Phayao province. The results showed that King Taksin community had the highest scores on walking, cycling and use of public transport as the community center was close to the district shopping center with a well-managed public transport system. Samples from King Taksin and Ban Thatsopwaen communities had the highest levels of physical activity due to frequent walking and cycling in their daily life. Suksabaijai community had the highest level of carbon dioxide emission from motorcycles and cars, and the highest transport cost as the community center was far from the shopping center with its built environments of having a high-speed road passing through the community center hence discouraged walking and cycling. This study recommends that all agencies promoting physical activity should work with local community in designing built environments and evaluating effectiveness of walking and cycling promotion programs that fit with each community.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Lessons Learnt from Developing and Implementing the National Steps Challenge in Thailand 
abstract:Thailand national steps challenge policy has been developed in 2019 by the physical activity policy development subcommittee according to Thailand Physical Activity Strategy 2018-2030. The policy has been implemented through Thailand Virtual Run Season 1 Fiscal Year 2020 by the Division of Physical Activity and Health, Department of Health, Ministry of Public Health. This article reviewed details of the policy formulation and implementation in order to get deeper understanding on the process of policy development, implementation gaps, and to make further recommendations. Lessons learnt led to deeper understanding on policy formulation at national level that required concurrent assembling of problem, policy, political streams with proper window of opportunity. Policy implementation needed context and situation adjustment for smooth management. Lastly, learning policy gaps from the past could shape better policy implementation in the next stage.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Lessons Learnt from Prevention and Control of COVID-19 Pandemic: A Case Study of Angthong Municipality 
abstract:The world is in the grip of the novel coronavirus or COVID-19 pandemic. Since it was first identified in Wuhan, a city in China at the end of 2019, the disease has rapidly spread to countries around the world. This pandemic is likening to occur once in a century. In Thailand, there were 3,000 accumulative cases from 68 out of 77 provinces. This article reviewed the essence of COVID-19 prevention and control activities by Angthong municipality in Angthong province from 1 February to 12 May 2020 that led Angthong as 1 out of 9 provinces that had no provincial inhabitants infected. The aim of the study was to understand COVID-19 prevention and control highlighting collaboration of community-level stakeholders. Lessons learnt from this study provided an insight on Angthong provincial disease control committee mechanism, the arts of implementation of Angthong municipality, importance of local leadership, and dynamic of daily life shifting of local people for further development on disease control policy at both local and national levels.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Incidence of tuberculosis in difference of CD4 cell count among HIV infected patients receiving antiretroviral treatment and innovative of self-assessment tuberculin skin test for latent TB screening in resource limited settings 
abstract:Background: Tuberculosis preventive therapy (TPT) among HIV-infected patients are not well established in Thailand and may be due to multifactorial reasons. One of the most crucial reasons is because most physicians are convinced that antiretroviral therapy (ART) alone can decrease the incidence rate of active tuberculosis (TB) to the incidence rate of the general population. However, the incidence of TB data among Thai HIV-infected patients on ART is also scant. This information is very important because HIV-infected patients can have latent tuberculosis infection (LTBI) which can later progress to active TB. Therefore, TPT is crucial among HIV-infected patients to prevent active TB. Method: We conducted a cross-sectional, multi-center study in HIV-infected patients from 14 hospitals throughout Thailand between 2009 and 2018. This study compared the incidence of active TB among HIV-infected patients with different CD4 cell count after ART has been initiated. Results: A total of 9,179 HIV-infected patients were enrolled; 442 (4.8%) were diagnosed with active TB after ART was initiated and 8,738 had HIV mono-infection. According to the multivariate analysis, the significant risk factors associated with active TB post ART initiation were the male sex, CD4 less than 350, body weight less than 50 kg and have a prior history of active TB. When ART was initiated at low CD4 cell count, the incidence of active TB was high (Table) compared to the general population (about 150-200 per 100,000 persons-year). Furthermore, when ART was started when the CD4 count was more than 500, the incidence rate of active TB was 2-3 times higher than the general population (394 per 100,000 persons-year). The incidence of TB for the first 2-5 years after ART was initiated decreased to 7,251, 4,083, 2,661 and 1,957 per 100,000 persons-year, respectively. However, these numbers were much higher than the general population in Thailand even when these patients were on ART for many years. Conclusions: The incidence of TB among HIV-infected patients with various CD4 cell count and on ART were high. The incidence of active TB was 2.5 times higher than the general population even when ART was initiated when CD4 was more than 500. For this reason, HIV-infected patients who have had TB infection should benefit from TPT which can decrease the incidence and mortality rate of TB.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: Mobile application development for aging society during health services; A case of the urban   community surround Sirinthorn Hospital, Bangkok 
abstract:Mobile application development for aging society during health services; A case of the urban community surround Sirinthorn Hospital, Bangkok is studied from the study of health situations, aging society and travel problems for health services; A case of the urban community surround Sirinthorn Hospital, Bangkok. They are related to the environment and problems from the deterioration of the body with age and disease by age as making the older person need to receive health services for the older person to have a good quality of life. There are factors related to the service system of the hospital which access to nursing homes public transport and personal vehicles of the older person themselves Including technology to promote travel. The objective of mobile application development for aging society during health services; A case of the urban community surround Sirinthorn Hospital, Bangkok are to develop applications on mobile phones Promote health service travel skills for the older person in urban communities and to assess the effectiveness and efficiency of mobile applications for travel, health services for the older person in urban communities. Methods of conducting the study were quantitative and qualitative research processes. Which is divided into 3 steps which are; Step 1 Design tools, applications and interviews 4 professionals in the production of media applications on communication devices. Step 2 Develop and evaluate application tools by 5 experts in content and technical production Step 3 Develop and evaluate applications for testing and evaluation by selecting older person volunteers from the phase 1 research as develop and evaluate instruments, test and evaluate application tools. By traveling from home to Sirindhorn Hospital, 30 samples. The results of the research on the development of mobile applications to promote health service travel for the older person in urban communities can be concluded that; 1. Factors Related to Getting to Health Services The travel patterns of the older person include 1) The older person group can walk easily 2) The older person group on a wheelchair 3) The older person group sleeps on the bed It is a key factor in mobile application design and development to promote health service travel skills for the older person in urban communities. 2. The convenience of data transmission in the application on the mobile phone. It is a key component used to assess the effectiveness and efficiency of mobile applications to travel to receive health services for the older person in urban communities Mobile application design and development are a factor supporting traveling with ease and quality. Especially map analysis in the information system for convenient travel save traveling time and able to communicate preliminary health information of the older person to the destination sanatorium, prepare the area management which health services that are most suitable for the needs of the older person group.
location: nan, 'Thailand 
year: 2020 source: HSRI 
title: The Efficacy of Fungal Quorum Sensing Molecules in Treatment of Systemic Scedosporiosis focus on common pathogenic Scedosporium species in Thailand (First-year) 
abstract:Scedosporium spp. are human pathogenic fungi causing infections among non-Aspergillus spp. especially in immunocompetent and immunocompromised individuals. Moreover, these pathogenic fungi are highly resistant to standard antifungal drugs whereas effective drugs are highly expensive and give several side effects. Co-treatment drugs have begun to be developed to increase the effectiveness of treatment against Scedosporium infections. One of them is the quorum sensing molecules (QSMs). These QSMs are produced from fungi and play a role in reducing the growth of fungi, especially in the drug resistance group. One of the substances that are increasingly being studied for their role in fungi is Tryptophol (TOH). This research aimed to investigate the role of TOH in the inhibition of fungal infections that were common in Thailand including Scedosporium apiospermum, S. boydii, S aurantiacum, and Lomentospora prolificans. Our study revealed that TOH exhibits an MFC of 8 mM, which is able to stimulate THP-1(Macrophage) and Jurkat cells (T cells) at different time point, 3 and 6 hours post treated respectively. The up regulated cytokines after co-culture with TOH including M1 cytokine , which play a role in the elimination of microorganisms as IL-6 (2, 2.2 folds). T-helper cells cytokines such as คือ IL-17 (4.2, 1.9 folds) and IL-23 (3.8, 2.1 folds), as well as the specific eumycetoma IL-1β (1.7, 2.7 folds), IL-12(3.2, 3.2 folds), IL-37(3.0, 2.6 folds), and IL-35(2.7, 1.9 folds), but not induce apoptosis in both fibroblasts and macrophages. Instead, TOH induced fungal apoptosis as determined using Ethidium bromide/Acridine orange, which corresponded to a 2.2-fold decrease in CARD-9 and a 2.6-fold increase in BCL-2 expressions. After obtaining the laboratory results, our research team began a series of experiments to develop a prototype of neutropenic mouse model of eumycetoma. To produce neutropenic mice, injection of cyclophosphamide at 150 mg/kg were administered. Then, eumycetoma formation was observed in day 3 after intradermal injecting 1x106conidia of Scedosporium spp. at the back of neutropenic mouse. Moreover, our team also developed a prototype emulsion-gel product containing TOH and tested the effectiveness against Scedosporium spp. infection. Our study revealed that the tumor size was reduced after treating with TOH emulsion-gel in infected mice. Moreover, we also expanded our study using an invertebrate in vivo model of Caenorhabditis elegans. Our preliminary results revealed that life span virulence tests and the efficacy of TOH against all four Scedosporium spp. infections exhibited similar promising results to neutropenic mouse model of eumycetoma, suggesting that C. elegans can be used as a powerful alternative model for researchers in microbiology, pathology, and pharmacology in the future.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Automated Surveillance Systems for Assessment, Monitoring, Prevention, and Management Guidelines for Extravasation of Norepinephrine’s Administration from Skin Images using Artificial Deep Neural Network on Smartphone Application 
abstract:Extravasation is a condition of extravasated drug was leaked and potentially damaged the site of infusion. In serious injury cases can cause permanent loss of tissue organ. As a clinical workflow in Thailand, nurses have to define the grading and management of extravasation after intravenous (IV) infiltration. But this procedure also has a limitation by the traditional nurses’ shift schedule, which is make the grading and management of extravasation not continuously by the same person. So, this research project proposes an automated screening of extravasation for surveillance, assessment and monitoring during IV therapy. These included 4 steps: data collection, image labeling, convolution neural network modeling, and application development. Total of 1,084 extravasation images were collected from 5 hospitals: Rajavithi Hospital, Nopparatrajathanee Hospital, Rayong Hospital, Songkhla Hospital, and Thammasat Hospital using our own data collecting application. All images were labeled by three dermatologists by locating the skin lesion and rating the severity of extravasation. If no majority vote of any images, the fourth dermatologist will decide the severity of extravasation. After image labeling, all of image data was used to train a densely connected convolutional neural network (DenseNet-121) model, using five-fold cross validation and transfer learning with data augmentation technique. The results from hold-out testing set have a sensitivity and specificity of 96.30% and 93.90% in normal control images, 80.00% and 88.41 in mild extravasation images, 83.33% and 74.12% in moderate extravasation images, 90.91% and 86.74% in severe extravasation images, and 71.43% and 78.43% in others images, respectively. The results from the model were combined to the final application for surveillance, assessment and monitoring extravasation during IV therapy for providing an ease of extravasation management and increasing the efficiency of clinical workflow to reduce the economic cost spent on patient with extravasation in Thailand.
location: nan, 'Thailand 
year: 2021 source: HSRI 
title: Model Development for Integrated Health Information Technology and Digital Transformation of Diabetes and Hypertension Services in Primary Health Care System in Thailand 
abstract:A series of research projects to develop a model of the information technology system to provide a service of diabetes and hypertension in the primary healthcare system in Thailand has an operational plan for 3 years. In this first year, the study is divided into 2 parts. The first is studying the situation and the need for health information to provide a service for diabetes and hypertension patients/risk groups. Another is developing a model of the information technology system by using standard health information and connecting such information between primary care units and community hospitals in a specific area where there is good data management. The team studied the need for the information on diabetes and hypertension from different groups namely family physicians, patients/risk groups, policy makers and technical officers, and found that they all required the same kind of information including medical records, a display in the form of a time series to reflect and analyze the patients’ behaviors, as well as an effective data transmission system between primary care units and community hospitals which is essential to long-term care and treatment. The team also developed the information technology system model to provide a health service in Kamphaeng Phet Hospital and its primary care units using HL7 FHIR. The program was used to set a standard of data for the users to be able to exchange and access the patients’ information while the patients can also reach their own health records from different places.