anuradha kumari
Senior Medical Writer, Medical + Scientific Strategy at BluPrint Oncology
scientific communication cancer research business strategy & development
* research scientist 10 year experience field cell molecular biology , biochemistry , microbiology ; extensive experience design , development , execution new scientific concept via utilizing diverse range technical skill . * major area expertise : dna damage repair pathway relevant human disease special interest exploiting defect related dna repair mechanism targeting repair-compromised cancer cell . * excellent project leadership management skill ability troubleshoot solve complex scientific problem ; made contribution several inter-institutional multi-disciplinary collaboration . * mentor provide scientific technical guidance junior researcher .
BluPrint Oncology
https://www.linkedin.com/company/bluprint-oncology-concepts
Senior Medical Writer, Medical + Scientific Strategy
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Self-Employed
https://www.linkedin.com/company/self-employed_1074
Science Editor I Writer I Life Science Consultant
* Critically review and present complex scientific/clinical work of the clients and deliver high-quality content by ensuring attention to detail and compliance with different style guides.
* Provide medical publication support to communication companies.
* Volunteered for Science Delivered- Editing scientific material for elementary school kids.
* Familiarity with the following Softwares: Microsoft Office, EndNote, Image J, ImageQuant, AlphaView, Rasmol, FlowJo, WinMDI, DNA Sequencher, Adobe Photoshop, Illustrator, PhotoEdit, AxioVision, i-control™ – Microplate Reader, IncuCyte Zoom Control, Evos Image Analysis, OpenShot Video Editor, Canva, Goggle Doc, and Google Slide
AOIC, LLC
https://www.linkedin.com/company/aoic-llc
Life Science Consultant
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Oregon Institute of Occupational Health Sciences
Senior Research Associate
* Developed a novel drug combination to target breast and ovarian cancer cells (first-author manuscript in preparation) that resulted in a collaborative venture with Vanderbilt group of chemists to synthesize novel drug formulations.  Further, accumulated experimental data to demonstrate an effective delivery of nanoparticles and liposomal drug formulations into target cells (being put together for a grant application).
* In collaboration with the bioinformatics group at the University of Washington, initiated a high-throughput siRNA screening study to identify the repair mechanisms associated with cytotoxicity induced by a well-known environmental carcinogen, formaldehyde (co-authored manuscript in preparation).
* Strong analytical and technical expertise related to prokaryotic and eukaryotic systems led to successful completion of two projects identifying the biological processes critical for limiting formaldehyde-induced cell death. 
1. Revealed a new role for the bacterial uvrD helicase in DNA decatenation following formaldehyde-induced damage (first-author manuscript in preparation).
2. Demonstrated the significance of human Bloom helicase-dependent pathway in formaldehyde-induced DNA damage response (resulted in a first-author publication).
Portland, OR
Oregon Institute of Occupational Health Sciences, OHSU
Postdoctoral Fellow
* Exploited biochemical and microbiological expertise to identify repair enzymes associated with specific DNA-DNA and DNA-protein adducts generated by chemotherapeutic drugs and environmental carcinogens (resulted in three first-author publications). 
1. Investigated the roles of bacterial DNA polymerases II and IV in the processing of N2-N2 guanine crosslinks (generated in response to chemotherapeutic drug, Mitomycin C).
2. Studied how the progression of a DNA helicase enzyme is impacted upon encountering bulky adducts as DNA-protein crosslinks (induced upon exposure to formaldehyde, platinum drugs, nitrogen mustard etc.).
3. Demonstrated the significance of Nucleotide excision repair and Homologous recombination repair pathways in suppressing genomic instability induced by an environmental carcinogen, formaldehyde.

* Contributed to a successful collaboration with the Vanderbilt group of chemists and gained experience in presenting scientific data to a diverse audience.
* Helped secure funds for two NIH grants via making scientific contributions.
Portland, OR
Biochemistry and Molecular Biology, OHSU
Postdoctoral fellow
* Combined expertise of biochemical, cellular, and molecular biology techniques were employed to study the role of a chromatin-associated protein (SSRP1) associated with an auto-immune disease called lupus (resulted in a first-author publication).
       - Demonstrated the role of SSRP1 in regulating homologous recombination and provided evidence   
         for a novel interaction between SSRP1 and another repair protein, Rad54.    
       - Provided mechanistic insights into the interaction of SSRP1 and Rad54 proteins. 
       - Generated (using site-directed mutagenesis) and characterized a DNA binding mutant of the    
          human SSRP1 gene.

* Managed an inter-institutional collaboration to increase the productivity of the laboratory and   
   deliver higher quality research.
Portland, Oregon Area
University of Sheffield, UK
Research Assistant
Cancer Genetics
PhD
University of Sheffield
https://www.linkedin.com/school/university-of-sheffield/
* Efficiently managed and completed several research projects focused on understanding the mode of action and the DNA repair mechanisms associated with a variety of chemotherapeutic agents (including hydroxyurea, thymidine, VP-16, camptothecin, and ionizing radiation).
        1. Provided evidence for a direct role of tumor suppressor p53 gene in protecting the stalled  
             replication forks (induced by chemotherapeutic drugs). This work was selected for a Scholar-in-    
             Training award at the AACR special meeting (2004, published as a first-author publication).
        2. Characterized thymidine-induced recombination substrate generated at the stalled replication        
             forks. 
	3. Studied the effects of over-expression of translesion synthesis polymerases, eta and iota, in   
             homologous recombination.
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Molecular Genetics
Masters
University of Leicester
https://www.linkedin.com/school/university-of-leicester/
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High and Senior School
Notre Dame Academy
American Association for Cancer Research
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Cheeky Scientist Association
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Women in Cancer Research
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An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity
DNA Repair
https://www.sciencedirect.com/science/article/abs/pii/S1568786418301484?via%3Dihub
BLM protein mitigates formaldehyde-induced genomic instability.
DNA Repair (Amst)
https://www.ncbi.nlm.nih.gov/pubmed/?term=anuradha+kumari+and+ohsu
Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway.
DNA Repair (Amst)
https://www.ncbi.nlm.nih.gov/pubmed/22186232
Modulation of UvrD helicase activity by covalent DNA-protein cross-links.
J Biol Chem.
https://www.ncbi.nlm.nih.gov/pubmed/20444702
A role for SSRP1 in recombination-mediated DNA damage response.
J Cell Biochem.
https://www.ncbi.nlm.nih.gov/pubmed/19639603
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV.
J Biol Chem.
https://www.ncbi.nlm.nih.gov/pubmed/18697749
p53 protects from replication-associated DNA double-strand breaks in mammalian cells.
Oncogene. 2004 Mar 25
https://www.ncbi.nlm.nih.gov/pubmed/14743204
Winner of the Innovate Children's Health Challenge
-
https://www.issuewire.com/the-innovate-childrens-health-challenge-names-winning-startups-1694955772591538
AACR Scholar-in-Training Award
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Introduction to Product Management (Udemy)
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PowerPoint Essential Training (Office 365/Microsoft 365) (LinkedIn Learning)
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https://www.linkedin.com/in/markaellisny
Mark Ellis
Senior VP, Medical and Scientific Strategy in Medical Communications
New York City Metropolitan Area
https://www.linkedin.com/in/rosemery-cook-phd
Rosemery Cook, PhD
Scientific Communications | Medical Affairs | Content Manager | Outdoor Enthusiast
Cambridge, MA
https://www.linkedin.com/in/leslie-moody-phd-cmpp-a3a7016
Leslie Moody, PhD, CMPP
Senior Scientific Director at Lumanity
Irving, TX
https://www.linkedin.com/in/tianyanxinsun
Tianyanxin (Tian) Sun, Ph.D.
Medical Writer, Scientist, Women's health/Oncology
Atlanta, GA
https://www.linkedin.com/in/jamieleemedcomm
Jamie Lee
Medical Communications Director at Exelixis
Dallas-Fort Worth Metroplex
https://ph.linkedin.com/in/cate-kang-55b722106
Cate Kang
None at None
Philippines
https://ca.linkedin.com/in/alexey-atrazhev-ab7b3144
Alexey Atrazhev
Senior Research Scientist at Aquila Diagnostics
Edmonton, AB
https://ca.linkedin.com/in/maryvonne-rosamont-ursulet
Maryvonne Rosamont-Ursulet
Research Scientist | Microbiology | Molecular & Cellular Biology | Assay Development | Pro-active Collaborator | Avid reader
Greater Vancouver Metropolitan Area
https://ca.linkedin.com/in/caishun-li-85468191
Caishun Li
Research Scientists at 48 Hour Discovery INC.
Edmonton, AB
https://ca.linkedin.com/in/lzarowny
Landon Zarowny
Scientist at 48Hour Discovery INC.
Edmonton, AB
https://ca.linkedin.com/in/ri-xu
Ri Xu, PhD
Freelancer | Medical Writer | Medical Communications | Patient Education | Medical Device | Clinical Evaluation Report
Montreal, QC
https://ca.linkedin.com/in/marinewalic
Marine Walic
Dynamic virologist ✶ Molecular biology scientist ✶ Avid learner ✶ Outdoors enthusiast ✶ Let's connect!
Vancouver, BC
https://ca.linkedin.com/in/christen-klinger
Christen Klinger, Ph.D.
Software Developer at DrugBank
Greater Edmonton Metropolitan Area
https://www.linkedin.com/in/raeesagupte
Raeesa Gupte, PhD
Medical Writer • Clinical Evaluation Reports • Medical Devices • Science Communication & Outreach • STEM Speaker • I help healthcare companies create clear, compelling content to engage and educate their target audience
Kansas City Metropolitan Area
https://www.linkedin.com/in/dory-larrabee-zayas
Dory Larrabee-Zayas
Writer, Editor, Consultant
New York, NY
https://www.linkedin.com/in/harry-wegley-96963515
Harry Wegley
Author
Renton, WA
https://www.linkedin.com/in/pauljboyle
Paul Boyle
Effective Technical Communications
Landers, CA
https://www.linkedin.com/in/shaunwaterman
Shaun Waterman
Award-winning reporter, editor and newsroom manager covering cybersecurity, space, homeland security, and technology/IT in the military and federal government.
Washington, DC
https://www.linkedin.com/in/arennekamp
Andrew Rennekamp, PhD
Medical Science Liaison at Seqirus
Boston, MA
https://www.linkedin.com/in/jrrockwell
Hasina J. Rockwell, CISSP, PMP
Senior Software Developer
Washington DC-Baltimore Area
Celebrating International Women's Month! Thank you, Lyn Wiesinger, for inspiring and supporting Michael S Shaw, MD, MBA!#thankyou #inspiringwomen…
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Anuradha Kumari
https://in.linkedin.com/in/anuradha-kumari-7698b84b
Senior Associate at PwC || Accenture|| IIBA Certified BA ECBA® || IIM Amritsar(MBA) || NIT Surat
Vadodara
Anuradha Kumari
https://in.linkedin.com/in/anuradha-kumari-4b66792b
Senior Software Engineer at Bank of America
Chennai
Anuradha kumari
https://in.linkedin.com/in/anuradha-kumari-325b93203
working as a intern
Noida
Anuradha Kumari
https://nl.linkedin.com/in/anuradha15
Frontend Consultant | MDE | GDE | MVP | A11Y Advocate | Speaker | MC | Content Creator
Amsterdam
Anuradha Kumari
https://in.linkedin.com/in/anuradha-kumari-0229654a
SAP Security and GRC Consultant Lead at Birlasoft
Pune