pinecone/core-2020-05-10-deduplication huggingface dataset:
MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma

MicroRNAs usually regulate gene expression negatively, and aberrant expression has been involved in the development of several types of cancers. Microarray profiling of microRNA expression was performed to define a microRNA signature in a series of mycosis fungoides tumor stage (MFt, n=21) and CD30+ primary cutaneous anaplastic large cell lymphoma (CD30+ cALCL, n=11) samples in comparison with inflammatory dermatoses (ID, n=5). Supervised clustering confirmed a distinctive microRNA profile for cutaneous T-cell lymphoma (CTCL) with respect to ID. A 40 microRNA signature was found in MFt including upregulated onco-microRNAs (miR-146a, miR-142-3p/5p, miR-21, miR-181a/b, and miR-155) and downregulated tumor-suppressor microRNAs (miR-200ab/429 cluster, miR-10b, miR-193b, miR-141/200c, and miR-23b/27b). Regarding CD30+ cALCL, 39 differentially expressed microRNAs were identified. Particularly, overexpression of miR-155, miR-21, or miR-142-3p/5p and downregulation of the miR-141/200c clusters were observed. DNA methylation in microRNA gene promoters, as expression regulatory mechanism for deregulated microRNAs, was analyzed using Infinium 450K array and approximately one-third of the differentially expressed microRNAs showed significant DNA methylation differences. Two different microRNA methylation signatures for MFt and CD30+ cALCL were found. Correlation analysis showed an inverse relationship for microRNA promoter methylation and microRNA expression. These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients
Forecasting errors, directional accuracy and profitability of currency trading: The case of EUR/USD exchange rate

We provide a comprehensive study of out-of-sample forecasts for the EUR/USD exchange rate based on multivariate macroeconomic models and forecast combinations. We use profit maximization measures based on directional accuracy and trading strategies in addition to standard loss minimization measures. When comparing predictive accuracy and profit measures, data snooping bias free tests are used. The results indicate that forecast combinations, in particular those based on principal components of forecasts, help to improve over benchmark trading strategies, although the excess return per unit of deviation is limited
Investigation of stimulated Brillouin scattering effects in radio-over-fiber distribution systems

Stimulated Brillouin scattering (SBS) imposes a limitation on the transmitted power in radio-over-fiber (RoF) distribution systems. By employing an optical filter at the transmitter that converts the optical microwave signal to single sideband format (in order to overcome dispersive fading), it is also possible to reduce the effect of SBS on system performance. In this paper the authors compare the cases of filtering the optical microwave signal at the transmitter or the remote site of a RoF system, in terms of the effect of SBS on system performance. The authors also investigate and demonstrate how the modulation depth of the optical-microwave data signal influences the Brillouin threshold in RoF distribution systems
High resolution photoemission study of SiOx/Si(111) interface disruption following in situ HfO₂deposition

We report on an in situ high resolution core level photoemission study of the early stages of interface formation between an ultrathin SiOx layer ( ∼ 0.3 nm) grown on the atomically clean Si(111) surface and a HfO2 dielectric layer. Si 2p core level spectra acquired at 130 eV photon energy reveal evidence of a chemically shifted component on the lower binding energy side of the substrate peak which is attributed to interface defect states resulting from the incorporation of silicon atoms from the substrate into the interfacial oxide at room temperature. This evidence of Si/SiOx interface disruption would be expected to increase charge carrier scattering mechanisms in the silicon and contribute to the generally observed mobility degradation in high-k stacks with ultrathin silicon oxide interface layers
Overview of VideoCLEF 2008: Automatic generation of\ud
topic-based feeds for dual language audio-visual content

The VideoCLEF track, introduced in 2008, aims to develop and evaluate tasks related to analysis of and access to multilingual multimedia content. In its first year, VideoCLEF piloted the Vid2RSS task, whose main subtask was the classification of dual language video (Dutchlanguage\ud
television content featuring English-speaking experts and studio guests). The task offered two additional discretionary subtasks: feed translation and automatic keyframe extraction. Task participants were supplied with Dutch archival metadata, Dutch speech transcripts,\ud
English speech transcripts and 10 thematic category labels, which they were required to assign to the test set videos. The videos were grouped by class label into topic-based RSS-feeds, displaying title, description and keyframe for each video. Five groups participated in the 2008 VideoCLEF track. Participants were required to collect their own training data; both Wikipedia and general web content were used. Groups deployed various classifiers (SVM, Naive Bayes and k-NN) or treated the problem as an information retrieval task. Both the Dutch speech transcripts and the archival metadata performed well as sources of indexing features, but no group succeeded in exploiting combinations of feature sources to significantly enhance performance. A small scale fluency/adequacy evaluation of the translation task output revealed the translation to be of sufficient quality to make it valuable to a non-Dutch speaking English speaker. For keyframe extraction, the strategy chosen was\ud
to select the keyframe from the shot with the most representative speech transcript content. The automatically selected shots were shown, with a small user study, to be competitive with manually selected shots. Future years of VideoCLEF will aim to expand the corpus and the class label list, as well as to extend the track to additional tasks
Decoherence induced spontaneous symmetry breaking

We study time dependence of exchange symmetry properties of Bell states when two-qubits interact with local baths having identical parameters. In case of classical noise, we consider a decoherence Hamiltonian which is invariant under swapping the first and second qubits. We find that as the system evolves in time, two of the three symmetric Bell states preserve their qubit exchange symmetry with unit probability, whereas the symmetry of the remaining state survives with a maximum probability of 0.5 at the asymptotic limit. Next, we examine the exchange symmetry properties of the same states under local, quantum mechanical noise which is modeled by two identical spin baths. Results turn out to be very similar to the classical case. We identify decoherence as the main mechanism leading to breaking of qubit exchange symmetry
X-ray diffraction line broadening under elastic deformation13; of a polycrystalline sample: An elastic-anisotropy effect

A homogeneous stress field imposed on a polycrystalline sample containing elastically anisotropic13; crystallites produces an inhomogeneous strain field. The average strain causes a shift of the13; diffraction-line position, and the variance of the strain is a measure of line broadening. Though the13; shift of the line is commonly observed, earlier attempts to measure the broadening caused by elastic13; anisotropy were not conclusive. In the article, expressions have been derived for the average strain13; and variance of strain for a polycrystalline sample cubic system! subjected to uniaxial elastic stress.13; The 310! and 222! lines of beta brass under an uniaxial load have been recorded using Co K aand13; Cu K aradiations, respectively. The average strain and variance of strain derived from the measured13; diffraction line profiles are in good agreement with those predicted by the theory. The present13; measurements provide conclusive evidence for the diffraction line broadening caused purely by13; elastic anisotropy. xA9; 2001 American Institute of Physics
Bicarbonato ingestion has no ergogenic effect on consecutive all out sprint test in MWX elite cyclists

The aim of the present study was to examine the effect of sodium bicarbonate ingestion on consecutive "all out" sprint tests, analyzing the acid-base status and its influence on performance and perceived effort. Ten elite bicycle motocross (BMX) riders (20.7 ± 1.4 years, training experience 8-12 years) participated in this study which consisted of two trials. Each trial consisted of three consecutive Wingate tests (WTs) separated by 15 min recovery. Ninety minutes prior to exercise subjects ingested either NaHCO(3) (-) (0.3 g kg(-1) body weight) or placebo. Blood samples were collected for the assessment of blood acid-base status: bicarbonate concentration ([HCO(3) (-)]), pH, base excess (BE) and blood lactate concentration ([La(-)]). Performance variables of peak power (PP), mean power (MP), time to peak power and fatigue index were calculated for each sprint. Significant differences (p < 0.05) were observed in acid-base variables [pH before WT1: 7.47 ± 0.05 vs. 7.41 ± 0.03; [HCO(3) (-)] before WT1: 29.08 ± 2.27 vs. 22.85 ± 0.24 mmol L(-1) (bicarbonate vs. placebo conditions, respectively)], but there were not significant differences in performance variables between trials [PP WT1: 1,610 ± 373 vs. 1,599 ± 370 W; PP WT2: 1,548 ± 460 vs. 1,570 ± 428 W; PP WT3: 1,463 ± 361 vs. 1,519 ± 364 W. MP WT1: 809 ± 113 vs. 812 ± 108 W; MP WT2: 799 ± 135 vs. 799 ± 124 W; MP WT3: 762 ± 165 vs. 782 ± 118 W (bicarbonate vs. placebo conditions, respectively)]. Rating of perceived effort (RPE) was not influenced nor ratings of perceived readiness. Sodium bicarbonate ingestion modified significantly the blood acid-base balance, although the induced alkalosis did not improve the Wingate test performance, RPE and perceived readiness across three consecutive WTs in elite BMX cyclists
On the specification and testing of inverters for stand-alone PV systems

Inverter features are reviewed from a PV systems perspective, with a view to contributing to possible codes, procurement specifications and testing procedures, in order to assure the technical quality of these systems. A laboratory testing campaign has been carried out on a representative set of sixteen currently available inverters and a set of the most common AC appliances. The results of the tests are discussed with the aim of divulging the particular features of operating AC appliances in PV systems and the provisions to be taken into account in PV system design. The development of testing procedures has followed the motto ?keep it as simple as possible?, in order to make their application easier in conventional laboratories in developing countries
Simulation of the stretch blow moulding process: from the modelling of the microstructure evolution to the end-use elastic properties of polyethylene terephthalate bottles

The original publication is available at www.springerlink.comThe whole stretch blow-moulding process of PET bottles is simulated at the usual process temperature in order to predict the elastic end-use properties of the bottles. An anisotropic viscoplastic constitutive law, coupled with microscopic variables, is dentified from uniaxial tensile tests performed at different strain rates and temperatures. The microstructure evolution is characterised by crystallinity measurements from interrupted
tests and frozen samples. For each specimen tested, the Young modulus is measured at room temperature. Numerical simulations of the blow moulding process are run using the C-NEM method. A micromechanical modelling is post-processed after the simulation to predict the elastic properties. Predictions of Young modulus distributions in bottles are in agreement with the ones measured on blow-moulded bottles
Evaluation of residual stress relaxation and its effect on fatigue strength of AISI 316L stainless steel ground surfaces: Experimental and numerical approaches

This paper is aimed at evaluating the residual stress relaxation and its effect on the fatigue strength of AISI 316L steel ground surfaces in comparison to electro-polished surfaces. An experimental evaluation was performed using 3-point and 4-point bending fatigue tests at Rr = 0.1 on two sets of notched spec-imens ﬁnished by electro-polishing and grinding. The residual stress ﬁelds were measured at the notch root of specimens, before and after fatigue tests, by means of the X-ray diffraction technique. It was found a degradation of about 35% for the 4-point bending fatigue limit at 2  106 cycles of the ground spec-imens in comparison to the electro-polished ones. This degradation is associated with a slight relaxation of the grinding residual stresses which remain signiﬁcant tensile stresses at the stabilized state. While under the 3-point bending test, these residual stresses relax completely and provoke a noticeable increase of the fatigue limit estimated at about 50% in comparison to the 4-point bending fatigue test. The numerical evaluation of residual stress relaxation was carried out by FE analyses of the cyclic hard-ening behaviour of the ground layer. The isotropic and nonlinear kinematic model proposed by Chaboche was used and calibrated for the base material and the ground layer. The results show that residual stres-ses relax to a stabilized state characterized by elastic-shakedown response. This stabilization is occurred after the ﬁrst cycle of the 4-point bending test corresponding to the higher stress concentration (Kt- 4p = 1.66), while it requires many cycles under the 3-point bending test corresponding to the lower stress concentration (Kt-3p = 1.54). The incorporation of stabilized residual stress values into the Dang Van’s cri-terion has permitted to predict with an acceptable accuracy the fatigue limits under both bending modes
Comprehension of chip formation in laser assisted machining

Laser Assisted Machining (LAM) improves the machinability of materials by locally heating the workpiece just prior to cutting. Experimental investigations have confirmed that the cutting force can be decreased, by as much as 40%, for various materials. In order to understand the effect of the laser on chip formation and on the temperature fields in the different deformation zones, thermo-mechanical simulations were undertaken. A thermo-mechanical model for chip formation was also undertaken. Experimental tests for the orthogonal cutting of 42CrMo4 steel were used to validate the simulation. The temperature fields allow us to explain the reduction in the cutting force and the resulting residual stress fields in the workpiece.Contrat Plan Etat Région (CPER) Pays de la Loir
Spin correlation and relaxational dynamics in molecular-based single-chain magnets

We report the combined measurements of the dc susceptibility 0, the ac susceptibility , and the NMR relaxation rate T for the molecular-based heterometallic single-chain magnet [Mn(saltmen)]2[Ni(pao)2(py)2](PF6)2. At low temperatures, this system is well described by a one-dimensional array of effective spin S=3 chains comprising the MnIII-NiII-MnIII trimers and treated as the S=3 Ising chain with the single-ion term (Blume-Capel model). Using the exact solution of the model and based on the picture that the random motion of the local domain walls dominates the low-temperature spin dynamics, we succeeded in reproducing the experimental results of the dc susceptibility 0, the ac susceptibility , and the 19F-NMR relaxation rate T in a consistent manner
Efficient production of bisphenol-A by utilizing cation-exchange polystyrene resins that are cross-linked by naphthalene or a biphenyl unit

Ion-exchange materials are well known for their utilization in the processes of water treatment,1, 2, 3, 4, 5 demineralization,6, 7 water softening,8, 9, 10 ultra purification of water11, 12 and removal of unwanted ions,13, 14 as well as in chemical processing.15 One ion-exchange material is acidic sulfonated polystyrene-divinylbenzene (DVB) cation-exchange resin, which has an important role in the production of bisphenol-A by participating in an acid-catalyzed condensation reaction between phenol and acetone. Bisphenol-A is a very important raw material for the synthesis of epoxy resins and polycarbonates; thus, >400 000 tons of bisphenol-A have recently been domestically produced
Acquiring and sharing tacit knowledge in software development teams: An empirical study

Context: Sharing expert knowledge is a key process in developing software products. Since expert knowledge is mostly tacit, the acquisition and sharing of tacit knowledge along with the development of a transactive memory system (TMS) are significant factors in effective software teams.\ud
Objective: We seek to enhance our understanding human factors in the software development process and provide support for the agile approach, particularly in its advocacy of social interaction, by answering two questions: How do software development teams acquire and share tacit knowledge? What roles do tacit knowledge and transactive memory play in successful team performance? Method: A theoretical model describing the process for acquiring and sharing tacit knowledge and development of a TMS through social interaction is presented and a second predictive model addresses the two research questions above. The elements of the predictive model and other demographic variables were incorporated into a larger online survey for software development teams, completed by 46 software SMEs, consisting of 181 individual team members.\ud
Results: Our results show that team tacit knowledge is acquired and shared directly through good quality social interactions and through the development of a TMS with quality of social interaction playing a greater role than transactive memory. Both TMS and team tacit knowledge predict effectiveness but not efficiency in software teams.\ud
Conclusion: It is concluded that TMS and team tacit knowledge can differentiate between low- and high-performing teams in terms of effectiveness, where more effective teams have a competitive advantage in developing new products and bringing them to market. As face-to-face social interaction is key, collocated, functionally rich, domain expert teams are advocated rather than distributed teams, though arguably the team manager may be in a separate geographic location provided that there is frequent communication and effective use of issue tracking tools as in agile teams
A Memetic Paradigm of Project Management

This paper aims to fuel the discussion on examining project management research from different perspectives. A new memetic approach to project management is presented that promotes a new way to examine the discipline of project management. Project management is claimed to be a memeplex with the language and stories of its scholars and practitioners at its core; shaping and restricting human behaviour, and creating impoverished mental models of project management. The paper suggests that a new memetic approach to project management will help lift restrictions imposed by the traditional research approach, and enrich our mental maps of project management to serve us better
Fission of hyper-hyperdeformed $^{56}$Ni: a clustering analysis with in mean-field approaches

The structure of 56Ni is sudied by using the non-relativistic Skyrme Hartree-Fock and the relativistic Hartree approximation in an axially deformed cylindrical coordinate. We found several intrinsic excited states, including the spherical ground-state solution. Without including any extra $\alpha$-cluster correlations, the possible cluster configurations of the resonance states are analyzed, showing the multipleN=Z, $\alpha$-nucleus like, cluster structures for hyper-deformed states, but, contrary to the recent experimental possibility of a ternary fission decay, we predict a two cluster or symmetric fission configuration for the hyper-hyperdeformed stat
Egalitarian Paradise or Factory Drudgery? Organizing Knowledge Production in High Energy Physics (HEP) Laboratories

The organization of cutting-edge HEP laboratories has evolved in the intersection of academia, state agencies, and industry. Exponentially ever-larger and more complex knowledge-intensive operations, the laboratories have often faced the challenges of, and required organizational solutions similar to, those identified by a cluster of diverse theories falling under the larger heading of organization theory. The cluster has either shaped or accounted for the organization of industry and state administration. The theories also apply to HEP laboratories, as they have gradually and uniquely hybridized their principles and solutions. Yet scholarship has virtually ignored this linkage and has almost exclusively focused on the laboratories’ presumably unique egalitarian organizational aspects. Guided by the principles developed in the organization theory cluster, we identify the basic organizational features of HEP laboratories in relation to their pursuit of narrow and broad epistemic goals. We also provide a set of criteria and methods for assessing the efficiency of the identified organizational features in achieving such goals
Influence of the exchange-correlation functional on the quasi-harmonic lattice dynamics of II-VI semiconductors

We perform a systematic comparison of the finite-temperature structure and properties of four bulk semiconductors (PbS, PbTe, ZnS, and ZnTe) predicted by eight popular exchange-correlation functionals from quasi-harmonic lattice-dynamics calculations. The performance of the functionals in reproducing the temperature dependence of a number of material properties, including lattice parameters, thermal-expansion coefficients, bulk moduli, heat capacities, and phonon frequencies, is evaluated quantitatively against available experimental data. We find that the phenomenological over-and under-binding characteristics of the local-density approximation and the PW91 and Perdew-Burke-Enzerhof (PBE) generalised-gradient approximation (GGA) functionals, respectively, are exaggerated at finite temperature, whereas the PBEsol GGA shows good general performance across all four systems. The Tao-Perdew-Staroverov-Scuseria (TPSS) and revTPSS meta-GGAs provide relatively small improvements over PBE, with the latter being better suited to calculating structural and dynamical properties, but both are considerably more computationally demanding than the simpler GGAs. The dispersion-corrected PBE-D2 and PBE-D3 functionals perform well in describing the lattice dynamics of the zinc chalcogenides, whereas the lead chalcogenides appear to be challenging for these functionals. These findings show that quasi-harmonic calculations with a suitable functional can predict finite-temperature structure and properties with useful accuracy, and that this technique can serve as a means of evaluating the performance of new functionals in the future
Deployment of titanium thermal barrier for low-temperature carbon nanotube growth

Chemical vapor-synthesized carbon nanotubes are typically grown at temperatures around 600 °C. We report on the deployment of a titanium layer to help elevate the constraints on the substrate temperature during plasma-assisted growth. The growth is possible through the lowering of the hydrocarbon content used in the deposition, with the only source of heat provided by the plasma. The nanotubes synthesized have a small diameter distribution, which deviates from the usual trend that the diameter is determined by the thickness of the catalyst film. Simple thermodynamic simulations also show that the quantity of heat, that can be distributed, is determined by the thickness of the titanium layer. Despite the lower synthesis temperature, it is shown that this technique allows for high growth rates as well as better quality nanotubes. © 2005 American Institute of Physics