pinecone/core-2020-05-10-deduplication huggingface dataset:
An improved multiple model particle ﬁltering approach for manoeuvring target tracking using Airborne GMTI with geographic information

This paper proposes a novel ground vehicle tracking method using an airborne ground moving target\ud
indicator radar where the surrounding geographic information is considered to determine vehicle’s\ud
movement type as well as constrain its positions. Multiple state models corresponding to diﬀerent\ud
movement modes are applied to represent the vehicle’s behaviour within diﬀerent terrain conditions.\ud
Based on geographic conditions and multiple state models, a constrained variable structure multiple\ud
model particle ﬁlter algorithm aided by particle swarm optimisation is proposed. Compared with\ud
the traditional multiple model particle ﬁltering schemes, the proposed algorithm utilises a particle\ud
swarm optimisation technique for the particle ﬁlter which generates more eﬀective particles and\ud
generated particles are constrained into the feasible geographic region. Numerical simulation results\ud
in a realistic environment show that the proposed method achieves better tracking performance\ud
compared with current state-of-the-art ones for manoeuvring vehicle tracking
Questions about answers : probing teachers’ awareness and planned remediation of learners’ misconceptions about electric circuits

This article reports an exploratory multi-case study on how science teachers understand and envisage
addressing learners’ misconceptions about electric circuits. Four teachers from schools in and around a
large South African city participated in the study. An open-ended questionnaire was designed in a novel
way, questioning teachers about wrong answers they expected from their learners in test items suitable
for Grade 9. Semi-structured interviews supported the questionnaire results, providing insight into the
teachers’ understanding of learners’ misconceptions, and their ideas about how learners’ misconceptions
should be addressed. Two of the teachers showed insight into learners’ conceptual difficulties, reflecting
on learners’ thinking. Another teacher indicated some typical wrong answers but seldom understood the
misconceptions leading to these mistakes, while the remaining teacher did not expect typical wrong
answers corresponding to well-known misconceptions. All the teachers indicated that they would address
learners’ mistakes mostly by practical work or demonstrations, but only two of the teachers also referred
to the importance of developing conceptual understanding. Results suggest that these teachers’
understanding of learners’ misconceptions relates to their own subject matter knowledge. Furthermore,
the study showed that the technique of questioning teachers about anticipated learners’ answers is a
promising way of probing teachers’ understanding of learners’ misconceptions and the strategies they
envisage using to address these misconceptions. It is recommended that learners’ misconceptions be
addressed explicitly in teacher preparation and professional development programmes as an avenue to
develop teachers’ pedagogical content knowledge (PCK).http://www.journals.co.za/ej/ejour_saarmste.htmltm201
Nuclear translocation of the phosphoprotein Hop (Hsp70/Hsp90 organizing protein) occurs under heat shock, and its proposed nuclear localization signal is involved in Hsp90 binding

AbstractThe Hsp70–Hsp90 complex is implicated in the folding and regulation of numerous signaling proteins, and Hop, the Hsp70–Hsp90 Organizing Protein, facilitates the association of this multichaperone machinery. Phosphatase treatment of mouse cell extracts reduced the number of Hop isoforms compared to untreated extracts, providing the first direct evidence that Hop was phosphorylated in vivo. Furthermore, surface plasmon resonance (SPR) spectroscopy showed that a cdc2 kinase phosphorylation mimic of Hop had reduced affinity for Hsp90 binding. Hop was predominantly cytoplasmic, but translocated to the nucleus in response to heat shock. A putative bipartite nuclear localization signal (NLS) has been identified within the Hsp90-binding domain of Hop. Although substitution of residues within the major arm of this proposed NLS abolished Hop–Hsp90 interaction as determined by SPR, this was not sufficient to prevent the nuclear accumulation of Hop under leptomycin-B treatment and heat shock conditions. These results showed for the first time that the subcellular localization of Hop was stress regulated and that the major arm of the putative NLS was not directly important for nuclear translocation but was critical for Hop–Hsp90 association in vitro. We propose a model in which the association of Hop with Hsp90 and the phosphorylated status of Hop both play a role in the mechanism of nucleo-cytoplasmic shuttling of Hop
Maximum H-colourable subdigraphs and constraint optimization with arbitrary weights

AbstractIn the maximum constraint satisfaction problem (Max CSP), one is given a finite collection of positive-weight constraints on overlapping sets of variables, and the goal is to assign values from a given domain to the variables so that the total weight of satisfied constraints is maximized. We consider this problem and its variant Max AW CSP where the weights are allowed to be both positive and negative, and study how the complexity of the problems depends on the allowed constraint types. We prove that Max AW CSP over an arbitrary finite domain exhibits a dichotomy: it is either polynomial-time solvable or NP-hard. Our proof builds on two results that may be of independent interest: one is that the problem of finding a maximum H-colourable subdigraph in a given digraph is either NP-hard or trivial depending on H, and the other a dichotomy result for Max CSP with a single allowed constraint type
2016 Expert consensus document on prevention, diagnosis and treatment of short-term peripheral venous catheter-related infections in adults

AbstractThe use of endovascular catheters is a routine practice in secondary and tertiary care level hospitals. The short-term use of peripheral catheters has been found to be associated with the risk of nosocomial bacteraemia, resulting in morbidity and mortality. Staphylococcus aureus is mostly associated with peripheral catheter insertion. This Consensus Document has been prepared by a panel of experts of the Spanish Society of Cardiovascular Infections, in cooperation with experts from the Spanish Society of Internal Medicine, Spanish Society of Chemotherapy, and the Spanish Society of Thoracic-Cardiovascular Surgery, and aims to define and establish guidelines for the management of short duration peripheral vascular catheters. The document addresses the indications for insertion, catheter maintenance, registering, diagnosis and treatment of infection, indications for removal, as well as placing an emphasis on continuous education as a drive toward quality. Implementation of these guidelines will allow uniformity in use, thus minimizing the risk of infections and their complications
Lifetime measurements of the first 2+ states in 104,106Zr: Evolution of ground-state deformations

AbstractThe first fast-timing measurements from nuclides produced via the in-flight fission mechanism are reported. The lifetimes of the first 2+ states in 104,106Zr nuclei have been measured via β-delayed γ-ray timing of stopped radioactive isotope beams. An improved precision for the lifetime of the 21+ state in 104Zr was obtained, τ(21+)=2.90−20+25 ns, as well as a first measurement of the 21+ state in 106Zr, τ(21+)=2.60−15+20 ns, with corresponding reduced transition probabilities of B(E2;21+→0g.s.+)=0.39(2) e2b2 and 0.31(1) e2b2, respectively. Comparisons of the extracted ground-state deformations, β2=0.39(1) (104Zr) and β2=0.36(1) (106Zr) with model calculations indicate a persistence of prolate deformation. The data show that 104Zr is the most deformed of the neutron-rich Zr isotopes measured so far
Mapping household direct energy consumption in the United Kingdom to provide a new perspective on energy justice

AbstractTargets for reductions in carbon emissions and energy use are often framed solely in terms of percentage reductions. However, the amount of energy used by households varies greatly, with some using considerably more than others and, therefore, potentially being able to make a bigger contribution towards overall reductions. Using two recently released UK datasets based on combined readings from over 70 million domestic energy meters and vehicle odometers, we present exploratory analyses of patterns of direct household energy usage.Whilst much energy justice work has previously focussed on energy vulnerability, mainly in low consumers, our findings suggest that a minority of areas appear to be placing much greater strain on energy networks and environmental systems than they need. Households in these areas are not only the most likely to be able to afford energy efficiency measures to reduce their impacts, but are also found to have other capabilities that would allow them to take action to reduce consumption (such as higher levels of income, education and particular configurations of housing type and tenure). We argue that these areas should therefore be a higher priority in the targeting of policy interventions
Saddle point inflation from f(R) theory

AbstractWe analyse several saddle point inflationary scenarios based on power-law f(R) models. We investigate inflation resulting from f(R)=R+αnM2(1−n)Rn+αn+1M−2nRn+1 and f(R)=∑nlαnM2(1−n)Rn as well as l→∞ limit of the latter. In all cases we have found relation between αn coefficients and checked consistency with the PLANCK data as well as constraints coming from the stability of the models in question. Each of the models provides solutions which are both stable and consistent with PLANCK data, however only in parts of the parameter space where inflation starts on the plateau of the potential, some distance from the saddle. And thus all the correct solutions bear some resemblance to the Starobinsky model
On the choice of stabilizing sub-grid for convection–diffusion problem on rectangular grids

AbstractA stabilizing sub-grid which consists of a single additional node in each rectangular element is analyzed for solving the convection–diffusion problem, especially in the case of small diffusion. We provide a simple recipe for spotting the location of the additional node that contributes a very good stabilizing effect to the overall numerical method. We further study convergence properties of the method under consideration and prove that the standard Galerkin finite element solution on augmented grid produces a discrete solution that satisfies the same type of a priori error estimates that are typically obtained with the SUPG method. Some numerical experiments that confirm the theoretical findings are also presented
Coherent ψ(2S) photo-production in ultra-peripheral PbPb collisions at sNN=2.76 TeV

AbstractWe have performed the first measurement of the coherent ψ(2S) photo-production cross section in ultra-peripheral PbPb collisions at the LHC. This charmonium excited state is reconstructed via the ψ(2S)→l+l− and ψ(2S)→J/ψπ+π− decays, where the J/ψ decays into two leptons. The analysis is based on an event sample corresponding to an integrated luminosity of about 22 μb−1. The cross section for coherent ψ(2S) production in the rapidity interval −0.9<y<0.9 is dσψ(2S)coh/dy=0.83±0.19(stat+syst) mb. The ψ(2S) to J/ψ coherent cross section ratio is 0.34−0.07+0.08(stat+syst). The obtained results are compared to predictions from theoretical models
Evolution of the upper and lower landing site after endovascular aortic aneurysm repair

BackgroundThe evolution and correlation between the aortic neck and distally located iliac necks after endovascular treatment of abdominal aortic aneurysms (AAAs) was studied.MethodsOf 179 patients who had undergone AAA repair between 2003 and 2007, 61 received the same radiologic follow-up and were included in this retrospective study. Data for 61 aortic necks and 115 iliac arteries were analyzed using the preoperative scan, 1-month visit, and final follow-up, with a minimum mean follow-up of 24 ± 15.2 months. Three measurements were taken of the aortic neck: subrenal (D1a), 15 mm below the lowest renal artery (D1b), and at the origin of the aneurysm (D1c). Three measurements were taken at the level of the iliac arteries: origin (Da), middle (Db), and the iliac bifurcation (Dc). These measurements were analyzed using analysis of variance and Spearman correlation coefficient. The results were evaluated for subsequent endoleaks, migrations, and reinterventions. All diameters were compared between patients with a regression of >10% in the greatest diameter of AAA at last follow-up (group A, n = 35) and those without (group B, n = 26).ResultsAll diameters (in mm) increased significantly over time at the level of the proximal neck (D1a = 3.7 ± 2.8, P = .018; D1b = 4.4 ± 2.5, P = .016; D1c = 4.3 ± 3.1, P = .036) and iliac arteries (Da = 2.1 ± 0.2, P = .0006; Db = 2.5 ± 0.5, P = .0006; Dc = 3 ± 0.7, P = .007). The increase in diameters at the proximal neck and iliac arteries evolved independently (insignificant correlation), with the exception of D1b and Dc (P = .006), which showed a weak correlation (r = 0.363). The group A patients presented increases in all diameters, although to a less significant extent (P < .05) than group B patients. During follow-up, a proximal endoleak and a distal endoleak occurred, both requiring reintervention.ConclusionsOur results show a trend toward dilatation of the aortic neck and iliac arteries, with no correlation between the two levels, even in patients with a regression of the aneurysm sac during follow-up. Although this study found no correlation with the occurrence of endoleaks, our results suggest the need for a longer follow-up, especially on the landing sites
The detection of wind turbine shaft misalignment using temperature monitoring

AbstractTemperature is a parameter increasingly monitored in wind turbine systems. This paper details a potential temperature monitoring technique for use on shaft couplings. Such condition monitoring methods aid fault detection in other areas of wind turbines. However, application to shaft couplings has not previously been widely researched.A novel temperature measurement technique is outlined, using an infra-red thermometer which can be applied to online condition monitoring. The method was validated and investigated through real time shaft alignment tests. Different modes of misalignment including offset and angular were investigated. This allowed analysis of the relationship between a change in shaft alignment and a change in temperature. The rate of change was found to be a factor of condition through exploring changes in ambient and operating temperatures. The test rig allowed quantification on a small scale and potential causes and effects of temperature changes are discussed
Psychometric properties of reaction time based experimental paradigms measuring anxiety-related information-processing biases in children

AbstractTheoretical frameworks highlight the importance of threat-related information-processing biases for understanding the emergence of anxiety in childhood. The psychometric properties of several tasks measuring these biases and their associations with anxiety were examined in an unselected sample of 9-year-old children (N=155). In each task, threat bias was assessed using bias scores reflecting task performance on threat versus non-threat conditions. Reliability was assessed using split–half and test–retest correlations of mean reaction times (RTs), accuracy and bias indices. Convergence between measures was also examined. Mean RTs showed substantial split–half and test–retest correlations. Bias score reliability coefficients were near zero and non-significant, suggesting poor reliability in children of this age. Additionally, associations between bias scores and anxiety were weak and inconsistent and performance between tasks showed little convergence. Bias scores from RT based paradigms in the current study lacked adequate psychometric properties for measuring individual differences in anxiety-related information-processing in children
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

SummaryBackgroundOsteoarthritis is the most common form of arthritis worldwide and is a major cause of pain and disability in elderly people. The health economic burden of osteoarthritis is increasing commensurate with obesity prevalence and longevity. Osteoarthritis has a strong genetic component but the success of previous genetic studies has been restricted due to insufficient sample sizes and phenotype heterogeneity.MethodsWe undertook a large genome-wide association study (GWAS) in 7410 unrelated and retrospectively and prospectively selected patients with severe osteoarthritis in the arcOGEN study, 80% of whom had undergone total joint replacement, and 11 009 unrelated controls from the UK. We replicated the most promising signals in an independent set of up to 7473 cases and 42 938 controls, from studies in Iceland, Estonia, the Netherlands, and the UK. All patients and controls were of European descent.FindingsWe identified five genome-wide significant loci (binomial test p≤5·0×10−8) for association with osteoarthritis and three loci just below this threshold. The strongest association was on chromosome 3 with rs6976 (odds ratio 1·12 [95% CI 1·08–1·16]; p=7·24×10−11), which is in perfect linkage disequilibrium with rs11177. This SNP encodes a missense polymorphism within the nucleostemin-encoding gene GNL3. Levels of nucleostemin were raised in chondrocytes from patients with osteoarthritis in functional studies. Other significant loci were on chromosome 9 close to ASTN2, chromosome 6 between FILIP1 and SENP6, chromosome 12 close to KLHDC5 and PTHLH, and in another region of chromosome 12 close to CHST11. One of the signals close to genome-wide significance was within the FTO gene, which is involved in regulation of bodyweight—a strong risk factor for osteoarthritis. All risk variants were common in frequency and exerted small effects.InterpretationOur findings provide insight into the genetics of arthritis and identify new pathways that might be amenable to future therapeutic intervention.FundingarcOGEN was funded by a special purpose grant from Arthritis Research UK
Searches for a heavy scalar boson H decaying to a pair of 125 GeV Higgs bosons hh or for a heavy pseudoscalar boson A decaying to Zh, in the final states with h→ττ

AbstractA search for a heavy scalar boson H decaying into a pair of lighter standard-model-like 125 GeV Higgs bosons hh and a search for a heavy pseudoscalar boson A decaying into a Z and an h boson are presented. The searches are performed on a data set corresponding to an integrated luminosity of 19.7 fb−1 of pp collision data at a centre-of-mass energy of 8 TeV, collected by CMS in 2012. A final state consisting of two τ leptons and two b jets is used to search for the H→hh decay. A final state consisting of two τ leptons from the h boson decay, and two additional leptons from the Z boson decay, is used to search for the decay A→Zh. The results are interpreted in the context of two-Higgs-doublet models. No excess is found above the standard model expectation and upper limits are set on the heavy boson production cross sections in the mass ranges 260<mH<350 GeV and 220<mA<350 GeV
Immune oxysterols: Role in mycobacterial infection and inflammation

AbstractInfection remains an important cause of morbidity and mortality. Natural defenses to infection are mediated by intrinsic/innate and adaptive immune responses. While our understanding is considerable it is incomplete and emerging areas of research such as those related to the immune-metabolic axis are only beginning to be appreciated. There is increasing evidence showing a connection between immune signalling and the regulation of sterol and fatty acid metabolism. In particular, metabolic intermediates of cholesterol biosynthesis and its oxidized metabolites (oxysterols) have been shown to regulate adaptive immunity and inflammation and for innate immune signalling to regulate the dynamics of cholesterol synthesis and homeostasis. The side-chain oxidized oxysterols, 25-hydroxycholesterol (25HC) and vitamin D metabolites (vitamin D3 and vitamin D2), are now known to impart physiologically profound effects on immune responses. Macrophages play a frontline role in this process connecting immunity, infection and lipid biology, and collaterally are a central target for infection by a wide range of pathogens including viruses and bacteria, especially intracellular bacteria such as mycobacteria. Clinical manifestations of disease severity in the infected host are likely to pay tribute to perturbations of the metabolic-immune phenomena found in lymphocytes and myeloid cells. Historically and consistent with this notion, vitamin D based oxysterols have had a long association with promoting clinical improvements to patients infected with Mycobacterium tuberculosis. Hence understanding the role of early metabolic mediators of inflammatory responses to infection in particular oxysterols, will aid in the development of urgently needed host directed therapeutic and diagnostic design innovation to combat adverse infection outcomes and antibiotic resistance
Stray-field NMR diffusion q-space diffraction imaging of monodisperse coarsening foams

AbstractThe technique of stray field diffusion NMR is adapted to study the diffusion properties of water in monodisperse wet foams. We show for the first time, that the technique is capable of observing q-space diffusion diffraction peaks in monodisperse aqueous foams with initial bubble sizes in the range of 50–85μm. The position of the peak maximum can be correlated simply to the bubble size in the foam leading to a technique that can investigate the stability of the foam over time.The diffusion technique, together with supplementary spin-spin relaxation analysis of the diffusion data is used to follow the stability and coarsening behaviour of monodisperse foams with a water fraction range between 0.24 and 0.33. The monodisperse foams remain stable for a period of hours in terms of the initial bubble size. The duration of this stable period correlates to the initial size of the bubbles. Eventually the bubbles begin to coarsen and this is observed in changes in the position of the diffusion diffraction maxima
“Hot entanglement”? – A nonequilibrium quantum field theory scrutiny

AbstractThe possibility of maintaining entanglement in a quantum system at finite, even high, temperatures – the so-called ‘hot entanglement’ – has obvious practical interest, but also requires closer theoretical scrutiny. Since quantum entanglement in a system evolves in time and is continuously subjected to environmental degradation, a nonequilibrium description by way of open quantum systems is called for. To identify the key issues and the contributing factors that may permit ‘hot entanglement’ to exist, or the lack thereof, we carry out a model study of two spatially-separated, coupled oscillators in a shared bath depicted by a finite-temperature scalar field. From the Langevin equations we derived for the normal modes and the entanglement measure constructed from the covariance matrix we examine the interplay between direct coupling, field-induced interaction and finite separation on the structure of late-time entanglement. We show that the coupling between oscillators plays a crucial role in sustaining entanglement at intermediate temperatures and over finite separations. In contrast, the field-induced interaction between the oscillators which is a non-Markovian effect becomes very ineffective at high temperature. We determine the critical temperature above which entanglement disappears to be bounded in the leading order by the inverse frequency of the center-of-mass mode of the reduced oscillator system, a result not unexpected, which rules out hot entanglement in such settings