pinecone/core-2020-05-10-deduplication huggingface dataset:
Search for the production of an excited bottom quark decaying to tW in proton-proton collisions at √s = 8 TeV

A search is presented for a singly produced excited bottom quark (b*) decaying to a top quark and a W boson in the all-hadronic, lepton+jets, and dilepton final states in proton-proton collisions at s=8(Formula Presented.)TeV recorded by the CMS experiment at the CERN LHC. Data corresponding to an integrated luminosity of 19.7 fb−1 are used. No significant excess of events is observed with respect to standard model expectations. We set limits at 95% confidence on the product of the b* quark production cross section and its branching fraction to tW. The cross section limits are interpreted for scenarios including left-handed, right-handed, and vector-like couplings of the b* quark and are presented in the two-dimensional coupling plane based on the production and decay coupling constants. The masses of the left-handed, right-handed, and vector-like b* quark states are excluded at 95% confidence below 1390, 1430, and 1530 GeV, respectively, for benchmark couplings. This analysis gives the most stringent limits on the mass of the b∗ quark to date.[Figure not available: see fulltext.] © 2016, The Author(s).The Scientific and Technical Research Council of Turkey, and Turkish Atomic Energy Authorit
Search for supersymmetry in electroweak production with photons and large missing transverse energy in pp collisions at √s=8TeV

Results are reported from a search for supersymmetry with gauge-mediated supersymmetry breaking in electroweak production. Final states with photons and large missing transverse energy ( ETmiss) were examined. The data sample was collected in pp collisions at √s=8TeV with the CMS detector at the LHC and corresponds to 7.4fb-1. The analysis focuses on scenarios in which the lightest neutralino has bino- or wino-like components, resulting in decays to photons and gravitinos, where the gravitinos escape undetected. The data were obtained using a specially designed trigger with dedicated low thresholds, providing good sensitivity to signatures with photons, ETmiss, and low hadronic energy. No excess of events over the standard model expectation is observed. The results are interpreted using the model of general gauge mediation. With the wino mass fixed at 10GeV above that of the bino, wino masses below 710GeV are excluded at 95% confidence level. Constraints are also set in the context of two simplified models, for which the analysis sets the lowest cross section limits on the electroweak production of supersymmetric particles.The Scientific and Technical Research Council of Turkey, and Turkish Atomic Energy Authorit
Economic Crises, Maternal and Infant Mortality, Low Birth Weight and Enrollment Rates: Evidence from Argentina’s Downturns

This study investigates the impact of recent crises in Argentina (including the severe downturn of 2001–02) on health and education outcomes. The identification strategy relies on both the inter-temporal and the cross-provincial co-variation between changes in regional GDP and outcomes by province. These results indicate significant and substantial effects of aggregate fluctuations on maternal and infant mortality and low birth weight, with countercyclical though not significant patterns for enrollment rates. Finally, provincial public expenditures on health and education are correlated with the incidence of low birth weight and school enrollment for teenagers, with worsening results associated with GDP declines.
Intersecting P-free families

We study the problem of determining the size of the largest intersecting P-free family for a given partially ordered set (poset) P. In particular, we find the exact size of the largest intersecting B-free family where B is the butterfly poset and classify the cases of equality. The proof uses a new generalization of the partition method of Griggs, Li and Lu. We also prove generalizations of two well-known inequalities of Bollobás and Greene, Katona and Kleitman in this case. Furthermore, we obtain a general bound on the size of the largest intersecting P-free family, which is sharp for an infinite class of posets originally considered by Burcsi and Nagy, when n is odd. Finally, we give a new proof of the bound on the maximum size of an intersecting k-Sperner family and determine the cases of equality. © 2017 Elsevier Inc
Igneous sills record far-field and near-field stress interactions during volcano construction : Isle of Mull, Scotland

Acknowledgments This work was undertaken during T.L. Stephens's PhD studentship, supported by the Central England Natural Environment Research Council (NERC) Training Alliance (CENTA) [award reference: 1503848]. The authors would like to thank Simon Martin for useful fieldwork discussions; Eline Goudier and Meline Massot for assistance with sample density measurements; and Natalie Farrell for advice and constructive comments on earlier drafts of the manuscript. The authors would also like to thank Michael Bickle, Craig Magee and an anonymous reviewer for constructive comments during review. Supplementary material related to this article can be found online at http://dx.doi.org/10.1016/j.epsl.2017.09.003.Peer reviewedPublisher PD
Social Work with Marginalised People Who have a Mild or Borderline Intellectual Disability: Practicing Gentleness and Encouraging Hope

People with mild or borderline intellectual disabilities are a group of people who usually do not meet the eligibility criteria for specialist disability services, yet are high users of many generalist services, such as mental health, child protection, and criminal justice systems. They may traverse many services, often entering, exiting, and returning to the same service providers with few positive results. This article explores the practice approach of the Meryton Association, a medium-sized nongovernment agency located in Brisbane, Australia. The Meryton Association provides social work support to people with mild to borderline intellectual disabilities, actively assisting this group to build relationships, resources, knowledge, and autonomy in their everyday lives. Using qualitative in-depth interviews with Meryton Association staff and secondary analysis of Meryton Association policy and practice documents, the challenges and opportunities of using this practice approach have been documented. The article proposes that specialist services are needed that use a developmental approach, stress the importance of relationship, and the need to practice gentleness and hope in social worker-client interaction.Griffith Health, School of Human Services and Social WorkFull Tex
The ’WHO Safe Communities’ model for the prevention of injury in whole populations

BACKGROUND: The World Health Organization (WHO) 'safe communities' approach to injury prevention has been embraced around the world as a model for co-ordinating community efforts to enhance safety and reduce injury. Approximately 150 communities throughout the world have formal 'Safe Communities' designation. It is of public health interest to determine to what degree the model is successful, and whether it reduces injury rates. This Cochrane Review is an update of a previous published version. OBJECTIVES: To determine the effectiveness of the WHO Safe Communities model to prevent injury in whole populations. SEARCH STRATEGY: Our search included CENTRAL, MEDLINE and EMBASE, PsycINFO, ISI Web of Science: Social Sciences Citation Index (SSCI) and ZETOC. We handsearched selected journals and contacted key people from each WHO Safe Community. The last search was December 2008. SELECTION CRITERIA: Two authors independently screened studies for inclusion. Included studies were those conducted within a WHO Safe Community that reported changes in population injury rates within the community compared to a control community. DATA COLLECTION AND ANALYSIS: Two authors independently extracted data. Meta-analysis was not appropriate due to the heterogeneity of the included studies. MAIN RESULTS: We included evaluations for 21 communities from five countries in two geographical regions in the world: Austria, Sweden and Norway, and Australia and New Zealand. Although positive results were reported for some communities, there was no consistent relationship between being a WHO designated Safe Community and subsequent changes in observed injury rates. AUTHORS' CONCLUSIONS: There is marked inconsistency in the results of the studies included in this systematic review. While the frequency of injury in some study communities did reduce following their designation as a WHO Safe Community, there remains insufficient evidence from which to draw definitive conclusions regarding the effectiveness of the model.The lack of consistency in results may be due to the heterogeneity of the approaches to implementing the model, varying efficacy of activities and strategies, varying intensity of implementation and methodological limitations in evaluations. While all communities included in the review fulfilled the WHO Safe Community criteria, these criteria were too general to prescribe a standardised programme of activity or evaluation methodology.Adequate documentation describing how various Safe Communities implemented the model was limited, making it unclear which factors affected success. Where a reduction in injury rates was not reported, lack of information makes it difficult to distinguish whether this was due to problems with the model or with the way in which it was implemented.Griffith Health, School of MedicineFull Tex
Short interfering RNA induced generation and translation of stable 5' mRNA cleavage intermediates

Sequence-specific degradation of homologous mRNA is the main mechanism by which short-interfering RNAs (siRNAs) suppress gene expression. Generally, it is assumed that the mRNA fragments resulting from Ago2 cleavage are rapidly degraded, thus making the transcript translation-incompetent. However, the molecular mechanisms involved in the post-cleavage mRNA decay are not completely understood and the fate of cleavage intermediates has been poorly studied. Using specific siRNAs and short-hairpin RNAs (shRNAs) we show that the 5′ and 3′ mRNA cleavage fragments of human papilloma virus type 16 (HPV-16) E6/7 mRNA, over-expressed in cervical malignancies, are unevenly degraded. Intriguingly, the 5′ mRNA fragment was more abundant and displayed a greater stability than the corresponding 3′ mRNA fragment in RNAi-treated cells. Further analysis revealed that the 5′ mRNA fragment was polysome-associated, indicating its active translation, and this was further confirmed by using tagged E7 protein to show that C-terminally truncated proteins were produced in treated cells. Overall, our findings provide new insight into the degradation of siRNA-targeted transcripts and show that RNAi can alter protein expression in cells as a result of preferential stabilization and translation of the 5′ cleavage fragment. These results challenge the current model of siRNA-mediated RNAi and provide a significant step forward towards understanding non-canonical pathways of siRNA gene silencing.Full Tex
TNF alpha inhibitors in Alzheimer’s disease: a systematic review

OBJECTIVES\ud
The objective of this study was to evaluate the effect of tumor necrosis factor-alpha inhibitors (TNF-I) on Alzheimer’s disease (AD)-associated pathology.\ud
DESIGN\ud
A literature search of PubMed, Embase, PsychINFO, Web of Science, Scopus and the Cochrane Library databases for human and animal studies that evaluated the use of TNF-I was performed on 26th October 2016. \ud
RESULTS\ud
The main outcomes assessed were cognition and behaviour, reduction in brain tissue mass, presence of plaques and tangles, and synaptic function. Risk of bias was assessed regarding blinding, statistical model, outcome reporting and other biases. Sixteen studies were included, 13 of which were animal studies and 3 of which were human. All animal studies found that treatment with TNF-I leads to an improvement in cognition and behaviour. None of the studies measured change in brain tissue mass. The majority of studies documented a beneficial effect in other areas, including the presence of plaques and tangles and synaptic function. The amount of data from human studies was limited. Two out of 3 studies concluded that TNF-I are beneficial in AD patients, with one being an observational study and the latter being a small pilot study, with a high risk of bias.\ud
CONCLUSION\ud
It was concluded that a large scale randomised controlled trial assessing the effectiveness of TNF-I on humans is warranted
M-theory beyond the supergravity approximation.

We analyze the four-point function of stress-tensor multiplets for the 6d quantum field theory with OSp(8∗|4) symmetry which is conjectured to be dual to M-theory on AdS7 × S4, and deduce the leading correction to the tree-level supergravity prediction by obtaining a solution of the crossing equations in the large-N limit with the superconformal partial wave expansion truncated to operators with zero spin. This correction corresponds to the M-theoretic analogue of ℛ4 corrections in string theory. We also find solutions corresponding to higher-spin truncations, but they are subleading compared to the 1-loop supergravity prediction, which has yet to be calculated
Validating a breast cancer score in Spanish women: The MCC-Spain study

A breast-risk score, published in 2016, was developed in white-American women using 92 genetic variants (GRS92), modifiable and non-modifiable risk factors. With the aim of validating the score in the Spanish population, 1,732 breast cancer cases and 1,910 controls were studied. The GRS92, modifiable and non-modifiable risk factor scores were estimated via logistic regression. SNPs without available genotyping were simulated as in the aforementioned 2016 study. The full model score was obtained by combining GRS92, modifiable and non-modifiable risk factor scores. Score performances were tested via the area under the ROC curve (AUROC), net reclassification index (NRI) and integrated discrimination improvement (IDI). Compared with non-modifiable and modifiable factor scores, GRS92 had higher discrimination power (AUROC: 0.6195, 0.5885 and 0.5214, respectively). Adding the non-modifiable factor score to GRS92 improved patient classification by 23.6% (NRI = 0.236), while the modifiable factor score only improved it by 7.2%. The full model AUROC reached 0.6244. A simulation study showed the ability of the full model for identifying women at high risk for breast cancer. In conclusion, a model combining genetic and risk factors can be used for stratifying women by their breast cancer risk, which can be applied to individualizing genetic counseling and screening recommendation
Spectral energy distribution of Markarian 501: quiescent state versus extreme outburst

The very high energy (VHE; E > 100 GeV) blazar Markarian 501 has a well-studied history of extreme spectral variability and is an excellent laboratory for studying the physical processes within the jets of active galactic nuclei. However, there are few detailed multiwavelength studies of Markarian 501 during its quiescent state, due to its low luminosity. A short-term multiwavelength study of Markarian 501 was coordinated in March 2009, focusing around a multi-day observation with the Suzaku X-ray satellite and including {\gamma}-ray data from VERITAS, MAGIC, and the Fermi Gamma-ray Space Telescope with the goal of providing a well-sampled multiwavelength baseline measurement of Markarian 501 in the quiescent state. The results of these quiescent-state observations are compared to the historically extreme outburst of April 16, 1997, with the goal of examining variability of the spectral energy distribution between the two states. The derived broadband spectral energy distribution shows the characteristic double-peaked profile. We find that the X-ray peak shifts by over two orders of magnitude in photon energy between the two flux states while the VHE peak varies little. The limited shift in the VHE peak can be explained by the transition to the Klein-Nishina regime. Synchrotron self-Compton models are matched to the data and the implied Klein-Nishina effects are explored
Near-IR imaging towards a puzzling  young stellar object precessing jet

Aims. The study of jets that are related to stellar objects in formation is important because it enables us to understand the history of how the stars have built up their mass. Many studies currently examine jets towards low-mass young stellar objects, while equivalent studies toward massive or intermediate-mass young stellar objects are rare. In a previous study, based on 12CO J = 3−2 and public near-IR data, we found highly misaligned molecular outflows toward the infrared point source UGPS J185808.46+010041.8 (IRS) and some infrared features suggesting the existence of a precessing jet. Methods. Using near-IR data acquired with Gemini-NIRI at the JHKs broad- and narrowbands centered on the emission lines of [FeII], H2 1−0 S(1), H2 2−1 S(1), Brγ, and CO 2−0 (bh), we studied the circumstellar environment of IRS with an angular resolution between 000 .35 and 000 .45. Results. The emission in the JHKs broadbands shows in great detail a cone-shaped nebula extending to the north-northeast of the point source, which appears to be attached to it by a jet-like structure. In the three bands the nebula is resolved in a twisted-shaped feature composed of two arc-like features and a bow-shock-like structure seen mainly in the Ks band, which strongly suggests the presence of a precessing jet. An analysis of proper motions based on our Gemini observations and UKIDSS data additionally supports the precession scenario. We present one of the best-resolved cone-like nebula that is most likely related to a precessing jet up to date. The analysis of the observed near-IR lines shows that the H2 is collisionally excited, and the spatially coincidence of the [FeII] and H2 emissions in the closer arc-like feature suggests that this region is affected by a J shock. The second arc-like feature presents
H2 emission without [FeII], which suggests a nondissociated C shock or a less energetic J shock. The H2 1-0 S(1) continuumsubtracted image reveals several knots and filaments at a larger spatial scale around IRS. These perfect match the distribution of the red- and blueshifted molecular outflows discovered in our previous work. An unresolved system of YSOs is suggested to explain the distribution of the analyzed near-IR features and the molecular outflows, which in turn explains the jet precession through tidal interactionsFil: Paron, Sergio Ariel. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Fariña, C.. Isaac Newton Group of Telescopes; EspañaFil: Ortega, Martin Eduardo. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; Argentin
Bibliometric tools. Evaluation, mapping

Bibliometrics is a relatively young discipline, with clear antecedents in the 1920s and a boom since the 1960s, when the name was first coined. There is a constellation of terms denoting the statistical study of (the flux of) information, most of which are used in an indiscriminate manner, as virtual synonyms. Terms such as informetrics, bibliometrics, scientometrics, webometrics, altmetrics, netometrics or cybermetrics place the focus on different approaches and/or (sub)domains of this huge research field. Thus, informetrics might be considered the umbrella term that refers to the flow of any sort of information in any mode, whereas bibliometrics restricts its interest to published information, and scientometrics focuses on the way academic/scientific information flows. Webometrics, netometrics and cybermetrics obviously study the particular conditions of exchange of information on the Internet. Altmetrics, finally, focuses on the potentialities of social media and academic social networks and tries to downplay the role played by international indexes and citation counting. Here we will use bibliometrics as our blanket term due to its focus on published information and its broad usag
Community detection as a tool for DMA identification

Water losses, the portion of water introduced in a pipe network but not consumed by users, represent a significant problem in water distribution system (WDS) management. Modern guidelines suggest to divide the pipe network in clusters, in order to compute a water balance and measure water consumption by each group. These clusters are called district metered areas (DMAs). The division of a pipe network in DMAs is usually realized with a visual exam supported by technical experience. This approach, which is convenient for small WDSs, becomes dicult to apply to large WDSs characterized by thousands of user nodes and pipes. Therefore, it is necessary to have an automatic tool to recognize the affinity degree of neighbouring nodes and to decide how to assign a node to a particular DMA. We propose an automated approach to subdivide pipes, that only requires flow rates through the network. The method has been tested to a large WDS often used as benchmark. The approach successfully divides the pipe network in an acceptable number of DMAs. Each resulting DMA is characterized by a low number of external links and by a proper number of user
Driver sleepiness—Comparisons between young and older men during a monotonous afternoon simulated drive

Young men figure prominently in sleep-related road crashes. Non-driving studies show them to be particularly vulnerable to sleep loss, compared with older men. We assessed the effect of a normal night's sleep vs. prior sleep restricted to 5 h, in a counterbalanced design, on prolonged (2 h) afternoon simulated driving in 20 younger (av. 23 y) and 19 older (av. 67 y) healthy men. Driving was monitored for sleepiness related lane deviations, EEGs were recorded continuously and subjective ratings of sleepiness taken every 200 s. Following normal sleep there were no differences between groups for any measure. After sleep restriction younger drivers showed significantly more sleepiness-related deviations and greater 4–11 Hz EEG power, indicative of sleepiness. There was a near significant increase in subjective sleepiness. Correlations between the EEG and subjective measures were highly significant for both groups, indicating good self-insight into increasing sleepiness. We confirm the greater vulnerability of younger drivers to sleep loss under prolonged afternoon driving