pinecone/core-2020-05-10-deduplication huggingface dataset:
Jet multiplicity in the proto-binary system NGC 1333-IRAS4A
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The detailed CALYPSO IRAM-PdBI view

International audienceContext. Owing to the paucity of sub-arcsecond (sub)mm observations required to probe the innermost regions of newly forming protostars, several fundamental questions are still being debated, such as the existence and coevality of close multiple systems. Aims. We study the physical and chemical properties of the jets and protostellar sources in the NGC 1333-IRAS4A proto-binary system using continuum emission and molecular tracers of shocked gas. Methods. We observed NGC 1333-IRAS4A in the SiO(6−5), SO(65−54), and CO(2−1) lines and the continuum emission at 1.3, 1.4, and 3 mm using the IRAM Plateau de Bure Interferometer in the framework of the CALYPSO large program. Results. We clearly disentangle for the first time the outflow emission from the two sources A1 and A2. The two protostellar jets have very different properties: the A1 jet is faster, has a short dynamical timescale (≲103 yr), and is associated with H2 shocked emission, whereas the A2 jet, which dominates the large-scale emission, is associated with diffuse emission, bends, and emits at slower velocities. The observed bending of the A2 jet is consistent with the change of propagation direction observed at large scale and suggests jet precession on very short timescales (~200−600 yr). In addition, a chemically rich spectrum with emission from several complex organic molecules (e.g. HCOOH, CH3OCHO, CH3OCH3) is only detected towards A2. Finally, very high-velocity shocked emission (~50 km s-1) is observed along the A1 jet. An LTE analysis shows that SiO, SO, and H2CO abundances in the gas phase are enhanced up to (3−4)×10-7, (1.4−1.7)×10-6, and (3−7.9)×10-7, respectively. Conclusions. The intrinsic different properties of the jets and driving sources in NGC 1333-IRAS4A suggest different evolutionary stages for the two protostars, with A1 being younger than A2, in a very early stage of star formation previous to the hot-corino phase
Discovery of high and very high-energy emission from the BL Lacertae object SHBL J001355.9–185406

International audienceThe detection of the high-frequency peaked BL Lac object (HBL) SHBL J001355.9–185406 (z = 0.095) at high (HE; 100 MeV < E < 300 GeV) and very high-energy (VHE; E > 100 GeV) with the Fermi Large Area Telescope (LAT) and the High Energy Stereoscopic System (H.E.S.S.) is reported. Dedicated observations were performed with the H.E.S.S. telescopes, leading to a detection at the 5.5σ significance level. The measured flux above 310 GeV is (8.3 ± 1.7stat ± 1.7sys) × 10-13 photons cm-2 s-1 (about 0.6% of that of the Crab Nebula), and the power-law spectrum has a photon index of Γ = 3.4 ± 0.5stat ± 0.2sys. Using 3.5 years of publicly available Fermi-LAT data, a faint counterpart has been detected in the LAT data at the 5.5σ significance level, with an integrated flux above 300 MeV of (9.3 ± 3.4stat ± 0.8sys) × 10-10 photons cm-2 s-1 and a photon index of Γ = 1.96 ± 0.20stat ± 0.08sys. X-ray observations with Swift-XRT allow the synchrotron peak energy in νFν representation to be located at ~1.0 keV. The broadband spectral energy distribution is modelled with a one-zone synchrotronself-Compton (SSC) model and the optical data by a black-body emission describing the thermal emission of the host galaxy. The derived parameters are typical of HBLs detected at VHE, with a particle-dominated jet
Modeling CO emission from hydrodynamic simulations of nearby spirals, starbursting mergers, and high-redshift galaxies

International audienceWe model the intensity of emission lines from the CO molecule, based on hydrodynamic simulations of spirals, mergers, and high-redshift galaxies with very high resolutions (3 pc and 103 M⊙) and detailed models for the phase-space structure of the interstellar gas including shock heating, stellar feedback processes, and galactic winds. The simulations are analyzed with a large velocity gradient (LVG) model to compute the local emission in various molecular lines in each resolution element, radiation transfer, opacity effect, and the intensity emerging from galaxies to generate synthetic spectra for various transitions of the CO molecule. This model reproduces the known properties of CO spectra and CO-to-H2 conversion factors in nearby spirals and starbursting major mergers. The high excitation of CO lines in mergers is dominated by an excess of high-density gas, and the high turbulent velocities and compression that create this dense gas excess result in broad linewidths and low CO intensity-to-H2 mass ratios. When applied to high-redshift gas-rich disks galaxies, the same model predicts that their CO-to-H2 conversion factor is almost as high as in nearby spirals, and much higher than in starbursting mergers. High-redshift disk galaxies contain giant star-forming clumps that host a high-excitation component associated to gas warmed by the spatially concentrated stellar feedback sources, although CO(1−0) to CO(3−2) emission is dominated overall by low-excitation gas around the densest clumps. These results generally highlight a strong dependence of CO excitation and the CO-to-H2 conversion factor on galaxy type, even at similar star formation rates or densities. The underlying processes are driven by the interstellar medium structure and turbulence and its response to stellar feedback, which depend on global galaxy structure and in turn affect the CO emission properties
HESS J1818-154, a new composite supernova remnant discovered in TeV gamma rays and X-rays

Composite supernova remnants (SNRs) constitute a small subclass of remnants of massive stellar explosions where non-thermal radiation is observed from both the expanding shell-like shock front and from a pulsar wind nebula (PWN) located inside of the SNR. These systems represent a unique evolutionary phase of SNRs where observations in the radio, X-ray and gamma-ray regimes allow the study of the co-evolution of both of these energetic phenomena. In this article, we report results from observations of the shell-type SNR G15.4+0.1 performed with the High Energy Stereoscopic System (H.E.S.S.) and XMM-Newton. A compact TeV gamma-ray source, HESSJ1818-154, located in the center and contained within the shell of G15.4+0.1 is detected by H.E.S.S. featuring a spectrum best represented by a power-law model with a spectral index of $-2.3 \pm 0.3_{stat} \pm 0.2_{sys}$ and an integral flux of F$(>0.42\,\mathrm{TeV}$)=($0.9 \pm 0.3_{\mathrm{stat}} \pm 0.2_{\mathrm{sys}}) \times 10^{-12}$ cm$^{-2}$ s$^{-1}$. Furthermore, a recent observation with XMM-Newton reveals extended X-ray emission strongly peaked in the center of G15.4+0.1. The X-ray source shows indications for an energy-dependent morphology featuring a compact core at energies above 4 keV and more extended emission that fills the entire region within the SNR at lower energies. Together, the X-ray and VHE gamma-ray emission provide strong evidence for the existence of a PWN located inside the shell of G15.4+0.1 and this SNR can therefore be classified as a composite based on these observations. The radio, X-ray and gamma-ray emission from the PWN is compatible with a one-zone leptonic model which requires a low average magnetic field inside the emission region. An unambiguous counterpart to the putative pulsar, thought to power the PWN, has not been detected neither in radio nor in X-ray observations of G15.4+0.1
Over-pressurized bioreactors : application to microbial cell cultures

In industrial biotechnology, microbial cultures are exposed to different local pressures inside bioreactors. Depending on the microbial species and strains, the increased pressure may have detrimental or beneficial effects on cellular growth and product formation. In this review, the effects of increased air pressure on various microbial cultures growing in bioreactors under moderate total pressure conditions (maximum, 15 bar) will be discussed. Recent data illustrating the diversity of increased air pressure effects at different levels in microbial cells cultivation will be presented, with particular attention to the effects of oxygen and carbon dioxide partial pressures on cellular growth and product formation, and the
concomitant effect of oxygen pressure on antioxidant cellular defense mechanisms.The authors thank the FCT Strategic Project PEst-OE/EQB/LA0023/2013 and the Project "BioInd-Biotechnology and Bioengineering for improved Industrial and Agro-Food processes, REF. NORTE-07-0124-FEDER-000028," cofunded by the Programa Operacional Regional do Norte (ON.2-O Novo Norte), QREN, FEDER. A special aknowledgement is given to FCT for the support to the improvement of infrastructures awarded by the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462)
Measurement of the mass difference between top and anti-top quarks in pp collisions at (√s)=7 TeV using the ATLAS detector

A measurement of the mass difference between top and anti-top quarks is presented. In a 4.7 fb−1 data sample of proton–proton collisions at √s = 7 TeV recorded with the ATLAS detector at the LHC, events consistent with ttbar production and decay into a single charged lepton final state are reconstructed. For each event, the mass difference between the top and anti-top quark candidate is calculated. A two b-tag requirement is used in order to reduce the background contribution. A maximum likelihood fit to these per-event mass differences yields Δm≣mt−mt¯ = 0.67 ± 0.61(stat) ± 0.41(syst) GeV, consistent with CPT invariance
Retreat history of the East Antarctic Ice Sheet since the Last Glacial Maximum

The East Antarctic Ice Sheet (EAIS) is the largest continental ice mass on Earth, and documenting its evolution since the Last Glacial Maximum (LGM) is important for understanding its present-day and future behaviour. As part of a community effort, we review geological evidence from East Antarctica that constrains the ice sheet history throughout this period (similar to 30,000 years ago to present). This includes terrestrial cosmogenic nuclide dates from previously glaciated regions, C-14 chronologies from glacial and post-glacial deposits onshore and on the continental shelf, and ice sheet thickness changes inferred from ice cores and continental-scale ice sheet models. We also include new C-14 dates from the George V Land Terre Adelie Coast shelf. We show that the EAIS advanced to the continental shelf margin in some parts of East Antarctica, and that the ice sheet characteristically thickened by 300-400 m near the present-day coastline at these sites. This advance was associated with the formation of low-gradient ice streams that grounded at depths of >1 km below sea level on the inner continental shelf. The Lambert/Amery system thickened by a greater amount (800 m) near its present-day grounding zone, but did not advance beyond the inner continental shelf. At other sites in coastal East Antarctica (e.g. Bunger Hills, Larsemann Hills), very little change in the ice sheet margin occurred at the LGM, perhaps because ice streams accommodated any excess ice build up, leaving adjacent, ice-free areas relatively unaffected. Evidence from nunataks indicates that the amount of ice sheet thickening diminished inland at the LGM, an observation supported by ice cores, which suggest that interior ice sheet domes were similar to 100 m lower than present at this time. Ice sheet recession may have started similar to 18,000 years ago in the Lambert/Amery glacial system, and by similar to 14,000 years ago in Mac.Robertson Land. These early pulses of deglaciation may have been responses to abrupt sea-level rise events such as Meltwater Pulse la, destabilising the margins of the ice sheet. It is unlikely, however, that East Antarctica contributed more than similar to 1 m of eustatic sea-level equivalent to post-glacial meltwater pulses. The majority of ice sheet recession occurred after Meltwater Pulse la, between similar to 12,000 and similar to 6000 years ago, during a period when the adjacent ocean warmed significantly. Large tracts of East Antarctica remain poorly studied, and further work is required to develop a robust understanding of the LGM ice sheet expansion, and its subsequent contraction. Further work will also allow the contribution of the EAIS to post-glacial sea-level rise, and present-day estimates of glacio-isostatic adjustment to be refined
Search for a W' boson decaying to a muon and a neutrino in pp collisions at √s=7 TeV

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMA new heavy gauge boson, W', decaying to a muon and a neutrino, is searched for in pp collisions at a centre-of-mass energy of 7 TeV. The data, collected with the CMS detector at the LHC, correspond to an integrated luminosity of 36 pb−1. No significant excess of events above the standard model expectation is found in the transverse mass distribution of the muon–neutrino system. Masses below 1.40 TeV are excluded at the 95% confidence level for a sequential standard-model-like W'. The W' mass lower limit increases to 1.58 TeV when the present analysis is combined with the CMS result for the electron channelWe wish to congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC machine. We thank the technical and administrative staff at CERN and other CMS institutes, and acknowledge support from: FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLPFAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTD (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA
Fetal-maternal interface impedance parallels local NADPH oxidase related superoxide production

Blood flow assessment employing Doppler techniques is a useful procedure in pregnancy evaluation, as it may predict pregnancy disorders coursing with increased uterine vascular impedance, as pre-eclampsia. While the local causes are unknown, emphasis has been put on reactive oxygen species (ROS) excessive production. As NADPH oxidase (NOX) is a ROS generator, it is hypothesized that combining Doppler assessment with NOX activity might provide useful knowledge on placental bed disorders underlying mechanisms. A prospective longitudinal study was performed in 19 normal course, singleton pregnancies. Fetal aortic isthmus (AoI) and maternal uterine arteries (UtA) pulsatility index (PI) were recorded at two time points: 20-22 and 40-41 weeks, just before elective Cesarean section. In addition, placenta and placental bed biopsies were performed immediately after fetal extraction. NOX activity was evaluated using a dihydroethidium-based fluorescence method and associations to PI values were studied with Spearman correlations. A clustering of pregnancies coursing with higher and lower PI values was shown, which correlated strongly with placental bed NOX activity, but less consistently with placental tissue. The study provides evidence favoring that placental bed NOX activity parallels UtA PI enhancement and suggests that an excess in oxidation underlies the development of pregnancy disorders coursing with enhanced UtA impedance
Antennal ampullary glands of Helicoverpa zea

In adult moths, the cephalic aorta terminates in an apical sack from which extends a pair of optic and antennal vessels that lie on either side of the esophagus, at the dorsoanterior surface of the brain. The base of each antennal vessel is dilated to form an ampulla that contains an oval mass of tissue, the antennal ampullary gland (AAG). An ultrastructural study revealed that the AAG of the corn earworm moth, Helicoverpa zea (Lepidoptera, Noctuidae), is composed of a single type of 40–50 parenchymal cells that produce secretory granules. The secretory material is released into the lymph channel of the ampullary vessel, suggesting that the AAG is an endocrine gland. Unlike the prothoracic gland and the corpus allatum, the AAG does not receive direct neural innervation; however, portions of the aortal muscle, associated with the ampullary wall, contain neurosecretory terminals and some of their products may also affect the AAG. No morphological differences were found between the AAG of males and females, with the exception that the glands in males were slightly larger. The function of the AAG remains unknown at this time. Because the AAG is located within the ampulla of the antennal vessel, one could assume that the product(s) of this gland may influence the response of the antennal sensory neurons to external stimuli
The plasters of the Sacro Monte of Varallo Sesia. From the characterization to the proposition of a restorative mix

In this paper, the systematic physical-chemical characterization of historical plasters of the Sacro Monte of Varallo Sesia, Italy, the study of the local constructive techniques, as well as the evaluation of new restoration plasters is presented. The selected samples (from XVI-XVIIIth centuries) are in a quite good state of conservation despite the prolonged exposition to weathering agents. This behavior is due to the good manufacturing and to the peculiar smooth finishing layers which reduce water permeability and allow water drops to slide off. The plasters characterization realized in laboratory for in-situ integration is also presented. These plasters should meet functional and aesthetical requirements and must satisfy the compatibility issues not only related to the physical-chemical aspect
New Challenge of the Public Buildings: nZEB Findings from IEE RePublic_ZEB Project

Nearly Zero-Energy Buildings (nZEBs) have received increased attention in recent years as a result of constant concerns for energy supply constraints, decreasing energy resources, increasing energy costs and rising impact of greenhouse gases on world climate. The EPBD recast directive [1] requests all new buildings to meet higher levels of performance than before, by exploring more the alternative energy supply systems available locally on a cost-efficiency basis and without prejudicing the occupants' comfort. To this end, after 2020, all new buildings should become "nearly zero-energy" and after 31 December 2018, the same requirement is applied for new buildings occupied and owned by public authorities. Furthermore, the EPBD recast states that MS must ensure that minimum energy performance requirements for buildings are set with a view to achieving cost-optimal levels according to the Commission Delegated Regulation (EU) No 244/2012 of 16 January 2012. In this context, the authors of this paper, who are participants in the recent started European project RePublic_ZEB, are willing to share the initial findings from ongoing research work. Public buildings constitute a specific class of buildings that require a complex analysis from the statistic point of view taking into consideration the definition and typologies and other specific parameters related with. Thus, this paper will focus on the analysis of public building stocks in the countries covered by the project consortium with the view to define relevant parameters characterizing the reference public buildings that will be considered in the further analysis regarding the assessment of cost-effective packages of solutions towards nZEB levels of performance. A review of nZEB holistic approach, definitions and existing implemented policies in the participant countries, will be presented as wel
A 119-125 GeV Higgs from a string derived slice of the CMSSM.

The recent experimental hints for a relatively heavy Higgs with a mass in the range 119-125 GeV favour supersymmetric scenarios with a large mixing in the stop mass matrix. It has been shown that this is possible in the constrained Minimal Super-symmetric Standard Model (CMSSM), but only for a very specific relation between the trilinear parameter and the soft scalar mass, favouring A ≈ −2m for a relatively light spectrum, and sizable values of tan β. We describe here a string-derived scheme in which the first condition is automatic and the second arises as a consequence of imposing radiative EW symmetry breaking and viable neutralino dark matter in agreement with WMAP constraints. More specifically, we consider modulus dominated SUSY-breaking in Type II string compactifications and show that it leads to a very predictive CMSSM-like scheme, with small departures due to background fluxes. Imposing the above constraints leaves only one free parameter, which corresponds to an overall scale. We show that in this construction  A=−3/2–√m≃−2mA=−3/2m≃−2m  and in the allowed parameter space tan β ≃ 38 − 41, leading to 119 GeV < mh  < 125 GeV. The recent LHCb results on BR(Bs → μ+μ−) further constrain this range, leaving only the region with mh ~ 125. GeV. We determine the detectability of this model and show that it could start being probed by the LHC at 7(8) TeV with a luminosity of 5(2) fb−1, and the whole parameter space would be accessible for 14 TeV and 25 fb−1. Furthermore, this scenario can host a long-lived stau with the right properties to lead to catalyzed BBN. We finally argue that anthropic arguments could favour the highest value for the Higgs mass that is compatible with neutralino dark matter, i.e., mh-125 GeV
Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival.

The cytokine TWEAK and its cognate receptor Fn14 are members of the TNF/TNFR superfamily and are upregulated in tumors. We found that Fn14, when expressed in tumors, causes cachexia and that antibodies against Fn14 dramatically extended lifespan by inhibiting tumor-induced weight loss although having only moderate inhibitory effects on tumor growth. Anti-Fn14 antibodies prevented tumor-induced inflammation and loss of fat and muscle mass. Fn14 signaling in the tumor, rather than host, is responsible for inducing this cachexia because tumors in Fn14- and TWEAK-deficient hosts developed cachexia that was comparable to that of wild-type mice. These results extend the role of Fn14 in wound repair and muscle development to involvement in the etiology of cachexia and indicate that Fn14 antibodies may be a promising approach to treat cachexia, thereby extending lifespan and improving quality of life for cancer patients
Search for excited leptons in pp collisions at √s = 7 TeV

Results are presented of a search for compositeness in electrons and muons using a data sample of pp collisions at a center-of-mass energy √s = 7 TeV collected with the CMS detector at the LHC and corresponding to an integrated luminosity of 5.0 fb[superscript −1]. Excited leptons (ℓ[superscript ⁎]) are assumed to be produced via contact interactions in conjunction with a standard model lepton and to decay via ℓ[superscript ⁎] → ℓγ, yielding a final state with two energetic leptons and a photon. The number of events observed in data is consistent with that expected from the standard model. The 95% confidence upper limits for the cross section for the production and decay of excited electrons (muons), with masses ranging from 0.6 to 2 TeV, are 1.48 to 1.24 fb (1.31 to 1.11 fb). Excited leptons with masses below 1.9 TeV are excluded for the case where the contact interaction scale equals the excited lepton mass. The limits on the cross sections are the most stringent ones published to date.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio