pinecone/core-2020-05-10-deduplication huggingface dataset:
Connectivity in MEG resting-state networks increases after resective surgery for low-grade glioma and correlates with improved cognitive performance

AbstractPurposeLow-grade glioma (LGG) patients often have cognitive deficits. Several disease- and treatment related factors affect cognitive processing. Cognitive outcome of resective surgery is unpredictable, both for improvement and deterioration, especially for complex domains such as attention and executive functioning. MEG analysis of resting-state networks (RSNs) is a good candidate for presurgical prediction of cognitive outcome. In this study, we explore the relation between alterations in connectivity of RSNs and changes in cognitive processing after resective surgery, as a stepping stone to ultimately predict postsurgical cognitive outcome.MethodsTen patients with LGG were included, who had no adjuvant therapy. MEG recording and neuropsychological assessment were obtained before and after resective surgery. MEG data were recorded during a no-task eyes-closed condition, and projected to the anatomical space of the AAL atlas. Alterations in functional connectivity, as characterized by the phase lag index (PLI), within the default mode network (DMN), executive control network (ECN), and left- and right-sided frontoparietal networks (FPN) were compared to cognitive changes.ResultsLower alpha band DMN connectivity was increased after surgery, and this increase was related to improved verbal memory functioning. Similarly, right FPN connectivity was increased after resection in the upper alpha band, which correlated with improved attention, working memory and executive functioning.DiscussionIncreased alpha band RSN functional connectivity in MEG recordings correlates with improved cognitive outcome after resective surgery. The mechanisms resulting in functional connectivity alterations after resection remain to be elucidated. Importantly, our findings indicate that connectivity of MEG RSNs may be used for presurgical prediction of cognitive outcome in future studies
Health-Related Quality of Life after Coronary Revascularization: A systematic review with meta-analysis

AbstractObjectiveTo conduct a systematic review and meta-analysis to summarize evidence and determine the impact of coronary revascularization (CR) on cardiac patients' Health-Related Quality of Life (HRQoL), highlighting factors that may affect this outcome in patients.MethodsA systematic search of Medline (Pubmed), EMBASE, Cochrane Library, Sciverse (Science Direct and Scopus) and PsycInfo was conducted to identify studies published from January 2000 to December 2012. Data were analyzed using MIX 2.0 Pro and SPSS 20.ResultsThirty-four longitudinal studies met the inclusion criteria; these studies included 15,992 patients, of whom 8,027 had undergone PCI, 6,348 had undergone CABG and 1,617 had received medication treatment. Moderate long-term effect sizes were revealed for both CR procedures. Both percutaneous coronary interventions (PCI) and coronary artery bypass graft surgery (CABG) had significantly greater effects on HRQoL than did medication; however, the CR procedures did not differ significantly from each other. Moderators included the type of instrument used to assess HRQoL and the study quality. Benefits related to physical functioning were greater than those related to psychosocial functioning in patients treated with CABG.ConclusionsEmpirical research highlights the positive effect of CR on patient HRQoL. Researchers should carefully select the instrument they use to measure HRQoL, as this may affect the results and thus conclusions. More RCTs and between-group studies employing pre-post designs should be conducted before clear conclusions can be drawn
Effectiveness of a drinking-motive-tailored emergency-room intervention among adolescents admitted to hospital due to acute alcohol intoxication — A randomized controlled trial

AbstractThe aim of this study is to develop and test the effectiveness of a drinking-motive-tailored intervention for adolescents hospitalized due to alcohol intoxication in eight cities in Germany between December 2011 and May 2012 against a similar, non-motive-tailored intervention. In a randomized controlled trial, 254 adolescents received a psychosocial intervention plus motive-tailored (intervention group; IG) or general exercises (control group; CG). Adolescents in the IG received exercises in accordance with their drinking motives as indicated at baseline (e.g. alternative ways of spending leisure time or dealing with stress). Exercises for the CG contained alcohol-related information in general (e.g. legal issues). The data of 81 adolescents (age: M=15.6, SD=1.0; 42.0% female) who participated in both the baseline and the follow-up were compared using ANOVA with repeated measurements and effect sizes (available case analyses). Adolescents reported lower alcohol use at the four-week follow-up independently of the kind of intervention. Significant interaction effects between time and IG were found for girls in terms of drinking frequency (F=7.770, p<0.01) and binge drinking (F=7.0005, p<0.05) but not for boys. For the former, the proportional reductions and corresponding effect sizes of drinking frequency (d=−1.18), binge drinking (d=−1.61) and drunkenness (d=−2.87) were much higher than the .8 threshold for large effects. Conducting psychosocial interventions in a motive-tailored way appears more effective for girls admitted to hospital due to alcohol intoxication than without motive-tailoring. Further research is required to address the specific needs of boys in such interventions. (German Clinical Trials Register, DRKS ID: DRKS00005588)
Refining light stop exclusion limits with W+W− cross sections

AbstractIf light supersymmetric top (stop) quarks are produced at the LHC and decay via on- or off-shell W-bosons they can be expected to contribute to a precision W+W− cross section measurement. Using the latest results of the CMS experiment, we revisit constraints on the stop quark production and find that this measurement can exclude portions of the parameter space not probed by dedicated searches. In particular we can exclude light top squarks up to 230 GeV along the line separating three- and four-body decays, t˜1→χ˜10W(⁎)b. We also study the exclusion limits in case when the branching ratio for these decays is reduced and show significant improvement over previously existing limits
Control of Distal-less expression in the Drosophila appendages by functional 3′ enhancers

AbstractThe expression of the Hox gene Distal-less (Dll) directs the development of appendages in a wide variety of animals. In Drosophila, its expression is subjected to a complex developmental control. In the present work we have studied a 17kb genomic region in the Dll locus which lies downstream of the coding sequence and found control elements of primary functional importance for the expression of Dll in the leg and in other tissues. Of particular interest is a control element, which we have called LP, which drives expression of Dll in the leg primordium from early embryonic development, and whose deletion causes severe truncation and malformation of the adult leg. This is the first Dll enhancer for which, in addition to the ability to drive expression of a reporter, a role can be demonstrated in the expression of the endogenous Dll gene and in the development of the leg. In addition, our results suggest that some enhancers, contrary to the widely accepted notion, may require a specific 5′ or 3′ position with respect to the transcribed region
Effect of freeze–thaw cycles on the hydraulic conductivity of a compacted clayey silt and influence of the compaction energy

AbstractCompacted clay layers are often used in impervious barrier systems to prevent the migration of water and pollutants. Environmental factors, acting during or after the clay deposition, may affect the layer integrity and induce a variation of hydraulic conductivity over time. The aim of the present research is to assess this variation when induced by freeze–thaw cycles. The paper summarizes some results of tests performed on a series of clayey silt samples, reconstituted at various levels of compaction energy and subjected to cyclic freezing according to a controlled and repeatable procedure, set to reproduce the natural environmental conditions. The hydraulic conductivity is evaluated directly from a flexible wall permeameter and indirectly from oedometric tests. The results show the consequences of cyclic freezing in relation to the compaction level and lead to insights into the development of fracture networks responsible for the increase in hydraulic conductivity
Towards a fitting procedure to deeply virtual meson production – the next-to-leading order case

AbstractBased on the collinear factorization approach, we present a comprehensive perturbative next-to-leading (NLO) analysis of deeply virtual meson production (DVMP). Our representation in conformal Mellin space can serve as basis for a global fitting procedure to access generalized parton distributions from experimental measurements of DVMP and deeply virtual Compton scattering (DVCS). We introduce a rather general formalism for the evaluation of conformal moments that can be developed further beyond the considered order. We also confirm previous diagrammatical findings in the pure singlet quark channel. Finally, we use the analytic properties of the hard scattering amplitudes to estimate qualitatively the size of radiative corrections and illustrate these considerations with some numerical examples. The results suggest that global NLO GPD fits, including both DVMP and DVCS data, could be more stable than often feared
Stau-catalyzed 6Li production in big-bang nucleosynthesis

AbstractIf the gravitino mass is in the region from a few GeV to a few 10's GeV, the scalar lepton X such as stau is most likely the next lightest supersymmetry particle. The negatively charged and long-lived X− may form a Coulomb bound state (AX−) with a nucleus A and may affect the big-bang nucleosynthesis through catalyzed fusion process. We calculate a production cross section of 6Li from the catalyzed fusion (He4X−)+d→Li6+X− by solving the Schrödinger equation exactly for three-body system of 4He, d and X. We utilize the state-of-the-art coupled-channel method, which is known to be very accurate to describe other three-body systems in nuclear and atomic reactions. The importance of the use of appropriate nuclear potential and the exact treatment of the quantum tunneling in the fusion process are emphasized. We find that the astrophysical S-factor at the Gamow peak corresponding to T=10keV is 0.038 MeV barn. This leads to the 6Li abundance from the catalyzed process as Li6|CBBN≃4.3×10−11(D/2.8×10−5)([nX−/s]/10−16) in the limit of long lifetime of X. Particle physics implication of this result is also discussed
High-pT hadron spectra, azimuthal anisotropy and back-to-back correlations in high-energy heavy-ion collisions

AbstractThe observed suppression of high-pT hadron spectra, finite azimuthal anisotropy, disappearance of jet-like back-to-back correlations, and their centrality dependence in Au+Au collisions at RHIC are shown to be quantitatively described by jet quenching within a pQCD parton model. The difference between h± and π0 suppression in intermediate pT is consistent with the observed (K+p)/π enhancement which should disappear at pT>6 GeV/c. The suppression of back-to-back correlations is shown to be directly related to the medium modification of jet fragmentation functions (FF) similar to direct-photon triggered FF's
Equivalence and embedding problems for CR-structures of any codimension

AbstractAn approach is suggested to equivalence and embedding problems for smooth CR-submanifolds of complex spaces (and, more generally, for abstract CR-manifolds) in terms of complete differential systems in jet bundles satisfied by all CR-equivalences or CR-embeddings respectively. For equivalence problems, manifolds are assumed to be of finite type and finitely nondegenerate. These are higher order generalizations of the corresponding nondegeneracy conditions for the Levi form. It is shown by a simple example that these nondegeneracy conditions cannot be even slightly relaxed to more general known conditions. In particular, for essentially finite hypersurfaces in C2, such a complete system does not exist in general. For embedding problems, source manifolds are assumed to be of finite type and their embeddings to be finitely nondegenerate. Sufficient conditions on CR-manifolds are given, where the last condition is automatically satisfied by all CR-embeddings
The prospective role of defeat and entrapment in depression and anxiety: A 12-month longitudinal study

AbstractThe concepts of “defeat” (representing failed social struggle) and “entrapment” (representing an inability to escape from a situation) have emerged from the animal literature, providing insight into the health consequences of low social rank. Evolutionary models suggest that these constructs co-occur and can lead to the development of mental disorders, although there is limited empirical evidence supporting these predictions. Participants (N=172) were recruited from economically deprived areas in North England. Over half of participants (58%) met clinical cut-offs for depression and anxiety, therefore we conducted analyses to establish whether participant outcomes were dependent on baseline defeat and entrapment levels. Participants completed measures of defeat, entrapment, depression and anxiety at two time-points twelve months apart. Factor analysis demonstrated that defeat and entrapment were best defined as one factor, suggesting that the experiences co-occurred. Regression analyses demonstrated that changes in depression and anxiety between T1 and T2 were predicted from baseline levels of defeat and entrapment; however, changes in defeat and entrapment were also predicted from baseline depression and anxiety. There are implications for targeting perceptions of defeat and entrapment within psychological interventions for people experiencing anxiety and depression and screening individuals to identify those at risk of developing psychopathology
Structural architecture and glacitectonic evolution of the Mud Buttes cupola hill complex, southern Alberta, Canada

This paper presents the results of a detailed multidisciplinary study of the deformed bedrock and overlying Quaternary sediments exposed at the Mud Buttes in southern Alberta, Canada. This large, arcuate cupola hill is composed of intensely folded and thrust sandstones, siltstones and mudstones of the Cretaceous Belly River Group. Glacitectonism responsible for the development of this internally complex landform occurred at the margin of the newly defined Prospect Valley lobe of the Laurentide Ice Sheet. Analysis of the deformation structures reveals that construction of this landform occurred in response to at least two phases of south-directed ice sheet advance separated by a period of retreat. The first phase led to the formation of a forward propagating imbricate thrust stack leading to polyphase deformation of the Belly River Group. D1 thrusting led to the detachment of thrust-bound slices of bedrock which were accreted to the base of the developing imbricate stack. This process resulted in the structurally higher and older thrust-slices being progressively “back-rotated” (tilted), accompanied by D2 thrusting and folding. Further thrusting during D3 was restricted to the core of the Mud Buttes as the deforming sequence accommodated further compression imposed by the advancing ice. Minor oscillations of the ice margin led to localised brittle-ductile shearing (D4) of the bedrock immediately adjacent to the ice contact part of the thrust stack. The second phase of ice advance led to the accretion of a relatively simple thrust and folded sequence seen the northern side of Mud Buttes. The resulting composite thrust moraine was subsequently overridden by ice advancing from the NNW to form a dome-like cupola-hill. This readvance of the Prospect Valley lobe led to the formation of a thin carapace of Quaternary sediments mantling the Mud Buttes which include glacitectonite, till and an organic-rich clay-silt (?palaeosol)
Searches for W' bosons decaying to a top quark and a bottom quark in
  proton-proton collisions at 13 TeV

Searches are presented for heavy gauge bosons decaying into a top and a
bottom quark in data collected by the CMS experiment at sqrt(s) = 13 TeV that
correspond to an integrated luminosity of 2.2 and 2.6 inverse femtobarns in the
leptonic and hadronic analyses, respectively. Two final states are analyzed,
one containing a single electron, or muon, and missing transverse momentum, and
the other containing multiple jets and no electrons or muons. No evidence is
found for a right-handed W' boson (W'[R]) and the combined analyses exclude at
95% confidence level W'[R] with masses below 2.4 TeV if M[W'[R]] >> M[nu[R]]
(mass of the right-handed neutrino), and below 2.6 TeV if M[W'[R]] < M[nu[R]].
The results provide the most stringent limits for right-handed W' bosons in the
top and bottom quark decay channel.Comment: Replaced with the published version. Added the journal reference and
  DOI. All figures and tables can be found at
  http://cms-results.web.cern.ch/cms-results/public-results/publications/B2G-16-01
Combined search for anomalous pseudoscalar HVV couplings in VH (H -> b b-bar) production and H -> VV decay

A search for anomalous pseudoscalar couplings of the Higgs boson H to electroweak vector bosons V (=W=W or Z) in a sample of proton–proton collision events corresponding to an integrated luminosity of 18.9 fb−1 at a center-of-mass energy of 8 TeV is presented. Events consistent with the topology of associated VHVH production, where the Higgs boson decays to a pair of bottom quarks and the vector boson decays leptonically, are analyzed. The consistency of data with a potential pseudoscalar contribution to the HVVHVV interaction, expressed by the effective pseudoscalar cross section fractions fa3fa3, is assessed by means of profile likelihood scans. Results are given for the VHVH channels alone and for a combined analysis of the VHVH and previously published H→VVH→VV channels. Under certain assumptions, View the MathML sourcefa3ZZ>0.0034 is excluded at 95% confidence level in the combination. Scenarios in which these assumptions are relaxed are also considered
Centrality dependence of (sic)(2S) suppression in p-Pb collisions at root s(NN)=5.02 TeV

The inclusive production of the ψ(2S) charmonium state was studied as a function of centrality in p-Pb collisions at the nucleon-nucleon center of mass energy s√NN=5.02 TeV at the CERN LHC. The measurement was performed with the ALICE detector in the center of mass rapidity ranges −4.46 < ycms< −2.96 and 2.03 < ycms< 3.53, down to zero transverse momentum, by reconstructing the ψ(2S) decay to a muon pair. The ψ(2S) production cross section σψ(2S) is presented as a function of the collision centrality, which is estimated through the energy deposited in forward rapidity calorimeters. The relative strength of nuclear effects on the ψ(2S) and on the corresponding 1S charmonium state J/ψ is then studied by means of the double ratio of cross sections [σψ(2S)/σJ/ψ]pPb/[σψ(2S)/σJ/ψ]pp between p-Pb and pp collisions, and by the values of the nuclear modification factors for the two charmonium states. The results show a large suppression of ψ(2S) production relative to the J/ψ at backward (negative) rapidity, corresponding to the flight direction of the Pb-nucleus, while at forward (positive) rapidity the suppressions of the two states are comparable. Finally, comparisons to results from lower energy experiments and to available theoretical models are presented
Uncertainty in competitive bidding – a framework for product–service systems

This article was published in the journal Production Planning and Control [© Taylor and Francis]. The definitive version is available at: http://www.tandfonline.com/doi/abs/10.1080/09537287.2012.705354Owing to servitisation, manufacturing companies are increasingly required to compete through the provision of services around their products. The contracts for these services are often allocated through competitive bidding where the potential suppliers submit a price bid to the customer. The pricing decision is influenced by various uncertainties. This article proposes a conceptual framework depicting these influencing uncertainties on the bidding strategy. This framework is based on three empirical studies with industry investigating different viewpoints on the decision-making process. The intention is to support the pricing decision when competitively bidding for a service contract. The framework can be applied to specific competitive bidding situations to identify the influencing uncertainties, model them and depict their influences on the pricing decision
Kernel functions Backlund transformations for relativistic Calogero-Moser Toda systems

This article was published in the Journal of Mathematical Physics [© American Institute of Physics] and the definitive version is available at: http://dx.doi.org/10.1063/1.4764878We obtain kernel functions associated with the quantum relativistic Toda systems,\ud
both for the periodic version and for the nonperiodic version with its dual. This\ud
involves taking limits of previously known results concerning kernel functions for\ud
the elliptic and hyperbolic relativistic Calogero-Moser systems. We show that the\ud
special kernel functions at issue admit a limit that yields generating functions of\ud
Bäcklund transformations for the classical relativistic Calogero-Moser and Toda\ud
systems. We also obtain the nonrelativistic counterparts of our results, which tie\ud
in with previous results in the literature
Clinically indicated replacement versus routine replacement of peripheral venous catheters (Review)

Background\ud
Centers for Disease Control Guidelines recommend replacement of peripheral intravenous (IV) catheters every 72 to 96 hours. Routine replacement is thought to reduce the risk of phlebitis and bacteraemia. Catheter insertion is an unpleasant experience for patients and replacement may be unnecessary if the catheter remains functional and there are no signs of inflammation. Costs associated with routine replacement may be considerable.\ud
\ud
Objectives\ud
To assess the effects of removing peripheral IV catheters when clinically indicated compared with removing and re-siting the catheter routinely.\ud
\ud
\u
Equatorial locations of water on Mars : improved resolution maps based on Mars Odyssey Neutron Spectrometer data.

We present a map of the near subsurface hydrogen distribution on Mars, based on epithermal neutron data from the Mars Odyssey Neutron Spectrometer. The map’s spatial resolution is approximately improved two-fold via a new form of the pixon image reconstruction technique. We discover hydrogen-rich mineralogy far from the poles, including  ∼10 wt.% water equivalent hydrogen (WEH) on the flanks of the Tharsis Montes and  >40 wt.% WEH at the Medusae Fossae Formation (MFF). The high WEH abundance at the MFF implies the presence of bulk water ice. This supports the hypothesis of recent periods of high orbital obliquity during which water ice was stable on the surface. We find the young undivided channel system material in southern Elysium Planitia to be distinct from its surroundings and exceptionally dry; there is no evidence of hydration at the location in Elysium Planitia suggested to contain a buried water ice sea. Finally, we find that the sites of recurring slope lineae (RSL) do not correlate with subsurface hydration. This implies that RSL are not fed by large, near-subsurface aquifers, but are instead the result of either small ( < 120 km diameter) aquifers, deliquescence of perchlorate and chlorate salts or dry, granular flows