pinecone/core-2020-05-10-deduplication huggingface dataset:
Some Insights into Formamide Formation through Gas-phase Reactions in the Interstellar Medium

Producción CientíficaWe study the viability of different gas-phase ion–molecule reactions that could produce precursors of formamide in the interstellar medium. We analyze different reactions between cations containing a nitrogen atom (NH+3 , NH+4 , NH3OH+, and NH2OH+) and neutral molecules having one carbonyl group (H2CO and HCOOH). First, we report a theoretical estimation of the reaction enthalpies for the proposed processes. Second, for more favorable reactions, from a thermodynamic point of view, we perform a theoretical study of the potential energy surface. In particular, the more exothermic processes correspond to the reactions of ionized and protonated hydroxylamine with formaldehyde. In addition, a neutral–neutral reaction has also been considered. The analysis of the potential energy surfaces corresponding to these reactions shows that these processes present a net activation barrier and that they cannot be considered as a source of formamide in space.Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA330U13
Structure and spectroscopic properties of neutral and cationic tetratomic [C,H,N,Zn] isomers: A theoretical study

Producción CientíficaThe structure and spectroscopic parameters of the most relevant [C,H,N,Zn] isomers have been studied employing high-level quantum chemical methods. For each isomer, we provide predictions for their molecular structure, thermodynamic stabilities as well as vibrational and rotational spectroscopic parameters which could eventually help in their experimental detection. In addition, we have carried out a detailed study of the bonding situations by means of a topological analysis of the electron density in the framework of the Bader’s quantum theory of atoms in molecules.
The analysis of the relative stabilities and spectroscopic parameters suggests two linear isomers of the neutral [C,H,N,Zn] composition, namely, cyanidehydridezinc HZnCN (1Σ) and hydrideisocyanidezinc HZnNC (1Σ), as possible candidates for experimental detections. For the cationic [C,H,N,Zn]+ composition, the most stable isomers are the ion-molecule complexes arising from the direct interaction of the zinc cation with either the nitrogen or carbon atom of either hydrogen cyanide or hydrogen isocyanide, namely, HCNZn+ (2Σ) and HCNZn+ (2Σ).Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA330U13
A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

A recent meta-analysis of multiple genome-wide association and follow-up endometrial cancer case-control datasets identified a novel genetic risk locus for this disease at chromosome 14q32.33. To prioritize the functional SNP(s) and target gene(s) at this locus, we employed an in silico fine-mapping approach using genotyped and imputed SNP data for 6,608 endometrial cancer cases and 37,925 controls of European ancestry. Association and functional analyses provide evidence that the best candidate causal SNP is rs2494737. Multiple experimental analyses show that SNP rs2494737 maps to a silencer element located within AKT1, a member of the PI3K/AKT/MTOR intracellular signaling pathway activated in endometrial tumors. The rs2494737 risk A allele creates a YY1 transcription factor-binding site and abrogates the silencer activity in luciferase assays, an effect mimicked by transfection of YY1 siRNA. Our findings suggest YY1 is a positive regulator of AKT1, mediating the stimulatory effects of rs2494737 increasing endometrial cancer risk. Identification of an endometrial cancer risk allele within a member of the PI3K/AKT signaling pathway, more commonly activated in tumors by somatic alterations, raises the possibility that well tolerated inhibitors targeting this pathway could be candidates for evaluation as chemopreventive agents in individuals at high risk of developing endometrial cancer
Isoperimetric inequalities in graphs and surfaces

Let M be the set of metric spaces that are either graphs with bounded degree or Riemannian manifolds with bounded geometry. Kanai proved the quasi-isometric stability of several geometric properties (in particular, of isoperimetric inequalities) for the spaces in M. Kanai proves directly these results for graphs with bounded degree; in order to prove the general case, he uses a graph (an ?-net) associated to a Riemannian manifold with bounded geometry. This paper studies the stability of isoperimetric inequalities under quasi-isometries between non-exceptional Riemann surfaces (endowed with their Poincare metrics). The present work proves the stability of the linear isoperimetric inequality for planar surfaces (genus zero surfaces) without the condition on bounded geometry. It is also shown the stability of any non-linear isoperimetric inequality
Modeling and evolving biochemical networks: insights into\ud
communication and computation from the biological domain

This paper is concerned with the modeling and evolving\ud
of Cell Signaling Networks (CSNs) in silico. CSNs are\ud
complex biochemical networks responsible for the coordination of cellular activities. We examine the possibility to computationally evolve and simulate Artificial Cell Signaling Networks (ACSNs) by means of Evolutionary Computation techniques. From a practical point of view, realizing and evolving ACSNs may provide novel computational paradigms for a variety of application areas. For example, understanding some inherent properties of CSNs such as crosstalk may be of interest: A potential benefit of engineering crosstalking systems is that it allows the modification of a specific process according to the state of other processes in the system. This is clearly necessary in order to achieve complex control tasks. This work may also contribute to the biological understanding of the origins and evolution of real CSNs. An introduction to CSNs is first\ud
provided, in which we describe the potential applications\ud
of modeling and evolving these biochemical networks in\ud
silico. We then review the different classes of techniques to model CSNs, this is followed by a presentation of two alternative approaches employed to evolve CSNs within the\ud
ESIGNET project. Results obtained with these methods\ud
are summarized and discussed
Exploring the role of usability in the software process:\ud
a study of Irish software SMEs

This paper explores the software processes and usability techniques used by Small and Medium Enterprises (SMEs) that develop web applications.  The significance of this research is that it looks at development processes used by SMEs in order to assess to what degree usability is integrated into the process.  This study seeks to gain an understanding into the level of awareness of usability within SMEs today and their commitment to usability in practice.  The motivation for this research is to explore the current development processes used by SMEs in developing web applications and to understand how usability is represented in those processes.  The background for this research is provided by the growth of the web application industry beyond informational web sites to more sophisticated applications delivering a broad range of functionality. This paper presents an analysis of the practices of several Irish SMEs that develop web applications through a series of case studies. With the focus on SMEs that develop web applications as Management Information Systems and not E-Commerce sites, informational sites, online communities or web portals. This study gathered data about the usability techniques practiced by these companies and their awareness of usability in the context of the software process in those SMEs. The contribution of this study is to further the understanding of the current role of usability within the software development processes of SMEs that develop web applications
Structural properties of GaAsN/GaAs quantum wells studied at the atomic scale by cross-sectional scanning tunnelling microscopy

The nitrogen distribution in GaAsNGaAs quantum wells _QWs_ grown by molecular beam epitaxy is studied on the atomic scale by cross-sectional scanning tunneling microscopy. No nitrogen clustering is observed in the range of N contents studied _between 1.0% and 2.5%, as measured by counting the individual N atoms inside the QW_. Nevertheless, the upper interface roughness increases with the amount of N. A residual N concentration in the GaAs barriers is found, which strongly increases with the amount of N in the QW
Potassium fertilisation and the thermal behaviour of Cynara cardunculus L.

Herbaceous biomass like Cynara is commonly high in potassium, chlorine and ash, which has been reported as a source of problems for combustion applications. An appropriate management of the potassium fertilisation is suggested as a way of improving the quality of the Cynara biomass for solid fuel applications. In this work a factorial experiment was designed involving two types of fertilisers, KCl and K2SO4, and two K rates, in order to study the effect of potassium fertilisation on the composition and thermal behaviour of Cynara biomass.\ud
The results proved that the potassium content of Cynara biomass increases with the potassium fertilisation. The thermogravimetric study showed that sintering phenomena can be expected at temperatures higher than 900 °C when the crop has been highly K-fertilised, irrespective of the type of fertiliser used, KCl or K2SO4. However, the SEM images taken of samples of the four K treatments of this experiment did not reveal signs of ash melting, although some particles with crystalline appearance appeared in the samples from highly K-fertilised treatments
Cubic and hexagonal InGaAsN dilute arsenides by unintentional homogeneous incorporation of As into InGaN

Arsenic alloying is observed for epitaxial layers nominally intended to be In0.75Ga0.25N. Voids form beneath their interfaces with GaAs substrates, acting as sources of Ga + As out-diffusion into the growing epilayers. As a result, heteroepitaxial single-phase quaternary InxGa1-xAsyN1-y, films are formed with x similar to 0.55 and 0.05 menor que y menor que 0,10. While an undoped epilayer retains the wurtzite structure, a Mn-doped sample showed randomly spaced dopant segregations, which, together with a slightly higher As concentration, led to a transformation from the hexagonal to the twinned cubic phase
The effect of gamma-cyclodextrin addition in the self-assembly behavior of pyrene labeled poly(acrylic) acid with different chain sizes

The interaction between poly(acrylic acid) polymers (PAA) of low- (2000 g/mol) and high- (450,000 g/mol) molecular weight (Mw) hydrophobically modified with pyrene (PAAMePy) and beta- and gamma-cyclodextrins (beta-CD, gamma-CD) was investigated with fluorescent techniques. The interaction with beta-CD promotes little variation in the spectral and photophysical behavior of the polymer, whereas significant changes are observed upon addition of gamma-CD. The degree of inclusion (between the pyrene groups of the polymer and the cyclodextrins) is followed through the observation of the changes in the absorption, excitation (collected in the monomer and excimer emission regions) and emission (IE/IM ratio) spectra and from time-resolved data. Within the studied range of gamma-CD concentration, the fluorescence decays of the long chain (high Mw) PAAMePy polymers were found tri-exponential in the monomer and excimer emission regions in agreement with previous studies. In the case of the low Mw PAAMePy polymers, tri-exponential decays were observed at the monomer and excimer emission wavelengths. However, when a gamma-CD concentration of 0.01 and 0.03 M is reached for, respectively, the low- and high-labeled pyrene short chain (low Mw) polymers, the fluorescence decays in the excimer region become biexponential (two excimers) with no rising component, thus showing that all pyrene groups are encapsulated (and preassociated) into the gamma-CD cavity. In the case of the high Mw polymers, the addition of gamma-CD has been found to change the level of polymer interaction from pure intramolecular (water in the absence of cyclodextrin) to a coexistence of intra- with intermolecular interactions. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 1402-1415, 2008http://dx.doi.org/10.1002/pola.2248
Deposition of hydroxyapatite on SiC nanotubes in simulated body fluid

SiC nanotubes can become candidate reinforcement materials for dental and orthopedic implants due to their light weight and excellent mechanical properties. However, the development of bioactive SiC materials has not been reported. In this study, hydroxyapatites were found on SiC nanotubes treated with NaOH and subsequently HCl solution after soaking in simulated body fluid. On the other hand, hydroxyapatites did not deposit on as-received SiC nanotubes, the SiC nanotubes with NH4OH solution treatment and SiC bulk materials with NaOH and subsequently HCl solution treatment. Therefore, we succeeded in the development of bioactive SiC nanotubes by downsizing SiC materials to nanometer size and treating with NaOH and subsequently HCl solutions for the first time
Web 2.0, language resources and standards to automatically build a multilingual named entity lexicon

This paper proposes to advance in the current state-of-the-art of automatic Language Resource (LR) building by taking into consideration three elements: (i) the knowledge available in existing LRs, (ii) the vast amount of information available from the collaborative paradigm that has emerged from the Web 2.0 and (iii) the use of standards to improve interoperability. We present a case study in which a set of LRs for diﬀerent languages (WordNet for English and Spanish and Parole-Simple-Clips for Italian) are\ud
extended with Named Entities (NE) by exploiting Wikipedia and the aforementioned LRs. The practical result is a multilingual NE lexicon connected to these LRs and to two ontologies: SUMO and SIMPLE. Furthermore, the paper addresses an important problem which aﬀects the Computational Linguistics area in the present, interoperability, by making use of the ISO LMF standard to encode this lexicon. The diﬀerent steps of the procedure (mapping, disambiguation, extraction, NE identiﬁcation and postprocessing) are comprehensively explained and evaluated. The resulting resource contains 974,567, 137,583 and 125,806 NEs for English, Spanish and Italian respectively. Finally, in order to check the usefulness of the constructed resource, we apply it into a state-of-the-art Question Answering system and evaluate its impact; the NE lexicon improves the system’s accuracy by 28.1%. Compared to previous approaches to build NE repositories, the current proposal represents a step forward in terms of automation, language independence, amount of NEs acquired and richness of the information represented
The aggressiveness of pig slurry to cement mortars

The aim was to measure the behaviour of various mortars employed in livestock media in central Spain and to analyse the aggressiveness of pig slurry to cement blended with fly ash mortars. To achieve this, mortar specimens were immersed in ponds storing pig slurry.  Mortar specimens, of 40 ? 40 ? 160 mm, were made from four types of cement commonly used and recommended for rural areas. The types were a sulphate-resistant Portland cement and three cements blended in different proportions with fly ash and limestone filler. After 3, 6, 12, 24, 36, 48 and 60 months of exposure, three or four specimens of each cement type were removed from the pond and washed with water. Their compressive strength and microstructure (X-ray diffraction, mercury intrusion pore-symmetry, thermal analysis and scanning electron microscopy) were then measured. Sulphate-resistant Portland cement (SR-PC), found to be more susceptible to degradation due to its greater proportion of macro-pores and increased total porosity, was found not to be suitable for use with livestock. After 60 months of immersion in the pig slurry medium, CEM II-A (40.3%) mortar retained the greatest compressive strength. Mortars with less than 20% replacement of cement by fly ash were found to be the most durable, with the most suitable mechanical behaviour
DROMO formulation for planar motions: Solution to the Tsien Problem

The two-body problem subject to a constant radial thrust is analyzed as a planar motion. The description of the problem is performed in terms of three perturbation methods: DROMO and two others due to Deprit. All of them rely on Hansen?s ideal frame concept. An explicit, analytic, closed-form solution is obtained for this problem when the initial orbit is circular (Tsien problem), based on the DROMO special perturbation method, and expressed in terms of elliptic integral functions. The analytical solution to the Tsien problem is later used as a reference to test the numerical performance of various orbit propagation methods, including DROMO and Deprit methods, as well as Cowell and Kustaanheimo?Stiefel methods
Identification of a major QTL for Xanthomonas arboricola pv. pruni resistance in apricot

Xanthomonas arboricola pv. pruni causes bacterial spot of stone fruit resulting in severe yield losses in apricot production systems. Present on all continents, the pathogen is regulated in Europe as a quarantine organism. Host resistance is an important component of integrated pest management; however, little work has been done describing resistance against X. arboricola pv. pruni. In this study, an apricot population derived from the cross “Harostar” × “Rouge de Mauves” was used to construct two parental genetic maps and to perform a quantitative trait locus analysis of resistance to X. arboricola pv. pruni. A population of 101 F1 individuals was inoculated twice for two consecutive years in a quarantine greenhouse with a mixture of bacterial strains, and disease incidence and resistance index data were collected. A major QTL for disease incidence and resistance index accounting respectively for 53 % (LOD score of 15.43) and 46 % (LOD score of 12.26) of the phenotypic variation was identified at the same position on linkage group 5 of “Rouge de Mauves.” Microsatellite marker UDAp-452 co-segregated with the resistance, and two flanking microsatellites, namely BPPCT037 and BPPCT038A, were identified. When dividing the population according to the alleles of UDAp-452, the subgroup with unfavorable allele had a disease incidence of 32.6 % whereas the group with favorable allele had a disease incidence of 21 %, leading to a reduction of 35.6 % in disease incidence. This study is a first step towards the marker-assisted breeding of new apricot varieties with an increased tolerance to X. arboricola pv. pruni
Abdominal exercises affect inter-rectus distance in postpartum women: a two-dimensional ultrasound study

I Brage finner du siste tekst-versjon av artikkelen, og den kan inneholde ubetydelige forskjeller fra forlagets pdf-versjon. Forlagets pdf-versjon finner du på www.sciencedirect.com: http://dx.doi.org/10.1016/j.physio.2015.04.004 / In Brage you'll find the final text version of the article, and it may contain insignificant differences from the journal's pdf version. The definitive version is available at www.sciencedirect.com: http://dx.doi.org/10.1016/j.physio.2015.04.004Objectives:

To compare inter-rectus distance (IRD) at rest between women who had a vaginal delivery with women who had a caesarean section, and to describe the effect of different abdominal exercises on IRD.

Setting:

Physiotherapy practice.

Design:

Cross-sectional experimental study.

Participants:

Thirty-eight postpartum primiparous mothers with a singleton baby (vaginal delivery: n = 23; caesarean section: n = 15).

Interventions:

Two-dimensional ultrasound images from the abdominal wall were recorded at rest and at the end position of abdominal crunch, drawing-in and drawing-in + abdominal crunch exercises. IRD measurements at rest, above and below the umbilicus, were compared between the two groups (vaginal delivery and caesarean section). IRD was also measured above and below the umbilicus during three abdominal exercises in both groups.

Main outcome measures:

IRD 2 cm above and below the umbilicus.

Results:

No significant differences in IRD, either above or below the umbilicus, were found between the vaginal delivery and caesarean section groups. IRD above the umbilicus was significantly reduced during abdominal crunch exercises compared with at rest {mean 21.7 [standard deviation (SD) 7.6] mm vs 25.9 (SD 9.0) mm; mean difference 4.2 mm; 95% confidence interval (CI) 0.5 to 7.9}. IRD below the umbilicus was significantly greater during drawing-in exercises compared with at rest [16.0 (SD 8.1) mm vs 11.4 (SD 4.9) mm; mean difference 4.5 mm; 95% CI 1.6 to 7.4].

Conclusion:

In contrast to existing recommendations for abdominal strength training among postpartum women, this study found that abdominal crunch exercises reduced IRD, and drawing-in exercises were ineffective for reducing IRD. Further basic studies and randomised controlled trials are warranted to explore the effect of abdominal training on IRD.Seksjon for idrettsmedisinske fag / Department of Sports Medicin
Legal implications of range expansions in a terrestrial carnivore: the case of the golden jackal (Canis aureus) in Europe

Due to global environmental changes, species are appearing more frequently in
places where they have not previously occurred, and this trend is expected to continue.
Such range expansions can create considerable challenges and confusion for management
and policy, especially for species associated with conflicts and whose management is
influenced by international legal frameworks. The golden jackal (Canis aureus) in Europe
represents a good case study to address the questions related to management of naturally
expanding species. We review the recent expansion of the golden jackal across the continent,
and address several ensuing policy and legal questions that also have clear implications
for other expanding species. To that end, we analyze the EU Habitats Directive and
several other international legal instruments including the Convention on Biological
Diversity and the Bern Convention on European Wildlife. We also review the status of the
golden jackal under national legislation and highlight some of the management confusion
due to recent range expansion and inadequate legal interpretation. Specific questions we
address include in which cases an expanding species is to be considered an (invasive) alien
species in countries where it did not formerly occur; what countries’ conservation obligations
are with respect to expanding species; what difference it makes for those obligations
whether or not a species historically occurred in a country; what scope exists for
lethal control of its populations; what the prospects are for transboundary cooperation at
the population level; and what responses are required when colonizing species hybridise
with other wildlife or domestic animals
Time exponential splitting technique for the Klein-Gordon equation with Hagstrom-Warburton high-order absorbing boundary conditions

Producción CientíficaKlein–Gordon equations on an unbounded domain are considered in one dimensional and two dimensional cases. Numerical computation is reduced to a finite domain by using the Hagstrom–Warburton (H-W) high-order absorbing boundary conditions (ABCs). Time integration is made by means of exponential splitting schemes that are efficient and easy to implement. In this way, it is possible to achieve a negligible error due to the time integration and to study the behavior of the absorption error. Numerical experiments displaying the accuracy of the numerical solution for the two dimensional case are provided. The influence of the dispersion coefficient on the error is also studied.This work has obtained financial support from project MTM2011-23417 of Ministerio de Economía y Competitividad