pinecone/core-2020-05-10-deduplication huggingface dataset:
Core excitations across the neutron shell gap in Tl-207

The single closed-neutron-shell, one proton-hole nucleus <sup>207</sup>Tl was populated in deep-inelastic collisions of a <sup>208</sup>Pb beam with a <sup>208</sup>Pb target. The yrast and near-yrast level scheme has been established up to high excitation energy, comprising an octupole phonon state and a large number of core excited states. Based on shell-model calculations, all observed single core excitations were established to arise from the breaking of the N=126 neutron core. While the shell-model calculations correctly predict the ordering of these states, their energies are compressed at high spins. It is concluded that this compression is an intrinsic feature of shell-model calculations using two-body matrix elements developed for the description of two-body states, and that multiple core excitations need to be considered in order to accurately calculate the energy spacings of the predominantly three-quasiparticle states
Lipschitz and Hölder stability of optimization problems and generalized equations

This paper studies stability aspects of solutions of parametric mathematical programs and generalized equations, respectively, with disjunctive constraints. We present sufficient conditions that, under some constraint qualifications ensuring metric subregularity of the constraint mapping, continuity results of upper Lipschitz and upper Hölder type, respectively, hold. Furthermore, we apply the above results to parametric mathematical programs with equilibrium constraints and demonstrate, how some classical results for the nonlinear programming problem can be recovered and even improved by our theory
MAGIC search for VHE gamma-ray emission from AE Aquarii in a multiwavelength context

Context: The nova-like cataclysmic variable (CV) AE Aquarii (AE Aqr) has been claimed to be a very-high-energy (VHE, E &gt;100 GeV) source both on observational and theoretical grounds. Aims: To search for TeV gamma-ray emission from AE Aqr during different states of the source at several wavelengths and to confirm or rule out previous claims of detection of gamma-ray emission from this object. Methods: We report on observations of AE Aqr performed by MAGIC. The source was observed during 12 hours as a part of a multiwavelength campaign carried out between May and June 2012 covering the optical, X-ray and gamma-ray ranges. Besides MAGIC, the other facilities involved were KVA, Skinakas and Vidojevica telescopes in the optical and Swift in X-rays. Results: AE Aqr was not detected at VHE energies during the multiwavelength campaign. We establish integral upper limits at the 95% confidence level for the steady emission assuming the differential flux proportional to a power-law function dPHI/dE ~ E^(−GAMMA), with a Crab-like photon spectral index of GAMMA=2.6. The upper limit above 200 GeV is 6.4 x 10^(−12) cm^(−2) s^(−1) and above 1 TeV is 7.4 x 10^(−13) cm^(−2) s^(−1). We calculate integral upper limits coincident with different states of the source in the optical. We have also computed upper limits to the pulsed emission limiting the signal region to 30% of the phaseogram and obtaining an upper limit for the pulsed emission of 2.6 x 10^(−12) cm^(−2) s^(−1) for energies above 200 GeV. Finally, we search for pulsed emission at different frequencies applying the Rayleigh test and do not find any significant signal. Conclusions: Our results indicate that AE Aqr is not a very high energy gamma-ray emitter at the level of emission previously claimed. We have established the most constraining upper limits for the TeV gamma-ray emission of AE Aqr
Hot medium effects on J/ψ production in p+Pb collisions at sNN‾‾‾‾√=5.02TeV

Based on a kinetic description of J/ψ dissociation and production in an expanding quark–gluon plasma that is described by a 2+1 dimensional ideal hydrodynamics, we have studied the hot medium effects on J/ψ production in p+Pb collisions at sNN‾‾‾‾√=5.02TeV . Including also the cold nuclear matter effects, we are able to reproduce recent experimental results on the nuclear modification factor RpPb(J/ψ) measured by the ALICE Collaboration. We have also made predictions for the RpPb of J/ψ and the double ratio RpropPb(ψ′)/RpropPb(J/ψ) of prompt quarkonia produced in the most central 10% p+Pb collisions. We find that different from the cold nuclear matter effects, the RpPb(J/ψ) is slightly smaller than that in the minimum bias collisions, and the double ratio is significantly less than one at backward rapidity
Resurgence and the Nekrasov-Shatashvili limit: connecting weak and strong coupling in the Mathieu and Lamé systems

The Nekrasov-Shatashvili limit for the low-energy behavior of N = 2 $$ \mathcal{N}=2 $$ and N = 2 * $$ \mathcal{N}={2}^{*} $$ supersymmetric SU(2) gauge theories is encoded in the spectrum of the Mathieu and Lamé equations, respectively. This correspondence is usually expressed via an all-orders Bohr-Sommerfeld relation, but this neglects non-perturbative effects, the nature of which is very different in the electric, magnetic and dyonic regions. In the gauge theory dyonic region the spectral expansions are divergent, and indeed are not Borel-summable, so they are more properly described by resurgent trans-series in which perturbative and non-perturbative effects are deeply entwined. In the gauge theory electric region the spectral expansions are convergent, but nevertheless there are non-perturbative effects due to poles in the expansion coefficients, and which we associate with worldline instantons. This provides a concrete analog of a phenomenon found recently by Drukker, Mariño and Putrov in the large N expansion of the ABJM matrix model, in which non-perturbative effects are related to complex space-time instantons. In this paper we study how these very different regimes arise from an exact WKB analysis, and join smoothly through the magnetic region. This approach also leads to a simple proof of a resurgence relation found recently by Dunne and Ünsal, showing that for these spectral systems all non-perturbative effects are subtly encoded in perturbation theory, and identifies this with the Picard-Fuchs equation for the quantized elliptic curve
Perpetual American options in diffusion-typemodels with running maxima and drawdowns

We study perpetual American option pricing problems in an extension of the Black-Merton-Scholes model in which the dividend and volatility rates of the underlying risky asset depend on the running values of its maximum and maximum drawdown. The optimal exercise times are shown to be the first times at which the underlying asset hits certain boundaries depending on the running values of the associated maximum and maximum drawdown processes. We obtain closed-form solutions to the equivalent free-boundary problems for the value functions with smooth fit at the optimal stopping boundaries and normal reflection at the edges of the state space of the resulting three-dimensional Markov process. The optimal exercise boundaries for the perpetual American options on the maximum of the market depth with fixed and  oating strikes are determined as the minimal solutions of certain first-order nonlinear ordinary differential equations
CP violation and limits on New Physics including recent Bs measurements

20 pages, 13 figures.-- ISI Article Identifier: 000245765000001.-- ArXiv pre-print available at: http://arxiv.org/abs/hep-ph/0608100Printed version published on Apr 16, 2007.We analyse present constraints on the SM parameter space and derive, in a model independent way, various bounds on New Physics contributions to Bd(0)-(B)over-bar(0)(d) and Bs(0)-(B)over-bar(0)(s) mixings. Our analyses include information on a large set of asymmetries, leading to the measurement of the CKM phases γ and (β)over-bar, as well as recent data from D0 and CDF related to the Bs(0)-(B)over-bar(0)(s) system such as the measurement of ΔMBs, A and ΔΓ(CP)(s). We examine in detail several observables such as the asymmetries A(sl)(d), A, the width differences ΔΓ(d) and ΔΓ(CP)(S) and discuss the role they play in establishing the limits on New Physics. The present data clearly favour the SM, with the New Physics favoured region placed around the SM solution. A New Physics solution significantly different from the SM is still allowed, albeit quite disfavoured (2.6% probability). We analyse the presently available indirect knowledge on the phase (Χ)over-bar entering in Bs(0)-Bs(0) mixing and study the impact of a future measurement of (Χ)over-bar to be achieved at LHC, through the measurement of the time-dependent CP asymmetry in Bs -> J/Ψ Θ decays.This research has been supported by European FEDER, Spanish MEC under grant FPA 2005-01678, Generalitat Valenciana under GVACOMP 2006-214, by Fundação para a Ciência e a Tecnologia (FCT, Portugal) through the projects POCTI/FNU/44409/2002, PDCT/FP/FNU/50250/2003, POCI/FP/63415/2005, POCTI/FP/FNU/50167/2003, CFTP-FCT UNIT 777, and by Acção Integrada Luso-Espanhola E73/04. M.N. acknowledges financial support from FCT.Peer reviewe
Strange particle production in pp collisions at ps = 0.9 and 7 TeV

The spectra of strange hadrons are measured in proton-proton collisions, recorded by the CMS experiment at the CERN LHC, at centre-of-mass energies of 0.9 and 7 TeV. The \textK\textS0 K0S, Λ, and Ξ− particles and their antiparticles are reconstructed from their decay topologies and the production rates are measured as functions of rapidity and transverse momentum, p T. The results are compared to other experiments and to predictions of the Pythia Monte Carlo program. The p T distributions are found to differ substantially from the Pythia results and the production rates exceed the predictions by up to a factor of three.Peer Reviewe
Efeitos da pregabalina sobre alterações comportamentais induzidas pela cetamina em ratos

Objective: The aim of this study is to investigate the effects of pregabalin on the behavior of rats under the influence of ketamine, an NMDA receptor antagonist that mimics the symptoms of schizophrenia. Methods: Rats were injected with saline or 25 mg/kg ketamine intraperitoneally. After that, behavior modifications were investigated by the evaluation of stereotypy and hyperlocomotion, after treating rats with pregabalin (at doses of 30 mg/kg or 100 mg/kg) or placebo (saline solution). Results: The administration of pregabalin reduced ketamine-induced hyperlocomotion. However, neither doses of pregabalin had a significant effect on ketamine-induced stereotypy. Conclusion: This is the first study to investigate the effects of pregabalin using an animal model of psychosis. Furthermore, our results indicate that behavioral changes induced by ketamine in rats can be reversed with the use of pregabalin, suggesting its potential to treat psychotic symptoms.Objetivo: O presente estudo tem como objetivo investigar os efeitos da pregabalina sobre as alterações comportamentais em ratos induzidas pela cetamina, um antagonista do receptor glutamatérgico NMDA, utilizado em modelos animais de psicose. Métodos:\ud
Ratos receberam injeção com solução salina ou cetamina, na dose de 25 mg/kg, com posterior avaliação das alterações comportamentais induzidas, através da avaliação da estereotipia e hiperlocomoção, depois destes ratos terem sido tratados com pregabalina (30 mg/kg ou 100 mg/kg) ou placebo. Resultados: A administração de pregabalina reduziu a hiperlocomoção nos ratos sob o efeito da cetamina. No entanto, nenhuma das doses de pregabalina teve efeito significativo sobre a estereotipia induzida pela cetamina. Conclusão:\ud
Este é o primeiro estudo que investiga os efeitos da pregabalina em um modelo animal de psicose. Nossos resultados indicam que alterações comportamentais induzidas pela cetamina em ratos podem ser revertidas após uso da pregabalina, o que sugere um possível potencial desta no tratamento de sintomas psicóticos.CNPqINCTFMRP-USPUNES
Lifetime Prevalence, Age and Gender Distribution and Age-of-Onset of Psychiatric Disorders in the Sao Paulo Metropolitan Area, Brazil: Results from the Sao Paulo Megacity Mental Health Survey

Objectives: To estimate prevalence, age-of-onset, gender distribution and identify correlates of lifetime psychiatric disorders in the Sao Paulo Metropolitan Area (SPMA). Methods: The Sao Paulo Megacity Mental Health Survey assessed psychiatric disorders on a probabilistic sample of 5,037 adult residents in the SPMA, using the World Mental Health Survey Version of the Composite International Diagnostic Interview. Response rate was 81.3%. Results: Lifetime prevalence for any disorder was 44.8%; estimated risk at age 75 was 57.7%; comorbidity was frequent. Major depression, specific phobias and alcohol abuse were the most prevalent across disorders; anxiety disorders were the most frequent class. Early age-of-onset for phobic and impulse-control disorders and later age-of-onset for mood disorders were observed. Women were more likely to have anxiety and mood disorders, whereas men, substance use disorders. Apart from conduct disorders, more frequent in men, there were no gender differences in impulse-control disorders. There was a consistent trend of higher prevalence in the youngest cohorts. Low education level was associated to substance use disorders. Conclusions: Psychiatric disorders are highly prevalent among the general adult population in the SPMA, with frequent comorbidity, early age-of-onset for most disorders, and younger cohorts presenting higher rates of morbidity. Such scenario calls for vigorous public health action.State of Sao Paulo Research Foundation (FAPESP) [03/00204-3]State of Sao Paulo Research Foundation (FAPESP)Vitoria Foundation for Science and Technology (FACITEC) [002/2003]Vitoria Foundation for Science and Technology (FACITEC)Sao Paulo State Secretaria de Seguranca Publica, through Professor Wagner Farid GattazSao Paulo State Secretaria de Seguranca Publica, through Professor Wagner Farid GattazUnited States National Institute of Mental Health [R01MH070884]United States National Institute of Mental HealthJohn D. and Catherine T. MacArthur FoundationJohn D. and Catherine T. MacArthur FoundationPfizer FoundationPfizer FoundationU.S. Public Health Service [R13-MH066849, R01-MH069864, R01 DA016558]US Public Health ServiceFogarty International CenterFogarty International Center [FIRCA R03-TW006481]Pan American Health OrganizationPan American Health OrganizationEli Lilly & Company FoundationEli Lilly & Company FoundationOrthoMcNeil Pharmaceutical, Inc.Ortho-McNeil Pharmaceutical, Inc.GlaxoSmithKlineGlaxoSmithKlineBristolMyers SquibbBristol-Myers SquibbShireShir
Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA – microRNA regulatory network in nasopharyngeal carcinoma model systems

Nasopharyngeal carcinoma (NPC) is a prevalent malignancy in Southeast Asia among the Chinese population. Aberrant regulation of transcripts has been implicated in many types of cancers including NPC. Herein, we characterized mRNA and miRNA transcriptomes by RNA sequencing (RNASeq) of NPC model systems. Matched total mRNA and small RNA of undifferentiated Epstein-Barr virus (EBV)-positive NPC xenograft X666 and its derived cell line C666, well-differentiated NPC cell line HK1, and the immortalized nasopharyngeal epithelial cell line NP460 were sequenced by Solexa technology. We found 2812 genes and 149 miRNAs (human and EBV) to be differentially expressed in NP460, HK1, C666 and X666 with RNASeq; 533 miRNA-mRNA target pairs were inversely regulated in the three NPC cell lines compared to NP460. Integrated mRNA/miRNA expression profiling and pathway analysis show extracellular matrix organization, Beta-1 integrin cell surface interactions, and the PI3K/AKT, EGFR, ErbB, and Wnt pathways were potentially deregulated in NPC. Real-time quantitative PCR was performed on selected mRNA/miRNAs in order to validate their expression. Transcript sequence variants such as short insertions and deletions (INDEL), single nucleotide variant (SNV), and isomiRs were characterized in the NPC model systems. A novel TP53 transcript variant was identified in NP460, HK1, and C666. Detection of three previously reported novel EBV-encoded BART miRNAs and their isomiRs were also observed. Meta-analysis of a model system to a clinical system aids the choice of different cell lines in NPC studies. This comprehensive characterization of mRNA and miRNA transcriptomes in NPC cell lines and the xenograft provides insights on miRNA regulation of mRNA and valuable resources on transcript variation and regulation in NPC, which are potentially useful for mechanistic and preclinical studies. © 2014 The Authors.published_or_final_versio
Temporal variability of major and trace elements concentrations in the groundwaters of Mt. Etna (Italy): effects of transient input of magmatic fluids highlighted by means of Cluster Analysis.

Data for major, minor and trace elements in groundwaters from Mt. Etna volcano collected in 1994, 1995 and 1997 were analysed using Cluster Analysis (CA). Two groups of sampling sites were identified (named clusters A and B), mainly on the basis of their different salinity and content of dissolved CO2. The highest levels of both of these parameters were observed in the sites of cluster A, located in the lower south-western and central eastern flanks of the volcano. For both of the statistical groups, CA was repeated taking into account the mean values of each parameter in time, and the results allowed us to recognize four distinct groups of parameters for each group of sites on the basis of their temporal patterns. Four different types of temporal patterns were recognised: concave, convex, increasing, decreasing. The observed changes were basically interpreted as a result of the different response of dissolved chemical elements to changes in the aqueous environment and/or in their solubility/mobility in water due to different rates of input of magmatic gases to Etna’s aquifers. The main changes occurred in 1995, when Etna’s volcanic activity resumed after a two-year period of rest. The temporal changes of the majority of the studied parameters (water temperature, water conductivity, Eh, pH, Al, Mg, B, Ca, Cl-, Hg, Mn, Mo, Na, Ni, Se, Si, Sr, Cr Zn and pCO2) were not cluster-dependent, therefore they were not apparently affected by differences in water salinity between the two groups of sampling sites. A limited number of parameters (Ti, K, Li, HCO3-, As, Fe, SO42-, Cu and V), however, showed different behaviours depending on the cluster of sites which they belonged to, thus suggesting their apparent dependency on water salinity
Natural radioactivity content in groundwater of Mt. Etna’s eastern flank and gamma background of surrounding rocks

Waters of Mt. Etna are the main source of drinking water for the local
population and are also distributed in municipal supply systems to neighbouring
areas. Radioactivity in underground waters and surrounding
rocks from the eastern flank of Mt. Etna was investigated on the basis of
9 water and 8 rock samples from 12 localities altogether. Three samples
were from water drainage galleries and six from water wells. All water intakes
are used for consumption. Activity concentration of uranium isotopes
234,238U, radium isotopes 226,228Ra and radon 222Rn were
determined with the use different nuclear spectrometry techniques. The
determination of uranium isotopes was carried out with the use of alpha
spectrometry. The measurements of radium and radon activity concentration
in water were performed with the use of a liquid scintillation technique.
Additionally, rocks surrounding the intakes were examined with
gamma spectrometry. All water samples showed uranium concentration
above Minimum Detectable Activity (MDA), with the highest total uranium
(234U + 238U) activity concentration equal to 149.2±6 mBq/L.
Conversely, all samples showed radium isotopes activity concentrations
below MDA. Radon activity concentration was within the range from
2.91±0.36 to 21.21±1.10 Bq/L, hence these waters can be classified as
low-radon waters. Gamma natural background of the rocks surrounding
the water sampling sites was found on the same levels as other volcanic
rocks of Italy
A comparison of F-region ion velocity observations from the EISCAT Svalbard and VHF radars with irregularity drift velocity measurements from the CUTLASS Finland HF radar

During August 1998, the UK EISCAT special programme SP-UK-CSUB, which combines operation of both the mainland VHF and Svalbard UHF incoherent scatter radars, was run for several hours around magnetic midnight on four consecutive days. The CUTLASS Finland HF coherent scatter radar was, at these times, operating in a discretionary mode, sounding on all 16 beams, one at high-time resolution. This study presents a comparison of the velocities measured by coherent and incoherent techniques during the SP-UK-CSUB experiments. Agreement, particularly between the ion velocities measured by the EISCAT Svalbard radar and irregularity drift measurements by the Finland radar, is remarkable, thereby validating the scientific integrity of both data sets. This work highlights the substantive contribution to our understanding of the solar-terrestrial environment which can be made by use in concert of incoherent and HF coherent scatter radars.4234
Satellite remote sensing of phytoplankton phenology in Lake Balaton using 10 years of MERIS observations

Phytoplankton biomass is important to monitor in lakes due to its influence on water quality and lake productivity. Phytoplankton has also been identified as sensitive to environmental change, with shifts in the seasonality of blooms, or phenology, resulting from changing temperature and nutrient conditions. A satellite remote sensing approach to retrieving and mapping freshwater phytoplankton phenology is demonstrated here in application to Lake Balaton, Hungary. Chlorophyll-a (chl-a) concentration mapping using Medium Resolution Imaging Spectrometer (MERIS) allows new insights into such spatiotemporal dynamics for Lake Balaton as bloom start, peak and end timing, duration, maximum chl-a concentrations, spatial extent, rates of increase and decrease, and bloom chl-a concentration integral. TIMESAT software is used to extract and map these phenology metrics. Three approaches to time series smoothing are compared and mapped metrics are evaluated in comparison with phenology metrics of in situ chl-a. The high degree of both spatial and temporal variability is highlighted and discussed, as are methodological limitations and correlation between phenology metrics. Both the feasibility of and novel insights permitted through such phenology mapping are demonstrated, and priority topics for future research are suggested.GIONET, funded by the European Commission, Marie Curie Programme Initial Training Network, Grant Agreement PITN-GA-2010-264509, NERC-funded GloboLakes project (NE/J024279/1, ESA Diversity-II project (ESRIN/AO/1-7025/12/I-LG). S. Palmer was supported by a doctoral scholarship from the Fonds de Recherche du Québec — Nature et Technologies (B2-05D-146316). H. Balzter was supported by the Royal Society Wolfson Research Merit Award, 2011/R3.Peer-reviewedPublisher Versio