pinecone/core-2020-05-10-deduplication huggingface dataset:
K -mixing in the doubly mid-shell nuclide ¹⁷⁰Dy and the role of vibrational degeneracy

A detailed study of the structure of the doubly mid-shell nucleus ¹⁷⁰₆₆Dy₁₀₄ has been carried out, following isomeric and β decay. We have measured the yrast band up to the spin-parity Jπ=6+ state, the K=2 γ -vibration band up to the 5+ state, a low-lying negative-parity band based on a 2− state that could be a candidate for the lowest energy octupole vibration state within this nucleus, and a candidate for the Kπ=6⁺ two quasi-particle isomer. This state was determined to have an excitation energy of 1643.91(23) keV and a half life of 0.99(4) μs, with a reduced hindrance for its decay to the ground-state band an order of magnitude lower than predicted by NpNn systematics. This is interpreted as being due to γ -vibrational mixing from a near degeneracy of the isomer and the 6+ state of the γ band. Furthermore, the parent nucleus ¹⁷⁰Tb has been determined to have a half-life of 0.91(ˍ₁₃⁺¹⁸)s with a possible spin-parity of 2¯.This work was partially supported by the JSPS KAKENHI
(Grant No. 25247045) and the National Research Foundation of
Korea (Grants No. NRF-2009-0093817, NRF-2013R1A1A2063017,
NRF-2014S1A2A2028636 and NRF-2015R1D1A1A01056918). OJR
acknowledges support from Science Foundation Ireland under
Grant 12/IP/1288. Work at ANL is supported by the U.S. Department
of Energy, Office of Science, Office of Nuclear Physics under
Contract No. DE-AC02-06CH11357. GL and PHR acknowledges support
from the UK National Measurements Office
Multiple TGF-β superfamily signals modulate the adult Drosophila immune response.

TGF-β superfamily signals play complex roles in regulation of tissue repair and inflammation in mammals [1]. Drosophila melanogaster is a well-established model for the study of innate immune function [2, 3] and wound healing [4–7]. Here, we explore the role and regulation of two TGF-β superfamily members, dawdle and decapentaplegic (dpp), in response to wounding and infection in adult Drosophila. We find that both TGF-β signals exhibit complex regulation in response to wounding and infection, each is expressed in a subset of phagocytes, and each inhibits a specific arm of the immune response. dpp is rapidly activated by wounds and represses the production of antimicrobial peptides; flies lacking dpp function display persistent, strong antimicrobial peptide expression after even a small wound. dawdle, in contrast, is activated by Gram-positive bacterial infection but repressed by Gram-negative infection or wounding; its role is to limit infection-induced melanization. Flies lacking dawdle function exhibit melanization even when uninfected. Together, these data imply a model in which the bone morphogenetic protein (BMP) dpp is an important inhibitor of inflammation following sterile injury whereas the activin-like dawdle determines the nature of the induced immune response
Functional characterization of novel NR5A1 variants reveals multiple complex roles in disorders of sex development

Variants in the NR5A1 gene encoding SF1 have been described in a diverse spectrum of disorders of sex development (DSD). Recently, we reported the use of a targeted gene panel for DSD where we identified 15 individuals with a variant in NR5A1, nine of which are novel. Here, we examine the functional effect of these changes in relation to the patient phenotype. All novel variants tested had reduced trans-activational activity, while several had altered protein level, localization, or conformation. In addition, we found evidence of new roles for SF1 protein domains including a region within the ligand binding domain that appears to contribute to SF1 regulation of Müllerian development. There was little correlation between the severity of the phenotype and the nature of the NR5A1 variant. We report two familial cases of NR5A1 deficiency with evidence of variable expressivity; we also report on individuals with oligogenic inheritance. Finally, we found that the nature of the NR5A1 variant does not inform patient outcomes (including pubertal androgenization and malignancy risk). This study adds nine novel pathogenic NR5A1 variants to the pool of diagnostic variants. It highlights a greater need for understanding the complexity of SF1 function and the additional factors that contribute.Gorjana Robevska, Jocelyn A. van den Bergen, Thomas Ohnesorg, Stefanie Eggers, Chloe Hanna, Remko Hersmus, Elizabeth M. Thompson, Anne Baxendale, Charles F. Verge, Antony R. Lafferty, Nanis S. Marzuki, Ardy Santosa, Nurin A. Listyasari, Stefan Riedl, Garry Warne, Leendert Looijenga, Sultana Faradz, Katie L. Ayers, Andrew H. Sinclai
Deep radio images of the HEGRA and Whipple TeV sources in the Cygnus OB2 region.

The modern generation of Cherenkov telescopes has revealed a new population of gamma-ray sources in the Galaxy. Some of them have been identified with previously known X-ray binary systems while other remain without clear counterparts a lower energies. Our initial goal here was reporting on extensive radio observations of the first extended and yet unidentified source, namely TeV J2032+4130. This object was originally detected by the HEGRA telescope in the direction of the Cygnus OB2 region and its nature has been a matter of debate during the latest years. The situation has become more complex with the Whipple and MILAGRO telescopes new TeV detections in the same field which could be consistent with the historic HEGRA source, although a different origin cannot be ruled out. Aims.We aim to pursue our radio exploration of the TeV J2032+4130 position that we initiated in a previous paper but taking now into account the latest results from new Whipple and MILAGRO TeV telescopes. The data presented here are an extended follow up of our previous work. Methods.Our investigation is mostly based on interferometric radio observations with the Giant Metre Wave Radio Telescope (GMRT) close to Pune (India) and the Very Large Array (VLA) in New Mexico (USA). We also conducted near infrared observations with the 3.5 m telescope and the OMEGA2000 camera at the Centro Astronómico Hispano Alemán (CAHA) in Almería (Spain). Results.We present deep radio maps centered on the TeV J2032+4130 position at different wavelengths. In particular, our 49 and 20 cm maps cover a field of view larger than half a degree that fully includes the Whipple position and the peak of MILAGRO emission. Our most important result here is a catalogue of 153 radio sources detected at 49 cm within the GMRT antennae primary beam with a full width half maximum (FWHM) of 43 arc-minute. Among them, peculiar sources inside the Whipple error ellipse are discussed in detail, including a likely double-double radio galaxy and a one-sided jet source of possible blazar nature. This last object adds another alternative counterpart possibility to be considered for both the HEGRA, Whipple and MILAGRO emission. Moreover, our multi-configuration VLA images reveal the non-thermal extended emission previously reported by us with improved angular resolution. Its non-thermal spectral index is also confirmed thanks to matching beam observations at the 20 and 6 cm wavelengths
Novel approaches in anti-arenaviral drug development.

Hemorrhagic fevers caused by arenaviruses are among the most devastating emerging human diseases. Considering the number of individuals affected, the current lack of a licensed vaccine, and the limited therapeutic options, arenaviruses are arguably among the most neglected tropical pathogens and the development of efficacious anti-arenaviral drugs is of high priority. Over the past years significant efforts have been undertaken to identify novel potent inhibitors of arenavirus infection. High throughput screening of small molecule libraries employing pseudotype platforms led to the discovery of several potent and broadly active inhibitors of arenavirus cell entry that are effective against the major hemorrhagic arenaviruses. Mechanistic studies revealed that these novel entry inhibitors block arenavirus membrane fusion and provided novel insights into the unusual mechanism of this process. The success of these approaches highlights the power of small molecule screens in antiviral drug discovery and establishes arenavirus membrane fusion as a robust drug target. These broad screenings have been complemented by strategies targeting cellular factors involved in productive arenavirus infection. Approaches targeting the cellular protease implicated in maturation of the fusion-active viral envelope glycoprotein identified the proteolytic processing of the arenavirus glycoprotein precursor as a novel and promising target for anti-arenaviral strategies
Concentration of Symmetric Eigenfunction

In this article we examine the concentration and oscillation effects developed by high-frequency eigenfunctions of the Laplace operator in a compact Riemannian manifold. More precisely, we are interested in the structure of the possible invariant  semiclassical measures obtained as limits of Wigner measures corresponding to eigenfunctions. These measures describe simultaneously the concentration and oscillation effects developed by a sequence of eigenfunctions. We present some results showing how to obtain invariant semiclassical measures from eigenfunctions with prescribed symmetries. As an application of these results, we give a simple proof of the fact that in a manifold of constant positive sectional curvature, every measure which is invariant by the geodesic flow is an invariant semiclassical measure
On the wess-zumino-witten anomalous functional at finite-temperature

We discuss the finite temperature extension of the anomalous Wess-Zumino-Witten lagrangian. The finite temperature S1 x S3 compactification makes a structure in disconnected sectors, corresponding to different baryon numbers appear naturally. The consistency of the anomalous functional is proved for arbitrary baryon number configurations. The anomalous behavior of the functional is shown to be consistent with the absence of finite temperature corrections to chiral anomalies in QCD, for each baryon number sector
Innovative solutions please, as long as they have been proved elsewhere:The case of a polished lime-pozzolan concrete floor

This case-study paper tells the story of the development of a bespoke lime-pozzolan concrete for an innovative project application. In this paper, the results of laboratory testing are contextualised by the project-story that steered the research programme. This is an example of a collaborative endeavour to implement a novel low-carbon construction technology in the field. Evolution of the design in parallel with laboratory testing resulted in the development and specification of a polished lime-pozzolan concrete floor incorporating site-won oolitic limestone aggregate. To the disappointment of the client and the design team, this innovative solution was abandoned at the point the contractor was appointed and changed to a proprietary polished metallic dry shake floor system. The project, a new build extension to a local authority secondary school, was completed in September 2013
Ionization in atmospheres of brown dwarfs and extrasolar planets. I. The role of electron avalanche

Brown dwarf and extrasolar planet atmospheres form clouds which strongly influence the local chemistry and physics. These clouds are globally neutral obeying dust-gas charge equilibrium which is, on short timescales, inconsistent with the observation of stochastic ionization events of the solar system planets. We argue that a significant volume of the clouds in brown dwarfs and extrasolar planets is susceptible to local discharge events. These are electron avalanches triggered by charged dust grains. Such intra-cloud discharges occur on timescales shorter than the time needed to neutralize the dust grains by collisional processes. An ensemble of discharges is likely to produce enough free charges to suggest a partial and stochastic coupling of the atmosphere to a large-scale magnetic field.Publisher PDFPeer reviewe
Testing the new CP phase in a Supersymmetric Model with Q6 Family
  Symmetry by Bs Mixing

The new contribution to the non-diagonal matrix element M_12 of the neutral
B_s meson system is investigated in a supersymmetric extension of the standard
model based on the discrete Q6 family symmetry. We assume that CP is
explicitly, but softly broken only by the b terms in the soft supersymmetry
breaking sector. We find that the new contributions to M_12 are real, and that
nevertheless there exists an observable difference in the CP phase compared
with the standard model. We focus our attention on the flavor-specific CP
asymmetry a_fs^s, and find that a_fs^s of the model is mostly negative and its
size can be one order of magnitude larger the standard model value. This
prediction is consistent with the current experimental value, and can be
experimentally tested in the near future.Comment: 10 pages, 3 figure
Evidence of triggered star formation in G327.3-0.6. Dust-continuum
  mapping of an infrared dark cloud with P-ArT\'eMiS

Aims. Expanding HII regions and propagating shocks are common in the
environment of young high-mass star-forming complexes. They can compress a
pre-existing molecular cloud and trigger the formation of dense cores. We
investigate whether these phenomena can explain the formation of high-mass
protostars within an infrared dark cloud located at the position of G327.3-0.6
in the Galactic plane, in between two large infrared bubbles and two HII
regions. Methods: The region of G327.3-0.6 was imaged at 450 ? m with the CEA
P-ArT\'eMiS bolometer array on the Atacama Pathfinder EXperiment telescope in
Chile. APEX/LABOCA and APEX-2A, and Spitzer/IRAC and MIPS archives data were
used in this study. Results: Ten massive cores were detected in the P-ArT\'eMiS
image, embedded within the infrared dark cloud seen in absorption at both 8 and
24 ?m. Their luminosities and masses indicate that they form high-mass stars.
The kinematical study of the region suggests that the infrared bubbles expand
toward the infrared dark cloud. Conclusions: Under the influence of expanding
bubbles, star formation occurs in the infrared dark areas at the border of HII
regions and infrared bubbles.Comment: 4 page
Can solvable extensions of a nilpotent subalgebra be useful in the
  classification of solvable algebras with the given nilradical?

We construct all solvable Lie algebras with a specific n-dimensional
nilradical n_{n,3} which contains the previously studied filiform nilpotent
algebra n_{n-2,1} as a subalgebra but not as an ideal. Rather surprisingly it
turns out that the classification of such solvable algebras can be reduced to
the classification of solvable algebras with the nilradical n_{n-2,1} together
with one additional case. Also the sets of invariants of coadjoint
representation of n_{n,3} and its solvable extensions are deduced from this
reduction. In several cases they have polynomial bases, i.e. the invariants of
the respective solvable algebra can be chosen to be Casimir invariants in its
enveloping algebra.Comment: 19 page
Two-loop contribution to the pion transition form factor vs.
  experimental data

We present predictions for the pion-photon transition form factor, derived
with the help of light-cone sum rules and including the main part of the NNLO
radiative corrections. We show that, when the Bakulev-Mikhailov-Stefanis (BMS)
pion distribution amplitude is used, the obtained predictions agree well with
the CELLO and the CLEO data. We found that no model distribution amplitude can
reproduce the observed $Q^2$ growth of the new BaBar data, though the BMS model
complies with several BaBar data points.Comment: 5 pages, 2 figures, 3 tables. Presented by the first author at 3rd
  joint International HADRON STRUCTURE'09 Conference at Tatranska Strba,
  Slovakia, August 30th - September 3rd, 2009. v2 Eqs. (9), (10) corrected;
  wrong reference tag removed. v3 Fig. 2 and Ref. [13] correcte
On the existence of quasipattern solutions of the Swift-Hohenberg
  equation

Quasipatterns (two-dimensional patterns that are quasiperiodic in any spatial
direction) remain one of the outstanding problems of pattern formation. As with
problems involving quasiperiodicity, there is a small divisor problem. In this
paper, we consider 8-fold, 10-fold, 12-fold, and higher order quasipattern
solutions of the Swift-Hohenberg equation. We prove that a formal solution,
given by a divergent series, may be used to build a smooth quasiperiodic
function which is an approximate solution of the pattern-forming PDE up to an
exponentially small error.Comment: 34 pages, 3 figures, submitted to Journal of Nonlinear Scienc
BTZ black hole from (3+1) gravity

We propose an approach for constructing spatial slices of (3+1) spacetimes
with cosmological constant but without a matter content, which yields (2+1)
vacuum with $\Lambda$ solutions. The reduction mechanism from (3+1) to (2+1)
gravity is supported on a criterion in which the Weyl tensor components are
required to vanish together with a dimensional reduction via an appropriate
foliation. By using an adequate reduction mechanism from the
Pleba\'nski-Carter[A] solution in (3+1) gravity, the (2+1) BTZ solution can be
obtained.Comment: 4 pages, Late
Evidence for the flavor singlet axial anomaly related effects in $\phi$
  meson electromagnetic production at large momentum transfers

The gluonic contributions to the conventional PCAC formulas due to flavor
singlet axial anomaly have been instrumental in explaining the mass of the
$\eta^{\prime}$ and providing a plausible explanation for solving the spin
crisis. We show that they also play an important role in the description of
photo- and electroproduction of vector mesons at low energy and high momentum
transfers. We calculate the contributions of this type to $\phi$ meson
electromagnetic production in a model, which contains also a soft pomeron, and
find agreement with recent CLAS data.Comment: 13 pages, 6 figures, Latex; final version to appear in Phys. Lett.
ATLAS search for new phenomena in dijet mass and angular distributions
  using pp collisions at sqrt(s)=7 TeV

Mass and angular distributions of dijets produced in LHC proton-proton
collisions at a centre-of-mass energy sqrt(s)=7 TeV have been studied with the
ATLAS detector using the full 2011 data set with an integrated luminosity of
4.8/fb. Dijet masses up to 4.0 TeV have been probed. No resonance-like features
have been observed in the dijet mass spectrum, and all angular distributions
are consistent with the predictions of QCD. Exclusion limits on six hypotheses
of new phenomena have been set at 95% CL in terms of mass or energy scale, as
appropriate. These hypotheses include excited quarks below 2.83 TeV, colour
octet scalars below 1.86 TeV, heavy W bosons below 1.68 TeV, string resonances
below 3.61 TeV, quantum black holes with six extra space-time dimensions for
quantum gravity scales below 4.11 TeV, and quark contact interactions below a
compositeness scale of 7.6 TeV in a destructive interference scenario.Comment: 29 pages plus author list (51 pages total), 8 figures, 9 tables,
  submitted to the Journal of High Energy Physics, all figures including
  auxiliary figures are available at
  http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2011-21
Resummation and S-duality in N=4 SYM

We consider the problem of resumming the perturbative expansions for
anomalous dimensions of low twist, non-BPS operators in four dimensional N=4
supersymmetric Yang-Mills theories. The requirement of S-duality invariance
imposes considerable restrictions on any such resummation. We introduce several
prescriptions that produce interpolating functions on the upper half plane that
are compatible with a subgroup of the full duality group. These lead to
predictions for the anomalous dimensions at all points in the fundamental
domain of the complex gauge coupling, and in particular at the
duality-invariant values \tau=i and \tau=exp(i\pi/3). For low-rank gauge
groups, the predictions are compatible with the bounds derived by conformal
bootstrap methods for these anomalous dimensions; within numerical errors, they
are in good agreement with the conjecture that said bounds are saturated at a
duality-invariant point. We also find that the anomalous dimensions of the
lowest twist operators lie within an extremely narrow window around a straight
line as we vary the moduli of the theory over the two dimensional fundamental
domain.Comment: 24 pages, 10 figure
MOA-2013-BLG-220Lb: Massive Planetary Companion to Galactic-Disk Host

We report the discovery of MOA-2013-BLG-220Lb, which has a super-Jupiter mass
ratio $q=3.01\pm 0.02\times 10^{-3}$ relative to its host. The proper motion,
$\mu=12.5\pm 1\, {\rm mas}\,{\rm yr}^{-1}$, is one of the highest for
microlensing planets yet discovered, implying that it will be possible to
separately resolve the host within $\sim 7$ years. Two separate lines of
evidence imply that the planet and host are in the Galactic disk. The planet
could have been detected and characterized purely with follow-up data, which
has important implications for microlensing surveys, both current and into the
LSST era.Comment: 2 tables, 2 figure
Complete Graphs, Hilbert Series, and the Higgs branch of the 4d N=2
  $(A_n,A_m)$ SCFT's

The strongly interacting 4d N=2 SCFT's of type $(A_n,A_m)$ are the simplest
examples of models in the $(G,G^\prime)$ class introduced by Cecotti, Neitzke,
and Vafa in arXiv:1006.3435. These systems have a known 3d N=4 mirror only if
$h(A_n)$ divides $h(A_m)$, where $h$ is the Coxeter number. By 4d/2d
correspondence, we show that in this case these systems have a nontrivial
global flavor symmetry group and, therefore, a non-trivial Higgs branch. As an
application of the methods of arXiv:1309.2657, we then compute the refined
Hilbert series of the Coulomb branch of the 3d mirror for the simplest models
in the series. This equals the refined Hilbert series of the Higgs branch of
the $(A_n,A_m)$ SCFT, providing interesting information about the Higgs branch
of these non-lagrangian theories.Comment: 20 page
Modelling and analysis of turbulent datasets using ARMA processes

We introduce a novel way to extract information from turbulent datasets by
applying an ARMA statistical analysis. Such analysis goes well beyond the
analysis of the mean flow and of the fluctuations and links the behavior of the
recorded time series to a discrete version of a stochastic differential
equation which is able to describe the correlation structure in the dataset. We
introduce a new intermittency parameter $\Upsilon$ that measures the difference
between the resulting analysis and the Obukhov model of turbulence, the
simplest stochastic model reproducing both Richardson law and the Kolmogorov
spectrum. We test the method on datasets measured in a von K\'arm\'an swirling
flow experiment. We found that the ARMA analysis is well correlated with
spatial structures of the flow, and can discriminate between two different
flows with comparable mean velocities, obtained by changing the forcing.
Moreover, we show that the intermittency parameter is highest in regions where
shear layer vortices are present, thereby establishing a link between
intermittency corrections and coherent structures. We show that some salient
features of the analysis are preserved when considering global instead of local
observables. Finally we analyze flow configurations with multistability
features where the ARMA technique is efficient in discriminating different
stability branches of the system.Comment: 33 pages, 8 figure