pinecone/core-2020-05-10-deduplication huggingface dataset:
Climate change and river flooding: part 1 classifying the sensitivity of British catchments

The final publication is available at Springer via http://dx.doi.org/10.1007/s10584-013-0748-xEffective national and regional policy guidance on climate change adaptation relies on robust scientific evidence. This two-part series of papers develops and implements a novel scenario-neutral framework enabling an assessment of the vulnerability of flood flows in British catchments to climatic change, to underpin the development of guidance for the flood management community. In this first part, the sensitivity of the 20-year return period flood peak (RP20) to changes in precipitation (P), temperature (T) and potential evapotranspiration (PE) is systematically assessed for 154 catchments. A sensitivity domain of 4,200 scenarios is applied combining 525 and 8 sets of P and T/PE mean monthly changes, respectively, with seasonality incorporated using a single-phase harmonic function. Using the change factor method, the percentage change in RP20 associated with each scenario of the sensitivity domain is calculated, giving flood response surfaces for each catchment. Using a clustering procedure on the response surfaces, the 154 catchments are divided into nine groups: flood sensitivity types. These sensitivity types show that some catchments are (very) sensitive to changes in P but others buffer the response, while the location of catchments of the same type does not show any strong geographical pattern. These results reflect the range of hydrological processes found in Britain, and demonstrate the potential importance of catchment properties (physical and climatic) in the propagation of change in climate to change in floods, and so in characterising the sensitivity types (covered in the companion paper)
Socially Impaired Robots: Human Social Disorders and Robots'
  Socio-Emotional Intelligence

Social robots need intelligence in order to safely coexist and interact with
humans. Robots without functional abilities in understanding others and unable
to empathise might be a societal risk and they may lead to a society of
socially impaired robots. In this work we provide a survey of three relevant
human social disorders, namely autism, psychopathy and schizophrenia, as a
means to gain a better understanding of social robots' future capability
requirements. We provide evidence supporting the idea that social robots will
require a combination of emotional intelligence and social intelligence, namely
socio-emotional intelligence. We argue that a robot with a simple
socio-emotional process requires a simulation-driven model of intelligence.
Finally, we provide some critical guidelines for designing future
socio-emotional robots.Comment: International Conference on Social Robotics 201
On the universality of thermodynamics and $\eta/s$ ratio for the charged
  Lovelock black branes

We investigate general features of charged Lovelock black branes by giving a
detailed description of geometrical, thermodynamic and holographic properties
of charged Gauss-Bonnet (GB) black branes in five dimensions. We show that when
expressed in terms of effective physical parameters, the thermodynamic
behaviour of charged GB black branes is completely indistinguishable from that
of charged Einstein black branes. Moreover, the extremal, near-horizon limit of
the two classes of branes is exactly the same as they allow for the same
AdS$_2\times R_3$, near-horizon, exact solution. This implies that, although in
the UV the associated dual QFTs are different, they flow in the IR to the same
fixed point. The calculation of the shear viscosity to entropy ratio $\eta/s$
confirms these results. Despite the GB dual plasma has in general a
non-universal temperature-dependent $\eta/s$, it flows monotonically to the
universal value $1/4\pi$ in the IR. For negative (positive) GB coupling
constant, $\eta/s$ is an increasing (decreasing) function of the temperature
and the flow respects (violates) the KSS bound.Comment: 28 pages, 3 figures, some references adde
MSSM-like from $SU_{5}\times D_{4}$ Models

Using finite discrete group characters and symmetry breaking by hyperflux as
well as constraints on top- quark family, we study minimal low energy effective
theory following from SU$_{5}\times D_{4}$ models embedded in F-theory with non
abelian flux. Matter curves spectrum of the models is obtained from
SU$_{5}\times S_{5}$ theory with monodromy $S_{5}$ by performing two breakings;
first from symmetric group $S_{5}$ to $S_{4}$ subsymmetry; and next to dihedral
$D_{4}$ subgroup. As a consequence, and depending on the ways of decomposing
triplets of $S_{4}$, we end with three types of $D_{4}$- models. Explicit
constructions of these theories are given and a MSSM- like spectrum is derived.Comment: 48 pages, LaTe
K2-110 b - a massive mini-Neptune exoplanet

We report the discovery of the exoplanet K2-110 b (previously EPIC212521166b)
from K2 photometry orbiting in a 13.8637d period around an old, metal-poor K3
dwarf star. With a V-band magnitude of 11.9, K2-110 is particularly amenable to
RV follow-up. A joint analysis of K2 photometry and high-precision RVs from 28
HARPS and HARPS-N spectra reveal it to have a radius of 2.6$\pm 0.1 R_{\oplus}$
and a mass of 16.7$\pm 3.2$~M$_{\oplus}$, hence a density of $5.2\pm1.2$
g.cm$^{-3}$, making it one of the most massive planets yet to be found with a
sub-Neptune radius. When accounting for compression, the resulting Earth-like
density is best fitted by a 0.2 M$_{\oplus}$ hydrogen atmosphere over an 16.5
M$_{\oplus}$ Earth-like interior, although the planet could also have
significant water content. At 0.1~AU, even taking into account the old stellar
age of $8 \pm 3$ Gyr, the planet is unlikely to have been significantly
affected by EUV evaporation. However the planet likely disc-migrated to its
current position making the lack of a thick H$_2$ atmosphere puzzling. This
analysis has made K2-110 b one of the best-characterised mini-Neptunes with
density constrained to less than 30%.Comment: Submitted to A&A, May 2016; Accepted April 201
Reconciling Planck with the local value of $H_0$ in extended parameter
  space

The recent determination of the local value of the Hubble constant by Riess
et al, 2016 (hereafter R16) is now 3.3 sigma higher than the value derived from
the most recent CMB anisotropy data provided by the Planck satellite in a LCDM
model. Here we perform a combined analysis of the Planck and R16 results in an
extended parameter space, varying simultaneously 12 cosmological parameters
instead of the usual 6. We find that a phantom-like dark energy component, with
effective equation of state $w=-1.29_{-0.12}^{+0.15}$ at 68 % c.l. can solve
the current tension between the Planck dataset and the R16 prior in an extended
$\Lambda$CDM scenario. On the other hand, the neutrino effective number is
fully compatible with standard expectations. This result is confirmed when
including cosmic shear data from the CFHTLenS survey and CMB lensing
constraints from Planck. However, when BAO measurements are included we find
that some of the tension with R16 remains, as also is the case when we include
the supernova type Ia luminosity distances from the JLA catalog.Comment: 6 pages, 1 figur
Petrographic features as an effective indicator for the variation in strength of granites

AcceptedArticlethis is the author’s version of a work that was accepted for publication in Engineering Geology.  A definitive version was subsequently published in Engineering Geology, http://dx.doi.org/10.1016/j.enggeo.2016.01.001The textural characteristics of four different granites from the lower Himalayan regime in north-western Pakistan have been examined in relation to their effect on the mechanical nature of rock. Detailed petrographic examination and subsequent quantitative QEMSCAN analysis provide better understanding of the difference between their textures. Three of the granite types are slightly altered (Grade-II) whereas the other has a higher degree of alteration and corresponds to alteration Grade-III. The mechanical properties determined for each granite type include: unconfined compressive and tensile strength, elastic modulus, P-wave velocity, Schmidt hardness and dry density. Statistical analyses, combined with post-test petrography, demonstrate textural control on mechanical properties. The important petrographic characteristics influencing mechanical behaviour include modal concentration and grain size of individual minerals, mean grain size of rock and distribution of grain size within a rock. Recrystallization of minerals along boundaries has a pronounced effect on increased strength of granites. Texture, however, has a significant influence on the variation of strength of granites with similar alteration grade.Commonwealth Scholarship Commission, U
Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs)

Somatic mutations in the promoter region of telomerase reverse transcriptase (TERT) gene, mainly at positions c.-124 and c.-146 bp, are frequent in several human cancers; yet its presence in gastrointestinal stromal tumor (GIST) has not been reported to date. Herein, we searched for the presence and clinicopathological association of TERT promoter mutations in genomic DNA from 130 bona fide GISTs. We found TERT promoter mutations in 3.8% (5/130) of GISTs. The c.-124C>T mutation was the most common event, present in 2.3% (3/130), and the c.-146C>T mutation in 1.5% (2/130) of GISTs. No significant association was observed between TERT promoter mutation and patient's clinicopathological features. The present study establishes the low frequency (4%) of TERT promoter mutations in GISTs. Further studies are required to confirm our findings and to elucidate the hypothetical biological and clinical impact of TERT promoter mutation in GIST pathogenesis.This project was partially supported by Barretos Cancer Hospital internal research funds (PAIP) and CNPq Universal Grant (476192/2013-7) to RMR. NCC is a recipient of an FAPESP Doctoral Fellowship (2013/25787-3). Further funding from the project ‘Microenvironment, metabolism and cancer’ that was partially supported by Programa Operacional Regional do Norte (ON.2—O Novo Norte) under the Quadro de Referência Estratégico Nacional (QREN) and the Fundo Europeu de Desenvolvimento Regional (FEDER). IPATIMUP is an Associate Laboratory of the Portuguese Ministry of Science, Technology and Higher Education that is partially supported by the FCT
Elasticity of (K,Na)AlSi3O8 hollandite from lattice dynamics calculations

International audienceWe compute the elastic constants tensor and the seismic properties of KAlSiO and KNaAlSiO up to the ferroelastic transition using density-functional theory and density-functional perturbation theory in the ABINIT implementation. We observe a softening of the tetragonal shear with pressure that precedes the ferroelastic transition. The Reuss shear moduli become negative at respectively 23GPa and 13GPa for the two compositions considered in here. The ferroelastic transition is associated with a strong decrease of the horizontal shear wave velocities and a corresponding increase of the seismic anisotropy. The presence of Na enhances these features
Evidence for 9 planets in the HD 10180 system

We re-analyse the HARPS radial velocities of HD 10180 and calculate the
probabilities of models with differing numbers of periodic signals in the data.
We test the significance of the seven signals, corresponding to seven
exoplanets orbiting the star, in the Bayesian framework and perform comparisons
of models with up to nine periodicities. We use posterior samplings and
Bayesian model probabilities in our analyses together with suitable prior
probability densities and prior model probabilities to extract all the
significant signals from the data and to receive reliable uncertainties for the
orbital parameters of the six, possibly seven, known exoplanets in the system.
According to our results, there is evidence for up to nine planets orbiting HD
10180, which would make this this star a record holder in having more planets
in its orbits than there are in the Solar system. We revise the uncertainties
of the previously reported six planets in the system, verify the existence of
the seventh signal, and announce the detection of two additional statistically
significant signals in the data. If of planetary origin, these two additional
signals would correspond to planets with minimum masses of 5.1$^{+3.1}_{-3.2}$
and 1.9$^{+1.6}_{-1.8}$ M$_{\oplus}$ on orbits with 67.55$^{+0.68}_{-0.88}$ and
9.655$^{+0.022}_{-0.072}$ days periods (denoted using the 99% credibility
intervals), respectively.Comment: 12 pages, 7 figures, accepted for publication in the Astronomy and
  Astrophysic
Dynamical semigroup for unbounded repeated perturbation of an open system

International audienceWe consider dynamical semigroups with unbounded Kossakowski-Lindblad-Davies generators which are related to evolution of an open system with a tuned repeated harmonic perturbation. Our main result is the proof of existence of uniquely determined minimal trace-preserving strongly continuous dynamical semigroups on the space of density matrices. The corresponding dual W *-dynamical system is shown to be unital quasi-free and completely positive automorphisms of the CCR-algebra. We also comment on the action of dynamical semigroups on quasi-free states
Quinolinate synthase, an iron-sulfur enzyme in NAD biosynthesis

International audienceNicotinamide adenine dinucleotide (NAD) plays a crucial role as a cofactor in numerous essential redox biological reactions. NAD derives from quinolinic acid which is synthesized in E. coli from L-aspartate and dihydroxyacetone phosphate (DHAP) as the result of the concerted action of two enzymes, L-aspartate oxidase (NadB) and quinolinate synthetase (NadA). We report here the characterization of NadA protein from E. coli. When anaerobically purified, the isolated soluble protein contains 3-3.5 iron and 3-3.5 sulfide/ polypeptide chain. Mössbauer spectra of the 57Fe-protein revealed that the majority of the iron is in the form of a (4Fe-4S)2+ cluster. An enzymatic assay for quinolinate synthetase activity was set up and allowed to demonstrate that the cluster is absolutely required for NadA activity. Exposure to air leads to degradation of the cluster and inactivate enzyme
Planck intermediate results

International audienceWe present an analysis of Planck satellite data on the Coma cluster observed via the Sunyaev-Zeldovich effect. Thanks to its great sensitivity, Planck is able, for the first time, to detect SZ emission up to r ≈ 3 × R500. We test previously proposed spherically symmetric models for the pressure distribution in clusters against the azimuthally averaged data. In particular, we find that the Arnaud et al. (2010, A&A, 517, A92) “universal” pressure profile does not fit Coma, and that their pressure profile for merging systems provides a reasonable fit to the data only at r < R500; by r = 2 × R500 it underestimates the observed y profile by a factor of ≃2. This may indicate that at these larger radii either: i) the cluster SZ emission is contaminated by unresolved SZ sources along the line of sight; or ii) the pressure profile of Coma is higher at r > R500 than the mean pressure profile predicted by the simulations used to constrain the models. The Planck image shows significant local steepening of the y profile in two regions about half a degree to the west and to the south-east of the cluster centre. These features are consistent with the presence of shock fronts at these radii, and indeed the western feature was previously noticed in the ROSAT PSPC mosaic as well as in the radio. Using Plancky profiles extracted from corresponding sectors we find pressure jumps of 4.9-0.2+0.4 and 5.0-0.1+1.3 in the west and south-east, respectively. Assuming Rankine-Hugoniot pressure jump conditions, we deduce that the shock waves should propagate with Mach number Mw = 2.03-0.04+0.09 and Mse = 2.05-0.02+0.25 in the west and south-east, respectively. Finally, we find that the y and radio-synchrotron signals are quasi-linearly correlated on Mpc scales, with small intrinsic scatter. This implies either that the energy density of cosmic-ray electrons is relatively constant throughout the cluster, or that the magnetic fields fall off much more slowly with radius than previously thought
Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV-1 Tat protein antagonists.

The HIV-1 transactivating factor (Tat) acts as an extracellular cytokine on target cells, including endothelium. Here, we report about the Tat-antagonist capacity of chemically sulfated derivatives of the Escherichia coli K5 polysaccharide. O-sulfated K5 with high sulfation degree (K5-OS(H)) and N,O-sulfated K5 with high (K5-N,OS(H)) or low (K5-N,OS(L)) sulfation degree, but not unmodified K5, N-sulfated K5, and O-sulfated K5 with low sulfation degree, bind to Tat preventing its interaction with cell surface heparan sulfate proteoglycans, cell internalization, and consequent HIV-LTR-transactivation. Also, K5-OS(H) and K5-N,OS(H) prevent the interaction of Tat to the vascular endothelial growth factor receptor-2 on endothelial cell (EC) surface. Finally, K5-OS(H) inhibits alphav beta3 integrin/Tat interaction and EC adhesion to immobilized Tat. Consequently, K5-OS(H) and K5-N,OS(H) inhibit the angiogenic activity of Tat in vivo. In conclusion, K5 derivatives with distinct sulfation patterns bind extracellular Tat and modulate its interaction with cell surface receptors and affect its biological activities. These findings provide the basis for the design of novel extracellular Tat antagonists with possible implications in anti-AIDS therapies
J− factors of short DNA molecules

The propensity of short DNA sequences to convert to the circular form is studied by a mesoscopic Hamiltonian method which incorporates both the bending of the molecule axis and the intrinsic twist of the DNA strands. The base pair fluctuations with respect to the helix diameter are treated as path trajectories in the imaginary time path integral formalism. The partition function for the sub-ensemble of closed molecules is computed by imposing chain end boundary conditions both on the radial fluctuations and on the angular degrees of freedom. The cyclization probability, the J-factor, proves to be highly sensitive to the stacking potential, mostly to its nonlinear parameters. We find that the J-factor generally decreases by reducing the sequence length (N) and, more significantly, below N = 100 base pairs. However, even for very small molecules, the J-factors remain sizeable in line with recent experimental indications. Large bending angles between adjacent base pairs and anharmonic stacking appear as the causes of the helix flexibility at short length scales
Sensitive and specificity of different measures of adiposity to distinguish between low/high motor coordination

Available online 7 September 2014; Article in pressObjective
This study aimed to determine the ability of different measures of adiposity to discriminate between low/high motor coordination and to evaluate the relationship between different measures of adiposity and motor coordination.

Methods
This study included 596 elementary school children aged 9 to 12 years (218 females – 47.1%). Weight, height, and waist circumference were objectively measured by standardized protocols. Body fat percentage was estimated by bioelectric impedance. Body mass index and waist-to-height ratio were computed. Motor coordination was assessed by the Körperkoordination Test für Kinder. Cardiorespiratory fitness was predicted by a maximal multistage 20 m shuttle-run test of the Fitnessgram Test Battery. A questionnaire was used to assess the maternal educational level.

Results
The receiver operating characteristic performance of body fat percentage in females and waist circumference in males presented a slightly better discriminatory accuracy than body mass index, waist circumference and waist-to-height ratio in predicting low motor coordination. After adjustments, logistic regression analyses showed that body mass index (β = 2.155; 95% CI: 1.164-3.992; p = 0.015 for girls; β = 3.255; 95% CI: 1.740-6.088; p < 0.001 for males), waist circumference (β = 2.489; 95% CI: 1.242-4.988; p = 0.010 for girls; β = 3.296; 95% CI: 1.784-6.090; p < 0.001 for males), body fat percentage (β = 2.395; 95% CI: 1.234-4.646; p = 0.010 for girls; β = 2.603; 95% CI: 1.462-4.634; p < 0.001 for males) and waist-to-height ratio (β = 3.840; 95% CI: 2.025-7.283; p < 0.001 for males) were positively and significantly associated with motor coordination in both sexes, with the exception of waist-to-height ratio in girls (β = 1.343; 95% CI: 0.713-2.528; p = 0.381).

Conclusion
Body fat percentage and waist circumference showed a slightly better discriminatory accuracy in predicting low motor coordination for females and for males, respectively.CIEC – Research Centre on Child Studies, UM (FCT R&D 317
Fiducial and differential cross sections of Higgs boson production measured in the four-lepton decay channel in pp collisions at s√=8 TeV with the ATLAS detector

Measurements of fiducial and differential cross sections of Higgs boson production in the H → Z Z∗ → 4
decay channel are presented. The cross sections are determined within a fiducial phase space and
corrected for detection efficiency and resolution effects. They are based on 20.3 fb−1 of pp collision
data, produced at √s = 8 TeV centre-of-mass energy at the LHC and recorded by the ATLAS detector.
The differential measurements are performed in bins of transverse momentum and rapidity of the fourlepton
system, the invariant mass of the subleading lepton pair and the decay angle of the leading lepton
pair with respect to the beam line in the four-lepton rest frame, as well as the number of jets and
the transverse momentum of the leading jet. The measured cross sections are compared to selected
theoretical calculations of the Standard Model expectations. No significant deviation from any of the
tested predictions is found.We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COL-CIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America