pinecone/core-2020-05-10-deduplication huggingface dataset:
Surface magnetism in ZnO/Co3O4 mixtures

5 pages, 7 figures.We recently reported the observation of room temperature ferromagnetism in mixtures of ZnO and Co3O4 despite the diamagnetic and antiferromagnetic character of these oxides, respectively. Here, we present a detailed study on the electronic structure of this material in order to account for the unexpected ferromagnetism. Electrostatic interactions between both oxides lead to a dispersion of Co3O4 particles over the surface of ZnO larger ones. As a consequence, the reduction Co+3→Co2+ at the particle surface takes place as evidenced by x-ray absorption spectroscopy measurements and optical spectroscopy. This reduction allows explaining the observed ferromagnetic signal within the well established theories of magnetism in oxides.This work was supported by the Spanish\ud
Council for Scientific Research through Project Nos. CSIC\ud
2006-50F0122 and CSIC 2007-50I015 and Spanish Ministry\ud
of Science and Education through Project Nos. MAT2007-\ud
66845-C02-01 and FIS-2008-06249.Peer reviewe
FCNC and CP violation observables in an SU(3)-flavoured MSSM

A non-Abelian flavour symmetry in a minimal supersymmetric standard model can explain the flavour structures in the Yukawa couplings and simultaneously solve the SUSY flavour problem. Similarly the SUSY CP problem can be solved if CP is spontaneously broken in the flavour sector. In this work, we present an explicit example of these statements with an SU(3) flavour symmetry and spontaneous CP violation. In addition, we show that it is still possible to find some significant deviation from the SM expectations as far as FCNC and CP violation are concerned. We find that large contributions can be expected in lepton flavour violating decays, as mu >-> e gamma and tau -> mu gamma, electric dipole moments, d(e) and d(n) and kaon CP violating processes as is an element of(K). We also show that without further modifications, it is unlikely for these models to solve the Phi(Bs) anomaly at low-moderate tan beta. Thus, these flavoured MSSM realizations are phenomenologically sensitive to the experimental searches in the realm of flavor and CP violation physics.We would like to thank G. G. Ross, I. de Medeiros Varzielas and M. Passera for useful discussions.\ud
L. C. wishes to thank the University of Valencia for the kind hospitality and partial support\ud
during various stages of this work. J. J. P. thanks the universities of Padova and Würzburg for\ud
hospitality during his visits to complete this work. A. M., J.-h. P. and O. V. would like to thank the\ud
Yukawa Institute, Kyoto and the research project YKIS for providing the opportunity to develop\ud
an important part of this work in a stimulating and active environment. We acknowledge support\ud
from the MEC-INFN agreements FPA2008-04065-E and INFN2008-016. The work of O. V. and\ud
J. J. P. was supported by the Spanish MICINN and FEDER (EC) Grant No. FPA2008-02878.\ud
O. V. was supported in part by European program MRTN-CT-2006-035482 “Flavianet” and the\ud
Generalitat Valenciana under the grant PROMETEO/2008/004. A. M. acknowledges partial support\ud
from the CARIPARO Project of Excellence (LHCosmology). W. P. is partially supported by\ud
the German Ministry of Education and Research (BMBF) under contract 05HT6WWA. J.-h. P. acknowledges\ud
Research Grants funded jointly by the Italian Ministero dell’Istruzione, dell’Università\ud
e della Ricerca (MIUR), by the University of Padova and by INFN within the Astroparticle Physics\ud
Project. A. M. and W. P. are partially supported by MRTN-CT-2006-035505 (Hep-Tools). A. M. and J.-h. P. acknowledge partial support from the INFN FA51 Grant and from the RTN European\ud
Contracts MRTN-CT-2006-035863 (UniverseNet).Peer reviewe
A novel protein motif finding algorithm for classification of the ligase subfamilies

The algorithm of extracting motifs from a family or subfamily is still a hot spot in bioinformatics. It not only contributes to understand functions of proteins and predicts the classification which a unknown protein sequence belongs to, but also helps to study the protein-protein interaction. In this paper, we present a novel algorithm to extract motifs of a subfamily, which is based on feature selection and position connection. Position connection is applied to generate motifs, which is the hybrid method with mechanism of vote decision-making to construct the classifier of the ligase subfamilies. Through testing in the database, more than 95.87% predictive accuracy is achieved. The result demonstrates that this novel method is practical. In addition, the method illuminates that motifs play an important role to classify proteins and research the characteristics of the subfamilies or families of protein database.PRIB 2008 proceedings found at: http://dx.doi.org/10.1007/978-3-540-88436-
Developing clinical scenarios from a European perspective: Successes and challenges

This paper presents developmental work involving students from the University College Dublin (UCD), Ireland (n = 9), University of Surrey, England (n = 8) and University of Ljubljana and University of Maribor, Slovenia (n = 5) participating in the Erasmus Intensive Programme. The Erasmus programme offers a two week 'Summer School' in the Faculty of Health Sciences, University of Maribor, Slovenia. Using a participatory approach, facilitators from both the UCD and Surrey engaged with students from all of the universities to develop scenarios for simulated learning experiences, in the care of older people, for utilisation on an e learning facility and within the simulated clinical learning environment. Students developed key transferable skills in learning, such as information literacy, cultural diversity, team working, communication, and clinical skills acquisition whilst exploring differences in healthcare delivery in other European countries. © 2011 Elsevier Ltd
"Brick-topia", the thin-tile vaulted pavilion

The project ‘‘Brick-topia’’ was based on a combination of the latest structural analysis and form-finding computational tools with traditional, cheap and effective construction techniques.\ud
It is the result of innovation to fight against budget and time. The initial budget was 3000 euros and only seven weeks was the time to look for sponsors, design the pavilion, plan the construction phases and build it.\ud
The whole process of designing, decision on the materials, structural analysis and construction is presented in the paper, including exploration on new form-finding methods to redesign a project in situ and research on a new formwork system using scaffolding, cardboard, wire and steel rods and having a cutter as main toolPostprint (published version
Pedagogy, empowerment and discipline: comparative perspectives of novice teachers in England and Turkey reflecting on ‘the other’

This paper discusses the views of Turkish and British novice teachers on pedagogy\ud
and pedagogical relationships with school students when confronted with the\ud
pedagogical practices of the ‘Other’. Experiences of those practices were gained by\ud
novice teachers during an exchange visit for British and Turkish university\ud
students in 2008-2009. Data was collected through questionnaires and focus group\ud
interviews. Findings suggest that Turkish and British novice teachers initially\ud
constructed the ‘Other’ as very different from themselves. The views of members\ud
of both groups were heavily influenced by the cultural contexts in which they\ud
trained and worked. British novice teachers tended to take as axiomatic\ud
constructivist approaches to pedagogy and the relevance to successful pedagogy of\ud
listening to students’ voices. Turkish novice teachers questioned both, many seeing\ud
control and dissemination of knowledge as central to pedagogy and student teacher\ud
relationships.Peer-reviewedPost-prin
Energy-efficient checkpointing in high-throughput cycle-stealing distributed systems.

Checkpointing is a fault-tolerance mechanism commonly used in High Throughput Computing (HTC) environments to allow the execution of long-running computational tasks on compute resources subject to hardware or software failures as well as interruptions from resource owners and more important tasks. Until recently many researchers have focused on the performance gains achieved through checkpointing, but now with growing scrutiny of the energy consumption of IT infrastructures it is increasingly important to understand the energy impact of checkpointing within an HTC environment. In this paper we demonstrate through trace-driven simulation of real-world datasets that existing checkpointing strategies are inadequate at maintaining an acceptable level of energy consumption whilst maintaing the performance gains expected with checkpointing. Furthermore, we identify factors important in deciding whether to exploit checkpointing within an HTC environment, and propose novel strategies to curtail the energy consumption of checkpointing approaches whist maintaining the performance benefits
Experiences of hearing voices : analysis of a novel phenomenological survey.

Background: Auditory hallucinations—or voices—are a common feature of many psychiatric disorders and are also experienced by individuals with no psychiatric history. Understanding of the variation in subjective experiences of hallucination is central to psychiatry, yet systematic empirical research on the phenomenology of auditory hallucinations remains scarce. We aimed to record a detailed and diverse collection of experiences, in the words of the people who hear voices themselves.\ud
\ud
Methods: We made a 13 item questionnaire available online for 3 months. To elicit phenomenologically rich data, we designed a combination of open-ended and closed-ended questions, which drew on service-user perspectives and approaches from phenomenological psychiatry, psychology, and medical humanities. We invited people aged 16–84 years with experience of voice-hearing to take part via an advertisement circulated through clinical networks, hearing voices groups, and other mental health forums. We combined qualitative and quantitative methods, and used inductive thematic analysis to code the data and χ2 tests to test additional associations of selected codes.\ud
\ud
Findings: Between Sept 9 and Nov 29, 2013, 153 participants completed the study. Most participants described hearing multiple voices (124 [81%] of 153 individuals) with characterful qualities (106 [69%] individuals). Less than half of the participants reported hearing literally auditory voices—70 (46%) individuals reported either thought-like or mixed experiences. 101 (66%) participants reported bodily sensations while they heard voices, and these sensations were significantly associated with experiences of abusive or violent voices (p=0·024). Although fear, anxiety, depression, and stress were often associated with voices, 48 (31%) participants reported positive emotions and 49 (32%) reported neutral emotions. Our statistical analysis showed that mixed voices were more likely to have changed over time (p=0·030), be internally located (p=0·010), and be conversational in nature (p=0·010).\ud
\ud
Interpretation: This study is, to our knowledge, the largest mixed-methods investigation of auditory hallucination phenomenology so far. Our survey was completed by a diverse sample of people who hear voices with various diagnoses and clinical histories. Our findings both overlap with past large-sample investigations of auditory hallucination and suggest potentially important new findings about the association between acoustic perception and thought, somatic and multisensorial features of auditory hallucinations, and the link between auditory hallucinations and characterological entities
'Like sugar and honey' : the embedded ethics of a larval control project in The Gambia.

This paper describes a malaria research project in The Gambia to provoke thinking on the social value of transnational research. The Larval Control Project (LCP) investigated the efficacy of a microbial insecticide to reduce vector density and, ultimately, clinical malaria in Gambian children. The LCP’s protocol delineated a clinical surveillance scheme that involved Village Health Workers (VHWs) supported by project nurses. Combining insights from ethnographic fieldwork conducted at the Medical Research Council (MRC) Laboratories in Farafenni from 2005 to 2009, open-ended interviews with project nurses, and eight focus group discussions held with participant mothers in October 2007, we consider the social impact of the LCP’s investigative method against the backdrop of several years of research activity. We found that while participants associated the LCP with the clinical care it provided, they also regarded the collaboration between the nurses and VHWs added additional benefits. Organised around the operational functions of the trial, small-scale collaborations provided the platform from which to build local capacity. While ethical guidelines emphasise the considerations that must be added to experimental endeavour in southern countries (e.g. elaborating processes of informed consent, developing strategies of community engagement or providing therapeutic access to participants after the trial concludes), these findings suggest that shifting attention from supplementing ethical protocols to the everyday work of research – embedding ethics through scientific activity – may provide a sounder basis to reinforce the relationship between scientific rigour and social value
Search for the Standard Model Higgs boson produced by vector-boson
  fusion in 8 TeV $pp$ collisions and decaying to bottom quarks with the ATLAS
  detector

A search with the ATLAS detector is presented for the Standard Model Higgs
boson produced by vector-boson fusion and decaying to a pair of bottom quarks,
using 20.2 ${fb}^{-1}$ of LHC proton-proton collision data at $\sqrt{s}$ = 8
TeV. The signal is searched for as a resonance in the invariant mass
distribution of a pair of jets containing $b$-hadrons in vector-boson-fusion
candidate events. The yield is measured to be $-0.8 \pm 2.3$ times the Standard
Model cross-section for a Higgs boson mass of 125 GeV. The upper limit on the
cross-section times the branching ratio is found to be 4.4 times the Standard
Model cross-section at the 95% confidence level, consistent with the expected
limit value of 5.4 (5.7) in the background-only (Standard Model production)
hypothesis.Comment: 19 pages plus author list (36 pages total), 7 figures, 4 tables,
  published version, all figures including auxiliary figures are available at
  https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HIGG-2014-12
Discovery of "isolated" co-moving T Tauri stars in Cepheus

Context. During the course of a large spectroscopic survey of X-ray active late-type stars in the solar neighbourhood, we discovered four lithium-rich stars packed within just a few degrees on the sky. Although located in a sky area rich in CO molecular regions and dark clouds, the Cepheus-Cassiopeia complex, these very young stars are projected several degrees away from clouds in front of an area void of interstellar matter. As such, they are very good "isolated" T Tauri star candidates. Aims. We present optical observations of these stars conducted with 1-2 m class telescopes. We acquired high-resolution optical spectra as well as photometric data allowing us to investigate in detail their nature and physical parameters with the aim of testing the "runaway" and "in-situ" formation scenarios. Their kinematical properties are also analyzed to investigate their possible connection to already known stellar kinematic groups. Methods. We use the cross-correlation technique and other tools developed by us to derive accurate radial and rotational velocities and perform an automatic spectral classification. The spectral subtraction technique is used to infer chromospheric activity level in the Hα line core and clean the spectra of photospheric lines before measuring the equivalent width of the lithium absorption line. Results. Both physical (lithium content, chromospheric, and coronal activities) and kinematical indicators show that all stars are very young, with ages probably in the range 10-30 Myr. In particular, the spectral energy distribution of TYC4496-780-1 displays a strong near-and far-infrared excess, typical of T Tauri stars still surrounded by an accretion disc. They also share the same Galactic motion, proving that they form a homogeneous moving group of stars with the same origin. Conclusions. The most plausible explanation of how these "isolated" T Tauri stars formed is the "in-situ" model, although accurate distances are needed to clarify their connection with the Cepheus-Cassiopeia complex. The discovery of this loose association of "isolated" T Tauri stars can help to shed light on atypical formation processes of stars and planets in low-mass clouds
A large genome-wide association study of age-related macular degeneration highlights contribution of rare and common variants

Author manuscript version (post print) made available following 6 month embargo from date of publication (21 December 2015) in accordance with publisher copyright policy.Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, mostly rare, protein-altering variants. Analyzing 16,144 patients and 17,832 controls, we identify 52 independently associated common and rare variants (P < 5 × 10(-8)) distributed across 34 loci. Although wet and dry AMD subtypes exhibit predominantly shared genetics, we identify the first genetic association signal specific to wet AMD, near MMP9 (difference P value = 4.1 × 10(-10)). Very rare coding variants (frequency <0.1%) in CFH, CFI and TIMP3 suggest causal roles for these genes, as does a splice variant in SLC16A8. Our results support the hypothesis that rare coding variants can pinpoint causal genes within known genetic loci and illustrate that applying the approach systematically to detect new loci requires extremely large sample sizes
Searches for light- and heavy-flavour three-jet resonances in pp collisions at √s = 8 TeV

A search for three-jet hadronic resonance production in pp collisions at a centre-of-mass energy of 8 TeV has been conducted by the CMS Collaboration at the LHC with a data sample corresponding to an integrated luminosity of 19.4 fb−1. The search method is model independent, and events are selected that have high jet multiplicity and large values of jet transverse momenta. The signal models explored assume R-parity-violating supersymmetric gluino pair production and have final states with either only light-flavour jets or both light- and heavy- flavour jets. No significant deviation is found between the selected events and the expected standard model multijet and tt background. For a gluino decaying into light-flavour jets, a lower limit of 650 GeV on the gluino mass is set at a 95% confidence level, and for a gluino decaying into one heavy- and two light- flavour jets, gluino masses between 200 and 835 GeV are, for the first time, likewise excluded
Molding direction constraints in structural optimization via a level-set method

International audienceIn the framework of structural optimization via a level-set method, we develop an approach to handle the directional molding constraint for cast parts. A novel molding condition is formulated and a penalization method is used to enforce the constraint. A first advantage of our new approach is that it does not require to start from a feasible initialization, but it guarantees the convergence to a castable shape. A second advantage is that our approach can incorporate thickness constraints too. We do not adress the optimization of the casting system, which is considered a priori defined. We show several 3d examples of compliance minimization in linearized elasticity under molding and minimal or maximal thickness constraints. We also compare our results with formulations already existing in the literature
Hierarchical cooperativity mediated by chromatin remodeling; the model of the MMTV transcription regulation.

International audienceChromatin remodeling machineries are abundant and diverse in eukaryotic cells but their importance in gene expression remains unclear. Although the influence of nucleosome position on the regulation of gene expression is generally envisioned under the equilibrium perspective, it is proposed that given the ATP-dependence of chromatin remodeling enzymes, certain mechanisms necessitate non-equilibrium treatments. In particular, examination of the celebrated chromatin remodeling system of the mouse mammary tumor virus, in which the binding of transcription factors opens the way to other ones, reveals that breaking equilibrium offers a subtle mode of transcription factor cooperativity, avoids molecular trapping phenomena and allows to reconcile previously conflicting experimental data. The mechanism proposed here provides a control lever of promoter sensitivity and responsiveness, increasing the discernment of gene expression
Breaking the VE-cadherin bonds.

International audienceExchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. Indeed, a growing number of permeability inducing factors (PIFs) was shown to elicit signaling mechanisms culminating in VE-cadherin destabilization and global alteration of the junctional architecture. Conversely, anti-PIFs protect from VE-cadherin disruption and enhance cell cohesion. These findings provide evidence on how endothelial cell-cell junctions impact the vascular network, and change our perception about normal and aberrant angiogenesis
Pulse radiolysis studies on superoxide reductase from Treponema pallidum.

International audienceSuperoxide reductases (SORs) are small metalloenzymes, which catalyze reduction of O2*- to H2O2. The reaction of the enzyme from Treponema pallidum with superoxide was studied by pulse radiolysis methods. The first step is an extremely fast bi-molecular reaction of the ferrous center with O2, with a rate constant of 6 x 10 (8) M(-1) s(-1). A first intermediate is formed which is converted to a second one with a slower rate constant of 4800 s(-1). This latter value is 10 times higher than the corresponding one previously reported in the case of SOR from Desulfoarculus baarsii. The reconstituted spectra for the two intermediates are consistent with formation of transient iron-peroxide species