pinecone/core-2020-05-10-deduplication huggingface dataset:
Investigation of photoplethysmmographic signals and arterial blood oxygen saturation values (SpO(2)) during blood pressure cuff-induced hypoperfusion

Photoplethysmography is a non-invasive electro-optical technique widely used in the study and monitoring of the pulsations associated with changes in blood volume in a peripheral vascular bed. Photoplethysmography is used in the estimation of arterial oxygen saturation (SpO2) by pulse oximetry. A reflectance finger photoplethysmographic (PPG) probe and a multiplexed data acquisition system operating simultaneously at two wavelengths and incorporating an external lead II electrocardiogram (ECG) reference channel, and a commercial finger pulse oximeter has been developed. The aim of this study is to investigate the morphology and amplitude of PPG signals and its effect on pulse oximetry during blood pressure cuff-induced hypoperfusion. PPG signals and SpO2s and standard ECG traces were obtained from 14 healthy volunteers and displayed on a personal computer. Measurable PPG signals at both infrared and red wavelengths were obtained from all induced pressures prior to full brachial occlusion. There are statistically significant differences between the ac PPGs in the low pressures (0 to 80 mmHg) than those in the upper pressures (90 to 150 mmHg) at both wavelengths. Both pulse oximeters showed gradual decrease of saturations during induced hypoperfusion which demonstrate the direct relation between blood volumes (PPG amplitudes), arterial vessel stenosis and blood oxygen saturation. The custom made pulse oximeter was found to be more sensitive to SpO2 changes than the commercial pulse oximeter especially at high occluding pressures
From $\Xi_b \to \Lambda_b \pi$ to $\Xi_c \to \Lambda_c \pi$

Using a successful framework for describing S-wave hadronic decays of light
hyperons induced by a subprocess $s \to u (\bar u d)$, we presented recently a
model-independent calculation of the amplitude and branching ratio for $\Xi^-_b
\to \Lambda_b \pi^-$ in agreement with a LHCb measurement. The same quark
process contributes to $\Xi^0_c \to \Lambda_c \pi^-$, while a second term from
the subprocess $cs \to cd$ has been related by Voloshin to differences among
total decay rates of charmed baryons. We calculate this term and find it to
have a magnitude approximately equal to the $s \to u (\bar u d)$ term. We argue
for a negligible relative phase between these two contributions, potentially
due to final state interactions. However, we do not know whether they interfere
destructively or constructively. For constructive interference one predicts
${\cal B}(\Xi_c^0 \to \Lambda_c \pi^-) = (1.94 \pm 0.70)\times 10^{-3}$ and
${\cal B}(\Xi_c^+ \to \Lambda_c \pi^0) = (3.86 \pm 1.35)\times 10^{-3}$. For
destructive interference, the respective branching fractions are expected to be
less than about $10^{-4}$ and $2 \times 10^{-4}$.Comment: To be published in Physics Letters
Search for new resonances in events with one lepton and missing
  transverse momentum in $pp$ collisions at $\sqrt{s} = 13$ TeV with the ATLAS
  detector

A search for $W^\prime$ bosons in events with one lepton (electron or muon)
and missing transverse momentum is presented. The search uses 3.2 fb$^{-1}$ of
$pp$ collision data collected at $\sqrt{s} = 13$ TeV by the ATLAS experiment at
the LHC in 2015. The transverse mass distribution is examined and no
significant excess of events above the level expected from Standard Model
processes is observed. Upper limits on the $W^\prime$ boson cross-section times
branching ratio to leptons are set as a function of the $W^\prime$ mass.
Assuming a $W^\prime$ boson as predicted by the Sequential Standard Model,
$W^\prime$ masses below 4.07 TeV are excluded at the 95% confidence level. This
extends the limit set using LHC data at $\sqrt{s}=8$ TeV by around 800 GeV.Comment: 15 pages plus author list (32 pages total), 4 figures, 3 tables,
  final version published in PLB, All figures including auxiliary figures are
  available at
  http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2015-06/ Data
  points available at HepData: http://hepdata.cedar.ac.uk/view/ins146907
Tracing VAT-2008 program participants’ self development: Effect of social work program undergraduates intervention strategies

Research regarding violence amongst youth and teenagers had suggested the importance of designing and implementing effective intervention programs that takes into account the participants’ specific needs of the teenagers.The purpose of the study: to identify the effect of the VAT-2008 program on teenagers who were categorized as high-risk teenagers by their respective schools; to identify the VAT-2008 participants’ self development from the sosio-economy, values and personality aspects; to determine the factors that constraint the VAT-2008 participants from changing their attitudes.What are the effect of the VAT-2008 program on the high-risk school teenagers from the aspects of their self-development socio-economy, values, personality and change in attitude? This study was framed within the descriptive qualitative research approach.It adopted the exploratory field work research design in which primary data was collected via the open-ended questionnaires and supplemented by performing face-to-face interviews, using interview schedule which was constructed by the researchers, with the participants and their parents and/or family members.A significant percentage of the participants reported the VAT-2008 program had positively impact on their feelings of self-worth, level of confidence, and made them become a more independent and responsible individual.Participants had also confided that they become more responsible to their families and had realized the importance of working their ways to towards attaining a better and comfortable life.Each participant's case is unique.Despite reporting the positive impact of the program on them, nevertheless their experience participating in the VAT-2008 program had qualitatively different effect on their their self-development, socio-economy, values, personality and attitude. The interventions strategies implemented by the Social-Work undergraduates had indeed significantly touched their life journey
Search for heavy lepton resonances decaying to a Z boson and a lepton in pp collisions at root s = 8 TeV with the ATLAS detector

Çetin, Serkant Ali (Dogus Author)A search for heavy leptons decaying to a Z boson and an electron or a muon is presented. The search is based on pp collision data taken at (Formula presented.) = 8 TeV by the ATLAS experiment at the CERN Large Hadron Collider, corresponding to an integrated luminosity of 20.3 fb−1. Three high-transverse-momentum electrons or muons are selected, with two of them required to be consistent with originating from a Z boson decay. No significant excess above Standard Model background predictions is observed, and 95% confidence level limits on the production cross section of high-mass trilepton resonances are derived. The results are interpreted in the context of vector-like lepton and type-III seesaw models. For the vector-like lepton model, most heavy lepton mass values in the range 114–176 GeV are excluded. For the type-III seesaw model, most mass values in the range 100–468 GeV are excluded
Search for a very light NMSSM Higgs boson produced in decays of the 125 GeV scalar boson and decaying into tau leptons in pp collisions at sqrt(s) = 8 TeV

A search for a very light Higgs boson decaying into a pair of τ leptons is presented within the framework of the next-to-minimal supersymmetric standard model. This search is based on a data set corresponding to an integrated luminosity of 19.7 fb−1 of proton-proton collisions collected by the CMS experiment at a centre-of-mass energy of 8 TeV. The signal is defined by the production of either of the two lightest scalars, h1 or h2, via gluon-gluon fusion and subsequent decay into a pair of the lightest Higgs bosons, a1 or h1. The h1 or h2 boson is identified with the observed state at a mass of 125 GeV. The analysis searches for decays of the a1 (h1) states into pairs of τ leptons and covers a mass range for the a1 (h1) boson of 4 to 8 GeV. The search reveals no significant excess in data above standard model background expectations, and an upper limit is set on the signal production cross section times branching fraction as a function of the a1 (h1) boson mass. The 95% confidence level limit ranges from 4.5 pb at ma1 (mh1)=8 GeV to 10.3 pb at ma1 (mh1)=5 GeV
Deglycosylation Step to Improve the Identification of Egg Proteins in\ud
Art Samples

A deglycosylation step using Peptide-N-Glycosidase F (PNGaseF) has been introduced in a standard proteomic protocol to more confidently identify egg based binders. The ingenuity of introducing a PNGaseF digestion was aimed at removing the molecular hindrance, made up by the heavily glycosylated egg proteins, before the protease(s) hydrolysis. This novelty in the protocol resulted in obtaining a significant increase of proteolytic egg peptides thus improving the quality and reliability of egg identification in artwork samples. The protocol has been set up on paint replicas and successfully tested on two historical samples of different origi
Impact of Dreissena fouling on the physiological condition of native and invasive bivalves : interspecific and temporal variations

The impact of Dreissena fouling on unionids
has hardly been studied in Europe, despite the fact
that in some ecosystems (e.g. Lake Balaton, Hungary)
infestations of several hundreds to a thousand individuals
per unionid have been observed. At present,
the zebra mussel Dreissena polymorpha is a dominant
species in Lake Balaton and in the last decade three
other invasive bivalves were introduced, potentially
increasing the pressure on native unionid survival. We
examined whether the fouling of dreissenids (zebra
and quagga (D. rostriformis bugensis) mussels) has a
negative impact on native (Anodonta anatina, Unio
pictorum and U. tumidus) and invasive (Corbicula
fluminea and Sinanodonta woodiana) bivalves and
whether there are any interspecific and temporal
variations in fouling intensity and physiological
condition measured by standard condition index and
glycogen content. A significant negative impact was detected on native unionids only in July and September
(no impact was detected in May), when the fouling
rate was high. For invasive species, a significant
negative impact was detected on S. woodiana with a
high level of dressenid infestation; whereas no significant
impact was detected on C. fluminea. Overall, this
study confirms that Dreissena may threaten unionid
species including the invasive S. woodiana, although
high interspecific and temporal variations were
observed. This situation should be taken into account
in future ecological and conservational assessments
because species respond differently to Dreissena
fouling and effects seem to be more pronounced in
late summer/early autumn. In addition, this study
provides the first evidence that the invasive C.
fluminea appear to be less vulnerable to dressenid
fouling.The study was supported by the Hungarian Scientific Fund (KTIA-OTKA) under the contract No. CNK80140
Dynamics of isolated-photon plus jet production in pp collisions at (√s)=7 TeV with the ATLAS detector

The dynamics of isolated-photon plus jet production in pp   collisions at a centre-of-mass energy of 7 TeV has been studied with the ATLAS detector at the LHC using an integrated luminosity of 37 pb−1. Measurements of isolated-photon plus jet bin-averaged cross sections are presented as functions of photon transverse energy, jet transverse momentum and jet rapidity. In addition, the bin-averaged cross sections as functions of the difference between the azimuthal angles of the photon and the jet, the photon–jet invariant mass and the scattering angle in the photon–jet centre-of-mass frame have been measured. Next-to-leading-order QCD calculations are compared to the measurements and provide a good description of the data, except for the case of the azimuthal opening angle.We acknowledge the support of NPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America
Search for first generation scalar leptoquarks in pp collisions at √s=7 TeV with the ATLAS detector

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMWe report a search for first generation scalar leptoquarks using 1.03 fb−1 of proton–proton collisions data produced by the Large Hadron Collider at √ s = 7 TeV and recorded by the ATLAS experiment. Leptoquarks are sought via their decay into an electron or neutrino and a quark, producing events with two oppositely charged electrons and at least two jets, or events with an electron, missing transverse momentum and at least two jets. Control data samples are used to validate background predictions from Monte Carlo simulation. In the signal region, the observed event yields are consistent with the background expectations. We exclude at 95% confidence level the production of first generation scalar leptoquark with masses mLQ < 660 (607) GeV when assuming the branching fraction of a leptoquark to a charged lepton is equal to 1.0 (0.5)We thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; ARTEMIS, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNAS, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN and the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA) and in the Tier-2 facilities worldwid
Electrons, holes, and excitons in GaAs polytype quantum dots

Single and multi-band k⋅p Hamiltonians for GaAs crystal phase quantum dots are used to assess ongoing experimental activity on the role of such factors as quantum confinement, spontaneous polarization,valence band mixing, and exciton Coulomb interaction. Spontaneous polarization is found to be a dominating term. Together with the control of dot thickness [Vainorius et al., Nano Lett. 15, 2652 (2015)], it enables wide exciton wavelength and lifetime tunability. Several new phenomena are predicted for small diameter dots [Loitsch et al., Adv. Mater. 27, 2195 (2015)], including non-heavy hole ground state, strong hole spin admixture, and a type-II to type-I exciton transition, which can be used to improve the absorption strength and reduce the radiative lifetime of GaAs polytypes.We are grateful to P. Caroff, M. E. Pistol, and B. Loitsch for useful discussions. Support from UJI Project No. P1-1B2014-24, MINECO Project No. CTQ2014-60178-P, and a FPU grant (C.S.) is acknowledged
Bipartite Field Theories: from D-Brane Probes to Scattering Amplitudes

We introduce and initiate the investigation of a general class of 4d, N=1
quiver gauge theories whose Lagrangian is defined by a bipartite graph on a
Riemann surface, with or without boundaries. We refer to such class of theories
as Bipartite Field Theories (BFTs). BFTs underlie a wide spectrum of
interesting physical systems, including: D3-branes probing toric Calabi-Yau
3-folds, their mirror configurations of D6-branes, cluster integrable systems
in (0+1) dimensions and leading singularities in scattering amplitudes for N=4
SYM. While our discussion is fully general, we focus on models that are
relevant for scattering amplitudes. We investigate the BFT perspective on graph
modifications, the emergence of Calabi-Yau manifolds (which arise as the master
and moduli spaces of BFTs), the translation between square moves in the graph
and Seiberg duality and the identification of dual theories by means of the
underlying Calabi-Yaus, the phenomenon of loop reduction and the interpretation
of the boundary operator for cells in the positive Grassmannian as higgsing in
the BFT. We develop a technique based on generalized Kasteleyn matrices that
permits an efficient determination of the Calabi-Yau geometries associated to
arbitrary graphs. Our techniques allow us to go beyond the planar limit by both
increasing the number of boundaries of the graphs and the genus of the
underlying Riemann surface. Our investigation suggests a central role for
Calabi-Yau manifolds in the context of leading singularities, whose full scope
is yet to be uncovered.Comment: 58 pages. Typos fixe
Control of emitted light polarization in a 1310nm dilute nitride spin-vertical cavity surface emitting laser subject to circularly polarized optical injection

© 2014 AIP Publishing LLC. We experimentally demonstrate the control of the light polarization emitted by a 1310 nm dilute nitride spin-Vertical Cavity Surface Emitting Laser (VCSEL) at room temperature. This is achieved by means of a combination of polarized optical pumping and polarized optical injection. Without external injection, the polarization of the optical pump controls that of the spin-VCSEL. However, the addition of the externally injected signal polarized with either left- (LCP) or rightcircular polarization (RCP) is able to control the polarization of the spin-VCSEL switching it at will to left- or right-circular polarization. A numerical model has been developed showing a very high degree of agreement with the experimental findings
Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis

This is the final version of the article. Available from the publisher via the DOI in this record.Using a decision-analytic model, we evaluated the effectiveness and cost-effectiveness of surveillance for hepatocellular carcinoma (HCC) in individuals with cirrhosis. Separate cohorts with cirrhosis due to alcoholic liver disease, hepatitis B and hepatitis C were simulated. Results were also combined to approximate a mixed aetiology population. Comparisons were made between a variety of surveillance algorithms using alpha-foetoprotein (AFP) assay and/or ultrasound at 6- and 12-monthly intervals. Parameter estimates were obtained from comprehensive literature reviews. Uncertainty was explored using one-way and probabilistic sensitivity analyses. In the mixed aetiology cohort, 6-monthly AFP+ultrasound was predicted to be the most effective strategy. The model estimates that, compared with no surveillance, this strategy may triple the number of people with operable tumours at diagnosis and almost halve the number of people who die from HCC. The cheapest strategy employed triage with annual AFP (incremental cost-effectiveness ratio (ICER): 20,700 pounds per quality-adjusted life-year (QALY) gained). At a willingness-to-pay threshold of 30,000 pounds per QALY the most cost-effective strategy used triage with 6-monthly AFP (ICER: 27,600 pounds per QALY gained). The addition of ultrasound to this strategy increased the ICER to 60,100 pounds per QALY gained. Surveillance appears most cost-effective in individuals with hepatitis B-related cirrhosis, potentially due to younger age at diagnosis of cirrhosis. Our results suggest that, in a UK NHS context, surveillance of individuals with cirrhosis for HCC should be considered effective and cost-effective. The economic efficiency of different surveillance strategies is predicted to vary markedly according to cirrhosis aetiology.This work is part of a larger project commissioned by the UK NHS
R&D HTA Programme (Project reference number 05/31/01
Modulation of Glucagon Receptor Pharmacology by RAMP2

The glucagon and glucagon-like peptide-1 (GLP-1) receptors play important, opposing roles in regulating blood glucose levels. Consequently, these receptors have been identified as targets for novel diabetes treatments. However, drugs acting at the GLP-1 receptor, whilst having clinical efficacy, have been associated with severe adverse side-effects and targeting of the glucagon receptor has yet to be successful. Here we use a combination of yeast reporter assays and mammalian systems, to provide a more complete understanding of glucagon receptor signaling considering the effect of multiple ligands, association with the receptor-interacting protein, receptor activity modifying protein-2 (RAMP2) and individual G protein α-subunits. We demonstrate that RAMP2 alters both ligand selectivity and G protein preference of the glucagon receptor. Importantly, we also uncover novel cross-reactivity of therapeutically used GLP-1 receptor ligands at the glucagon receptor that is abolished by RAMP2 interaction. This study reveals the glucagon receptor as a previously unidentified target for GLP-1 receptor agonists and highlights a role for RAMP2 in regulating its pharmacology. Such previously unrecognized functions of RAMPs highlight the need to consider all receptor-interacting proteins in future drug development.This work was supported by a Warwick Impact Fund (C.W., G.L.), the BBSRC (G.L. - BB/G01227X/1), (T.S., G.R., D.R. - BB/F008392/1), (D.P. - BB/M007529/1 and BB/M000176/1), Warwick Research Development Fund (C.W., G.L.) grant number (RD13301) and the Birmingham Science City Research Alliance (G.L).This is the final version of the article. It first appeared from ASBMB at http://dx.doi.org/10.1074/jbc.M114.62460
Search for new physics in events with same-sign dileptons and b-tagged jets in pp collisions at √s = 7 TeV

A search for new physics is performed using isolated same-sign dileptons with at least two b-quark jets in the final state. Results are based on a 4.98 fb[superscript −1] sample of proton-proton collisions at a centre-of-mass energy of 7 TeV collected by the CMS detector. No excess above the standard model background is observed. Upper limits at 95% confidence level are set on the number of events from non-standard-model sources. These limits are used to set constraints on a number of new physics models. Information on acceptance and efficiencies are also provided so that the results can be used to confront additional models in an approximate way.United States. Dept. of EnergyNational Science Foundation (U.S.