pinecone/core-2020-05-10-deduplication huggingface dataset:
Processing and characterisation of II–VI ZnCdMgSe thin film gain structures

AbstractLattice-matched II–VI selenide quantum well (QW) structures grown on InP substrates can be designed for emission throughout the visible spectrum. InP has, however, strong visible-light absorption, so that a method for epitaxial lift-off and transfer to transparent substrates is desirable for vertically-integrated devices. We have designed and grown, via molecular beam epitaxy, ZnCdSe/ZnCdMgSe multi-QW gain regions for vertical emission, with the QWs positioned for resonant periodic gain. The release of the 2.7μm-thick ZnCdSe/ZnCdMgSe multi-QW film is achieved via selective wet etching of the substrate and buffer layers leaving only the epitaxial layers, which are subsequently transferred to transparent substrates, including glass and thermally-conductive diamond. Post-transfer properties are investigated, with power and temperature-dependent surface- and edge-emitting photoluminescence measurements demonstrating no observable strain relaxation effects or significant shift in comparison to unprocessed samples. The temperature dependent QW emission shift is found experimentally to be 0.13nm/K. Samples capillary-bonded epitaxial-side to glass exhibited a 6nm redshift under optical pumping of up to 35mW at 405nm, corresponding to a 46K temperature increase in the pumped region; whereas those bonded to diamond exhibited no shift in QW emission, and thus efficient transfer of the heat from the pumped region. Atomic force microscopy analysis of the etched surface reveals a root-mean-square roughness of 3.6nm. High quality optical interfaces are required to establish a good thermal and optical contact for high power optically pumped laser applications
Evaluation of functional capacity for exercise in children and adolescents with sickle-cell disease through the six-minute walk test

AbstractObjectiveTo evaluate lung functional capacity (FC) for physical exercise in children and adolescents with sickle cell disease (SCD) through the six-minute walk test (6MWT).MethodA cross-sectional prospective study was performed to evaluate the FC of 46 patients with SCD through the 6MWT. The following parameters were assessed: heart rate (HR), respiratory rate (RR), peripheral pulse oxygen saturation (SpO2), peak expiratory flow (PEF), blood pressure (systolic and diastolic), dyspnea, and leg fatigue (modified Borg scale) at rest, in the end of the test, and ten minutes after the 6MWT. The total distance walked was also recorded. For statistical analysis, the parametric variables were analyzed using the paired Student's t-test, analysis of variance (ANOVA), and Bonferroni multiple comparisons, with a significance level set at p ≤ 0.05.ResultsThe 46 patients were aged age 9.15±3.06 years, presented baseline Hb of 9.49±1.67g/dL, and walked 480.89±68.70 m. SCD diagnosis was as follows: group 1- HbSS (n=20)/HbSβ0-thalassemia (n=3) and group 2 - HbSC (n=20)/HbSβ+-thalassemia (n=3). Regarding total distance walked, patients in group 1 walked a shorter distance than patients in group 2 (459.39±57.19 vs. 502.39±73.60 m; p=0.032). There was no statistical difference regarding PEF in the three moments of evaluation. The SpO2 in ambient air and SpO2 with O2 differed between groups 1 and 2 (p<0.001 vs. p=0.002), as well as the RR (p=0.001).ConclusionThese patients showed a lower FC for exercise than that predicted for the age range in the literature. Patients diagnosed with HbSS/Sβ0-thalassemia had a lower performance in the test than those with HbSC/Sβ+-thalassemia regarding total distance walked, RR, and SpO2 after the 6MWT
University access and after: explaining the social composition of degree programmes and the contrasting expectations of students

University expansion in higher education has been hierarchically differentiated. There is some concentration of certain social profiles in some degrees of study, so social composition between degrees can vary considerably. This article describes in terms of social composition 10 degrees of four public universities in the metropolitan area of Barcelona. We analyse 857 questionnaires filled in by mid-career students. From the perspective of agent's decision on the choice of studies, we explore what were the factors that made them choose a concrete degree. We examine several variables that can indicate whether their expectations have been met or not. The results show that the factors predicted by the theory by which working-class (WC) students choose degrees instrumental motivations and conditions that minimize the risk are often met. In this regard, the recent structural reform related with the implementation of the European Higher Education Area that removes short-cycles degrees (3 years) could lead to a problem of access for WC students
Frequency-resolved Monte Carlo

We adapt the Quantum Monte Carlo method to the cascaded formalism of quantum
optics, allowing us to simulate the emission of photons of known energy.
Statistical processing of the photon clicks thus collected agrees with the
theory of frequency-resolved photon correlations, extending the range of
applications based on correlations of photons of prescribed energy, in
particular those of a photon-counting character. We apply the technique to
autocorrelations of photon streams from a two-level system under coherent and
incoherent pumping, including the Mollow triplet regime where we demonstrate
the direct manifestation of leapfrog processes in producing an increased rate
of two-photon emission events.Comment: 20 pages, 7 figure
Correlations between jets and charged particles in PbPb and pp collisions at sNN=2.76 TeV

The quark-gluon plasma is studied via medium-induced changes to correlations between jets and charged particles in PbPb collisions compared to pp reference data. This analysis uses data sets from PbPb and pp collisions with integrated luminosities of 166 μb−1 and 5.3 pb−1, respectively, collected at (Formula presented.) TeV. The angular distributions of charged particles are studied as a function of relative pseudorapidity (Δη) and relative azimuthal angle (Δϕ) with respect to reconstructed jet directions. Charged particles are correlated with all jets with transverse momentum (pT) above 120 GeV, and with the leading and subleading jets (the highest and second-highest in pT, respectively) in a selection of back-to-back dijet events. Modifications in PbPb data relative to pp reference data are characterized as a function of PbPb collision centrality and charged particle pT. A centrality-dependent excess of low-pT particles is present for all jets studied, and is most pronounced in the most central events. This excess of low-pT particles follows a Gaussian-like distribution around the jet axis, and extends to large relative angles of Δη ≈ 1 and Δϕ ≈ 1.[Figure not available: see fulltext.]The Scientific and Technical Research Council of Turkey, and Turkish Atomic Energy Authorit
Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)

Aims/hypothesis\ud
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Rapamycin (sirolimus) is one of the primary immunosuppressants for islet transplantation. Yet there is evidence that the long-term treatment of islet-transplant patients with rapamycin may be responsible for subsequent loss of islet graft function and viability. Therefore, the primary objective of this study was to elucidate the molecular mechanism of rapamycin toxicity in beta cells.\ud
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Methods\ud
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Experiments were performed on isolated rat and human islets of Langerhans and MIN6 cells. The effects of rapamycin and the roles of mammalian target of rapamycin complex 2 (mTORC2)/protein kinase B (PKB) on beta cell signalling, function and viability were investigated using cell viability assays, insulin ELISA assays, kinase assays, western blotting, pharmacological inhibitors, small interfering (si)RNA and through the overproduction of a constitutively active mutant of PKB.\ud
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Results\ud
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Rapamycin treatment of MIN6 cells and islets of Langerhans resulted in a loss of cell function and viability. Although rapamycin acutely inhibited mTOR complex 1 (mTORC1), the toxic effects of rapamycin were more closely correlated to the dissociation and inactivation of mTORC2 and the inhibition of PKB. Indeed, the overproduction of constitutively active PKB protected islets from rapamycin toxicity whereas the inhibition of PKB led to a loss of cell viability. Moreover, the selective inactivation of mTORC2 using siRNA directed towards rapamycin-insensitive companion of target of rapamycin (RICTOR), mimicked the toxic effects of chronic rapamycin treatment.\ud
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Conclusions/interpretation\ud
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This report provides evidence that rapamycin toxicity is mediated by the inactivation of mTORC2 and the inhibition of PKB and thus reveals the molecular basis of rapamycin toxicity and the essential role of mTORC2 in maintaining beta cell function and survival
Prometheus induced vorticity in Saturn’s F ring

Saturn’s rings are known to show remarkable real time variability in their structure. Many of which can be associated to interactions with nearby moons and moonlets. Possibly the most interesting and dynamic place in the rings, probably in the whole Solar System, is the F ring. A highly disrupted ring with large asymmetries both radially and azimuthally. Numerically non-zero components to the curl of the velocity vector field (vorticity) in the perturbed area of the F ring post encounter are witnessed, significantly above the background vorticity. Within the perturbed area rich distributions of local rotations is seen located in and around the channel edges. The gravitational scattering of ring particles during the encounter causes a significant elevated curl of the vector field above the background F ring vorticity for the first 1–3 orbital periods post encounter. After 3 orbital periods vorticity reverts quite quickly to near background levels. This new found dynamical vortex life of the ring will be of great interest to planet and planetesimals in proto-planetary disks where vortices and turbulence are suspected of having a significant role in their formation and migrations. Additionally, it is found that the immediate channel edges created by the close passage of Prometheus actually show high radial dispersions in the order ~20–50 cm/s, up to a maximum of 1 m/s. This is much greater than the value required by Toomre for a disk to be unstable to the growth of axisymmetric oscillations. However, an area a few hundred km away from the edge shows a more promising location for the growth of coherent objects
Simulations of the effect of waveguide cross-section on quantum dot – plasmon coupling

Quantum dot - plasmon waveguide systems are of interest for the active control of plasmon propagation, and consequently, the development of active nanophotonic devices such as nano-sized optical transistors. This paper is concerned with how varying aspect ratio of the waveguide crosssection affects the quantum dot - plasmon coupling. We compare a stripe waveguide with an equivalent nanowire, illustrating that both waveguides have a similar coupling strength to a nearby quantum dot for small waveguide cross-section, thereby indicating that stripe lithographic waveguides have strong potential use in quantum dot –plasmon waveguide systems. We also demonstrate that changing the aspect ratio of both stripe and wire waveguides can increase the spontaneous emission rate of the quantum dot into the plasmon mode, by up to a factor of five. The results of this paper will contribute to the optimisation of quantum dot - plasmon waveguide systems and help pave the way for the development of active nanophotonics devices
Cosmogenic exposure age constraints on deglaciation and flow behaviour of a marine-based ice stream in western Scotland, 21–16 ka.

Understanding how marine-based ice streams operated during episodes of deglaciation requires geochronological data that constrain both timing of deglaciation and changes in their flow behaviour, such as that from unconstrained ice streaming to topographically restricted flow. We present seventeen new 10Be exposure ages from glacial boulders and bedrock at sites in western Scotland within the area drained by the Hebrides Ice Stream, a marine-based ice stream that drained a large proportion of the former British-Irish Ice Sheet. Exposure ages from Tiree constrain deglaciation of a topographic high within the central zone of the ice stream, from which convergent flowsets were produced during ice streaming. These ages thus constrain thinning of the Hebrides Ice Stream, which, on the basis of supporting information, we infer to represent cessation of ice streaming at 20.6 ± 1.2 ka, 3–4 ka earlier than previously inferred. A period of more topographically restricted flow produced flow indicators superimposed on those relating to full ice stream conditions, and exposure ages from up-stream of these constrain deglaciation to 17.5 ± 1.0 ka. Complete deglaciation of the marine sector of the Hebrides Ice Stream occurred by 17–16 ka at which time the ice margin was located near the present coastline. Exposure ages from the southernmost Outer Hebrides (Mingulay and Barra) indicate deglaciation at 18.9 ± 1.0 and 17.1 ± 1.0 ka respectively, demonstrating that an independent ice cap persisted on the southern Outer Hebrides for 3–4 ka after initial ice stream deglaciation. This suggests that deglaciation of the Hebrides Ice Stream was focused along major submarine troughs. Collectively, our data constrain initial deglaciation and changes in flow regime of the Hebrides Ice Stream, final deglaciation of its marine sector, and deglaciation of the southern portion of the independent Outer Hebrides Ice Cap, providing chronological constraints on future numerical reconstructions of this key sector of the former British-Irish Ice Sheet
Strange particle production in pp collisions at √s = 0.9 and 7 TeV

The spectra of strange hadrons are measured in proton-proton collisions, recorded by the CMS experiment at the CERN LHC, at centre-of-mass energies of 0.9 and 7 TeV. The K^0_s, Lambda, and Xi^- particles and their antiparticles are reconstructed from their decay topologies and the production rates are measured as functions of rapidity and transverse momentum. The results are compared to other experiments and to predictions of the PYTHIA Monte Carlo program. The transverse momentum distributions are found to differ substantially from the PYTHIA results and the production rates exceed the predictions by up to a factor of three
Search for microscopic black holes in pp collisions at \sqrt{s} = 7 TeV

A search for microscopic black holes in pp collisions at a center-of-mass energy of 7 TeV is presented. The data sample corresponds to an integrated luminosity of 4.7 fb−1 recorded by the CMS experiment at the LHC in 2011. Events with large total transverse energy have been analyzed for the presence of multiple energetic jets, leptons, and photons, which are typical signals of evaporating semiclassical and quantum black holes, and string balls. Agreement with the expected standard model backgrounds, which are dominated by QCD multijet production, has been observed for various combined multiplicities of jets and other reconstructed objects in the final state. Model-independent limits are set on new physics processes producing high-multiplicity, energetic final states. In addition, new model-specific indicative limits are set excluding semiclassical and quantum black holes with masses below 3.8 to 5.3 TeV and string balls with masses below 4.6 to 4.8 TeV . The analysis has a substantially increased sensitivity compared to previous searches
Profiling a decade of Information Systems Frontiers' research

Post-print version. Final version published by Springer; available online at http://link.springer.com/This article analyses the first ten years of research published in the Information Systems Frontiers (ISF) from 1999 to 2008. The analysis of the published material includes examining variables such as most productive authors, citation analysis, universities associated with the most publications, geographic diversity, authors‟ backgrounds and research methods. The keyword analysis suggests that ISF research has evolved from establishing concepts and domain of information systems (IS), technology and management to contemporary issues such as outsourcing, web services and security. The analysis presented in this paper has identified intellectually significant studies that have contributed to the development and accumulation of intellectual wealth of ISF. The analysis has also identified authors published in other journals whose work largely shaped and guided the researchers published in ISF. This research has implications for researchers, journal editors, and research institutions
Non-resonant and electroweak NNLO correction to the $e^+ e^-$ top
  anti-top threshold

We determine the NNLO electroweak correction to the $e^+ e^-\to
b\bar{b}W^+W^- X$ production cross section near the top-pair production
threshold. The calculation includes non-resonant production of the final state
as well as electroweak effects in resonant top anti-top pair production with
non-relativistic resummation, and elevates the theoretical prediction to NNNLO
QCD plus NNLO electroweak accuracy. We then study the impact of the new
contributions on the top-pair threshold scan at a future lepton collider.Comment: 67 pages, v2: published versio
Search for standard model production of four top quarks in proton-proton collisions at $\sqrt{s} = 13$ TeV

A search for events containing four top quarks ($t\overline tt\overline t$) is reported from proton–proton collisions recorded by the CMS experiment at $\sqrt{s} = 13$ TeV and corresponding to an integrated luminosity of 2.6 $fb^{−1}$. The analysis considers the single-lepton (e or μ)+jets and the opposite-sign dilepton ($μ^+μ^−, μ^±e^∓$, or $e^+e^−)$+jets channels. It uses boosted decision trees to combine information on the global event and jet properties to distinguish between ($t\overline tt\overline t$) and $t\overline t$ production. The number of events observed after all selection requirements is consistent with expectations from background and standard model signal predictions, and an upper limit is set on the cross section for ($t\overline tt\overline t$) production in the standard model of 94 fb at 95% confidence level (10.2× the prediction), with an expected limit of 118 fb. This is combined with the results from the published CMS search in the same-sign dilepton channel, resulting in an improved limit of 69 fb at 95% confidence level (7.4× the prediction), with an expected limit of 71 fb. These are the strongest constraints on the rate of ($t\overline tt\overline t$) production to date
Perceptions of Organ Donors and Willingness to Donate Organs upon Death: A Test of the Prototype/Willingness Model

Understanding people's organ donation decisions may narrow the gap between organ supply and demand. In two studies, participants who had not recorded their posthumous organ donation decision (Study 1, N = 210; Study 2, N = 307) completed items assessing prototype/willingness model (PWM; attitude, subjective norm, donor prototype favorability and similarity, willingness) constructs. Attitude, subjective norm, and prototype similarity predicted willingness to donate. Prototype favorability and a Prototype Favorability נSimilarity interaction predicted willingness (Study 2). These findings provide support for the PWM in altruistic health contexts, highlighting the importance of people's perceptions about organ donors in their donation decisions.Full Tex
Spatial inequalities in colorectal and breast cancer survival: Premature deaths and associated factors

This study examines the influence of cancer stage, distance to treatment facilities and area disadvantage on breast and colorectal cancer spatial survival inequalities. We also estimate the number of premature deaths after adjusting for cancer stage to quantify the impact of spatial survival inequalities. Population-based descriptive study of residents aged <90 years in Queensland, Australia diagnosed with primary invasive breast (25,202 females) or colorectal (14,690 males, 11,700 females) cancers during 1996-2007. Bayesian hierarchical models explored relative survival inequalities across 478 regions. Cancer stage and disadvantage explained the spatial inequalities in breast cancer survival, however spatial inequalities in colorectal cancer survival persisted after adjustment. Of the 6,019 colorectal cancer deaths within 5 years of diagnosis, 470 (8%) were associated with spatial inequalities in non-diagnostic factors, i.e. factors beyond cancer stage at diagnosis. For breast cancers, of 2,412 deaths, 170 (7%) were related to spatial inequalities in non-diagnostic factors. Quantifying premature deaths can increase incentive for action to reduce these spatial inequalities.Full Tex
Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies

BACKGROUND: Breast cancer risk for postmenopausal women is positively associated with circulating concentrations of oestrogens and androgens, but the determinants of these hormones are not well understood. METHODS: Cross-sectional analyses of breast cancer risk factors and circulating hormone concentrations in more than 6000 postmenopausal women controls in 13 prospective studies. RESULTS: Concentrations of all hormones were lower in older than younger women, with the largest difference for dehydroepiandrosterone sulphate (DHEAS), whereas sex hormone-binding globulin (SHBG) was higher in the older women. Androgens were lower in women with bilateral ovariectomy than in naturally postmenopausal women, with the largest difference for free testosterone. All hormones were higher in obese than lean women, with the largest difference for free oestradiol, whereas SHBG was lower in obese women. Smokers of 15+ cigarettes per day had higher levels of all hormones than non-smokers, with the largest difference for testosterone. Drinkers of 20+ g alcohol per day had higher levels of all hormones, but lower SHBG, than non-drinkers, with the largest difference for DHEAS. Hormone concentrations were not strongly related to age at menarche, parity, age at first full-term pregnancy or family history of breast cancer. CONCLUSION: Sex hormone concentrations were strongly associated with several established or suspected risk factors for breast cancer, and may mediate the effects of these factors on breast cancer risk. British Journal of Cancer (2011) 105, 709-722. doi:10.1038/bjc.2011.254 www.bjcancer.com Published online 19 July 2011 (C) 2011 Cancer Research U
Buildings behaving badly: a behavioral experiment on how different motivational frames influence residential energy label adoption in the Netherlands

Heating buildings contributes to approximately 36 % of Europe’s energy demand and several EU member states have adopted mandatory energy labels to improve energy efficiency by promoting home weatherization investments. This paper focuses on the perception of the energy label for residential buildings in the Netherlands and the role of different frames (egoistic, biospheric and social norms and neutral frames) in motivating adoption of energy labels for housing. We used a behavioral email experiment and an online survey to investigate these motivational factors. We find that biospheric frames are weaker than the other three motivational frames in terms of engaging interest in the energy label, but that the biospheric frame results in higher willingness to pay (WTP) for the energy label. We also find that age (rather than income) correlates with higher WTP for home energy labels