pinecone/core-2020-05-10-deduplication huggingface dataset:
Battery system development - Assembly planning between lightweight design and high volume production

Battery systems of electric vehicles suffer from low energy densities as well as high masses and geometrical complexity. The absence of standards for battery cells and peripheral components in combination with large and distributed design spaces within passenger vehicles open up innumerable possibilities to design battery systems. The results are product specific and uneconomical assembly systems. This paper describes the work of the TU Braunschweig to create a methodology that generates and evaluates modular and easy to assemble battery systems based upon user requirements. This methodology gathers and links requirements between the priorities "lightweight design" and "high volume production" including a partly automated generation of CAD data. The generated concepts are directly used for assembly planning. The presented methodology therefore represents a simultaneous engineering approach that shortens development time and supports design engineers as well as process planners
Socio-gnoseological Issues of Alienation in G. S. Batishchev's Works

In this article, the authors have introduced the gynecological analyses of the category of alienation, the problem of self-knowledge and the ways of its scientific understanding in G.S. Batishchev's works. This time, the authors state that the problem of alienation of personality in modern world is connected with not only just deprivation of attention, but it is also the result of the increased alienation and social problems. The authors have analyzed a number of social relationships, such as social-organic, atomistic, each of which can be further divided into two more classes: utilitarian and pluralistic, polyphonic or harmonic. These classes of relationships are important for understanding of the subject and object, and their interrelations. A particular attention has been paid to social polyphonic ties, which facilitate the advancement of the individual and humanity towards the overcoming of alienation. In addition, the authors have focused their attention on the role of creative activities in the development of social relations. The analyses of relationships described in the works of G.S. Batishchev embark on the way of overcoming of alienation of personality
Cationic State Distribution over the P700 Chlorophyll Pair in Photosystem I

AbstractThe primary electron donor P700 in photosystem I is composed of two chlorophylls, PA and PB. P700 forms the cationic [PA/PB]•+ state as a result of light-induced electron transfer. We obtained a PA•+/PB•+ ratio of 28:72 and a spin distribution of 22:78 for the entire PSI protein-pigment complex. By considering the influence of the protein components on the redox potential for one-electron oxidation of PA/PB monomers, we found that the following three factors significantly contributed to a large PB•+ population relative to PA•+: 1), Thr-A743 forming a H-bond with PA; 2), PA as a chlorophyll a epimer; and 3), a conserved PsaA/PsaB pair, the Arg-A750/Ser-B734 residue. In addition, 4), the methyl-ester groups of the accessory chlorophylls A−1A/A−1B significantly stabilized the cationic [PA/PB]•+ state and 5), the methyl-ester group orientations were completely different in A−1A and A−1B as seen in the crystal structure. When the methyl-ester group was rotated, the spin-density distribution over PA/PB ranged from 22:78 to 15:85
Search for pair-produced resonances decaying to jet pairs in proton–proton collisions at s=8 TeV

AbstractResults are reported of a general search for pair production of heavy resonances decaying to pairs of hadronic jets in events with at least four jets. The study is based on up to 19.4 fb−1 of integrated luminosity from proton–proton collisions at a center-of-mass energy of 8 TeV, recorded with the CMS detector at the LHC. Limits are determined on the production of scalar top quarks (top squarks) in the framework of R-parity violating supersymmetry and on the production of color-octet vector bosons (colorons). First limits at the LHC are placed on top squark production for two scenarios. The first assumes decay to a bottom quark and a light-flavor quark and is excluded for masses between 200 and 385 GeV, and the second assumes decay to a pair of light-flavor quarks and is excluded for masses between 200 and 350 GeV at 95% confidence level. Previous limits on colorons decaying to light-flavor quarks are extended to exclude masses from 200 to 835 GeV
Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6

AbstractThe rapid engulfment of apoptotic cells is a specialized innate immune response used by organisms to remove apoptotic cells. In mammals, several receptors that recognize apoptotic cells have been identified; molecules that transduce signals from these receptors to downstream cytoskeleton molecules have not been found, however [1–3]. Our previous analysis of the engulfment gene ced-6 in Caenorhabditis elegans has suggested that CED-6 is an adaptor protein that participates in a signal transduction pathway that mediates the specific recognition and engulfment of apoptotic cells [1]. Here, we describe our isolation and characterization of a human cDNA encoding a protein, hCED-6, with strong sequence similarity to C. elegans CED-6. As is the case with the worm protein, hCED-6 contains a phosphotyrosine-binding (PTB) domain and potential Src-homology domain 3 (SH3) binding sites. Both CED-6 and hCED-6 contain a predicted coiled-coil domain in the middle region. The hCED-6 protein lacks the extended carboxyl terminus found in worm CED-6; this carboxy-terminal extension appears not to be essential for CED-6 function in C. elegans, however. Overexpression of hCED-6 rescues the engulfment defect of ced-6 mutants in C. elegans significantly, suggesting that hCED-6 is a functional homologue of C. elegans CED-6. Human ced-6 is expressed widely in most human tissues. Thus, CED-6, and the CED-6 signal transduction pathway, might be conserved from C. elegans to humans and are present in most, if not all, human tissues
Soluble components of the flagellar export apparatus, FliI, FliJ, and FliH, do not deliver flagellin, the major filament protein, from the cytosol to the export gate

AbstractFlagella, the locomotion organelles of bacteria, extend from the cytoplasm to the cell exterior. External flagellar proteins are synthesized in the cytoplasm and exported by the flagellar type III secretion system. Soluble components of the flagellar export apparatus, FliI, FliH, and FliJ, have been implicated to carry late export substrates in complex with their cognate chaperones from the cytoplasm to the export gate. The importance of the soluble components in the delivery of the three minor late substrates FlgK, FlgL (hook–filament junction) and FliD (filament-cap) has been convincingly demonstrated, but their role in the transport of the major filament component flagellin (FliC) is still unclear.We have used continuous ATPase activity measurements and quartz crystal microbalance (QCM) studies to characterize interactions between the soluble export components and flagellin or the FliC:FliS substrate–chaperone complex. As controls, interactions between soluble export component pairs were characterized providing Kd values. FliC or FliC:FliS did not influence the ATPase activity of FliI alone or in complex with FliH and/or FliJ suggesting lack of interaction in solution. Immobilized FliI, FliH, or FliJ did not interact with FliC or FliC:FliS detected by QCM. The lack of interaction in the fluid phase between FliC or FliC:FliS and the soluble export components, in particular with the ATPase FliI, suggests that cells use different mechanisms for the export of late minor substrates, and the major substrate, FliC. It seems that the abundantly produced flagellin does not require the assistance of the soluble export components to efficiently reach the export gate
Energy-efficient mobile web in a bundle

AbstractThe mobile Internet that was a huge hype ten years ago is finally here. We have a wealth of mobile devices that allow us to enjoy and consume Internet content from any number of web sites and services. With faster processors and radio links, our use of the Internet and the traffic mobile users generate grows at a tremendous pace. In this development, we still have a huge challenge to tackle: energy efficiency. When ten years ago one would recharge his personal mobile device once a week, we now do that daily; Smart phones today are not able to carry enough energy to allow us several days of usage time. The focus on this paper is to present and analyse one solution to help us in our daily lives. We implement and study a scheme where web content, a page, is delivered as a whole to a mobile device, instead of sending each individual object of the page separately. Combined with RRC state based header compression and selective content compression, our proposal allows the radio to keep in low power state for longer durations, and as a consequence brings huge energy savings. Download times also decrease, thus bringing increased Quality of Experience
Multifocal Epithelial Tumors and Field Cancerization from Loss of Mesenchymal CSL Signaling

SummaryIt is currently unclear whether tissue changes surrounding multifocal epithelial tumors are a cause or consequence of cancer. Here, we provide evidence that loss of mesenchymal Notch/CSL signaling causes tissue alterations, including stromal atrophy and inflammation, which precede and are potent triggers for epithelial tumors. Mice carrying a mesenchymal-specific deletion of CSL/RBP-Jκ, a key Notch effector, exhibit spontaneous multifocal keratinocyte tumors that develop after dermal atrophy and inflammation. CSL-deficient dermal fibroblasts promote increased tumor cell proliferation through upregulation of c-Jun and c-Fos expression and consequently higher levels of diffusible growth factors, inflammatory cytokines, and matrix-remodeling enzymes. In human skin samples, stromal fields adjacent to multifocal premalignant actinic keratosis lesions exhibit decreased Notch/CSL signaling and associated molecular changes. Importantly, these changes in gene expression are also induced by UVA, a known environmental cause of cutaneous field cancerization and skin cancer
Measured Internal Temperatures in UK Homes – A Time Series Analysis And Modelling Approach

AbstractThis paper presents an analysis of internal air temperatures measured hourly in the living rooms of 230 domestic buildings in the city of Leicester, UK. Time series analysis is used to identify the mechanisms that shape room temperatures, during the summertime period of July and August, in rooms that are neither mechanically heated nor cooled, and to develop empirical models of room temperatures for use in predicting future temperatures based on past measured values and on future weather conditions. Such models can enable overheating risk alerts for homeowners and public authorities to be more accurately estimated and targeted
When is a smash product semiprime? A partial answer

AbstractIt is an open question whether the smash product of a semisimple Hopf algebra and a semiprime module algebra is semiprime. In this paper we show that the smash product of a commutative semiprime module algebra over a semisimple cosemisimple Hopf algebra is semiprime. In particular we show that the central H-invariant elements of the Martindale ring of quotients of a module algebra form a von Neumann regular and self-injective ring whenever A is semiprime. For a semiprime Goldie PI H-module algebra A with central invariants we show that A#H is semiprime if and only if the H-action can be extended to the classical ring of quotients of A if and only if every non-trivial H-stable ideal of A contains a non-zero H-invariant element. In the last section we show that the class of strongly semisimple Hopf algebras is closed under taking Drinfeld twists. Applying some recent results of Etingof and Gelaki we conclude that every semisimple cosemisimple triangular Hopf algebra over a field is strongly semisimple
Updated BBN bounds on the cosmological lepton asymmetry for non-zero θ13

AbstractWe discuss the bounds on the cosmological lepton number from Big Bang Nucleosynthesis (BBN), in light of recent evidences for a large value of the neutrino mixing angle θ13, sin2θ13≳0.01 at 2σ. The largest asymmetries for electron and μ, τ neutrinos compatible with He4 and H2 primordial yields are computed versus the neutrino mass hierarchy and mixing angles. The flavour oscillation dynamics is traced till the beginning of BBN and neutrino distributions after decoupling are numerically computed. The latter contains in general, non-thermal distortion due to the onset of flavour oscillations driven by solar squared mass difference in the temperature range where neutrino scatterings become inefficient to enforce thermodynamical equilibrium. Depending on the value of θ13, this translates into a larger value for the effective number of neutrinos, Neff. Upper bounds on this parameter are discussed for both neutrino mass hierarchies. Values for Neff which are large enough to be detectable by the Planck experiment are found only for the (presently disfavoured) range sin2θ13⩽0.01
Using mental-modelling to explore how irrigators in the Murray–Darling Basin make water-use decisions

AbstractStudy regionWater stress and over-allocation are at the forefront of water management and policy challenges in Australia, especially in the Murray–Darling Basin (MDB). Because irrigated agriculture is a major social and economic component of the MDB, farmer decision-making plays a major role in water sustainability in the region.Study focusThis study used a fuzzy cognitive mapping methodology, ‘mental modeling’, to understand the perceived constraints of irrigator water-use decisions in the MDB, for two different types of irrigation: permanent and annual crops. The approach elicits and documents irrigator insights into the complex and networked nature of irrigation water use decisions in relation to farm-based dynamics.New hydrological insights for the regionResults suggest support for greater local and irrigator involvement in water management decisions. Many, if not most, of the irrigators understood the need for, or at least the inevitability of, governmental policies and regulations. However, a lack of accountability, predictability, and transparency has added to the uncertainty in farm-based water decision-making. Irrigators supported the concept of environmental sustainability, although they might not always agree with how the concept is implemented. The mental modelling approach facilitated knowledge sharing among stakeholders and can be used to identify common goals. Future research utilizing the mental modelling approach may encourage co-management and knowledge partnerships between irrigators, water managers and government officials
Gauge-Higgs unification in the left–right model

AbstractWe construct a supersymmetric left–right model in four dimension with gauge-Higgs unification starting from a SU(3)c×SU(4)w×U(1)B−L gauge symmetry in five dimension. The model has several interesting features, such as, the CKM mixings in the quark sector are naturally small while for the neutrino sector it is not, light neutrino masses can be generated via the seesaw mechanism in the usual way, and the model has a U(1)R symmetry which naturally forbid dimension five proton decay operators. We also discuss the grand unification of our model in SO(12) in five dimensions
Search for three-jet resonances in pp collisions at s=7TeV

AbstractResults are reported from a search for the production of three-jet resonances in pp collisions at a center-of-mass energy s=7 TeV. The study uses the data sample collected by the CMS experiment at the LHC in 2011, corresponding to an integrated luminosity of 5.0 fb−1. Events with high jet multiplicity and a large scalar sum of jet transverse momenta are analyzed for the presence of resonances in the three-jet invariant mass spectrum. No evidence for a narrow resonance is found in the data, and limits are set on the cross section for gluino pair production in an R-parity-violating supersymmetry model, for gluino masses greater than 280 GeV. Assuming a branching fraction for gluino decay into three jets of 100%, gluino masses below 460 GeV are excluded at 95% confidence level. These results significantly extend the range of previous limits
Insights into the behaviour of S, F, and Cl at Santiaguito Volcano, Guatemala, from apatite and glass

AbstractThe mineral apatite can incorporate all of the major magmatic volatile species into its structure. Where melt inclusions are not available, magmatic apatite may therefore represent an opportunity to quantify volatile concentrations in the pre-eruptive melt. We analysed apatites and matrix glasses from andesites and dacites erupted from Santiaguito Volcano, Guatemala, between the 1920s and 2002. X-ray mapping shows complex zoning of sulphur in the apatite grains, but typically with sulphur-rich cores and sulphur-poor rims. Apatite microphenocrysts are enriched in F and depleted in Cl relative to inclusions. Matrix glasses are dacite to rhyolite and contain low F but up to 2400ppm Cl. Overall, the data are consistent with progressive depletion of Cl in the most evolved melts due to crystallisation and degassing. In the absence of pristine melt inclusions, we used apatite, together with published partitioning data, to reconstruct the likely volatile contents of the pre-eruptive melt, and hence estimate long-term average gas emissions of SO2, HF and HCl for the ongoing eruption. The data indicate time-averaged SO2 emissions of up to 157 tonnes/day, HCl of 74–1382 tonnes/day and up to 196 tonnes/day HF. Apatite may provide a useful measure of long-term volatile emissions at volcanoes where direct emissions measurements are unavailable, or for comparison with intermittent gas sampling methods. However, significant uncertainty remains regarding volatile distribution coefficients for apatite, and their variations with temperature and pressure
Addendum to: “The SNO solar neutrino data, neutrinoless double beta-decay and neutrino mass spectrum” [Phys. Lett. B 544 (2002) 239]

AbstractWe update our earlier study [Phys. Lett. B 544 (2002) 239], which was inspired by the 2002 SNO data, on the implications of the results of the solar neutrino experiments for the predictions of the effective Majorana mass in neutrinoless double beta-decay, |〈m〉|. We obtain predictions for |〈m〉| using the values of the neutrino oscillation parameters, obtained in the analyzes of the presently available solar neutrino data, including the just published data from the salt phase of the SNO experiment, the atmospheric neutrino and CHOOZ data and the first data from the KamLAND experiment. The main conclusion reached in the previous study [Phys. Lett. B 544 (2002) 239] of the existence of significant lower bounds on |〈m〉| in the cases of neutrino mass spectrum of inverted hierarchical (IH) and quasi-degenerate (QD) type is strongly reinforced by fact that combined solar neutrino data (i) exclude the possibility of cos2θ⊙=0 at more than 5 s.d., (ii) determine as a best fit value cos2θ⊙=0.40, and (iii) imply at 95% C.L. that cos2θ⊙≳0.22, θ⊙ being the solar neutrino mixing angle. For the IH and QD spectra we get using, e.g., the 90% C.L. allowed ranges of values of the oscillation parameters, |〈m〉|≳0.010 eV and |〈m〉|≳0.043 eV, respectively. We also comment on the possibility to get information on the neutrino mass spectrum and on the CP-violation in the lepton sector due to Majorana CP-violating phases
Determination of the Gamow–Teller quenching factor from charge exchange reactions on 90Zr

AbstractDouble differential cross sections between 0°–12° were measured for the 90Zr(n, p) reaction at 293 MeV over a wide excitation energy range of 0–70 MeV. A multipole decomposition technique was applied to the present data as well as the previously obtained 90Zr(p, n) data to extract the Gamow–Teller (GT) component from the continuum. The GT quenching factor Q was derived by using the obtained total GT strengths. The result is Q=0.88±0.06, not including an overall normalization uncertainty in the GT unit cross section of 16%
A national coastal erosion susceptibility model for Scotland

AbstractThe upland nature of the Scottish landscape means that much of the social and economic activity has a coastal bias. The importance of the coast is further highlighted by the wide range of ecosystem services that coastal habitats provide. It follows that the threat posed by coastal erosion and flooding has the potential to have a substantial effect on the socioeconomic activity of the whole country. Currently, the knowledge base of coastal erosion is poor and this serves to hinder the current and future management of the coast. To address this knowledge gap, two interrelated models have been developed and are presented here: the Underlying Physical Susceptibility Model (UPSM) and the Coastal Erosion Susceptibility Model (CESM). The UPSM is generated within a GIS at a 50 m2 raster of national coverage, using data relating to ground elevation, rockhead elevation, wave exposure and proximity to the open coast. The CESM moderates the outputs of the UPSM to include the effects of sediment supply and coastal defence data. When validated against locations in Scotland that are currently experiencing coastal erosion, the CESM successfully identifies these areas as having high susceptibility. This allows the UPSM and CESM to be used as tools to identify assets inherently exposed to coastal erosion, areas where coastal erosion may exacerbate coastal flooding, and areas are inherently resilient to erosion, thus allow more efficient and effective management of the Scottish coast
Limited microstructural and connectivity deficits despite subcortical volume reductions in school-aged children born preterm with very low birth weight

AbstractPreterm birth and very low birth weight (VLBW, ≤1500g) are worldwide problems that burden survivors with lifelong cognitive, psychological, and physical challenges. In this multimodal structural magnetic resonance imaging (MRI) and diffusion MRI (dMRI) study, we investigated differences in subcortical brain volumes and white matter tract properties in children born preterm with VLBW compared to term-born controls (mean age=8years). Subcortical brain structure volumes and cortical thickness estimates were obtained, and fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD) were generated for 18 white matter tracts. We also assessed structural relationships between white matter tracts and cortical thickness of the tract endpoints. Compared to controls, the VLBW group had reduced volumes of thalamus, globus pallidus, corpus callosum, cerebral white matter, ventral diencephalon, and brain stem, while the ventricular system was larger in VLBW subjects, after controlling for age, sex, IQ, and estimated total intracranial volume. For the dMRI parameters, group differences were not significant at the whole-tract level, though pointwise analysis found shorter segments affected in forceps minor and left superior longitudinal fasciculus – temporal bundle. IQ did not correlate with subcortical volumes or dMRI measures in the VLBW group. While the deviations in subcortical volumes were substantial, there were few differences in dMRI measures between the two groups, which may reflect the influence of advances in perinatal care on white matter development