pinecone/core-2020-05-10-deduplication huggingface dataset:
Model and simulation of a solar kiln with energy storage

A solar kiln with energy storage can be used for continuous drying. This kiln consisted of several units which were modeled to simulate it in operation. A model was proposed for each unit, and another based on laboratory tests for drying a wooden board by passing air across. These models were combined to produce a global model. Simulation results were then analyzed and showed that the use of storage was justified to reduce drying time. Moreover, with the judicious use of storage and air renewal, drying schedules could be produced for a better quality of dried wood
Sources of hepatic glucose production by 2H2O ingestion and Bayesian analysis of 2H glucuronide enrichment

The contribution of gluconeogenesis to hepatic glucose production (GP) was quantified after 2H2O ingestion by Bayesian analysis of the position 2 and 5 2H-NMR signals (H2 and H5) of monoacetone glucose (MAG) derived from urinary acetaminophen glucuronide. Six controls and 10 kidney transplant (KTx) patients with cyclosporine A (CsA) immunosuppressant therapy were studied. Seven KTx patients were lean and euglycemic (BMI = 24.3 ± 1.0 kg/m2; fasting glucose = 4.7 ± 0.1 mM) while three were obese and hyperglycemic (BMI = 30.5 ± 0.7 kg/m2; fasting glucose = 7.1 ± 0.5 mM). For the 16 spectra analyzed, the mean coefficient of variation for the gluconeogenesis contribution was 10% ± 5%. This uncertainty was associated with a mean signal-to-noise ratio (SNR) of 79:1 and 45:1 for the MAG H2 and H5 signals, respectively. For control subjects, gluconeogenesis contributed 54% ± 7% of GP as determined by the mean and standard deviation (SD) of individual Bayesian analyses. For the lean/normoglycemic KTx subjects, the gluconeogenic contribution to GP was 62% ± 7% (P = 0.06 vs. controls), while hyperglycemic/obese KTx patients had a gluconeogenic contribution of 68% ± 3% (P < 0.005 vs. controls). These data suggest that in KTx patients, an increased gluconeogenic contribution to GP is strongly associated with obesity and hyperglycemia. Magn Reson Med 60:517-523, 2008. © 2008 Wiley-Liss, Inc.http://dx.doi.org/10.1002/mrm.2168
The Case for Regularity in Mechanistic Causal Explanation

How regular do mechanisms need to be, in order to count as mechanisms? This paper addresses two arguments for dropping the requirement of regularity from the definition of a mechanism, one motivated by examples from the sciences and the other motivated by metaphysical considerations regarding causation. I defend a broad- ened regularity requirement on mechanisms that takes the form of a taxonomy of kinds of regularity that mechanisms may exhibit. This taxonomy allows precise explication of the degree and location of regular operation within a mechanism, and highlights the role that various kinds of regularity play in scientific explanation. I defend this reg- ularity requirement in terms of regularity’s role in individuating mechanisms against a background of other causal processes, and by prioritizing mechanisms’ ability to serve as a model of scientific explanation, rather than as a metaphysical account of causation. It is because mechanisms are regular, in the expanded sense described here, that they are capable of supporting the kinds of generalizations that figure prominently in scientific explanations
Legal Ontologies for the spanish e-Government

The Electronic Government is a new field of applications for the semantic web where ontologies are becoming an important research technology. The e-Government faces considerable challenges to achieve interoperability given the semantic differences of interpretation, complexity and width of scope. In this paper we present the results obtained in an ongoing project commissioned by the Spanish government that seeks strategies for the e-Government to reduce the problems encountered when delivering services to citizens. We also introduce an e-Government ontology model; within this model a set of legal ontologies are devoted to representing the Real-estate transaction domain used to illustrate this paper
Maximum-likelihood tree estimation using codon substitution models with multiple partitions

Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)Many protein sequences have distinct domains that evolve with different rates, different selective pressures, or may differ in codon bias. Instead of modeling these differences by more and more complex models of molecular evolution, we present a multipartition approach that allows maximum-likelihood phylogeny inference using different codon models at predefined partitions in the data. Partition models can, but do not have to, share free parameters in the estimation process. We test this approach with simulated data as well as in a phylogenetic study of the origin of the leucin-rich repeat regions in the type III effector proteins of the pythopathogenic bacteria Ralstonia solanacearum. Our study does not only show that a simple two-partition model resolves the phylogeny better than a one-partition model but also gives more evidence supporting the hypothesis of lateral gene transfer events between the bacterial pathogens and its eukaryotic hosts
Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations

The novel cardioprotective drug carvedilol was studied by both Raman spectroscopy and ab initio molecular orbital methods (using the density functional theory approach). The spectra, acquired both for the solid samples and DMSO solutions as a function of pH, were assigned in view of the calculated wavenumbers and intensities, and also based on the experimental data obtained for individual compounds which comprise the molecule, namely carbazole and 1,2-dimethoxybenzene. The pH dependence of the Raman pattern of carvedilol was studied, and the pKa value of its secondary amine group was determined (pKa = 8.25) through pH titration experiments. This kind of information is of great significance for the understanding of the biochemical role of carvedilol, which is strongly determined by the acid-base behaviour of the molecule. Copyright © 2002 John Wiley & Sons, Ltd.http://dx.doi.org/10.1002/jrs.91
Informal care and labour force participation among middle-aged women in Spain

Informal care is today the form of support most commonly used in Spain by those who need help in order to carry out basic daily activities. The potential labour opportunity costs incurred by Spanish informal carers have not as yet been quantified. In this paper we use the Spanish subsample of the European Community Household Panel (1994-2001) to estimate an econometric model which we exploit to examine the effects of various types of informal care on labour market outcomes. Our results reveal the existence of non-negligible costs in terms of foregone employment for carers who live with the dependent person and/or provide more than 28 h of care/week. We also find that providing care for more than a year has negative effects on employment. Nonetheless, there seems to be no contemporaneous employment effects associated to either starting or ending an episode of care
Effect of block copolymer nano-reinforcements on the low velocity impact response of sandwich structures

Sandwich composites with fibre reinforced plastic (FRP) facesheets have emerged as a major class of lightweight structural materials in a wide range of engineering fields including aerospace, automotive and marine structures. This is due to attractive mechanical properties such as high specific stiffness and high strength. However, sandwich structures are susceptible to damage caused by impact. The objective of this paper is to evaluate the dynamic response of sandwich composites based on Kevlar fibre reinforced epoxy and Rohacell foam. The improvement in impact performance of these sandwich structures
that can be achieved by the addition of nanoparticles in the resin matrix is investigated. Nanostrength, an acrylate triblock copolymer that self-assembles in the nanometer scale is added to the epoxy matrix.
The effect of the nano-reinforcements on flat sandwich plates under low velocity impact is investigated at different scales. An instrumented drop tower setup is used for the low velocity impact tests of the sandwich plates with neat or nano-reinforced epoxy matrix, at different energies. The macroscopic response of the sandwich structure and the microscopic phenomena involved in dissipating the impact energy are identified and compared for sandwich plates with and without nanoparticles
Factor analysis for metal grade exploration at Pallancata Vein in Peru

Se investiga la distribución espacial de contenidos metálicos analizados sobre testigos de sondeos obtenidos en las campañas de exploración de la Veta Pallancata. Se aplica el análisis factorial a dicha distribución y a los cocientes de los valores metálicos, discriminando los que están correlacionados con la mineralización argentífera y que sirven como guías de exploración para hallar zonas de potenciales reservas por sus gradientes de variación.Abstract:The metal distribution in a vein may show the paths of hydrothermal fluid flow at the time of mineralization. Such information may assist for in-fill drilling. The Pallancata Vein has been intersected by 52 drill holes, whose cores were sampled and analysed, and the results plotted to examine the mineralisation trends. The spatial distribution of the ore is observed from the logAg/logPb ratio distribution. Au is in this case closely related to Ag (electrum and uytenbogaardtite, Ag3AuS2 ). The Au grade shows the same spatial distribution as the Ag grade. The logAg/logPb ratio distribution also suggests possible ore to be expected at deeper locations. Shallow supergene Ag enrichment was also observed
Brief Report: Schema Consistent Misinformation Effects in Eyewitnesses with Autism Spectrum Disorder

A number of studies have demonstrated schema-related misinformation effects in typical individuals, but no research to date has examined this with witnesses with autism spectrum disorder (ASD), despite their impaired ability to generate core elements that define everyday events. After witnessing slides depicting a bank robbery, 16 adults with ASD and 16 matched comparison individuals were exposed to post-event misinformation that was either schema typical or atypical. Consistent with previous work, the comparison group went onto report more schema typical misinformation than atypical misinformation. However, so too did the ASD group, suggesting that individuals with ASD do have understanding of the causal links between events, persons and actions, an important finding from both theoretical and applied perspectives
Experimental and numerical study of laser-assisted machining of Ti6Al4V titanium alloy

Laser-assisted machining combines several experimental parameters such as cutting speed, feed rate, depth of cut, laser power and distance between tool rake face and the laser beam axis. The optimization of these parameters is necessary to ensure the efficiency of assistance and to increase productivity. This paper focuses on the understanding of the physical phenomena during laser-assisted machining, and on optimising this process. This contribution is based on an experimental and a numerical study. The experimentalpart highlights the effects of the laser power as well as the distance between the tool rake face and the axis of the laser beam. As for the numerical part, it was performed on the ABAQUS/Explicit software.
The proposed model improves the understanding of the physical phenomena of chip formation and the cutting force reduction when machining with laser assistance. In addition, this model allows a better optimization of laser and cutting parameters.Numerical findings generally corroborate experimental results and can lead to some other information difficult to catch experimentally.
The main contention in the paper is that the distance between the axis of the laser beam and the tool rake face is the most important parameter that controls the reduction of the cutting force. This cutting force reduction can exceed 50%
Regulatory RNA at the root of animals: dynamic expression of developmental lincRNAs in the calcisponge Sycon ciliatum

Long non-coding RNAs (lncRNAs) play important regulatory roles during animal development, and it has been hypothesized that an RNA-based gene regulation was important for the evolution of developmental complexity in animals. However, most studies of lncRNA gene regulation have been performed using model animal species, and very little is known about this type of gene regulation in non-bilaterians. We have therefore analysed RNA-Seq data derived from a comprehensive set of embryogenesis stages in the calcareous sponge Sycon ciliatum and identified hundreds of developmentally expressed intergenic lncRNAs (lincRNAs) in this species. In situ hybridization of selected lincRNAs revealed dynamic spatial and temporal expression during embryonic development. More than 600 lincRNAs constitute integral parts of differentially expressed gene modules, which also contain known developmental regulatory genes, e.g. transcription factors and signalling molecules. This study provides insights into the non-coding gene repertoire of one of the earliest evolved animal lineages, and suggests that RNA-based gene regulation was likely present in the last common ancestor of animals
Estimation of toxic elements in the samples of different cigarettes and their impact on human health of Irish hypertensive consumers

Background: Cigarette smoking interferes with the metal homeostasis of the human body, which plays a crucial role for maintaining the health. A significant flux of heavy metals, among other toxins, reaches the lungs through smoking. In the present study, the relationship between toxic element (TE) exposure via cigarette smoking and hypertension incidence in population living in Dublin, Ireland is investigated. Methods: The different brands of cigarette (filler tobacco, filter and ash) consumed by the studied population were analyzed for cadmium (Cd), nickel (Ni), and lead (Pb). The concentrations of TEs in biological samples and different components of cigarette were measured by inductively coupled plasma atomic emission spectrophotometer after microwave-assisted acid digestion. The validity and accuracy of the methodology were checked using certified reference materials. Results: The filler tobacco of different branded cigarettes contains Cd, Ni and Pb concentrations in the ranges of 1.73-2.02, 0.715-1.52 and 0378-1.16 pg/cigarette, respectively. The results of this study showed that the mean values of Cd, Ni and Pb were significantly higher in scalp hair and blood samples of hypertensive patients in relation to healthy controls, while the difference was significant in the case of smoker patients (p < 0.001). The levels of all the three TEs were 2-3 folds higher in scalp hair and blood samples of non-hypertensive smoker subjects as compared to nonsmoker controls. Conclusion: The high exposure of toxic metals as a result of cigarette smoking may be synergistic with risk factors associated with hypertension
Lepton parameters in the see-saw model extended by one extra Higgs doublet

We investigate the radiative generation of lepton masses and mixing angles in the Standard Model extended by one right-handed neutrino and one extra Higgs doublet. We assume approximate rank-1 Yukawa couplings at a high energy scale and we calculate the one loop corrected charged lepton and neutrino mass matrices at the low energy scale. We find that quantum effects generate, for typical high energy parameters, a hierarchy between the muon and the tau mass, a hierarchy between the solar and the atmospheric mass splittings, and a pattern of leptonic mixing angles in qualitative agreement with experiments
Approximability of scheduling problems with\ud
resource consuming jobs

The paper presents new approximability results for single machine scheduling problems with jobs requiring\ud
some non-renewable resources (like raw materials, energy, or money) beside the machine. Each resource has\ud
an initial stock and additional supplies over time. A feasible schedule specifies a starting time for each job\ud
such that no two jobs overlap in time, and when a job is started, enough resources are available to cover\ud
its requirements. The goal is to find a feasible schedule of minimum makespan. This problem is strongly\ud
NP-hard.\ud
Recently, the authors of this paper have proposed a PTAS for the special case with a single non-renewable\ud
resource and with a constant number of supply dates, as well as an FPTAS for the special case with two\ud
supply dates and one resource only. In this paper we prove APX-hardness of the problem when the number\ud
of resources is part of the input, and new polynomial time approximation schemes are devised for some\ud
variants, including (1) job release dates, and more than one, but constant number of resources and resource\ud
supply dates, and (2) only one resource, arbitrary number of supply dates and job release dates, but with\ud
resource requirements proportional to job processing times
Improved high-speed de-excitation system for brushless synchronous machines tested on a 20 MVA hydro-generator

Synchronous machines with brushless excitation have the disadvantage that the field winding is not accessible\ud
for the de-excitation of the machine. This means that, despite the proper operation of the protection system, the slow de-excitation time constant may produce severe damage in the event of an internal short circuit. A high-speed de-excitation system for these machines was developed, and this study presents the continuation of a previously published study. This study presents the design by computer simulation and the results of the first commissioning of this de-excitation system in a commercial 20 MVA hydro-generator. The de-excitation is achieved by inserting resistance in the field circuit, obtaining a dynamic response similar to that achieved in machines with static excitation. In this case, a non-linear discharge resistor\ud
was used, making the dynamic response even better
INTERACTION OF 20-100 MeV/u HEAVY IONS WITH COLD MATTER

The stopping powers of 12 solids and 10 gases and the associated energy loss straggling have been measured at GANIL for 16-17O, 40Ar,40Ca, 84-86Kr, 100Mo and 129-132Xe ions in the energy domain 24 to 35 MeV/u. After a brief description of the experimental method, the set of data are presented and discussed. As far as stopping powers are concerned, a scaling law in Z2 relative to the 4He stopping powers at the same velocity becomes applicable when the projectile tends to be fully stripped. At the same time, the solid-gas effect, observed at low energy, vanishes. The energy loss straggling is compared to that deduced from Bohr model and some of its refinements. The theoretical value appears to be too small, by a factor 2, when the projectile is fully stripped. For partially stripped ions, the charge exchange straggling might explain the experimental observation
QCD studies with the hadronic final states at HERA

Available online Jan. 24, 2006New and complementary results with respect to the inclusive proton structure function have been obtained in the HERA new kinematical domain by studying extensively the previous termhadronic finalnext term states by both H1 and ZEUS collaborations. Shown here are the observation of hard partonic scattering in photoproduction and diffractive interactions, the comparison of hadron production in the central rapidity region between photoproduction and deep inelastic scattering, the precise determination of α3 over a large energy range in a single experiement, and the evidence of the hard diffractive scattering
Kawasaki disease in adults: observations in France and literature review Short title: Kawasaki disease in adults in France

International audienceObjective Kawasaki disease (KD) is a vasculitis that mostly occurs in young children and rarely in adults. We analyzed the characteristics of adult-onset KD (AKD) in France. Methods We collected retrospective and prospective data for patients with a diagnosis of KD occurring after the age of 18 years. Cases were obtained via various French medical networks and identified from the international literature. Results We included 43 patients of AKD at 26 institution from 1992 to 2015, with mean (SD) age 30 (11) years (range 18–68) and sex ratio (M/F) 1.2; 34 patients met the American Heart Association criteria and 9 were incomplete AKD. The median time to diagnosis was 13 days (interquartile range 8–21). The main symptoms were fever (100%), exanthema (98%), changes in the extremities (91%), conjunctivitis (77%), oral cavity changes (89%), cervical adenitis (55%) and cardiac abnormalities (45%). Overall, 35% of patients showed large-vessel vasculitis: coronary vasculitis (26%) and coronary aneurysm (19%). Treatment was mostly intravenous immunoglobulins (79%) and aspirin (81%). Four patients showed myocardial infarction due to coronary vasculitis, but none were treated with IVIg because of late diagnosis. After a median follow-up of 5 months (range 1–117), persistent aneurysm was noted in 9% of cases. Damage was significantly lower with early treatment than late or no treatment (p = 0.01). Conclusion Given the high frequency of cardiac involvement and complications in this series of AKD, diagnosis and treatment should not be delayed, and early IVIg treatment seems to improve the outcom
Upper Pleistocene uplifted shorelines as tracers of (local rather than global) subduction dynamics

International audiencePast studies have shown that high coastal uplift rates are restricted to active areas, especially in a subduction context. The origin of coastal uplift in subduction zones, however, has not yet been globally investigated. Quaternary shorelines correlated to the last interglacial maximum (MIS 5e) were defined as a global tectonic benchmark (Pedoja et al. (2011)). In order to investigate the relationships between the vertical motion and the subduction dynamic parameters, we cross-linked this coastal uplift database with the "geodynamical" databases from Heuret (2005), Conrad and Husson (2009) and Müller et al. (2008). Our statistical study shows that: [1] the most intuitive parameters one can think responsible for coastal uplift (e.g., subduction obliquity, trench motion, oceanic crust age, interplate friction and force, convergence variation, dynamic topography, overriding and subducted plate velocity) are not related with the uplift (and its magnitude); [2] the only intuitive parameter is the distance to the trench which shows in specific areas a decrease from the trench up to a distance of ~300 km; [3] the slab dip (especially the deep slab dip), the position along the trench and the overriding plate tectonic regime are correlated with the coastal uplift, probably reflecting transient changes in subduction parameters. Finally we conclude that the first order parameter explaining coastal uplift is small-scale heterogeneities of the subducting plate, as for instance subducting aseismic ridges. The influence of large-scale geodynamic setting of subduction zones is secondary