pinecone/core-2020-05-10-deduplication huggingface dataset:
An unfitted Nitsche method for incompressible fluid-structure interaction using overlapping meshes

International audienceWe consider the extension of the Nitsche method to the case of fluid-structure interaction problems on unfitted meshes. We give a stability analysis for the space semi-discretized problem and show how this estimate may be used to derive optimal error estimates for smooth solutions, irrespectively of the mesh/interface intersection. We also discuss different strategies for the time discretization, using either fully implicit or explicit coupling (loosely coupled) schemes. Some numerical examples illustrate the theoretical discussion
Trapped or spurred by the home region? The effects of potential social capital on involvement in foreign markets for goods and technology

OPEN ACCESSDrawing on social capital theory and the international business literature, we
argue that domestic geography, in terms of localized potential social capital,
facilitates individual firms’ awareness of business opportunities, including
knowledge related to involvement in the foreign markets for goods and tech-
nology, thereby enhancing firms’ involvement in those foreign markets. When
potential social capital reaches a certain threshold, it may work to trap firms
into operating only within their home regions, thus reducing involvement in
foreign markets. We conjecture that firms’ research and development invest-
ment moderates the relationship between potential social capital and degree of
involvement in foreign markets, but given the very different properties of the
two markets, with different signs for each market: a positive moderation effect
for the markets for goods, and a negative effect for the markets for technology.
We find empirical support for our arguments based on a representative sample
of around 2000 Italian firms
Asymptotic behaviour of zeros of exceptional Jacobi and Laguerre
  polynomials

The location and asymptotic behaviour for large n of the zeros of exceptional
Jacobi and Laguerre polynomials are discussed. The zeros of exceptional
polynomials fall into two classes: the regular zeros, which lie in the interval
of orthogonality and the exceptional zeros, which lie outside that interval. We
show that the regular zeros have two interlacing properties: one is the natural
interlacing between consecutive polynomials as a consequence of their
Sturm-Liouville character, while the other one shows interlacing between the
zeros of exceptional and classical polynomials. A generalization of the
classical Heine-Mehler formula is provided for the exceptional polynomials,
which allows to derive the asymptotic behaviour of their regular zeros. We also
describe the location and the asymptotic behaviour of the exceptional zeros,
which converge for large n to fixed values.Comment: 19 pages, 3 figures, typed in AMS-LaTe
High temperature oxidation of a Cu-Ni – based cermet: kinetic and microstructural study

International audienceThe oxidation of a cermet composed of nickel ferrite (NixFe3-xO4), nickel oxide (NiyFe1-yO) and Ni-Cu alloy (CuzNi1-z) (with x=0.8, y=0.84 and z=0.44) has been studied by thermogravimetry, at 960°C, under controlled oxygen partial pressure. The rate of oxidation increases with the oxygen partial pressure up to 5.1 103 Pa, then it becomes independent of the oxygen pressure. This is due to the presence of the two copper oxides, CuO and Cu2O, above this oxygen pressure. SEM observation of oxidized samples has shown that the oxidation mechanism involves both external and internal oxidation
AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration.
 : 
AMPKα1 regulates macrophage skewing

International audienceMacrophages control the resolution of inflammation through the transition from a proinflammatory (M1) to an anti-inflammatory (M2) phenotype. Here, we present evidence for a role of AMPKα1, a master regulator of energy homeostasis, in macrophage skewing that occurs during skeletal muscle regeneration. Muscle regeneration was impaired in AMPKα1(-/-) mice. In vivo loss-of-function (LysM-Cre;AMPKα1(fl/fl) mouse) and rescue (bone marrow transplantation) experiments showed that macrophagic AMPKα1 was required for muscle regeneration. Cell-based experiments revealed that AMPKα1(-/-) macrophages did not fully acquire the phenotype or the functions of M2 cells. In vivo, AMPKα1(-/-) leukocytes did not acquire the expression of M2 markers during muscle regeneration. Skewing from M1 toward M2 phenotype upon phagocytosis of necrotic and apoptotic cells was impaired in AMPKα1(-/-) macrophages and when AMPK activation was prevented by the inhibition of its upstream activator, CaMKKβ. In conclusion, AMPKα1 is crucial for phagocytosis-induced macrophage skewing from a pro- to anti-inflammatory phenotype at the time of resolution of inflammation
The discourses of marketing and development: towards 'critical transformative marketing research'

Cataloged from PDF version of article.In order to understand the connection between development,
marketing and transformative consumer research (TCR), with its attendant
interest in promoting human well-being, this article begins by charting the
links between US ‘exceptionalism’, ‘Manifest Destiny’ and modernisation
theory, demonstrating the confluence of US perspectives and experiences in
articulations and understandings of the contributions of marketing practice and
consumer research to society. Our narrative subsequently engages with the rise
of social marketing (1960s-) and finally TCR (2006-). We move beyond calls for
an appreciation of paradigm plurality to encourage TCR scholars to adopt a
multiple paradigmatic approach as part of a three-pronged strategy that
encompasses an initial ‘provisional moral agnosticism’. As part of this stance,
we argue that scholars should value the insights provided by multiple
paradigms, turning each paradigmatic lens sequentially on to the issue of the
relationship between marketing, development and consumer well-being. After
having scrutinised these issues using multiple perspectives, scholars can then
decide whether to pursue TCR-led activism. The final strategy that we identify is
termed ‘critical intolerance’
Use of ATP bioluminescence for assessing the cleanliness of hospital surfaces: A review of the published literature (1990-2012)

Hospital cleanliness tends to be considered by patients and the public as an important indicator of the general quality of healthcare. Tests for detecting the presence of adenosine triphosphate (ATP) as a proxy of microbial contamination are increasing in popularity, and several studies have been conducted on this topic in the last few decades. The aim of the present study was to review the published literature on this topic and summarize and discuss the available results. The review focused on relevant English-language articles that were identified through searches of two databases [PubMed and Scopus (1990-2012)] by using the keywords "ATP", "bioluminescence", "hospital", and "surfaces". Twelve articles were included and analyzed. ATP measurements showed a wide variation, with values ranging from 0 to >500,000 relative light units (RLU)/s before cleaning and from 3 to 500,000. RLU/s after cleaning. ATP benchmarks used by authors ranged from 100 to 500. RLU/s. The percentage of surfaces exceeding the chosen cut-off limit showed a failure rate varying from 21.2% to 93.1% before cleaning and from 5.3% to 96.5% after cleaning. Although the use of ATP bioluminescence can be considered a quick and objective method for assessing hospital cleanliness, it appears to be still poorly standardized at both the national and international level. © 2013 King Saud Bin Abdulaziz University for Health Sciences
Cognitive and affective assessment in day care versus institutionalized elderly patients: a 1-year longitudinal study

[Abstract] Purpose: Cognitive decline and depression are two common mental health problems that may create a need for long-term care among the elderly. In the last decade, the percentage of older adults who receive health care in nursing homes, day care centers, or home support services has increased in Europe. The objectives of this descriptive and nonrandomized longitudinal study were to evaluate and to compare the cognitive and affective evolution of day care versus institutionalized older patients through a 1-year period, and to assess the presence of cognitive and affective impairment as a function of the care setting.
Patients and methods: Ninety-four patients were assessed at baseline, and 63 (67.0%) were reassessed 1 year later. Neuropsychological assessment included measures of cognitive performance (general cognitive status, visuospatial, and language abilities) and affective status (depressive symptoms).
Results: Our findings indicated that the majority of the participants (day care and institutionalized patients) had mild–moderate cognitive impairment at baseline, which significantly increased in both groups after 1-year follow-up. However, the rate of change in global cognitive function did not significantly differ between groups over time. Regarding language abilities, naming function maintained among day care patients in comparison with institutionalized patients, who showed worse performance at follow-up. As regards to affective status, results revealed that institutionalized patients had a significant reduction in depressive symptoms at follow-up, when compared to day care patients. Results also highlight the high frequency of cognitive impairment and depressive symptoms regardless of the care setting.
Conclusion: Our findings revealed a similar global cognitive decline rate between patients receiving day care services and those residing in a nursing home at the 1-year follow-up, and slightly different trajectories in other outcomes such as naming function and depressive symptoms
8.4 GHz VLBI observations of SN 2004et in NGC 6946

We report on 8.4 GHz very-long-baseline-interferometry (VLBI) observations of the type II-P supernova SN2004et in the spiral galaxy NGC 6946, made on 20 February 2005 (151 days after explosion). The Very Large Array (VLA) flux density was 1.23 ± 0.07 mJy, corresponding to an isotropic luminosity at 8.4 GHz of (4.45 ± 0.3) × 1025 erg s^−1 Hz^−1 and a brightness temperature of (1.3 ± 0.3) × 108 K. We also provide an improved source position, accurate to about 0.5 mas in each coordinate. The VLBI image shows a clear asymmetry. From model fitting of the size of the radio emission, we estimate a minimum expansion velocity of 15 700 ± 2000 km s^−1. This velocity is more than twice the expected mean expansion velocity estimated from a synchrotron self-absorbed emission model, thus suggesting that synchrotron self-absorption is not relevant for this supernova. With the benefit of an optical spectrum obtained 12 days after explosion, we favor an emission model which consists of two hot spots on an underlying expanding shell of width comparable to that of SN1993J.Marti Vidal, Ivan, I.Marti-Vidal@uv.es ; Marcaide Osoro, Juan Maria, J.M.Marcaide@uv.es ; Guirado Puerta, Jose Carlos, Jose.C.Guirado@uv.es ; Perez Torres, Miguel Angel, M.Angel.Perez@uv.e
GEANT4 simulation of the neutron background of the C6D6 set-up for capture studies at n_TOF

The neutron sensitivity of the C6D6 detector setup used at n_TOF facility for capture measurements has been studied by means of detailed GEANT4 simulations. A realistic software replica of the entire n_TOF experimental hall, including the neutron beam line, sample, detector supports and the walls of the experimental area has been implemented in the simulations. The simulations have been analyzed in the same manner as experimental data, in particular by applying the Pulse Height Weighting Technique. The simulations have been validated against a measurement of the neutron background performed with a natC sample, showing an excellent agreement above 1 keV. At lower energies, an additional component in the measured natC yield has been discovered, which prevents the use of natC data for neutron background estimates at neutron energies below a few hundred eV. The origin and time structure of the neutron background have been derived from the simulations. Examples of the neutron background for two different samples are demonstrating the important role of accurate simulations of the neutron background in capture cross-section measurements
Optical absorption and thermoluminescence studies in 100 MeV swift heavy ion irradiated CaF2 crystals

Pure and Ytterbium (Yb) doped Calcium fluoride (CaF2) single crystals were irradiated with 100 MeV Ni7+ ions for fluences in the range 5 x 10(11)-2.5 x 10(13) ions cm(-2). The irradiated crystals were characterized by Optical absorption (OA) and Thermoluminescence (TL) techniques. The OA spectra of ion irradiated pure CaF2 crystals showed a broad absorption with peak at similar to 556 nm and a weak one at similar to 220 nm, whereas the Yb doped crystals showed two strong absorption bands at similar to 300 and 550 nm. From the study of OA spectra, the defect centers responsible for the absorption were identified. TL measurements of Ni7+ ion irradiated pure CaF2 samples indicated a strong TL glow with peak at similar to 510 K. However, the Yb doped crystals showed two TL glows at similar to 406 and 496 K. The OA and TL intensity were found to increase with increase of ion fluence upto 1 x 10(13) ions cm(-2) and thereafter it decreased with further increase of fluence. The results obtained are discussed in detail. (C) 2010 Elsevier B.V. All rights reserved.\ud
Keyword
Vibrational relaxation as the driving force for wavelength conversion in the peridinin-chlorophyll a-protein

Abstract We present a computationally derived energy transfer model for the peridinin-chlorophyll a-protein (PCP), which invokes vibrational relaxation in the two lowest singlet excited states rather than internal conversion between them. The model allows an understanding of the photoinduced processes without assuming further electronic states or a dependence of the 2Ag state character on the vibrational sub-state. We report molecular dynamics simulations (CHARMM22 force field) and quantum mechanics/molecular mechanics (QM/MM) calculations on PCP. In the latter, the QM region containing a single peridinin (Per) chromophore or a Per-Chl a (chlorophyll a) pair is treated by density functional theory (DFT, CAM-B3LYP) for geometries and by DFT-based multireference configuration interaction (DFT/MRCI) for excitation energies. The calculations show that Per has a bright, green light absorbing 2Ag state, in addition to the blue light absorbing 1Bu state found in other carotenoids. Both states undergo a strong energy lowering upon relaxation, leading to emission in the red, while absorbing in the blue or green. The orientation of their transition dipole moments indicates that both states are capable of excited-state energy transfer to Chl a, without preference for either 1Bu or 2Ag as donor state. We propose that the commonly postulated partial intramolecular charge transfer (ICT) character of a donating Per state can be assigned to the relaxed 1Bu state, which takes on ICT character. By assuming that both 1Bu and 2Ag are able to donate to the Chl a Q band, one can explain why different chlorophyll species in PCP exhibit different acceptor capabilities.PostprintPeer reviewe
Measurement of $CP$ asymmetry in $D^0\rightarrow K^-K^+$ decays

A measurement of the time-integrated $CP$ asymmetry in the Cabibbo-suppressed
decay $D^0\rightarrow K^-K^+$ is performed using pp collision data,
corresponding to an integrated luminosity of 3fb$^{-1}$, collected with the
LHCb detector at centre-of-mass energies of 7 and 8 TeV. The flavour of the
charm meson at production is determined from the charge of the pion in
$D^{*+}\rightarrow D^0 \pi^+$ and $D^{*-}\rightarrow \bar{D^0} \pi^-$ decays.
The time-integrated $CP$ asymmetry $A_{CP}(K^-K^+)$ is obtained assuming
negligible $CP$ violation in charm mixing and in Cabibbo-favoured
$D^0\rightarrow K^-\pi^+$, $D^+\rightarrow K^-\pi^+\pi^+$ and $D^+\rightarrow
\bar{K^0}\pi^+$ decays used as calibration channels. It is found to be
$A_{CP}(K^-K^+)=(0.14\pm0.15(stat)\pm0.10(syst))\%$. A combination of this
result with previous LHCb measurements yields
$A_{CP}(K^-K^+)=(0.04\pm0.12(stat)\pm0.10(syst))\%$,
$A_{CP}(\pi^-\pi^+)=(0.07\pm0.14(stat)\pm0.11(syst))\%$. These are the most
precise measurements from a single experiment. The result for $A_{CP}(K^-K^+)$
is the most precise determination of a time-integrated $CP$ asymmetry in the
charm sector to date, and neither measurement shows evidence of CP asymmetry.Comment: All figures and tables, along with any supplementary material and
  additional information, are available at
  https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-035.htm
A Field Study on the Elicitation and Classification of Defects for
  Defect Models

Defect models capture faults and methods to provoke failures. To integrate
such defect models into existing quality assurance processes, we developed a
defect model lifecycle framework, in which the elicitation and classification
of context-specific defects forms a crucial step. Although we could gather
first insights from its practical application, we still have little knowledge
about its benefits and limitations. We aim at qualitatively analyzing the
context-specific elicitation and classification of defects to explore the
suitability of our approach for practical application. We apply case study
research in multiple contexts and analyze (1) what kind of defects we can
elicit and the degree to which the defects matter to a context only, (2) the
extent to which it leads to results useful enough for describing and
operationalizing defect models, and (3) if there is a perceived additional
immediate benefit from a practitioner's perspective. Our results strengthen our
confidence on the suitability of our approach to elicit defects that are
context-specific as well as context-independent. We conclude so far that our
approach is suitable to provide a blueprint on how to elicit and classify
defects for specific contexts to be used for the improvement of quality
assurance techniques
Search for high-mass resonances decaying into τ-lepton pairs in pp collisions at √ s = 7TeV

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMA search for high-mass resonances decaying into τ +τ - is performed using a data sample of pp collisions at √s=7TeV. The data were collected with the CMS detector at the LHC and correspond to an integrated luminosity of 4.9 fb -1. The number of observed events is in agreement with the standard model prediction. An upper limit on the product of the resonance cross section and branching fraction into τ-lepton pairs is calculated as a function of the resonance mass. Using the sequential standard model resonance ZSSM' and the superstring-inspired E 6 model with resonance Zψ' as benchmarks, resonances with standard model couplings with masses below 1.4 and 1.1 TeV, respectively, are excluded at 95% confidence levelWe congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC machine. We thank the technical and administrative staff at CERN and other CMS institutes, and acknowledge support from: FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); MSI (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MON, RosAtom, RAS and RFBR (Russia); MSTD (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA
Sublingual immunotherapy in children with allergic rhinoconjunctivitis mono-sensitized to house-dust-mites: a double-blind-placebo-controlled randomised trial.

Background Although sublingual immunotherapy (SLIT) has been demonstrated to be a safe and efficient treatment in children with seasonal allergic rhinitis (AR), there is little evidence on the efficacy of SLIT with house-dust-mite (HDM) extract in children with isolated perennial AR. Objectives We sought to assess the clinical efficacy and safety of HDM-SLIT in children with isolated allergic rhinitis-conjunctivitis mono-sensitized to HDM without asthma symptoms. Methods Twenty-two children (aged 5-10 years) with perennial AR and conjunctivitis symptoms mono-sensitized to Dermatophagoides pteronyssinus and Dermatophagoides farinae were enrolled. During a 2 months run-in period, symptom and medication scores, lung functions, bronchial hyperreactivity, nasal provocation and skin prick tests were evaluated. Subjects were randomized to active or placebo using a double-blind method. A total of eighteen subjects were randomised to receive either active SLIT or placebo for 12 months. Daily symptom and medication scores, baseline lung functions, bronchial hyperreactivity, nasal provocation and skin prick tests were recorded and re-evaluated at the end of treatment. Results After one year of treatment, no significant differences were detected in the between groups and within group comparisons based on total rhinitis symptom/medication scores (p > 0.05). Skin reactivity to Dermatophagoides pteronyssinus was significantly reduced in HDM-SLIT compared to placebo group (p = 0.018). A significant reduction in nasal sensitivity was observed in SLIT group after one year treatment when compared to baseline (p = 0.04). Total conjunctivitis symptoms were reduced significantly in both active and lacebo group at the end of treatment compared to baseline. The proportion of patients with non-specific bronchial hyperreactivity increased to almost 3-fold in placebo group compared to baseline. Conclusion HDM-SLIT was not superior to placebo in reducing isolated rhinoconjunctivitis symptoms within 12 months of treatment. However, HDM-SLIT has a modulating effect on allergen-specific nasal and skin reactivity in isolated perennial AR children. Clinical Trial Registration The trial was registered at Anzctr.org.au number, ACTRN12613000315718. © 2013 Elsevier Ltd. All rights reserved
A data comparison between a traditional and the single-step β-galactosidase assay.

This article describes reproducibility of a single-step automated β-galactosidase, and the equivalence of its data to the traditional assay ( Experiments in Molecular Genetics  [1]). This was done via a pairwise comparison of both methods using strains with Miller Unit [MU] values ranging from 0 to over 2000. The data presented in this article is associated with the research article entitled  A single-step method for mid to high throughput β-galactosidase assays in Escherichia coli using a microplate reader  [2]