pinecone/core-2020-05-10-deduplication huggingface dataset:
How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit

How do police respond to and manage complaints
of stalking? To answer this question, we conducted a
3-phase study. First, we reviewed the literature to identify
risk management tactics used to combat stalking. Second,
we asked a group of police officers to review those tactics
for completeness and group them into categories reflecting
more general risk management strategies. The result was 22
categories of strategies. Finally, we used qualitative
methods to evaluate the files of 32 cases referred to the
specialized anti-stalking unit of a metropolitan police
department. We coded specific risk management tactics
and strategies used by police. Results indicated that a
median number of 19 specific tactics from 7 general
strategies were used to manage risk. Also, the implementation
of strategies and tactics reflected specific characteristics of the
cases (e.g., perpetrator risk factors, victim vulnerability
factors), suggesting that the risk management decisions made
by police were indeed strategic in nature. Qualitative analyses
indicated that some of the strategies and tactics were more
effective than others. We discuss how these findings can be
used to understand and use stalking risk management more
generally, as well as improve research on the efficacy of risk
assessment and management for stalking
Cytomegalovirus serology and replication remain associated with solid organ graft rejection and graft loss in the era of prophylactic treatment

BACKGROUND  Cytomegalovirus (CMV) replication has been associated with more risk for solid organ graft rejection. We wondered whether this association still holds when patients at risk receive prophylactic treatment for CMV.  METHODS  We correlated CMV infection, biopsy-proven graft rejection, and graft loss in 1,414 patients receiving heart (n=97), kidney (n=917), liver (n=237), or lung (n=163) allografts reported to the Swiss Transplant Cohort Study.  RESULTS  Recipients of all organs were at an increased risk for biopsy-proven graft rejection within 4 weeks after detection of CMV replication (hazard ratio [HR] after heart transplantation, 2.60; 95% confidence interval [CI], 1.34-4.94, P<0.001; HR after kidney transplantation, 1.58; 95% CI, 1.16-2.16, P=0.02; HR after liver transplantation, 2.21; 95% CI, 1.53-3.17, P<0.001; HR after lung transplantation, 5.83; 95% CI, 3.12-10.9, P<0.001. Relative hazards were comparable in patients with asymptomatic or symptomatic CMV infection. The CMV donor or recipient serological constellation also predicted the incidence of graft rejection after liver and lung transplantation, with significantly higher rates of rejection in transplants in which donor or recipient were CMV seropositive (non-D-/R-), compared with D- transplant or R- transplant (HR, 3.05; P=0.002 for liver and HR, 2.42; P=0.01 for lung transplants). Finally, graft loss occurred more frequently in non-D- or non-R- compared with D- transplant or R- transplant in all organs analyzed. Valganciclovir prophylactic treatment seemed to delay, but not prevent, graft loss in non-D- or non-R- transplants.  CONCLUSION  Cytomegalovirus replication and donor or recipient seroconstellation remains associated with graft rejection and graft loss in the era of prophylactic CMV treatment
Precision Spectroscopy at Heavy Ion Ring Accelerator SIS300

Unique spectroscopic possibilities open up if a laser beam interacts with relativistic lithium-like ions stored in the heavy ion ring accelerator SIS300 at the future Facility for Antiproton and Ion Research FAIR in Darmstadt, Germany. At a relativistic factor gamma = 36 the 2P 1/2 level can be excited from the 2S 1/2 ground state for any element with frequency doubled dye-lasers in collinear geometry. Precise transition energy measurements can be performed if the fluorescence photons, boosted in forward direction into the X-ray region, are energetically analyzed with a single crystal monochromator. The hyperfine structure can be investigated at the 2P 1/2 - 2S 1/2 transition for all elements and at the 2P 3/2 - 2S 1/2 transition for elements with Z < 50. Isotope shifts and nuclear moments can be measured with unprecedented precision, in principle even for only a few stored radioactive species with known nuclear spin. A superior relative line width in the order of 5E-7 may be feasible after laser cooling, and even polarized external beams may be prepared by optical pumping
A short survey on protein blocks.

International audienceProtein structures are classically described in terms of secondary structures. Even if the regular secondary structures have relevant physical meaning, their recognition from atomic coordinates has some important limitations such as uncertainties in the assignment of boundaries of helical and β-strand regions. Further, on an average about 50% of all residues are assigned to an irregular state, i.e., the coil. Thus different research teams have focused on abstracting conformation of protein backbone in the localized short stretches. Using different geometric measures, local stretches in protein structures are clustered in a chosen number of states. A prototype representative of the local structures in each cluster is generally defined. These libraries of local structures prototypes are named as "structural alphabets". We have developed a structural alphabet, named Protein Blocks, not only to approximate the protein structure, but also to predict them from sequence. Since its development, we and other teams have explored numerous new research fields using this structural alphabet. We review here some of the most interesting applications
Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant.

International audienceThe release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades. PAHs are hydrophobic molecules which can accumulate in high concentrations in sediments acting then as major secondary sources. Fish contamination can occur through contact or residence nearby sediments or though dietary exposure. In this study, we analyzed certain physiological traits in unexposed fish (F1) issued from parents (F0) exposed through diet to three PAH mixtures at similar and environmentally relevant concentrations but differing in their compositions. For each mixture, no morphological differences were observed between concentrations. An increase in locomotor activity was observed in larvae issued from fish exposed to the highest concentration of a pyrolytic (PY) mixture. On the contrary, a decrease in locomotor activity was observed in larvae issued from heavy oil mixture (HO). In the case of the third mixture, light oil (LO), a reduction of the diurnal activity was observed during the setup of larval activity. Behavioral disruptions persisted in F1-PY juveniles and in their offspring (F2). Endocrine disruption was analyzed using cyp19a1b:GFP transgenic line and revealed disruptions in PY and LO offspring. Since no PAH metabolites were dosed in larvae, these findings suggest possible underlying mechanisms such as altered parental signaling molecule and/or hormone transferred in the gametes, eventually leading to early imprinting. Taken together, these results indicate that physiological disruptions are observed in offspring of fish exposed to PAH mixtures through diet
Vote-Independence: A Powerful Privacy Notion for Voting Protocols

International audienceRecently an attack on ballot privacy in Helios has been discovered [20], which is essentially based on copying other voter's votes. To capture this and similar attacks, we extend the classical threat model and introduce a new security notion for voting protocols: Vote-Independence. We give a formal definition and analyze its relationship to established privacy properties such as Vote-Privacy, Receipt-Freeness and Coercion-Resistance. In particular we show that even Coercion-Resistant protocols do not necessarily ensure Vote-Independence
Simulated solvation of organic ions II: Study of linear alkylated

International audienceWe investigated the solvation of carboxylate ions from formate to hexanoate, in droplets of 50 to 1000 water molecules and neat water, by computations using standard molecular dynamics and sophisticated polarizable models. The carboxylate ions from methanoate to hexanoate show strong propensity for the air/water interface in small droplets. Only the ions larger than propanoate retain propensity for the interface in larger droplets, where their enthalpic stabilization by ion/water dispersion is reduced there by 3 kcal mol–1 per CH2 group. This is compensated by entropy effects over +3.3 cal mol–1 K–1 per CH2 group. On the surface, the anionic headgroups are strongly oriented toward the aqueous core, while the hydrophobic alkyl chains are repelled into air and lose their structure-making effects. These results reproduce the structure-making effects of alkyl groups in solution, and suggest that the hydrocarbon chains of ionic headgroups and alkyl substituents solvate independently. Extrapolation to bulk solution using standard extrapolation schemes yields absolute carboxylate solvation energies. The results for formate and acetate yield a proton solvation enthalpy of about 270 kcal mol–1, close to the experiment-based value. The largest carboxylate ions yield a value smaller by about 10 kcal mol–1, which requires studies in much larger droplets
Age, geochemical characteristics and petrogenesis of Cenozoic intraplate alkaline volcanic rocks in the Bafang region, West Cameroon

International audienceThe origin of the volcanism in the Cameroon Volcanic Line and the nature of its mantle sources are still highly controversial. We present major and trace element compositions as well as Sr–Nd–Pb–Hf isotopic results on mafic and intermediate lavas from the Bafang area in the central part of the Cameroon Volcanic Line. The lavas range from basanites and basalts to hawaiites and mugearites with an alkaline affinity and were emplaced between 10 and 6 Ma ago. The evolution from basalts and basanites to more differentiated rocks involved fractionation of olivine, clinopyroxene and Fe–Ti oxides, but the isotopic compositions show that crustal contamination processes affected some magmas during their ascent in the crust. Basalts and basanites originated from a garnet-bearing mantle source and their differences are mostly due to variable degrees of partial melting. The isotopic composition of the uncontaminated samples imply the participation of three distinct mantle components, the depleted MORB mantle (not dominant), an enriched component and a Pb radiogenic component similar to the source of the Mount Cameroon. Combined with previously published isotopic data from the Cameroon Volcanic Line, our new results indicate that the source of the volcanism mostly reside in the lithospheric mantle and is different from what can be expected from the melting of a mantle accreted from or modified during the emplacement of the St. Helena mantle plume
Water quality assessment by means of HFNI valvometry and high-frequency data modeling

International audienceThe high-frequency measurements of valve activity in bivalves (e.g., valvometry) over a long period of time and in various environmental conditions allow a very accurate study of their behaviors as well as a global analysis of possible perturbations due to the environment. Valvom- etry uses the bivalve's ability to close its shell when exposed to a contaminant or other abnormal environmental conditions as an alarm to indicate possible perturbations in the environment. The modeling of such high-frequency serial valvom- etry data is statistically challenging, and here, a nonparametric approach based on kernel estima- tion is proposed. This method has the advantage of summarizing complex data into a simple den- sity profile obtained from each animal at every 24-h period to ultimately make inference about time effect and external conditions on this profile. The statistical properties of the estimator are pre- sented. Through an application to a sample of 16 oysters living in the Bay of Arcachon (France), we demonstrate that this method can be used to first estimate the normal biological rhythms of permanently immersed oysters and second to de- tect perturbations of these rhythms due to changes in their environment. We anticipate that this ap- proach could have an important contribution to the survey of aquatic systems
Local and global hydrological contributions to gravity variations observed in Strasbourg

International audienceWe investigate the contribution of local and global hydrology to the superconducting gravimeter (SG) installed in the Strasbourg observatory.Adeterministic approach is presented to account for the contribution of water storage variations in the soils in the vicinity of the gravimeter: both amount and distribution of water masses are determined before calculating Newtonian attraction. No adjustment is performed on gravity time series. Two multi-depth Frequency Domain Reflectometer (FDR) probes have been installed to monitor the amount of water stored in the soil layer above the gravimeter. Since August 2005, they have been monitoring the variation of the water content of the entire soil thickness. Several investigations have been undertaken in order to estimate the distribution of water masses: a precise local DEM (Digital Elevation Model) has been determined using differential GPS. The geometry and heterogeneity of the soil layer have been evaluated thanks to geophysical and geomechanical prospections. The comparison between observed and modelled gravity variations shows that daily up to seasonal variations are in good agreement. For long-term variations, deep water storage and other processes have to be modelled to explain recorded gravity variations
Geostatistical approach for the assessment of the water reservoir capacity in arid regions: a case study of the Akdarya reservoir, Uzbekistan

International audienceThe paper presents the results of a new geostatistical approach to generate bathymetric surface models from point measurement converted into continuous contour surfaces of reservoir bottoms in Uzbekistan. Sedimentation of reservoirs raises engineering, environmental and economical issues for the communities around the world in areas affected by a strong water deficit. Because of Uzbekistan's arid climatic conditions, and uneven spatial and temporal water resources distribution, responsive and innovative water availability assessment surveys of all major water reservoirs are required. Bathymetric surveying is a traditional method that is carried out for the estimation of reservoir volumes and surface areas of the corresponding reservoir stages in order to assess the water availability. Volume and surface area differences derived from multiple surveys of a reservoir provide storage loss estimates over time due to sedimentation. However, two main factors, such as intensive field data measurement and post data-processing, often limit the frequency of these surveys. Alternatively, innovative depth measurement technologies coupled with contouring and surface mapping programs provide automated reservoir volume and surface area calculations. This significantly reduces time, workload and financial burdens for reservoir sedimentation projects. This research proposes the use of geostatistical approach to assess the reservoir sedimentation in the Akdarya reservoir of Uzbekistan. The geostatistical approach includes (semi-) variogram analysis and interpolation (kriging and simulations--turning bands) techniques predicting values at unsampled locations for generating digital bathymetric surface models of reservoir bottom conditions in order to calculate the volume and surface area at a given water elevation. The simulation enables to have range of reservoir volumes and surface areas with the same probability, in comparison to the kriging and traditional methods. This gives a real estimation of the resource availability for water operators to manage natural resources and hydraulic infrastructure in a sustainable manner
CHERCAM: A Cherenkov imager for the CREAM experiment

International audienceThe CREAM experiment (Cosmic Ray Energetics and Mass) is dedicated to the measurement of the energy spectrum of nuclear elements in cosmic rays, over the range 10$^{12}$ to 10$^{15}$ eV. The individual elements separation, which is a key feature of CREAM, requires instruments with strong identification capabilities. A proximity focused type of Cherenkov imager, CHERCAM (CHERenkov CAMera), providing both a good signature of downgoing Z=1 particles and good single element separation through the whole range of nuclear charges [Buénerd et al. 28th ICRC, Tsukuba, OG 1.5, 2003, p. 2157], is under development. After a brief introduction, the main features and the construction status of the CHERCAM are being summarized
Semianalytical solution for the stress distribution in notched tubes

International audienceThe aim of this paper is to present an alternative solution to the finite element method for the determination of the elastic stress field for an axi-symmetric notched tube under tension and bending loadings. The proposed solution is an extension of the work of Filippi and Lazzarin (2004) [8] to tubular specimens. It provides the stress field distribution along the notch bisector. A good agreement was found between the solution proposed in the present paper and the results from a finite element analysis. A sensitivity analysis is performed to establish the domain of validity of the solution with respect to the dimensions of the notched tube
A study of depth/texture bit-rate allocation in multi-view video plus depth compression

International audienceMulti-view video plus depth (MVD) data offer a reliable representation of three-dimensional (3D) scenes for 3D video applications. This is a huge amount of data whose compression is an important challenge for researchers at the current time. Consisting of texture and depth video sequences, the question of the relationship between these two types of data regarding bit-rate allocation often raises. This paper questions the required ratio between texture and depth when encoding MVD data. In particular, the paper investigates the elements impacting on the best bit-rate ratio between depth and color: total bit-rate budget, input data features, encoding strategy, and assessed view
Polynomial Algorithms for Subisomorphism of nD Open Combinatorial Maps

International audienceCombinatorial maps describe the subdivision of objects in cells, and incidence and adjacency relations between cells, and they are widely used to model 2D and 3D images. However, there is no algorithm for comparing combinatorial maps, which is an important issue for image processing and analysis. In this paper, we address two basic comparison problems, i.e., map isomorphism, which involves deciding if two maps are equivalent, and submap isomorphism, which involves deciding if a copy of a pattern map may be found in a target map. We formally define these two problems for nD open combinatorial maps, we give polynomial time algorithms for solving them, and we illustrate their interest and feasibility for searching patterns in 2D and 3D images, as any child would aim to do when he searches Wally in Martin Handford's books
Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting.

International audienceSystemic gene delivery systems are needed for therapeutic application to organs that are inaccessible by percutaneous injection. Currently, the main objective is the development of a stable and non-toxic vector that can encapsulate and deliver foreign genetic material to target cells. To this end, DNA, complexed with cationic lipids i.e. DOTAP/DOPE, was encapsulated into lipid nanocapsules (LNCs) leading to the formation of stable nanocarriers (DNA LNCs) with a size inferior to 130 nm. Amphiphilic and flexible poly (ethylene glycol) (PEG) polymer coatings [PEG lipid derivative (DSPE-mPEG(2000)) or F108 poloxamer] at different concentrations were selected to make DNA LNCs stealthy. Some of these coated lipid nanocapsules were able to inhibit complement activation and were not phagocytized in vitro by macrophagic THP-1 cells whereas uncoated DNA LNCs accumulated in the vacuolar compartment of THP-1 cells. These results correlated with a significant increase of in vivo circulation time in mice especially for DSPE-mPEG(2000) 10 mm and an early half-life time (t(1/2) of distribution) 5-fold greater than for non-coated DNA LNCs (7.1 h vs 1.4 h). Finally, a tumor accumulation assessed by in vivo fluorescence imaging system was evidenced for these coated LNCs as a passive targeting without causing any hepatic damage
Improvement in the determination by 1/f noise measurements of the interface state distribution in polysilicon TFTs in relation with the compensation law of Meyer Neldel

International audienceLow-frequency (1/f ) noise is studied in N-channel furnace solid phase crystallized (FSPC) and in laser solid phase crystallized (LSPC) polysilicon TFTs biased from weak to strong inversion. Noise analysis is supported by the theory of charge carrier trapping/detrapping at the interface tunnelling into gate oxide traps. The distribution of interface trap states (NT) is deduced from the number of carriers trapped into the oxide. Noise measurements for devices biased from weak to moderate inversion allow the determination of the distribution of deep level trap states associated with dangling bonds type defects (NTdb); whereas measurements from moderate to strong inversion give the distribution of shallow level trap states (NTts) associated with strained bonds defects. The noise analysis clearly shows that the slope of both exponential distributions equals to the reverse of the Meyer Neldel energy EMN (0.035 eV and 0.055eV for FSPC and LSPC TFT respectively). For LSPC devices the resulting distribution of interface states (NT=NTdb+NTts) is one decade lower and it is attributed to the effects of the laser annealing on the active layer crystal quality
Effect of peroxides on spermine transport in rat brain and liver mitochondria.

The polyamine spermine is transported into the matrix of various types of mitochondria by a specific uniporter system identified as a protein channel. This mechanism is regulated by the membrane potential; other regulatory effectors are unknown. This study analyzes the transport of spermine in the presence of peroxides in both isolated rat liver and brain mitochondria, in order to evaluate the involvement of the redox state in this mechanism, and to compare its effect in both types of mitochondria. In liver mitochondria peroxides are able to inhibit spermine transport. This effect is indicative of redox regulation by the transporter, probably due to the presence of critical thiol groups along the transport pathway, or in close association with it, with different accessibility for the peroxides and performing different functions. In brain mitochondria, peroxides have several effects, supporting the hypothesis of a different regulation of spermine transport. The fact that peroxovanadate can inhibit tyrosine phosphatases in brain mitochondria suggests that mitochondrial spermine transport is regulated by tyrosine phosphorylation in this organ. In this regard, the evaluation of spermine transport in the presence of Src inhibitors suggests the involvement of Src family kinases in this process. It is possible that phosphorylation sites for Src kinases are present in the channel pathway and have an inhibitory effect on spermine transport under regulation by Src kinases. The results of this study suggest that the activity of the spermine transporter probably depends on the redox and/or tyrosine phosphorylation state of mitochondria, and that its regulation may be different in distinct organs