pinecone/core-2020-05-10-deduplication huggingface dataset:
Tracking Advanced Planetary Systems (TAPAS) with HARPS-N: III. HD 5583 and BD+15 2375 - Two cool giants with warm companions

Context. Evolved stars are crucial pieces for our understanding of the dependency of the planet formation mechanism on the stellar mass and for exploring the mechanism involved in star-planet interactions more deeply. Over the last ten years, we have monitored about 1000 evolved stars for radial velocity variations in the search for low-mass companions under the Penn State - Torun Centre for Astronomy Planet Search program with the Hobby-Eberly Telescope (HET). Selected prospective candidates that required higher RV precision measurements were followed with HARPS-N at the 3.6 m Telescopio Nazionale Galileo under the TAPAS project. Aims. We aim to detect planetary systems around evolved stars to be able to build sound statistics on the frequency and intrinsic nature of these systems, and to deliver in-depth studies of selected planetary systems with evidence of star-planet interaction processes. Methods. For HD 5583 we obtained 14 epochs of precise RV measurements that were collected over 2313 days with the HET, and 22 epochs of ultra-precise HARPS-N data collected over 976 days. For BD+15 2375 we collected 24 epochs of HET data over 3286 days and 25 epochs of HARPS-S data over 902 days. Results. We report the discovery of two planetary mass objects that are orbiting two evolved red giant stars: HD 5583 has a msini = 5.78MJ companion at 0.529 AU in a nearly circular orbit (e = 0.076), the closest companion to a giant star detected with the RV technique, and BD+15 2735 that, with a msini = 1.06MJ, holds the record for the lightest planet orbiting an evolved star found so far (in a circular e = 0.001, 0.576 AU orbit). These are the third and fourth planets found within the TAPAS project, a HARPS-N monitoring of evolved planetary systems identified with the HETA.N., MoA, G.N., B.D., and MiA were supported by the Polish National Science Centre Grant UMO-2012/07/B/ST9/04415. MoA also acknowledges the Mobility+III fellowship from the Polish Ministry of Science and Higher Education. K.K. was funded in part by the Gordon and Betty Moore Foundation’s Data-Driven Discovery Initiative through Grant GBMF4561.E.V. work was supported by the Spanish Ministerio de Ciencia e Innovacion (MICINN), Plan Nacional de Astronomia y Astrofisica, under Grant AYA2013-45347P. A.W. was supported by the NASA Grant NNX09AB36G.The Center for Exoplanets and Habitable Worlds is supported by the Pennsylvania State University, the Eberly College of Science, and the Pennsylvania Space Grant Consortiu
Self-referential memory in autism spectrum disorder and typical development: Exploring the ownership effect

Owned objects occupy a privileged cognitive processing status and are viewed almost as extensions of the self. It has been demonstrated that items over which a sense of ownership is felt will be better recalled than other items. As autism spectrum disorder (ASD) is characterised by an impaired self-concept, people with ASD may not demonstrate this ownership effect. Two experiments were conducted which replicate Cunningham, Turk, Macdonald, & Macrae (2008). In Experiment 1, neurotypical adults completed a card sorting task and cards belonging to the ‘self’ were better remembered than cards belonging to the ‘other’. In the second experiment, adults with ASD recalled self- and other-referent items equally well. These results shed light both on the nature of the self-concept in ASD and the relationship between sense of self and the ownership effect
A WIDELY SEPARATED, HIGHLY OCCLUDED COMPANION TO THE NEARBY LOW-MASS T TAURI STAR TWA 30

We report the discovery of TWA 30B, a wide (~3400 AU), co-moving M dwarf companion to the nearby (~42 pc) young star TWA 30. Companionship is confirmed from their statistically consistent proper motions and radial velocities (RVs), as well as a chance alignment probability of only 0.08%. Like TWA 30A, the spectrum of TWA 30B shows signatures of an actively accreting disk (H I and alkali line emission) and forbidden emission lines tracing outflowing material ([O I], [O II], [O III], [S II], and [N II]). We have also detected [C I] emission in the optical data, marking the first such detection of this line in a pre-main-sequence star. Negligible RV shifts in the emission lines relative to the stellar frame of rest (ΔV lsim 30 km s–1) indicate that the outflows are viewed in the plane of the sky and that the corresponding circumstellar disk is viewed edge-on. Indeed, TWA 30B appears to be heavily obscured by its disk, given that it is 5 mag fainter than TWA 30A at K band despite having a slightly earlier spectral type (M4 versus M5). The near-infrared spectrum of TWA 30B also evinces an excess that varies on day timescales, with colors that follow classical T Tauri tracks as opposed to variable reddening (as is the case for TWA 30A). Multi-epoch data show this excess to be well modeled by a black body component with temperatures ranging from 630 to 880 K and emitting areas that scale inversely with the temperature. The variable excess may arise from disk structure such as a rim or a warp at the inner disk edge located at a radial distance of ~3-5 R ☉. As the second and third closest actively accreting and outflowing stars to the Sun (after TWA 3), TWA 30AB presents an ideal system for a detailed study of star and planetary formation processes at the low-mass end of the hydrogen-burning spectrum.George HerbigToby OwenNational Science Foundation (U.S.)United States. National Aeronautics and Space Administratio
Measurement of the low-mass Drell-Yan differential cross section at √s = 7 TeV using the ATLAS detector

The differential cross section for the process Z/γ [superscript ∗] → ℓℓ (ℓ = e, μ) as a function of dilepton invariant mass is measured in pp collisions at √s = 7 TeV at the LHC using the ATLAS detector. The measurement is performed in the e and μ channels for invariant masses between 26 GeV and 66 GeV using an integrated luminosity of 1.6 fb[superscript −1] collected in 2011 and these measurements are combined. The analysis is extended to invariant masses as low as 12 GeV in the muon channel using 35 pb[superscript −1] of data collected in 2010. The cross sections are determined within fiducial acceptance regions and corrections to extrapolate the measurements to the full kinematic range are provided. Next-to-next-to-leading-order QCD predictions provide a significantly better description of the results than next-to-leading-order QCD calculations, unless the latter are matched to a parton shower calculation.United States. Dept. of EnergyNational Science Foundation (U.S.)Brookhaven National Laborator
A note on the equilibria of an economic model with local competition ‘‘à la Cournot’’

Agraïments: This work was supported in part by Fundación Séneca de la Región de Murcia, grant number 08667/PI/08 and JCCM (Junta de Comunidades de Castilla-La Mancha), grant number PEII09-0220-0222.Guirao and Rubio (2010) [12] introduce an economic model, which generalizes the classical duopoly of Cournot type, where the competitors are located around a circle or a line and each firm competes ‘‘à la Cournot’’ with its right and left neighboring. For the case of having three and four players, we describe completely the bifurcations of equilibria in terms of the production costs of each firm and we study the stability of them. Moreover, for the case of four players we provide some information on the two-periodic orbits of the system
Blood, Thunder and Showgirls: The Merchant Navy on the BBC, 1939–1945

This article examines the representation of the Merchant Navy on BBC radio in Britain during the Second World War. It discusses how this essential, but dangerous, wartime role was presented to the British public by arguably the most prevalent wartime cultural medium. It uses extensive research in the BBC’s Written Archive Centre, using both radio broadcasts and listener research, to understand how the role of the Merchant Navy was portrayed and understood during the war. This article argues that, unlike other civilian occupations, men of the Merchant Navy were presented as brave and courageous under enemy fire and were consequently given access to much of the prestige generally reserved for the armed forces
Spectroscopic and photometric analysis of the early-type spectroscopic binary HD 161853 in the centre of an H ii region (Research Note)

Aims. We study the O-type star HD 161853, which has been noted as a probable double-lined spectroscopic binary system.
Methods. We secured high-resolution spectra of HD 161853 during the past nine years. We separated the two components in the system and measured their respective radial velocities for the first time.
Results. We confirm that HD 161853 is an ~1 Ma old binary system consisting of an O8 V star (MA,RV ≥ 22 M⊙) and a B1–3 V star (MB,RV ≥ 7.2 M⊙) at about 1.3 kpc. From the radial velocity curve, we measure an orbital period P = 2.66765 ± 0.00001 d and an eccentricity e = 0.121 ± 0.007. Its V-band light curve is constant within 0.014 mag and does not display eclipses, from which we impose a maximum orbital inclination i = 54 deg. HD 161853 is probably associated with an H ii region and a poorly investigated very young open cluster. In addition, we detect a compact emission region at 50 arcsec to HD 161853 in 22 μm-WISE and 24 μm-Spitzer images, which may be identified as a dust wave piled up by the radiation pressure of the massive binary system.Fil: Gamen, Roberto Claudio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Astrofísica de la Plata; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Putkuri, C.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Astrofísica de la Plata; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Morrell, Nidia Irene. Las Campanas Observatory. Carnegie Observatories; ChileFil: Barba, Rodolfo Hector. Universidad de la Serena; ChileFil: Arias, J. I.. Universidad de la Serena; ChileFil: Maíz Apellániz, J.. Centro de Astrobiología; EspañaFil: Walborn, N. R.. Space Telescope Science Institute; Estados UnidosFil: Sota, A.. Consejo Superior de Investigaciones Cientificas. Instituto de Astrofísica de Andalucía; EspañaFil: Alfaro, E. J.. Consejo Superior de Investigaciones Cientificas. Instituto de Astrofísica de Andalucía; Españ
Search for heavy resonances decaying to a Z boson and a photon in pp collisions at s=13 TeV with the ATLAS detector

AbstractThis Letter presents a search for new resonances with mass larger than 250 GeV, decaying to a Z boson and a photon. The dataset consists of an integrated luminosity of 3.2 fb−1 of pp collisions collected at s=13 TeV with the ATLAS detector at the Large Hadron Collider. The Z bosons are identified through their decays either to charged, light, lepton pairs (e+e−, μ+μ−) or to hadrons. The data are found to be consistent with the expected background in the whole mass range investigated and upper limits are set on the production cross section times decay branching ratio to Zγ of a narrow scalar boson with mass between 250 GeV and 2.75 TeV
Has a Higgs-flavon with a 750 GeV mass been detected at the LHC13?

AbstractHiggs-flavon fields appear as a part of the Froggatt–Nielsen (FN) mechanism, which attempts to explain the hierarchy of Yukawa couplings. We explore the possibility that the 750 GeV diphoton resonance recently reported at the LHC13 could be identified with a low-scale Higgs-flavon field HF and find the region of the parameter space consistent with CMS and ATLAS data. It is found that the extra vector-like fermions of the ultraviolet completion of the FN mechanism are necessary in order to reproduce the observed signal. We consider a standard model (SM) extension that contains two Higgs doublets (a standard one and an inert one) and one complex FN singlet. The inert doublet includes a stable neutral boson, which provides a viable dark matter candidate, while the mixing of the standard doublet and the FN singlet induces flavor violation in the Higgs sector at the tree-level. Constraints on the parameters of the model are derived from the LHC Higgs data, which include the search for the lepton flavor violating decay of the SM Higgs boson h→μ¯τ. It is also found that in some region of the parameter space the model may give rise to a large branching ratio for the HF→hh decay, of the order of 0.1, which could be searched for at the LHC
Automated microbeam observation environment for biological analysis—Custom portable environmental control applied to a vertical microbeam system

AbstractVertical Microbeams (VMB) are used to irradiate individual cells with low MeV energy ions. The irradiation of cells using VMBs requires cells to be removed from an incubator; this can cause physiological changes to cells because of the lower CO2 concentration, temperature and relative humidity outside of the incubator. Consequently, for experiments where cells require irradiation and observation for extended time periods, it is important to provide a controlled environment. The highly customised nature of the microscopes used on VMB systems means that there are no commercially available environmentally controlled microscope systems for VMB systems. The Automated Microbeam Observation Environment for Biological Analysis (AMOEBA) is a highly flexible modular environmental control system used to create incubator conditions on the end of a VMB. The AMOEBA takes advantage of the recent “maker” movement to create an open source control system that can be easily configured by the user to fit their control needs even beyond VMB applications. When applied to the task of controlling cell medium temperature, CO2 concentration and relative humidity on VMBs it creates a stable environment that allows cells to multiply on the end of a VMB over a period of 36h, providing a low-cost (costing less than $2700 to build), customisable alternative to commercial time-lapse microscopy systems. AMOEBA adds the potential of VMBs to explore the long-term effects of radiation on single cells opening up new research areas for VMBs
Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

AbstractAttempts to find a cure for HIV infection are hindered by the presence of viral reservoirs that resist highly active antiretroviral therapy. To identify the properties of these reservoirs, four SIV239-infected Rhesus macaques were treated with combined antiretroviral therapy (cART) for 1year. While plasma viral RNA (vRNA) was effectively suppressed, a systemic analysis revealed that vRNA was distributed in the following order: lymphatic tissues>lungs and intestine>other tissues. Histochemistry yielded no cells with viral signals. To increase the chance of detection, two additional SIV-infected animals were treated and analyzed on Day 10 after the cessation of cART. These animals exhibited similar vRNA distribution patterns to the former animals, and immunohistochemistry revealed Nef-positive T lymphocytes predominantly in the follicles of mesenteric lymph nodes (MLNs). These data suggest that lymphatic tissues, including MLNs, contain major cellular reservoirs that cause rebound of plasma viremia upon cessation of therapy
Bacterial mechanosensitive channels: progress towards an understanding of their roles in cell physiology

Bacterial mechanosensitive channels sense the changes in lateral tension in the bilayer of the cytoplasmic membrane generated by rapid water flow into the cell. Two major structural families are found widely distributed across bacteria and archaea: MscL and MscS. Our understanding of the mechanisms of gating has advanced rapidly through genetic analysis, structural biology and electrophysiology. It is only recently that the analysis of the physiological roles of the channels has kept pace with mechanistic studies. Recent advances have increased our understanding of the role of the channels in preventing structural perturbation during osmotic transitions and its relationship to water flow across the membrane. It is to these recent developments that this review is dedicated
Comparing the impact of an acute exercise bout on plasma amino acid composition, intraerythrocytic Ca2+ handling, and red cell function in athletes and untrained subjects

AbstractThe N-methyl d-aspartate receptors (NMDARs) mediating Ca2+ uptake upon stimulation with glutamate and glycine were recently discovered in red blood cells (RBC) of healthy humans. Activation of these receptors with agonists triggered transient Ca2+-dependent decrease in hemoglobin oxygen affinity in RBC suspension. The aim of this study was to assess the potential physiological relevance of this phenomenon. Two groups formed by either healthy untrained volunteers or endurance athletes were subjected to a stepwise incremental cycling test to exhaustion. Plasma glutamate levels, activity of the NMDARs, and hemoglobin O2 affinity were measured in blood samples obtained before and after the exercise in both groups. Increase in plasma glutamate levels following exercise was observed in both groups. Transient Ca2+ accumulation in response to the NMDAR stimulation with NMDA and glycine was followed by facilitated Ca2+ extrusion from the RBC and compensatory decrease in cytosolic Ca2+ levels. Short-term activation of the receptors triggered a transient decrease in O2 affinity of hemoglobin in both groups. These exercise-induced responses were more pronounced in athletes compared to the untrained subjects. Athletes were initially presented with lower basal intracellular Ca2+ levels and hemoglobin oxygen affinity compared to non-trained controls. High basal plasma glutamate levels were associated with induction of hemolysis and formation of echinocytes upon stimulation with the receptor agonists. These findings suggest that glutamate release occurring during exhaustive exercise bouts may acutely facilitate O2 liberation from hemoglobin and improve oxygen delivery to the exercising muscle
Neutrino–antineutrino mass splitting in the Standard Model and baryogenesis

AbstractOn the basis of a previously proposed mechanism of neutrino–antineutrino mass splitting in the Standard Model, which is Lorentz and SU(2)×U(1) invariant but non-local to evade the CPT theorem, we discuss the possible implications of neutrino–antineutrino mass splitting on neutrino physics and baryogenesis. It is shown that non-locality within a distance scale of the Planck length, that may not be fatal to unitarity in a generic effective theory, can generate the neutrino–antineutrino mass splitting of the order of the observed neutrino mass differences, which is tested in oscillation experiments, and a non-negligible baryon asymmetry depending on the estimate of sphaleron dynamics. The one-loop order induced electron–positron mass splitting in the Standard Model is shown to be finite and estimated at ∼10−20 eV, well below the experimental bound <10−2 eV. The induced CPT violation in the K-meson in the Standard Model is expected to be even smaller and well below the experimental bound |mK−mK¯|<0.44×10−18 GeV
Application of pulsed UV-irradiation and pre-coagulation to control ultrafiltration membrane fouling in the treatment of micro-polluted surface water

AbstractA major cause of ultrafiltration (UF) membrane fouling is the accumulation of microorganisms and their associated soluble products. To mitigate fouling the application of pulsed short-wavelength ultraviolet (UVC) light (around 254 nm) within the membrane tank together with pre-coagulation was investigated. In mini-pilot-scale tests carried out in parallel with conventional pre-treatment (CUF), the impact of pulsed UV (CUF-UV) at different UV irradiances and fluxes on the increase of trans-membrane pressure (TMP) was evaluated and explained in terms of the quantity and nature of membrane deposits in the membrane cake layer and pores.The results indicated that at a flux of 20 L m−2 h−1, the pulsed UV (1 min within 31 min cycle) at 3.17 × 10−2 W/cm2 prevented any measureable increase in TMP over a period of 32 days, while there was a fourfold increase in TMP for the conventional pre-treatment. For the CUF-UV system the concentration of bacteria and soluble microbial products was much less than the conventional CUF system, and the cake layer was thinner and contained less biopolymers (proteins and polysaccharides). In addition, the pores of the CUF-UV membrane appeared to have less organic deposits, and particularly fractions with a high molecular weight (>10 kDa).At a lower UV irradiance (1.08 × 10−2 W/cm2), or higher flux (40 L m−2 h−1) with the same UV irradiance, there was a measurable increase in TMP, indicating some fouling of the CUF-UV membrane, but the rate of TMP development was significantly lower (∼50%) than the conventional CUF membrane system. Overall, the results show the potential advantages of applying intermittent (pulsed) UVC irradiation with coagulation to control UF membrane fouling
Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy

AbstractThe Axl receptor tyrosine kinase (RTK) has been established as a strong candidate for targeted therapy of cancer. However, the benefits of targeted therapies are limited due to acquired resistance and activation of alternative RTKs. Therefore, we asked if cancer cells are able to overcome targeted Axl therapies. Here, we demonstrate that inhibition of Axl by short interfering RNA or the tyrosine kinase inhibitor (TKI) BMS777607 induces the expression of human epidermal growth factor receptor 3 (HER3) and the neuregulin 1(NRG1)–dependent phosphorylation of HER3 in MDA-MB231 and Ovcar8 cells. Moreover, analysis of 20 Axl-expressing cancer cell lines of different tissue origin indicates a low basal phosphorylation of RAC-α serine/threonine-protein kinase (AKT) as a general requirement for HER3 activation on Axl inhibition. Consequently, phosphorylation of AKT arises as an independent biomarker for Axl treatment. Additionally, we introduce phosphorylation of HER3 as an independent pharmacodynamic biomarker for monitoring of anti-Axl therapy response. Inhibition of cell viability by BMS777607 could be rescued by NRG1-dependent activation of HER3, suggesting an escape mechanism by tumor microenvironment. The Axl-TKI MPCD84111 simultaneously blocked Axl and HER2/3 signaling and thereby prohibited HER3 feedback activation. Furthermore, dual inhibition of Axl and HER2/3 using BMS777607 and lapatinib led to a significant inhibition of cell viability in Axl-expressing MDA-MB231 and Ovcar8 cells. Therefore, we conclude that, in patient cohorts with expression of Axl and low basal activity of AKT, a combined inhibition of Axl and HER2/3 kinase would be beneficial to overcome acquired resistance to Axl-targeted therapies
Temperature Redistribution Modelling During Intermittent Microwave Convective Heating

AbstractMicrowave power is used for heating and drying processes because of its faster and volumetric heating capability. Non-uniformtemperature distributionduring microwaveapplication is a major drawbackof these processes. Intermittent application of microwavepotentially reduces the impact of non-uniformity and improves energy efficiencyby redistributing the temperature.However, temperature re-distribution during intermittent microwave heating has not been investigated adequately. Consequently, in this study, a coupled electromagnetic with heat and mass transfer model was developed using the finite element methodembedded in COMSOL-Multyphysics software. Particularly, the temperature redistribution due to intermittent heating was investigated. A series of experiments were performed to validate the simulation. The test specimen was an apple and the temperature distribution was closely monitored by a TIC (Thermal Imaging Camera). The simulated temperature profilematched closely with thermal images obtained from experiments