pinecone/core-2020-05-10-deduplication huggingface dataset:
Measurement of W+W- production and search for the Higgs boson in pp collisions at √s=7 TeV

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMA measurement of W+W− production in pp collisions at √ s = 7 TeV and a search for the Higgs boson are reported. The W+W− candidates are selected in events with two leptons, either electrons or muons. The measurement is performed using LHC data recorded with the CMS detector, corresponding to an integrated luminosity of 36 pb−1. The pp → W+W− cross section is measured to be 41.1±15.3 (stat)± 5.8 (syst) ± 4.5 (lumi) pb, consistent with the standard model prediction. Limits on WWγ and WWZ anomalous triple gauge couplings are set. The search for the standard model Higgs boson in the W+W− decay mode does not reveal any evidence of excess above backgrounds. Limits are set on the production of the Higgs boson in the context of the standard model and in the presence of a sequential fourth family of fermions with high masses. In the latter context, a Higgs boson with mass between 144 and 207 GeV/c2 is ruled out at 95% confidence levelWe wish to congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC machine. We thank the technical and administrative staff at CERN and other CMS institutes, and acknowledge support from: FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia); Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLPFAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTD (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA). Individuals have received support from the Marie-Curie programme and the European Research Council (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Associazione per lo Sviluppo Scientifico e Tecnologico del Piemonte (Italy); the Belgian Federal Science Policy Office; the Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); and the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium
Reciprocal relations between workplace bullying, anxiety, and vigor: a two-wave longitudinal study

This is an accepted manuscript of an article published by Taylor & Francis Group in Anxiety, Stress, & Coping: An International Journal 2015-03-11 available online: http://www.tandfonline.com/doi/pdf/10.1080/10615806.2015.1016003Workplace bullying has been classified as an extreme
social stressor in work contexts and has been repeatedly linked to several negative
consequences. However, little research has examined reversed or reciprocal relations
of bullying and outcomes. Design: We conducted a two-wave longitudinal study with
a time lag of six months. Methods: The study sample consisted of 348 employees of
the Spanish workforce. The present study examined longitudinal relationships between
workplace bullying, psychological health, and well-being. On the basis of conservation
of resources theory, we hypothesized that we would find reciprocal relations among study variables over time. Results: Results of cross-lagged structural equation modeling analyses supported our hypotheses. Specifically, it was found that Time 1 (T1) workplace bullying was negatively related to Time 2 (T2) vigor and positively related to T2 anxiety. Additionally, T1 anxiety and vigor had an effect on T2 workplace bullying. Conclusions: Overall, these findings support the validity of the theoretical models postulating a reciprocal bullying–outcome relationship, rather than simple one-way causal pathways approachesThis work was supported by the Spanish Ministry of Science and Innovation [grant number PSI2009-13661
Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus

Crimean-Congo hemorrhagic fever (CCHF) is a severe acute human disease with potential lethal outcome caused by a virus, Crimean-Congo hemorrhagic fever virus (CCHFV). Not much is known regarding how CCHFV infects cells, replicates and why it cause vascular dysfunction. To better understand CCHFV- pathogenesis increased knowledge regarding these issues is needed.



Viruses have to enter a host cell in order to replicate its genome and here we show that CCHFV entry occur by clathrin-mediated endocytosis and is pH- dependent.



A new in situ detection technique was establihed to visualize individual CCHFV cRNA and vRNA transcripts. Potential colocalization with the viral nucleocapsid protein (NP) was also investigated. cRNA was found to be more concentrated to particular regions within the cytoplasm and co-localized with CCHFV NP. While vRNA was detected throughout the cytoplasma not colocalizating with CCHFV NP.



It is not known if the vascular leakage observed in CCHF is due to direct virus infection or is immune-mediated. A new in vitro model system was therefore established and it was found that CCHFV has a preference for basolateral entry. However and surprisingly, using CCHFV-infected monocyte-derived dendritic cells (moDCs) or their supernatant, a preference for apical entry was observed. This indicate that the change in entry site could be due to soluble factors from the moDCs. Neither direct infection nor addition of CCHFV-infected moDCs affected the cellular permeability of the human polarized epithelial cell layer, indicating that other factors are most likely are causing the vascular leakage.



Taken together, we established several new in vitro model systems to study CCHFV’s interaction with host cells. We also demonstrated the entry pathway for CCHFV into cells. These data and tools will hopefully facilitate and promote research on virus-host interactions which in turn may result in the development of new antivirals and/or vaccines against CCHFV
Use of the QuantiFERON-TB Gold test in Japanese patients with sarcoidosis.

Background and objective
Mycobacterium tuberculosis has been proposed as a candidate agent for the cause of sarcoidosis. The QuantiFERON-TB Gold test has a higher specificity for detecting Mycobacterium tuberculosis infection than the conventional tuberculin skin test. This study aimed to investigate the rate of positive QuantiFERON-TB Gold results in Japanese sarcoidosis patients.
Patients and methods
The QuantiFERON-TB Gold test, an enzyme-linked immunosorbent assay, was used to assess the levels of interferon-gamma resulting from immune responses to Mycobacterium tuberculosis-specific antigens, namely early secretory antigen target 6 and culture filtrate protein 10, in 90 Japanese sarcoidosis patients.
Results
The QuantiFERON-TB Gold result was positive in 3 of the 90 patients tested.
Conclusion
The positivity rate of QuantiFERON-TB Gold was 3.3% in Japanese sarcoidosis patients
Nonlocalities and Fermi motion corrections in K- atoms

We evaluate the p-wave K-N amplitudes from the chiral Lagrangians and from there construct the p-wave part of the K- nucleus optical potential plus a small s-wave part induced from the elementary p-wave amplitude and the nuclear Fermi motion. Simultaneously, the momentum and energy dependence of the s-wave optical potential, previously developed, are taken into account and shown to generate a small p-wave correction to the optical potential. All the corrections considered are small compared to the leading s-wave potential, and lead to changes in the shifts and widths which are smaller than the experimental errors. A thorough study of the threshold region and low densities is conducted, revealing mathematical problems for which a physical solution is given
Portability improvement of LABCOM data acquisition system for the next-generation fusion experiments

The LABCOM data acquisition system (DAQ) has set a new world record of acquired data amount of 90 GB/shot in 2005?2006 campaign. Its CompactPCI-based new DAQ enables about 80 MB/s real-time acquisition for each plasma measurement. The basic performance of a DAQ unit has already good prospects for the next-generation fusion experiments, however, some surrounding utilities are not necessarily developed to construct 10 times larger DAQ system yet. The increasing number of parallel DAQ units has made the operational and maintenance burden very heavy. So, “more distributed acquisition and centralised operations” would become expected. Here, DAQ front-end consisting of some digitizer chassis, a timing module, and an acquisition computer has been entirely re-designed to realize a lower-cost and maintenance-free “DAQ box” for fusion plasma measurements. OS and softwares have been also remodelled to use free drivers on Linux. Network-bootable diskless computers are also desirable for reducing the possibility of hardware troubles, and it simultaneously realizes to omit first-tier data storage and reduce the migration operational cost. As a result, total hardware cost could be reduced almost one-fifth than the previous. This could be the way to realize 10 times larger fusion experiment in the near future
Slowly decaying resonances of charged massive scalar fields in the
  Reissner-Nordstr\"om black-hole spacetime

We determine the characteristic timescales associated with the linearized
relaxation dynamics of the composed
Reissner-Nordstr\"om-black-hole-charged-massive-scalar-field system. To that
end, the quasinormal resonant frequencies
$\{\omega_n(\mu,q,M,Q)\}_{n=0}^{n=\infty}$ which characterize the dynamics of a
charged scalar field of mass $\mu$ and charge coupling constant $q$ in the
charged Reissner-Nordstr\"om black-hole spacetime of mass $M$ and electric
charge $Q$ are determined {\it analytically} in the eikonal regime $1\ll
M\mu<qQ$. Interestingly, we find that, for a given value of the dimensionless
black-hole electric charge $Q/M$, the imaginary part of the resonant
oscillation frequency is a monotonically {\it decreasing} function of the
dimensionless ratio $\mu/q$. In particular, it is shown that the quasinormal
resonance spectrum is characterized by the asymptotic behavior $\Im\omega\to0$
in the limiting case $M\mu\to qQ$. This intriguing finding implies that the
composed Reissner-Nordstr\"om-black-hole-charged-massive-scalar-field system is
characterized by extremely long relaxation times $\tau_{\text{relax}}\equiv
1/\Im\omega\to\infty$ in the $M\mu/qQ\to 1^-$ limit.Comment: 8 page
Potential negative consequences of geoengineering on crop production: a study of Indian groundnut

Geoengineering has been proposed to stabilise global temperature, but its impacts on crop production and stability are not fully understood. A few case studies suggest that certain crops are likely to benefit from solar dimming geoengineering, yet we show geoengineering is projected to have detrimental effects for groundnut. Using an ensemble of crop-climate model simulations, we illustrate that groundnut yields in India undergo a statistically significant decrease of up to 20 % as a result of solar dimming geoengineering relative to RCP4.5. It is somewhat reassuring, however, to find that after a sustained period of 50 years of geoengineering crop yields return to the non-geoengineered values within a few years once the intervention is ceased
Temperature-controlled metal/ligand stoichiometric ratio in Ag-TCNE coordination networks

The deposition of tetracyanoethylene (TCNE) on Ag(111), both at Room Temperature (RT, 300 K) and low temperatures (150 K), leads to the formation of coordination networks involving silver adatoms, as revealed by Variable-Temperature Scanning Tunneling Microscopy. Our results indicate that TCNE molecules etch away material from the step edges and possibly also from the terraces, which facilitates the formation of the observed coordination networks. Moreover, such process is temperature dependent, which allows for different stoichiometric ratios between Ag and TCNE just by adjusting the deposition temperature. X-ray Photoelectron Spectroscopy and Density Functional Theory calculations reveal that charge-transfer from the surface to the molecule and the concomitant geometrical distortions at both sides of the organic/inorganic interface might facilitate the extraction of silver atoms from the step-edges and, thus, its incorporation into the observed TCNE coordination networksThis work has been financed by the Spanish MICINN (Project Nos. FIS2010-18847, FIS2012-33011, CTQ2010- 17006, CTQ2011-24652, Project CONSOLIDER-INGENIO EN NANOCIENCIA MOLECULAR Ref. No. CSD2007- 00010), and the Comunidad de Madrid (Project Nos. S2009/MAT1726 and FotoCarbon-S2013/MIT-2841
Measurement of the top quark mass in the tt¯→dilepton channel from s=8 TeV ATLAS data

The top quark mass is measured in the View the MathML sourcett¯→dilepton channel (lepton=e,μlepton=e,μ) using ATLAS data recorded in the year 2012 at the LHC. The data were taken at a proton–proton centre-of-mass energy of View the MathML sources=8 TeV and correspond to an integrated luminosity of about 20.2 fb−120.2 fb−1. Exploiting the template method, and using the distribution of invariant masses of lepton–b-jetb-jet pairs, the top quark mass is measured to be View the MathML sourcemtop=172.99±0.41 (stat)±0.74 (syst) GeV, with a total uncertainty of 0.84 GeV0.84 GeV. Finally, a combination with previous ATLAS mtopmtop measurements from View the MathML sources=7 TeV data in the View the MathML sourcett¯→dilepton and View the MathML sourcett¯→lepton+jets channels results in mtop=172.84±0.34 (stat)±0.61 (syst) GeVmtop=172.84±0.34 (stat)±0.61 (syst) GeV, with a total uncertainty of 0.70 GeV0.70 GeV.We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, HGF, and MPG, Germany; GSRT, Greece; RGC, Hong Kong SAR, China; ISF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW and NCN, Poland; FCT, Portugal; MNE/IFA, Romania; MES of Russia and NRC KI, Russian Federation; JINR; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DST/NRF, South Africa; MINECO, Spain; SRC and Wallenberg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TAEK, Turkey; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, the Canada Council, CANARIE, CRC, Compute Canada, FQRNT, and the Ontario Innovation Trust, Canada; EPLANET, ERC, FP7, Horizon 2020 and Marie Sklodowska-Curie Actions, European Union; Investissements d'Avenir Labex and Idex, ANR, Region Auvergne and Fondation Partager le Savoir, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF; BSF, GIF and Minerva, Israel; BRF, Norway; Generalitat de Catalunya, Generalitat Valenciana, Spain; the Royal Society and Leverhulme Trust, United Kingdom.The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN and the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA) and in the Tier-2 facilities worldwide
A randomized controlled trial reporting functional outcomes of cognitive-behavioural therapy in medication‑treated adults with ADHD and comorbid psychopathology

Studies assessing psychological treatment of attention deficit hyperactivity disorder (ADHD) in adults are increasingly reported. However, functional outcomes are often neglected in favour of symptom outcomes. We investigated functional outcomes in 95 adults with ADHD who were already treated with medication and randomized to receive treatment as usual (TAU/MED) or psychological treatment (CBT/MED) using a cognitive–behavioural programme, R&R2ADHD, which employs both group and individual modalities. RATE-S functional outcomes associated with ADHD symptoms, social functioning, emotional control and antisocial behaviour were given at baseline, end of treatment and three-month follow-up. The Total composite score of these scales is associated with life satisfaction. In addition, independent evaluator ratings of clinicians who were blind to treatment arm were obtained on the Clinical Global Impression scale at each time point. CBT/MED showed overall (combined outcome at end of treatment and 3-month follow-up) significantly greater functional improvement on all scales. Post-group treatment effects were maintained at follow-up with the exception of emotional control and the Total composite scales, which continued to improve. The largest treatment effect was for the RATE-S Total composite scale, associated with life satisfaction. CGI significantly correlated with all outcomes except for social functioning scale at follow-up. The study provides further evidence for the effectiveness of R&R2ADHD and demonstrates the importance of measuring functional outcomes. The key mechanism associated with improved functional outcomes is likely to be behavioural control
Cultural and Gender Convergence in Adolescent Drunkenness: Evidence From 23 European and North American Countries

OBJECTIVE: To investigate time-trend changes in the frequency of drunkenness among European and North American adolescents.
DESIGN: Cross-sectional surveys in the 1997/1998 and 2005/2006 Health Behaviour in School-Aged Children Study (HBSC).
SETTING: High schools in 23 countries.
PARTICIPANTS: A sample of 77 586 adolescents aged 15 years was analyzed by means of hierarchical linear modeling.
MAIN OUTCOME MEASURE: The frequency of drunkenness.
RESULTS: We observed a significant increase of about 40% in the mean frequency of drunkenness in all 7 participating Eastern European countries. This increase was evident among both genders, but most consistently among girls. Meanwhile, it declined in 13 of 16 Western countries, about 25% on average. Declines in Western countries were particularly notable among boys and in North America, Scandinavia, the United Kingdom, and Ireland. Despite this gender convergence, with few exceptions (Greenland, Norway, United Kingdom) boys continued to have a higher frequency of drunkenness in 2005/2006 than girls.
CONCLUSIONS: The confirmed cultural convergence implies that adoption and implementation of evidence-based measures to mitigate the frequency of adolescent drunkenness such as tax increases and restricting alcohol access and advertisement should get the same priority in Eastern European countries as in Western countries. Policy measures that might facilitate decreases in drunkenness such as server training and the promotion of alcohol-free leisure-time activities should be reinforced in Western countries. The gender convergence implies that prevention policy should be less exclusively focused on male adolescents
Ellipsoid Localisation Microscopy

Multi-layered protein coats are crucial to the dormancy, robustness, and germination of bacterial spores. In Bacillus subtilis spores the coat contains over 70 distinct proteins. Identifying which proteins reside in each layer may provide insight into their distinct functions. We present image analysis methods which determine the order and geometry of concentric protein layers by fitting a model description for a spheroidal fluorescent shell image to optical micrographs of spores incorporating fluorescent fusion proteins. The radius of a spherical protein shell can be determined more precisely than 10 nm by fitting an equation to widefield fluorescence micrographs. Ellipsoidal shell axes can be fitted with comparable precision. The layer orders inferred for B. subtilis and B. megaterium are consistent with measurements in literature. The aspect ratio of elongated spores and the tendency of some proteins to localise near their poles can be quantified, enabling measurement of structural anisotropy.We gratefully acknowledge support from MedImmune through the Beacon collaboration, the EPSRC Centre for Doctoral Training in Sensor Technologies and Applications (EP/L015889/1), and thank Clemens Kaminski, Romain Laine and Jose Casas-Finet for inspiring discussions.This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.bpj.2015.09.02
Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms

Progress in advancing a system-level understanding of the complexity of human tissue development and regeneration is hampered by a lack of biological model systems that recapitulate key aspects of these processes in a physiological context. Hence, growing demand by cell biologists for organ-specific extracellular mimics has led to the development of a plethora of 3D cell culture assays based on natural and synthetic matrices. We developed a physiological microenvironment of semisynthetic origin, called gelatin methacryloyl (GelMA)-based hydrogels, which combine the biocompatibility of natural matrices with the reproducibility, stability and modularity of synthetic biomaterials. We describe here a step-by-step protocol for the preparation of the GelMA polymer, which takes 1–2 weeks to complete, and which can be used to prepare hydrogel-based 3D cell culture models for cancer and stem cell research, as well as for tissue engineering applications. We also describe quality control and validation procedures, including how to assess the degree of GelMA functionalization and mechanical properties, to ensure reproducibility in experimental and animal studies
The NNLO QCD corrections to Z boson production at large transverse momentum

The transverse momentum distribution of massive neutral vector bosons can be measured to high accuracy at hadron colliders. The transverse momentum is caused by a partonic recoil, and is determined by QCD dynamics. We compute the single and double-differential transverse momentum distributions for fully inclusive $Z/\gamma^*$ production including leptonic decay to next-to-next-to-leading order (NNLO) in perturbative QCD. We also compute the same distributions normalised to the cross sections for inclusive $Z/\gamma^*$ production, i.e. integrated over the transverse momentum of the lepton pair. We compare our predictions for the fiducial cross sections to the 8 TeV data set from the ATLAS and CMS collaborations, which both observed a tension between data and NLO theory predictions, using the experimental cuts and binning. We find that the inclusion of the NNLO QCD effects does not fully resolve the tension with the data for the unnormalised $p^Z_T$ distribution. However, we observe that normalising the NNLO $Z$-boson transverse momentum distribution by the NNLO Drell-Yan cross section substantially improves the agreement between experimental data and theory, and opens the way for precision QCD studies of this observable