pinecone/core-2020-05-10-deduplication huggingface dataset:
Photon and neutral meson measurements with the ALICE experiment at the LHC

International audienceThe measurements of photons and neutral mesons, such as ?0 and ?, allow to explore the QCD matter created in heavy-ions collisions. In pp collisions, observables such as differential particle production cross sections can be used to test perturbative QCD calculations and constrain PDFs. In Pb-Pb collisions, neutral meson spectra address the medium induced suppression, whereas low transverse momentum direct photons allow to obtain information on the QCD medium temperature or anisotropic flow.We present an overview of photon and neutral meson measurements, employing three different methods which use both ALICE calorimeters, as well as the central tracking system via the photon conversion method. These experimental results are compared with theoretical predictions
ATLAS electromagnetic barrel calorimeter performance in recent testbeams

During the combined testbeam in summer 2004 a slice of the ATLAS barrel detector—including all detector sub systems from the inner tracker, the calorimetry to the muon system—was exposed to particle beams (electrons, pions, photons, muons) with different energies (1–350 GeV). The aim was to study the combined performance of the different detector sub systems in ATLAS-like conditions. We will present studies with different amounts of material in front of the calorimeter, representing various regions in the ATLAS detector, performance results from the electromagnetic calorimetry, including uniformity, resolution, and linearity as well as a discussion of the calibration scheme. The performance in the combined ATLAS-like set-up will be compared to the one obtained in stand-alone testbeams
Numerical validation of an Homogenized Interface Model

International audienceThe aim of this paper is to numerically validate the effectiveness of a matched asymptotic expansion formal method introduced in a pioneering paper by Nguetseng and Sànchez Palencia [1] and extended in [2], [3]. Using this method a simplified model for the influence of small identical heterogeneities periodically distributed on an internal surface to the overall response of a linearly elastic body is derived. In order to validate this formal method a careful numerical study compares the solution obtained by a standard method on a fine mesh to the one obtained by asymptotic expansion. We compute both the zero and the first order terms in the expansion. To efficiently compute the first order term we introduce a suitable domain decomposition method
Toward a timed theory of channel coding

International audienceThe classical theory of constrained-channel coding deals with the following questions: given two languages representing a source and a channel, is it possible to encode source messages to channel messages, and how to realize encoding and decoding by simple algorithms, most often transducers. The answers to this kind of questions are based on the notion of entropy. In the current paper, the questions and the results of the classical theory are lifted to timed languages. Using the notion of entropy of timed languages introduced by Asarin and Degorre, the question of timed coding is stated and solved in several settings
Leukotriene signaling in atherosclerosis and ischemia.

International audienceINTRODUCTION: The inflammatory process of atherosclerosis is associated with several pathophysiological reactions within the vascular wall. The arachidonic acid released by phospholipase A(2) serves as substrate for the production of a group of lipid mediators known as the leukotrienes, which induce pro-inflammatory signaling through activation of specific BLT and CysLT receptors. DISCUSSION: Leukotriene signaling has been implicated in early lipid retention and foam cell accumulation, as well as in the development of intimal hyperplasia and advanced atherosclerotic lesions. Furthermore, the association of leukotrienes with degradation of extracellular matrix has suggested a role in atherosclerotic plaque rupture. Finally, studies of either myocardial or cerebral ischemia and reperfusion indicate that leukotriene signaling in addition may be involved in the development of ischemic injury. CONCLUSION: Both leukotriene synthesis inhibitors and leukotriene receptor antagonists have been suggested to induce beneficial effects at different stages of the atherosclerosis process
XMapTools: A MATLAB©-based program for electron microprobe X-ray image processing and geothermobarometry

International audienceXMapTools is a MATLAB©-based graphical user interface program for electron microprobe X-ray image processing, which can be used to estimate the pressure-temperature conditions of crystallization of minerals in metamorphic rocks. This program (available online at http://www.xmaptools.com) provides a method to standardize raw electron microprobe data and includes functions to calculate the oxide weight percent compositions for various minerals. A set of external functions is provided to calculate structural formulae from the standardized analyses as well as to estimate pressure-temperature conditions of crystallization, using empirical and semi-empirical thermobarometers from the literature. Two graphical user interface modules, Chem2D and Triplot3D, are used to plot mineral compositions into binary and ternary diagrams. As an example, the software is used to study a high-pressure Himalayan eclogite sample from the Stak massif in Pakistan. The high-pressure paragenesis consisting of omphacite and garnet has been retrogressed to a symplectitic assemblage of amphibole, plagioclase and clinopyroxene. Mineral compositions corresponding to $165,000 analyses yield estimates for the eclogitic pressure-temperature retrograde path from 25 kbar to 9 kbar. Corresponding pressure- temperature maps were plotted and used to interpret the link between the equilibrium conditions of crystallization and the symplectitic microstructures. This example illustrates the usefulness of XMapTools for studying variations of the chemical composition of minerals and for retrieving information on metamorphic conditions on a microscale, towards computation of continuous pressure-temperature-and relative time path in zoned metamorphic minerals not affected by post-crystallization diffusion
Cost-Aware Early Classification of Time Series

International audienceIn time series classification, two antagonist notions are at stake. On the one hand, in most cases, the sooner the time series is classified , the more rewarding. On the other hand, an early classification is more likely to be erroneous. Most of the early classification methods have been designed to take a decision as soon as sucient level of reliability is reached. However, in many applications, delaying the decision with no guarantee that the reliability threshold will be met in the future can be costly. Recently, a framework dedicated to optimizing a trade-off between classification accuracy and the cost of delaying the decision was proposed, together with an algorithm that decides online the optimal time instant to classify an incoming time series. On top of this framework , we build in this paper two di↵erent early classification algorithms that optimize a trade-off between decision accuracy and the cost of delaying the decision. These algorithms are non-myopic in the sense that, even when classification is delayed, they can provide an estimate of when the optimal classification time is likely to occur. Our experiments on real datasets demonstrate that the proposed approaches are more robust than existing methods
Economic freedom in Muslim countries: an explanation using the theory of institutional path dependency

International audienceThis article explains the level of economic freedom in Muslim countries through the theory of institutional path dependency. Islamic countries are generally not free and they have a poor record regarding property rights. To explain these realities we use the institutional history of Muslim countries. We define three steps: the Arab and Ottoman Empires when Islamic law was of great importance, European colonisation, and the contemporary era with its movement towards a revival of Islam. Islamic law is not liberal. This explain why in general Muslim countries are not free. Colonisation radically changed institutional life in the twentieth century. British colonisation proved to be better than did French or Soviet colonisation. This explains why the Persian Gulf countries are freer. The collapse of the Soviet model explains the speed of liberalisation in former socialist countries (such as Albania, Kyrgyz Republic, and Kazakhstan). Nevertheless, the twentieth century was not just the century of Westernisation. It was also the century of the revival of Islam. The article concludes that the history of the twentieth century does not explain the way in which Muslim countries are attracted by the ideal of the Muslim city. The revival of Islamic intellectual innovations and the evolution of Muslim opinion sustain this thesis. Therefore, there is a dependency on the past and on an imagined future. Islam acts, like yesterday, on the world of institutional possibilities
Routine molecular profiling of cancer: results of a one-year nationwide program of the French Cooperative Thoracic Intergroup (IFCT) for advanced non-small cell lung cancer (NSCLC) patients.

International audienceBackground: The molecular profiling of patients with advanced non-small-cell lung cancer (NSCLC) for known oncogenic drivers is recommended during routine care. Nationally, however, the feasibility and effects on outcomes of this policy are unknown. We aimed to assess the characteristics, molecular profiles, and clinical outcomes of patients who were screened during a 1-year period by a nationwide programme funded by the French National Cancer Institute. Methods This study included patients with advanced NSCLC, who were routinely screened for EGFR mutations, ALK rearrangements, as well as HER2 (ERBB2), KRAS, BRAF, and PIK3CA mutations by 28 certified regional genetics centres in France. Patients were assessed consecutively during a 1-year period from April, 2012, to April, 2013. We measured the frequency of molecular alterations in the six routinely screened genes, the turnaround time in obtaining molecular results, and patients' clinical outcomes. This study is registered with ClinicalTrials.gov, number NCT01700582. Findings 18 679 molecular analyses of 17 664 patients with NSCLC were done (of patients with known data, median age was 64·5 years [range 18–98], 65% were men, 81% were smokers or former smokers, and 76% had adenocarcinoma). The median interval between the initiation of analysis and provision of the written report was 11 days (IQR 7–16). A genetic alteration was recorded in about 50% of the analyses; EGFR mutations were reported in 1947 (11%) of 17 706 analyses for which data were available, HER2 mutations in 98 (1%) of 11 723, KRAS mutations in 4894 (29%) of 17 001, BRAF mutations in 262 (2%) of 13 906, and PIK3CA mutations in 252 (2%) of 10 678; ALK rearrangements were reported in 388 (5%) of 8134 analyses. The median duration of follow-up at the time of analysis was 24·9 months (95% CI 24·8–25·0). The presence of a genetic alteration affected first-line treatment for 4176 (51%) of 8147 patients and was associated with a significant improvement in the proportion of patients achieving an overall response in first-line treatment (37% [95% CI 34·7–38·2] for presence of a genetic alteration vs 33% [29·5–35·6] for absence of a genetic alteration; p=0·03) and in second-line treatment (17% [15·0–18·8] vs 9% [6·7–11·9]; p&lt;0·0001). Presence of a genetic alteration was also associated with improved first-line progression-free survival (10·0 months [95% CI 9·2–10·7] vs 7·1 months [6·1–7·9]; p&lt;0·0001) and overall survival (16·5 months [15·0–18·3] vs 11·8 months [10·1–13·5]; p&lt;0·0001) compared with absence of a genetic alteration. Interpretation Routine nationwide molecular profiling of patients with advanced NSCLC is feasible. The frequency of genetic alterations, acceptable turnaround times in obtaining analysis results, and the clinical advantage provided by detection of a genetic alteration suggest that this policy provides a clinical benefit
Spodoptera frugiperda (Lepidoptera: Noctuidae) host-plant variants: two host strains or two distinct species?

International audienceThe moth Spodoptera frugiperda is a well-known pest of crops throughout the Americas, which consists of two strains adapted to different host-plants: the first feeds preferentially on corn, cotton and sorghum whereas the second is more associated with rice and several pasture grasses. Though morphologically indistinguishable, they exhibit differences in their mating behavior, pheromone compositions, and show development variability according to the host-plant. Though the latter suggest that both strains are different species, this issue is still highly controversial because hybrids naturally occur in the wild, not to mention the discrepancies among published results concerning mating success between the two strains. In order to clarify the status of the two host-plant strains of S. frugiperda, we analyze features that possibly reflect the level of post-zygotic isolation: (1) first generation (F1) hybrid lethality and sterility; (2) patterns of meiotic segregation of hybrids in reciprocal second generation (F2), as compared to the meiosis of the two parental strains. We found a significant reduction of mating success in F1 in one direction of the cross and a high level of microsatellite markers showing transmission ratio distortion in the F2 progeny. Our results support the existence of post-zygotic reproductive isolation between the two laboratory strains and are in accordance with the marked level of genetic differentiation that was recovered between individuals of the two strains collected from the field. Altogether these results provide additional evidence in favor of a sibling species status for the two strains
Safety, feasibility, and outcome results of cardiac resynchronization with triple-site ventricular stimulation compared to conventional cardiac resynchronization.

International audienceThe nonresponder rate to cardiac resynchronization therapy (CRT) may be due to incomplete resynchronization, with dyssynchrony persisting in approximately 30% of patients. We hypothesized that CRT with triple-site ventricular stimulation (TRIV) may improve resynchronization and its outcomes. The purpose of this study was to assess the feasibility and safety of TRIV and collected data on clinical outcomes to dimension future studies. Our pilot randomized trial was designed to assess the safety and feasibility of TRIV with 2 right ventricular leads and 1 left ventricular leads compared to conventional CRT. The primary end-point was the rate of severe adverse events at 6 months. Secondary end-points included functional improvement parameters, quality-of-life (QOL) score, and changes of echocardiographic indices at 6 and 12 months in a subset of patients. Seventy-six patients were enrolled at 11 centers and randomized to control or TRIV arm. All implant procedures but one were successful. At 6 months, there was no statistical difference between proportions of patients with at least 1 severe adverse event in both groups (34.1% vs 25.7%, P = .425). There also was no difference between functional improvement parameters, 6-minute walking distances (P = .40), QOL scores (P = .27), and echographic indices. At 12 months, the proportions of patients with a left ventricular ejection fraction gain of more than 5%, 10%, or 15% were significantly superior with TRIV. TRIV pacing is an effective and safe technique and may provide a greater benefit in ventricular remodeling than conventional CRT. Further studies are needed to assess its long-term benefit
Hennessy-Milner Logic with Greatest Fixed Points as a Complete Behavioural Specification Theory

International audienceThere are two fundamentally different approaches to specifying and verifying properties of systems. The logical approach makes use of specifications given as formulae of temporal or modal logics and relies on efficient model checking algorithms; the behavioural approach exploits various equivalence or refinement checking methods, provided the specifications are given in the same formalism as implementations. In this paper we provide translations between the logical formalism of Hennessy-Milner logic with greatest fixed points and the behavioural formalism of disjunctive modal transition systems. We also introduce a new operation of quotient for the above equivalent formalisms, which is adjoint to structural composition and allows synthesis of missing specifications from partial implementations. This is a substantial generalisation of the quotient for deterministic modal transition systems defined in earlier papers
The many-body Green function of degenerate systems

4 pages, 1 figureInternational audienceA rigorous non perturbative adiabatic approximation of the evolution operator in the many-body physics of degenerate systems is derived. This approximation is used to solve the long-standing problem of the choice of the initial states of H0 leading to eigenstates of H0+V for degenerate systems. These initial states are eigenstates of P0 V P0, where P0 is the projection onto a degenerate eigenspace of H0. This result is used to give the proper definition of the Green function, the statistical Green function and the non-equilibrium Green function of degenerate systems. The convergence of these Green functions is established
Experimental observation of strong light-matter coupling in ZnO microcavities: influence of large excitonic absorption

International audienceWe present experimental observation of the strong light-matter coupling regime in ZnO bulk microcavities grown on silicon. Angle resolved reflectivity measurements, corroborated by transfer-matrix simulations, show that Rabi splittings in the order of 70 meV are achieved even for low finesse cavities. The impact of the large excitonic absorption, which enables a ZnO bulk-like behavior to be observed even in the strong coupling regime, is illustrated both experimentally and theoretically by considering cavities with increasing thickness
Nonlinear Donati compatibility conditions for the nonlinear Kirchhoff -von K arm an-Love plate theory

International audienceLinear Donati compatibility conditions guarantee that the components of symmetric tensor fields are those of linearized change of metric or linearized change of curvature tensor fields associated with the displacement vector field arising in a linearly elastic structure when it is subjected to applied forces. These compatibility conditions take the form of variational equations with divergence-free tensor fields as test-functions, by contrast with Saint-Venant compatibility conditions, which take the form of systems of partial differential equations. In this paper, we identify and justify nonlinear Donati compatibility conditions that apply to a nonlinearly elastic plate modeled by the Kirchhoff-von K'arm'an-Love theory
Growth rate for the expected value of a generalized random Fibonacci sequence

International audienceA random Fibonacci sequence is defined by the relation g_n = | g_{n-1} +/- g_{n-2} |, where the +/- sign is chosen by tossing a balanced coin for each n. We generalize these sequences to the case when the coin is unbalanced (denoting by p the probability of a +), and the recurrence relation is of the form g_n = |\lambda g_{n-1} +/- g_{n-2} |. When \lambda >=2 and 0 < p <= 1, we prove that the expected value of g_n grows exponentially fast. When \lambda = \lambda_k = 2 cos(\pi/k) for some fixed integer k>2, we show that the expected value of g_n grows exponentially fast for p>(2-\lambda_k)/4 and give an algebraic expression for the growth rate. The involved methods extend (and correct) those introduced in a previous paper by the second author
Surface displacements on faults triggered by slow magma transfers between dyke injections in the 2005–2010 rifting episode at Dabbahu–Manda–Hararo rift (Afar, Ethiopia)

International audienceThe rifting episode that occurred in Dabbahu–Manda–Hararo (Ethiopia) between 2005 and 2010 during which 14 dyke intrusions were emitted, was a unique opportunity to study interactions between tectonic deformation and magmatic processes. While magmatism has been shown to control primarily the spatial and temporal distribution of dyke intrusions during this accretion sequence, the role of faults in accommodating plate spreading in rift segments is poorly understood. During interdyking periods, transient ground deformation due to magma movement is generally observed. Investigating such a small-scale deformation and in particular the movement along faults during these periods will help understanding the factors that trigger fault movement in magmatic rifts. We analyse fault activity during three interdyking periods: 2006 December–June (d0–d1), 2007 January–July (d5–d6) and 2009 November–January (d10– d11). The time–space evolution of surface displacements along ∼700 faults is derived from pairs of ascending and descending SAR interferograms. Surface slip distributions are then compared with codyking ground deformation fields. The results show that faults are mainly activated above the areas affected by magma emplacement during interdyking periods. A detailed analysis of brittle deformation during the six months following the 2005 September intrusion shows asymmetric deformation on the rift shoulders, with significant opening on faults located to the west of the dyke. We explain this feature by the activation of westward dipping pre-existing faults, with block rotations in between. In addition, we observe that the strip encompassing the activated faults narrows by 30 per cent from co-to interdyking period. This suggests that magma keeps migrating to shallower depths after the dyke intrusion. During a rifting episode, activation of faults in a pre-existing fracture network therefore seems to be mainly controlled by deep magma processes
Measurement and modelling of dew in island, coastal and alpine areas

International audienceWe compare the characteristics of dew at nearly the same latitude (42 – 45jN) for the Mediterranean island of Corsica (Ajaccio, France) and two continental locations (Bordeaux, France, Atlantic coastal area; Grenoble, France, alpine valley). Dew amount was measured on a horizontal reference plate made of polymethylmethacrylate (PMMA) and placed at 1 m above the ground. Data are correlated with plate and air temperature, air relative humidity, wind speed and cloud cover during the period from 14-08-1999 to 15-01-2003. General features as well as particularities of the sampling sites are discussed. The average daily dew yield is higher for the island station at Ajaccio (0.070 mm) than the Bordeaux coastal area (0.046 mm) or the Grenoble valley (0.036 mm). However, the accumulated dew yield was highest for the coastal station (9.8 mm/year) as compared to the island (8.4 mm/year), and much larger than in the alpine valley (4 mm/year). The difference between cumulated and average dew yield stems from the greater number of dew days in the coastal area (58%) versus 33% for the island and 30% in the valley. The higher wind speeds at the island station (average wind during dew is 2 m/s) and lower relative humidity explain the smaller number of dew days. The dew rate seasonal variation is negligible in Bordeaux and exhibits during summer a maximum in Ajaccio and a minimum in Grenoble. A computer model that includes simple meteorological data (air temperature and relative humidity, wind speed, cloud cover) is used to determine the thermal balance and fit to dew mass evolution. Two parameters that account for heat and mass exchange can be adjusted. It was found that, within the uncertainties, these two numbers are the same for the two continental sites, thus allowing dew formation on plates to be evaluated from only simple meteorological measurements. Somewhat larger values are found for the island, due to limitations in the model, which are discussed