pinecone/core-2020-05-10-deduplication huggingface dataset:
DYNAMIC CROSS-LAYER SPECTRUM ALLOCATION FOR MULTI-BAND HIGH-RATE UWB SYSTEMS

ISBN: 978-90-481-2529-6International audienceIn this paper, we investigate a new approach for the spectrum allocation in UWB systems. This approach consists in a cross-layer scheme that takes into consideration the different users channel quality and quality of service (QoS) requirements. The new scheme is based on the WiMedia solution proposed for multiband OFDM UWB systems. The main objective is to propose a low-complexity solution for the spectrum allocation that can manage all the users constraints. Thus, we study the optimal solution of the spectrum allocation and formulate it as a convex optimization problem. Then, we show that our proposed scheme reduces significantly the complexity of the optimal solution. Moreover, we show through simulations, that the new approach and the optimal solution have close performance in term of error rate and they outperform WiMedia solution proposed for UWB systems
Natural hazards versus climate change and their potential impacts in the dry, northern Himalayas: focus on the upper Kali Gandaki (Mustang District, Nepal)

Special Issue : Sustainable Water Management in Central Asia .International audienceIn the Himalayas, the consequences of climate change are a fairly debated issue, mainly questioning the availability of water resources to the lowland population. North of the monsoon Himalayas, a semi-arid, continental climate prevails and settlements rely economically mostly on irrigated crops, high altitude rangelands, trade and tourism. The upper Kali Gandaki (Mustang) is situated in this area, with sharp contrasts between valley bottoms (\3,000 m) and high, glaciated peaks (up to [8,000 m). The impacts of climate change may appear in different ways. Gullying is common, and might increase with greater climate variability. Increased ground instabilities (earth-flows and occasional debris flows) affecting extensive shale/marly substrates are also expected, linked to changes in snow cover and seasonality. Similarly, the combination of higher snowfall and rapid melting may favour the occurrence of flash floods. The possibility of glacial outburst floods is less probable because of the present limited glaciation. Eventually, permafrost melting may induce rock avalanches down the steepest cliffs and might impact the adjacent valley floors. Collectively, these hazards will affect irrigation canals and fields, new infrastructures and the associated growing settlements. Water availability in the near future is more difficult to predict; however, any change in the amount and nature of precipitation may affect groundwater reserves, hence spring discharge and runoff, with consequences for agricultural products. Eventually, the overall potential increase in natural hazards may jeopardize the development of small markets and the good connection of these upper valleys to the main urban centres of Nepal, a country with a very low economic and social capacity to adjust
The role of daily mobility in mental health inequalities: the interactive influence of activity space and neighbourhood of residence on depression.
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The interactive influence of activity space and neighbourhood of residence on depression.

International audienceThe literature reports an association between neighbourhood deprivation and individual depression after adjustment for individual factors. The present paper investigates whether vulnerability to neighbourhood features is influenced by individual "activity space" (i.e., the space within which people move about or travel in the course of their daily activities). It can be assumed that a deprived residential environment can exert a stronger influence on the mental health of people whose activity space is limited to their neighbourhood of residence, since their exposure to their neighbourhood would be greater. Moreover, we studied the relationship between activity space size and depression. A limited activity space could indeed reflect spatial and social confinement and thus be associated with a higher risk of being depressed, or, conversely, it could be linked to a deep attachment to the neighbourhood of residence and thus be associated with a lower risk of being depressed. Multilevel logistic regression analyses of a representative sample consisting of 3011 inhabitants surveyed in 2005 in the Paris, France metropolitan area and nested within 50 census blocks showed, after adjusting for individual-level variables, that people living in deprived neighbourhoods were significantly more depressed that those living in more advantaged neighbourhoods. We also observed a statistically significant cross-level interaction between activity space and neighbourhood deprivation, as they relate to depression. Living in a deprived neighbourhood had a stronger and statistically significant effect on depression in people whose activity space was limited to their neighbourhood than in those whose daily travels extended beyond it. In addition, a limited activity space appeared to be a protective factor with regard to depression for people living in advantaged neighbourhoods and a risk factor for those living in deprived neighbourhoods. It could therefore be useful to take activity space into consideration more often when studying the social and spatial determinants of depression
Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice

International audienceMore than 50% of patients with advanced stages of colon cancer suffer from progressive loss of skeletal muscle, called cachexia, resulting in reduced quality of life and shortened survival. It is becoming evident that reactive oxygen species (ROS) regulate pathways controlling skeletal muscle atrophy. Herein we tested the hypothesis that antioxidant supplementation could prevent skeletal muscle atrophy in a model of cachectic Colon 26 (C26) tumor-bearing mice. Seven-week-old BALB/c mice were subcutaneously inoculated with colon 26 (C26) cancer cells or PBS. Then C26-mice were daily gavaged during 22 days either with PBS (vehicle) or an antioxidant cocktail whose composition is close to that of commercial dietary antioxidant supplements (rich in catechins, quercetin and vitamin C). We found that antioxidants enhanced weight loss and caused premature death of mice. Antioxidants supplementation failed to prevent (i) the increase in plasma TNF-α levels and systemic oxidative damage, (ii) skeletal muscle atrophy and (iii) activation of the ubiquitin-proteasome system (MuRF-1, MAFbx and polyubiquitinated proteins). Accordingly, immunohistological staining for Ki-67 and the expression of cell cycle inhibitors demonstrated that tumor of supplemented mice developed faster with a concomitant decrease in oxidative damage. Previous studies have shown that the use of catechins and quercetin separately can improve the musculoskeletal function in cachectic animals. However, our results indicate that the combination of these antioxidants reduced survival and enhanced cachexia in C26-mice
VLT/NACO infrared adaptive optics images of small scale structures in OMC1

International audienceNear-infrared observations of line emission from excited H 2 and in the continuum are reported in the direction of the Orion molecular cloud OMC1 , using the European Southern Observatory Very Large Telescope UT4 , equipped with the NAOS adaptive optics system on the CONICA infrared array camera. Spatial resolution has been achieved at close to the diffraction limit of the telescope (0. 08 −0. 12) and images show a wealth of morphological detail. Structure is not fractal but shows two preferred scale sizes of 2. (1100 AU) and 1. 2 (540 AU) , where the larger scale may be associated with star formation. Key words. ISM : individual objects : OMC1 – ISM : circumstellar matter – ISM : kinematics and dynamics – ISM : molecules – infrared : IS
Climate and human development impacts on municipal water demand: A spatially-explicit global modeling framework

Municipal water systems provide crucial services for human well-being, and will undergo a major transformation this century following global technological, socioeconomic and environmental changes. Future demand scenarios integrating these drivers over multi-decadal planning horizons are needed to develop effective adaptation strategies. This paper presents a new long-term scenario modeling framework that projects future daily municipal water demand at a 1/8° global spatial resolution. The methodology incorporates improved representations of important demand drivers such as urbanization and climate change. The framework is applied across multiple future socioeconomic and climate scenarios to explore municipal water demand uncertainties over the 21st century. The scenario analysis reveals that achieving a low-carbon development pathway can potentially reduce global municipal water demands in 2060 by 2–4%, although the timing and scale of impacts vary significantly with geographic location
Experimental and numerical investigation on carbonitrided steel characterization with spherical indentation

International audienceThis study investigates the mechanical behavior of a carbonitrided steel, plastically graded material, during a spherical indentation test. We demonstrate that the behavior of a carbonitrided steel can be simulated accurately with a seven layer sample, including the surface, five intermediate layers and the substrate. Moreover, for engineering design simulations which require a lot of calculation time, using three layers provides a good compromise for accuracy. A complete experimental procedure involving seven successive identifications with inverse analysis gave the same results as a simpler procedure proposed in a previous paper. It is shown that the assumption of a linear variation of the properties in the intermediate layers between surface and substrate is valid. This is the first time that an instrumented roller indentation test has demonstrated the reliability of the proposed method for the mechanical characterization of carbonitrided steels with spherical indentation
Power Management in Grid Computing with Xen

International audienceWhile chip vendor still stick to Moore's law, and the performance per dollar keeps going up, the performance per watt has been stagnant for the last few years. Moreover energy prices continue to rise world-wide. This poses a major challenge to organisations running grids, indeed such architectures require cooling systems. Indeed the one-year cost of a cooling system and of the power consumption may outfit the grid initial investement. We observe , however, that a grid does not constantly run at peak performance. In this paper, we propose a workload concentration strategy to reduce grid power consumption. Using the Xen virtual machine migration technology, our power management policy can dispatch transparently and dynamically any applications of the grid. Our policy concentrates the workload to shutdown nodes that are unused with a neglectable impact on performance. We show through evaluations that this policy decreases the overall power consumption of the grid significantl
The Unified Enterprise Modelling Language – Overview and further work

International audienceThe Unified Enterprise Modelling Language (UEML) aims at supporting integrated use of enterprise and IS models expressed using different languages. To achieve this aim, UEML offers a hub through which modelling languages can be connected, thereby paving the way for also connecting the models expressed in those languages. This paper motivates and presents the most central parts of the UEML approach: a structured path to describing enterprise and IS modelling constructs; a common ontology to interrelate construct descriptions at the semantic level; a correspondence analysis approach to estimate semantic construct similarity; a quality framework to aid selection of languages; a meta-meta model to integrate the different parts of the approach; and a set of tools to aid its use and evolution. The paper also discusses the benefits of UEML and points to paths for further work
Structure of the iron-binding exopolysaccharide produced anaerobically by the Gram-negative bacterium Klebsiella oxytoca BAS-10.

Klebsiella oxytoca BAS-10 is a Gram-negative micro-organism
capable of growing on high concentrations of heavy metals.
This bacterium produces large amounts of an iron-binding
exopolysaccharide that, in the presence of metallic cations,
precipitates as a dense gel. The primary and secondary
structure of the repeating unit of such polysaccharide has
been characterised by chemical and spectroscopic methods,
resulting in the following heptasaccharide: 2)-α-Rha-(1_3)-
β-Gal-(1_2)-α-Rha-(1_4)-β-GlcA-[β-GlcA-(1_4)]-(1_3)-α-
Rha-(1_3)-α-Rha-(1_. The absolute configurations for the
Rha units are L, while those for the GlcA and Gal residues
are D
1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

International audienceAutism Spectrum Disorders (ASD) are a group of developmental disorders caused by environmental and genetic factors. Diagnosis is based on behavioral and developmental signs detected before 3 years of age with no reliable biological marker. The purpose of this study was to evaluate the potential use of a 2D NMR-based approach to express the global biochemical signature of autistic individuals compared to normal controls. This technique has greater spectral resolution than to 1D (1)H NMR spectroscopy, which is limited by overlapping signals. The urinary metabolic profiles of 30 autistic and 28 matched healthy children were obtained using a (1)H-(13)C NMR-based approach. The data acquired were processed by multivariate orthogonal partial least-squares discriminant analysis (OPLS-DA). Some discriminating metabolites were identified: β-alanine, glycine, taurine and succinate concentrations were significatively higher, and creatine and 3-methylhistidine concentrations were lower in autistic children than in controls. We also noted differences in several other metabolites that were unidentified but characterized by a cross peak correlation in (1)H-(13)C HSQC. Statistical models of (1)H and (1)H-(13)C analyses were compared and only 2D spectra allowed the characterization of statistically relevant changes [R(2)Y(cum)=0.78 and Q(2)(cum)=0.60] in the low abundance metabolites. This method has the potential to contribute to the diagnosis of neurodevelopment disorders but needs to be validated on larger cohorts and on other developmental disorders to define its specificity
Stress Intensity Factor for a Circumferential Crack in a Finite-Length Thin to Thick Walled Cylinder under an Arbitrary Biquadratic Stress Distribution on the Crack Surfaces

This paper presents the development of a practical method, by using prepared tabulated data, to
calculate the mode I stress intensity factor (SIF) for an inner surface circumferential crack in a finite
length cylinder. The crack surfaces are subjected to an axisymmetric stress with an arbitrary biquadratic
radial distribution. The method was derived by applying the authors’ weight function for the crack. This
work is based on the thin shell theory and the Petroski-Achenbach method. Our method is valid over a
wide range of mean radius to wall thickness ratio, Rm/W ≥ 1, and for relatively short cracks with a/W ≤
0.5. The difference between the SIF obtained by our method for the geometry and that from finite element
analysis is within 5%. The method we developed describes the effect that cylinder length gives on the SIF.
This effect needs to be considered for cylinders shorter than non-dimensional cylinder length βH≤ 5
Stable-isotope dilution gas chromatography–mass spectrometric measurement of 3-hydroxyglutaric acid, glutaric acid and related metabolites in body fluids of patients with glutaric aciduria type 1 found in newborn screening

We developed a simple and sensitive stable-isotope dilution method for the quantification of 3-hydroxyglutaric acid (3HGA) and glutaric acid (GA) in body fluids. In our method, tert-butyldimethylsilyl (tBDMS) derivatives of 3HGA and GA were measured with a conventional electron-impact ionization (EI) mode in gas chromatography–mass spectrometry (GC–MS). The control values for 3HGA in nmol/ml were 0.15 ± 0.08 (serum; n = 10) and 0.07 ± 0.03 (CSF; n = 10). In addition, glutarylcarnitine and free carnitine were quantified by electrospray tandem mass spectrometry. Using these methods, we monitored 3HGA, GA, and glutarylcarnitine in the body fluids of three patients with glutaric aciduria type 1 found during newborn screening. None of the patients had experienced neurological strokes, which are possibly caused by the accumulation of 3HGA, at 15–24 months of age under a disease-specific treatment, including carnitine supplementation. Our data showed that 3HGA levels were relatively high in some serum samples with lower glutarylcarnitine and carnitine levels, suggesting that carnitine supplementation may play a role in preventing the accumulation of 3HGA in patients with this disease
Electrochemically instantaneous reduction of conducting polyaniline-coated latex particles dispersed in acidic solution

A cathodic voltammetric wave was observed in an aqueous suspension of
	mono-dispersed, spherical polyaniline-coated polystyrene particles, whereas no anodic
	wave was detected. This irreversibility was common to particles with eight different
	diameters ranging from 0.2 to 7.5 μm. Such irreversibility cannot be found at
	polyaniline-coated electrodes, and thus is a property of the dispersion of polyaniline
	latex. The reduction current was controlled by diffusion of dispersed particles. The
	reduction, being the conversion from the electrical conducting state to the resistive one,
	should begin at a point of contact between the conducting particle and the electrode in
	order to be propagated to the whole particle rapidly. In contrast, the oxidation proceeds
	slowly with the propagation of conducting zone, during which Brownian motion lets the
	particle detach from the electrode. The number of loaded aniline units per particle,
	determined by weight analysis, ranged from 6×10_6 (φ 0.2 μm) to 3×10_11 (φ 7.5 μm) and
	was proportional to 2.9 powers of the particle diameter. The diffusion-controlled current
	of the cathodic wave was proportional to 2.4 powers of the diameter. The difference in
	these powers, 0.5, agreed with a theoretical estimation of the diffusion-controlled
	current, the diffusion coefficient for which was given by the Stokes-Einstein equation
Adsorption Force of Polyaniline-Coated Polystyrene Latex Particles

Visible polyaniline-latex particles 13 μm in diameter were used for obtaining quantitatively a relationship between the adsorption force and the electroactivity at a platinum electrode. The suspension in hydrochloride acid was filled in an optical cell equipped with wire electrodes. When electrode potential was switched between the oxidized and the reduced domains alternatively, some adsorbed particles showed color change owing to the electroactivity. The numbers of the electroactive and the inactive particles were counted in the suspension including poly(N-vinylpyrrolidone) (PVP). The ratio of the numbers was proportional to the concentration of PVP, as was in equilibrium. The adsorbed particles were desorbed mechanically by forced flow. The numbers of the desorbed particles did not decrease with an increase in the flow velocity until threshold values. The threshold value for the electroactive particle was 10 times larger than that for the inactive ones, corresponding to 10 times larger adsorption energy of the electroactive particles than the inactive ones. The adsorption stress was evaluated from the removal of the electropolymerized polyaniline film from the electrode. Then the adsorption area of the particle was estimated
Diffusion-controlled current with memory

The diffusion equation complicated by a delay of a concentration flux, J, from the formation of a concentration gradient, ∂c/∂x, was formulated in the context of electrochemical measurements. In contrast with the Fick’s first law, J = -D∂c/∂x, the flux at a short time is known to be delayed owing to a finite propagation speed of the gradient, called the memory effect or the second sound for thermal diffusivity. The modified Fick’s law contained the second time-derivative of the concentration multiplied by the relaxation time, τ, additive to the conventional diffusion equation. It was applied to chronoamperometry. The current-time curve was smoother than that for the Cottrell equation. The current at a short time was almost constant owing to the rate-determining step of the propagation velocity, (D/τ)1/2, and then decays obeying the Cottrell equation. This variation was similar to the curve mixed with the Butler-Volmer kinetics. The relaxation time was estimated from the period during which a diffusing particle can recognize the concentration gradient by collision with the nearest diffusing particle. The propagation velocity was of the order of some cm s-1, which is similar to the maximum values of the measurable charge transfer rate constant
Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells: Two-Year Follow-up Results

Producción CientíficaOsteoarthritis is the most prevalent
joint disease and a frequent cause
of joint pain, functional loss, and disability
(1). Osteoarthritis often becomes
chronic, and conventional treatments
have demonstrated only modest clinical
benefits, without lesion reversal (2). Cellbased
therapies have shown encouraging
results in both animal studies and a
few human case reports.We have recently
published the results of a pilot clinical
trial designed to assess the feasibility
and safety of osteoarthritis treatment
with bone marrowYderived mesenchymal
stromal cells (MSCs) in 12 patients
with chronic knee pain unresponsive
to conservative treatments and radiologic
evidence of osteoarthritis (3). The
patients were treated with autologous
expanded bone marrow MSCs by intraarticular
injection (40 106 cells), and
clinical outcomes, including evaluations
of pain, disability, and quality of life, were
followed up for 1 year. Articular cartilage
quality was assessed by quantitative
magnetic resonance imaging (MRI) T2
mapping (3).2015-09-3
The sport participation legacy of the Sydney 2000 Olympic Games and other international sporting events hosted in Australia

The legacy of an Olympic Games in a host city or country can take a variety of forms, including non-sporting benefits, such as enhanced urban infrastructure and national and international tourism profile, and sporting benefits, such as improved sporting facilities, strengthened sports organisations and potential increases in grassroots sport participation. This paper concentrates on the last of these, particularly in regard to the Sydney 2000 Olympic Games. The paper examines claims by the Olympic movement concerning increased sports participation as a legacy and examines available evidence to consider whether the hosting of the Games boosted sports participation in Australia. While some estimates suggest that participation did increase following the hosting of the 2000 Olympics, the failure of relevant organisations to maintain an adequate and consistent data collection regime makes this conclusion extremely speculative. From 2001 onwards, with the existence of a more stable data collection system and increasing awareness of the idea of a sport participation legacy, it is possible to make more reliable estimates of the pattern of grassroots sports participation following the hosting of the 2003 Rugby World Cup and the 2006 Melbourne Commonwealth Games. However, even when reliable and consistent participation data are available, the question of causality in the context of the wider sport development and participation system remains to be addressed