pinecone/core-2020-05-10-deduplication huggingface dataset:
Early relationship struggles: A case study of alliance formation and reparation

Aim: A good alliance established during the early sessions of psychotherapy will most likely lead to a good outcome. As a result, there is much to learn from a case in which both the patient and therapist regarded the alliance as being poor for an extended period (the first 15 sessions), yet still managed to develop a solid and stable alliance and reach a successful completion of therapy. The aim is to give a close inspection of this reparation process. Methods and analysis: Ratings on the Working Alliance Inventory (WAI) were used to guide the strategic selection of a case in which a depressed woman in her thirties sought help from an experienced senior male psychotherapist. A detailed analysis of the therapeutic dialogue brought forth what the parties expected from each other and how they responded to explicit and implicit expressions about how to proceed. Post-termination interviews revealed their subjective configurations of events in therapy and their corresponding reflections. Findings and discussion: Important steps and hallmarks of the alliance formation and reparation were identified: (i) Early in the process, incompatible expectations about what the relationship could achieve led to repetitious struggles. (ii) Their conflicting notions came forward in a more open dialogue about two specific issues (her medication and sick leave). (iii) Through the recognition of different viewpoints they were able to expand on their interactional pattern and develop playful ways to explore her decision making in everyday life. (iv) Temporary breaks seemed to consolidate her autonomy. (v) Late in the course of therapy, the therapist introduced a literary metaphor that seemed to further consolidate the alliance.<br><br>

This is an Author's Accepted Manuscript of an article published in British Association for Counselling and Psychotherapy, available onlin
Psychometric validation of the revised family affluence scale : a latent variable approach

The aim was to develop and test a brief revised version of the family affluence scale. A total of 7120 students from Denmark, Greenland, Italy, Norway, Poland, Romania, Scotland and Slovakia reported on a list of 16 potential indicators of affluence. Responses were subject to item screening and test of dimensionality. Bifactor analysis revealed a strong general factor of affluence in all countries, but with additional specific factors in all countries. The specific factors mainly reflected overlapping item content. Item screening was conducted to eliminate items with low discrimination and local dependence, reducing the number of items from sixteen to six: Number of computers, number of cars, own bedroom, holidays abroad, dishwasher, and bathroom. The six-item version was estimated with Samejima’s graded response model, and tested for differential item functioning by country. Three of the six items were invariant across countries, thus anchoring the scale to a common metric across countries. The six-item scale correlated with parental reported income groups in six out of eight countries. Findings support a revision to six items in the family affluence scale.Publisher PDFPeer reviewe
Recognition of the ligand-type specificity of classical and non-classical MHC I proteins.

Functional characterization of proteins belonging to the MHC I superfamily involves knowing their cognate ligands, which can be peptides, lipids or none. However, the experimental identification of these ligands is not an easy task and generally requires some a priori knowledge of their chemical nature (ligand-type specificity). Here, we trained k-nearest neighbor and support vector machine classifiers that predict the ligand-type specificity MHC I proteins with great accuracy. Moreover, we applied these classifiers to human and mouse MHC I proteins of uncharacterized ligands, obtaining some results that can be instrumental to unravel the function of these proteins
Insights into the High-energy gamma-ray emission of Markarian 501 from extensive multifrequency observations in the Fermi Era

We report on the gamma-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) gamma-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 ± 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 ± 0.14, and the softest one is 2.51 ± 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15—August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size ~&lt; 0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (~=10^44 erg s^–1) constitutes only a small fraction (~10^–3) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude
Efficient frequent connected subgraph mining in graphs of bounded treewidth

The frequent connected subgraph mining problem, i.e., the problem
of listing all connected graphs that are subgraph isomorphic to at least
a certain number of transaction graphs of a database, cannot be solved
in output polynomial time in the general case. If, however, the transaction
graphs are restricted to forests then the problem becomes tractable.
In this paper we generalize the positive result on forests to graphs of
bounded treewidth. In particular, we show that for this class of transaction
graphs, frequent connected subgraphs can be listed in incremental
polynomial time. Since subgraph isomorphism remains NP-complete for
bounded treewidth graphs, the positive complexity result of this paper
shows that efficient frequent pattern mining is possible even for computationally
hard pattern matching operators.status: publishe
A ( 2+1 ) non-commutative Drinfel'd double spacetime with cosmological constant

We show that the Drinfel'd double associated to the standard quantum deformation slη(2,ℝ) is isomorphic to the (2+1) -dimensional AdS algebra with the initial deformation parameter η related to the cosmological constant Λ=−η2 . This gives rise to a generalisation of a non-commutative Minkowski spacetime that arises as a consequence of the quantum double symmetry of (2+1) gravity to non-vanishing cosmological constant. The properties of the AdS quantum double that generalises this symmetry to the case Λ≠0 are sketched, and it is shown that the new non-commutative AdS spacetime is a nonlinear Λ -deformation of the Minkowskian one
A non-trivial zero length limit of the Nambu–Goto string

We show that a Nambu–Goto string has a nontrivial zero length limit which corresponds to a massless particle with extrinsic curvature. The system has the set of six first class constraints, which restrict the phase space variables so that the spin vanishes. Upon quantization, we obtain six conditions on the state, which can be represented as a wave function of position coordinates, xμ , and velocities, qμ . We have found a wave function ψ(x,q) that turns out to be a general solution of the corresponding system of six differential equations, if the dimensionality of spacetime is eight. Although classically the system is just a point particle with vanishing extrinsic curvature and spin, the quantized system is not trivial, because it is consistent in eight, but not in arbitrary, dimensions
IR fixed points in SU(3) gauge theories

We propose a novel RG method to specify the location of the IR fixed point in lattice gauge theories and apply it to the SU(3) gauge theories with Nf fundamental fermions. It is based on the scaling behavior of the propagator through the RG analysis with a finite IR cutoff, which we cannot remove in the conformal field theories in sharp contrast to the confining theories. The method also enables us to estimate the anomalous mass dimension in the continuum limit at the IR fixed point. We perform the program for Nf=16,12,8 and Nf=7 and indeed identify the location of the IR fixed points in all cases
Resonant Amplification of Gauge Fields in Expanding Universe

We investigate the possibility that gauge fluctuations are amplified in an
expanding universe by parametric resonance, during the oscillatory regime of a
scalar field to which they are coupled. We investigate the couplings of gauge
fields to a charged scalar field and to an axion. For both couplings, gauge
field fluctuations undergo exponential instabilities. We discuss how the
presence of other charges or currents may counteract the resonance, but we
argue that in some cases the resonance will persist and that hence this
mechanism could have some relevance for the problem of large scale primordial
magnetic fields
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field.We conducted a genome-wide association study (GWAS) and a follow-up study of bipolar disorder (BD), a common neuropsychiatric disorder. In the GWAS, we investigated 499,494 autosomal and 12,484 X-chromosomal SNPs in 682 patients with BD and in 1300 controls. In the first follow-up step, we tested the most significant 48 SNPs in 1729 patients with BD and in 2313 controls. Eight SNPs showed nominally significant association with BD and were introduced to a meta-analysis of the GWAS and the first follow-up samples. Genetic variation in the neurocan gene (NCAN) showed genome-wide significant association with BD in 2411 patients and 3613 controls (rs1064395, p = 3.02 × 10(-8); odds ratio = 1.31). In a second follow-up step, we replicated this finding in independent samples of BD, totaling 6030 patients and 31,749 controls (p = 2.74 × 10(-4); odds ratio = 1.12). The combined analysis of all study samples yielded a p value of 2.14 × 10(-9) (odds ratio = 1.17). Our results provide evidence that rs1064395 is a common risk factor for BD. NCAN encodes neurocan, an extracellular matrix glycoprotein, which is thought to be involved in cell adhesion and migration. We found that expression in mice is localized within cortical and hippocampal areas. These areas are involved in cognition and emotion regulation and have previously been implicated in BD by neuropsychological, neuroimaging, and postmortem studies
ネクロスタチン-1は活性酸素種による急性アセトアミノフェン肝障害に対して防御的に働く

Kenji Takemoto, Etsuro Hatano, Keiko Iwaisako, Masatoshi Takeiri, Naruto Noma, Saori Ohmae, Kan Toriguchi, Kazutaka Tanabe, Hirokazu Tanaka, Satoru Seo, Kojiro Taura, Keigo Machida, Norihiko Takeda, Shigehira Saji, Shinji Uemoto, Masataka Asagiri, Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure, FEBS Open Bio, Volume 4, 2014, Pages 777-787, ISSN 2211-5463Kyoto University (京都大学)0048新制・課程博士博士(医学)甲第18678号医博第3950号新制||医||1007(附属図書館)31611京都大学大学院医学研究科医学専攻(主査)教授 松原 和夫, 教授 渡邊 直樹, 教授 一山 智学位規則第4条第1項該
Changing system interfaces consistently: A new refinement strategy for CSP||B

This paper is concerned with event refinement in the context of CSP‖B. Our motivation to include this notion within the CSP‖B framework is the desire to increase flexibility in the refinement process. This approach provides the ability to change the events of CSP processes and B machines when refining a system. Notions of refinement based on traces and on traces/divergences allow abstract events to be refined by sequences of concrete events. A complementary notion of refinement between B machines is also proposed, yielding compositionality results for refinement of CSP‖B controlled components. The paper also introduces a notion of I/O refinement into our event refinement framework
A motivating exploration on lunar craters and low-energy dynamics in the Earth–Moon system

It is known that most of the craters on the surface of the Moon were created by\ud
the collision of minor bodies of the Solar System. Main Belt Asteroids, which can approach\ud
the terrestrial planets as a consequence of different types of resonance, are actually the main\ud
responsible for this phenomenon. Our aim is to investigate the impact distributions on the\ud
lunar surface that low-energy dynamics can provide. As a first approximation, we exploit the\ud
hyberbolic invariantmanifolds associated with the central invariantmanifold around the equilibrium\ud
point L2 of the Earth–Moon system within the framework of the Circular Restricted\ud
Three-Body Problem. Taking transit trajectories at several energy levels, we look for orbits\ud
intersecting the surface of the Moon and we attempt to define a relationship between longitude\ud
and latitude of arrival and lunar craters density. Then, we add the gravitational effect of\ud
the Sun by considering the Bicircular Restricted Four-Body Problem. In the former case, as\ud
main outcome, we observe amore relevant bombardment at the apex of the lunar surface, and\ud
a percentage of impact which is almost constant and whose value depends on the assumed\ud
Earth–Moon distance dEM. In the latter, it seems that the Earth–Moon and Earth–Moon–\ud
Sun relative distances and the initial phase of the Sun θ0 play a crucial role on the impact\ud
distribution. The leading side focusing becomes more and more evident as dEM decreases\ud
and there seems to exist values of θ0 more favorable to produce impacts with the Moon.\ud
Moreover, the presence of the Sun makes some trajectories to collide with the Earth. The\ud
corresponding quantity floats between 1 and 5 percent. As further exploration, we assume an\ud
uniform density of impact on the lunar surface, looking for the regions in the Earth–MoonPeer ReviewedPostprint (published version
THE SCUBA-2 COSMOLOGY LEGACY SURVEY: ALMA RESOLVES THE BRIGHT-END OF THE SUB-MILLIMETER NUMBER COUNTS

We present high-resolution 870 μm Atacama Large Millimeter/sub-millimeter Array (ALMA) continuum maps of 30 bright sub-millimeter sources in the UKIDSS UDS field. These sources are selected from deep, 1 degree2 850 μm maps from the SCUBA-2 Cosmology Legacy Survey, and are representative of the brightest sources in the field (median ${S}_{\mathrm{SCUBA}-2}$ = 8.7 ± 0.4 mJy). We detect 52 sub-millimeter galaxies (SMGs) at >4σ significance in our 30 ALMA maps. In ${61}_{-15}^{+19}\%$ of the ALMA maps the single-dish source comprises a blend of ≥2 SMGs, where the secondary SMGs are Ultra-luminous Infrared Galaxies (ULIRGs) with ${L}_{\mathrm{IR}}$ $\gtrsim $ 1012 ${\text{}}{L}_{\odot }$. The brightest SMG contributes on average ${80}_{-2}^{+6}\%$ of the single-dish flux density, and in the ALMA maps containing ≥2 SMGs the secondary SMG contributes ${25}_{-5}^{+1}\%$ of the integrated ALMA flux. We construct source counts and show that multiplicity boosts the apparent single-dish cumulative counts by 20% at S870 > 7.5 mJy, and by 60% at S870 > 12 mJy. We combine our sample with previous ALMA studies of fainter SMGs and show that the counts are well-described by a double power law with a break at 8.5 ± 0.6 mJy. The break corresponds to a luminosity of ~6 × 1012 ${\text{}}{L}_{\odot }$ or a star formation rate (SFR) of ~103 ${\text{}}{M}_{\odot }\;{\mathrm{yr}}^{-1}$. For the typical sizes of these SMGs, which are resolved in our ALMA data with ${R}_{{\rm{e}}}$ = 1.2 ± 0.1 kpc, this yields a limiting SFR density of ~100 ${\text{}}{M}_{\odot }$ yr−1 kpc−2 Finally, the number density of S870 $\gtrsim $ 2 mJy SMGs is 80 ± 30 times higher than that derived from blank-field counts. An over-abundance of faint SMGs is inconsistent with line-of-sight projections dominating multiplicity in the brightest SMGs, and indicates that a significant proportion of these high-redshift ULIRGs are likely to be physically associated.Peer-reviewedPublisher Versio
Analytic Representations of Yang-Mills Amplitudes

Scattering amplitudes in Yang-Mills theory can be represented in the
formalism of Cachazo, He and Yuan (CHY) as integrals over an auxiliary
projective space---fully localized on the support of the scattering equations.
Because solving the scattering equations is difficult and summing over the
solutions algebraically complex, a method of directly integrating the terms
that appear in this representation has long been sought. We solve this
important open problem by first rewriting the terms in a manifestly
Mobius-invariant form and then using monodromy relations (inspired by analogy
to string theory) to decompose terms into those for which combinatorial rules
of integration are known. The result is a systematic procedure to obtain
analytic, covariant forms of Yang-Mills tree-amplitudes for any number of
external legs and in any number of dimensions. As examples, we provide compact
analytic expressions for amplitudes involving up to six gluons of arbitrary
helicities.Comment: 29 pages, 43 figures; also included is a Mathematica notebook with
  explicit formulae. v2: citations added, and several (important) typos fixe
Restenosis, reocclusion and adverse cardiovascular events after successful balloon angioplasty of occluded versus nonoccluded coronary arteries: Results from the multicenter american research trial with cilazapril after angioplasty to prevent transluminal coronary obstruction and restenosis (MARCATOR)

OBJECTIVES: This study sought to compare the frequency of restenosis, reocclusion and adverse cardiovascular events after angioplasty of occluded versus nonoccluded coronary arteries.  \ud
BACKGROUND: Angioplasty of chronically occluded coronary arteries is believed to be associated with a higher frequency of restenosis and reocclusion than angioplasty of subtotal stenoses. Whether this leads to adverse cardiovascular events is unknown.  \ud
METHODS: The Multicenter American Research Trial With Cilazapril After Angioplasty to Prevent Restenosis (MARCATOR) was a placebo-controlled trial with angiographic follow-up to determine the effect of the angiotensin-converting enzyme inhibitor cilazapril on the frequency of restenosis. In this trial, restenosis was defined as 1) angiographic reduction of minimal lumen diameter > or = 0.72 mm between angioplasty and the follow-up visit; and 2) > 50% diameter stenosis on the follow-up angiogram. We identified 139 patients with successful angioplasty of a coronary occlusion (Group 1) and compared the frequency of restenosis, reocclusion and adverse cardiovascular events with that in 1,295 patients with successful angioplasty of a subtotal stenosis (Group 2).  \ud
RESULTS: Restenosis occurred in 36 patients with occluded arteries (29%) versus 264 with nonoccluded arteries (23%, p = 0.177) by definition 1 and in 62 patients with occluded arteries (49%) versus 478 with nonoccluded arteries (42%, p = 0.119) by definition 2. Occlusion was present in 24 Group 1 patients (19%) compared with 74 Group 2 patients (7%) (p < 0.001). During the 6 month follow-up period, two Group 1 patients (1.4%) and six Group 2 patients (0.5%) died; no Group 1 patients and 10 Group 2 patients (0.8%) developed severe congestive heart failure; nonfatal myocardial infarction occurred in 4 Group 1 patients (2.9%) and 31 Group 2 patients (2.4%); repeat coronary angioplasty or bypass surgery was performed in 29 Group 1 patients (21%) and 232 Group 2 patients (18%); and angina was present in 18 Group 1 and 163 Group 2 patients (13% for both). Eighty-six Group 1 patients (62%) and 853 Group 2 patients (66%) remained free of these adverse events during the 6-month follow-up period (p = 0.513).  \ud
CONCLUSIONS: The frequency of restenosis was slightly but not significantly greater after successful angioplasty of an occluded artery than after angioplasty of a subtotal stenosis. Although reocclusion was more frequent, occurring in 19% of patients, the net clinical benefit of angioplasty in such patients was similar to that in patients with subtotal stenoses over the 6-month follow-up period
Dark energy, the cosmic coincidence, and entanglement

We show that an inflation with the number of e-folds $N\simeq 65$ solves the cosmic coincidence problem in a natural manner in the context of holographic dark energy. Assuming the inflation and a power-law acceleration phase we obtain an analytical formula for the size of an event horizon of the universe as a function of time. A numerical study exploiting the formula qualitatively reproduces the observed evolution of the universe from the inflation to the present without fine tuning or ad hoc assumptions. This nontrivial coincidence between the theory and the observational data enhances the validity of holographic dark energy models including the entanglement dark energy model recently proposed
GammaLib and ctools
 : 
A software framework for the analysis of astronomical gamma-ray data

International audienceThe field of gamma-ray astronomy has seen important progress during the last decade, yet to date no common software framework has been developed for the scientific analysis of gamma-ray telescope data. We propose to fill this gap by means of the GammaLib software, a generic library that we have developed to support the analysis of gamma-ray event data. GammaLib was written in C++ and all functionality is available in Python through an extension module. Based on this framework we have developed the ctools software package, a suite of software tools that enables flexible workflows to be built for the analysis of Imaging Air Cherenkov Telescope event data. The ctools are inspired by science analysis software available for existing high-energy astronomy instruments, and they follow the modular ftools model developed by the High Energy Astrophysics Science Archive Research Center. The ctools were written in Python and C++, and can be either used from the command line via shell scripts or directly from Python. In this paper we present the GammaLib and ctools software versions 1.0 that were released at the end of 2015. GammaLib and ctools are ready for the science analysis of Imaging Air Cherenkov Telescope event data, and also support the analysis of Fermi-LAT data and the exploitation of the COMPTEL legacy data archive. We propose using ctools as the science tools software for the Cherenkov Telescope Array Observatory