pinecone/core-2020-05-10-deduplication huggingface dataset:
Outcomes Associated With Microalbuminuria: Effect Modificatin By Chronic Kidney Disease.

OBJECTIVES: To compare association of microalbuminuria with outcomes in patients with different comorbidities. BACKGROUND: The risk of adverse outcomes associated with proteinuria has been found to be linearly decreasing with even low-normal levels of microalbuminuria. It is unclear if comorbid conditions change these associations. METHODS: We examined the association of urine microalbumin-creatinine ratio (UACR) with mortality and the slopes of estimated glomerular filtration rate (eGFR) in a nationally representative cohort of 298,875 US veterans. Associations of UACR with all-cause mortality overall and in subgroups of patients with and without diabetes, hypertension, cardiovascular disease, congestive heart failure and advanced CKD were examined in Cox models, and with the slopes of eGFR in linear and logistic regression models. RESULTS: Very low levels of UACR were linearly associated with decreased mortality and less progression of CKD overall: adjusted mortality hazard ratio and estimated glomerular filtration rate slope (95%CI) associated with UACR =200, compared to <5 mcg/mg were 1.53 (1.38-1.69, p<0.001) and -1.59 (-1.83, -1.35, p<0.001). Similar linearity was present in all examined subgroups, except in patients with CKD in whom a U-shaped association was present and in whom a UACR of 10-19 was associated with the best outcomes. CONCLUSIONS: The association of UACR with mortality and with progressive CKD is modified in patients with CKD, who experience higher mortality and worse progression of CKD with the lowest levels of UACR. Proteinuria-lowering interventions in patients with advanced CKD should be implemented cautiously, considering the potential for adverse outcomes
Competition in the political arena and local government performance

This is the authors’ accepted and refereed manuscript to the article.
Publisher's webpage: www.tandfonline.com 
Availability of author's version is delayed until 18 months after first online publication. Unavailable until 2015-11-01. Publisher's policy.Competition reduces rent extraction in private-sector firms. In this article, we empirically assess whether it similarly disciplines politicians by evaluating local-level governments’ performance in Flanders. The results indicate that electoral competition – measured via the number of parties competing in elections – significantly positively affects the productive efficiency of municipal policy. Intertemporal competition – measured as the volatility of election outcomes over time – has a similar, but weaker, positive effect. These beneficial effects are mitigated by the fact that competition may lead to more fragmented governments, which is shown to work against their productive efficiency. Overall, though, the beneficial effects outweigh the unfavourable ones in our sample.1, Forfatterversjo
Hepatitis C virus infection protein network.

International audienceA proteome-wide mapping of interactions between hepatitis C virus (HCV) and human proteins was performed to provide a comprehensive view of the cellular infection. A total of 314 protein-protein interactions between HCV and human proteins was identified by yeast two-hybrid and 170 by literature mining. Integration of this data set into a reconstructed human interactome showed that cellular proteins interacting with HCV are enriched in highly central and interconnected proteins. A global analysis on the basis of functional annotation highlighted the enrichment of cellular pathways targeted by HCV. A network of proteins associated with frequent clinical disorders of chronically infected patients was constructed by connecting the insulin, Jak/STAT and TGFbeta pathways with cellular proteins targeted by HCV. CORE protein appeared as a major perturbator of this network. Focal adhesion was identified as a new function affected by HCV, mainly by NS3 and NS5A proteins
Admissible submonoids of Artin-Tits monoids

International audienceWe show the analogue of Muhlherr's [Coxeter groups in Coxeter groups, Finite Geom. and Combinatorics, Cambridge Univ. Press (1993), 277-287] for Artin-Tits monoids, and for Artin-Tits groups of spherical type. That is, the submonoid (resp. subgroup) of an Artin-Tits monoid (resp. group of spherical type) induced by an admissible partition of the Coxeter graph is an Artin-Tits monoid (resp. group). This generalizes and unifies the situation of the submonoid (resp. subgroup) of fixed elements of an Artin-Tits monoid (resp. group of spherical type) under the action of graph automorphisms, and the notion of LCM-homomorphisms defined by Crisp in [Injective maps between Artin groups, Geom. Group Theory Down Under, Canberra (1996) 119-137] and generalized by Godelle in [Morphismes injectifs entre groupes d'Artin-Tits, Algebr. Geom. Topol. 2 (2002), 519--536]. We then complete the classification of the admissible partitions for which the Coxeter graphs involved have no infinite label, started by Muhlherr in [Some contributions to the theory of buildings based on the gate property, Dissertation, Tübingen (1994)]. This leads us to the classification of Crisp's LCM-homomorphisms
Phoretic self-propulsion at finite Peclet numbers

International audiencePhoretic self-propulsion is a unique example of force- and torque-free motion on small scales. The classical framework describing the flow field around a particle swimming by self-diffusiophoresis neglects the advection of the solute field by the flow and assumes that the chemical interaction layer is thin compared to the particle size. In this paper we quantify and characterize the effect of solute advection on the phoretic swimming of a sphere. We first rigorously derive the regime of validity of the thin-interaction-layer assumption at finite values of the Péclet number (Pe). Under this assumption, we solve computationally the flow around Janus phoretic particles and examine the impact of solute advection on propulsion and the flow created by the particle. We demonstrate that although advection always leads to a decrease of the swimming speed and flow stresslet at high values of the Péclet number, an increase can be obtained at intermediate values of Pe. This possible enhancement of swimming depends critically on the nature of the chemical interactions between the solute and the surface. We then derive an asymptotic analysis of the problem at small Pe which allows us to rationalize our computational results. Our computational and theoretical analysis is accompanied by a parallel study of the influence of reactive effects at the surface of the particle (Damköhler number) on swimming
Pseudorapidity and transverse-momentum distributions of charged particles in proton–proton collisions at √s=13TeV

The pseudorapidity (η) and transverse-momentum (pT) distributions of charged particles produced in proton–proton collisions are measured at the centre-of-mass energy √s=13TeV. The pseudorapidity distribution in |η|<1.8is reported for inelastic events and for events with at least one charged particle in |η|<1. The pseudorapidity density of charged particles produced in the pseudorapidity region |η|<0.5is 5.31 ±0.18 and 6.46 ±0.19for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 <pT<20GeV/cand |η|<0.8for events with at least one charged particle in |η|<1. The evolution of the transverse momentum spectra of charged particles is also investigated as a function of event multiplicity. The results are compared with calculations from PYTHIA and EPOS Monte Carlo generators
Search for heavy Majorana neutrinos with the ATLAS detector in pp collisions at √s = 8TeV

Journal of High Energy Physics 2015.7 (2015): 162 reproduced by permission of Scuola Internazionale Superiore di Studi Avanzati (SISSA)A search for heavy Majorana neutrinos in events containing a pair of high-pT leptons of the same charge and high-pT jets is presented. The search uses 20.3 fb−1 of pp collision data collected with the ATLAS detector at the CERN Large Hadron Collider with a centre-of-mass energy of √s = 8 TeV. The data are found to be consistent with the background-only hypothesis based on the Standard Model expectation. In the context of a Type-I seesaw mechanism, limits are set on the production cross-section times branching ratio for production of heavy Majorana neutrinos in the mass range between 100 and 500 GeV. The limits are subsequently interpreted as limits on the mixing between the heavy Majorana neutrinos and the Standard Model neutrinos. In the context of a left-right symmetric model, limits on the production cross-section times branching ratio are set with respect to the masses of heavy Majorana neutrinos and heavy gauge bosons WR and Z′We thank CERN for the very successful operation of the LHC, as well as the support staff
from our institutions without whom ATLAS could not be operated efficiently.
We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia;
BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; RGC, Hong Kong SAR, China; ISF, MINERVA, GIF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW and NCN, Poland; GRICES and FCT, Portugal; MNE/IFA, Romania; MES of Russia and NRC KI, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MIZS, Slovenia; DST/NRF, South Africa; MINECO, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America.
The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN and the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF
(Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF
(Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (U.K.) and BNL (U.S.A.) and in the Tier-2 facilities worldwid
Search for extra dimensions using diphoton events in 7 TeV proton-proton collisions with the ATLAS detector

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMUsing data recorded in 2011 with the ATLAS detector at the Large Hadron Collider, a search for evidence of extra spatial dimensions has been performed through an analysis of the diphoton final state. The analysis uses data corresponding to an integrated luminosity of 2.12 fb−1 of √ s = 7 TeV proton– proton collisions. The diphoton invariant mass (mγγ ) spectrum is observed to be in good agreement with the expected Standard Model background. In the large extra dimension scenario of Arkani-Hamed, Dimopoulos and Dvali, the results provide 95% CL lower limits on the fundamental Planck scale between 2.27 and 3.53 TeV, depending on the number of extra dimensions and the theoretical formalism used. The results also set 95% CL lower limits on the lightest Randall–Sundrum graviton mass of between 0.79 and 1.85 TeV, for values of the dimensionless coupling k/MPl varying from 0.01 to 0.1. Combining with previously published ATLAS results from the dielectron and dimuon final states, the 95% CL lower limit on the Randall–Sundrum graviton mass for k/MPl = 0.01 (0.1) is 0.80 (1.95) TeVWe thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; ARTEMIS, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNAS, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN and the ATLAS Tier- 1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NLT1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA) and in the Tier-2 facilities worldwid
Grasping the past : delay can improve visuomotor performance.

“Optic ataxia” is caused by damage to the human posterior parietal cortex (PPC). It disrupts all components of a visually guided prehension movement, not only the transport of the hand toward an object's location [1], but also the in-flight finger movements pretailored to the metric properties of the object [2, 3 and 4]. Like previous cases [4 and 5], our patient (I.G.) was quite unable to open her handgrip appropriately when directly reaching out to pick up objects of different sizes. When first tested, she failed to do this even when she had previewed the target object 5 s earlier. Yet despite this deficit in “real” grasping, we found, counterintuitively, that I.G. showed good grip scaling when “pantomiming” a grasp for an object seen earlier but no longer present. We then found that, after practice, I.G. became able to scale her handgrip when grasping a real target object that she had previewed earlier. By interposing catch trials in which a different object was covertly substituted for the original object during the delay between preview and grasp, we found that I.G. was now using memorized visual information to calibrate her real grasping movements. These results provide new evidence that “off-line” visuomotor guidance can be provided by networks independent of the PPC
Dawes Review. The tidal downsizing hypothesis of planet formation

Tidal Downsizing is the modern version of the Kuiper (1951) scenario of
planet formation. Detailed simulations of self-gravitating discs, gas
fragments, dust grain dynamics, and planet evolutionary calculations are
summarised here and used to build a predictive planet formation model and
population synthesis. A new interpretation of exoplanetary and debris disc
data, the Solar System's origins, and the links between planets and brown
dwarfs is offered. This interpretation is contrasted with the current
observations and the predictions of the Core Accretion theory. Observations
that can distinguish the two scenarios are pointed out. In particular, Tidal
Downsizing predicts that presence of debris discs, sub-Neptune mass planets,
planets more massive than $\sim 5$~Jupiter masses and brown dwarfs should not
correlate strongly with the metallicity of the host. For gas giants of $\sim$
Saturn to a few Jupiter mass, a strong host star metallicity correlation is
predicted only inwards of a few AU from the host. Composition of massive cores
is predicted to be dominated by rock rather than ices. Debris discs made by
Tidal Downsizing are distinct from those made by Core Accretion at birth: they
have an innermost edge always larger than about 1 au, have smaller total masses
and are usually in a dynamically excited state. It is argued that planet
formation in surprisingly young or very dynamic systems such as HL Tau and
Kepler-444 may be a signature of Tidal Downsizing. Open questions and potential
weaknesses of the hypothesis are pointed out.Comment: 49 pages. Accepted by PASA. This is the pre final submission version
  -- comments welcom
Multiwavelength observations of a VHE gamma-ray flare from PKS 1510-089
  in 2015

Context. PKS 1510-089 is one of only a few flat spectrum radio quasars
detected in the VHE (very-high-energy, > 100 GeV) gamma-ray band. Aims. We
study the broadband spectral and temporal properties of the PKS 1510-089
emission during a high gamma-ray state. Methods. We performed VHE gamma-ray
observations of PKS 1510-089 with the MAGIC telescopes during a long high
gamma-ray state in May 2015. In order to perform broadband modelling of the
source, we have also gathered contemporaneous multiwavelength data in radio,
IR, optical photometry and polarization, UV, X-ray and GeV gamma-ray ranges. We
construct a broadband spectral energy distribution (SED) in two periods,
selected according to VHE gamma-ray state. Results. PKS 1510-089 has been
detected by MAGIC during a few day-long observations performed in the middle of
a long, high optical and gamma-ray state, showing for the first time a
significant VHE gamma-ray variability. Similarly to the optical and gamma-ray
high state of the source detected in 2012, it was accompanied by a rotation of
the optical polarization angle and the emission of a new jet component observed
in radio. However, due to large uncertainty on the knot separation time, the
association with the VHE gamma-ray emission cannot be firmly established. The
spectral shape in the VHE band during the flare is similar to the ones obtained
during previous measurements of the source. The observed flux variability sets
for the first time constraints on the size of the region from which VHE gamma
rays are emitted. We model the broadband SED in the framework of the external
Compton scenario and discuss the possible emission site in view of
multiwavelength data and alternative emission models.Comment: 12 pages, 10 figures, accepted for a publication in A&
The effect of oil sands process-affected water and model naphthenic acids on photosynthesis and growth in Emiliania huxleyi and Chlorella vulgaris.

Naphthenic acids (NAs) are among the most toxic organic pollutants present in oil sands process waters (OSPW) and enter marine and freshwater environments through natural and anthropogenic sources. We investigated the effects of the acid extractable organic (AEO) fraction of OSPW and individual surrogate NAs, on maximum photosynthetic efficiency of photosystem II (PSII) (FV/FM) and cell growth in Emiliania huxleyi and Chlorella vulgaris as representative marine and freshwater phytoplankton. Whilst FV/FM in E. huxleyi and C. vulgaris was not inhibited by AEO, exposure to two surrogate NAs: (4'-n-butylphenyl)-4-butanoic acid (n-BPBA) and (4'-tert-butylphenyl)-4-butanoic acid (tert-BPBA), caused complete inhibition of FV/FM in E. huxleyi (≥10 mg L(-1)n-BPBA; ≥50 mg L(-1)tert-BPBA) but not in C. vulgaris. Growth rates and cell abundances in E. huxleyi were also reduced when exposed to ≥10 mg L(-1)n- and tert-BPBA; however, higher concentrations of n- and tert-BPBA (100 mg L(-1)) were required to reduce cell growth in C. vulgaris. AEO at ≥10 mg L(-1) stimulated E. huxleyi growth rate (p ≤ 0.002), yet had no apparent effect on C. vulgaris. In conclusion, E. huxleyi was generally more sensitive to NAs than C. vulgaris. This report provides a better understanding of the physiological responses of phytoplankton to NAs which will enable improved monitoring of NA pollution in aquatic ecosystems in the future
Anomalies of the entanglement entropy in chiral theories.

We study entanglement entropy in theories with gravitational or mixed U(1) gauge-gravitational anomalies in two, four and six dimensions. In such theories there is an anomaly in the entanglement entropy: it depends on the choice of reference frame in which the theory is regulated. We discuss subtleties regarding regulators and entanglement entropies in anomalous theories. We then study the entanglement entropy of free chiral fermions and self-dual bosons and show that in sufficiently symmetric situations this entanglement anomaly comes from an imbalance in the flux of modes flowing through the boundary, controlled by familiar index theorems.\ud
\ud
In two and four dimensions we use anomalous Ward identities to find general expressions for the transformation of the entanglement entropy under a diffeomorphism. (In the case of a mixed anomaly there is an alternative presentation of the theory in which the entanglement entropy is not invariant under a U(1) gauge transformation. The free-field manifestation of this phenomenon involves a novel kind of fermion zero mode on a gravitational background with a twist in the normal bundle to the entangling surface.) We also study d-dimensional anomalous systems as the boundaries of d+1 dimensional gapped Hall phases. Here the full system is non-anomalous, but the boundary anomaly manifests itself in a change in the entanglement entropy when the boundary metric is sheared relative to the bulk
Search for physics beyond the standard model in events with two leptons, jets, and missing transverse momentum in pp collisions at √s = 8 TeV

A search is presented for physics beyond the standard model in final states with two opposite-sign same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 19.4 fb[superscript −1] of proton-proton collisions at √s = 8 TeV collected with the CMS detector at the CERN LHC in 2012. The analysis focuses on searches for a kinematic edge in the invariant mass distribution of the oppositesign same-flavor lepton pair and for final states with an on-shell Z boson. The observations are consistent with expectations from standard model processes and are interpreted in terms of upper limits on the production of supersymmetric particles.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
Measurement of the $Zγ → ν\overline{ν}γ$ production cross section in pp collisions at $\sqrt{s}$ = 8 TeV and limits on anomalous ZZγ and Zγγ trilinear gauge boson couplings

An inclusive measurement of the $Zγ → ν\overline{ν}γ$ production cross section in pp collisions at $\sqrt{s}$=8TeV is presented, using data corresponding to an integrated luminosity of 19.6 fb$^{−1}$ collected with the CMS detector at the LHC. This measurement is based on the observation of events with large missing energy and with a single photon with transverse momentum above 145 GeV and absolute pseudorapidity in the range |η|<1.44 . The measured Zγ→νν‾γ production cross section, 52.7±2.1 (stat)±6.4 (syst)±1.4 (lumi) fb , agrees well with the standard model prediction of 50.0−2.2+2.4 fb . A study of the photon transverse momentum spectrum yields the most stringent limits to date on the anomalous ZZγ and Zγγ trilinear gauge boson couplings