pinecone/core-2020-05-10-deduplication huggingface dataset:
Spatial variation of the cooling lines in the reflection   nebula NGC 7023

International audienceContext. The north-west photo-dissociation region (PDR) in the reflection nebula NGC 7023 displays a complex structure. Filament-like condensations at the edge of the cloud can be traced via the emission of the main cooling lines, offering a great opportunity to study the link between the morphology and energetics of these regions.Aims. We study the spatial variation of the far-infrared fine-structure lines of [C ii] (158 μm) and [O i] (63 and 145 μm). These lines trace the local gas conditions across the PDR. We also compare their emission with molecular tracers including rotational and ro-vibrational lines of H2 and high-rotational lines of CO.Methods. We used observations from the Herschel/PACS instrument to map the spatial distribution of these fine-structure lines. The observed region covers a square area of about 110″ × 110″ with an angular resolution that varies from 4′′ to 11′′. We compared this emission with ground-based and Spitzer observations of H2 lines, Herschel/SPIRE observations of CO lines, and Spitzer/IRAC 3.6 μm images that trace the emission of polycyclic aromatic hydrocarbons. We used a PDR code to model the [O i]145 μm line and infer the physical conditions in the region.Results. The [C ii] (158 μm) and [O i] (63 and 145 μm) lines arise from the warm cloud surface where the PDR is located and the gas is warm, cooling the region. We find that although the relative contribution to the cooling budget over the observed region is dominated by [O i]63 μm (>30%), H2 contributes significantly in the PDR (~35%), as does [C ii]158 μm outside the PDR (30%). Other species contribute little to the cooling ([O i]145 μm 9%, and CO 4%). Enhanced emission of these far-infrared atomic lines trace the presence of condensations, where high-excitation CO rotational lines and dust emission in the submillimetre are detected as well. The [O i] maps resolve these condensations into two structures and show that the peak of [O i] is slightly displaced from the molecular H2 emission. The size of these structures is about 8″ (0.015 pc) and in surface cover about 9% of the PDR emission. We have tested whether the density profile and peak densities that were derived in previous studies to model the dust and molecular emission can predict the [O i]145 μm emission. We find that the model with a peak density of 106 cm-3, and 2 × 104−5 cm-3 in the oxygen emitting region predicts an [O i]145 μm line that is only 30% lower than the observed emission. Finally, we did not detect emission from [N ii]122 μm, suggesting that the cavity is mostly filled with non-ionised gas
Green nanochemistry: Metal oxide nanoparticles and porous thin films from bare metal powders

A universal, simple, robust, widely applicable and cost-effective aqueous process is described for a controlled oxidative dissolution process of micrometer-sized metal powders to form high-purity aqueous dispersions of colloidally stable 3-8 nm metal oxide nanoparticles. Their utilization for making single and multilayer optically transparent high-surface-area nanoporous films is demonstrated. This facile synthesis is anticipated to find numerous applications in materials science, engineering, and nanomedicine. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Theory of Solvation Controlled Reactions in Stimuli Responsive Nanoreactors

Metallic nanoparticles embedded in stimuli responsive polymers can be regarded as nanoreactors because their catalytic activity can be changed within wide limits  the physicochemical properties of the polymer network can be tuned and switched by external parameters, for example, temperature or pH, and thus allow a selective control of reactant mobility and concentration close to the reaction site. Combining Debye s model of diffusion through an  energy landscape and a two state model for the polymer, here we develop an analytical expression for the observed reaction rate constant, kobs. Our formula shows an exponential dependence of this rate on the solvation free enthalpy change  amp; 916;G amp; 773;sol, a quantity that describes the partitioning of the reactant in the network versus bulk. Thus, changes in  amp; 916;G amp; 773;sol, and not in the diffusion coefficient, will be the decisive factor affecting the reaction rate in most cases. A comparison with recent experimental data on switchable, thermosensitive nanoreactors demonstrates the general validity of the concep
ATLAS search for new phenomena in dijet mass and angular distributions using pp collisions at s√=7 TeV

Mass and angular distributions of dijets produced in LHC proton-proton collisions at a centre-of-mass energy s√=7TeV have been studied with the ATLAS detector using the full 2011 data set with an integrated luminosity of 4.8 fb−1. Dijet masses up to ~ 4.0 TeV have been probed. No resonance-like features have been observed in the dijet mass spectrum, and all angular distributions are consistent with the predictions of QCD. Exclusion limits on six hypotheses of new phenomena have been set at 95% CL in terms of mass or energy scale, as appropriate. These hypotheses include excited quarks below 2.83 TeV, colour octet scalars below 1.86 TeV, heavy W bosons below 1.68 TeV, string resonances below 3.61 TeV, quantum black holes with six extra space-time dimensions for quantum gravity scales below 4.11 TeV, and quark contact interactions below a compositeness scale of 7.6 TeV in a destructive interference scenario.We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America
Search for heavy, top-like quark pair production in the dilepton final state in pp collisions at √s = 7 TeV

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMThe results of a search for pair production of a heavy, top-like quark, tꞌ, in the decay mode tꞌ tꞌ → bW + bW− →bℓ+ νbℓ −ν are presented. The search is performed with a data sample corresponding to an integrated luminosity of 5.0 fb−1 in pp collisions at a center-of-mass energy of 7 TeV, collected by the CMS experiment at the LHC. The observed number of events agrees with the expectation from standard model processes, and no evidence of tꞌ tꞌ production is found. Upper limits on the production cross section as a function of tꞌ mass are presented, and tꞌ masses below 557 GeV/c2 are excluded at the 95% confidence levelWe congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC machine. We thank the technical and administrative staff at CERN and other CMS institutes, and acknowledge support from: FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); MSI (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MON, RosAtom, RAS and RFBR (Russia); MSTD (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA
Deep inelastic lepton scattering in nuclei at x>1 and the nucleon spectral function

The nuclear structure function F_2A(x) has been studied in the Bjorken limit for (l, l') scattering on nuclei in the region of x > 1 and was found to be very sensitive to the information contained in the nucleon spectral function in nuclei, particularly the correlations between momenta and energies in the region of large momenta. Calculations were done in a local density approximation using two different spectral functions for nuclear matter. Results are compared to those obtained for a spectral function which has been evaluated directly for the finite nucleus, ^{16}O, under consideration. For values of x around 1.5 and larger the quasiparticle contribution is negligible, thus stressing the sensitivity of the present reaction to the dynamical properties of nuclei beyond the shell model approach. Several approximations which are usually employed in studies of the EMC effect have been analyzed and their inaccuracy in this region is demonstrated. The results stress the fact that the nuclear structure function contains important information on nuclear dynamical correlations. Therefore further measurements of F_2A(x) in that region and for many nuclei would be most welcome
Neonatal exposure to 17 beta-estradiol down-regulates the expression of synaptogenesis related genes in selected brain regions of adult female rats

Aims: Administration of estradiol or compounds with estrogenic activity to newborn female rats results in irreversible masculinization as well as defeminization in the brain and the animals exhibit altered reproductive behavior as adults. The cellular and molecular mechanism involved in inducing the irreversible changes is largely unknown. In the present study, we have monitored the changes in the expression of selected synaptogenesis related genes in the sexually dimorphic brain regions such as POA, hypothalamus and pituitary following 17 beta-estradiol administration to neonatal female rats. \ud
\ud
Main methods: Female Wistar rats which were administered 17 beta-estradiol on day 2 and 3 after birth were sacrificed 120 days later and the expression levels of genes implicated in synaptogenesis were monitored by semi-quantitative reverse transcription PCR. Since estradiol induced up-regulation of COX-2 in POA is a marker for estradiol induced masculinization as well as defeminization, in the present study only animals in which the increase in expression of COX-2 gene was observed in POA were included in the study. \ud
Key findings: Down-regulation of genes such as NMDA-2B, NETRIN-1, BDNF, MT-5 MMP and TNF-alpha was observed in the pre-optic area of neonatally E2 treated female rat brain but not in hypothalamus and pituitary compared to the vehicle- treated controls as assessed by RT-PCR and Western blot analysis. \ud
Significance: Our results suggest a possibility that down-regulation of genes associated with synaptogenesis in POA, may be resulting in disruption of the cyclical regulation of hormone secretion by pituitary the consequence of which could be infertility and altered reproductive behavior. (C) 2015 Elsevier Inc. All rights reserved
Black Hole Thermodynamics with Conical Defects

Recently we have shown [1604.08812] how to formulate a thermodynamic first
law for a single (charged) accelerated black hole in AdS space by fixing the
conical deficit angles present in the spacetime. Here we show how to generalise
this result, formulating thermodynamics for black holes with varying conical
deficits. We derive a new potential for the varying tension defects: the
"thermodynamic length", both for accelerating and static black holes. We
discuss possible physical processes in which the tension of a string ending on
a black hole might vary, and also map out the thermodynamic phase space of
accelerating black holes and explore their critical phenomena.Comment: 26 pages, 8 figure
Insulin acutely improves mitochondrial function of rat and human skeletal muscle by increasing coupling efficiency of oxidative phosphorylation.

Insulin is essential for the regulation of fuel metabolism and triggers the uptake of glucose by skeletal muscle. The imported glucose is either stored or broken down, as insulin stimulates glycogenesis and ATP synthesis. The mechanism by which ATP production is increased is incompletely understood at present and, generally, relatively little functional information is available on the effect of insulin on mitochondrial function. In this paper we have exploited extracellular flux technology to investigate insulin effects on the bioenergetics of rat (L6) and human skeletal muscle myoblasts and myotubes. We demonstrate that a 20-min insulin exposure significantly increases (i) the cell respiratory control ratio, (ii) the coupling efficiency of oxidative phosphorylation, and (iii) the glucose sensitivity of anaerobic glycolysis. The improvement of mitochondrial function is explained by an insulin-induced immediate decrease of mitochondrial proton leak. Palmitate exposure annuls the beneficial mitochondrial effects of insulin. Our data improve the mechanistic understanding of insulin-stimulated ATP synthesis, and reveal a hitherto undisclosed insulin sensitivity of cellular bioenergetics that suggests a novel way of detecting insulin responsiveness of cells
The benefits of integration.

Retroviruses, including the human immunodeficiency virus (HIV), are notorious for two essential steps of their viral replication: reverse transcription and integration. This latter property is considered to be essential for productive replication and ensures the stable long-term insertion of the viral genome sequence in the host chromatin, thereby leading to the life-long association of the virus with the infected cell. Using HIV as a prototypic example, the present review aims to provide an overview of how and where integration occurs, as well as presenting general consequences for both the virus and the infected host
An affected core drives network integration deficits of the structural connectome in 22q11.2 deletion syndrome.

Chromosome 22q11.2 deletion syndrome (22q11DS) is a genetic disease known to lead to cerebral structural alterations, which we study using the framework of the macroscopic white-matter connectome. We create weighted connectomes of 44 patients with 22q11DS and 44 healthy controls using diffusion tensor magnetic resonance imaging, and perform a weighted graph theoretical analysis. After confirming global network integration deficits in 22q11DS (previously identified using binary connectomes), we identify the spatial distribution of regions responsible for global deficits. Next, we further characterize the dysconnectivity of the deficient regions in terms of sub-network properties, and investigate their relevance with respect to clinical profiles. We define the subset of regions with decreased nodal integration (evaluated using the closeness centrality measure) as the affected core (A-core) of the 22q11DS structural connectome. A-core regions are broadly bilaterally symmetric and consist of numerous network hubs - chiefly parietal and frontal cortical, as well as subcortical regions. Using a simulated lesion approach, we demonstrate that these core regions and their connections are particularly important to efficient network communication. Moreover, these regions are generally densely connected, but less so in 22q11DS. These specific disturbances are associated to a rerouting of shortest network paths that circumvent the A-core in 22q11DS, "de-centralizing" the network. Finally, the efficiency and mean connectivity strength of an orbito-frontal/cingulate circuit, included in the affected regions, correlate negatively with the extent of negative symptoms in 22q11DS patients, revealing the clinical relevance of present findings. The identified A-core overlaps numerous regions previously identified as affected in 22q11DS as well as in schizophrenia, which approximately 30-40% of 22q11DS patients develop
Supermarket choice, shopping behavior, socioeconomic status and food purchases

INTRODUCTION:
Both socioeconomic status and supermarket choice have been associated with diet
quality. This study aimed to assess the contributions of: (1) supermarket choice and (2) shopping behaviors to (a) the healthfulness of purchases and (b) social patterning in
purchases.

METHODS:
Observational panel data on purchases of fruit and vegetables and less healthy foods/beverages from 2010 were obtained for 24,879 households, stratified by occupational social class (analyzed 2014). Households’ supermarket choice was determined by whether they ever visited market-defined high-price and/or low-price supermarkets. Analyses also explored extent of use within supermarket choice groups.
Shopping behaviors included trip frequency, trip size, and number of store chains visited.

RESULTS:
Households using low-price (and not high-price) supermarkets purchased significantly lower percentages of energy from fruit and vegetables and higher percentages of energy from less healthy foods/beverages than households using high-price (and not low-price) supermarkets.

When controlling for socioeconomic status and shopping behaviors, the effect of supermarket choice was largely maintained for fruit and vegetables, but reduced for less healthy foods/beverages. The extent of use of low- or high-price supermarkets had limited effects on outcomes. More frequent trips and fewer small trips were associated with healthier purchasing for both outcomes, while visiting more store chains was associated with higher percentages of energy from fruit and vegetables. 

CONCLUSIONS:
While both supermarket choice and shopping behaviors influence healthfulness of 
purchases, neither appeared to contribute to socioeconomic differences. Moreover, differences between supermarket environments may not be primary drivers of the influence of supermarket choice.The study was funded by the Department of Health Policy Research Programme (http://prp.dh.gov.uk/) (Policy Research Unit in Behaviour and Health [PR-UN-0409-10109]). The Department of Health had no role in the study design, data collection, analysis, interpretation, or decision to submit for publication. The research was conducted independently of the funders, and the views expressed in this paper are those of the authors and not necessarily those of the Department of Health in England.  Pablo Monsivais also received support from the Centre for Diet and Activity Research, a United Kingdom Clinical Research Collaboration Public Health Research Centre of Excellence funded by the British Heart Foundation, Economic and Social Research Council, Medical Research Council, the National Institute for Health Research, and the Wellcome Trust. None of these funders played any role in the study design, data collection, analysis, interpretation, or decision to submit for publication.This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.amepre.2015.04.02
Blind source separation aided characterization of the γ’ strengthening phase in an advanced nickel-based superalloy by spectroscopic 4D electron microscopy

The γ’ strengthening phase in an advanced nickel-based superalloy, ATI 718Plus, was characterized using a blind source separation applied to a four dimensional X-ray microanalysis dataset obtained by scanning transmission electron microscopy. Selected patterns in the X-ray spectra identified by independent component analysis were found to be spatially and chemically representative of the matrix (γ) and precipitate phases (γ’) present in the superalloy, enabling their size, shape and distribution to be determined. The three dimensional chemical reconstruction of the microstructure may provide insight into the role of the various alloying elements in the evolution of the microstructure at the nano-scale.The research leading to these results has received funding from the European Union Seventh Framework Programme under Grant Agreement 312483 - ESTEEM2 (Integrated Infrastructure Initiative-I3), as well as from the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013)/ERC grant agreement 291522 - 3DIMAGE. D.R. acknowledges support from the Royal Society’s Newton International Fellowship scheme. RKL acknowledges a Junior Research Fellowship at Clare College. RK acknowledges financial support from Rolls-Royce, EPSRC and the BMWi under EP/H022309/1, EP/H500375/1 and grant number 20T0813. F.d.l.P. and C.D. acknowledge  26 funding from the ERC under grant no. 259619 PHOTO EM. Special thanks to Giorgio Divitini and Lech Staniewicz for preparation of the FIB needle specimen and to Stephen A Croxall for SEM/FIB imaging.This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.actamat.2016.01.04
An entangled-LED-driven quantum relay over 1 km

Quantum cryptography allows confidential information to be communicated between two parties, with secrecy guaranteed by the laws of nature alone. However, upholding guaranteed secrecy over networks poses a further challenge, as classical receive-and-resend routing nodes can only be used conditional of trust by the communicating parties, which arguably diminishes the value of the underlying quantum cryptography. Quantum relays offer a potential solution by teleporting qubits from a sender to a receiver, without demanding additional trust from end users. Here we demonstrate the operation of a quantum relay over 1 km of optical fibre, which teleports a sequence of photonic quantum bits to a receiver by utilising entangled photons emitted by a semiconductor light-emitting diode. The average relay fidelity of the link is 0.90±0.03, exceeding the classical bound of 0.75 for the set of states used, and sufficiently high to allow error correction. The fundamentally low multiphoton emission statistics and the integration potential of the source present an appealing platform for future quantum networks.The authors would like to acknowledge partial financial support through the UK EPSRC and the EU Marie Curie Initial Training Network Spin-optronics.This is the final version of the article. It first appeared from Nature Publishing Group via http://dx.doi.org/10.1038/npjqi.2016.