pinecone/core-2020-05-10-deduplication huggingface dataset:
Formation spectra of charmed meson--nucleus systems using an antiproton
  beam

We investigate the structure and formation of charmed meson--nucleus systems,
with the aim of understanding the charmed meson--nucleon interactions and the
properties of the charmed mesons in the nuclear medium. The $\bar{D}$ mesic
nuclei are of special interest, since they have tiny decay widths due to the
absence of strong decays for the $\bar{D} N$ pair. Employing an effective model
for the $\bar{D} N$ and $D N$ interactions and solving the Klein--Gordon
equation for $\bar{D}$ and $D$ in finite nuclei, we find that the
$D^{-}$-${}^{11}\rm{B}$ system has $1 s$ and $2p$ mesic nuclear states and that
the $D^{0}$-${}^{11}\rm{B}$ system binds in a $1s$ state. In view of the
forthcoming experiments by the PANDA and CBM Collaborations at the future FAIR
facility and the J-PARC upgrade, we calculate the formation spectra of the
$[D^{-}$-${}^{11}\rm{B}]$ and $[D^{0}$-${}^{11}\rm{B}]$ mesic nuclei for an
antiproton beam on a ${}^{12} \rm{C}$ target. Our results suggest that it is
possible to observe the $2 p$ $D^{-}$ mesic nuclear state with an appropriate
experimental setup.Comment: 8 pages, 5 figure
Search for single production of a vector-like quark via a heavy gluon in
  the $4b$ final state with the ATLAS detector in $pp$ collisions at $\sqrt{s}
  = 8$ TeV

A search is performed for the process $pp \to G^* \to B_H\bar b/\bar B_H b
\to H b \bar b \to b\bar bb\bar b$, predicted in composite Higgs scenarios,
where $G^*$ is a heavy colour octet vector resonance and $B_H$ a vector-like
quark of charge $-1/3$. The data were obtained from $pp$ collisions at a
centre-of-mass energy of 8 TeV corresponding to an integrated luminosity of
19.5 fb$^{-1}$, recorded by the ATLAS detector at the LHC. The largest
background, multijet production, is estimated using a data-driven method. No
significant excess of events with respect to Standard Model predictions is
observed, and upper limits on the production cross section times branching
ratio are set. Comparisons to the predictions from a specific benchmark model
are made, resulting in lower mass limits in the two-dimensional mass plane of
$m_{G^*}$ vs. $m_{B_H}$.Comment: 36 pages, 5 figures, 5 tables. All figures including auxiliary
  figures are available at
  http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2014-1
Constraints on $s-\bar s$ asymmetry of the proton in chiral effective
  theory

We compute the $s-\bar s$ asymmetry in the proton in chiral effective theory,
using phenomenological constraints based upon existing data. Unlike previous
meson cloud model calculations, which accounted for kaon loop contributions
with on-shell intermediate states alone, this work includes off-shell terms and
contact interactions, which impact the shape of the $s-\bar s$ difference. We
identify a valence-like component of $s(x)$ which is balanced by a
$\delta$-function contribution to $\bar s(x)$ at $x=0$, so that the integrals
of $s$ and $\bar s$ over the experimentally accessible region $x > 0$ are not
equal. Using a regularization procedure that preserves chiral symmetry and
Lorentz invariance, we find that existing data limit the integrated value of
the second moment of the asymmetry to the range $-0.07 \times 10^{-3} \leq
\langle x(s-\bar s) \rangle \leq 1.12 \times 10^{-3}$ at a scale of $Q^2=1
$GeV$^2$. This is too small to account for the NuTeV anomaly and of the wrong
sign to enhance it.Comment: 5 pages, 4 figure
Search for new resonances decaying to a $W$ or $Z$ boson and a Higgs
  boson in the $\ell^+ \ell^- b\bar b$, $\ell \nu b\bar b$, and $\nu\bar{\nu}
  b\bar b$ channels with $pp$ collisions at $\sqrt s = 13$ TeV with the ATLAS
  detector

A search is presented for new resonances decaying to a $W$ or $Z$ boson and a
Higgs boson in the $\ell^+ \ell^- b\bar b$, $\ell\nu b\bar b$, and
$\nu\bar{\nu} b\bar b$ channels in $pp$ collisions at $\sqrt s = 13$ TeV with
the ATLAS detector at the Large Hadron Collider using a total integrated
luminosity of 3.2 fb$^{-1}$. The search is conducted by looking for a localized
excess in the $WH$/$ZH$ invariant or transverse mass distribution. No
significant excess is observed, and the results are interpreted in terms of
constraints on a simplified model based on a phenomenological Lagrangian of
heavy vector triplets.Comment: 18 pages (plus author list + cover pages: 36 pages total), 13
  figures, 1 table. Submitted to PLB. All figures including auxiliary figures
  are available at
  https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2015-18
Reduced alfa-MSH underlies hypothalamic ER-stress-induced hepatic gluconeogenesis

Alterations in ER homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations. However, the neurobiological basis linking hypothalamic ER stress with abnormal glucose metabolism remains unknown. Here, we report that genetic and induced models of hypothalamic ER stress are associated with alterations in systemic glucose homeostasis due to increased gluconeogenesis (GNG) independent of body weight changes. Defective alpha melanocyte-stimulating hormone (α-MSH) production underlies this metabolic phenotype, as pharmacological strategies aimed at rescuing hypothalamic α-MSH content reversed this phenotype at metabolic and molecular level. Collectively, our results posit defective α-MSH processing as a fundamental mediator of enhanced GNG in the context of hypothalamic ER stress and establish α-MSH deficiency in proopiomelanocortin (POMC) neurons as a potential contributor to the pathophysiology of T2D
Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth.

Sildenafil, an inhibitor of the cGMP-degrading phosphodiesterase 5 that is used to treat erectile dysfunction, has been linked to an increased risk of melanoma. Here, we have examined the potential connection between cGMP-dependent signaling cascades and melanoma growth. Using a combination of biochemical assays and real-time monitoring of melanoma cells, we report a cGMP-dependent growth-promoting pathway in murine and human melanoma cells. We document that C-type natriuretic peptide (CNP), a ligand of the membrane-bound guanylate cyclase B, enhances the activity of cGMP-dependent protein kinase I (cGKI) in melanoma cells by increasing the intracellular levels of cGMP. Activation of this cGMP pathway promotes melanoma cell growth and migration in a p44/42 MAPK-dependent manner. Sildenafil treatment further increases intracellular cGMP concentrations, potentiating activation of this pathway. Collectively, our data identify this cGMP-cGKI pathway as the link between sildenafil usage and increased melanoma risk
Responding to global challenges in food, energy, environment and water: Risks and options assessment for decision-making

We analyse the threats of global environmental change, as they relate to food security. First, we review three discourses: (i) 'sustainable intensification', or the increase of food supplies without compromising food producing inputs, such as soils and water; (ii) the 'nexus' that seeks to understand links across food, energy, environment and water systems; and (iii) 'resilience thinking' that focuses on how to ensure the critical capacities of food, energy and water systems are maintained in the presence of uncertainties and threats. Second, we build on these discourses to present the causal, risks and options assessment for decision-making process to improve decision-making in the presence of risks. The process provides a structured, but flexible, approach that moves from problem diagnosis to better risk-based decision-making and outcomes by responding to causal risks within and across food, energy, environment and water systems. (Résumé d'auteur
Combined loss of Tet1 and Tet2 promotes B-cell, but not myeloid malignancies in mice.

TET1/2/3 are methylcytosine dioxygenases that regulate cytosine hydroxymethylation. Tet1/2 are abundantly expressed in HSC/HPCs and are implicated in hematological malignancies. Tet2-deletion in mice causes myeloid malignancies, while Tet1-null mice develop B-cell lymphoma after an extended period of latency. Interestingly, TET1/2 are often concomitantly downregulated in acute B-lymphocytic leukemia. Here, we investigated the overlapping and non-redundant functions of Tet1/2 in HSC maintenance and development of hematological malignancies using Tet1/2 double knockout (DKO) mice. DKO and Tet2−/− HSC/HPCs showed overlapping and unique 5hmC and 5mC profiles, and behaved differently. DKO mice exhibited strikingly decreased incidence and delayed-onset  of myeloid malignancies compared to Tet2−/− mice, and in contrast developed lethal B-cell malignancies. Transcriptome analysis of DKO tumors revealed expression changes in many genes dysregulated in human B-cell malignancies, such  as LMO2, BCL6 and MYC. These results highlight the critical roles of TET1/2 individually and together via communication in the pathogenesis of hematological  malignancies
Literature review and meta-analysis of translaminar pressure difference in openangle glaucoma

There is increasing evidence in the literature regarding translaminar pressure difference’s (TPD) role in the pathophysiology of glaucoma. The optic nerve is exposed not only to intraocular pressure in the eye, but also to intracranial pressure (ICP), as it is surrounded by cerebrospinal fluid in the subarachnoid space. Although pilot studies have identified the potential importance of TPD in glaucoma, limited available data currently prevent a comprehensive description of the role that TPD may have in glaucomatous pathophysiology. In this review, we present all available qualified data from a systematic review of the literature of the role of TPD in open-angle glaucoma (OAG). PubMed (Medline), OVID Medline, ScienceDirect, SpringerLink, and all available library databases were reviewed and subsequent meta-analysis of pooled mean differences are presented where appropriate. Five papers including 396 patients met criteria for inclusion to the analysis. Importantly, we included all observational studies despite differences in ICP measurement methods, as there is no consensus regarding best-practice ICP measurements in glaucoma. Our results show that not only TPD is higher in glaucoma patients compared with healthy subjects, it is related to structural glaucomatous changes of the optic disc. Our analysis suggests further longitudinal prospective studies are needed to investigate the influence of TPD in OAG, with a goal of overcoming methodological weaknesses of previous studies
Extensive, water-rich magma reservoir beneath southern Montserrat

South Soufrière Hills and Soufrière Hills volcanoes are 2 km apart at the southern end of the island of Montserrat, West Indies. Their magmas are distinct geochemically, despite these volcanoes having been active contemporaneously at 131–129 ka. We use the water content of pyroxenes and melt inclusion data to reconstruct the bulk water contents of magmas and their depth of storage prior to eruption. Pyroxenes contain up to 281 ppm H2O, with significant variability between crystals and from core to rim in individual crystals. The Al content of the enstatites from Soufrière Hills Volcano (SHV) is used to constrain melt-pyroxene partitioning for H2O. The SHV enstatite cores record melt water contents of 6–9 wt%. Pyroxene and melt inclusion water concentration pairs from South Soufriere Hills basalts independently constrain pyroxene-melt partitioning of water and produces a comparable range in melt water concentrations. Melt inclusions recorded in plagioclase and in pyroxene contain up to 6.3 wt% H2O. When combined with realistic melt CO2 contents, the depth of magma storage for both volcanoes ranges from 5 to 16 km. The data are consistent with a vertically protracted crystal mush in the upper crust beneath the southern part of Montserrat which contains heterogeneous bodies of eruptible magma. The high water contents of the magmas suggest that they contain a high proportion of exsolved fluids, which has implications for the rheology of the mush and timescales for mush reorganisation prior to eruption. A depletion in water in the outer 50–100 μm of a subset of pyroxenes from pumices from a Vulcanian explosion at Soufrière Hills in 2003 is consistent with diffusive loss of hydrogen during magma ascent over 5–13 h. These timescales are similar to the mean time periods between explosions in 1997 and in 2003, raising the possibility that the driving force for this repetitive explosive behaviour lies not in the shallow system, but in the deeper parts of a vertically protracted crustal magma storage system
A Language for Verification and Manipulation of Web Documents

International audienceIn this paper we develop the language theory underpinning the logical framework PLF. This language features lambda abstraction with patterns and application via pattern-matching. Reductions are allowed in patterns. The framework is particularly suited as a metalanguage for encoding rewriting logics and logical systems where proof terms have a special syntactic constraints, as in term rewriting systems, and rule-based languages. PLF is a conservative extension of the well-known Edinburgh Logical Framework LF. Because of sophisticated pattern matching facilities PLF is suitable for verification and manipulation of HXML documents
Searches for heavy long-lived sleptons and R-Hadrons with the ATLAS detector in pp collisions at s√=7 TeV

A search for long-lived particles is performed using a data sample of 4.7 fb−1 from proton–proton
collisions at a centre-of-mass energy √s = 7 TeV collected by the ATLAS detector at the LHC. No excess
is observed above the estimated background and lower limits, at 95% confidence level, are set on the
mass of the long-lived particles in different scenarios, based on their possible interactions in the inner
detector, the calorimeters and the muon spectrometer. Long-lived staus in gauge-mediated SUSY-breaking
models are excluded up to a mass of 300 GeV for tan β = 5–20. Directly produced long-lived sleptons are
excluded up to a mass of 278 GeV. R-hadrons, composites of gluino (stop, sbottom) and light quarks,
are excluded up to a mass of 985 GeV (683 GeV, 612 GeV) when using a generic interaction model.
Additionally two sets of limits on R-hadrons are obtained that are less sensitive to the interaction model
for R-hadrons. One set of limits is obtained using only the inner detector and calorimeter observables,
and a second set of limits is obtained based on the inner detector alone.We acknowledge the support of ANPCyT, Argentina; YerPhl, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America
The sensory quality of meat, game, poultry, seafood and meat products as affected by intense light pulses : a systematic review

The effect of intense light pulses (ILP) on sensory quality of 16 different varieties of meat, meat products, game, poultry and seafood are reviewed. Changes induced by ILP are animal species, type of meat product and fluences applied dependent. ILP significantly deteriorates sensory quality of cooked meat products. It causes less change in the sensory properties of dry cured than cooked meat products while fermented sausage is least affected. The higher fluence applied significantly changes the instrumental color values of meat, poultry, game and meat products. The use of ILP on seafood regarding its influence on sensory quality is promising
On the nucleus of the Grassmann embedding of the symplectic dual polar space $DSp(2n,F)$.

Let  \geq 3$ and let $ be a field of characteristic 2. Let (2n,F)$ denote the dual polar space associated with the building of Type $ over $ and let $\mathcal{G}_{n-2}$ denote the $(n-2) of type $. Using the bijective correspondence between the points of $\mathcal{G}_{n-2}$ and the quads of (2n,F)$,
we construct a full projective embedding of $\mathcal{G}_{n-2}$ into the nucleus of the Grassmann embedding of (2n,F)$. This generalizes a result of Cardinali and Lunardon which contains an alternative proof of
this fact in the case when =3$ and $ is finite
Jet production rates in association with W and Z bosons in pp collisions at √s = 7 TeV

Journal of High Energy Physics 2012.1 (2012): 010 reproduced by permission of Scuola Internazionale Superiore di Studi Avanzati (SISSA)Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMMeasurements of jet production rates in association with W and Z bosons for jet transverse momenta above 30 GeV are reported, using a sample of proton-proton collision events recorded by CMS at √s = 7TeV, corresponding to an integrated luminosity of 36 pb -1. The study includes the measurement of the normalized inclusive rates of jets σ(V+ ≥ n jets)/σ(V), where V represents either a W or a Z. In addition, the ratio of W to Z cross sections and the W charge asymmetry as a function of the number of associated jets are measured. A test of scaling at √s = 7TeV is also presented. The measurements provide a stringent test of perturbative-QCD calculations and are sensitive to the possible presence of new physics. The results are in agreement with the predictions of a simulation that uses explicit matrix element calculations for final states with jet
Ruling out four-neutrino oscillation interpretations of the LSND

Prompted by recent solar and atmospheric data, we re-analyze the four-neutrino description of current global neutrino oscillation data, including the LSND evidence for oscillations. The higher degree of rejection for non-active solar and atmospheric oscillation solutions implied by the SNO neutral current result as well as by the latest 1489-day Super-K atmospheric neutrino data allows us to rule out (2+2) oscillation schemes proposed to reconcile LSND with the rest of current neutrino oscillation data. Using an improved goodness of fit (gof) method especially sensitive to the combination of data sets we obtain a gof of only 1.6 times 10^{-6} for (2+2) schemes. Further, we re-evaluate the status of (3+1) oscillations using two different analyses of the LSND data sample. We find that also (3+1) schemes are strongly disfavoured by the data. Depending on the LSND analysis we obtain a gof of 5.6 times 10^{-3} or 7.6 times 10^{-5}. This leads to the conclusion that all four-neutrino descriptions of the LSND anomaly, both in (2+2) as well as (3+1) realizations, are highly disfavoured. Our analysis brings the LSND hint to a more puzzling status
An Analytic Method for $S$-Expansion involving Resonance and Reduction

In this paper we describe an analytic method able to give the multiplication
table(s) of the set(s) involved in an $S$-expansion process (with either
resonance or $0_S$-resonant-reduction) for reaching a target Lie (super)algebra
from a starting one, after having properly chosen the partitions over subspaces
of the considered (super)algebras. This analytic method gives us a simple set
of expressions to find the partitions over the set(s) involved in the process.
Then, we use the information coming from both the initial (super)algebra and
the target one for reaching the multiplication table(s) of the mentioned
set(s). Finally, we check associativity with an auxiliary computational
algorithm, in order to understand whether the obtained set(s) can describe
semigroup(s) or just abelian set(s) connecting two (super)algebras. We also
give some interesting examples of application, which check and corroborate our
analytic procedure and also generalize some result already presented in the
literature.Comment: v3, 47 pages, misprints corrected in Fortschritte der Physik,
  Published online 7 November 201
Lived experiences of routine antenatal dietetic services among women with obesity: A qualitative phenomenological study

Midwifery; Volume 49, June 2017, Pages 47-53Objective\ud
\ud
To understand the lived experiences and views of being referred to an antenatal dietetic service from the perspective of pregnant women with obesity.\ud
Design\ud
\ud
A qualitative, interpretive approach using one-to-one in-depth interviews to explore the lived experience of pregnant women with obesity following referral to an antenatal dietetics service. Thematic content analysis was carried out by two researchers independently to develop data-driven themes.\ud
Setting\ud
\ud
One NHS Trust maternity and dietetic services, North East England, UK\ud
Participants\ud
\ud
Fifteen pregnant women with a booking body mass index ≥30 kg/m2 attending an obesity-specific antenatal dietetic service. All women were White, parity between 0–2, and BMI range 30–51 kg/m2.\ud
Findings\ud
\ud
Four themes were identified within this concept. 1) Women's overall experience of the service: experiences were predominately positive with only two negative cases identified. 2) Process of referral: women placed importance on informative and in-person communication about the service, with health professionals, at the point of referral. 3) Delivery of the service: dietitians were considered to be the experts and women wanted more frequent contact. 4) Content of the service: tailored advice enabled behaviour change, and women desired increased physical activity support and weight monitoring.\ud
Key conclusions\ud
\ud
Women reported an overall positive experience and thought that dietitians were the expert health professionals to support them. Women in this study felt that tailoring advice specific to their personal circumstances helped them implement changes, and had a strong interest in the nutritional benefits for fetal development. Women considered weight monitoring to be a positive element of the service; however, further research is required given the limited and conflicting evidence-base.\ud
Implications for practice\ud
\ud
It is important to incorporate women's experiences in the development and delivery of antenatal weight management services to facilitate person-centred care. Communication by health professionals at the point of referral is particularly important to provide accurate expectations of services and to reduce anxieties. Dietitians are considered to be appropriate experts to deliver these services, although they may need additional support to address women's physical activity needs in pregnancy