pinecone/core-2020-05-10-deduplication huggingface dataset:
Preservative Approach to Study Encased Archaeological Artefacts

International audienceWe propose a workflow based on a combination of computed tomography, 3D images and 3D printing to analyse different archaeological material dating from the Iron Age, a weight axis, a helical piece, and a fibula. This workflow enables a preservative analysis of the artefacts that are unreachable because encased either in stone, corrosion or ashes. Computed tomography images together with 3D printing provide a rich toolbox for archaeologist work allowing to access a tangible representation of hidden artefacts. These technologies are combined in an efficient, affordable and accurate workflow compatible with Preventive archaeology constraints
The role of structural inheritance in oblique rifting: insights from analogue models and application to the Gulf of Aden

International audienceThe geometry and kinematics of rifts are strongly controlled by pre-existing structures that may be present in both the crust and the mantle lithosphere. In the Gulf of Aden, the Tertiary oblique rift developed through inherited Mesozoic extensional basins that trend orthogonal to the direction of Oligo-Miocene divergence. Such inheritance may produce lateral variations in crustal thickness and thus in rheology of the crust and mantle lithosphere. How can such variations influence the present-day geometry of oblique rifts? May they locally overcome the impact of the oblique rheological weaknesses that in certain cases control the overall trend of the rift system? Moreover, we observe that major fracture zones systematically crosscut the inherited basins: may such inheritance influence the localization of major fracture zones by shifting the initial spreading centers? The brittle-ductile multilayer analogue models presented in this contribution reproduce oblique rifts. We tested the effect of an initial oblique weakness in the lithospheric mantle (i.e. structural or thermal inheritance) by introducing an oblique rheological weakness, which is alternatively initially imposed or dismissed. We tested the effect of the orthogonal Mesozoic inheritance by adding an elongated thicker brittle mantle, orthogonal to the direction of extension, in two models. These models mainly show en-échelon patterns with orthogonal faults and few rift-parallel faults (parallel to the rift obliquity), suggesting that the inherited orthogonal discontinuity is more influential than the oblique weakness in the lithospheric mantle. These results suggest that the presence in the lithosphere of an inherited basin could constitute a barrier to the deformation and sufficiently offset the spreading centers to lead to independent rift systems separated by major fracture faults. Moreover, the genetic nature of the obliquity (boundaries-driven or inherited) could control the length of the transform offset between two spreading centers and thus, the length of the future transform margin (continental domain affected by a transform fault)
Analysis of prophages harbored by the human-adapted subpopulation of Staphylococcus aureus CC398

Supplementary data (ANNEX)International audienceStaphylococcus aureus clonal complex 398 is a livestock-associated pathogen that poses a worldwide threat because of its ability to colonize and infect both humans and animals. We used high-resolution whole-genome microarrays, prophage profiling, immune evasion cluster characterization and whole-genome sequencing to investigate the roles of prophages in the emerging human-adapted subpopulation of CC398 that has been associated with invasive infections in humans living in animal-free environments. We characterized one phage and two prophages specifically harbored by CC398 isolates belonging to the emerging subpopulation. We introduced the phage into permissive prophage-free isolates. We investigated the effects of lysogeny on the host ability to resist further phage infection and transformation, to acquire the capacity to invade human cells, and to express virulence factors encoded by prophages. We report evidence of a defective ϕMR11-like helper prophage, named StauST398-5pro, specifically associated with the emerging non-LA CC398 subpopulation. StauST398-5pro confers substantial protection against horizontal genetic transfer to its host. It interacts with a human-associated β-converting prophage encoding immune-modulating proteins such that virulence genes are expressed during stress situations. Our findings provide insight into the role of phages in the expression of virulence and in the spread of genetic information among new host-adapted S. aureus isolates. We demonstrate that functional prophage elements can condition host specificity and confer new virulence traits on emerging intra-species clones of bacteria
A maximal entropy stochastic process for a timed automaton

International audienceSeveral ways of assigning probabilities to runs of timed automata (TA) have been proposed recently. When only the TA is given, a relevant question is to design a probability distribution which represents in the best possible way the runs of the TA. This question does not seem to have been studied yet. We give an answer to it using a maximal entropy approach. We introduce our variant of stochastic model, the stochastic process over runs which permits to simulate random runs of any given length with a linear number of atomic operations. We adapt the notion of Shannon (continuous) entropy to such processes. Our main contribution is an explicit formula defining a process $Y^*$ which maximizes the entropy. This formula is an adaptation of the so-called Shannon-Parry measure to the timed automata setting. The process $Y^*$ has the nice property to be ergodic. As a consequence it has the asymptotic equipartition property and thus the random sampling wrt. $Y^*$ is quasi uniform
Assessing in near real time the impact of the April 2010 Eyjafjallajökull ash plume on air quality

5 p.International audienceThe eruption of the Eyjafjallajökull in April 2010 led to the injection in the troposphere of an important quantity of volcanic ash whose advection towards densely populated areas raised serious concerns regarding potential impacts on air quality. Here we investigate to what extent air quality in France was altered using exclusively quantitative data that was available in near real-time. We rely on a combination of atmospheric dispersion modelling, ground-based remote sensing, and chemical characterization of airborne particles. One week after the onset of the eruption we were able to conclude that the Eyjafjallajökull ash plume was locally responsible for an increase of up to 30 +/- 10 µgm-3 of total PM10 (particulate matter finer than 10 µm) that reached 65 mg m-3 on 18 and 19 April 2010. The methodology presented in this letter offers promising perspectives in terms of emergency response strategy when facing such unforeseen atmospheric dispersion events
Optimal control models and elicitation of attitudes towards climate damages

International audienceThis paper examines the consequences of various attitudes towards climate damages through a family of stochastic optimal control models (RESPONSE): cost-efficiency for a given temperature ceiling; cost-benefit analysis with a "pure preference for current climate regime" and full cost-benefit analysis. The choice of a given proxy of climate change risks is actually more than a technical option. It is essentially motivated by the degree of distrust regarding the legitimacy of an assessment of climate damages and the possibility of providing in due time reliable and non controversial estimates. Our results demonstrate that a) for early decades abatement, the difference between various decision-making frameworks appears to matter less than the difference between stochastic and non stochastic approach given the cascade of uncertainty from emissions to damages; b) in a stochastic approach, the possibility of non-catastrophic singularities in the damage function is sufficient to significantly increase earlier optimal abatements; c) a window of opportunity for action exists up to 2040: abatements further delayed may induce significant regret in case of bad news about climate response or singularities in damages
Explosivity Conditions of Aqueous Solutions

International audienceThis paper focuses on the conditions for explosive boiling and gas exsolution of aqueous solutions from a thermodynamic point of view. Indeed, the kinetic nature of these processes, hence their explosivity, can be assessed by considering their relation with the spinodal curve of these liquids. First, the concepts of mechanical and diffusion spinodals are briefly described, which allows us to introduce the notions of superspinodal (explosive) transformations and subspinodal (non-explosive) ones. Then, a quantitative study of spinodal curves is attempted for the binary systems H2O–CO2 and H2O–NaCl using equations of state having a strong physical basis. It is shown that dissolved gaseous components and electrolytes have an antagonist effect: dissolved volatiles (like CO2) tend to shift the superspinodal region towards lower temperatures, whereas electrolytes (like NaCl) tend to extend the metastable field towards higher temperatures
Stiffness modeling of robotic manipulator with gravity compensator

International audienceThe paper focuses on the stiffness modeling of robotic manipulators with gravity compensators. The main attention is paid to the development of the stiffness model of a spring-based compensator located between sequential links of a serial structure. The derived model allows us to describe the compensator as an equivalent non-linear virtual spring integrated in the corresponding actuated joint. The obtained results have been efficiently applied to the stiffness modeling of a heavy industrial robot of the Kuka family
Understanding Design Patterns Density with Aspects: A Case Study in JHotDraw using AspectJ

International audienceDesign patterns offer solutions to common engineering prob- lems in programs [1]. In particular, they shape the evolution of program elements. However, their implementations tend to vanish in the code: thus it is hard to spot them and to understand their impact. The prob- lem becomes even more difficult with a "high density of pattern": then the program becomes easy to evolve in the direction allowed by patterns but hard to change [2]. Aspect languages offer new means to modular- ize elements. Implementations of object-oriented design patterns with AspectJ have been proposed [3]. We aim at testing the scalability of such solutions in the JHotDraw framework. We first explore the impact of density on pattern implementation. We show how AspectJ helps to reduce this impact. This unveils the principles of aspects and AspectJ to control pattern density
Knowledge governance within clusters: the case of small firms

International audienceDespite the vast literature on knowledge management, little research has addressed the specificities of knowledge integration at the cluster level. Moreover, the literature on clusters has not focused on the role that governance may play in knowledge management. Anchored in a knowledge-based perspective, this paper aims at bridging the two fields, filling the gap by analysing the role of cluster governance in knowledge management. An empirical study of two small French firm clusters was carried out based on 29 interviews. The data analysis consisted essentially in content analysis. The clusters studied were characterized by distinct knowledge management processes. In both cases, governance was necessary in order to support knowledge integration by member firms. Our results suggest that establishing an initial common knowledge base seems to be a prerequisite in order for the external knowledge identification and acquisition processes to take place. The activist role played by governance also seems more efficient than that of a broker. We discuss these results and their implications for policy-makers and cluster members
Long time behaviour of a stochastic nanoparticle

International audienceIn this article, we are interested in the behaviour of a single ferromagnetic mono-domain particle submitted to an external field with a stochastic perturbation. This model is the first step toward the mathematical understanding of thermal effects on a ferromagnet. In a first part, we present the stochastic model and prove that the associated stochastic differential equation is well defined. The second part is dedicated to the study of the long time behaviour of the magnetic moment and in the third part we prove that the stochastic perturbation induces a non reversibility phenomenon. Last, we illustrate these results through numerical simulations of our stochastic model. The main results presented in this article are the rate of convergence of the magnetization toward the unique stable equilibrium of the deterministic model. The second result is a sharp estimate of the hysteresis phenomenon induced by the stochastic perturbation (remember that with no perturbation, the magnetic moment remains constant)
Three-dimensional linear instability in pressure-driven two-layer channel flow of a Newtonian and a Herschel-Bulkley fluid

The three-dimensional linear stability characteristics of pressure-driven two-layer channel flow are considered, wherein a Newtonian fluid layer overlies a layer of a Herschel-Bulkley fluid. We focus on the parameter ranges for which Squire's theorem for the two-layer Newtonian problem does not exist. The modified Orr-Sommerfeld and Squire equations in each layer are derived and solved using an efficient spectral collocation method. Our results demonstrate the presence of three-dimensional instabilities for situations where the square root of the viscosity ratio is larger than the thickness ratio of the two layers; these &quot;interfacial&quot; mode instabilities are also present when density stratification is destabilizing. These results may be of particular interest to researchers studying the transient growth and nonlinear stability of two-fluid non-Newtonian flows. We also show that the &quot;shear&quot; modes, which are present at sufficiently large Reynolds numbers, are most unstable to two-dimensional disturbances
Thalamocortical relationships and network synchronization in a new genetic model "in mirror" for absence epilepsy.

International audienceElectroencephalographic generalized spike and wave discharges (SWD), the hallmark of human absence seizures, are generated in thalamocortical networks. However, the potential alterations in these networks in terms of the efficacy of the reciprocal synaptic activities between the cortex and the thalamus are not known in this pathology. Here, the efficacy of these reciprocal connections is assessed in vitro in thalamocortical slices obtained from BS/Orl mice, which is a new genetic model of absence epilepsy. These mice show spontaneous SWD, and their features can be compared to that of BR/Orl mice, which are free of SWD. In addition, since gap junctions may modulate the efficacy of these connections, their implications in pharmacologically-induced epileptiform discharges were studied in the same slices. The thalamus and neocortex were independently stimulated and the electrically-evoked responses in both structures were recorded from the same slice. The synaptic efficacy of thalamocortical and corticothalamic connections were assessed by measuring the dynamic range of synaptic field potential changes in response to increasing stimulation strengths. The connection efficacy was weaker in epileptic mice however, this decrease in efficacy was more pronounced in thalamocortical afferents, thus introducing an imbalance in the reciprocal connections between the cortex and thalamus. However, short-term facilitation of the thalamocortical responses were increased in epileptic mice compared to non-epileptic animals. These features may favor occurrence of rhythmical activities in thalamocortical networks. In addition, carbenoxolone (a gap junction blocker) decreased the cumulative duration of 4-aminopyridine-induced ictal-like activities, with a slower time course in epileptic mice. However, the 4-aminopyridine-induced GABA-dependent negative potentials, which appeared to trigger the ictal-like activities, remained. Our results show that the balance of the reciprocal connections between the thalamus and cortex is altered in favor of the corticothalamic connections in epileptic mice, and suggest that gap junctions mediate a stronger cortical synchronization in this strain
Rapid cortical oscillations and early motor activity in premature human neonate.

International audienceDelta-brush is the dominant pattern of rapid oscillatory activity (8-25 Hz) in the human cortex during the third trimester of gestation. Here, we studied the relationship between delta-brushes in the somatosensory cortex and spontaneous movements of premature human neonates of 29-31 weeks postconceptional age using a combination of scalp electroencephalography and monitoring of motor activity. We found that sporadic hand and foot movements heralded the appearance of delta-brushes in the corresponding areas of the cortex (lateral and medial regions of the contralateral central cortex, respectively). Direct hand and foot stimulation also reliably evoked delta-brushes in the same areas. These results suggest that sensory feedback from spontaneous fetal movements triggers delta-brush oscillations in the central cortex in a somatotopic manner. We propose that in the human fetus in utero, before the brain starts to receive elaborated sensory input from the external world, spontaneous fetal movements provide sensory stimulation and drive delta-brush oscillations in the developing somatosensory cortex contributing to the formation of cortical body maps
Demise of a harbor: a geochemical chronicle from Ephesus

International audiencea b s t r a c t At the end of the first century BC, Ephesus became the Roman capital of Asia Minor and the most important commercial, religious, and cultural center of the region. In order to evaluate the status of anthropogenic fluxes in the port of Ephesus, a 12 m long sediment core drilled in the Roman basin was investigated to shed light on the paleo-environmental evolution of the harbor using grain size distri-bution analysis, 14 C ages, major and trace element geochemistry, and Pb isotope compositions. With the help of complementary sedimentological data and Principal Component Analysis, five distinct units were identified which, together, reflect the different stages of water history in the harbor. Among the major disruptive events affecting the port were earthquakes and military events, both of which were partic-ularly effective at destroying the water distribution system. Seasonal floods of the Cayster River (Küçük Menderes) were the major source of the silt that progres-sively infilled the harbor. Silting in was further enhanced by the westward migration of the river mouth. A single major disruptive event located at 550 cm core depth and heralding the development of anoxia in the harbor marks the end of the dynamic regime that otherwise controlled the harbor water throughout the Roman Empire period. This remarkable event may correspond to a major disruption of the aqueduct system or to a brutal avulsion of the Cayster River bed. It clearly represents a major disturbance in the history of life at Ephesus. It is poorly dated, but probably occurred during the reign of Augustus or shortly after. Lead isotope and trace metal evidence suggest that in the four bottom units pollution was subdued with respect to other Pb metal inputs, presumably those from aqueducts and natural karstic springs. Near the top of the core, which coincides with harbor abandonment and the more recent period, anthropogenic Pb contam-ination is clearly visible in both Pb abundances and isotopic compositions
TSF Experiment for comparision of high Reynold's number turbulence in He I and He II : ﬁrst results

International audienceSuperfluid turbulence (TSF) project uses liquid helium for the fundamental study of turbulent phenomena behind a passive grid and is able to work both in HeI and in HeII. Local and semi-local instrumentation was developed specifically for the purpose of this experiment(e.g. sub-micrometer anemometer, total head pressure tube and second sound tweezer). The difficulties encountered with this local and fragile instrumentation are discussed. Global characterization of the flow is presented including velocity, pressure, temperature stability and turbulence intensity. Finally, first results obtained with semi local measurements (total head pressure tube and second sound tweezer) both in the two phases of helium are presented
GDS: An Architecture Proposal for a grid Data-Sharing Service

Also available as an INRIA Research Report 5593: http://www.inria.fr/rrrt/rr-5593.html/http://www.springer.comInternational audienceGrid computing has recently emerged as a response to the growing demand for resources (processing power, storage, etc.) exhibited by scientific applications. We address the challenge of sharing large amounts of data on such infrastructures, typically consisting of a federation of node clusters. We claim that storing, accessing, updating and sharing such data should be considered by applications as an external service. We propose an architecture for such a service, whose goal is to provide transparent access to mutable data, while enhancing data persistence and consistency despite node disconnections or failures. Our approach leverages on weaving together previous results in the areas of distributed shared memory systems, peer-to-peer systems, and fault-tolerant systems
The region of the Strandja Sill (North Turkey) and the Messinian events

International audienceThe two sides of the Strandja Sill show a highly discontinuous stratigraphic succession since the Late Oligocene. This area, together with the Sea of Marmara Basin, is usually proposed as the gateway for the Paratethyan freshwaters and organisms that constituted the Lago Mare facies in the Mediterranean Sea during the Messinian Salinity Crisis (MSC). Our investigations involving new field observations and datings, together with previous studies, suggest that the sill has possibly experienced such a connection at around 8 Ma, i.e. significantly before the crisis. The proposal of a sea-level drop of the Black Sea before 7 Ma is not supported by our data on dinoflagellate cysts. Consistency of calcareous nannofossil succession at DSDP Site 380 is reinforced, allowing to reassert that subaerial erosion impacted both the southwestern Black Sea and the central Marmara – Dardanelles area during the peak of the MSC. At that time, this region was crossed by two oppositely directed fluvial networks, further supporting the absence of a marine gateway through the Strandja Sill. It is concluded that none of the Lago Mare events recorded in the Mediterranean during the MSC were the consequence of the passage of Paratethyan waters and organisms through this area. In the Black Sea, the well-dated Messinian fluvial erosion can be followed offshore. The overlying prograding deltaic deposits attest to a fast marine reflooding after the crisis. This constitutes a comprehensive erosion-sedimentation model in an area intensively explored for hydrocarbons