pinecone/core-2020-05-10-deduplication huggingface dataset:
Mesonic and binding contributions to the EMC effect in a relativistic many-body approach

We revise the conventional nuclear effects of Fermi motion, binding and pionic effects in deep inelastic lepton scattering using a relativistic formalism for an interacting Fermi sea and the local density approximation to translate results from nuclear matter to finite nuclei. In addition we also consider effects from rho-meson renormalization in the nucleus. The use of nucleon Green's functions in terms of their spectral functions offers a precise way to account for Fermi motion and binding. On the other hand the use of many body Feynman diagrams in a relativistic framework allows one to avoid using prescriptions given in the past to introduce relativistic corrections in a non relativistic formalism. We show that with realistic nucleon spectral functions and meson nucleus selfenergies one can get a reasonable description of the EMC effect for x > 0.15, outside the shadowing region
NINE-PROFILE AND NINE-SEGMENT TEMPERATURE PROGRAMMER FOR MASHING APPARATUS

Mashing is a process of converting the grain starch into fermentable sugar by activating the malt enzymes using a hot-water steeping process. A microcontroller-based nine-profile, nine-segment temperature programmer and four-channel temperature and rpm (rotations per minute) display system for the mashing apparatus has been designed and implemented using a PIC 16F887 microcontroller. In this apparatus, a pulse width modulation (PWM)-based programmable AC voltage controller has been designed to vary mash tub temperature at required rate, and the resistance temperature detector (RTD) PT100 has been used to measure the temperature of the mash tub and sample. The software for the microcontroller has been developed using C language to set the end temperature and time of the nine segments of nine temperature profiles through the keypad and also to implement the proportional integral and derivative (PID) controller to control the temperature of the mash tub as per user settings
Coupling of $t\bar t$ and $\gamma\gamma$ with a strongly interacting
  Electroweak Symmetry Breaking Sector

We report the coupling of an external $\gamma\gamma$ or $t\bar t$ state to a
strongly interacting EWSBS satisfying unitarity. We exploit perturbation theory
for those coupling of the external state, whereas the EWSBS is taken as
strongly interacting. We use a modified version of the IAM unitarization
procedure to model such a strongly interacting regime. The matrix elements
$V_LV_L\to V_LV_L$, $V_LV_L\leftrightarrow hh$, $hh\to hh$,
$V_LV_L\leftrightarrow\{\gamma\gamma,t\bar t\}$, and
$hh\leftrightarrow\{\gamma\gamma,t\bar t\}$ are all computed to NLO in
perturbation theory with the Nonlinear Effective Field Theory of the EWSBS,
within the Equivalence Theorem. This allows us to describe resonances of the
electroweak sector that may be found at the LHC and their effect on other
channels such as $\gamma\gamma$ or $t\bar t$ where they may be discovered.Comment: 9 pages, 3 figures. Contributions to the Procs. of the XIIth Quark
  Confinement and the Hadron Spectrum, Thessaloniki, Greece, August 201
Search for heavy resonances decaying to tau lepton pairs in
  proton-proton collisions at sqrt(s) = 13 TeV

A search for heavy resonances that decay to tau lepton pairs is performed
using proton-proton collisions at sqrt(s) = 13 TeV. The data were collected
with the CMS detector at the CERN LHC and correspond to an integrated
luminosity of 2.2 inverse femtobarns. The observations are in agreement with
standard model predictions. An upper limit at 95% confidence level on the
product of the production cross section and branching fraction into tau lepton
pairs is calculated as a function of the resonance mass. For the sequential
standard model, the presence of Z' bosons decaying into tau lepton pairs is
excluded for Z' masses below 2.1 TeV, extending previous limits for this final
state. For the topcolor-assisted technicolor model, which predicts Z' bosons
that preferentially couple to third-generation fermions, Z' masses below 1.7
TeV are excluded, representing the most stringent limit to date.Comment: Replaced with the published version. Added the journal reference and
  DOI. All the figures and tables can be found at
  http://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-16-008/index.htm
The effect of motor load on executive functioning in developmental coordination disorder

Previous research has reported mixed findings regarding executive function (EF) abilities in developmental coordination disorder (DCD), which is diagnosed on the basis of significant impairments in motor skills. The current study aimed to assess whether these differences in study outcomes could result from the relative motor loads of the tasks used to assess EF in DCD. Children with DCD had significant difficulties on measures of inhibition and planning compared to a control group, although there were no significant correlations between motor skills and EF task performance in either group. The complexity of the response, as well as the component skills required in EF tasks, should be considered in future research to ensure easier comparison across studies and a better understanding of EF in DCD over development
Cell type-specific profiling of protein-DNA interactions without cell isolation using Targeted DamID with next-generation sequencing

The ability to profile transcription and chromatin binding in a cell type-specific manner is a powerful approach for understanding cell fate specification and cellular function in multicellular organisms. We recently developed Targeted DamID (TaDa) to enable genome-wide, cell-type-specific profiling of DNA- and chromatin-binding proteins in vivo without cell isolation. As a Protocol Extension, this article describes substantial modifications to an existing Protocol and offers additional applications. TaDa builds upon DamID, a technique for detecting genome-wide DNA binding profiles of proteins, by coupling it with the GAL4 system in Drosophila to enable both temporal and spatial resolution. TaDa ensures that Dam-fusion proteins are expressed at very low levels, avoiding toxicity and potential artefacts from over-expression. The modifications to the core DamID technique presented here also increase the speed of sample processing and throughput, and adapt the method to Nextgeneration Sequencing technology. TaDa is robust, reproducible, and highly sensitive. Compared to other methods for cell-type specific profiling, the technique requires no cell-sorting, crosslinking or antisera, and binding profiles can be generated from as few as 10,000 total induced cells. By profiling the genome-wide binding of RNA polymerase II, TaDa can also identify transcribed genes in a cell type-specific manner. Here we describe a detailed protocol for carrying out TaDa experiments and preparing the material for next generation sequencing. Although we developed TaDa in Drosophila, it should be easily adapted to other organisms with an inducible expression system. Once transgenic animals are obtained, the entire experimental procedure ??? from collecting tissue samples to generating sequencing libraries ??? can be accomplished within 5 days
Effective crustal permeability controls fault evolution : an integrated structural, mineralogical and isotopic study in granitic gneiss, Monte Rosa, northern Italy

Two dextral faults within granitic gneiss in the Monte Rosa nappe, northern Italy reveal key differences in their evolution controlled by evolving permeability and water/rock reactions. The comparison reveals that identical host rock lithologies develop radically different mineralogies within the fault zones, resulting in fundamentally different deformation histories. Oxygen and hydrogen isotope analyses coupled to microstructural characterisation show that infiltration of meteoric water occurred into both fault zones. The smaller Virgin Fault shows evidence of periodic closed system behaviour, which promoted the growth of hydrothermal K-feldspar, whilst the more open system behaviour of the adjacent Ciao Ciao Fault generated a weaker muscovite-rich fault core, which promoted a step change in fault evolution. Effective crustal permeability is a vital control on fault evolution and, coupled to the temperature (i.e. depth) at which key mineral transformations occur, is probably a more significant factor than host rock strength in controlling fault development. The study suggests that whether a fault in granitic basement grows into a large structure may be largely controlled by the initial hydrological properties of the host rocks. Small faults exposed at the surface may therefore be evolutionary “dead-ends” that typically do not represent the early stages in the development of larger faults
Disassembly of a Medial Transenvelope Structure by Antibiotics during Intracellular Division.

Chlamydiales possess a minimal but functional peptidoglycan precursor biosynthetic and remodeling pathway involved in the assembly of the division septum by an atypical cytokinetic machine and cryptic or modified peptidoglycan-like structure (PGLS). How this reduced cytokinetic machine collectively coordinates the invagination of the envelope has not yet been explored in Chlamydiales. In other Gram-negative bacteria, peptidoglycan provides anchor points that connect the outer membrane to the peptidoglycan during constriction using the Pal-Tol complex. Purifying PGLS and associated proteins from the chlamydial pathogen Waddlia chondrophila, we unearthed the Pal protein as a peptidoglycan-binding protein that localizes to the chlamydial division septum along with other components of the Pal-Tol complex. Together, our PGLS characterization and peptidoglycan-binding assays support the notion that diaminopimelic acid is an important determinant recruiting Pal to the division plane to coordinate the invagination of all envelope layers with the conserved Pal-Tol complex, even during osmotically protected intracellular growth
Search for narrow high-mass resonances in proton–proton collisions at √s = 8 TeV decaying to a Z and a Higgs boson

A search for a narrow, high-mass resonance decaying into Z and Higgs (H) bosons is presented. The final state studied consists of a merged jet pair and a τ pair resulting from the decays of Z and H bosons, respectively. The analysis is based on a data sample of proton–proton collisions at a center-of-mass energy of 8 TeV, collected with the CMS experiment in 2012, and corresponding to an integrated luminosity of 19.7 fb[superscript −1]. In the resonance mass range of interest, which extends from 0.8 to 2.5 TeV, the Z and H bosons are produced with large momenta, which implies that the final products of the two quarks or the two τ leptons must be detected within a small angular interval. From a combination of all possible decay modes of the τ leptons, production cross sections in a range between 0.9 and 27.8 fb are excluded at 95% confidence level, depending on the resonance mass.United States. Dept. of EnergyNational Science Foundation (U.S.
Detecting frog calling activity based on acoustic event\ud
detection and multi-label learning

Frog population has been declining the past decade for habitat loss, invasive species, climate change, and so forth. Therefore, it is becoming ever more important to monitor the frog population. Recent advances in acoustic sensors make it possible to collect frog vocalizations over large spatio-temporal scale. Through the detection of frog calling activity with collected acoustic data, frog population can be predicted. In this paper we propose a novel method for detecting frog calling activity using acoustic event detection and multi-label learning. Here, frog calling activity consists of frog abundance and frog species richness, which denotes number of individual frog calls and number of frog species respectively. To be specific, each segmented recording is first transformed to a spectrogram. Then, acoustic event detection is used to calculate frog abundance. Meanwhile, those recordings without frog calls are filtered out. For frog species richness, three acoustic features, linear predictive coefficients, Mel-frequency Cepstral coefficients and wavelet-based features are calculated. Then, multi-label learning is used to predict frog species richness. Lastly, statistical analysis is used to reflect the relationship between frog calling activity (frog abundance and frog species richness) and weather variables. Experiment results show that our proposed method can accurately detect frog calling activity and reflect its relationship with weather variables
Genome-wide association for major depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

Background\ud
\ud
Major depressive disorder (MDD) is a disabling mood disorder and, despite a known heritable component, a large meta-analysis of GWAS revealed no replicable genetic risk variants. Given prior evidence of heterogeneity by age-at-onset (AAO) in MDD, we tested whether genome-wide significant risk variants for MDD could be identified in cases subdivided by AAO.\ud
\ud
Method\ud
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Discovery case-control GWASs were performed where cases were stratified using increasing/decreasing AAO-cutoffs; significant SNPs were tested in nine independent replication samples, giving a total sample of 22,158 cases and 133,749 controls for sub-setting. Polygenic score analysis was used to examine if differences in shared genetic risk exists between earlier and adult onset MDD with commonly co-morbid disorders of schizophrenia, bipolar disorder, Alzheimer’s disease, and coronary artery disease.\ud
\ud
Results\ud
\ud
We identify one replicated genome-wide significant locus associated with adult-onset (>27 years) MDD (rs7647854, OR=1.16, 95%CI=1.11-1.21, p=5.2x10-11). Using polygenic score analyses, we show that earlier-onset MDD is genetically more similar to schizophrenia and bipolar disorder than adult-onset.\ud
\ud
Conclusions\ud
\ud
We demonstrate that using additional phenotype data previously collected by genetic studies to tackle phenotypic heterogeneity in MDD can successfully lead to the discovery of genetic risk factor despite reduced sample size. Furthermore, our results suggest that the genetic susceptibility to MDD differs between adult- and earlier-onset MDD, with earlier-onset cases having a greater genetic overlap with schizophrenia and bipolar disorder
Are long gamma-ray bursts biased tracers of star formation? Clues from the host galaxies of the Swift/BAT6 complete sample of bright LGRBs II. Star formation rates and metallicities at z < 1

Aims. Long gamma-ray bursts (LGRBs) are associated with the deaths of massive stars and might therefore be a potentially powerful tool for tracing cosmic star formation. However, especially at low redshifts (z< 1.5) LGRBs seem to prefer particular types of environment. Our aim is to study the host galaxies of a complete sample of bright LGRBs to investigate the effect of the environment on GRB formation.\ud
Methods. We studied host galaxy spectra of the Swift/BAT6 complete sample of 14 z< 1 bright LGRBs. We used the detected nebular emission lines to measure the dust extinction, star formation rate (SFR), and nebular metallicity (Z) of the hosts and supplemented the data set with previously measured stellar masses M_*. The distributions of the obtained properties and their interrelations (e.g. mass-metallicity and SFR-M_* relations) are compared to samples of field star-forming galaxies.\ud
Results. We find that LGRB hosts at z< 1 have on average lower SFRs than if they were direct star formation tracers. By directly comparing metallicity distributions of LGRB hosts and star-forming galaxies, we find a good match between the two populations up to 12 +log (O/H)~8.4−8.5, after which the paucity of metal-rich LGRB hosts becomes apparent. The LGRB host galaxies of our complete sample are consistent with the mass-metallicity relation at similar mean redshift and stellar masses. The cutoff against high metallicities (and high masses) can explain the low SFR values of LGRB hosts. We find a hint of an increased incidence of starburst galaxies in the Swift/BAT6 z< 1 sample with respect to that of a field star-forming population. Given that the SFRs are low on average, the latter is ascribed to low stellar masses. Nevertheless, the limits on the completeness and metallicity availability of current surveys, coupled with the limited number of LGRB host galaxies, prevents us from investigating more quantitatively whether the starburst incidence is such as expected after taking into account the high-metallicity aversion of LGRB host galaxies
Search for anomalous production of prompt same-sign lepton pairs and pair-produced doubly charged Higgs bosons with root s = 8 TeV pp collisions using the ATLAS detector

A low-background inclusive search for new physics in events with same-sign dileptons is presented. The search uses proton-proton collisions corresponding to 20.3 fb⁻¹ of integrated luminosity taken in 2012 at a centre-of-mass energy of 8TeV with the ATLAS detector at the LHC. Pairs of isolated leptons with the same electric charge and large transverse momenta of the type e±e±, e±μ±, and μ±μ± are selected and their invariant mass distribution is examined. No excess of events above the expected level of Standard Model background is found. The results are used to set upper limits on the cross-sections for processes beyond the Standard Model. Limits are placed as a function of the dilepton invariant mass within a fiducial region corresponding to the signal event selection criteria. Exclusion limits are also derived for a specific model of doubly charged Higgs boson production.G. Aad ... P. Jackson ... L. Lee ... A. Petridis ... N. Soni ... M.J. White ... et al. (The ATLAS Collaboration
The VIMOS Public Extragalactic Redshift Survey (VIPERS). On the recovery of the count-in-cell probability distribution function

W.J.P. and R.T. acknowledge financial support from the European Research Council under the European Community’s Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement no. 202686.We compare three methods to measure the count-in-cell probability density function of galaxies in a spectroscopic redshift survey. From this comparison we found that, when the sampling is low (the averagenumber of object per cell is around unity), it is necessary to use a parametric method to model the galaxy distribution. We used a set of mock catalogues of VIPERS to verify if we were able to reconstruct the cell-count probability distribution once the observational strategy is applied. We find that, in the simulated catalogues, the probability distribution of galaxies is better represented by a Gamma expansion than a skewed log-normal distribution. Finally, we correct the cell-count probability distribution function from the angular selection effect of the VIMOS instrument and study the redshift and absolute magnitude dependency of the underlying galaxy density function in VIPERS from redshift 0.5 to 1.1. We found a very weak evolution of the probability density distribution function and that it is well approximated by a Gamma distribution, independently of the chosen tracers.Based on observations collected at the European Southern Observatory, Cerro Paranal, Chile, using the Very Large Telescope under programmes 182.A-0886 and partly 070.A-9007. Also based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences del'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products produced at TERAPIX and the Canadian Astronomy Data Centre aspart of the Canada-France-Hawaii Telescope Legacy Survey, a collaborative project of NRC and CNRS. The VIPERS web site is http://www.vipers.inaf.it/Publisher PDFPeer reviewe
Antisymmetric tensor fields in a generalized Randall–Sundrum scenario

AbstractBulk antisymmetric tensor fields of different ranks have been studied in the context of a generalized Randall–Sundrum model with a non-vanishing induced cosmological constant on the visible brane. It is shown that instead of the usual exponential suppression of the couplings of the zero modes of these bulk fields with the brane fermions in the original Randall–Sundrum model, here the couplings are proportional to the brane cosmological constant. Thus in an era of large cosmological constant these fields have significant role in physical phenomena because of their enhanced couplings with the visible brane fermions
Muon-induced background to proton decay in the p→K+ν decay channel with large underground liquid argon TPC detectors

AbstractLarge liquid argon TPC detector programs such as LBNE and LAGUNA-LBNO will be able to make measurements of the proton lifetime which will outperform Cherenkov detectors in the proton decay channel p→K+ν. At the large depths which are proposed for such experiments, a non-negligible source of isolated charged kaons may be produced in the showers of cosmogenic muons. We present an estimate of the cosmogenic muon background to proton decay in the p→K+ν channel. The simulation of muon transport to a depth of 4 km w.e. is performed in the MUSIC framework and the subsequent propagation of muons and secondary particles in the vicinity of a cylindrical 20 kt LAr target is performed using Geant4. An exposure time of 100 years is considered, with a rate of <0.0012 events/kt/year at 90% CL predicted from our simulations
Efficacy of pulmonary rehabilitation in chronic respiratory failure (CRF) due to chronic obstructive pulmonary disease (COPD): The Maugeri Study

SummaryWhile the effectiveness of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) is well established, its effectiveness in the most severe category of COPD, i.e. patients with chronic respiratory failure (CRF), is less well known.ObjectiveTo verify the effects of PR in patients with CRF, and compare the level of improvement with PR in these patients to that of COPDs not affected by CRF.MethodsA multi-centre study was carried out on COPD patients with versus without CRF. The PR program included educational support, exercise training, and nutritional and psychological counselling. Lung function, arterial gases, walk test (6MWT), dyspnoea (MRC; BDI/TDI), and quality of life (MRF28; SGRQ) were evaluated.ResultsThousand forty seven consecutive COPD inpatients (327 with CRF) were evaluated. In patients with CRF all parameters improved after PR (0.001). Mean changes: FEV1, 112ml; PaO2, 3.0mmHg; PaCO2, 3.3mmHg; 6MWT, 48m; MRC, 0.85units; MRF28 total score, 11.5units. These changes were similar to those observed in patients without CRF.ConclusionsThis study, featuring the largest cohort so far reported in the literature, shows that PR is equally effective in the more severe COPD patients, i.e. those with CRF, and supports the prescription of PR also in these patients