pinecone/core-2020-05-10-deduplication huggingface dataset:
A high-resolution palaeoclimate record for the last 4800 years from lake la Brava, SE pampas plains, Argentina

AbstractClimatic changes are reflected in variations of different parameters. Sequences of lake sediments are good sources of this information because they provide continuous and detailed records of palaeoclimatic changes. In order to determine the changes in climate in SE Pampas plain, in this paper we present a series of rock magnetic studies performed on a bottom core collected from Lake La Brava (Argentina).In order to establish lake level variations, we also measure total sulphur, organic and inorganic carbon (TS, TOC and TIC) content, alkaline elements, light and heavy metals and changes in vegetation communities. Five radiocarbon age determinations were made from samples of organic-rich clay and calibrated ages were calculated. The averaged sediment accumulation rate is 1.3mm/yr and the sequence represents a temporal extent of about 4800 calibrated years before the present (cal. BP).The main aim was to reconstruct the hydrological balance of the lake, the changes in erosional strength and sediment supply within the catchment area since the Middle Holocene, and to explore the extent to which these may be linked to changes in climate and/or human activities. The results of this work and previous studies suggest periodic changes from cooler to warmer and humid conditions. Relationships between submerged and emergent plants are consistent with the behaviour of magnetic susceptibility. TOC changes suggest wet environment during magnetic enhancement. Floods and lower lake level events were identified in detail. Changes in sediment contribution and depositional processes for the last 50cal. BP are caused by human impact, particularly by the use of natural resources
Signature of an h1 state in the J/ψ→ηh1→ηK⁎0K¯⁎0 decay

AbstractThe BES data on the J/ψ→ηK⁎0K¯⁎0 reaction show a clear enhancement in the K⁎0K¯⁎0 mass distribution close to the threshold of this channel. Such an enhancement is usually a signature of an L=0 resonance around threshold, which in this case would correspond to an h1 state with quantum numbers IG(JPC)=0−(1+−). A state around 1800MeV results from the interaction of the K⁎K¯⁎ using the local hidden gauge approach. We show that the peak observed in J/ψ→ηK⁎0K¯⁎0 naturally comes from the creation of this h1 state with mass and width around 1830MeV and 110MeV, respectively. A second analysis, model independent, corroborates the first result, confirming the relationship of the enhancement in the invariant mass spectrum with the h1 resonance
Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification

AbstractMammalian Host-Cell Factor 1 (HCF-1), a transcriptional co-regulator, plays important roles during the cell-division cycle in cell culture, embryogenesis as well as adult tissue. In mice, HCF-1 is encoded by the X-chromosome-linked Hcfc1 gene. Induced Hcfc1cKO/+ heterozygosity with a conditional knockout (cKO) allele in the epiblast of female embryos leads to a mixture of HCF-1-positive and -deficient cells owing to random X-chromosome inactivation. These embryos survive owing to the replacement of all HCF-1-deficient cells by HCF-1-positive cells during E5.5 to E8.5 of development. In contrast, complete epiblast-specific loss of HCF-1 in male embryos, Hcfc1epiKO/Y, leads to embryonic lethality. Here, we characterize this lethality. We show that male epiblast-specific loss of Hcfc1 leads to a developmental arrest at E6.5 with a rapid progressive cell-cycle exit and an associated failure of anterior visceral endoderm migration and primitive streak formation. Subsequently, gastrulation does not take place. We note that the pattern of Hcfc1epiKO/Y lethality displays many similarities to loss of β-catenin function. These results reveal essential new roles for HCF-1 in early embryonic cell proliferation and development
Exploiting symmetries within constraint satisfaction search☆☆This paper is an extended and updated version of [16], presented at the IJCAI-99 conference.

AbstractSymmetry often appears in real-world constraint satisfaction problems, but strategies for exploiting it are only beginning to be developed. Here, a framework for exploiting symmetry within depth-first search is proposed, leading to two heuristics for variable selection and a domain pruning procedure. These strategies are then applied to two highly symmetric combinatorial problems, namely the Ramsey problem and the generation of balanced incomplete block designs. Experimental results show that these general-purpose strategies can compete with, and in some cases outperform, previous more ad hoc procedures
A Model of Porous Catalyst Accounting for Incipiently Non-isothermal Effects

AbstractAn approximate model accounting for incipiently non-isothermal effects is derived from a well-known model of porous catalyst for appropriate, realistic limiting values of the parameters. In this limit, the original model is a singularly perturbed, m-D reaction–diffusion system, and the approximate model is given by the m-D heat equation with nonlinear boundary condition, coupled with infinitely many (ifm⩾2) 1-D semilinear parabolic equations, one for each point of the boundary of the spatial domain. Some limiting cases are still considered in the approximate model that lead to further simplifications
Characterization of a caldesmon fragment that competes with myosin-ATP binding to actin

The protein caldesmon inhibits actin-activated ATP hydrolysis of myosin and inhibits the binding of myosin.ATP to actin. A fragment isolated from a chymotryptic digest of caldesmon contains features of the intact molecule that make it useful as a selective inhibitor of the binding of myosin.ATP complexes to actin without having the complexity of binding to myosin. The COOH-terminal 20 kDa region of caldesmon binds to actin with one-sixth the affinity of caldesmon with a stoichiometry of binding of one fragment per two actin monomers. This contrasts with the 1:6–9 stoichiometry of intact caldesmon. The binding of the 20 kDa fragments to actin is totally reversed by Ca(2+)-calmodulin and, like intact caldesmon, the 20 kDa fragments are competitive with the binding of myosin subfragments to actin. This competition with myosin binding is largely responsible for the inhibition of ATP hydrolysis, although both the fragments and intact caldesmon also reverse the potentiation of ATPase activity caused by tropomyosin. These polypeptides are useful both in defining the function of caldesmon and in studying the role of weakly bound cross-bridges in muscle
Measurement of the e+e−→π+π− cross section between 600 and 900 MeV using initial state radiation

AbstractWe extract the e+e−→π+π− cross section in the energy range between 600 and 900 MeV, exploiting the method of initial state radiation. A data set with an integrated luminosity of 2.93 fb−1 taken at a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider is used. The cross section is measured with a systematic uncertainty of 0.9%. We extract the pion form factor |Fπ|2 as well as the contribution of the measured cross section to the leading-order hadronic vacuum polarization contribution to (g−2)μ. We find this value to be aμππ,LO(600–900MeV)=(368.2±2.5stat±3.3sys)⋅10−10, which is between the corresponding values using the BaBar or KLOE data
On the Domain of Convergence and Poles of ComplexJ-Fractions

AbstractConsider the infiniteJ-fraction [formula] wherean∈C\{0},bn∈C. Under very general conditions on the coefficients {an}, {bn}, we prove that this continued fraction converges to a meromorphic function in C\R. Such conditions hold, in particular, if limnJ(an)=limnJ(bn)=0 and ∑n⩾0(1/|an|)=∞ (or ∑n⩾0(|bn|/|anan+1|)=∞). The poles are located in the point spectrum of the associated tridiagonal infinite matrix and their order determined in terms of the asymptotic behavior of the zeros of the denominators of the corresponding partial fractions
The earth Mantle-Core effect in charge-asymmetries for atmospheric neutrino oscillations

AbstractEarth medium effects in the three-neutrino oscillations of atmospheric neutrinos are observable under appropriate conditions. This Letter generalizes the study of the medium effects and the possibility of their observation in the atmospheric neutrino oscillations from the case of neutrinos traversing only the Earth mantle, where the density is essentially constant, to the case of atmospheric neutrinos crossing also the Earth core. In the latter case new resonance-like effects become apparent. We calculate the CPT-odd asymmetry for the survival probability of muon neutrinos and the observable muon-charge asymmetry, taking into account the different atmospheric neutrino fluxes, and show the dependence of these asymmetries on the sign of Δm231 and on the magnitude of the mixing angle θ13. A magnetized detector with a sufficiently good neutrino momentum resolution is required for the observation of the muon-charge asymmetry generated by the Earth mantle-core effect
Fractional-chaotic inflation in the lights of PLANCK and BICEP2

AbstractIn the lights of current BICEP2 observations accompanied with the PLANCK satellite results, it has been observed that the simple single field chaotic inflationary models provide a good agreement with their spectral index ns and large tensor-to-scalar ratio r (0.15<r<0.26). To explore the other simple models, we consider the fractional-chaotic inflationary potentials of the form V0ϕa/b where a and b are relatively prime. We show that such kind of inflaton potentials can be realized elegantly in the supergravity framework with generalized shift symmetry and a nature bound a/b<4 for consistency. Especially, for the number of e-folding from 50 to 60 and some a/b from 2 to 3, our predictions are nicely within at least 1σ region in the (r–ns) plane. We also present a systematic investigation of such chaotic inflationary models with fractional exponents to explore the possibilities for the enhancement in the magnitude of running of spectral index (αns) beyond the simplistic models
Institutional change and innovation system transformation: A tale of two academies

AbstractThis paper investigates interactions between institutional adaptation and the transformation of science and innovation systems by analysing change and adjustment in post-socialist science academies. Two leading examples are examined: the Chinese Academy of Sciences (CAS) and the Russian Academy of Sciences (RAS). A heuristic framework of institutional change markers is applied to the analysis of nanotechnology research in both countries. We draw on bibliometric sources, interviews and secondary sources. We find that while the two Academies share a common past as the dominant research agents in their respective systems, their current positions and trajectories now differ. The nanotechnology case shows that CAS has adapted to China's modernisation, engaged in central government policy initiatives, and interacted with other research performers. CAS remains central to the Chinese research system, and has rejuvenated and expanded its resource base. RAS, on the contrary, has taken a protectionist stance: it still dominates the Russian research system and has a strong nanotechnology position, enforced by its gatekeeper control over journal publication. Nevertheless, RAS has faced difficulties in internal modernisation, leading to the external imposition of reforms and further role diminishment. The paper offers comparative insights into processes of institutional adaptation and highlights how key institutions can influence system transition
Tunes stuck in your brain: The frequency and affective evaluation of involuntary musical imagery correlate with cortical structure

AbstractRecent years have seen a growing interest in the neuroscience of spontaneous cognition. One form of such cognition is involuntary musical imagery (INMI), the non-pathological and everyday experience of having music in one’s head, in the absence of an external stimulus. In this study, aspects of INMI, including frequency and affective evaluation, were measured by self-report in 44 subjects and related to variation in brain structure in these individuals. Frequency of INMI was related to cortical thickness in regions of right frontal and temporal cortices as well as the anterior cingulate and left angular gyrus. Affective aspects of INMI, namely the extent to which subjects wished to suppress INMI or considered them helpful, were related to gray matter volume in right temporopolar and parahippocampal cortices respectively. These results provide the first evidence that INMI is a common internal experience recruiting brain networks involved in perception, emotions, memory and spontaneous thoughts
Rule induction performance in amnestic mild cognitive impairment and Alzheimer's dementia: Examining the role of simple and biconditional rule learning processes

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                  168462.pdf (publisher's version ) (Open Access)INTRODUCTION: Rule induction tests such as the Wisconsin Card Sorting Test require executive control processes, but also the learning and memorization of simple stimulus-response rules. In this study, we examined the contribution of diminished learning and memorization of simple rules to complex rule induction test performance in patients with amnestic mild cognitive impairment (aMCI) or Alzheimer's dementia (AD). METHOD: Twenty-six aMCI patients, 39 AD patients, and 32 control participants were included. A task was used in which the memory load and the complexity of the rules were independently manipulated. This task consisted of three conditions: a simple two-rule learning condition (Condition 1), a simple four-rule learning condition (inducing an increase in memory load, Condition 2), and a complex biconditional four-rule learning condition-inducing an increase in complexity and, hence, executive control load (Condition 3). RESULTS: Performance of AD patients declined disproportionately when the number of simple rules that had to be memorized increased (from Condition 1 to 2). An additional increment in complexity (from Condition 2 to 3) did not, however, disproportionately affect performance of the patients. Performance of the aMCI patients did not differ from that of the control participants. In the patient group, correlation analysis showed that memory performance correlated with Condition 1 performance, whereas executive task performance correlated with Condition 2 performance. CONCLUSIONS: These results indicate that the reduced learning and memorization of underlying task rules explains a significant part of the diminished complex rule induction performance commonly reported in AD, although results from the correlation analysis suggest involvement of executive control functions as well. Taken together, these findings suggest that care is needed when interpreting rule induction task performance in terms of executive function deficits in these patients.11 p
Impact of percutaneous coronary intervention timing on 5-year outcome in patients with non-ST-segment elevation acute coronary syndromes. The 'wait a day' approach might be safer

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                  172759.pdf (publisher's version ) (Open Access)BACKGROUND: The OPTIMA trial was a randomised multicentre trial exploring the influence of the timing of percutaneous coronary intervention (PCI) on patient outcomes in an intermediate to high risk non-ST-elevation acute coronary syndrome (NSTE-ACS) population. In order to decide the best treatment strategy for patients presenting with NSTE-ACS, long-term outcomes are essential. METHODS: Five-year follow-up data from 133 of the 142 patients could be retrieved (94 %). The primary endpoint was a composite of death and spontaneous myocardial infarction (MI). Spontaneous MI was defined as MI occurring more than 30 days after randomisation. Secondary endpoints were the individual outcomes of death, spontaneous MI or re-PCI. RESULTS: No significant difference with respect to the primary endpoint was observed (17.8 vs. 10.1 %; HR 1.55, 95 % CI: 0.73-4.22, p = 0.21). There was no significant difference in mortality rate. However, spontaneous MI was significantly more common in the group receiving immediate PCI (11.0 vs. 1.4 %; HR 4.46, 95 % CI: 1.21-16.50, p = 0.02). We did not find a significant difference between the groups with respect to re-PCI rate. CONCLUSION: There was no difference in the composite of death and spontaneous MI. The trial suggests an increased long-term risk of spontaneous MI for patients treated with immediate PCI
Search for supersymmetry in electroweak production with photons and large missing transverse energy in pp collisions at sqrt(s) = 8 TeV

Results are reported from a search for supersymmetry with gauge-mediated supersymmetry breaking in electroweak production. Final states with photons and large missing transverse energy ( View the MathML sourceETmiss) were examined. The data sample was collected in pp collisions at View the MathML sources=8TeV with the CMS detector at the LHC and corresponds to 7.4View the MathML sourcefb−1. The analysis focuses on scenarios in which the lightest neutralino has bino- or wino-like components, resulting in decays to photons and gravitinos, where the gravitinos escape undetected. The data were obtained using a specially designed trigger with dedicated low thresholds, providing good sensitivity to signatures with photons, View the MathML sourceETmiss, and low hadronic energy. No excess of events over the standard model expectation is observed. The results are interpreted using the model of general gauge mediation. With the wino mass fixed at 10View the MathML sourceGeV above that of the bino, wino masses below 710View the MathML sourceGeV are excluded at 95% confidence level. Constraints are also set in the context of two simplified models, for which the analysis sets the lowest cross section limits on the electroweak production of supersymmetric particles
First year design "Visualisation II": The hybridisation of analogue and digital tools

This paper discusses first year students’ responses and outcomes to the integration of digital technologies in their second semester foundational visualisation class; ‘Visualisation II’. As the second class in the Visualisation series, previous analogue knowledge taught in ‘Visualisation I’ is compounded with new digital technologies establishing the introduction to a myriad of hybrid visualisation tools and techniques for design exploration and design artefact. This research examines the differentiation between analogue and digital design, common precedents of the two, and reflects upon the environment and class structure with the learning experiences and confidence of surveyed participants
Search for physics beyond the standard model using multilepton signatures in pp collisions at √s =7 TeV

A search for physics beyond the standard model in events with at least three leptons and any number of jets is presented. The data sample corresponds to 35 inverse picobarns of integrated luminosity in pp collisions at sqrt(s) = 7 TeV collected by the CMS experiment at the LHC. A number of exclusive multileptonic channels are investigated and standard model backgrounds are suppressed by requiring sufficient missing transverse energy, invariant mass inconsistent with that of the Z boson, or high jet activity. Control samples in data are used to ascertain the robustness of background evaluation techniques and to minimise the reliance on simulation. The observations are consistent with background expectations. These results constrain previously unexplored regions of supersymmetric parameter space
See you on Facebook: the effect of social networking on human interaction

This paper proposes an evolutionary framework to explore the dynamics of social interaction in an environment characterized by online networking and increasing pressure on time. The model shows how time pressure encourages the choice to develop social interactions also through online networking instead of relying exclusively on face to face encounters.
Our findings suggest that the joint influence exerted by the reduction in leisure time and the new opportunities of participation offered by web-mediated communication may progressively lead a growing share of the population to adopt networking sites as an indispensable environment for the development of interpersonal relationships.
Does unemployment insurance crowd out home production?

In this paper, we study the interaction between self insurance and public insurance. In particular, we provide evidence on the relationship between unemployment insurance beneﬁts and home production using the American Time Use Survey (ATUS) and the state-level unemployment insurance data of the U.S. The empirical results suggest that moving to a two times more generous state would decrease time spent on home production about 20% for unemployed. Then we pursue a quantitative assessment using a dynamic competitive  equilibrium model in which households do home production as well as market production. The model is able to generate the empirical facts regarding unemployment beneﬁts and home
production. The fact that unemployment insurance beneﬁts crowd out home production is interpreted as a substitution between the two insurance mechanisms against loss of earnings during unemployment spells.
Estimating a monetary policy rule for India

This paper investigates whether the seemingly discretionary and flexible approach of the Reserve Bank of India can in practice be described by a Taylor-type rule. It estimates an exchange-rate-augmented Taylor rule for India over the period Quarter 1 of 1980 to Quarter 4 of 2008. It investigates monetary policy changes between the pre- and post-liberalization periods in order to capture the potential impact of macroeconomic structural changes on the RBI's monetary policy conduct. Overall, it finds that the output gap seems to matter more to RBI than inflation, there is greater sensitivity to consumer price inflation, exchange rate changes do not constitute an important policy factor, and the post-1998 conduct of monetary policy seems to have changed in the direction of
less inertia.
Quantitative mu-calculus and CTL Based on Constraint Semirings

Model checking and temporal logics are boolean. The answer to the model checking question does a system satisfy a property? is either true or false, and properties expressed in temporal logics are defined over boolean propositions. While this classic approach is enough to specify and verify boolean temporal properties, it does not allow to reason about quantitative aspects of systems. Some quantitative extensions of temporal logics has been already proposed, especially in the context of probabilistic systems. They allow to answer questions like with which probability does a system satisfy a property?\ud
We present a generalization of two well-known temporal logics: CTL and the [mu]-calculus. Both extensions are defined over c-semirings, an algebraic structure that captures many problems and that has been proposed as a general framework for soft constraint satisfaction problems (CSP). Basically, a c-semiring consists of a domain, an additive operation and a multiplicative operation, which satisfy some properties. We present the semantics of the extended logics over transition systems, where a formula is interpreted as a mapping from the set of states to the domain of the c-semiring, and show that the usual connection between CTL and [mu]-calculus does not hold in general. In addition, we reason about the feasibility of computing the logics and illustrate some applications of our framework, including boolean model checking