pinecone/core-2020-05-10-deduplication huggingface dataset:
Centrality dependence of (sic)(2S) suppression in p-Pb collisions at root s(NN)=5.02 TeV

The inclusive production of the (sic)(2S) charmonium state was studied as a function of centrality in p-Pb collisions at the nucleon- nucleon center of mass energy root s(NN) = 5.02TeV at the CERN LHC. The measurement was performed with the ALICE detector in the center of mass rapidity ranges -4.46 &lt; y(cms) &lt; -2.96 and 2.03 &lt; y(cms) &lt; 3.53, down to zero transverse momentum, by reconstructing the (sic)(2S) decay to a muon pair. The (sic)(2S) production cross section sigma(sic)(2S) is presented as a function of the collision centrality, which is estimated through the energy deposited in forward rapidity calorimeters. The relative strength of nuclear effects on the (sic)(2S) and on the corresponding 1S charmonium state J/(sic) then studied by means of the double ratio of cross sections [sigma(sic)(2S)/sigma (J)/(sic)] (p)Pb/[sigma(sic)(2S)/sigma(J)/(sic)](pp) between p-Pb and pp collisions, and by the values of the nuclear modification factors for the two charmonium states. The results show a large suppression of (sic)(2S) production relative to the J/(sic) backward (negative) rapidity, corresponding to the light direction of the Pb-nucleus, while at forward (positive) rapidity the suppressions of the two states are comparable. Finally, comparisons to results from lower energy experiments and to available theoretical models are presented
Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells.

Contains fulltext :
                  108052.pdf (publisher's version ) (Open Access)Successful use of stem cell-based therapeutic products is conditioned by transplantation of optimized cells in permissive microenvironment. Mesenchymal stem cell (MSC) fates are tightly regulated by humoral factors, cellular interactions and extracellular matrix (ECM) components, such as glycosaminoglycans (GAG), which are complex polysaccharides with structural heterogeneity. During osteogenesis, a temporally controlled expression of particular GAG species is required to interact with specific growth promoting and differentiating factors to regulate their biological activities. As a comparative tool to study natural GAG, we used structurally and functionally related synthetic GAG mimetics. One of these compounds [OTR(4120)] was previously shown to stimulate bone repair in rat models. Here, we demonstrate that structurally distinct GAG mimetics stimulate differentially clonogenicity, proliferation, migration and osteogenic phenotype of MSC in vitro, according to their specific chemical signature, underlying the role of sulfate and acetyl groups in specific interactions with heparin binding factors (HBF). These effects are dependent on FGF-2 interactions since they are inhibited by a FGF receptor 1 signaling pathway blocker. These data suggest that the in vivo [OTR(4120)] bone regenerative effect could be due to its ability to induce MSC migration and osteogenic differentiation. To conclude, we provide evidences showing that GAG mimetics may have great interest for bone regeneration therapy and represent an alternative to exogenous growth factor treatments to optimize potential therapeutic properties of MSC.1 maart 201
Exploring the thread-level parallelisms for the next generation geophysical fluid modelling framework Fluidity-ICOM.

In this paper, we highlight our progress in implementing a hybrid OpenMP-MPI version of the unstructured finite element appli- cation Fluidity-ICOM. We demonstrate that utilising non-blocking algorithms and libraries are critical to mixed-mode application so that it can achieve better parallel performance than the pure MPI version. In the matrix assembly kernels, the OpenMP parallel algorithm utilises graph colouring to identify independent sets of elements that can be assembled simultaneously with no race con- ditions. The TCMalloc are used here to tackle performance issues arising from automatic arrays memory allocations. The sparse linear systems defined by various equations are solved by using threaded PETSc and HYPRE is utilised as a threaded preconditioner through the PETSc interface. Since unstructured finite element codes are well known to be memory bound, particular attention has to be paid to ccNUMA architectures where data locality is particularly important to achieve good intra-node scaling characteristics. With mixed mode MPI/OpenMP, Fluidity-ICOM can now run well above 32K cores job, which offers Fluidity-ICOM capability to solve the “grand-challenge” problems
Past 140-year environmental record in the northern South China Sea: Evidence from coral skeletal trace metal variations

About 140-year changes in the trace metals in Porites coral samples from two locations in the northern South China Sea were investigated. Results of PCA analyses suggest that near the coast, terrestrial input impacted behavior of trace metals by 28.4%, impact of Sea Surface Temperature (SST) was 19.0%, contribution of war and infrastructure were 14.4% and 15.6% respectively. But for a location in the open sea, contribution of War and SST reached 33.2% and 16.5%, while activities of infrastructure and guano exploration reached 13.2% and 14.7%. While the spatiotemporal change model of Cu, Cd and Pb in seawater of the north area of South China Sea during 1986-1997 were reconstructed. It was found that in the sea area Cu and Cd contaminations were distributed near the coast while areas around Sanya, Hainan had high Pb levels because of the well-developed tourism related activities. (C) 2013 Elsevier Ltd. All rights reserved
Approximate eigensolutions of the attractive potential via\ud
parametric Nikiforov-Uvarov method

The approximate analytical solutions of the non-relativistic Schrӧdinger equation for the Attractive potential model with the centrifugal term are investigated using the elegant methodology of the parametric Nikiforov-Uvarov. The energy equation and the corresponding un-normalized radial wave functions are obtained in a close and compact form after a proper Greene-Aldrich approximation scheme is applied. By changing the numerical values of some potential strengths, special cases of the Attractive potential are investigated in detail. The effects of the potential strengths and potential range respectively on the energy are also studied. The energy is found to be very sensitive to each of the potential parameters. Some theoretic quantities such as information energy, Rẻnyi entropy and Tsallis entropy
A secondary RET mutation in the activation loop conferring resistance to\ud
vandetanib

Resistance to vandetanib, a type I RET kinase inhibitor, developed in a\ud
patient with metastatic lung adenocarcinoma harboring a CCDC6-RET fusion\ud
that initially exhibited a response to treatment. The resistant tumor acquired\ud
a secondary mutation resulting in a serine-to-phenylalanine substitution at\ud
codon 904 in the activation loop of the RET kinase domain. The S904F\ud
mutation confers resistance to vandetanib by increasing the ATP affinity and\ud
autophosphorylation activity of RET kinase. A reduced interaction with drug\ud
is also observed in vitro for the S904F mutant by thermal shift assay. A crystal\ud
structure of the S904F mutant reveals a small hydrophobic core around F904\ud
likely to enhance basal kinase activity by stabilizing an active conformer.\ud
Our findings indicate that missense mutations in the activation loop of the\ud
kinase domain are able to increase kinase activity and confer drug resistance\ud
through allosteric effects
Determination of the top-quark pole mass and strong coupling constant from the ttbar production cross section in pp collisions at sqrt(s) = 7 TeV

The inclusive cross section for top-quark pair production measured by the CMS experiment in proton-proton collisions at a center-of-mass energy of 7 TeV is compared to the QCD prediction at next-to-next-to-leading order with various parton distribution functions to determine the top-quark pole mass, mtpole, or the strong coupling constant, alphaS. With the parton distribution function set NNPDF2.3, a pole mass of 176.7 +3.8 -3.4 GeV is obtained when constraining alphaS at the scale of the Z boson mass, mZ, to the current world average. Alternatively, by constraining mtpole to the latest average from direct mass measurements, a value of alphaS(mZ) = 0.1151 +0.0033 -0.0032 is extracted. This is the first determination of alphaS using events from top-quark production
Iron oxyhydroxide and sulphide mineralization in hydrocarbon seep-related\ud
carbonate submarine chimneys, Gulf of Cadiz (SW Iberian Peninsula)

This paper aims to investigate the iron mineralization hosted in the submarine hydrocarbon seep-related\ud
carbonate chimneys, from the Gulf of Cadiz continental slope (SW Iberia). Chimneys are made of\ud
a general fine groundmass of major Fe-rich dolomite, ankerite and calcite, small grains of quartz and\ud
phyllosilicates, and some foraminifer tests and ostracod shells. Primary porosity is frequently generated\ud
inside foraminifer chambers and ostracod shells, and is filled with closely packed microcrystals of iron\ud
oxyhydroxide and sulphide minerals forming framboids. Some extremely peculiar multiframboidal\ud
textures are also detected, corresponding to microcrystal groups, spherical framboids and euhedral\ud
crystals without framboidal texture. The mineralogy observed is mainly goethite (pyrite pseudomorphs);\ud
traces of tiny grains of pyrite were also observed. Cubic, octahedral and pyritohedral are the habits\ud
observed in both minerals. Chemical analyses of framboids and euhedral crystals display high (often\ud
erratic) amounts of As, Co, Ni and Mo in oxyhydroxides and Mo, Pb, V and Co in sulphides versus almost\ud
always negligible concentrations of Cu and Zn. A textural, geochemical and mineralogical evolution is\ud
proposed to explain the coexistence of different morphologies in the multiframboidal texture: (a) growth\ud
and aggregation of microcrystals as typical framboidal-type mineralogical associations; (b) development\ud
of euhedral habits; (c) coalescence and homogenization of the microcrystal into large size (euhedral to\ud
anhedral) crystals, and (d) formation of euhedral crystals or polycrystalline masses, with complete loss of\ud
framboidal texture. Along this process, an increase of the concentration of Fe, S, Mn and Ti, linked to\ud
a decrease in Mg, Si, Al, As, P, Ca and V was observed. The study of the iron mineralization in the Gulf of\ud
Cadiz is a first, and can give clues to understand the complex geobiological interactions in this and other\ud
similar extreme hydrocarbon-bearing submarine ecosystems
A photometric and spectroscopic study of the new dwarf spheroidal galaxy
  in Hercules

Our aim is to provide as clean and as complete a sample as possible of red
giant branch stars that are members of the Hercules dSph galaxy. With this
sample we explore the velocity dispersion and the metallicity of the system.
Stromgren photometry and multi-fibre spectroscopy are combined to provide
information about the evolutionary state of the stars (via the Stromgren c_1
index) and their radial velocities. Based on this information we have selected
a clean sample of red giant branch stars, and show that foreground
contamination by Milky Way dwarf stars can greatly distort the results. Our
final sample consists of 28 red giant branch stars in the Hercules dSph galaxy.
Based on these stars we find a mean photometric metallicity of -2.35 dex which
is consistent with previous studies. We find evidence for an abundance spread.
Using those stars for which we have determined radial velocities we find a
systemic velocity of 45.2 km/s with a dispersion of 3.72 km/s, this is lower
than values found in the literature. Furthermore we identify the horizontal
branch and estimate the mean magnitude of the horizontal branch of the Hercules
dSph galaxy to be V_0=21.17, which corresponds to a distance of 147 kpc. We
have shown that a proper cleaning of the sample results in a smaller value for
the velocity dispersion of the system. This has implications for galaxy
properties derived from such velocity dispersions.Comment: 24 pages, 28 figure
Measurement of the energy spectrum of cosmic rays above 10^18 eV using
  the Pierre Auger Observatory

We report a measurement of the flux of cosmic rays with unprecedented
precision and statistics using the Pierre Auger Observatory. Based on
fluorescence observations in coincidence with at least one surface detector we
derive a spectrum for energies above 10^18 eV. We also update the previously
published energy spectrum obtained with the surface detector array. The two
spectra are combined addressing the systematic uncertainties and, in
particular, the influence of the energy resolution on the spectral shape. The
spectrum can be described by a broken power law E^-gamma with index gamma=3.3
below the ankle which is measured at log10(E/eV) = 18.6. Above the ankle the
spectrum is described by a power law with index 2.6 followed by a flux
suppression, above about log10(E/eV) = 19.5, detected with high statistical
significance.Comment: Accepted for publication in Physics Letters
Tensor factorizations of local second-order M{\o}ller Plesset theory

Efficient electronic structure methods can be built around efficient tensor
representations of the wavefunction. Here we describe a general view of tensor
factorization for the compact representation of electronic wavefunctions. We
use these ideas to construct low-complexity representations of the doubles
amplitudes in local second order M{\o}ller-Plesset perturbation theory. We
introduce two approximations - the direct orbital specific virtual
approximation and the full orbital specific virtual approximation. In these
approximations, each occupied orbital is associated with a small set of
correlating virtual orbitals. Conceptually, the representation lies between the
projected atomic orbital representation in Pulay-Saeb{\o} local correlation
theories and pair natural orbital correlation theories. We have tested the
orbital specific virtual approximations on a variety of systems and properties
including total energies, reaction energies, and potential energy curves.
Compared to the Pulay-Saeb{\o} ansatz, we find that these approximations
exhibit favourable accuracy and computational times, while yielding smooth
potential energy curves
Strong annihilating pairs for the Fourier-Bessel transform

The aim of this paper is to prove two new uncertainty principles for the
Fourier-Bessel transform (or Hankel transform). The first of these results is
an extension of a result of Amrein-Berthier-Benedicks, it states that a non
zero function $f$ and its Fourier-Bessel transform $\mathcal{F}_\alpha (f)$
cannot both have support of finite measure. The second result states that the
supports of $f$ and $\mathcal{F}_\alpha (f)$ cannot both be
$(\eps,\alpha)$-thin, this extending a result of Shubin-Vakilian-Wolff. As a
side result we prove that the dilation of a $\cc_0$-function are linearly
independent. We also extend Faris's local uncertainty principle to the
Fourier-Bessel transform.Comment: 19p
Antisymmetric tensor fields in a generalized Randall-Sundrum scenario

Bulk antisymmetric tensor fields of different ranks have been studied in the
context of a generalized Randall-Sundrum model with a non-vanishing induced
cosmological constant on the visible brane. It is shown that instead of the
usual exponential suppression of the couplings of the zero modes of these bulk
fields with the brane fermions in the original Randal-Sundrum model, here the
couplings are proportional to the brane cosmological constant. Thus in an era
of large cosmological constant these fields have significant role in physical
phenomena because of their enhanced couplings with the visible brane fermions.Comment: 14 Pages, 1 figure, Revte
Search for Spatial Structures at Scales Z~1. III. The Effect of Lensing
  on QSO ?

We carried out a search for peak inhomogeneities in the distribution of
matter - namely clumps and voids, within the range Z ~ 1-3. We used a new
method, based on the lensing of quasars by a combination of lenses, belonging
to the above sought inhomogeneities in the matter distribution. This work
confirms the evidence of the existence of inhomogeneities found by us earlier -
of a clump (superattractor N.1), and of a void (supervoid). Besides, the
existence of a new gigantic clump (superattractor N.2) was also discovered at Z
~ 3. These clumps could well serve as centers of the Bose-condensation in the
early Universe; in particular - as Anselm's arion condensate, which leads to
the formation of quasiperiodic structures with a period p ~ 100-200 Mpc.Comment: 22 pages, 2 figures, 6 tables. submitted to Astrophys.& Space Sc
Magnetic flux penetration and motion in antiferromagnetic
  superconductors

The paper reviews a concept of induced spin-flop domain inside vortices in an
antiferromagnetic superconductor. Such phenomenon may occur when an external
magnetic field is strong enough to flip over magnetic moments in the core of
the vortex from their ground state configuration. The formation of the domain
structure inside vortices modifies the surface energy barrier of the
superconductor. During this process the entrance of the flux is stopped and a
newly created state exhibits perfect shielding. Such behavior should be visible
as a plateau on the dependence of flux density as a function of the external
magnetic field. The end of the plateau determines the critical field, which has
been called the second critical field for flux penetration. Moreover, it is
predicted and described how this phenomenon modifies flux creep in layered
superconductors. The various scenarios of changing the creep regime from
thermal to quantum and vice versa at constant temperature are discussed.Comment: Invited talk presented at NATO ARW: Vortex dynamics in HTSC, Tashkent
  17-22 May, 2002, Uzbekista
Toward a Theory of Orbiton Dispersion in LaMnO_3

At 750K, LaMnO_3 has a cooperative Jahn-Teller (JT) distortion, with Mn atoms
in distorted oxygen octahedra. This lifts the degeneracy of the singly-occupied
$e_g$ orbitals of the Mn$^{3+}$ ions, which then become orbitally ordered. We
use a minimal model to describe the ordered phase at T=0. The on-site Coulomb
repulsion $U$ is set to infinity. There are two electronic orbitals and three
oxygen vibrational coordinates per unit cell. In addition to spin excitations
and phonons, the model has electronic excitations consisting of mis-orienting
orbitals on Mn ions. Neglecting coupling to the oxygen displacements, the gap
to such excitations is $2\Delta=16g^2/K$ where $g$ is the electron-phonon
coupling and $K$ is the oxygen spring constant. When static oxygen
displacements are coupled, this excitation becomes a self-trapped exciton with
energy $\Delta$, half the JT gap. Adding dynamic oxygen displacements in
one-phonon approximation introduces dispersion to both the (previously
Einstein-like) phonons and the orbital excitons (``orbitons''). One of the
phonon branches has zero frequency at $\vec{k}=(0,0,\pi)$. This is the
Goldstone mode of the JT broken symmetry.Comment: 8 pages with 3 figures included. Submitted to the International
  Conference on Solid State Spectroscopy (conference in September 1999 to honor
  Manuel Cardona), Physica Status Solidi (b) (September 1999
Geometric classification of the torsion tensor in space-time

Torsion appears in literature in quite different forms. Generally, spin is
considered to be the source of torsion, but there are several other
possibilities in which torsion emerges in different contexts. In some cases a
phenomenological counterpart is absent, in some other cases torsion arises from
sources without spin as a gradient of a scalar field. Accordingly, we propose
two classification schemes. The first one is based on the possibility to
construct torsion tensors from the product of a covariant bivector and a vector
and their respective space-time properties. The second one is obtained by
starting from the decomposition of torsion into three irreducible pieces. Their
space-time properties again lead to a complete classification. The
classifications found are given in a U_4, a four dimensional space-time where
the torsion tensors have some peculiar properties. The irreducible
decomposition is useful since most of the phenomenological work done for
torsion concerns four dimensional cosmological models. In the second part of
the paper two applications of these classification schemes are given. The
modifications of energy-momentum tensors are considered that arise due to
different sources of torsion. Furthermore, we analyze the contributions of
torsion to shear, vorticity, expansion and acceleration. Finally the
generalized Raychaudhuri equation is discussed.Comment: LATEX file, 18 pages, accepted for Publication in Annalen der Physi
Measurement of the W-Pair Production Cross Section and W-Decay Branching
  Fractions in e+e- Interactions at sqrt{s}=189GeV

The data collected by the L3 experiment at LEP at a centre-of-mass energy of
188.6 GeV are used to measure the W-pair production cross section and the
W-boson decay branching fractions. These data correspond to an integrated
luminosity of 176.8pb^-1. The total cross section for W-pair production,
combining all final states, is measured to be sigma_WW = 16.24 +/- 0.37(stat.)
+/- 0.22(syst.) pb. Including our data collected at lower centre-of-mass
energies, the hadronic branching fraction of the W-boson is determined to be
B(W ->qq) = [68.20 +/- 0.68 (stat.) +/- 0.33 (syst.) ] %. The results agree
with the Standard Model predictions
Gauge invariant Z_2 vortex vacuum textures and the SU(2) gluon
  condensate

For SU(2) lattice gauge theory, a new SO(3) cooling procedure is proposed
which removes the SU(2)/Z(2) coset fields from the lattice configurations and
reveals a Z(2) vortex vacuum texture different from the P-vortex content
obtained in the maximal center gauge. Cooling can be restricted in a
renormalization group invariant way by a parameter controlling the remaining
SO(3) action density. A gauge invariant Z(2) vortex vacuum emerges
asymptotically if cooling is not restricted. This ``vortex texture'' does not
support the string tension or a finite part of it. The SU(2) action density
associated with the new Z(2) vortex texture has a smooth extrapolation to the
continuum limit. We propose an interpretation as a mass dimension four
condensate related to the gluon condensate featuring in the operator product
expansion.Comment: 26 pages, 8 figures, completely revised versio
Intrinsic Magnetism in Nanosheets of SnO$_{2}$: A First-principles Study

We propose intrinsic magnetism in nanosheets of SnO$_{2}$, based on
first-principles calculations. The electronic structure and spin density reveal
that $p$ orbitals of the oxygen atoms, surrounding Sn vacancies, have a non
itinerant nature which gives birth to localized magnetism. A giant decrease in
defect formation energies of Sn vacancies in nanosheets is observed. We,
therefore, believe that native defects can be stabilized without any chemical
doping. Nanosheets of different thicknesses are also studied, and it is found
that it is easier to create vacancies, which are magnetic, at the surface of
the sheets. SnO$_{2}$ nanosheets can, therefore, open new opportunities in the
field of spintronics.Comment: J. Magn. Magn. Mate. 2012 (Accepted