pinecone/core-2020-05-10-deduplication huggingface dataset:
Indices of Metabolic Dysfunction and Oxidative Stress

Abstract  Metabolic alterations are a key player involved in the onset of Alzheimer disease pathophysiology and, in this review, we focus on diet, metabolic rate, and neuronal size differences that have all been shown to play etiological and pathological roles in Alzheimer disease. Specifically, one of the earliest manifestations of brain metabolic depression in these patients is a sustained high caloric intake meaning that general diet is an important factor to take in account. Moreover, atrophy in the vasculature and a reduced glucose transporter activity for the vessels is also a common feature in Alzheimer disease. Finally, the overall size of neurons is larger in cases of Alzheimer disease than that of age-matched controls and, in individuals with Alzheimer disease, neuronal size inversely correlates with disease duration and positively associates with oxidative stress. Overall, clarifying cellular and molecular manifestations involved in metabolic alterations may contribute to a better understanding of early Alzheimer disease pathophysiology.http://dx.doi.org/10.1007/s11064-007-9296-
Planck 2013 results. VII. HFI time response and beams

This paper characterizes the effective beams, the effective beam window functions and the associated errors for the Planck High Frequency Instrument (HFI) detectors. The effective beam is theangular response including the effect of the optics, detectors, data processing and the scan strategy. The window function is the representation of this beam in the harmonic domain which is required to recover an unbiased measurement of the cosmic microwave background angular power spectrum. The HFI is a scanning instrument and its effective beams are the convolution of: a) the optical response of the telescope and feeds; b) the processing of the time-ordered data and deconvolution of the bolometric and electronic transfer function; and c) the merging of several surveys to produce maps. The time response transfer functions are measured using observations of Jupiter and Saturn and by minimizing survey difference residuals. The scanning beam is the post-deconvolution angular response of the instrument, and is characterized with observations of Mars. The main beam solid angles are determined to better than 0.5% at each HFI frequency band. Observations of Jupiter and Saturn limit near sidelobes (within 5°) to about 0.1% of the total solid angle. Time response residuals remain as long tails in the scanning beams, but contribute less than 0.1% of the total solid angle. The bias and uncertainty in the beam products are estimated using ensembles of simulated planet observations that include the impact of instrumental noise and known systematic effects. The correlation structure of these ensembles is well-described by five error eigenmodes that are sub-dominant to sample variance and instrumental noise in the harmonic domain. A suite of consistency tests provide confidence that the error model represents a sufficient description of the data. The total error in the effective beam window functions is below 1% at 100 GHz up to multipole â.," ~ 1500, and below 0.5% at 143 and 217 GHz up to ~ 2000. © 2014 ESO
Electroluminescence efficiency of blue InGaN/GaN quantum-well diodes with and without an n-InGaN electron reservoir layer

The temperature dependence of the electroluminescence (EL) spectral intensity has been investigated in detail between T=20 and 300  K at various injection current levels for a set of two blue InGaN/GaN multiple-quantum-well (MQW) light-emitting diodes (LEDs) with and without an additional n-doped In0.18Ga0.82N electron reservoir layer (ERL). The radiative recombination efficiency of the main blue emission band (~480  nm) is found to be significantly improved at all temperature regions and current levels when the additional ERL is introduced. For high injection currents If, i.e., large forward bias voltages Vf, a quenching of the EL intensity is observed for T<100  K for both LED structures, accompanying appearance of short-wavelength satellite emissions around 380–430  nm. Furthermore, the low-temperature intensity reduction of the main EL band is stronger for the LED without the ERL than with the ERL. For low If, i.e., small Vf, however, no quenching of the EL intensity is observed for both LEDs even below 100  K and the short-wavelength satellite emissions are significantly reduced. These results of the main blue emission and the short-wavelength satellite bands imply that the unusual evolution of the EL intensity with temperature and current is caused by variations of the actual potential field distribution due to both internal and external fields. They significantly influence the carrier capture efficiency by radiative recombination centers within the active MQW layer and the carrier escape out of the active regions into high-energy recombination centers responsible for the short-wavelength satellite emissions
An experiment for two-color photoionization using high intensity extreme-UV free electron and near-IR laser pulses

We describe an experimental system designed for single-shot photoelectron spectroscopy on free atoms and molecules at the Free Electron Laser in Hamburg (FLASH at DESY). The combination of the extreme ultra-violet (EUV) Free Electron Laser and a temporally synchronized optical fs laser (Ti:Sapphire) enables a variety of two-color pump-probe experiments. The spectral, temporal and spatial characteristics of both the EUV FEL and the optical laser pulses, the experimental procedure to control their overlap as well as the performance of an electron spectrometer used to obtain single-shot photoelectron spectra are discussed. As an illustration of the capabilities of this set-up, some results on two-photon two-color ionization of rare gases are presented
Degradation and breakdown characteristics of thin MgO dielectric layers

MgO has been suggested as a possible high-k dielectric for future complementary metal-oxide semiconductor processes. In this work, the time dependent dielectric breakdown (TDDB) characteristics of 20 nm MgO films are discussed. Stress induced leakage current measurements indicate that the low measured Weibull slopes of the TDDB distributions for both n-type and p-type devices cannot be attributed to a lower trap generation rate than for SiO2. This suggests that much fewer defects are required to trigger breakdown in MgO under voltage stress than is the case for SiO2 or other metal-oxide dielectrics. This in turn explains the progressive nature of the breakdown in these films which is observed both in this work and elsewhere. The reason fewer defects are required is attributed to the morphology of the films
Dublin City University at CLEF 2006: Experiments for the ImageCLEF Photo Collection Standard Ad Hoc Task

We provide a technical description of our submission to the CLEF 2006 Cross Language Image Retrieval(ImageCLEF) Photo Collection Standard Ad Hoc task. We performed monolingual and cross language retrieval of photo images using photo annotations with and without feedback, and also a combined visual and text retrieval approach. Topics are translated into English using the Babelfish online machine translation\ud
system. Our text runs used the BM25 algorithm, while our visual approach used simple low-level features with matching based on the Jeffrey Divergence measure. Our results consistently indicate that the fusion of text and visual features is best for this task, and that performing feedback for text consistently improves on the baseline\ud
non-feedback BM25 text runs for all language pairs
A triangle model of criminality

This paper is concerned with a quantitative model describing the interaction of three sociological species, termed as owners, criminals and security guards, and denoted by X, Y and Z respectively. In our model, Y is a predator of the species X, and so is Z with respect to Y . Moreover, Z can also be thought of as a predator of X, since this last population is required to bear the costs of maintaining Z. We propose a system of three ordinary differential equations to account for the time evolution of X(t), Y (t) and Z(t) according to our previous assumptions. Out of the various parameters that appear in that system, we select two of them, denoted by H, and h, which are related with the efficiency of the security forces as a control parameter in our discussion. To begin with, we consider the case of large and constant owners population, which allows us to reduce (3)–(5) to a bidimensional system for Y (t) and Z(t). As a preliminary step, this situation is first discussed under the additional assumption that Y (t) + Z(t) is constant. A bifurcation study is then performed in terms of H and h, which shows the key role played by the rate of casualties in Y and Z, that results particularly in a possible onset of bistability. When the previous restriction is dropped, we observe the appearance of oscillatory behaviours in the full two-dimensional system. We finally provide a exploratory study of the complete model (3)–(5), where a number of bifurcations appear as parameter H changes, and the corresponding solutions behaviours are described
Cost-effectiveness of groundwater conservation measures: A multi-level analysis with policy implications

Groundwater in Spain, as in other arid and semiarid countries worldwide, has been widely used in the expansion of irrigated agriculture. In the Spanish Mancha Occidental aquifer, the excessive, and sometimes illegal, water abstraction for irrigation has promoted outstanding socioeconomic development in the area, but it has also resulted in exploitation of the aquifer and degradation of valuable wetlands. Water policies implemented in the region have not yet managed to restore the aquifer and face strong social opposition. This paper uses a multi-scale modeling approach to explore the environmental and socio-economic impacts of alternative water conservation measures at the farm and basin levels. It also analyzes their comparative cost-effectiveness to help policy makers identify the least costly policy option for achieving the goal of the Mancha Occidental aquifer's sustainability. To conduct this analysis, a Mathematical Programming Model has been developed to simulate: the closing-up and taxed-legalization of unlicensed wells, uniform volumetric and block-rate water prices, water quotas, and water markets. Aggregate results show that net social costs are not substantially different across policy option, so none of the considered policy options will be clearly more cost-effective than the others. However, there are significant differences between private and public costs (at the farm and sub-basin levels), which will be critical for determining the application in practice of these policies. Results show that controlling illegal water mining (through the legalization of unlicensed wells) is necessary, but is not sufficient to recover the aquifer. Rather, effective water management in this area will require the implementation of other water management policies as well. Among them, uniform volumetric and block-rate water pricing policies will entail the lowest net social cost, but will produce important income losses in the smallest and most water-intensive farms, which might put at risk the viability of these farms and the social acceptance of the policies. Further investigations on social costs, policy enforcement capacity and public participation in water management are highly recommende
A process for managing interaction between experimenters to get useful similar replications

Context: A replication is the repetition of an experiment. Several efforts have been made to adopt replication as a common practice in software engineering. There are different types of replications, depending on their purpose. Similar replications keep the experimental conditions as alike as possible to the original ones. External similar replications, where the replicating experimenters are not the same people as the original experimenters, have been a stumbling block. Several attempts at combining the results of replications have resulted in failure. Software engineering does not appear to be well suited to such replications, because it works with complex experimentally immature contexts. Software engineering settings have a large number of variables, and the role that many of them play is unknown. A successful (or useful) similar replication helps to better understand the phenomenon under study by verifying results and/or identifying contextual variables that could influence (or not) the results, through the combination of experimental results. Objective: To be able to get successful similar replications, there needs to be interaction between original and replicating experimenters. In this paper, we propose an interaction process for achieving successful similar replications. Method: This process consists of: an adaptation meeting, where experimenters tailor the experiment to the new setting; querying, to settle occasional inquiries while the experiment is being run; and a combination meeting, where experimenters meet to discuss the combination of replication outcomes with previous results. To check its effectiveness, the process has been tested on three different replications of the same experiment. Results: The proposed interaction process has helped to identify new contextual variables that could potentially influence (or not) the experimental results in the three replications run. Additionally, the interaction process has helped to uncover certain problems and deviations that occurred during some of the replications that we would have not been aware of otherwise. Conclusions: There are signs that suggest that it is possible to get successful similar replications in soft- ware engineering experimentation, when there is appropriate interaction among experimenters
Experimental verification of intermediate band formation on titanium-implanted silicon

Intermediate band formation on silicon layers for solar cell applications was achieved by titanium implantation and laser annealing. A two-layer heterogeneous system, formed by the implanted layer and by the un-implanted substrate, was formed. In this work, we present for the first time electrical characterization results which show that recombination is suppressed when the Ti concentration is high enough to overcome the Mott limit, in agreement with the intermediate band theory. Clear differences have been observed between samples implanted with doses under or over the Mott limit. Samples implanted under the Mott limit have capacitance values much lower than the un-implanted ones as corresponds to a highly doped semiconductor Schottky junction. However, when the Mott limit is surpassed, the samples have much higher capacitance, revealing that the intermediate band is formed. The capacitance increasing is due to the big amount of charge trapped at the intermediate band, even at low temperatures. Ti deep levels have been measured by admittance spectroscopy. These deep levels are located at energies which vary from 0.20 to 0.28?eV below the conduction band for implantation doses in the range 1013-1014 at./cm2. For doses over the Mott limit, the implanted atoms become nonrecombinant. Capacitance voltage transient technique measurements prove that the fabricated devices consist of two-layers, in which the implanted layer and the substrate behave as an n+/n junction
High Intensity Low Temperature (HILT) performance of space concentrator GaInP/GaInAs/Ge MJ SCs

In the work, the results of an investigation of GaInP/GaInAs/Ge MJ SCs intended for converting concentrated solar radiation, when operating at low temperatures (down to -190 degrees C) are presented. A kink of the cell I-V characteristic has been observed in the region close to V-oc starting from -20 degrees C at operation under concentrated sunlight. The causes for its occurrence have been analyzed and the reasons for formation of a built-in potential barrier for majority charge carriers at the n-GaInP/n-Ge isotype hetero-interface are discussed. The effect of charge carrier transport in n-GaInP/n-p Ge heterostructures on MJ SC output characteristics at low temperatures has been studied including EL technique
Vegetation and fire history since the last glacial maximum in an inland area of the western Mediterranean Basin (Northern Iberian Plateau, NW Spain)

We reconstructed vegetation responses to climate oscillations, fire and human activities since the last glacial maximum in inland NW Iberia, where previous paleoecological research is scarce. Extremely sparse and open vegetation composed of steppic grasslands and heathlands with scattered pioneer trees suggests very cold and dry conditions during the Oldest Dryas, unsuitable for tree survival in the surroundings of the study site. Slight\ud
woodland expansion during the Bolling/Allerod was interrupted by the Younger Dryas cooling. Pinewoods\ud
dominated for most of the early Holocene, when a marked increase in fire activity occurred. Deciduous trees expanded later reaching their maximum representation during the mid-Holocene. Enhanced fire activity and the presence of coprophilous fungi around 6400-6000 cal yr BP suggest an early human occupation around the site. However, extensive deforestation only started at 4500 calyrBP, when fire was used to clear the tree canopy. Final replacement of woodlands with heathlands, grasslands and cereal crops occurred from 2700 cal yr BP\ud
onwards due to land-use intensification. Our paleoecological record can help efforts aimed at restoring the\ud
natural vegetation by indicating which communities were dominant at the onset of heavy human impact, thus\ud
promoting the recovery of currently rare oak and alder stands
Eventual election of multiple leaders for solving consensus in anonymous systems

In classical distributed systems, each process has a unique identity. Today, new distributed systems have emerged where a unique identity is not always possible to be assigned to each process. For example, in many sensor networks a unique identity is not possible to be included in each device due to its small storage capacity, reduced computational power, or the huge number of devices to be identified. In these cases, we have to work with anonymous distributed systems where processes cannot be identified. Consensus cannot be solved in classical and anonymous asynchronous distributed systems where processes can crash. To bypass this impossibility result, failure detectors are added to these systems. It is known that ? is the weakest failure detector class for solving consensus in classical asynchronous systems when amajority of processes never crashes. Although A? was introduced as an anonymous version of ?, to find the weakest failure detector in anonymous systems to solve consensus when amajority of processes never crashes is nowadays an open question. Furthermore, A? has the important drawback that it is not implementable. Very recently, A? has been introduced as a counterpart of ? for anonymous systems. In this paper, we show that the A? failure detector class is strictly weaker than A? (i.e., A? provides less information about process crashes than A?). We also present in this paper the first implementation of A? (hence, we also show that A? is implementable), and, finally, we include the first implementation of consensus in anonymous asynchronous systems augmented with A? and where a majority of processes does not crash
Cloud-native databases : an application perspective

As cloud computing technologies evolve to better support hosted software applications, software development businesses are faced with a multitude of options to migrate to the cloud. A key concern is the management of data. Research on cloud-native applications has guided the construction of highly elastically scalable and resilient stateless applications, while there is no corresponding concept for cloud-native databases yet. In particular, it is not clear what the trade-offs between using self-managed database services as part of the application and provider-managed database services are. We contribute an overview about the available options, a testbed to compare the options in a systematic way, and an analysis of selected benchmark results produced during the cloud migration of a commercial document management application
Density matrix functional theory that includes pairing correlations

The extension of density functional theory (DFT) to include pairing correlations without formal violation of the particle-number conservation condition is described. This version of the theory can be considered as a foundation of the application of existing DFT plus pairing approaches to atoms, molecules, ultracooled and magnetically trapped atomic Fermi gases, and atomic nuclei where the number of particles is conserved exactly. The connection with Hartree-Fock-Bogoliubov (HFB) theory is discussed, and the method of quasilocal reduction of the nonlocal theory is also described. This quasilocal reduction allows equations of motion to be obtained which are much simpler for numerical solution than the equations corresponding to the nonlocal case. Our theory is applied to the study of some even Sn isotopes, and the results are compared with those obtained in the standard HFB theory and with the experimental ones
In situ study of Ge(100) surfaces with tertiarybutylphosphine supply in vapor phase epitaxy ambient

GaInP nucleation on Ge(100) often starts by annealing of the Ge(100) substrates under supply of phosphorus precursors. However, the influence on the Ge surface is not well understood. Here, we studied vicinal Ge(100) surfaces annealed under tertiarybutylphosphine (TBP) supply in MOVPE by in situ reflection anisotropy spectroscopy (RAS), X-ray photoelectron spectroscopy (XPS), and low energy electron diffraction (LEED). While XPS reveals a P termination and the presence of carbon on the Ge surface, LEED patterns indicate a disordered surface probably due to by-products of the TBP pyrolysis. However, the TBP annealed Ge(100) surface exhibits a characteristic RA spectrum, which is related to the P termination. RAS allows us to in situ control phosphorus desorption dependent on temperature
Micromechanical modeling if the interactions between the microstructure and the dissipative deformation mechanisms in steels under cyclic loading

La version éditeur de cette publication est disponible à l'adresse suivante : 
http://www.sciencedirect.com/science/article/pii/S074964191100194XA micromechanical model is proposed to describe the interactions between the microstructure and the dissipative deformation mechanisms in ferritic steels under cyclic loading. The model aims at optimizing the microstructure of steels since the dissipative mechanisms can be responsible for the initiation of microcracks. Therefore, a better understanding of the influence of the microstructure could lead to an improvement of fatigue properties. The dissipative mechanisms are assumed to be either anelastic (dislocation oscillations) or inelastic (plastic slip) and are described at the scale of the slip system using the framework of crystal plasticity. The macroscopic behavior is then deduced with a homogenization scheme. The model is validated by comparing the simulations with experimental results and is finally used to predict the impact of different microstructure parameters on the heat dissipation