pinecone/core-2020-05-10-deduplication huggingface dataset:
The VIMOS Public Extragalactic Redshift Survey (VIPERS). Full
  spectroscopic data and auxiliary information release (PDR-2)

We present the full public data release (PDR-2) of the VIMOS Public
Extragalactic Redshift Survey (VIPERS), performed at the ESO VLT. We release
redshifts, spectra, CFHTLS magnitudes and ancillary information (as masks and
weights) for a complete sample of 86,775 galaxies (plus 4,732 other objects,
including stars and serendipitous galaxies); we also include their full
photometrically-selected parent catalogue. The sample is magnitude limited to
i_AB < 22.5, with an additional colour-colour pre-selection devised as to
exclude galaxies at z<0.5. This practically doubles the effective sampling of
the VIMOS spectrograph over the range 0.5<z<1.2 (reaching 47% on average),
yielding a final median local galaxy density close to 5 10^{-3} h^3 Mpc}^{-3}.
The total area spanned by the final data set is ~ 23.5 deg^2, corresponding to
288 VIMOS fields with marginal overlaps, split over two regions within the
CFHTLS-Wide W1 and W4 equatorial fields (at R.A. ~2 and ~22 hours,
respectively). Spectra were observed at a resolution R=220, covering a
wavelength range 5500-9500 Angstrom. Data reduction and redshift measurements
were performed through a fully automated pipeline; all redshift determinations
were then visually validated and assigned a quality flag. Measurements with a
quality flag >= 2 are shown to have a confidence level of 96% or larger and
make up 88% of all measured galaxy redshifts (76,552 out of 86,775),
constituting the VIPERS prime catalogue for statistical investigations. For
this sample the rms redshift error, estimated using repeated measurements of
about 3,000 galaxies, is found to be sigma_z = 0.00054(1+z). All data are
available at http://vipers.inaf.it and on the ESO Archive.Comment: Submitted to Astronomy and Astrophysics; 14 pages, 14 figures. High
  resolution version of Fig. 14 available at http://vipers.inaf.i
Structures of the Ultra-High-Affinity Protein-Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa.

How ultra-high-affinity protein-protein interactions retain high specificity is still poorly understood. The interaction between colicin DNase domains and their inhibitory immunity (Im) proteins is an ultra-high-affinity interaction that is essential for the neutralisation of endogenous DNase catalytic activity and for protection against exogenous DNase bacteriocins. The colicin DNase-Im interaction is a model system for the study of high-affinity protein-protein interactions. However, despite the fact that closely related colicin-like bacteriocins are widely produced by Gram-negative bacteria, this interaction has only been studied using colicins from Escherichia coli. In this work, we present the first crystal structures of two pyocin DNase-Im complexes from Pseudomonas aeruginosa, pyocin S2 DNase-ImS2 and pyocin AP41 DNase-ImAP41. These structures represent divergent DNase-Im subfamilies and are important in extending our understanding of protein-protein interactions for this important class of high-affinity protein complex. A key finding of this work is that mutations within the immunity protein binding energy hotspot, helix III, are tolerated by complementary substitutions at the DNase-Immunity protein binding interface. Im helix III is strictly conserved in colicins where an Asp forms polar interactions with the DNase backbone. ImAP41 contains an Asp-to-Gly substitution in helix III and our structures show the role of a co-evolved substitution where Pro in DNase loop 4 occupies the volume vacated and removes the unfulfilled hydrogen bond. We observe the co-evolved mutations in other DNase-Immunity pairs that appear to underpin the split of this family into two distinct groups
c-Map for Born-Infeld theories

The c-map of four dimensional non-linear theories of electromagnetism is considered both in the rigid case and in its coupling to gravity. In this way theories with antisymmetric tensors and scalars are obtained, and the three non-linear representations of N = 2 supersymmetry partially broken to N = 1 related. The manifest Sp(2n)xSp(2n) and U(n)xU(n) covariance of these theories in their multifield extensions is also exhibited. This construction extends to H-invariant non-linear theories of Born-Infeld type with non-dynamical scalars spanning a symmetric coset manifold G/H and the vector field strengths and their duals in a symplectic representation of G as is the case for extended supergravit
Attitude, knowledge and perception of the altruistic\ud
donation of blood in a city in Northeastern Mexico

Objectives: To identify the causes due to which potential blood donors do not make voluntary donations: lack of knowledge, attitude, and the perception of blood donations as unwholesome. Materials and methods: We conducted a transversal, observational, descriptive, prospective, and a survey-based study of 435 subjects in Monterrey, Mexico in November of 2011. Results: 135 (31%) subjects were already donors, of which only 16 (3.6%) did it altruistically. Of the total amount of subjects, 161 (37%) were associated with some benefits from donating blood, 154 (35%) identified some kind of damage, the most mentioned was transmission of diseases with 77 (50%) mentions. The most common cause of refusal toward donation was ‘‘saving blood for a relative in need’’ with 137 (33%) mentions. Of the subjects surveyed, 55% (n = 240) refer having very few thoughts for donating blood voluntarily. Also, 360 (86%) subjects will donate\ud
without expecting something in return. Finally, 348 (80%) subjects do not remember seeing or hearing any kind of promotional information about altruistic blood donation.\ud
Conclusions: A great deal of people will donate blood altruistically without receiving any reward for doing so. 80% of the subjects do not remember seeing or hearing any kind of advertisement for blood donation which is proof of lack of adequate publicity. The analysis of perception of damages or benefits from blood donation will help in the development of more focused blood\ud
donation campaigns
The relationship between parental education and children's schooling in a time of economic turmoil: The case of East Zimbabwe, 2001 to 2011.

Using data collected from 1998 to 2011 in a general population cohort study in eastern Zimbabwe, we describe education trends and the relationship between parental education and children's schooling during the Zimbabwean economic collapse of the 2000s. During this period, the previously-rising trend in education stalled, with girls suffering disproportionately; however, female enrolment increased as the economy began to recover. Throughout the period, children with more educated parents continued to have better outcomes such that, at the population level, an underlying increase in the proportion of children with more educated parents may have helped to maintain the upwards education trend
Scenario planning to leap-frog the Sustainable Development Goals:An adaptation pathways approach

Few studies have examined how to mainstream future climate change uncertainty into decision-making for poverty alleviation in developing countries. With potentially drastic climate change emerging later this century, there is an imperative to develop planning tools which can enable vulnerable rural communities to proactively build adaptive capacity and 'leap-frog' the Sustainable Development Goals (SDGs). Using an example from Indonesia, we present a novel participatory approach to achieve this. We applied scenario planning to operationalise four adaptation pathways principles: (1) consideration of climate change as a component of multi-scale social-ecological systems; (2) recognition of stakeholders' competing values, goals and knowledge through co-learning; (3) coordination of responses across multiple decision-making levels; and (4) identification of strategies which are 'no regrets', incremental (tackling proximate drivers of community vulnerability) and transformative (tackling systemic drivers). Workshops with stakeholders from different administrative levels identified drivers of change, an aspirational vision and explorative scenarios for livelihoods in 2090, and utilised normative back-casting to design no regrets adaptation strategies needed to achieve the vision. The resulting 'tapestry' of strategies were predominantly incremental, and targeted conventional development needs. Few directly addressed current or possible future climate change impacts. A minority was transformative, and higher level stakeholders identified proportionately more transformative strategies than local level stakeholders. Whilst the vast majority of strategies were no regrets, some were potentially mal-adaptive, particularly for coastal areas and infrastructure. There were few examples of transformative innovations that could generate a step-change in linked human and environmental outcomes, hence leap-frogging the SDGs. We conclude that whilst effective at integrating future uncertainties into community development planning, our approach should place greater emphasis on analysing and addressing systemic drivers through extended learning cycles
Sparse aperture masking interferometry survey of transitional discs: Search for substellar-mass companions and asymmetries in their parent discs

This is the author accepted manuscript. The final version is available from EDP Sciences via the DOI in this record.Context. Transitional discs are a class of circumstellar discs around young stars with extensive clearing of dusty material within their
inner regions on 10s of au scales. One of the primary candidates for this kind of clearing is the formation of planet(s) within the disc
that then accrete or clear their immediate area as they migrate through the disc.
Aims. The goal of this survey was to search for asymmetries in the brightness distribution around a selection of transitional disc
targets. We then aimed to determine whether these asymmetries trace dynamically-induced structures in the disc or the gap-opening
planets themselves.
Methods. Our sample included eight transitional discs. Using the Keck/NIRC2 instrument we utilised the Sparse Aperture Masking
(SAM) interferometry technique to search for asymmetries indicative of ongoing planet formation. We searched for close-in companions
using both model fitting and interferometric image reconstruction techniques. Using simulated data, we derived diagnostics that
helped us to distinguish between point sources and extended asymmetric disc emission. In addition, we investigated the degeneracy
between the contrast and separation that appear for marginally resolved companions.
Results. We found FP Tau to contain a previously unseen disc wall, and DM Tau, LkHα330, and TW Hya to contain an asymmetric
signal indicative of point source-like emission. We placed upper limits on the contrast of a companion in RXJ1842.9-3532 and
V2246 Oph. We ruled the asymmetry signal in RXJ1615.3-3255 and V2062 Oph to be false positives. In the cases where our data
indicated a potential companion we computed estimates for the value of McM˙
c and found values in the range of 10−5 − 10−3M2
J
yr−1
.
Conclusions. We found significant asymmetries in four targets. Of these, three were consistent with companions. We resolved a
previously unseen gap in the disc of FP Tau extending inwards from approximately 10 au.We acknowledge support from a STFC Rutherford Fellowship
 and Grant (ST/J004030/1, ST/K003445/1), Marie Sklodowska-Curie CIG
 grant (Ref. 618910), and Philip Leverhulme Prize (PLP-2013-110). We additionally
 acknowledge support from NASA KPDA grants (JPL-1452321, 1474717,
 1485953, 1496788). The authors wish to recognise and acknowledge the very
 significant cultural role and reverence that the summit of Mauna Kea has always
 had within the indigenous Hawaiian community. We are most fortunate to have
 the opportunity to conduct observations from this mountain. Some of the data
 presented herein were obtained at the W.M. Keck Observatory, which is operated
 as a scientific partnership among the California Institute of Technology, the
 University of California and the National Aeronautics and Space Administration.
 The Observatory was made possible by the generous financial support of
 the W.M. Keck Foundatio
Search for the Higgs boson in the H → WW → ℓvjj decay channel at √s = 7 TeV with the ATLAS detector

A search for the Standard Model Higgs boson has been performed in the H→WW→ℓνjj channel using 4.7 fb[superscript −1] of pp collision data recorded at a centre-of-mass energy of √s = 7 TeV with the ATLAS detector at the Large Hadron Collider. Higgs boson candidates produced in association with zero, one or two jets are included in the analysis to maximize the acceptance for both gluon fusion and weak boson fusion Higgs boson production processes. No significant excess of events is observed over the expected background and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 300 GeV < [subscript mH] < 600 GeV. The best sensitivity is reached for [subscript mH] = 400 GeV, where the observed (expected) 95% confidence level upper bound on the cross section for H→WW produced in association with zero or one jet is 2.2 pb (1.9 pb), corresponding to 1.9 (1.6) times the Standard Model prediction. In the Higgs boson plus two jets channel, which is more sensitive to the weak boson fusion process, the observed (expected) 95% confidence level upper bound on the cross section for H→WW production with [subscript mH] = 400 GeV is 0.7 pb (0.6 pb), corresponding to 7.9 (6.5) times the Standard Model prediction.European Organization for Nuclear ResearchUnited States. Dept. of EnergyNational Science Foundation (U.S.)Brookhaven National Laborator
A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

MicroRNAs are well suited to regulate tumor metastasis because of their capacity to coordinately repress numerous target genes, thereby potentially enabling their intervention at multiple steps of the invasion-metastasis cascade. We identify a microRNA exemplifying these attributes, miR-31, whose expression correlates inversely with metastasis in human breast cancer patients. Overexpression of miR-31 in otherwise-aggressive breast tumor cells suppresses metastasis. We deploy a stable microRNA sponge strategy to inhibit miR-31 in vivo; this allows otherwise-nonaggressive breast cancer cells to metastasize. These phenotypes do not involve confounding influences on primary tumor development and are specifically attributable to miR-31-mediated inhibition of several steps of metastasis, including local invasion, extravasation or initial survival at a distant site, and metastatic colonization. Such pleiotropy is achieved via coordinate repression of a cohort of metastasis-promoting genes, including RhoA. Indeed, RhoA re-expression partially reverses miR-31-imposed metastasis suppression. These findings indicate that miR-31 uses multiple mechanisms to oppose metastasis.Massachusetts Institute of Technology (Daniel K. Ludwig Foundation Cancer Research Professor)American Cancer Society (ACS Research Professor)United States. Dept. of Defense (Breast Cancer Research Program Predoctoral Fellow)United States. Dept. of Defense (Breast Cancer Research Program, DoD BCRP Idea Award))Harvard University (Harvard Breast Cancer SPORE)National Institutes of Health (U.S.) (RO1 CA078461)National Institutes of Health (U.S.) (PO1 CA080111
SWIFT X-RAY TELESCOPE STUDY OF THE BLACK HOLE BINARY MAXI J1659–152: VARIABILITY FROM A TWO COMPONENT ACCRETION FLOW

We present an energy dependent X-ray variability study of the 2010 outburst of the black hole X-ray binary MAXI J1659–152 with the Swift X-ray Telescope (XRT). The broadband noise components and the quasi-periodic oscillations (QPO) observed in the power spectra show a strong and varied energy dependence. Combining Swift XRT data with data from the Rossi X-ray Timing Explorer, we report, for the first time, an rms spectrum (fractional rms amplitude as a function of energy) of these components in the 0.5–30 keV energy range. We find that the strength of the low-frequency component (<0.1 Hz) decreases with energy, contrary to the higher frequency components (>0.1 Hz) whose strengths increase with energy. In the context of the propagating fluctuations model for X-ray variability, we suggest that the low-frequency component originates in the accretion disk (which dominates emission below ~2 keV) and the higher frequency components are formed in the hot flow (which dominates emission above ~2 keV). As the properties of the QPO suggest that it may have a different driving mechanism, we investigate the Lense–Thirring precession of the hot flow as a candidate model. We also report on the QPO coherence evolution for the first time in the energy band below 2 keV. While there are strong indications that the QPO is less coherent at energies below 2 keV than above 2 keV, the coherence increases with intensity similar to what is observed at energies above 2 keV in other black hole X-ray binaries
Pkd1 regulates lymphatic vascular morphogenesis during development

Lymphatic vessels arise during development through sprouting of precursor cells from veins, which is regulated by known signaling and transcriptional mechanisms. The ongoing elaboration of vessels to form a network is less well understood. This involves cell polarization, coordinated migration, adhesion, mixing, regression, and shape rearrangements. We identified a zebrafish mutant, lymphatic and cardiac defects 1 (lyc1), with reduced lymphatic vessel development. A mutation in polycystic kidney disease 1a was responsible for the phenotype. PKD1 is the most frequently mutated gene in autosomal dominant polycystic kidney disease (ADPKD). Initial lymphatic precursor sprouting is normal in lyc1 mutants, but ongoing migration fails. Loss of Pkd1 in mice has no effect on precursor sprouting but leads to failed morphogenesis of the subcutaneous lymphatic network. Individual lymphatic endothelial cells display defective polarity, elongation, and adherens junctions. This work identifies a highly selective and unexpected role for Pkd1 in lymphatic vessel morphogenesis during development.Baptiste Coxam, Amélie Sabine, Neil I. Bower, Kelly A. Smith, Cathy Pichol-Thievend, Renae Skoczylas, Jonathan W. Astin, Emmanuelle Frampton, Muriel Jaquet, Philip S. Crosier, Robert G. Parton, Natasha L. Harvey, Tatiana V. Petrova, Stefan Schulte-Merker, Mathias Francois, Benjamin M. Hoga
Gauge coupling field, currents, anomalies and N=1 super-Yang–Mills effective actions

Working with a gauge coupling field in a linear superfield, we construct effective Lagrangians for N=1 super-Yang–Mills theory fully compatible with the expected all-order behavior or physical quantities. Using the one-loop dependence on its ultraviolet cutoff and anomaly matching or cancellation of R and dilatation anomalies, we obtain the Wilsonian effective Lagrangian. With similar anomaly matching or cancellation methods, we derive the effective action for gaugino condensates, as a function of the real coupling field. Both effective actions lead to a derivation of the NSVZ β   function from algebraic arguments only. The extension of results to N=2 theories or to matter systems is briefly considered. The main tool for the discussion of anomalies is a generic supercurrent structure with 16B+16F operators (the S multiplet), which we derive using superspace identities and field equations for a fully general gauge theory Lagrangian with the linear gauge coupling superfield, and with various U(1)R currents. As a byproduct, we show under which conditions the S multiplet can be improved to contain the Callan–Coleman–Jackiw energy-momentum tensor whose trace measures the breaking of scale invariance
Optimization of protein samples for NMR using thermal shift assays

Maintaining a stable fold for recombinant proteins is challenging, especially when working with highly purified and concentrated samples at temperatures &gt;20 °C. Therefore, it is worthwhile to screen for different buffer components that can stabilize protein samples. Thermal shift assays or ThermoFluor® provide a high-throughput screening method to assess the thermal stability of a sample under several conditions simultaneously. Here, we describe a thermal shift assay that is designed to optimize conditions for nuclear magnetic resonance studies, which typically require stable samples at high concentration and ambient (or higher) temperature. We demonstrate that for two challenging proteins, the multicomponent screen helped to identify ingredients that increased protein stability, leading to clear improvements in the quality of the spectra. Thermal shift assays provide an economic and time-efficient method to find optimal conditions for NMR structural studies. © 2016, The Author(s).EU/FP7/2007–2013European Molecular Biology LaboratoryEMBO Long-term Fellowshi
Search for the Xb and other hidden-beauty states in the π+π-ϒ(1S) channel at ATLAS

This Letter presents a search for a hidden-beauty counterpart of the X(3872) in the mass ranges of 10.05-10.31 GeV and 10.40-11.00 GeV, in the channel Xb→π+π-ϒ(1S)(→μ+μ-), using 16.2 fb-1 of √s=8 TeV pp collision data collected by the ATLAS detector at the LHC. No evidence for new narrow states is found, and upper limits are set on the product of the Xb cross section and branching fraction, relative to those of the ϒ(2S), at the 95% confidence level using the CLS approach. These limits range from 0.8% to 4.0%, depending on mass. For masses above 10.1 GeV, the expected upper limits from this analysis are the most restrictive to date. Searches for production of the ϒ(13DJ), ϒ(10860), and ϒ(11020) states also reveal no significant signalsWe thank CERN for the very successful operation of the LHC,
as well as the support staff from our institutions without whom
ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI,
Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan;
SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC
and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC,
China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR,
Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark;
EPLANET, ERC and NSRF, European Union; IN2P3-CNRS,
CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and
AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA,
GIF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and
JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF
and RCN, Norway; MNiSW and NCN, Poland; GRICES and FCT,
Portugal; MNE/IFA, Romania; MES of Russia and ROSATOM, Russian
Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and
MIZŠ, Slovenia; DST/NRF, South Africa; MINECO, Spain; SRC and
Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern
and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the
Royal Society and Leverhulme Trust, United Kingdom; DOE and
NSF, United States of America.
The crucial computing support from all WLCG partners is acknowledged
gratefully, in particular from CERN and the ATLAS Tier-
1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden),
CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy),
NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL
(USA) and in the Tier-2 facilities worldwid