pinecone/core-2020-05-10-deduplication huggingface dataset:
Situating disability. The recognition of “handicapped workers” in France

International audienceThis article concerns the issues surrounding the " Recognition of the Quality of Handicapped Workers " in France, from both applicants " and decision-makers " points of view. While the latter strive to make " handicapped workers " into a sub-category of disabled persons, applicants " positions are often more ambivalent. In speaking of their experience, many of them use the notion of " situation of handicap, " a term quite common in current French debates about disability that was not retained in the French law of 2005: even if they are bothered by a functional difficulty in certain professional situations, many still do not think of themselves as disabled persons. To understand these differences, we propose returning to the foundations of French employment policy in favour of disabled persons and exploring the variety of issues that dominate claims to recognition, without forgetting the essential interface role played by professionals in the field of disability. Our analysis is based on a field study on both sides of the counter at Departmental Centres for Handicapped Persons, with people working in the institutions and those requesting recognition of the quality of disabled worker
Unlocking the zinc isotope systematics of iron meteorites

Zinc isotope compositions (δ66Zn) and concentrations were determined for metal samples of 15 iron meteorites across groups IAB, IIAB, and IIIAB. Also analyzed were troilite and other inclusions from the IAB iron Toluca. Furthermore, the first Zn isotope data are presented for metal–silicate partitioning experiments that were conducted at 1.5 GPa and 1650 K. Three partitioning experiments with run durations of between 10 and 60 min provide consistent Zn metal–silicate partition coefficients of ∼0.7 and indicate that Zn isotope fractionation between molten metal and silicate is either small (at less than about ±0.2‰±0.2‰) or absent. Metals from the different iron meteorite groups display distinct ranges in Zn contents, with concentrations of 0.08–0.24 μg/g for IIABs, 0.8–2.5 μg/g for IIIABs, and 12–40 μg/g for IABs. In contrast, all three groups show a similar range of δ66Zn values (reported relative to ‘JMC Lyon Zn’) from +0.5‰+0.5‰ to +3.0‰+3.0‰, with no clear systematic differences between groups. However, distinct linear trends are defined by samples from each group in plots of δ66Zn vs. 1/Zn, and these correlations are supported by literature data. Based on the high Zn concentration and δ66Zn ≈ 0 determined for a chromite-rich inclusion of Toluca, modeling is employed to demonstrate that the Zn trends are best explained by segregation of chromite from the metal phase. This process can account for the observed Zn–δ66Zn–Cr systematics of iron meteorite metals, if Zn is highly compatible in chromite and Zn partitioning is accompanied by isotope fractionation with Δ66Znchr-met≈−1.5‰≈−1.5‰. Based on these findings, it is likely that the parent bodies of the IAB complex, IIAB and IIIAB iron meteorites featured δ66Zn values of about −1.0 to +0.5‰+0.5‰, similar to the Zn isotope composition inferred for the bulk silicate Earth and results obtained for chondritic meteorites. Together, this implies that most solar system bodies formed with similar bulk Zn isotope compositions despite large differences in Zn contents
On the convergence to the multiple Wiener-Ito integral

International audienceWe study the convergence to the multiple Wiener-It\^{o} integral from processes with absolutely continuous paths. More precisely, consider a family of processes, with paths in the Cameron-Martin space, that converges weakly to a standard Brownian motion in $\mathcal C_0([0,T])$. Using these processes, we construct a family that converges weakly, in the sense of the finite dimensional distributions, to the multiple Wiener-It\^{o} integral process of a function $f\in L^2([0,T]^n)$. We prove also the weak convergence in the space $\mathcal C_0([0,T])$ to the second order integral for two important families of processes that converge to a standard Brownian motion
"Paperless" Foreign Languages Teaching

The paper is focused on the integration of the "paperless" technology in English for Specific Purposes and General English teaching-learning process of power engineering students. This technology is an efficient way to realize the functions of the e-learning environment (Moodle, blogs, etc.) of a modern institution of higher education. It creates the conditions for independent acquisition and quality mastering of necessary learning information which can be used at foreign language lessons. The use of electronic teaching materials based on hypertext and multimedia tools clearly demonstrated the advantages of this technology compared with traditional textbooks since it allows revealing the didactic potential of information technologies
Controllability of a 2 × 2 parabolic system by one force with space-dependent coupling term of order one

International audienceThis paper is devoted to the controllability of linear systems of two coupled parabolic equations when the coupling involves a space dependent first order term. This system is set on an bounded interval I ⊂⊂ R, and the first equation is controlled by a force supported in a subinterval of I or on the boundary. In the case where the intersection of the coupling and control domains is nonempty, we prove null controllability at any time. Otherwise, we provide a minimal time for null controllability. Finally we give a necessary and sufficient condition for the approximate controllability. The main technical tool for obtaining these results is the moment method
Polycyclic Aromatic Hydrocarbons Pollution in a Coastal Environment: the Statistical Analysis of Dependence to Estimate the Source of Pollution

Polycyclic Aromatic Hydrocarbons (PAHs) are a group of carcinogenic contaminants widespread in the environment. PAHs are produced by both anthropogenic and natural processes. Difficulties exist in identifying their origins. This paper reports a practical application of Principal Component Analysis (PCA) and Principal Component Regression (PCR) to identify the pyrolytic, petrogenic and diagenesis sources of PAH pollution in the Sarno River and Estuary. Nicknamed "the most polluted river in Europe", the Sarno River originates in south-western Italy and has a watershed of about 715 km(2). PCA indicated that the PAH contamination in the Sarno River and Estuary resulted from a mixed pattern. The first principal component (PC1) had significant positive loading in high molecular weight PAHs. This profile of PAH usually includes products of high temperature combustion/pyrolitic processes, reflecting the effects of traffic pyrolysis. The second principal component (PC2) had significant positive loading in two-to-four ring PAHs. So, PC2 may be considered as components from petrogenic sources. PC3 was characterized by a high loading of perylene, thought to originate from diagenetic alteration of perylenequinone pigment or some other organic matter. Therefore, this factor can be considered as natural-origin PAHs. In the PCR, the regression coefficients for components 1-3 were 66.6, 40.4 and 19.5, respectively. In this application, the PCR was a very useful statistical technique for handling the problem of multicollinearity. Results from the application of PCR have been compared with Partial Least Square (PLS) and no significant differences were reported in the prediction errors and latent variables available by PCR and PLS
Search for a Higgs boson decaying into a Z and a photon in pp collisions at √s=7 and 8TeV

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMA search for a Higgs boson decaying into a Z boson and a photon is described. The analysis is performed using proton–proton collision datasets recorded by the CMS detector at the LHC. Events were collected at center-of-mass energies of 7 TeV and 8 TeV, corresponding to integrated luminosities of 5.0 fb−1 and 19.6 fb−1, respectively. The selected events are required to have opposite-sign electron or muon pairs. No excess above standard model predictions has been found in the 120–160 GeV mass range and the first limits on the Higgs boson production cross section times the H→Zγ branching fraction at the LHC have been derived. The observed at 95% confidence level limits are between about 4 and 25 times the standard model cross section times the branching fraction. For a standard model Higgs boson mass of 125 GeV the expected limit at the 95% confidence level is 10 and the observed limit is 9.5. Models predicting the Higgs boson production cross section times the H→Zγ branching fraction to be larger than one order of magnitude of the standard model prediction are excluded for most of the 125–157 GeV mass rangeWe congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centres and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Republic of Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS and RFBR (Russia); MESTD (Serbia); SEIDI and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); ThEPCenter, IPST, STAR and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA
Positive youth development, life satisfaction and problem behaviour among Chinese adolescents in Hong Kong : a replication

The purpose of this replication study was to examine the relationships among life satisfaction, positive youth development and problem behaviour. The respondents were 7,151 Chinese Secondary 2 (Grade 8) students (3,707 boys and 3,014 girls) recruited from 44 schools in Hong Kong. Validated assessment tools measuring positive youth development, life satisfaction and problem behaviour were used. As predicted, positive youth development was positively correlated with life satisfaction, and positive youth development and life satisfaction were negatively correlated with adolescent problem behaviour. Based on a series of structural equation models, the present findings replicated the previous findings that adolescents with a higher level of positive youth development were more satisfied with life and had lesser problem behaviour, with higher level of life satisfaction and lower level of problem behaviour mutually influencing each other. These replicated findings provide a further advance in the literature on positive youth development, particularly in the Chinese context. Implications for future research and intervention were discussed.Department of Applied Social Sciences2011-2012 > Academic research: refereed > Publication in refereed journalpublished_fina
Limits on neutral Higgs boson production in the forward region in pp collisions at root s=7 TeV

Limits on the cross-section times branching fraction for neutral Higgs bosons, produced in p p collisions at root s = 7 TeV, and decaying to two tau leptons with pseudorapidities between 2.0 and 4.5, are presented. The result is based on a dataset, corresponding to an integrated luminosity of 1.0 fb(-1), collected with the LHCb detector. Candidates are identified by reconstructing final states with two muons, a muon and an electron, a muon and a hadron, or an electron and a hadron. A model independent upper limit at the 95% confidence level is set on a neutral Higgs boson cross-section times branching fraction. It varies from 8.6 pb for a Higgs boson mass of 90 GeV to 0.7 pb for a Higgs boson mass of 250 GeV, and is compared to the Standard Model expectation. An upper limit on tan beta in the Minimal Supersymmetric Model is set in the m(h0)(max) scenario. It ranges from 34 for a CP-odd Higgs boson mass of 90 GeV to 70 for a pseudo-scalar Higgs boson mass of 140 GeV
Observation of Upsilon(1S) pair production in proton-proton collisions
  at sqrt(s) = 8 TeV

Pair production of Upsilon(1S) mesons is observed at the LHC in proton-proton
collisions at sqrt(s) = 8 TeV by the CMS experiment in a data sample
corresponding to an integrated luminosity of 20.7 inverse femtobarns. Both
Upsilon(1S) candidates are fully reconstructed via their decays to mu+ mu-. The
fiducial acceptance region is defined by an absolute Upsilon(1S) rapidity
smaller than 2.0. The fiducial cross section for the production of Upsilon(1S)
pairs, assuming that both mesons decay isotropically, is measured to be 68.8
+/- 12.7 (stat) +/- 7.4 (syst) +/- 2.8 (B) pb, where the third uncertainty
comes from the uncertainty in the branching fraction of Upsilon(1S) decays to
mu+ mu-. Assuming instead that the Upsilon(1S) mesons are produced with
different polarizations leads to variations in the measured cross section in
the range from -38% to +36%.Comment: Replaced with the published version. Added the journal reference and
  DOI. All figures and tables can be found at
  http://cms-results.web.cern.ch/cms-results/public-results/publications/BPH-14-008/index.htm
Essential competencies in prescribing : a first European cross-sectional study among 895 final-year medical students

European medical students should have acquired adequate prescribing competencies before graduation, but it is not known whether this is the case. In this international multicenter study, we evaluated the essential knowledge, skills, and attitudes in clinical pharmacology and therapeutics (CPT) of final-year medical students across Europe. In a cross-sectional design, 26 medical schools from 17 European countries were asked to administer a standardized assessment and questionnaire to 50 final-year students. Although there were differences between schools, our results show an overall lack of essential prescribing competencies among final-year students in Europe. Students had a poor knowledge of drug interactions and contraindications, and chose inappropriate therapies for common diseases or made prescribing errors. Our results suggest that undergraduate teaching in CPT is inadequate in many European schools, leading to incompetent prescribers and potentially unsafe patient care. A European core curriculum with clear learning outcomes and assessments should be urgently developed
The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species.

Published onlineJOURNAL ARTICLEMethyl-aminolevulinate-based photodynamic therapy (MAL-PDT) is utilised clinically for the treatment of non-melanoma skin cancers and pre-cancers and the hydroxypyridinone iron chelator, CP94, has successfully been demonstrated to increase MAL-PDT efficacy in an initial clinical pilot study. However, the biochemical and photochemical processes leading to CP94-enhanced photodynamic cell death, beyond the well-documented increases in accumulation of the photosensitiser protoporphyrin IX (PpIX), have not yet been fully elucidated. This investigation demonstrated that MAL-based photodynamic cell killing of cultured human squamous carcinoma cells (A431) occurred in a predominantly necrotic manner following the generation of singlet oxygen and ROS. Augmenting MAL-based photodynamic cell killing with CP94 co-treatment resulted in increased PpIX accumulation, MitoSOX-detectable ROS generation (probably of mitochondrial origin) and necrotic cell death, but did not affect singlet oxygen generation. We also report (to our knowledge, for the first time) the detection of intracellular PpIX-generated singlet oxygen in whole cells via electron paramagnetic resonance spectroscopy in conjunction with a spin trap.We thank Professor Robert Hider, King's College London, for providing the iron chelating agent (CP94), and Drs Paul Eggleton and Jo Tarr (University of Exeter Medical School) for their assistance with the flow cytometry analysis. The Duchy Health Charity Ltd (DCH05-07), Peninsula Medical School and DDRC Healthcare (GD100015-122) are thanked for financial support. PGW and DCJF acknowledge financial support from the European Cooperation in Science and Technology, Belgium (COST Action BM1203/EU-ROS)
Chemical solver to compute molecule and grain abundances and non-ideal MHD resistivities in prestellar core collapse calculations

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.We develop a detailed chemical network relevant to the conditions characteristic of prestellar core collapse. We solve the system of time-dependent differential equations to calculate the equilibrium abundances of molecules and dust grains, with a size distribution given by size-bins for these latter. These abundances are used to compute the different non-ideal magneto-hydrodynamics resistivities (ambipolar, Ohmic and Hall), needed to carry out simulations of protostellar collapse. For the first time in this context, we take into account the evaporation of the grains, the thermal ionisation of Potassium, Sodium and Hydrogen at high temperature, and the thermionic emission of grains in the chemical network, and we explore the impact of various cosmic ray ionisation rates. All these processes significantly affect the non-ideal magneto-hydrodynamics resistivities, which will modify the dynamics of the collapse. Ambipolar diffusion and Hall effect dominate at low densities, up to n_H = 10^12 cm^-3, after which Ohmic diffusion takes over. We find that the time-scale needed to reach chemical equilibrium is always shorter than the typical dynamical (free fall) one. This allows us to build a large, multi-dimensional multi-species equilibrium abundance table over a large temperature, density and ionisation rate ranges. This table, which we make accessible to the community, is used during first and second prestellar core collapse calculations to compute the non-ideal magneto-hydrodynamics resistivities, yielding a consistent dynamical-chemical description of this process
Taking forward the World TB Day 2016 Theme 'Unite to End Tuberculosis' for the WHO Africa Region.

Tuberculosis (TB) remains a global emergency, with an estimated 9.6 million new TB cases worldwide reported in 2014. Twenty-eight percent of these cases were in the World Health Organization (WHO) Africa Region, where the annual case detection rate was 281 per 100000 population-more than double the global average of 133 per 100000. Of the 9.6 million people who developed TB, an estimated 1.2 million (12%) were HIV-positive, and the Africa Region accounted for 74% of these cases. Three million people with TB remain undiagnosed and untreated. Globally, an estimated 480000 had multidrug-resistant TB (MDR-TB). Whilst of the African countries, only South Africa has reported a high prevalence of MDR-TB, it is likely that all of Sub-Saharan Africa has an unreported high load of drug-resistant TB. Tragically, in 2014, only 48% of individuals diagnosed with MDR-TB had successful treatment and an estimated 190000 people died of MDR-TB. Of the global TB funding gap of US$ 0.8 billion, the largest funding gap was in the Africa Region, amounting to US$ 0.4 billion in 2015. The MDR-TB pandemic in particular now threatens to devastate entire regions and may fundamentally alter the life-expectancy and demographic profile of many countries in Sub-Saharan Africa. The theme designated for this year's World TB Day, March 24, 2016, is 'Unite to End TB'. From the Africa Region, there is an urgent need to seriously address the political, economic, and social factors that influence host-Mycobacterium tuberculosis interactions and result in disease. Recent political and funder initiatives that provide renewed hope for the alleviation of Africa's TB and TB/HIV problems are discussed
Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment.

High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010.
We used data for exposure to risk factors by country, age group, and sex from pooled analyses of population-based health surveys. We obtained relative risks for the effects of risk factors on cause-specific mortality from meta-analyses of large prospective studies. We calculated the population attributable fractions for each risk factor alone, and for the combination of all risk factors, accounting for multicausality and for mediation of the effects of BMI by the other three risks. We calculated attributable deaths by multiplying the cause-specific population attributable fractions by the number of disease-specific deaths. We obtained cause-specific mortality from the Global Burden of Diseases, Injuries, and Risk Factors 2010 Study. We propagated the uncertainties of all the inputs to the final estimates.
In 2010, high blood pressure was the leading risk factor for deaths due to cardiovascular diseases, chronic kidney disease, and diabetes in every region, causing more than 40% of worldwide deaths from these diseases; high BMI and glucose were each responsible for about 15% of deaths, and high cholesterol for more than 10%. After accounting for multicausality, 63% (10·8 million deaths, 95% CI 10·1-11·5) of deaths from these diseases in 2010 were attributable to the combined effect of these four metabolic risk factors, compared with 67% (7·1 million deaths, 6·6-7·6) in 1980. The mortality burden of high BMI and glucose nearly doubled from 1980 to 2010. At the country level, age-standardised death rates from these diseases attributable to the combined effects of these four risk factors surpassed 925 deaths per 100 000 for men in Belarus, Kazakhstan, and Mongolia, but were less than 130 deaths per 100 000 for women and less than 200 for men in some high-income countries including Australia, Canada, France, Japan, the Netherlands, Singapore, South Korea, and Spain.
The salient features of the cardiometabolic disease and risk factor epidemic at the beginning of the 21st century are high blood pressure and an increasing effect of obesity and diabetes. The mortality burden of cardiometabolic risk factors has shifted from high-income to low-income and middle-income countries. Lowering cardiometabolic risks through dietary, behavioural, and pharmacological interventions should be a part of the global response to non-communicable diseases.
UK Medical Research Council, US National Institutes of Health