pinecone/core-2020-05-10-deduplication huggingface dataset:
Search for quark contact interactions in dijet angular distributions in pp collisions at root s=7 TeV measured with the ATLAS detector

Dijet angular distributions from the first LHC pp collisions at center-of-mass energy root s = 7 TeV have been measured with the ATLAS detector. The dataset used for this analysis represents an integrated luminosity of 3.1 pb(-1). Dijet chi distributions and centrality ratios have been measured up to dijet masses of 2.8 TeV, and found to be in good agreement with Standard Model predictions. Analysis of the chi distributions excludes quark contact interactions with a compositeness scale Lambda below 3.4 TeV, at 95% confidence level, significantly exceeding previous limits
Discrimination of speech sounds by children with dyslexia: Comparisons with chronological age and reading level controls

International audiencePrevious studies have shown that children suffering from develop- mental dyslexia have a deﬁcit in categorical perception of speech sounds. The aim of the current study was to better understand the nature of this categorical perception deﬁcit. In this study, cat- egorical perception skills of children with dyslexia were compared with those of chronological age and reading level controls. Children identiﬁed and discriminated /do–to/ syllables along a voice onset time (VOT) continuum. Results showed that children with dyslexia discriminated among phonemically contrastive pairs less accu- rately than did chronological age and reading level controls and also showed higher sensitivity in the discrimination of allophonic contrasts. These results suggest that children with dyslexia per- ceive speech with allophonic units rather than phonemic units. The origin of allophonic perception in the course of perceptual development and its implication for reading acquisition are discussed
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer

Estrogen receptor alpha (ERalpha) is the key transcriptional driver in a large proportion of breast cancers. We report that APOBEC3B (A3B) is required for regulation of gene expression by ER and acts by causing C-to-U deamination at ER  binding regions. We show that these C-to-U changes lead to the generation of DNA  strand breaks through activation of base excision repair (BER) and to repair by non-homologous end-joining (NHEJ) pathways. We provide evidence that transient cytidine deamination by A3B aids chromatin modification and remodelling at the regulatory regions of ER target genes that promotes their expression. A3B expression is associated with poor patient survival in ER+ breast cancer, reinforcing the physiological significance of A3B for ER action
Water vapor oxidation of ferritic 441 and austenitic 316L stainless steels at 1100 °C for short duration

This is an open access article under the CC BY-NC-ND license http://creativecommons.org/licenses/by-nc-nd/4.0/International audienceA ferritic 441 and an austenitic 316L steels have been exposed to wet argon at 1100 °C. This study focus on the characterization of the oxide scales formed after different exposure times in the range of 2.5-20 min. Raman spectroscopy, XRD, SEM and XPS have been used. For all exposure times, 316L forms a breakaway type thick oxide scale (rupture of the pre-existing passivating film) with iron oxides on its outer part and a mix of spinels with Fe, Cr and Ni for its inner part. For lower water vapor partial pressure, iron oxides are constituted of wüstite. For higher water vapor partial pressure, iron oxides are constituted of a layer of hematite over a layer of magnetite slightly enriched in chromium. Due to strong oxidation condition, oxide scale is not always homogeneous and iron oxides spallation may occur. For 2.5 min of oxidation on 441, a very thin layer of protective chromium oxide is formed. For longer exposure time, an almost homogeneous and much thicker layer mainly consisting of Cr 2 O 3 is produced. The thickness varies slightly and gradually from 4 to 20 min of oxidation. There are Mn-Cr spinels mixed with the chromium oxide. The most external part is strongly enriched in Mn and Fe in a spinel structure. The diffusivity of chromium is regarded as the main cause of the difference of oxidation behavior. In both cases, the first step is a very thin chromium oxide layer. When the oxidation conditions becomes too strong in terms of exposure time or water vapor partial pressure, this oxide layer breaks. The ferritic steel is able to heal and thicken its protective chromium oxide, preventing the breakaway. The healing would be due to the high diffusivity of chromium. The thickening would be caused by the presence of the Mn-Cr spinels which are a less effective diffusion barrier. The lower diffusivity of chromium in austenite promotes the breakaway
Stellar granulation as seen in disk-integrated intensity

International audienceContext. A large set of stars observed by CoRoT and Kepler shows clear evidence for the presence of a stellar background, which is interpreted to arise from surface convection, i.e., granulation. These observations show that the characteristic time-scale (τeff) and the root-mean-square (rms) brightness fluctuations (σ) associated with the granulation scale as a function of the peak frequency (νmax) of the solar-like oscillations. Aims. We aim at providing a theoretical background to the observed scaling relations based on a model developed in Paper I. Methods. We computed for each 3D model the theoretical power density spectrum (PDS) associated with the granulation as seen in disk-integrated intensity on the basis of the theoretical model published in Paper I. For each PDS we derived the associated characteristic time (τeff) and the rms brightness fluctuations (σ) and compared these theoretical values with the theoretical scaling relations derived from the theoretical model and the measurements made on a large set of Kepler targets. Results. We derive theoretical scaling relations for τeff and σ, which show the same dependence on νmax as the observed scaling relations. In addition, we show that these quantities also scale as a function of the turbulent Mach number (ℳa) estimated at the photosphere. The theoretical scaling relations for τeff and σ match the observations well on a global scale. Quantitatively, the remaining discrepancies with the observations are found to be much smaller than previous theoretical calculations made for red giants. Conclusions. Our modelling provides additional theoretical support for the observed variations of σ and τeff with νmax. It also highlights the important role of ℳa in controlling the properties of the stellar granulation. However, the observations made with Kepler on a wide variety of stars cannot confirm the dependence of our scaling relations on ℳa. Measurements of the granulation background and detections of solar-like oscillations in a statistically sufficient number of cool dwarf stars will be required for confirming the dependence of the theoretical scaling relations with ℳa
Experimental analysis on membrane wrinkling under biaxial load - Comparison with bifurcation analysis

International audienceThis paper presents a detailed experimental study of the formation and evolution of the wrinkle pattern that form in flat elastic and isotropic membranes under the action of in-plane tension. The experiments were carried out on a cruciform specimen stretched along two uncoupled axes using various loading paths. The wrinkled shapes of the membrane were digitized by using a full-field measurement based on the fringe analysis method.Over this experiment, several phenomena were observed: the mechanism of wrinkle division, the influence of the membrane thickness on the wrinkle pattern, and the reproducibility of a kinematic configuration of wrinkles.The main result is that non-unique wrinkle shapes have been observed over repeated experiments for nominally identical boundary conditions. The uncertainty of the experimental wrinkle shape has been explained using comparison with the results of a post-buckling finite element analysis
CO[2] Sequestration by Natural Zeolite for Greenhouse Effect Control

This paper describes the adsorption of CO[2] on pores in natural erionite exchanged with aqueous solutions of Na{+}, Mg{2+}, and Ca{2+} salts at different concentrations, variable time and temperature of treatment. Experimental data of CO[2] adsorption were treated by the Freundlich and Langmuir equations. Complementarily were evaluated standard adsorption energies and the degree of interaction of the gas with the zeolite; the evolution of isosteric heats of adsorption was analyzed. The exchange with Na{+} favors the creation of emergent pores thus causing an increase of the adsorption capacity for CO[2]. The presence of Na{+} at micropore entrances causes an increased adsorption into the nanocavities and on the external area of the ion-exchanged zeolites. The development of nanopores in erionite was evaluated through the Barrett-Joyner-Halenda and NLDFT methods. Depending on the conditions of the exchange treatment, Na{+} was found to be most favorable, well distributed, and accessible for N[2] adsorption
BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib.

Olaparib (AZD-2281, Ku-0059436) is an orally bioavailable and well-tolerated poly(ADP-ribose) polymerase (PARP) inhibitor currently under investigation in patients with solid tumors. To study the clinical potential of olaparib as a single-agent for the treatment of acute myeloid leukemia (AML) patients, we analyzed the in vitro sensitivity of AML cell lines and primary blasts. Clinically achievable concentrations of olaparib were able to induce cell death in the majority of primary AML case samples (88%) and tested cell lines. At these concentrations, olaparib preferentially killed leukemic blasts sparing normal lymphocytes derived from the same patient and did not substantially affect the viability of normal bone marrow and CD34-enriched peripheral blood cells obtained from healthy donors. Most primary AML analyzed were characterized by low BRCA1 mRNA level and undetectable protein expression that likely contributed to explain their sensitivity to olaparib. Noteworthy, while PARP1 over-expression was detected in blasts not responsive to olaparib, phosphorylation of the histone H2AFX (γH2AX) was associated with drug sensitivity. As to genetic features of tested cases the highest sensitivity was shown by a patient carrying a 11q23 deletion. The high sensitivity of AML blasts and the identification of biomarkers potentially able to predict response and/or resistance may foster further investigation of olaparib monotherapy for AML patients unfit to conventional chemotherapy
Measurement of angular correlations in Drell-Yan lepton pairs to probe Z/γ* boson transverse momentum at √s=7 TeV with the ATLAS detector

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMA measurement of angular correlations in Drell–Yan lepton pairs via the φ ∗ η observable is presented. This variable probes the same physics as the Z/γ ∗ boson transverse momentum with a better experimental resolution. The Z/γ ∗ → e+e− and Z/γ ∗ → μ+μ− decays produced in proton–proton collisions at a centre-of-mass energy of √ s = 7 TeV are used. The data were collected with the ATLAS detector at the LHC and correspond to an integrated luminosity of 4.6 fb−1. Normalised differential cross sections as a function of φ ∗ η are measured separately for electron and muon decay channels. These channels are then combined for improved accuracy. The cross section is also measured double differentially as a function of φ ∗ η for three independent bins of the Z boson rapidity. The results are compared to QCD calculations and to predictions from different Monte Carlo event generators. The data are reasonably well described, in all measured Z boson rapidity regions, by resummed QCD predictions combined with fixed-order perturbative QCD calculations or by some Monte Carlo event generators. The measurement precision is typically better by one order of magnitude than present theoretical uncertaintiesWe acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN and the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA) and in the Tier-2 facilities worldwid
Complex hyperbolic Fenchel-Nielsen coordinates.

Let Σ be a closed, orientable surface of genus g. It is known that the  representation variety of π1(Σ) has 2g−3 components of (real) dimension 16g−16 and two components of dimension 8g−6. Of special interest are the totally loxodromic, faithful (that is quasi-Fuchsian) representations. In this paper we give global real analytic coordinates on a subset of the representation variety that contains the quasi-Fuchsian representations. These coordinates are a natural generalisation of Fenchel–Nielsen coordinates on the Teichmüller space of Σ and complex Fenchel–Nielsen coordinates on the (classical) quasi-Fuchsian space of Σ
Multisensory mechanisms of body ownership and self-location

Having an accurate sense of the spatial boundaries of the body is a prerequisite for
interacting with the environment and is thus essential for the survival of any organism with
a central nervous system. Every second, our brain receives a staggering amount of
information from the body across different sensory channels, each of which features a
certain degree of noise. Despite the complexity of the incoming multisensory signals, the
brain manages to construct and maintain a stable representation of our own body and its
spatial relationships to the external environment. This natural “in-body” experience is such
a fundamental subjective feeling that most of us take it for granted. However, patients with
lesions in particular brain areas can experience profound disturbances in their normal sense
of ownership over their body (somatoparaphrenia) or lose the feeling of being located
inside their physical body (out-of-body experiences), suggesting that our “in-body” experience depends on intact neural circuitry in the temporal, frontal, and parietal brain regions.
The question at the heart of this thesis relates to how the brain combines visual, tactile, and
proprioceptive signals to build an internal representation of the bodily self in space.



Over the past two decades, perceptual body illusions have become an important tool for
studying the mechanisms underlying our sense of body ownership and self-location. The
most influential of these illusions is the rubber hand illusion, in which ownership of an
artificial limb is induced via the synchronous stroking of a rubber hand and an individual’s
hidden real hand. Studies of this illusion have shown that multisensory integration within
the peripersonal space is a key mechanism for bodily self-attribution. In Study I, we
showed that the default sense of ownership of one’s real hand, not just the sense of rubber
hand ownership, also depends on spatial and temporal multisensory congruence principles
implemented in fronto-parietal brain regions. In Studies II and III, we characterized two
novel perceptual illusions that provide strong support for the notion that multisensory
integration within the peripersonal space is intimately related to the sense of limb ownership, and we examine the role of vision in this process. In Study IV, we investigated a fullbody version of the rubber hand illusion—the “out-of-body illusion”—and show that it can
be used to induce predictable changes in one’s sense of self-location and body ownership.
Finally, in Study V, we used the out-of-body illusion to “perceptually teleport” participants
during brain imaging and identify activity patterns specific to the sense of self-location in a
given position in space. Together, these findings shed light on the role of multisensory
integration in building the experience of the bodily self in space and provide initial
evidence for how representations of body ownership and self-location interact in the brain
The (K-, p) reaction on nuclei with in-flight kaons

We perform a theoretical study of the spectrum of protons with kinetic energies of around 600 MeV, emitted following the interaction of 1 GeV/c kaons with nuclei. A recent experimental analysis of this (K-,p) reaction on 12C, based on the dominant quasielastic process, has suggested a deeply attractive kaon nucleus potential. Our Monte Carlo simulation considers, in addition, the one-and two-nucleon K- absorption processes producing hyperons that decay into \pi N pairs. We find that this kaon in-flight reaction is not well suited to determine the kaon optical potential due, essentially, to the limited sensitivity of the cross section to its strength, but also to unavoidable uncertainties from the coincidence requirement applied in the experiment. A shallow kaon nucleus optical potential obtained in chiral models is perfectly compatible with the observed spectrum
Synthesis and crystal structure analysis of 2-​(4-​fluorobenzyl)​-​6-​phenylimidazo[2,​1-​b]​- [1,​3,​4]​thiadiazole and its chlorophenyl derivative

Prepns. of 2-​(4-​fluorobenzyl)​-​6-​phenylimidazo[2,​1-​b]​[1,​3,​4]​thiadiazole and its chlorophenyl deriv. were described.  Preliminary anal. was done spectroscopically by means of 1H NMR, 13C NMR spectra, mass spectra and elemental analyses.  Further the structures were confirmed by X-​ray crystal structure analyses.  The 4-​fluorophenyl compd. crystd. in a triclinic P-​1 space group with three independent mols. in the asym. unit, while the 4-​chlorophenyl compd. belonged to P21/c space group with one mol. in the asym. unit.  The imidazo-​thiadiazole entity was as usual planar.  Intramol. C-​H···N hydrogen bonding between the imidazole and the Ph ring of the mol. was obsd. in both compds.  The mols. of 4-​fluorophenyl deriv. was linked into two dimensional supramol. hexagonal hydrogen bonded network sustained by C-​H···F interaction, while those of 4-​chlorophenyl deriv. was linked by bifurcated C-​H···N interactions.  Further, the mol. packing of both the compds. was stabilized by π-​π stacking interactions between the benzene and imidazo-​thiadiazole ring systems
Understanding molecular representations in machine learning: The role of
  uniqueness and target similarity

The predictive accuracy of Machine Learning (ML) models of molecular
properties depends on the choice of the molecular representation. Based on the
postulates of quantum mechanics, we introduce a hierarchy of representations
which meet uniqueness and target similarity criteria. To systematically control
target similarity, we rely on interatomic many body expansions, as implemented
in universal force-fields, including Bonding, Angular, and higher order terms
(BA). Addition of higher order contributions systematically increases
similarity to the true potential energy and predictive accuracy of the
resulting ML models. We report numerical evidence for the performance of BAML
models trained on molecular properties pre-calculated at electron-correlated
and density functional theory level of theory for thousands of small organic
molecules. Properties studied include enthalpies and free energies of
atomization, heatcapacity, zero-point vibrational energies, dipole-moment,
polarizability, HOMO/LUMO energies and gap, ionization potential, electron
affinity, and electronic excitations. After training, BAML predicts energies or
electronic properties of out-of-sample molecules with unprecedented accuracy
and speed
Measurement of the CKM angle $\gamma$ from a combination of LHCb results

A combination of measurements sensitive to the CKM angle $\gamma$ from LHCb
is performed. The inputs are from analyses of time-integrated $B^{+}\rightarrow
DK^+$, $B^{0} \rightarrow D K^{*0}$, $B^{0} \rightarrow D K^+ \pi^-$ and $B^{+}
\rightarrow D K^+\pi^+\pi^-$ tree-level decays. In addition, results from a
time-dependent analysis of $B_{s}^{0} \rightarrow D_{s}^{\mp}K^{\pm}$ decays
are included. The combination yields $\gamma = (72.2^{+6.8}_{-7.3})^\circ$,
where the uncertainty includes systematic effects. The 95.5% confidence level
interval is determined to be $\gamma \in [55.9,85.2]^\circ$. A second
combination is investigated, also including measurements from $B^{+}
\rightarrow D \pi^+$ and $B^{+} \rightarrow D \pi^+\pi^-\pi^+$ decays, which
yields compatible results.Comment: All figures and tables, along with any supplementary material and
  additional information, are available at
  https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-032.htm
Biogeochemistry of “pristine” freshwater stream and lake systems in the western Canadian Arctic.

Climate change poses a substantial threat to the stability of the Arctic terrestrial carbon (C) pool as warmer air temperatures thaw permafrost and deepen the seasonally-thawed active layer of soils and sediments. Enhanced water flow through this layer may accelerate the transport of C and major cations and anions to streams and lakes. These act as important conduits and reactors for dissolved C within the terrestrial C cycle. It is important for studies to consider these processes in small headwater catchments, which have been identified as hotspots of rapid mineralisation of C sourced from ancient permafrost thaw. In order to better understand the role of inland waters in terrestrial C cycling we characterised the biogeochemistry of the freshwater systems in a c. 14 km2 study area in the western Canadian Arctic. Sampling took place during the snow-free seasons of 2013 and 2014 for major inorganic solutes, dissolved organic and inorganic C (DOC and DIC, respectively), carbon dioxide (CO2) and methane (CH4) concentrations from three water type groups: lakes, polygonal pools and streams. These groups displayed differing biogeochemical signatures, indicative of contrasting biogeochemical controls. However, none of the groups showed strong signals of enhanced permafrost thaw during the study seasons. The mean annual air temperature in the region has increased by more than 2.5 °C since 1970, and continued warming will likely affect the aquatic biogeochemistry. This study provides important baseline data for comparison with future studies in a warming Arctic