Move 1 d4 (black to move)
FEN: rnbqkbnr/pppppppp/8/8/3P4/8/PPP1PPPP/RNBQKBNR b KQkq - 0 1
Comment: I'm not terribly familiar with Van Wely's opening preferences or style.

Move 4 Qc2 (black to move)
FEN: rnbqk2r/pppp1ppp/4pn2/8/1bPP4/2N5/PPQ1PPPP/R1B1KBNR b KQkq - 3 4
Comment: White plans a2-a3 to get rid of Bb4 before continuing with his plan to occupy the center with pawns.

Move 7 b6 (white to move)
FEN: rnbq1rk1/p1pp1ppp/1p2pn2/8/2PP4/P1Q5/1P2PPPP/R1B1KBNR w KQ - 0 7
Comment: First he used ...Bb4 and now ...Bb7: all resources to prevent e2-e4, but without weakening more squares by ...d7-d5 (at least not yet) .

Move 8 f3 (black to move)
FEN: rn1q1rk1/pbpp1ppp/1p2pn2/6B1/2PP4/P1Q2P2/1P2P1PP/R3KBNR b KQ - 0 8
Comment: Using this pawn to support e2-e4 weakens Ke1 a tiny bit and gets in the way of Ng1-f3. so, Black often responds with ...d7-d5 when the weakened e5 isn't much of an issue. This is a variation GM Alexei Shirov has played quite a lot in years past (see his book _Fire_on_Board_ for examples) .

Move 9 d6 (white to move)
FEN: rn1q1rk1/pbp2ppp/1p1ppn2/6B1/2PP4/P1Q2P2/1P2P1PP/R3KBNR w KQ - 0 9
Comment: This is dubious because it allows White to occupy the center unhindered and having incurred no significant weaknesses.

Move 9 e4 (black to move)
FEN: rn1q1rk1/pbp2ppp/1p1ppn2/6B1/2PPP3/P1Q2P2/1P4PP/R3KBNR b KQ - 0 9
Comment: threatening e4-e5

Move 10 dxc5 (black to move)
FEN: rn1q1rk1/pb3ppp/1p1ppn2/2P3B1/2P1P3/P1Q2P2/1P4PP/R3KBNR b KQ - 0 10
Comment: This keeps the position somewhat open, though it does give up on using the pawns to squeeze Black to death. Inflicting weaknesses on the opponent is often more valuable than efforts to keep their pieces quiet (restrained) . After this the d-file will be at least partly open, White's Ra1-d1 could be very good and Pe4 will still block Bb7.

Move 12 Nc6 (white to move)
FEN: r2q1rk1/pb3ppp/2nppn2/2p3B1/2P1P3/P1Q2P2/1P4PP/2KR1BNR w - - 2 12
Comment: It looks like Black intends ...e6-e5 and ...Nc6-d4 to block the d-file and to keep White's light-square pawns fixed in place, so Bf1 can't become active.

Move 13 Ne2 (black to move)
FEN: r2q1rk1/pb3p1p/2nppp2/2p5/2P1P3/P1Q2P2/1P2N1PP/2KR1B1R b - - 1 13
Comment: This rather normal-looking development move isn't among Fritz' top candidate moves, favoring instead the peculiar Qc3-d3 or f3-f4.

Move 14 e5 (white to move)
FEN: r2q1rk1/pb3p1p/2np1p2/2p1p3/2P1P3/P1Q2P2/1P2N1PP/2KR1B1R w - - 0 14
Comment: In light of the game continuation one might consider ...Kg8-g7, but without ...e6-e5 and ...Nc6-d4 the pawn at d6 would still be weak.

Move 14 Qd2 (black to move)
FEN: r2q1rk1/pb3p1p/2np1p2/2p1p3/2P1P3/P4P2/1P1QN1PP/2KR1B1R b - - 1 14
Comment: This is a rather obvious attacking move: threatening Qxd6 or Qd2-h6 to get at Kg8. It also has the benefit of clearing c3 to allow Ne2-c3-d5.

Move 15 Nd4 (white to move)
FEN: r2q1rk1/pb3p1p/3p1p2/2p1p3/2PnP3/P4P2/1P1QN1PP/2KR1B1R w - - 2 15
Comment: blocking the threat to Pd6 and incidentally(!) threatening ...Nd4-b3+.

Move 15 Qh6 (black to move)
FEN: r2q1rk1/pb3p1p/3p1p1Q/2p1p3/2PnP3/P4P2/1P2N1PP/2KR1B1R b - - 3 15
Comment: With this there is a potential threat in Rxd4 and then Ne2-g3-f5 or Ng3-h5xf6. Black has to be careful with his king!

Move 16 h4 (black to move)
FEN: r2q1r1k/pb3p1p/3p1p1Q/2p1p3/2PnP2P/P4P2/1P2N1P1/2KR1B1R b - - 0 16
Comment: possibly preparing Rh1-h3-g3; Fritz7 doesn't think highly of this move and "believes" ...Ra8-b8 equalizes.

Move 17 Rb8 (white to move)
FEN: 1r1q1r1k/pb3p1p/3p1p1Q/2p1p3/2PnP2P/P4P2/1P2N1P1/2KR1B1R w - - 1 17
Comment: There is time for offensive moves until Black sees specific threats which must be defended, though it must be said that it wouldn't necessarily be easy for Black to generate an offense from this position.

Move 18 cxd4 (white to move)
FEN: 1r1q1r1k/pb3p1p/3p1p1Q/4p3/2PpP2P/P4P2/1P4P1/2KR1B1R w - - 0 18
Comment: The wall of pawns from f7, f6, e5 and d4 prevents Black's pieces from sitting on the central or queen-side files while defending Kh8.

Move 18 Rd2 (black to move)
FEN: 1r1q1r1k/pb3p1p/3p1p1Q/4p3/2PpP2P/P4P2/1P1R2P1/2K2B1R b - - 1 18
Comment: White keeps his king safe and uncovers Bf1. He might continue with Bf1-e2, Kc1-b1, Rh1-c1 if he needs a fortress. Offensively the plan isn't as obvious. From White's perspective it's good that Black has several weak pawns, but most of White's pieces will have to join in the offense at some point if he's to win.

Move 19 h5 (black to move)
FEN: 1r1q2rk/pb3p1p/3p1p1Q/4p2P/2PpP3/P4P2/1P1R2P1/2K2B1R b - - 0 19
Comment: I'd guess this was a prepared line with Ph5 intended to prevent ...Rg8-g6 and keeping Qh6 firmly in place to threaten Pf6.

Move 23 Qe7 (white to move)
FEN: 6rk/p3qp1p/b2p1p1Q/4p2P/2PpP3/Pr1B1P2/1PR3P1/2KR4 w - - 7 23
Comment: It's difficult for Black to generate any offense when his king's position is weakened this way.

Move 26 Rcb8 (white to move)
FEN: 1r5k/p4p1p/b2pqp1Q/4p2P/2PpP3/Pr1B1P2/1PR3P1/1K1R4 w - - 13 26
Comment: threatening ...Rb3xa3

Move 28 Rg2 (black to move)
FEN: 1rb4k/p3qp1p/3p1p1Q/4p2P/2PpP1P1/Pr1B1P2/1P4R1/K2R4 b - - 2 28
Comment: He appears to be planning g4-g5-g6 or g4-g5xf6, keeping his offensive threats alive.

Move 31 Rdf2 (black to move)
FEN: 6rk/p2bqp1p/1r1p1p1Q/4p2P/2PpP1P1/P2B1P2/KP3RR1/8 b - - 8 31
Comment: It could be said White's pieces are a little better because they have this lateral mobility and can defend at b2 as well as play offense on the f- and g-files. But, how does one use those rooks offensively? There are too many pawns in front of them.

Move 35 Rbb8 (white to move)
FEN: 1r4rk/p3qp1p/3pbp1Q/4p2P/2PpP1P1/PP1B1P2/K5R1/6R1 w - - 3 35
Comment: White gets the first shot at offense and it's largely due to his queen being better than Black's, and that relates to White's king being safer than Black's.

Move 37 fxg5 (white to move)
FEN: 1r4rk/p2bqp1p/3p3Q/4p1pP/2PpPP2/PP1B4/K5R1/6R1 w - - 0 37
Comment: Fritz7; Black gets rid of one weak pawn, but White's advancing pawns are very hard to stop. At least Bd3 is kept quiet by leaving Pe4 in front of it.

Move 38 Qf6 (black to move)
FEN: 1r5k/p2bqprp/3p1Q2/4p1PP/2PpP3/PP1B4/K5R1/6R1 b - - 2 38
Comment: threatening Qxe7 (obviously) and h5-h6 to win Rg7 or mate

Move 41 b4 (black to move)
FEN: 1r5k/p2b1p2/3p1P1p/4p2P/1PPpP3/P2B4/K5R1/8 b - - 0 41
Comment: Fritz7 prefers Rg2-g7 or Ka2-b2.

Move 43 b5 (black to move)
FEN: 6k1/p2b1p2/3p1P1p/1P2p2P/2PpP3/P2B4/K7/8 b - - 0 43
Comment: Fritz7 prefers Ka2-b3. White's a- and b-file pawns are marching forward!

Move 46 Ke8 (white to move)
FEN: 4k3/p4p2/3p1P1p/PP2p2P/2PpP1b1/3B4/K7/8 w - - 1 46
Comment: This is a crucial position to calculate correctly. Are White's pawns advanced enough to force through? If Black has to retreat his bishop then Ph5 remains invulnerable and White has time to bring up his king to play c4-c5 and break through on dark squares.

Move 46 a6 (black to move)
FEN: 4k3/p4p2/P2p1P1p/1P2p2P/2PpP1b1/3B4/K7/8 b - - 0 46
Comment: After this move the Fritz7 evaluation bounces around for a while, but after about 15 ply it jumps to +-.

Move 48 c5 (black to move)
FEN: 3k4/p2b1p2/PP1p1P1p/2P1p2P/3pP3/3B4/K7/8 b - - 0 48
Comment: After this Fritz7 sees it as massively advantageous to White. It's time for Black to resign.

Move 49 Bc4 (black to move)
FEN: 3k4/p2b1p2/PP3P1p/2p1p2P/2BpP3/8/K7/8 b - - 1 49
Comment: Black's bishop and king are overworked defending against bxa7, b6-b7-b8 or Bxf7. This was an impressive and really simple-looking game for Loek "King" Van Wely, especially considering that it's a victory against the reigning "Classical World Champion". I'd guess his home preparation was very much in use and that Kramnik wishes he hadn't played 8...d6 when he could've played 8...d5.