abstract_id
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class label 5
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177k
| embedding_all-mpnet-base-v2
sequence | embedding_multi-qa-mpnet-base-dot-v1
sequence | embedding_all-MiniLM-L12-v2
sequence |
|---|---|---|---|---|---|---|---|
24672940 | 2methods
| The treatment period for the two groups was @ weeks . | 3 | 800 | [
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24672940 | 2methods
| Patients were followed-up till the @th week . | 4 | 801 | [
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24672940 | 2methods
| Clinical symptoms such as fever , lymphadenopathy and hepatosplenomegaly , as well as lab indices such as abnormal lymphocyte percentage , EB virus antibody , virus DNA load , T cell subsets , immunoglobulin , and so on were observed before and after treatment , at week @ and @ of follow-ups . | 5 | 802 | [
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] |
24672940 | 4results
| ( @ ) The total effective rate at week @ was @ % in the treatment group , higher than that of the control group ( @ % ) , but there was no statistical difference between the two groups . | 6 | 803 | [
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] |
24672940 | 4results
| ( @ ) The time for defervescence , duration of pharyngeal hyperemia , duration of swollen tonsils was shorter in the treatment group than in the control group ( P < @ ) . | 7 | 804 | [
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] |
24672940 | 4results
| The subsidence of lymphadenopathy , hepatomegaly , and abnormal lymphocytes was better in the treatment group than in the control group ( P < @ ) . | 8 | 805 | [
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] |
24672940 | 4results
| ( @ ) The positive cases of peripheral blood hetero-lymphocyte was significantly reduced after treatment , at week @ and @ of follow-ups both in the treatment group and the control group ( P < @ ) . | 9 | 806 | [
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24672940 | 4results
| The expression of IgA and IgM decreased after treatment in the two groups when compared with before treatment in the same group ( P < @ , P < @ ) . | 10 | 807 | [
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24672940 | 4results
| IgG in the treatment group also obviously decreased after treatment , at week @ and @ of follow-ups ( P < @ , P < @ ) , while it decreased only after treatment in the control group ( P < @ ) . | 11 | 808 | [
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] |
24672940 | 4results
| Activities of AST and ALT in the treatment group and the AST activity in the control group were markedly improved when compared with those before treatment ( P < @ ) . | 12 | 809 | [
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] |
24672940 | 4results
| Compared with the control group , the abnormal lymphocyte positive case number obviously decreased in the treatment group after treatment , at week @ and @ of follow-ups ( P < @ ) . | 13 | 810 | [
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] |
24672940 | 4results
| ( @ ) After treatment , at week @ and @ of follow-ups , CD@ + and CD@ + significantly decreased ; CD@ + , CD@/CD@ , and B cells significantly increased in the two groups , when compared with before treatment ( P < @ ) . | 14 | 811 | [
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] |
24672940 | 4results
| NK cells significantly increased more in the treatment group after treatment , at week @ and @ of follow-ups , higher than before treatment as well as the control group ( P < @ ) . | 15 | 812 | [
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] |
24672940 | 4results
| ( @ ) EB viral DNA and EB viral CA-IgM negative conversion case numbers significantly increased in the two groups after treatment , at week @ and @ of follow-ups ( P < @ ) . | 16 | 813 | [
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] |
24672940 | 4results
| Compared with the control group , EB viral DNA and EB viral CA-IgM negative conversion case numbers significantly increased in the treatment group after treatment and at week @ of follow-ups ( P < @ ) . | 17 | 814 | [
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24672940 | 1conclusions
| Treatment of EB virus infection by Chinese medical treatment was effective . | 18 | 815 | [
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24672940 | 1conclusions
| It could promote the recovery of EB viral infection , and reduce the risk of vicious disease after EB viral infection . | 19 | 816 | [
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25039547 | 3objective
| The primary objective was to compare the cosmetic outcomes of traumatic trunk and extremity lacerations repaired using absorbable versus nonabsorbable sutures . | 0 | 817 | [
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25039547 | 3objective
| The secondary objective was to compare complication rates between the two groups . | 1 | 818 | [
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25039547 | 2methods
| This was a randomized controlled trial comparing wounds repaired with Vicryl Rapide and Prolene sutures . | 2 | 819 | [
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25039547 | 2methods
| Pediatric and adult patients with lacerations were enrolled in the study . | 3 | 820 | [
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25039547 | 2methods
| At a @-day follow-up , the wounds were evaluated for infection and dehiscence . | 4 | 821 | [
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25039547 | 2methods
| After @ months , patients returned to have the wounds photographed . | 5 | 822 | [
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25039547 | 2methods
| Two plastic surgeons blinded to the method of closure rated the cosmetic outcome of each wound using a @-mm visual analog scale ( VAS ) . | 6 | 823 | [
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25039547 | 2methods
| Using a noninferiority design , a VAS score of @ mm or greater was considered to be a clinically significant difference . | 7 | 824 | [
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] |
25039547 | 2methods
| We used a Student 's t-test to compare differences between mean VAS scores and odds ratios ( ORs ) to compare differences in complication rates between the two groups . | 8 | 825 | [
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] |
25039547 | 4results
| Of the @ patients enrolled , @ completed the study including @ in the Vicryl Rapide group and @ in the Prolene group . | 9 | 826 | [
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25039547 | 4results
| The mean ( SD ) age of patients who completed the study was @ ( @ ) years , and @ were male . | 10 | 827 | [
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] |
25039547 | 4results
| We found no significant differences in the age , race , sex , length of wound , number of sutures , or layers of repair in the two groups . | 11 | 828 | [
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] |
25039547 | 4results
| The observer 's mean VAS for the Vicryl Rapide group was @ mm ( @ % confidence interval -LSB- CI -RSB- = @ to @ mm ) and for the Prolene group was @ mm ( @ % CI = @ to @ mm ) . | 12 | 829 | [
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] |
25039547 | 4results
| The resulting mean difference was @ mm ( @ % CI = -@ to @ mm ; p = @ ) ; thus noninferiority was established . | 13 | 830 | [
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] |
25039547 | 4results
| Statistical testing showed no differences in the rates of complications between the two groups , but a higher percentage of the Vicryl Rapide wounds developed complications . | 14 | 831 | [
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25039547 | 1conclusions
| The use of absorbable sutures for the repair of simple lacerations on the trunk and extremities should be considered as an alternative to nonabsorbable suture repair . | 15 | 832 | [
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25139873 | 3objective
| Aspirin early after intravenous thrombolysis in acute ischemic stroke increases the risk of symptomatic intracranial hemorrhage ( SICH ) , without influencing functional outcome at @ months . | 0 | 833 | [
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25139873 | 3objective
| The effect of aspirin on early neurological deterioration ( END ) was explored as a post hoc analysis of the randomized Antiplatelet Therapy in Combination With Recombinant t-PA Thrombolysis in Ischemic Stroke ( ARTIS ) trial . | 1 | 834 | [
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25139873 | 2methods
| END , defined as a @ points National Institutes of Health Stroke Scale worsening @ hours after intravenous thrombolysis , was categorized into SICH ( ENDSICH ) and cerebral ischemia ( ENDCI ) . | 2 | 835 | [
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25139873 | 2methods
| Multinomial logistic regression was used to assess the effect of aspirin on END . | 3 | 836 | [
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25139873 | 4results
| Of the @ patients , @ patients ( @ % ) experienced END ( @ ENDSICH , @ ENDCI ) . | 4 | 837 | [
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25139873 | 4results
| Aspirin increased the risk of ENDSICH ( odds ratio , @ ; @ % confidence interval , @-@ @ ) but not of ENDCI ( odds ratio , @ ; @ % confidence interval , @-@ @ ) . | 5 | 838 | [
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] |
25139873 | 4results
| After adjustment for other explanatory variables , the association between aspirin and ENDSICH remained significant . | 6 | 839 | [
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] |
25139873 | 1conclusions
| In this trial , there is no evidence of an early antithrombotic effect from the addition of aspirin to intravenous thrombolysis in acute ischemic stroke . | 7 | 840 | [
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] |
24917273 | 3objective
| To compare the relative effectiveness of methotrexate and mycophenolate mofetil for noninfectious intermediate uveitis , posterior uveitis , or panuveitis . | 0 | 841 | [
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24917273 | 2methods
| Multicenter , block-randomized , observer-masked clinical trial . | 1 | 842 | [
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24917273 | 2methods
| Eighty patients with noninfectious intermediate , posterior , or panuveitis requiring corticosteroid-sparing therapy at Aravind Eye Hospitals in Madurai and Coimbatore , India . | 2 | 843 | [
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] |
24917273 | 2methods
| Patients were randomized to receive @ mg weekly oral methotrexate or @ g twice daily oral mycophenolate mofetil and were monitored monthly for @ months . | 3 | 844 | [
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24917273 | 2methods
| Oral prednisone and topical corticosteroids were tapered . | 4 | 845 | [
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] |
24917273 | 2methods
| Masked examiners assessed the primary outcome of treatment success , defined by achieving the following at @ and @ months : ( @ ) @ + anterior chamber cells , @ + vitreous cells , @ + vitreous haze and no active retinal/choroidal lesions in both eyes , ( @ ) @ mg of prednisone and @ drops of prednisolone acetate @ % a day , and ( @ ) no declaration of treatment failure because of intolerability or safety . | 5 | 846 | [
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] |
24917273 | 2methods
| Additional outcomes included time to sustained corticosteroid-sparing control of inflammation , change in best spectacle-corrected visual acuity , resolution of macular edema , adverse events , subgroup analysis by anatomic location , and medication adherence . | 6 | 847 | [
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24917273 | 4results
| Forty-one patients were randomized to methotrexate and @ to mycophenolate mofetil . | 7 | 848 | [
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] |
24917273 | 4results
| A total of @ patients ( @ methotrexate , @ mycophenolate mofetil ) contributed to the primary outcome . | 8 | 849 | [
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24917273 | 4results
| Sixty-nine percent of patients achieved treatment success with methotrexate and @ % with mycophenolate mofetil ( P = @ ) . | 9 | 850 | [
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] |
24917273 | 4results
| Treatment failure from adverse events or tolerability was not different by treatment arm ( P = @ ) . | 10 | 851 | [
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] |
24917273 | 4results
| There were no differences between treatment groups in time to corticosteroid-sparing control of inflammation ( P = @ ) , change in best spectacle-corrected visual acuity ( P = @ ) , or resolution of macular edema ( P = @ ) . | 11 | 852 | [
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24917273 | 1conclusions
| There was no statistically significant difference in corticosteroid-sparing control of inflammation between patients receiving methotrexate or mycophenolate mofetil . | 12 | 853 | [
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24917273 | 1conclusions
| However , there was a @ % difference in treatment success favoring methotrexate . | 13 | 854 | [
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24925006 | 0background
| The prevalence of methicillin-resistant Staphylococcus aureus ( MRSA ) respiratory infection in cystic fibrosis ( CF ) has increased dramatically over the last decade , and is now affecting approximately @ % of patients . | 0 | 855 | [
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24925006 | 0background
| Epidemiologic evidence suggests that persistent infection with MRSA results in an increased rate of decline in FEV@ and shortened survival . | 1 | 856 | [
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24925006 | 0background
| Currently , there are no conclusive studies demonstrating an effective and safe treatment protocol for persistent MRSA respiratory infection in CF. | 2 | 857 | [
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24925006 | 2methods
| The primary objective of this study is to evaluate the safety and efficacy of a @-day course of vancomycin for inhalation in combination with oral antibiotics in eliminating MRSA from the respiratory tract of individuals with CF and persistent MRSA infection . | 3 | 858 | [
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24925006 | 2methods
| This is a two-center , randomized , double-blind , comparator-controlled , parallel-group study with @:@ assignment to either vancomycin for inhalation ( @mg twice a day ) or taste-matched placebo for @days in individuals with cystic fibrosis . | 4 | 859 | [
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24925006 | 2methods
| In addition , both groups will receive oral rifampin , a second oral antibiotic - trimethoprim/sulfamethoxazole ( TMP/SMX ) or doxycycline , protocol determined - mupirocin intranasal cream , and chlorhexidine body washes . | 5 | 860 | [
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24925006 | 2methods
| Forty patients with persistent respiratory tract MRSA infection will be enrolled : @ will be randomized to vancomycin for inhalation and @ to a taste-matched placebo . | 6 | 861 | [
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24925006 | 2methods
| The primary outcome will be the presence of MRSA in sputum respiratory tract cultures @month after the conclusion of treatment . | 7 | 862 | [
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24925006 | 2methods
| Secondary outcomes include the efficacy of the intervention on : FEV@ % predicted , patient reported outcomes , pulmonary exacerbations , and MRSA colony-forming units found in respiratory tract sample culture . | 8 | 863 | [
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24925006 | 1conclusions
| Results of this study will provide guidance to clinicians regarding the safety and effectiveness of a targeted eradication strategy for persistent MRSA infection in CF. | 9 | 864 | [
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24559194 | 0background
| There is a strong association between weight gain and metabolic events in patients with schizophrenia receiving many of the second-generation antipsychotic agents . | 0 | 865 | [
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24559194 | 0background
| We explored the relationship between body mass index ( BMI ) and metabolic events in patients with schizophrenia receiving long-acting injectable paliperidone palmitate ( PP ) in a long-term trial . | 1 | 866 | [
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24559194 | 2methods
| We conducted a post hoc analysis of data from a PP study that included a @-week open-label transition ( TR ) and maintenance phase ; a variable duration , randomized , double-blind ( DB ) , placebo-controlled phase and a @-week open-label extension ( OLE ) phase . | 2 | 867 | [
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24559194 | 2methods
| Overall , @ patients received PP continuously from study entry through discontinuation or study completion and were grouped by baseline BMI ( kg/m@ ) : underweight ( BMI < @ ; n = @ , @ % ) , normal-weight ( BMI @ - < @ ; n = @ , @ % ) , overweight ( BMI @ - < @ ; n = @ , @ % ) and obese ( BMI @ ; n = @ , @ % ) . | 3 | 868 | [
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24559194 | 2methods
| Metabolic treatment-emergent adverse events ( TEAEs ) and changes in related laboratory results from TR baseline were analyzed . | 4 | 869 | [
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] |
24559194 | 4results
| PP exposure was similar across BMI groups ; overall mean ( SD ) dose/month was @ ( @ ) mg eq . | 5 | 870 | [
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24559194 | 4results
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24559194 | 4results
| Occurrences of metabolic TEAEs overall by group were @ % ( underweight ) , @ % ( normal-weight ) , @ % ( overweight ) , and @ % ( obese ) . | 7 | 872 | [
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24559194 | 4results
| The most common ( @ % ) metabolic TEAE were weight gain and elevated blood levels of glucose , lipids , and insulin . | 8 | 873 | [
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24559194 | 4results
| Mean BMI and weight increased in normal-weight and overweight groups at DB endpoint , and in underweight , normal-weight and overweight groups at OLE endpoint ( p @ ) . | 9 | 874 | [
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24559194 | 4results
| No consistent trend for increased metabolic-related laboratory values by baseline BMI group was observed . | 10 | 875 | [
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24559194 | 4results
| Homeostatic model assessments for insulin resistance indicated preexisting insulin resistance at baseline , with minimal changes at OLE endpoint across baseline BMI groups . | 11 | 876 | [
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24559194 | 1conclusions
| Occurrences of metabolic-related TEAEs trended with greater BMI status in patients with schizophrenia treated with PP ; consistent trends in metabolic-related laboratory values were not observed . | 12 | 877 | [
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25203483 | 0background
| Fecal immunochemical tests ( FITs ) are recommended to screen average-risk adults for colorectal cancer ( CRC ) . | 0 | 878 | [
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25203483 | 0background
| Little research has examined whether a two-sample FIT affects participant uptake , compared with a one-sample FIT . | 1 | 879 | [
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25203483 | 0background
| Examining participant uptake is important , as evidence suggests that a two-sample FIT may increase the sensitivity to detect CRC . | 2 | 880 | [
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25203483 | 3objective
| This study had two objectives : ( i ) to evaluate FIT completion in a population that received either a one-sample FIT kit ( @-FIT ) or a two-sample FIT kit ( @-FIT ) and ( ii ) to understand whether uptake varies by age , sex , or receipt of prior CRC screening . | 3 | 881 | [
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] |
25203483 | 2methods
| We conducted a randomized controlled trial in which @ participants who were aged between @ and @ years and were at an average risk for CRC , and who had requested FITs , randomly received @-FIT ( n = @ ) or @-FIT ( n = @ ) kits . | 4 | 882 | [
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] |
25203483 | 2methods
| FIT completion was defined as the completion and return of a one-sample test by the patients in the @-FIT group or of both sample tests by those in the @-FIT group . | 5 | 883 | [
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] |
25203483 | 2methods
| Cox proportional hazard regression models were used to determine the independent effect of group type ( @-FIT vs. @-FIT ) on the completion of the FIT , adjusting for age , sex , and receipt of prior CRC screening . | 6 | 884 | [
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] |
25203483 | 4results
| The @-FIT group had lower test completion rates ( hazard ratio = @ ; @ % confidence interval = @-@ @ ; P = @ ) after adjusting for age , sex , and receipt of prior CRC screening . | 7 | 885 | [
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] |
25203483 | 4results
| Participant uptake did not vary by age , sex , or receipt of prior CRC screening . | 8 | 886 | [
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25203483 | 1conclusions
| This unique , rigorous randomized controlled trial found that the @-FIT regimen decreases completion of FIT . | 9 | 887 | [
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25203483 | 1conclusions
| Further research is needed to understand whether decreases in participant uptake are offset by increased gains in test sensitivity . | 10 | 888 | [
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25227656 | 3objective
| Evaluation of the safety and efficacy of pazopanib , a multikinase angiogenesis inhibitor , in a single-arm , open-label , extension study ( VEG@/NCT@ ) for placebo-treated patients with advanced renal cell carcinoma ( RCC ) from a randomized , double-blind , placebo-controlled phase III study ( VEG@/NCT@ ) . | 0 | 889 | [
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25227656 | 2methods
| Patients received pazopanib @ mg/day . | 1 | 890 | [
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25227656 | 2methods
| The primary endpoint was the safety and tolerability of pazopanib treatment . | 2 | 891 | [
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25227656 | 2methods
| Secondary endpoints included response rate per Response Evaluation Criteria in Solid Tumors , progression-free survival ( PFS ) , and overall survival ( OS ) . | 3 | 892 | [
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25227656 | 4results
| Seventy-nine placebo-treated patients from VEG@/NCT@ who experienced disease progression and one pazopanib-treated patient ( an exemption ) were enrolled . | 4 | 893 | [
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25227656 | 4results
| Forty-one patients ( @ % ) were treatment-naive ; @ ( @ % ) were cytokine-pretreated . | 5 | 894 | [
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25227656 | 4results
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25227656 | 4results
| All patients had discontinued pazopanib at the time of analysis . | 7 | 896 | [
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25227656 | 4results
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25227656 | 4results
| The most common adverse events were hypertension ( @ % ) , diarrhea ( @ % ) , hair color changes ( @ % ) , anorexia ( @ % ) , and nausea ( @ % ) . | 9 | 898 | [
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] |
25227656 | 4results
| The response rate was @ % -LSB- @ % confidence interval ( CI ) : @-@ @ -RSB- ; median PFS was @ months ( @ % CI : @-@ @ ) ; median OS was @ months ( @ % CI : @-@ @ ) . | 10 | 899 | [
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