En rekke kjente personer spilte gjesteroller i serien, inkludert Charlton Heston, Grace Kelly, Jack Lemmon, Angela Lansbury, James Dean, Esther Williams, Peter Lorre, Anne Bancroft, Boris Karloff, Fredric March, Basil Rathbone, Mary Astor, Celeste Holm, Walter Matthau, Veronica Lake, Ronald Reagan, Gene Barry, Jeanette MacDonald, Dayton Lummis, Karen Sharpe, Jack Lord, Joanne Woodward, Maureen O'Sullivan, David Janssen, Franchot Tone, Ann Sheridan, Jayne Mansfield, Scott Brady, Martin Huston, Janet Gaynor, Ruth Hussey, Karen Steele, Teresa Wright, Joan Blondell, Beverly Washburn, June Lockhart, Miriam Hopkins, Sylvia Sidney, Nelson Eddy, Vincent Price, Melvyn Douglas og Luise Rainer.