En rekke kjente skuespillere spilte gjesteroller i serien, inkludert James Cagney, John Wayne, Spencer Tracy, Katharine Hepburn, Laurence Olivier, Bob Hope, Barbara Stanwyck, Cary Grant, Lauren Bacall, Humphrey Bogart, Bing Crosby, Elizabeth Taylor, James Stewart, Hedy Lamarr, Joan Crawford, Carole Lombard, Fredric March, Ingrid Bergman, Judy Garland, Ronald Colman, Tyrone Power, Irene Dunne, Orson Welles, Frank Sinatra, Shirley Temple, Betty Grable, Deanna Durbin, Henry Fonda, Wallace Beery, Jeanette MacDonald, Lana Turner, William Holden, Mickey Rooney, Robert Taylor, Rita Hayworth, Robert Mitchum, Betty Hutton, Paul Muni, Ginger Rogers, Gene Kelly, Gloria Swanson, Bette Davis og Edward G. Robinson.