En rekke større byer ligger langs eller tett innved Chiang Jiang: Yibin, Panzhihua, Luzhou, Chongqing, Yichang, Jingzhou, Shishou, Yueyang, Xianning, Wuhan, Ezhou, Huangshi, Huanggang, Chizhou, Jiujiang, Anqing, Tongling, Wuhu, Hefei, Chuzhou, Ma'anshan, Taizhou, Yangzhou, Zhenjiang, Nanjing, Nantong og Shanghai.