Products Accessories QChips Qube 384 QPlates QPatch Knowledge center Applications Service and support News and events ICMS About us IMPROVING THE BENCHMARK FOR CARDIAC SAFETY QPatch A barcode scanner on the gripper arm and stacking of plates on the work plane provides faster and more robust automation. Automated patch clamp made easy. We have designed QPatch II to overcome the constant pressure to increase lab efficiency while maintaining medium and high throughput and high data quality. QPatch II truly is automated patch clamp made easy. The new intuitive software interface ensures fast training and onboarding, which helps reduce human errors and enables staff rotation in the laboratory. The faster control software and new hardware design deliver robust unattended operation so that you can meet the demands of a modern and up-to-date ion channel laboratory. Meet tomorrows demands today The new user interface enables untrained personnel to learn how to operate QPatch II in less than 10 minutes. New and better control software gives a faster and more precise unattended operation, meeting demanding timelines. The new instrument design provides a reduced cell consumption, smaller footprint, a simplified work plane and improved modules for cell handling and QPlate positioning, all to further improve assay quality and instrument robustness. New software features such as online adaptive V½ estimation, predefined standard protocols (e.g. CIPA) and the possibility to run or re-run directly from the system without any setup steps. The temperature control regulates the measurement site temperature during your assay, which means standardized temperature settings for every assay performed. Integration – standardised export formats for Genedata and FDA No seal enhancing agents, individual pipetting and individual control of pressure system is still the hallmark of the QPatch operation, ensuring that experiments perform as close to physiological conditions as possible and that all wells are handled individually. The closest you can get to manual patch clamping. Built on a solid foundation Sophion QPatch has been the benchmark automated patch clamp solution for cardiac safety since 2005. We thought it was time to raise the bar. However, to ensure concordance to historical data, we have provided: Full correlation between QPatch II and QPatch 1:1 protocol transfer from QPatch to QPatch II While the old virtues of QPatch persist True gigaseals without additives, no seal enhancer needed here High reproducibility – full automation from cell handling to analysis Glass flow channels minimize adsorption of compounds and ensure a complete exchange of compounds Intelligent whole-cell formation. All the wells are handled individually Dual electrode per well eliminates maintenance and electrode drift Current clamp and voltage clamp Single- and multi-hole measurements Applicable for cell lines, primary cells and stem cells Single- and multi-hole QPlates available 16 or 48 channels QPatch II – designed to handle the needs of the modern ion channel lab Read more about the QPatch Request pricing Contact Related products Temperature control for QPatch II Current Clamp for QPatch QPatch II Commander Rs Compensation QPatch QPlates QPlate 48 QPlate 48X See more Applications area Biophysical and pharmacological profiling of multiple voltage-gated sodium channel subtypes on QPatch II CiPA hERG Milnes kinetic assay on QPatch Optimization of Cardiac CiPA Targets (hCav1.2 and hKCNQ1/hminK) on the QPatch HT Automated System CiPA – Comprehensive In Vitro Proarrhythmia Assay Nav1.5(Late) cardiac safety assay on QPatch Diseased and control hIPSC motor neurons measured on Qube and QPatch Voltage and current clamp recordings of Cor.4U® human iPS cell-derived cardiomyocytes using Sophion’s QPatch Activities for Optimizing CiPA Recommended Protocols in Patch-Clamp Assay Sophion Bioscience A/S Tel: +45 44 60 88 00 Email: info@sophion.com Follow us: LinkedInTwitter Certification CiPA ISO 9001