Qui som Projectes BRN Seminars Simpòsiums Recercadors DONATE CATALAN COPD VENTILATION REGISTER (CATCOVER) CATALAN COPD VENTILATION REGISTER (CATCOVER) [content_box icon=”bookmark-o” title=”Research team”] Dr. Joan Escarrabill (PRINCIPAL INVESTIGATOR) Hospital Clínic / PDMAR /REDISSEC Dra. Ana Córdoba Hospital Universitari de Bellvitge Dra. Ana Balañá Hospital del Mar Dra. Paola Carmona Hospital Arnau de Vilanova Dr. Antonio Antón Hospital de la Santa Creu i Sant Pau Dr. Manel Luján Hospital Parc Taulí Dra. Eva Farrero Hospital de Bellvitge Dra. Juana Martínez Llorens Hospital del Mar Dr. Sergi Martí Hospital Vall d’Hebron Dra. Cristina Embid Hospital Clínic Dra. Julia Tárrega Hospital de Granollers Dra. Mireia Espallargues AQuAS / REDISSEC Dr. Ramon Farré Barcelona University / IDIBAPS / CIBERES [/content_box] [content_box icon=”bookmark-o” title=”Abstract”] Chronic Obstructive Pulmonary Disease (COPD) is the fourth cause of death in the world. Several descriptive studies suggest that home mechanical ventilation (HMV) improves survival and quality of life of hypercapnic COPD patients. Randomized Controlled Trials (RCT) both are logistically complex and have well-known generalizability limitations. Despite the lack of conclusive evidence, the number of COPD patients on HMV is increasing in most countries. Thus, a different strategy is needed to assess the potential benefits of HMV. This project hypothesizes that the multidisciplinary involvement of clinicians, healthcare authorities (through AQuAS), industry and patients will allow to gather comprehensive information of all stakeholders in a single database (“curated database of COPD patients on HMV”), with around 500 COPD patients in Catalonia, in order to: a) describe their clinical course (prospective observational study), b) find subgroups of patients (clusters) with shared characteristics and c) interrogate the curated database using a cohort multiple randomized controlled trial design (cmRCT), which allows the design of RCTs in specific subgroups of patients in whom complete information is available, so recruitment will be short and easy. The investigation of the potential benefits of high pressure ventilator settings would be a cmRCT prototype. Patient perspective will be considered since the beginning of the study. This novel research strategy will provide useful information for both patient care and design of health care services. [/content_box] [content_box icon=”bookmark-o” title=”Financial suport”] [/content_box] Copyright © 2021 Fundació Barcelona Respiratory Network C/ Bruc, 65, 4t, 3a, 08009 Barcelona NIF: G65893091 Inscrita en el Registre de Fundacions de la Generalitat de Catalunya. Nº 2.791. Telf. 93 633 89 15 / info@brn.cat / www.brn.cat Choose your language