NEWS Quotient Sciences Announces Multimillion-Pound Investment in Drug Substance Manufacturing Facility Read article Drug Substance Quotient Sciences provides drug substance synthesis and manufacturing capabilities from candidate selection through to commercial production. With tactical deployment of best-in-class technologies, we minimize chemistry costs and move your drug substance supply off the critical path. GMP & non-GMP manufacturing Our facilities can provide both GMP and non-GMP drug substance manufacturing with the ability to generate kg per day quantities. Current capabilities include: 5 L GMP and non GMP process chemistry facilities with full thermal control 20 L GMP state of the art reactor streams housed in dedicated walk in fume cupboards with operating temperatures from -90°C up to +180°C. Full integration of reactor stream data logging to a dedicated server, enabling GMP monitoring of all key reaction parameters (pressure, temperature etc.) and real time process optimization. State of the art dedicated material storage area enabling safe storage of a range of chemical classes and segregation of quarantine and released materials. Flexible continuous manufacturing units (Flowsyn, Trickle Bed and Salamander reactors with pressure capabilities up to 50 Bar and operating temperatures up to 180 °C). These equipment trains have the capacity to generate kilogram quantities of materials per day. Automated parallel reactor streams with ReactIR and integrated calorimetry (HFCAL) and offgassing measurement capability Onsite 100L reactors, fully operational in 2021 A range of isolation and drying options, including mobile filter dryers (316 Stainless Steel and Hastelloy MOC) with up to 15 kilogram capacities. Containment systems for handling compounds up to and including Safebridge Band 3. Science / Agility / Culture What makes Quotient Sciences unique? Find out more About Quotient Sciences Quotient Sciences is a drug development and manufacturing accelerator providing integrated programs and tailored services across the entire development pathway. Cutting through silos across a range of drug development capabilities, we save precious time and money in getting drugs to patients. Everything we do for our customers is driven by an unswerving belief that ideas need to become solutions, molecules need to become cures, fast. Because humanity needs solutions, fast. Follow us LinkedIn Twitter Facebook Contact us Quotient Sciences UK +44 (0)115 974 9000 US +1 800 769 3518 Get in touch Copyright © Quotient Sciences 2021 Policies, Statements and Terms of Use Suppliers We use cookies to help us to improve our site and enables us to the best possible service and customer experience. By clicking accept you are agreeing to let us share your data with select third parties for analytics and marketing purposes. Decline Accept