Log in Contact imprint DE EN Translation research Institutes About TWINCORE Events Info desk Career Teaching Career Job postings Job postings Please send your application by email or post. No news in this list. Job postings training Your contact person: Jana Henkel Administration TWINCORE, Center for Experimental and Clinical Infection Research Feodor-Lynen-Str. 7 30625 Hanover Tel: 0511-220027-141 Fax: 0511-220027-148 jana.henkel (at) twincore.de TWINCORE is a joint facility of: © 2015 TWINCORE

Log in Contact imprint DE EN Translation research Institutes About TWINCORE Events Info desk Career Teaching research Research fields New pathogen inhibition mechanisms New pathogen inhibition mechanisms In the past few decades, science has made important breakthroughs in defense against viruses. In the meantime, substances are no longer only available against bacteria, but also against viruses - but by no means in terms of breadth and effectiveness. Our scientists at TWINCORE are looking for new approaches to inhibit the multiplication of viruses in their host. In cooperation with the HZI and the University of Hanover, biological substance libraries are examined for substances with antiviral and bacterial effects. Our scientists carry out these tests using new, in-house developed cell culture methods. One example is the search for inhibitors of hepatitis C virus (HCV) replication. Another focus of our scientists: the search for inhibitors for the formation of bacterial biofilms, which play an important role in the course of chronic infections. In addition, our scientists are looking for new gene therapy approaches for the treatment of infectious diseases and they are examining whether immune modulators of the pathogens can be possible target structures for new therapeutic approaches. Research fields Analysis of the pathogen-host interactions New pathogen inhibition mechanisms New vaccination strategies New preclinical models Main topics Infection epidemiology Publications Good scientific practice TWINCORE is a joint facility of: © 2015 TWINCORE