Home About Us Research Services Financials / Press Releases Contact Us BIOQUAL STOCK TICKER Influenza Animal Models BALB/c mice Ferrets Various NHPs Study Types Vaccine testing Therapeutics testing PK/safety testing Dose-ranging studies Transfusions ABSL-3 (including Select Agent) and enhanced BSL-2 requiring studies In vitro Services Virus stock generation in embryonated chicken eggs Various H1N1, H2N2, H3N2, H5N1, H7N3, H7N7, H7N9, H9N2 and B virus strains available Sample processing ELISA, HAI and MN assays Infectious and QT-PCR viral load testing Ferret cytokine/chemokine mRNA levels ELISPOT assay Representative Publications Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses. Mytle N, Leyrer S, Inglefield JR, Harris AM, Hickey TE, Minang J, Lu H, Ma Z, Andersen H, Grubaugh ND, Guina T, Skiadopoulos MH, Lacy MJ. Viruses. 2021 Aug 27;13(9):1708. doi: 10.3390/v13091708. PMID: 34578289 Zachary R. Sia, Xuedan He, Ali Zhang, Jann C. Ang, Shuai Shao, Amal Seffouh, Wei-Chiao Huang, Michael R. D’Agostino, Amir Teimouri Dereshgi, Sambhara Suryaprakash, Joaquin Ortega, Hanne Andersen, Matthew S. Miller, Bruce A. Davidson, Jonathan F. Lovell. A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge. Proceedings of the National Academy of Sciences Jun 2021, 118 (22) e2025759118; DOI: 10.1073/pnas.2025759118. Masaru Kanekiyo, M. Gordon Joyce, Rebecca A. Gillespie, John R. Gallagher, Sarah F. Andrews, Hadi M. Yassine, Adam K. Wheatley, Brian E. Fisher, David R. Ambrozak, Adrian Creanga, Kwanyee Leung, Eun Sung Yang, Seyhan Boyoglu-Barnum, Ivelin S. Georgiev, Yaroslav Tsybovsky, Madhu S. Prabhakaran, Hanne Andersen, Wing-Pui Kong, Ulrich Baxa, Kathryn L. Zephir, Julie E. Ledgerwood, Richard A. Koup, Peter D. Kwong, Audray K. Harris, Adrian B. McDermott, John R. Mascola & Barney S. Graham. Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nature Immunology, volume 20, pages 362–372 (2019). DiNapoli, J. M., Nayak, B., Yang L., Finneyfrock B.W., Cook A., Andersen H., Torres-Velez F., Murphy B., Samal S. K., Collins P. L., and Bukreyev A. Newcastle disease virus-vectored Vaccines expressing the hemagglutinin or neuraminidase protein of H5N1 highly pathogenic avian influenza virus protect against virus challenge in monkeys. J. Virol. 2009 Nov. 18 Wei CJ, Boyington JC, McTamney PM, Kong WP, Pearce MB, Xu L, Andersen H, Rao S, Tumpey TM, Yang ZY, Nabel GJ. Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination. Science. 2010 Jul 15. PMID: 20647428. Yassine HM, Boyington JC, McTamney PM, Wei C-J, Kanekiyo M, Kong W-P, Gallagher JR, Wang L, Zhang Y, Joyce MG, Lingwood D, Moin SM, Andersen H, Okuno Y, Rao SS, Harris AK, Kwong PD, Mascola JR, Nabel GJ, and BS Graham. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nature Medicine (2015). 24 August. doi:10.1038/nm.3927. BIOQUAL, Inc. Partnering with government, academic, and commercial organizations to provide innovative research support for improved global health Your Full Name Phone Number Email Address Message 240-404-7654 800-208-3149 info@bioqual.com BIOQUAL, Inc. 9600 Medical Center Drive Suite 101 Rockville, MD 20850-3336 Copyright © 2021, BIOQUAL, Inc. All Rights Reserved. Website Design by Studio98