0 items Products FabALACTICA FabRICATOR FabRICATOR Enzyme FragIT & FragIT Kit FabRICATOR LE FabRICATOR Validation Kit Anti-FabRICATOR FabRICATOR Z FabRICATOR Z Enzyme FragIT Z & FragIT Z Kit FabULOUS FabULOUS Enzyme FabULOUS Fab kit GingisKHAN GingisKHAN Enzyme GingisKHAN Fab kit GingisREX IgGZERO IgGZERO Enzyme IgGZERO LE deGlycIT GlycINATOR GlycINATOR Enzyme GlycINATOR LE Immobilized GlycINATOR GlyCLICK Enzymes for O-glycans OglyZOR OpeRATOR SialEXO Services Applications Antibody Characterization Antibody Drug Conjugate Characterization Antibody Oxidation Antibody Subunit Fragmentation FabRICATOR in QC Applications mAb Quality in Cell Culture Mass Spectrometric Analysis of Antibodies Deglycosylated IgG Level of Afucosylation Enhancing mAb Efficacy Mass Spectrometric Analysis of Antibodies Preparative Applications Production of Fab Fragments Generation of F(ab’)2 Fragments GlyCLICK Conjugation SmartEnzyme Reference Tool Contact How to Order Support FAQ Store Antibody Fragmentation Enzymes for O-glycan Analysis GlyCLICK Glycosidases Proteases About Careers Investor Blog From the Blog | Genovis provides unique enzymes for rapid characterization of antibody based biotherapeutics; monoclonal antibodies (mAbs), antibody drug conjugates (ADCs), Fc-fusion proteins, biosimilars etc. The SmartEnzymes™ portfolio consists of FabRICATOR® (IdeS), FabRICATOR®Z (IdeZ), FabULOUS® (SpeB), GingisKHAN® (KGP), GingisREX™ (Rgp), IgGZERO® (EndoS) and GlycINATOR® (EndoS2). GlyCLICK™ – New Antibody Labeling Technology Quantitative and site specific labeling of IgG Precise and complete conjugation Modular technology Reliable performance IgG Proteases IgG Glycosidases Proteases Conjugation O-glycans Sign Up for Genovis' Newsletter: Subscribe Upcoming Events VIB - Antibody Technology Conference, 2017 Oct 16-17, 2017 Ghent European Antibody Congress, 2017 Oct 31-Nov 2, 2017 Basel PEGS Europe, 2017 Nov 13-17, 2017 Lisbon Antibody Engineering San Diego 2017 Dec 11-15, 2017 San Diego Latest References GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies 2017-08-14 Moelleken J, Endesfelder M, Gassner C, Lingke S, Tomaschek S, Tyshchuk O, Lorenz S, Reiff U, Mølhøj M. Preclinical Characterization of CTL-1, A Biosimilar Anti-EGFR Monoclonal Antibody for Cetuximab 2017-08-10 Peisheng Hu, Ryan Gra, Long Zheng, Leslie A Khawli and Alan L Epstein Enzyme Reference Tool Find the right reference for the antibody attribute you are studying using the Enzyme Reference Tool that organizes all papers published using Genovis enzymes. Download our Brochures & Posters Next Day Delivery! For orders placed before 2 pm we ship same day for next day delivery within Europe and North America. Within these regions we add no shipping charge. For instructions on how to place orders from US and Canada - Click here. Follow the following link to receive W9 form and contact information for Genovis Inc - US Vendor Setup For Europe and Rest of World click here FabRICATOR (IdeS) a cysteine protease for digestion of IgG at one single site below the hinge Site specific and quantitative conjugation of functional groups to antibody Fc-glycans GingisKHAN (KGP) a unique cysteine protease that cleaves HUMAN IgG1 at one single site just above the hinge GlycINATOR (EndoS2) is an endoglycosidase with a unique specificity for native IgG FabULOUS (SpeB) is a cysteine protease that digests IgG above the hinge GingisREX (Rgp) specifically digests peptides and proteins C-terminally of arginine residues FabRICATOR Z (IdeZ) a cysteine protease for digestion of mouse IgG2a at one single site below the hinge. IgGZERO (EndoS) is an endoglycosidase with a unique specificity for native IgG IgG Proteases IgG Glycosidases Proteases Conjugation O-glycans EMEA & Asia Genovis AB Box 790 SE-220 07 Lund Sweden 0046 (0)46 101230 USA & Canada Genovis Inc 245 First Street, suite 1800 Cambridge, MA 02142 USA (617) 444-8421 Customer Support How to order FAQ Contact support Terms & Conditions References Products Online store Corporate About us Investor relations Contact IR Facebook LinkedIn We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok