HOME BOOKSTORE USEFUL LINKS CONTACT US Hyaluronic Acid (Sodium Hyaluronate) An innovative way to thermally sterilize Hyaluronic Acid Pre-filled Syringes Several reports on degradation of HA involving microwaves, UV or γ-rays have been published. Rheological studies also show that HA solutions degrade at high temperature: viscosity of the solutions decreases in time as a function of temperature. Therefore, the thermal sterilization treatment of HA solutions represents a great challenge. An optimized moist-heat sterilization cycle can minimize product degradation (and change of molecular weight) maintaining the required viscosity for the specific application. Author: Bernuzzi, Maria Luisa. Gori, Andrea. Process Aseptic processing Chemical bio-decontamination Cleaning Moist-heat sterilization Sterilization Application General(23) Environmental Monitoring(1) Hyaluronic Acid (Sodium Hyaluronate)(1) Package Integrity(1) Blood bags(2) Food(4) Pharma - Liquids(10) Pharmaceutical compounding(2) Pre-filled syringes (PFSs)(4) Robotics(2) Sealed containers(4) Validation(8) Other applications(8) Search Enter your keyword Process Select a process Aseptic processing Chemical bio-decontamination Cleaning Dry-heat sterilization Moist-heat sterilization Standards & regulations Sterilization Application Select an application Blood bags Environmental Monitoring Food General Hyaluronic Acid (Sodium Hyaluronate) Other applications Package Integrity Pharma - Liquids Pharmaceutical compounding Pre-filled syringes (PFSs) Robotics Sealed containers Validation Author: Select an author Mascherpa Vittorio Agalloco James Korczynski Michael S. Moldenhauer Jeanne Akers James Ferretti Sara Bernuzzi Maria Luisa Pistolesi Dario Mauri Sergio Sandle Tim Thorogood Doug Gori Andrea Member area If you are a registered user enter your e-mail address and password to log in. E-mail Password register! forgot your password ? About us What do you find here? Useful and detailed technical information regarding sterilization, bio-decontamination and cleaning processes. We aim to share our passion and knowledge providing valuable information for a better understanding of technologies, processes and equipment currently available in the market. This way, we hope to enhance good manufacturing practices and shape innovation. Who can benefit from our content? We offer a rich source to support students, researchers and professionals with high-quality papers and presentations. Who are we? Our collaborators are recognized and passionate professionals bringing together many years of experience on the above mentioned fields. How does it work? You can browse the articles by searching a term, category, subject or author. All the blog content is available for free, you just need to register to have full access to it. Contact us info@sterilize.it If you have any suggestion, comment or question, please contact us. If you would like to collaborate with technical documents, please contact us. Any material is subject to approval by our Scientific Committee. Follow us Newsletter Name Surname E-mail I accept the processing of my personal data in accordance with article 13 Legislative Decree 196/2003. © Copyright 2015 Sterilize.it. All rights reserved.