Germline The BRCA Germline test is designed to detect Hereditary Breast and Ovarian Cancer Syndrome on a simple blood sample. ORDER NOW LEARN MORE Who Should Be Tested BRCA1/2 testing is only recommended for certain population or individuals with a high risk of having a BRCA1/2 gene mutation, including those with: if the mutation in the family is known you are not going to do this test A personal history of breast cancer at age 45 or younger A personal history of breast cancer at any age AND a family member (parent, sibling, child, grandparent, uncle, aunt, nephew, niece or first cousin) diagnosed with breast cancer at age 50 or younger A personal history of breast cancer at any age AND two or more family members diagnosed with breast, pancreatic and/or prostate cancer at any age Ashkenazi Jewish heritage and a personal history of breast or pancreatic cancer A personal history of triple negative breast cancer (breast cancer that is estrogen receptor-negative, progesterone. receptor-negative and HER2-negative) diagnosed at age 60 or younger A personal or family history of ovarian cancer A personal or family history of male breast cancer A family member (parent, sibling, child, grandparent, uncle, aunt, nephew or niece) diagnosed with breast cancer at age 45 or younger Clinical Utility The BRCAtest provides valuable information that can be utilized for reducing the risk of cancer development or recurrence by assisting the treating physicians to individualize surgical and pharmaceutical management. In addition, it can be used to identify those family members at risk of developing cancer who can benefit from risk reduction management. Furthermore, those family members that do not carry the pathogenic mutation identified in the family can be relieved of the stress of developing hereditary cancer and forego unnecessary interventions. FAQS What types of cancer does it cover? If a pathogenic mutation is found, should my family members be tested? In how many days will my results be available? What specimen type is required for the BRCAtest Germline? Is the test covered by any public/private insurance? How do I make the payment for the test? How can I send my sample and receive my results? Can I have my blood drawn at Genekor? Why should I sign the consent form? Possible Outcomes A negative report indicates that no clinically significant mutation has been identified. In this report you will find an interpretation of the findings along with details about non-clinically significant variants. A positive report indicates that a pathogenic mutation was identified. In this report you will find details about the variant detected and extensive interpretation of the risk of the individual, along with analysis of the findings. A VUS (Variant of Uncertain Clinical Significance) report indicates that the available data (published and in silico analyses) are not enough to characterize the variants identified in this individual, as pathogenic or benign. In these cases, clinical management should be based on personal and family history. VUS results should not be used in predictive testing of at risk relatives. How to get Started 1 Order the test Ask your physician if you are eligible for the BRCA Germline test. 2 Sample requirement A blood sample is required for this test (2 EDTA vials). Your sample will be collected per your physican's instructions. 3 Analysis Process Your sample will arrive to to our accredited laboratory and your report will be generated and released to you and your physician in 15 days 4 Reporting Your report will be electronically released to your physician via email and/or uploaded to our secure portal, and to you via mail. Technical Info BRCA Germline test is designed in order to achieve maximum sensitivity and specificity. All findings are classified using the most reliable, updated databases and in silico analysis algorithms. Advanced Next Generation Sequencing Technology, also known as NGS, is used to fully analyze the BRCA1 and BRCA2 genes that are related to Hereditary Breast and Ovarian Cancer Syndromes (HBOCS). How to order Our dedicated Client Service Team is committed to answer your questions with regards to the services offered by Genekor. If you would like to order any of the tests that Genekor performs please contact us directly. Please click here to see the specimen preparation and shipping instructions If you would like to send us your sample, contact us in order to arrange for all the logistics. Please click here Download Forms you are already aware of the process of sending a sample, in order to download all the related forms. Please click here About Contact us © 2017 GENEKOR MEDICAL S.A. All rights reserved | Terms of Use | Secure Transactions | Sitemap Committed to biotechnological innovation Change cookies consent Revoke cookies consent