PLATFORM Publications Technology Platform Stimulatory Products Tolerogenic Products Product Advantages Intellectual Property Publications Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Johnston LP, Kishimoto TK. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine. 2014 Mar 1. [Epub ahead of print] Fraser CC, H Altreuter D, Ilyinskii P, Pittet L, Lamothe RA, Keegan M, Johnston L, Kishimoto TK. Generation of a universal CD4 memory T cell recall peptide effective in humans, mice and non-human primates. Vaccine. 2014 Feb 26. [Epub ahead of print] Mamo T, Moseman EA, Kolishetti N, Salvador-Morales C, Shi J, Kuritzkes DR, Langer R, von Andrian U, Farokhzad OC. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (Lond). 2010 Feb;5(2):269-85. Fraser, C. Nanoparticle Therapy for Allergic and Inflammatory Disease. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 2010;9:54-70 Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn MP, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat Immunol. 2008 Mar;9(3):282-91. Epub 2008 Jan 20. Mempel TR, Pittet MJ, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Andrian UH. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity. 2006 Jul;25(1):129-41. Junt T, Moseman EA, Iannacone M, Massberg S, Lang PA, Boes M, Fink K, Henrickson SE, Shayakhmetov DM, Di Paolo NC, van Rooijen N, Mempel TR, Whelan SP, von Andrian UH. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. 2007 Nov 1;450(7166):110-4. Henrickson SE, von Andrian UH. Single-cell dynamics of T-cell priming. Curr Opin Immunol. 2007 Jun;19(3):249-58. Mempel TR, Henrickson SE, Von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature. 2004 Jan 8;427(6970):154-9. von Andrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol. 2003 Nov;3(11):867-78. von Andrian UH, Mackay CR. T-cell function and migration. Two sides of the same coin. N Engl J Med. 2000 Oct 5;343(14):1020-34. Gu F, Zhang L, Teply BA, Mann N, Wang A, Radovic-Moreno AF, Langer R, Farokhzad OC. Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2586-91. Epub 2008 Feb 13. Farokhzad OC. Nanotechnology for drug delivery: the perfect partnership. Expert Opin Drug Deliv. 2008 Sep;5(9):927-9. Langer R. Drug delivery and targeting. Nature. 1998 Apr 30;392(6679 Suppl):5-10. Review Zhang L, Chan JC, Gu F, Rhee JW, Wang AZ, Radovic-Moreno AF, Alexis F, Langer R and Farokhzad OC. Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform. ACSNano 2008 2(8):1696-1702 © 2014 Selecta Biosciences, Inc. | 480 Arsenal St., Building One, Watertown, MA 02472 | Phone: 617-923-1400 | Fax: 617-924-3454 | Email: info@selectabio.com Privacy Policy | Web site designed and developed by RainCastle Communications, Inc.