Share page on Facebook Share page on Twitter Share page on LinkedIn Home Therapeutics Cardiovascular ICON has extensive experience in cardiovascular clinical research trials across the entire drug development spectrum. Despite the advances in the cardio-metabolic field over the past 20 years, cardiovascular and metabolic diseases remain the leading causes of morbidity and mortality worldwide. The need to discover and develop better, safer and more cost-effective drugs and devices remains. ICON, a full-service provider, takes a data-driven approach to develop strategies that will cut timelines and costs from First-in-Human (FIH) studies through post-approval. We have over 25 years of experience conducting cardiovascular trials with particular emphasis on key cardiovascular/metabolic indications: heart failure, lipid disorders, diabetes, renal insufficiency and renal transplant, arrhythmia, and rare diseases. ICON Cardiovascular experience in the last five years 710,000+ Patients 660+ Studies 28,700+ Sites ICON's experienced cardio-metabolic drug and medical device development teams support clinical trials across multiple indications, including: Cardiovascular Atrial and Ventricular Arrhythmia Cardiomyopathy (e.g., ATTR, hypertrophic, etc. with rare disease team) Heart failure Hypertension Pulmonary Hypertension (with the respiratory team) Coronary Artery Disease and Stable Angina Acute Coronary syndromes, including myocardial infarction Venous Thromboembolism Peripheral Arterial Disease Atherosclerotic & embolic cerebrovascular disease Stroke, TIA (with neurosciences team) Metabolic Diabetes Dyslipidemia Hyperuricemia ICON services across all phases of drug and device development for your cardio-metabolic trials: Drug & Device Development Medical Device & Diagnostics Research Adaptive Study Design Phase I Research Feasibility Assessment Site & Patient Solutions Medical Imaging Endpoint Adjudication Services Central Laboratories Drug & Device Development Therapeutic advisors in cardiovascular disease available to consult with sponsors, as well as to provide leadership to study teams. Explore Medical Device & Diagnostics Research ICON has deep experience with the development and commercialisation of medical devices, medical device software, in vitro diagnostics, drug delivery systems/devices and combination products across all key cardiovascular indications. Explore Adaptive Study Design Market-leading simulation software and methods to perfect trial design Explore Phase I Research A 120-bed unit with pharmacy, labs, and ECG system. Explore Feasibility Assessment Access to a global team of experts and data scientists using an evidence-based approach to accurately estimate enrolment and study timelines. Explore Site & Patient Solutions Transforming recruitment through patient-centric trials and real-world, real-time data Explore Medical Imaging Integrated solutions based on the science of imaging biomarkers and experience in all cardiovascular imaging modalities. Explore Endpoint Adjudication Services Endpoint Adjudication can help lower the risk of variation in important clinical trial outcome events for submission to regulatory agencies. Explore Central Laboratories Global central laboratories with industry-leading accuracy for CVM study endpoints. Explore Dedicated specialist teams ICON has a global team of in-house cardio-metabolic experts who are highly-experienced in clinical research and drug and device development. The group includes representatives from all critical functional areas and oversees trial operations in order to anticipate and proactively address potential roadblocks. We also leverage established and new relationships with renowned cardio-metabolic experts and investigators worldwide to benefit our clients. In addition to providing support and guidance to the study team, our cardio-metabolic experts provide insight on: Global project feasibility Protocol development, review and evaluation Clinical trial planning Therapeutic training and advice Project oversight Consulting, medical monitoring and advisory board representation Interpretation of the clinical data Completion of the clinical study report Accellacare Our global investigator database includes over 5,800 cardiovascular investigative sites across more than 55 countries. As such, we have established solid working relationships with leading cardiovascular sites in all regions of the world, enabling us to provide our sponsors with efficient recruitment strategies tailored to each study. Learn more Cardiovascular, Metabolic and Circulation insights ICON's Cardiovascular team contributes regularly to industry publications and media coverage of cardiovascular clinical trials. Stay up to date with ICON's latest thought leadership on cardiovascular clinical trials. Read more IN THIS SECTION Cardiovascular Cell and Gene Therapies Central Nervous System Endocrine & Metabolic Disorders Infectious Diseases Internal Medicine & Immunology Medical Device Oncology Paediatrics Rare & Orphan Diseases Transplant Immunology Women's Health Vaccines Therapeutics insights Connect with us Contact us Submit proposal request Update Email Preferences Global office locator ICON on social media Related information WEBPAGE Cardiovascular, metabolic and circulation insights BROCHURE Medical Imaging - Cardiovascular FACTSHEET Cardiovascular / Metabolic Clinical Trials: Capabilities Overview Next 1 2 Cardiovascular Social Media Posts Contact About ICON Results & Reports For Clients Therapeutics Services Insights Innovation Content Preferences Office locations ICON For Patients Volunteers Investigators Jobs & Careers Investors Suppliers News & Events Press Releases Mediakit Events Social Media Dashboard LinkedIn Twitter Facebook Youtube © 2021 ICON plc Disclaimer Privacy Site Cookies We use cookies on this website We use cookies to enhance your website experience. We use necessary cookies to ensure our website functions properly and to keep it secure. These always need to be on. By clicking “Accept all”, you agree to the storing of cookies on your device to enhance site navigation, analyse site usage, and assist in our marketing efforts. Please view our cookie policy for further details.. Accept all Manage cookies