Home Vision Mission & Strategy Optimise and Innovate compounding Fagron Values Our values define what we are and what we aim to be Benefits of Compounding Pharmaceutical compounding creates added value in patient care Cases Bringing innovative solutions Fagron Advanced Derma Leading advanced dermatological care Code of Conduct & Ethics Doing business as a global market leader Knowledge Knowledge Search Search form Compounding MSDS CoA Search Our Innovative Products Innovative concepts and solutions for all challenges in compounding pharmacies View our innovative products Compounding Matters Fagron's database of compounding formulations Documents (MSDS & CoA) Documents (MSDS & CoA) Terminology List Terminology list R&D Research & Development Matching the most optimal tailor-made medication with the patient’s needs is the essence of compounding. Pipeline Tailor-made pharmaceutical solutions and concepts that significantly improve patients' lives. Dermatology Fagron Advanced Derma is the global standard for advanced individual dermatological care. Pain Our R&D department focuses on a concept aimed at pain management which will be introduced in 2015. Oral Suspending Vehicles With SyrSpend® SF, Fagron enables pharmacists to efficiently prepare stable oral liquid dosage forms. Quality Quality Management More than 200,000 customers have access to over 5,000 high-quality pharmaceutical raw materials Quality Activities Quality tasks in coordination with procurement, sales, production and in general Supplier qualifications and audits Qualification of a product is a cooperation between Fagron Procurement and Fagron Quality Falsified Medicines Directive The Falsified Medicines EU Directive 2011/62/EU is in force from 2 July 2013 Documentation and Records To go further in meeting our customers’ needs Company Fagron Foundation Fagron contributes to improve the welfare of children Fagron Academy Training courses and lectures to enhance compounding skills and knowledge Careers Explore Fagron's career opportunities Fagron Executive Committee Introduction members of Fagron Executive Committee News Latest news items and news archive Fagron History From local player to global market leader in pharmaceutical compounding World Press Investors Enter your keywords Search in Website Search in MSDS Search in CoA Case study: Koji has a large wound on his shoulder Koji's case The challenge The Case During a mountain bike trip with his friends, Koji loses control of his bicycle and falls. He calls in at the local hospital’s first aid with a large cut on his shoulder. After the wound has been cleaned, Koji receives multiple stitches. The challenge The solution The Challenge Koji has a family history of being more prone to hypertrophic scarring. His physician therefore considers prescribing him silicones, the gold-standard prophylactic for hypertrophic scars. The solution The Cure The Solution Nourisil™ is an ultra-light, ready-to-use, silicone base that allows for compounding with a wide range of APIs. Its formula contains a unique blend of silicones and vitamin E, which enhances the wound healing process and helps to prevent scars. The cure Cases overview The Cure Koji is prescribed Nourisil™ twice a day to achieve maximum results. After three months, Koji’s scar is minimally visible and his next mountain bike trip has already been planned. Case study: Miquel has high blood pressure Miquel's case The challenge The Case Miguel (age three) has a genuine sweet tooth and healthy appetite. He happily eats any treat his mother gives him, but she is a little concerned. Last time they visited their family doctor, Miguel’s blood pressure was up in the 95th percentile for boys of his age. Today, the doctor checks his blood pressure again and diagnoses hypertension. He also tests for diabetes and wants to start Miguel on a dose of atenolol at 0.5 mg/kg/day, once-daily, to treat his hypertension [1]. [1] The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Bethesda, MD: U.S. Department of Health and Human Services, National Institutes of Health and National Heart, Lung, and Blood Institute; 2005. NIH Publication No. 05-5267. The challenge The solution The Challenge Miguel weighs 17 kg, so his doctor wants to prescribe him 8.5 mg atenolol per day. As this dosage is commercially unavailable, he calls the pharmacist to discuss compounding an oral suspension. Although he is concerned about giving young Miguel a suspension with preservatives and a high sugar content, he is not sure whether Miguel will accept his medication without taste masking. The solution The Cure The Solution The pharmacist has the perfect solution for Miguel’s situation. He suggests compounding a 1 mg/ml atenolol suspension with the Atenolol & SyrSpend® SF PH4 kit. SyrSpend® SF PH4 is sugar and preservative-free and has excellent taste-masking properties as well as a sweet, neutral taste. Beginning with a 1 mg/ml suspension, the dose can be adjusted over time as Miguel develops. The cure Cases overview The Cure Six months later, Miguel’s blood pressure has improved and his doctor wants to try to start lowering the dose of atenolol. The pre-diabetes signs that were initially present have diminished and almost gone. His mother has also cut back on the treats, and Miguel has become a lively young fellow. The doctor hopes to eventually have Miguel come off the medication completely. Case study: Josh has problems swallowing Josh's case The challenge The Case Josh (51 years old) is recovering from a Laryngeal cancer treatment. He’s doing well but he’s having problems swallowing solid food and medication. His wife is currently suffering a bad flue. Since Josh’s immune system is considered to be acquired after his cancer treatment his oncologist wants to prescribe Josh an oseltamivir treatment to prevent him from developing influenza as well. The challenge 1 2 3 4 next The Challenge Patient accessibility: Because Josh is having problems swallowing he needs a liquid dosage form, which is not available as a licensed product in the right dosage strength for Josh. 1 2 3 4 next The Challenge Patient acceptance: Josh is experiencing retching when feeling an unpleasant bitter taste in his mouth. Oseltamivir has a bitter taste. 1 2 3 4 next The Challenge Unpleasant side effects: Josh is suffering diarrhea and other gastrointestinal discomfort due to his cancer medication. Stomach distress and diarrhoea are seen with sorbitol containing suspending vehicles. 1 2 3 4 The Challenge Proven stability: The stability of oseltamivir in a fluid form needs special attention. The solution 1 2 3 4 5 next The Solution With the focus on patient, prescriber and pharmacist, Fagron offers unique solutions that add significant value in the individualized treatment of patients with specific needs. Also for Josh. 1 2 3 4 5 next The Solution Patient accessibility: With SyrSpend® SF PH4 it is possible for a pharmacist to easily compound a 15 mg/ml oseltamivir suspension for Josh, based on oseltamivir capsules. SyrSpend® SF PH4 can be used with a broad variety of active pharmaceutical ingredients (APIs) so the pharmacist can keep SyrSpend® SF PH4 on stock for similar cases similar cases. 1 2 3 4 5 next The Solution Patient acceptance: SyrSpend® SF PH4 is available in cherry flavour and unflavoured, both with taste-masking capacities to cover the bitter taste of oseltamivir. Flavouring concentrates from the SyrSpend® SF Flavouring Kit may be added to the neutral versions to customise to Josh’s individual preference. 1 2 3 4 5 next The Solution Unpleasant side effects: Low osmolality of SyrSpend® SF PH4 minimizes the risk of stomach distress and diarrhoea seen with traditional sorbitol containing suspending vehicles. The suspension prepared with SyrSpend® SF PH4 is free from alcohol, parabens, sorbitol, sugars, gluten and colourants. SyrSpend® SF PH4 is also available as a preservative-free powder for reconstitution. 1 2 3 4 5 The Solution Proven stability: Stability tests have proven a 30 days stability of a suspension of SyrSpend® SF PH4 with oseltamivir*. The cure 1 2 next The Cure A simple process of mixing the oseltamivir capsule contents with SyrSpend® SF PH4 enables the pharmacist to prepare a stable suspension in just minutes for Josh. 1 2 The Cure Josh is doing really well. He did not get caught by the influenza virus, his energy level is improving and he’s eating more and more solid food again. Last week he and his wife booked a holiday out of their dreams to Hawaii and he’s looking forward to it. Josh is enjoying life. * Voudrie MA, Allen DB. Stability of oseltamivir phosphate in SyrSpend® SF, cherry syrup, and SyrSpend® SF (for reconstitution). Int J Pharm Compd. 2010;14(1):82-85. Case study: Steve has an unpleasant dry skin feeling Steve's case The challenge The Case Steve required a repeat prescription of benzoyl peroxide 5% and clindamycin HCl 1% in a gel for his acne. He complained to his pharmacist, Mr Nguyen, about the amount of time needed to apply the two products and an unpleasant dry skin feeling after frequent use. The challenge The solution The Challenge Due to Steve’s dehydrated skin condition, a cream would be better for his skin type than a gel, and combining both APIs in a single formulation would be preferable. The solution The Cure The Solution By compounding with the unique Fagron trademark vehicles from Fagron Advanced Derma, pharmacists are able to deliver exclusive solutions that add significant value and offer tailor-made treatment to patients. Patient satisfaction, therapy compliance and patients’ quality of life are thus improved. The cure Cases overview The Cure Mr Nguyen compounded benzoyl peroxide 5% and clindamycin HCl 1% in Versatile™ and was able to deliver an elegant single cream solution to Steve. Case study: Laura has been struggling with the symptoms of mild psoriasis Laura's case The challenge The case Laura has been struggling with the symptoms of mild psoriasis for the past few years. She recently had an interview for a position as a flight attendant - her dream job. She visits her dermatologist to inquire about treating her symptoms with a more comfortable preparation than the one she already uses. The challenge The solution The challenge Psoriasis is often treated with traditional ointments, which can be very greasy and highly uncomfortable. Especially considering the fact that Laura will have to wear a uniform for stretches of time. The solution The Cure The solution Laura’s dermatologist has positive experiences with combinations of topical corticosteroids and emollients. Considering the dryness of the affected skin, he suggests an innovative ointment-based preparation. To guarantee Laura maximum comfort and results during therapy, he proposes Occluvan™, a Fagron Advanced Derma vehicle. The cure Cases overview The cure The dermatologist asks Laura’s pharmacist to compound clobetasol proprionate 0.05% and dexpanthenol 3% in Occluvan™, an innovative ointment base with minimal tackiness. Laura is very satisfied with the preparation’s elegance and comfortable skin feel. She now has her symptoms under control and recently received the news that she has been hired as a flight attendant. Steve has an unpleasant dry skin feeling Pages 1 2 3 4 5 Register | Login Global market leader in pharmaceutical compounding Our ability to listen to our customers and to work closely together with pharmacists, prescribers and universities worldwide is the foundation of our successful strategy of optimising and innovating pharmaceutical compounding Learn more about compounding News: Fagron reshapes the U.S. Sterile Compounding Industry Fagron North America will open one of the largest 503B human drug outsourcing facilities in the U.S. in November... Read this article Latest Fagron product innovations Ultra-light serum SERAQUA™ Silicone base NOURISIL™ Oil base SOLYDRA™ Ointment base OCCLUVAN™ Cold cream EMOLIVAN™ Vanishing emulsion NOURILITE™ Antioxidant cream NOURIVAN™ ANTIOX View innovations Welcome to Fagron No front page content has been created yet. Videos Accu-Tenth Pentravan Lollibase Espumil Versatile Capsicards® System "Fagron Foundation" The goal is to leverage human and financial resources to drive social change and healthcare and community improvements. The main focus is on improving the welfare of children. Visit Fagron Foundation Read more Fagron Channels Patient care started with compounding. Compounding still matters. Read more Fagron offers young pharmacists a comprehensive one year tailor-made training program. Read more The local partner programs shows our appreciation to our loyal customers. Read more Fagron provides training courses to pharmacists to further enhance their skills in the pharmaceutical compounding of tailor-made medication. Read more The goal is to leverage human and financial resources to drive social change and healthcare and community improvements. Read more Fagron TV is a new channel developed by Fagron to provide more knowledge about compounding. 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