HOME ABOUT US SERVICES PRODUCTS TECHNOLOGIES INFO CENTER CONTACT US Overview & Capacities Overview Phosgenation Hydrogenation Halogenation Cryogenic chemistry Distillation PMC Isochem has developed over 40 years a first class technology platform offering to our customers a competitive development and manufacturing cGMP service with a strong position in hazardous chemistry. Your benefits from PMC Isochem’s offer Chemistry and process expertise Large scale multi-step synthesis Handling large volumes of hazardous materials Large scale HSE risk management track-records Reliable and competitive solution PMC Isochem operates 3 cGMP production sites with a total reaction capacity of 240 m3. PMC Isochem runs a large range of glass-lined and stainless steel vessels, from 100 L to 10.000 L, coupled with equipment for liquid and solid purification and separation. API, regatory registered intermediates, starting materials and other chemicals are produced in the three sites. Manufacturing facilities (cGMP sites) Reaction-Process (59 equipments) 240 m3 - 0.1 to 10 m3 Glass-lined 190 m3 (33 eq.) Stainless steel 65 m3 (25 eq.) Halar coated 1 m3 (1 eq.) 40 bar Biazzi hydrogenator Filtration (33 equipments) Stirred filter (18 eq.) up to 5 m2 Including filter dryer : 6 Including anti-corrosion (Hastelloy C) : 5 Centrifuge (9 eq.) Press Filter (6 eq.) Including 1 automatic (LAROX) Finishing (21 equipments) Stirred dryer (6 eq.) up to 2500 L Tray oven (15 eq.) Sieving and Milling Clean rooms: class 100.000 and class D Distillation (8 equipments) Batch Glass-lined (5 eq.) & Stainless Steel (2 eq.) 100 to 1800 L – up to 15 plates Wiped Film (Hastelloy C) 0.3 m2 - 600 kg/day Purified water Clean room: class 100.000 and class D Copyright © PMC ISOCHEM 2018 Login Sitemap Legal notice

HOME ABOUT US SERVICES PRODUCTS TECHNOLOGIES INFO CENTER CONTACT US Cryogenic chemistry Overview Phosgenation Hydrogenation Halogenation Cryogenic chemistry Distillation PMC Isochem’s offer covers cGMP cryogenic reactions. This industrial capability combined with know-how in organometallic chemistry and asymmetric reactions is a valuable tool into the multistep synthesis industrial platform. Your benefits from PMC Isochem’s offer Technology expertise Organometallic chemistry, deprotonation, halogen exchange, rearrangement Asymmetric reactions Custom manufacturing cGMP custom manufacturing reaction at -70°C at 3000 L scale (two vessels) Chemistry and handling of Lithium organometallic reagents (Alkyl lithium, lithium amides …) Access to boronic acid intermediates and downstream coupling reactions Access chiral intermediates from asymmetric reactions First class R&D Our R&D teams are used to work on advanced cryogenic reactions for both rapid evaluation and process development for scale-up of cryogenic reactions. For more information please contact us Copyright © PMC ISOCHEM 2018 Login Sitemap Legal notice