Skip to main navigation News Careers Contact About Science Pipeline Patients Investors INVESTORS Press Releases Events & Presentations Corporate Governance Financials & Filings Stock Information IR Resources AT A GLANCE We are eFFECTOR Therapeutics, a clinical-stage biopharmaceutical company focused on pioneering the development of a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). We believe that our therapeutic approach can inhibit the production of key disease-driving proteins, which tumors have hijacked for their benefit, all while preserving normal cell function. We are currently evaluating our lead product candidate, tomivosertib, a MNK inhibitor, in a randomized, double-blind placebo controlled Phase 2b trial in combination with pembrolizumab in patients with metastatic NSCLC. Zotatifin, our inhibitor of eIF4A, is currently being evaluated in Phase 2a expansion cohorts in certain biomarker-positive solid tumors, including ER+ breast cancer and KRAS-mutant NSCLC. Additionally, we have a global collaboration with Pfizer to develop inhibitors of a third target, eIF4E. We plan to evaluate zotatifin as a potential host-directed anti-viral therapy in patients with mild to moderate COVID in collaboration with the University of California, San Francisco, under a $5 million grant sponsored by the Defense Advanced Research Projects Agency. We are headquartered in San Diego, California. Data Provided by Refinitiv. Minimum 15 minutes delayed. Change: Volume: 11.27.2021 11:33 AM EST View Detailed Stock Information Data Provided by Refinitiv. Minimum 15 minutes delayed. PRESS RELEASES eFFECTOR Therapeutics Announces Publication of Zotatifin Preclinical Data in Frontiers in Oncology 11.24.2021 eFFECTOR Therapeutics to Participate in The JMP Securities Hematology and Oncology Summit 11.22.2021 eFFECTOR Therapeutics Reports Third Quarter 2021 Financial Results and Provides Corporate Update 11.08.2021 View All Press Releases EVENTS JMP Securities Hematology and Oncology Summit 12.06.2021 | 3:20 PM EST Stifel 2021 Virtual Healthcare Conference 11.17.2021 | 3:20 PM EST Credit Suisse 30th Annual Virtual Healthcare Conference 11.08.2021 | 12:10 PM EST View All Events & Presentations Print Page Email Alerts RSS Feeds Search About Science Pipeline Patients Investors News Careers Contact Copyright © 2021 eFFECTOR Therapeutics, Inc. | Privacy Policy