ABOUT COMPANY PRODUCTS DISTRIBUTORS PRESS CENTER SHAREHOLDERS NEWS CONTACTS ENGLISH QUESTION ANSWER MELDONIUM ORGANIC Active ingredient: meldonium dihydrate (trimethylhydrazinium propionate dihydrate). Pharmacological action: structural analogue of gamma-butyrobetaine - a substance that is found in every cell of the human body. Under conditions of increased load, meldonium restores the balance between the delivery and demand of cells for oxygen, eliminates the accumulation of toxic metabolic products in cells, protecting them from damage; also has a tonic effect. As a result of its use, the body acquires the ability to withstand stress and quickly restore energy reserves. As a result of a decrease in the concentration of carnitine, gamma-butyrobetaine, which has vasodilating properties, is intensively synthesized. Indications:in the complex therapy of ischemic heart disease (angina pectoris, myocardial infarction), chronic heart failure and dyshormonal cardiomyopathy, as well as in the complex therapy of acute and chronic disorders of the blood supply to the brain (strokes and cerebrovascular insufficiency). Hemophthalmos and retinal hemorrhages of various etiologies, thrombosis of the central retinal vein and its branches, retinopathy of various etiologies (diabetic, hypertensive). Withdrawal syndrome in chronic alcoholism (in combination with specific therapy for alcoholism). Method of administration and dosage: intravenously, parabulbar. In view of the possible development of an exciting effect, it is recommended to take it in the morning. Cardiovascular diseases.Unstable angina pectoris and myocardial infarction - intravenous stream, 0.5-1.0 g 1 time per day. As part of complex therapy intravenously (5-10 ml of solution for injection 100 mg / ml), applying the entire dose at once or dividing it by 2 times. The course of treatment is 4-6 weeks. Cardialgia against the background of dyshormonal myocardial dystrophy: intravenous stream 0.5-1.0 g once a day, the course of treatment is 10-14 days. Cerebral circulation disorder. The acute phase of cerebrovascular pathology - 500 mg once a day intravenously for 10 days. If necessary, it is possible to conduct a second course. Ophthalmology (hemophthalmus and retinal hemorrhages of various etiologies, thrombosis of the central retinal vein and its branches, retinopathy of various etiologies (diabetic, hypertensive).Parabulbar 0.5 ml of a solution of 100 mg / ml for 10 days. Chronic alcoholism. Intravenous - 500 mg 2 times a day. The course of treatment is 7-10 days. Contraindications: according to the instructions. Adverse reactions: according to the instructions. Special instructions: patients with chronic liver and kidney diseases should be careful with prolonged use of the drug. There is insufficient data on the use of meldonium in children. Many years of experience in the treatment of acute myocardial infarction and unstable angina pectoris in cardiology departments shows that trimethylhydrazinium propionate dihydrate is not a first-line drug for acute coronary syndrome. The safety of using the drug during pregnancy has not been proven. Release form: solution for injection 100 mg / ml 5ml No. 10. Before use, consult a doctor. For more information, see the instructions for use.