(0) Multiomics has transformed traditional sequencing experiments by providing unparalleled protein and genetic analysis on a single-cell or bulk sequencing basis. We offer comprehensive and unique products, including antibodies, panels, and hashtag reagents to enable protein detection by sequencing. Explore the capabilities of TotalSeq™ reagents and see how they seamlessly integrate into existing workflows to uncover what makes each cell unique. TotalSeq™ format antibodies are patent pending proprietary technologies of BioLegend. Contact us if you are interested in partnering with us around this technology. Access our barcode look-up table to view and export barcode information for your antibodies. Find barcodes Products Resources Comprehensive Solutions for Single-Cell and Bulk Multiomics TotalSeq™ oligo-conjugated reagents enable protein detection by sequencing and integrate seamlessly into existing single-cell transcriptomics, bulk sequencing, or single-cell genomics workflows. Choose your experimental goal below and discover our solutions. If you can’t find the reagents you’re looking for, contact us to discuss your project. We offer custom oligo-conjugated reagents including individual antibodies and cocktails. Let us know how we can support your multiomics work. Single-Cell RNA and Protein Detection Compatible with TotalSeq™-A, B, and C reagents. Technologies like CITE-seq and REAP-seq utilize oligonucleotide-conjugated antibodies to simultaneously detect surface proteins and RNA. For this, we offer multiple formats of our TotalSeq™ antibodies, panels, and hashtags to incorporate into single-cell transcriptomics workflows, including Drop-Seq and those offered by 10x Genomics. Explore Applications Multiomics Analysis Software For single-cell RNA and protein data analysis. Processing and analysis of single-cell data can be complicated and require advanced tools. To simplify the process, BioLegend offers Multiomics Analysis Software (MAS), a free cloud-based program for the analysis of multiomics data. Featuring an intuitive user interface with flow cytometry-like gating, the software is accessible to all users irrespective of their bioinformatics background. Analyze Data Bulk RNA Sequencing Compatible with TotalSeq™-A reagents. Bulk RNA-sequencing is commonly used to analyze RNA expression from a population of cells in suspension. Our BEN-seq workflow, developed in collaboration with Illumina, stains cells in suspension with TotalSeq™ oligo-conjugated antibodies prior to bulk RNA sequencing, enabling the simultaneous profiling of cell surface proteins and RNA expression. Expand Bulk Sequencing Single-Cell DNA and Protein Detection Compatible with TotalSeq™-D reagents. Resolve complex genetic questions from genotype to phenotype by combining single-cell DNA analysis with protein detection using TotalSeq™-D oligo-conjugated reagents. Our TotalSeq™-D antibodies and cocktails are constructed for compatibility with the Mission Bio Tapestri platform to enable the co-detection of SNVs/indels, CNVs, and proteins. Learn More Buyer is solely responsible for determining whether Buyer has all intellectual property rights that are necessary for Buyer's intended uses of the BioLegend TotalSeq™ products. For example, for any technology platform Buyer uses with TotalSeq™, it is Buyer's sole responsibility to determine whether it has all necessary third party intellectual property rights to use that platform and TotalSeq™ with that platform. Related Products TotalSeq™-A Reagents TotalSeq™-B Reagents TotalSeq™-C Reagents TotalSeq™- D Reagents Hashtag Reagents Related Pages Bulk Proteogenomics Single-Cell Protein and DNA Single-Cell Protein and RNA MAS Software Tools World-Class Quality. Superior Customer Support. Outstanding Value. 8999 BioLegend Way San Diego, CA 92121 Tel: 877.246.5343 Copyright © 2021 BioLegend, Inc. All rights reserved. LEARN & SHOP Products Web Tools Explore & Learn Pathways Custom Products / Services Custom Panel Construction Promotions Literature GET HELP Technical Support Support Resources Ordering Questions Find a Distributor Contact Us Feedback ABOUT BIOLEGEND Company Careers Blog Privacy Policy Terms Cookie Preferences Tax Forms