Press Releases Conferences & Meetings Presentations & Publications Interactive Scientific Resources Astex in the News Interactive Scientific Resources Astex scientists have released a range of bespoke tools and software, which are available through the sections below. We hope they will be of benefit to the scientific community. Overlay pages Software The overlay pages provide an interactive way of viewing 3D protein-ligand structures from X-ray or cryoEM. Related structures are organized and superimposed to enable easy comparison. The examples below contain structures from recent Astex publications. Fragments to Lead Examples: 2015-2019 All the structural data from the 2021 meta-analysis of fragment-to-lead campaigns is available to view in 3D, as well as interactive versions of the figures from the publication. https://doi.org/10.1039/D1SC03563K View software Contact For questions related to the overlay pages and other software described here, please contact us using the link below. Contact us © Astex Pharmaceuticals All rights reserved Useful links Home Sitemap Privacy Policy Terms of Use Legal Member of the Otsuka Group

UK – Discovery Research USA – Product Development David Rees PhD, FRSC, FMedSci, Chief Scientific Officer David joined Astex in 2003 to lead the chemistry team and in 2017 became CSO. David is associated with the discovery of three launched drugs, the anti-cancer agents ribociclib (Astex Novartis collaboration) and erdafitinib (Astex Janssen collaboration) and the anaesthetic agent sugammadex (Organon, Merck) which has been used in over 30 million patients in 60 countries. David is one of the few industrial scientists to have served as President of the Organic Division of the Royal Society of Chemistry and in 2015 was elected to be a Trustee of the RSC. He has held visiting professorships at three UK universities and sits on several scientific advisory boards of not-for-profit organisations. In 2020 he was elected to the Fellowship of the Academy of Medical Sciences, and was inducted into the RSC BMCS Hall of Fame. Cambridge, UK Astex Therapeutics Ltd. Jeremy Carmichael Senior Vice President, Corporate Development, Head of Business Development Gianni Chessari Vice President, Chemistry Harren Jhoti President and CEO Michelle Jones Vice President, Strategy & Operations, Head of Intellectual Property Neil Jones Senior Vice President, Finance & Operations John Lyons Senior Vice President, Translational R&D Chris Murray Senior Vice President, Discovery Technology Marc O’Reilly Vice President, Molecular Sciences David Rees Chief Scientific Officer Nicola Wallis Senior Vice President, Biology Nicola Wilsher Vice President, DMPK and Preclinical Development © Astex Pharmaceuticals All rights reserved Useful links Home Sitemap Privacy Policy Terms of Use Legal Member of the Otsuka Group We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok