I agree that this site may use cookies for optimising my usage experience. More Information Skip to breadcrumbs Skip to sub nav Skip to doormat 16 labs, 200 scientists, curiosity-driven research: the Research Institute of Molecular Pathology (IMP) is a leading life science centre in Europe. Learn more RESEARCH GROUPS SEE ALL Clemens Plaschka Group Leader mRNA processing and regulation Moritz Gaidt Group Leader Functional genomics of the innate immune system David Haselbach Group Leader Watching molecular machines in action PrevNext CAREER Develop your research project with a world-leading research group. Summer School Find out about opportunities to join a lab for master's research. Master & Internship Join one of the most prestigious international PhD programmes in molecular biology. PhD Programme Grow in a stimulating research environment with world-class scientists and outstanding facilities. Postdocs PUBLICATIONS HIGHLIGHTS SEE ALL Fujihara, Y., Herberg, S., Blaha, A., Panser, K., Kobayashi, K., Larasati, T., Novatchkova, M., Theussl, HC., Olszanska, O., Ikawa, M., Pauli, A. (2021) The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. Corresponding preprint Proc Natl Acad Sci U S A. 118(39) Calderón, L., Schindler, K., Malin, SG., Schebesta, A., Sun, Q., Schwickert, T., Alberti, C., Fischer, M., Jaritz, M., Tagoh, H., Ebert, A., Minnich, M., Liston, A., Cochella, L., Busslinger, M. (2021) Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation. Sci Immunol. 6(61) LATEST PUBLICATONS Scroll and browse the latest publications from the IMP. The most recent papers and pre-prints with IMP scientists as first- or corresponding authors. See all Pre-print The sperm protein Spaca6 is essential for fertilization in zebrafish bioRxiv . 2021.11.19.469324 Pre-print A molecular network of conserved factors keeps ribosomes dormant in the egg bioRxiv . 2021.11.03.467131 Pre-print Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing bioRxiv . 2021.11.03.467109 The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. Proc Natl Acad Sci U S A. 118(39) McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. Elife. 10 HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nat Chem Biol. The Fertilization Enigma: How Sperm and Egg Fuse. Annu Rev Cell Dev Biol. Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma Nature Cancer . 2:693–708 Genome folding through loop extrusion by SMC complexes. Nat Rev Mol Cell Biol. 22(7):445-464 Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation. Sci Immunol. 6(61) TOP EVENTS SEE ALL 02 Dec 2021 IMP Lecture Hall 14:00 Max Birnstiel Award Symposium SYMPOSIUM 09 Dec 2021 Zoom 11:00 Fluorescent and bioluminescent probes for bioimaging Kai Johnsson MPI for Medical Research VBC REGULAR SEMINAR NEWS SEE ALL 24 Nov 2021 CRY2, a component of the bird internal clock Scientists in the Keays Lab have investigated the expression, localisation, and interaction partners of the cryptochrome CRY2 in the pigeon retina.… 08 Nov 2021 Melanie de Almeida wins the Lauwers Award During their doctoral studies, students in the Vienna BioCenter PhD Program present their research three times in Monday Seminar talks to the Vienna… 04 Nov 2021 Vienna BioCenter PhD Awards for two IMP graduates Lisa Haas and Philipp Dexheimer, IMP alumni of the Vienna BioCenter PhD Program, were recognised for their outstanding doctoral research during this… NEWS SEMINARS JOBS CONTACT WEBMAIL INTRANET © 2021, Research Institute of Molecular Pathology (IMP) Imprint & Privacy