ABOUT US TEAM PLATFORMS PRODUCTS NEWS JOIN OUR TEAM Harnessing the power of CRISPR to bring the next generation of diagnostics to the people who need them most OVERVIEW Powerful platforms for disease detection. SHERLOCK™ utilizes CRISPR as a method for “smart amplicon detection” and can be adapted for use in a single cartridge as part of a simple point-of-care system or deployed to multiplex over 100 targets, allowing laboratory technicians to improve time to result by testing multiple patient samples at once. The adaptability of SHERLOCK, coupled with its ability to precisely identify nucleic acid sequences, makes it a critical addition to the arsenal of diagnostics, enabling physicians to make on-the-spot healthcare decisions for patients in a single visit. Engineering Biology SHERLOCK for SARS-CoV-2 Listen to our CTO William Blake discuss our SHERLOCK platform What is SHERLOCK™? SHERLOCK is an evolution of CRISPR technology, which others use to make precise edits in genetic code. SHERLOCK can detect the unique genetic fingerprints of virtually any DNA or RNA sequence in any organism or pathogen. Developed by our founders and licensed exclusively from the Broad Institute, SHERLOCK is a method for single molecule detection of nucleic acid targets and stands for Specific High Sensitivity Enzymatic Reporter unLOCKing. It works by amplifying genetic sequences and programming a CRISPR molecule to detect the presence of a specific genetic signature in a sample, which can also be quantified. When it finds those signatures, the CRISPR enzyme is activated and releases a robust signal. This signal can be adapted to work on a simple paper strip test, in laboratory equipment, or to provide an electrochemical readout that can be read with a mobile phone. PERFORMANCE AND ATTRIBUTES Sherlock’s unique Engineering Biology platform advantages span virtually every important category of performance: Performance In addition, Sherlock’s technologies have advantages that can create value for existing and new applications. Sherlock’s platforms also deliver the following important attributes: Attributes Contact us to learn more about how we are engineering biology to test anywhere, everywhere. 617-612-8209 info@sherlock.bio Sherlock Biosciences 40 Guest Street, 3rd Floor Boston, MA 02135 © 2021 Sherlock Biosciences. All Rights Reserved. Sherlock uses your contact information to update you about Sherlock’s products and services. To learn more about how Sherlock treats your information, please review our privacy policy. Terms of Sale. We use cookies and by using this site or closing this message, you agree to our privacy policy. Allow Scroll to close this message.