Products Area of Interest Resources Support Company Careers Immunology Redefine immunology with multiomic single cell and spatial characterization Overview Multiomic Cytometry Resources Publications Products Download eBook Explore a new era of immunological discovery Every day, immunologists deepen our understanding of the immune system’s intricate network of responses and interactions. Learn how single cell and spatial multiomics are empowering exciting new research into autoimmunity, immuno-oncology, vaccine development, and beyond. Download Immunology eBook Critical Tools for Coronavirus (COVID-19) Research The ongoing COVID-19 outbreak has taken thousands of lives and the number of infections is growing daily. With single cell and spatial technology, you can capture multiple dimensions of infection and the immune response. Explore a curated list of COVID-19 publications and other helpful resources. View COVID-19 Resources Infectious Disease Uncover how pathogens infect host cells and elicit immune responses. Link the host immune response to infection recovery or severity. Learn More Autoimmunity Decipher the underlying mechanisms of misdirected immune responses. Explore the pathophysiology of disease in single cells and organ systems. Transplantation Advance clinical management of solid organ and hematological stem cell transplants. Understand the immunological basis for transplantation disease conditions. Therapeutic Discovery Define the receptor repertoire and antigen specificity of adaptive immune cells. Advance vaccine development, identify prophylactic antibodies, and generate targeted immunotherapies. Cellular and Molecular Immunology Explore the fundamental biology of the immune system in health and disease. Characterize immune cell identity, function, and organization in the body. Allergies and Inflammation Investigate the biology of innate and adaptive immune activation. Decode the mechanisms of immune hyperactivation in response to bodily insult or injury. Immuno-oncology Identify infiltrating immune cells within the tumor microenvironment. Characterize immune cell functions and receptor repertoire. Explore the immune system with multiomic resolution Enter this interactive technology exhibit from 10x Genomics to explore, compare, and understand how to integrate multiple cytometry techniques for immunology research. Experience Multiomic Cytometry Explore featured resources to enhance your immunology research On-demand Webinars Discover how researchers used multiomic cytometry to improve biomarker discovery by deeply characterizing cell types through the simultaneous analysis of cell-surface epitopes and intracellular mRNA-based gene expression parameter. View Webinar View All On-Demand Webinars Research Snapshots Explore how researchers used single cell analysis to study individuals with exceptionally long lifespans, and how they found that expansion of cytotoxic T cells may confer protection against cancer and viral infection. View Research Snapshot View All Research Snapshots Immunology Multiomics 101 From profiling immune cells in disease to understanding T-cell exhaustion, find guidance for your immunology research with this one-stop-shop resource for multiomic single cell experimental planning. Download the essential guide Publications Getting to the next level of characterization and resolution Immunologists around the world are leveraging 10x Genomics single cell and spatial products to advance our knowledge of the heterogeneity and developmental progression of immune cells. See how immunologists are taking their research to the next level by viewing our featured publications and downloading our Immunology Research Highlights flyer. Download Immunology Research Highlights Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome Nature Medicine, Jan 2020 Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses Science Immunology, Aug 2020 Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 Nature Medicine, May 2020 Products for Immunology Research Single Cell Immune Profiling Analyze full length paired BCRs/TCRs, surface protein expression, antigen specificity, and 5' gene expression in the same cell. Use single cell multiomics to discover new biomarkers, novel cell types and functions, and recover a comprehensive immune repertoire. Perform antibody discovery and immune receptor mapping, or combine it altogether. More info Single Cell Gene Expression Profile cell types and states with 3' gene expression, surface protein expression, and CRISPR perturbations in the same cell. Perform immune cell atlasing and deep characterization of cells using both cell surface markers and gene expression, identify cell state. Discover new biomarkers, and explore key regulators of immune activity with CRISPR screens. More info Spatial Gene Expression Spatially profile gene expression with morphological context in intact FFPE or fresh frozen tissue sections. Characterize immune cell infiltration or engineered T cells and activation/exhaustion state in the tissue microenvironment. Identify viral entry points. More info Single Cell Multiome ATAC + Gene Expression Explore combined gene expression and chromatin accessibility data from the same cell to uncover gene regulatory programs. Deeply characterize immune cell states, uncover gene regulatory programs driving immune cell lineage and differentiation. Identify target genes and cell types of genetic variants associated with immune-mediated disease. More info Redefine your understanding of innate and adaptive immunity View Products Contact Us ABOUT Products Platform Company Careers Contact Employment Verification LEGAL NOTICES Privacy Policy Terms of Use Email Preferences Other Legal Notices HEADQUARTERS +1 925 401 7300 +1 800 709 1208 info@10xgenomics.com RESOURCES Publications Support Videos SOCIAL SIGN UP FOR PRODUCT AND EVENT UPDATES Subscribe © 2021 10x Genomics. All Rights Reserved. English中文日本語