. | Skip to navigation Site Map About this site Contact Legal notice Cookies Search Subjects map Personal tools JOINT RESEARCH CENTRE EURL ECVAM Navigation path European Commission EU Science Hub EURL ECVAM Search Advanced Search… Featured article Review of the Availability of In Vitro and In Silico Methods for Assessing Dermal Bioavailability Read more... Watch our video! Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testing Transcripts: EN; FR; DE; IT. The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre located in Ispra, Italy. EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed. EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their application in industry and their acceptance by regulators. The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre. As from 2011, ECVAM's tasks are assigned to EURL ECVAM. The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site. To contact EURL ECVAM, please use this interactive form. Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012. highlights Advancing non-animal testing methods: first set of novel knowledge tools published - Sep 30, 2016 The Organisation for Economic Co-operation and Development (OECD) has recently published the first five adverse outcome pathways (AOP), three of which have been developed by the JRC. The AOPs are novel knowledge management tools in toxicology and are useful for supporting risk assessment to human health. They are also valuable for helping to avoid animal testing through the use of alternative methods. Assessing potential risks from exposure to chemical mixtures – JRC review of case studies - Jul 08, 2016 A review of case studies assessing the risk from exposure to chemical mixtures shows a potential concern for several groups of chemicals for highly exposed or particularly vulnerable population groups. A cross-sector review of the demand for in vivo carcinogenicity studies - Jun 29, 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre releases its report reviewing the current demand for in vivo carcinogenicity studies across chemical sectors within the European Union Summary records available for the meeting of EURL ECVAM with its stakeholders and regulatory advisory network - Jun 21, 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) has published the summary records for the meetings which took place with the members of the Preliminary Assessment of Regulatory Relevance (PARERE) network and the joint meeting of PARERE and the EURL ECVAM Stakeholder Forum (ESTAF) EURL ECVAM hosts meeting of European 3Rs Centres - Jun 08, 2016 On 31st May to 1st June 2016 the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre hosted a second meeting of European 3Rs Centres at the JRC site in Ispra (Italy). These European Centres focus on a variety of innovative ways for achieving impact in the 3Rs – the Replacement, Reduction and Refinement of the use of animals used for scientific purposes See all highlights calls EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) Supporting the validation and implementation of in vitro methods for regulatory use Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia Call for expressions of interest - EURL ECVAM Stakeholder forum (ESTAF) Open Invitation addressed to stakeholder organisations See all calls multimedia Toxicological Testing of Chemicals & EURL ECVAM Faces of Science - showcasing the human face of the scientific advice supporting EU policy. Maurice Whelan at the Joint Research Centre, the European Commission's in-house science service, presents the Toxicological Testing of Chemicals and EURL ECVAM New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods See all multimedia Navigation Home Latest News About EURL ECVAM EURL ECVAM Strategy Papers EURL ECVAM Recommendations EURL ECVAM Status Reports Validation & regulatory acceptance Test Method Submission EU-NETVAL Validation Laboratories Laboratories & Research Areas Databases Glossary Job vacancies EURL ECVAM's latest tweets Follow us @EU_ScienceHub #ECVAM #ChemicalsSafety Last update: Sep 30, 2016 Site Map About this site Contact Legal notice Cookies Search Subjects map Top