Search HomeCollectionsProtein Degrader Toolbox Protein Degrader Toolbox Ready-to-use tools for your discovery One of the most emerging therapeutics area focused on modulation of ubiquitin proteasome system (proteolysis targeting chimeras, PROTACs) is very much in need of new and robust chemistry. Booming biological assays in this field of drug development require production of dozens and hundreds of new bifunctional molecules. The time needed for production of new derivatives is crucial for any new project in this therapeutic area. To facilitate all further work on bifunctional linked molecules we have developed a stand-alone toolbox. This customized compound set was created from only in-stock intermediates and verified in-house chemistry to facilitate further production of new conjugates. We offer distinct tools that you can mix-up to design molecules of your special interest. The following options are available for synthesis of new molecules or immediate delivery to your research site: Ubiquitin ligases recognition ligands Orthogonal PEG-linkers and their carba-analogs Functionalized Warhead Ligands Active degraders Molecular Glues PROTAC related compounds in stock E3 functionalized ligands Cereblon ligands and ligands with linkers VHL ligands and ligands with linkers Orthogonal Linkers Molecular Glues Functionalized Warhead Ligands Active Degraders Glutarimides stock REAL CRBN Ligands CRBN Ligands for Clic Chemistry REAL VHL Ligands VHL Ligands for Clic Chemistry Request PROTAC related compounds in stock Events News Partners Posters Press Releases Blog Publications Press Kit Site Search Contact Us Follow us in social media: Cookies setting | Terms of use | Privacy policy Your choice regarding cookies on this site We use cookies to optimise site functionality and give you the best possible experience. AcceptManage Preferences

Search HomeOur Research RESEARCH Our Research & Development Department is committed to introduction of new methods and expeditious syntheses in heterocyclic, organofluorine and other chemistries. Experienced chemists direct their activity to the elaboration and synthesis of novel drug-like scaffolds and preparation of small libraries of substances based on these scaffolds. Most of these compounds are heterocyclic derivatives. Certainly, during the research we are dealling with scientific challenges, which are successfully solved by our experienced and creative scientists. We conduct our research in cooperation with research groups from various scientific centers in Ukraine and the most interesting results are published in international journals. As seen in Chemical & Engineering News, 2014 About us Our Research Publications Product Focus Posters Presentations News & Events Collaboration Blog Contact us Events News Partners Posters Press Releases Blog Publications Press Kit Site Search Contact Us Follow us in social media: Cookies setting | Terms of use | Privacy policy Your choice regarding cookies on this site We use cookies to optimise site functionality and give you the best possible experience. AcceptManage Preferences