Regional Sites Contact Us ORAL DOSE BIOLOGICS SPECIALTY CLINICAL SUPPLY CONSUMER EXPERT CONTENT LOCATIONS ABOUT US CAREERS Home » Expert Content » Oral Technologies EXPERT CONTENT Downloadable expert content covering integrated, tailored solutions to accelerate your path to market. VISIT OUR YOUTUBE CHANNEL BROWSE BY SITES: BIOLOGICS CLINICAL SUPPLY SERVICES CONSUMER HEALTH TOPIC: VIEW ALL DEVELOPMENT & BIOAVAILABILITY DOSE FORM DESIGN ORAL TECHNOLOGIES SOFTGEL TECHNOLOGIES ORAL MANUFACTURING SMALL MOLECULE ANALYTICAL INHALATION SMALL MOLECULE INJECTABLE TYPE: VIEW ALL ARTICLE BROCHURE CASE STUDY EBOOK EXECUTIVE SUMMARY INFOGRAPHIC OFFERING FACT SHEET VIDEO WEBINARS Using Zydis® ODT to Solve Delivery Challenges for Tolerogenic Vaccines Summary: Using Zydis® orally dissolving tablet (ODT) platform from Catalent as a unique delivery route for allergy immunotherapies. Biologics By Mouth-Leveraging Freeze-Dried Orally Disintegrating Tablets Summary: Learn more about the role of oral dose delivery for tolerogenic vaccines, fast dissolving tablets and biological APIs. Is My Molecule Suitable for an Orally Disintegrating Tablet? Summary: While new drug products may benefit from ODT formulation beginning with product launch, ODT formulation can also play a role in life cycle management of approved products. OptiForm® Solution Suite Bio Capabilities Sheet OptiForm® Solution Suite Bio is designed to rapidly screen biomolecules’ potential for a non-invasive delivery route. Exclusive Orphan Drugs Industry Survey Results Desire to Treat Rare Diseases Tempered by a Lack of Internal Expertise and Capability Summary: Orphan drugs face obstacles that span from discovery to launch, largely because of small patient populations and limited markets for rare disease therapies. Zydis® Orally Disintegrating Tablet (ODT) vs. Standard Tablets (ST) Summary: This infographic provides a high level summary of studies comparing Zydis ODT against traditional oral tablets. Is My Molecule Suitable for an Orally Disintegrating Tablet? Summary: This webinar aims to provide clarity on the types of molecules suitable for an ODT format as well as the regulatory pathways for new and established therapies. Amorphous and Co-Amorphous Systems for Poorly Soluble Drugs Summary: This webinar provides an overview of co-amorphous research and its recent findings, particularly, the impact of low molecular weight excipient on developability, stability and solubility. Getting Your Molecule From Preclinical Dev to Phase I Summary: Three early drug development experts present insights and techniques to help your clients get their molecules from preclinical to Phase 1 studies. Early Drug Development: Strategy and Solution This webinar focuses on the key considerations for transitioning small molecules from preclinical through clinical development. From Development to Commercialization: Overcoming Scale-Up Issues Summary: Recorded at Manufacturing Chemist Live 2020, this presentation discusses some of the key issues to consider when planning for the scale-up of a small molecule development program. Interview: Fierce Pharma with Jeremie Trochu Summary: Jeremy Trochu, Vice President and General Manager of Pharmaceutical Development Services at Catalent, recently sat down for an interview… OneXpress™: Phase Appropriate Technology & Expertise from Development to Commercialization Summary: OneXpress is a single integrated solution that provides the fastest pathway from clinical development to commercial manufacturing. By taking a proactive approach and assessing production considerations early in development, our teams… Early Phase Solutions Summary: Explore how you can leverage Catalent’s successful track record optimizing thousands of molecules, deep development expertise and broadest set of superior technologies to… Catalent Spray Drying Technology: From Development to Manufacturing Summary: Catalent offers end-to-end spray drying solutions from early-phase development through to clinical supply, and scale-up to commercial finished dose forms. Strategies to Avoid Dangerous Pitfalls in Pharmaceutical Consulting Summary: Learn the strategies to avoid costly pitfalls in pharmaceutical consulting and Gain inside tips on using CDMO’s to deliver solutions to your clients. Setting Up Your Small Molecule for Success: Formulation, PBPK Modeling and Regulatory Strategies in Early Clinical Trials Summary: This webinar focuses on the key considerations for transitioning small molecules from preclinical through clinical development. CMC Considerations for Successful Early Drug Development Summary: This eBook provides insights on key approaches and considerations for preparing your drug development program for long-term success. Phase Appropriate Expertise and Technologies to Accelerate Product Development to Commercialization Summary: In this webinar, pharmaceutical scientists present real-life examples of challenges they’ve overcome in the transfer of oral small molecules from early-phase development to late-phase manufacturing. Preparing Your Drug for Clinical Success: Strategies and Considerations Summary: View this webinar to learn about the key considerations for transitioning a molecule from discovery through clinical studies. Based on Exclusive Survey: Bioavailability Enhancement – Industry Insights, Key Challenges & Advanced Development Solutions Summary: In this webinar, experts present the exclusive survey findings and introduce innovative scalable drug delivery technologies proven to address the industry’s growing need for improving solubility and enhancing bioavailability. Spray Drying for Bioavailability Enhancement Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. Nearly 40% of the new chemical… How to Effectively Work with a Development Partner – From a Consultant Standpoint Summary: Hear from experienced industry colleagues on the latest tips that will help your clients avoid critical pitfalls in early development of their drugs to best leverage CDMO… Strategies for Flexible Manufacturing Summary: Pharmaceutical and biotechnology companies approach external development and manufacturing partners for solutions for their product’s specific needs. New products are increasingly… Proven Bioavailability Enhancement Solutions for Scalable and Robust Products Summary: Lipid formulation and spray-dried dispersions are widely used, and proven technologies to overcome bioavailability challenges for poorly soluble molecules. For selecting the… How to Accelerate Early Drug Development in Oncology For Small Molecules and Biologics Summary: Get an insight into what it takes to move a pre-clinical drug candidate to a Phase 1 clinical trial. The presentations will provide guidance on non-clinical and regulatory considerations… Spray-Drying Process for Scale up and Commercialization Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. In a recent Pharmaceutical… Prepare Your Clients for Success: Tips and Strategies to Avoid Dangerous Pitfalls in Consulting Summary: Determining a client’s primary goal is critical to guiding them through the development of their asset. Additionally, their primary focus will impact the strategy used to develop… Rapid Developability Assessment of Early Phase Molecules: Parallel Screening of Enabling Technologies and Use of PBPK Modeling Summary: Achieving success in early development is essential in progressing to your molecule’s next milestone. While solving solubility is a major hurdle to overcome in early development… All Offerings Summary: Catalyst + Talent. Our name combines these ideas. From drug and biologic development to delivery technologies and supply solutions, we are the catalyst for your… Planning for Successful Product Launches Summary: There has been increased focus and efforts on developing treatments for diseases with smaller patient populations, diseases for which there are no currently approved treatments… A Roadmap for Early Development to Commercial Manufacturing Summary: A key hurdle for any drug development program is bringing the drug to clinical studies. Astute companies strategize past this milestone and plan for clinical and regulatory success. Placing Patients at the Center of Drug Design Summary: Patient centricity has always been at the heart of the pharmaceutical industry. With rising costs of drugs and healthcare, there has been an increased focus on the topic. Poor patient acceptance and… Regulatory Support Summary: Our regulatory team completes over 150 agency submissions each year, supporting all stages of the product lifecycle. We assign a dedicated… How to Effectively Work with a Development Partner – From a Consultant Standpoint Summary: Determining a client’s primary goal is critical to guiding them through the development of their asset. Three experienced industry colleagues recently presented on the latest tips… Zydis® Oral Fast Dissolve | Why Catalent? Summary: The Zydis® ODT fast-dissolve formulation, is a unique, freeze-dried oral solid dosage form that disperses instantly in the mouth – no water required. With more than 20 products launched… Reliably Supplied | Why Catalent? Summary: We have the technology and expertise to take your product from design, to clinical trial, to plant, to pharmacy. Our global network of facilities can provide scalable, cost-effective… Catalent Zydis Fast Dissolve Summary: Zydis®, our proprietary fast-dissolve technology, is a unique, freeze-dried oral solid dosage form that disperses instantly in the mouth – no water required. With more than… Catalent in 30 Seconds Summary: With over 80 years serving the industry, Catalent is the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products…. Optimal Drug Delivery Technologies. Better Treatments. Summary: We are your catalyst for creating better treatments. Our deep expertise in drug development, delivery and supply can help improve the bioavailability of your compound, enhance therapeutic profiles… Catalent Corporate Overview Summary: Catalent is the global leader in development, delivery, and supply for pharmaceuticals, biologics, and consumer health products. Integrated analytical and clinical supply services support to… Unlock Your Molecules Potential with Catalent Summary: Your molecule has so much potential, we share the passion to unlock it through extensive expertise and superior formulation technologies. Learn how we have optimized thousands… Bring Pharma, Biopharma and Consumer Health Products to Market with Catalent Summary: A short video on how Catalent can help you develop, deliver, supply better treatments. Whether it is Pharmaceuticals, Biopharmaceuticals, Over-the-Counter, Nutritionals or Beauty Care and Cosmetics, we can… OptiForm® Solution Suite – Fast Track Early Development | Catalent in 90 Seconds Summary: Learn about a Fast, Flexible and Fact-based path for your molecule to progress from late-stage discovery to phase I. Zydis® ODT – Real World Solutions for Patients Summary: Zydis® ODT is an orally dissolving tablet formulated as for fast dissolve that requires little to no water when taking the medication. It provides an ideal dosing solution when dealing… Career Development at Catalent Summary: Catalent offers employees numerous opportunities for development and career progression. Hear more about what our team has to say about how Catalent supports their… Product Development Careers at Catalent Summary: Members of our product development eam gain unparalleled experience working on several products using multiple technologies. Hear what it’s like to work… Zydis® ODT Consistently Offers Effective Solutions for Sublingual Allergy Immunotherapy Summary: ALK-Abelló A/S is a Denmark-based pharmaceutical company that specializes in the development of immunotherapy products for the treatment of respiratory allergies. ALK partnered with Catalent for… Beyond HPLCs: Advanced Analytical Tools for the Development and Analysis of Drug Products Summary: Advanced analytical techniques can provide timely insights into a product’s stability, performance, and composition. Download this webinar to get expert insights on the applications of analytical techniques to help answer various questions… An Integrated Approach to Spray Drying – From Scale-up to Manufacturing Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. Nearly 40% of the new chemical entities (NCEs) screened by pharmaceutical… Unlock Industry Perspectives on the Advantages and Challenges of Developing Advanced Dosage Forms Summary: Watch the webinar to learn about the tools and technologies for creating dosage forms such as orally disintegrating tablets (ODTs), multi-particulates, and modified release formulations. Strategies To Develop Lipid-Based Drug Delivery Systems And Oral Dosage Forms Summary: Liquid-filled capsules (LFC) are the primary delivery platform for oral delivery of lipid formulations which includes both softgels and liquid-filled hard capsules. Liquid-in-bottle is… Overcoming Manufacturing Challenges For Accelerated Drug Development Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks.. ZYDIS® ODT Unlocks a Patient Preference for Rapid Onset in the Treatment of Migraine Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks.. Why Do New Therapies Succeed Or Fail In The Marketplace? How can decisions made during the preclinical phase of drug development increase the chances of a product’s eventual success in a difficult marketplace? Patient-Focused Drug Design – A View From The R&D Front Lines Summary: Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient outcomes. Lipid Workshop Part 1: Early Development With Lipids Get insights on using lipid systems during early development to achieve successful formulation and patient outcomes AAPS 2015 Posters Catalent’s experts presented technical posters on advanced drug design, discovery, development, delivery, packaging and scale-up. Click here to download [Part 1] of the 2015 AAPS posters Click here to… Designing Complex Release Oral Solids Controlled and Modified Release dosage form can improve patient experience. Elemental Impurities- Guidelines, Testing And Assessments This eBook published by Pharmaceutical Technology provides an overview of the regulatory landscape related to elemental impurities testing, discusses the challenges of implementing ICH Q3D guidelines … Commercial Scale-Up On Fluid Bed Wurster Coating You will learn about a pharmaceutical company who was interested in scaling-up a multi-particulate, modified-release product to a commercial scale using fluid bed bottom-spray (Wurster) coating. Softgel Technology For Fast-Tracked Development Programs Summary: Given the accelerated timelines associated with expedited programs, lipid-based drug formulations, encapsulated in softgel capsules, provide an attractive option for addressing the challenges… De-Risk Your Early Phase Programs Lipid based drug delivery systems (LBDDS) are the most studied and understood bioavailability enhancing solutions Elemental Impurities- Guidelines, Testing and Assessments Testing for elemental impurities in pharmaceuticals is a key risk assessment activity. This eBook published by Pharmaceutical Technology provides an overview… A View From The R&D Front Lines Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient outcomes. The Product Development Superhighway Pharmaceutical and biotechnology companies value streamlined services from early-phase development to clinical supply services to commercialization. Formulation Development for Scalability Lipid formulation and spray-dried dispersions are widely used, and proven technologies to overcome bioavailability challenges for poorly soluble molecules. Commonly Asked Questions About Elemental Impurities Read the latest article published by Pharmaceutical Technology giving an overview of elemental impurities testing and elemental impurities risk assessment process. Exploring Barriers and Facilitators to Drug Launch Success Understand why new therapies fail or succeed in the market place and learn when and how to apply advanced technologies to help increase the chance of success Value Creation in the Early Phase Strategies companies can use to succeed in both advancing their candidates and attracting investors Quality by Design Approach to Analytical Method Optimization Quality by Design (QbD) is well established in the pharmaceutical industry for manufacturing processes, including active pharmaceutical ingredients and drug products. Streamline Early Drug Development How to create a development strategy that bridges gaps earlier in the process to make the transition smoother. The Role of Roller Compaction in Dose Design Roller compaction is a popular dry granulation process with some significant advantages over wet granulation processes. Phase Appropriate Stability Studies Stability is a critical quality attribute of pharmaceutical products Formulation Design in Oral GLP Toxicology Studies Read this article and learn about focus areas in the early drug development process that are critical for a successful toxicology study. Scale-up of Wurster Process Learn more about Wurster Process at Catalent Winchester. Commercial Scale-Up on Fluid Bed Wurster Coating Read this case study on commercial scale-up on fluid bed wurster coating. Dysphagia Dose Design Gain more knowledge on dysphagia, which is one of the major factors affecting medication adherence and proper medication administration. PBPK Modeling and Other Strategies for Early Phase Success Leveraging knowledge about an API’s physiochemical properties from preformulation and formulation studies increases the chances of early-phase success. Overcoming Technology Transfer Challenges The key to a successful tech transfer is for the vendor and the contract manufacturer to anticipate the challenges and come up with a game plan for the solutions to potential challenges. Risk Assessment & Test Requirements for Elemental Impurities Selecting the best risk assessment and analytical testing strategy is key to successful compliance with the new regulations. Best Practices for Identifying Development Candidates The use of Pre-clinical tools to study pharmacokinetics, choose a lead drug candidate and move that product into development. Putting The Patient First When Manufacturing OSD Forms Expert insights on ODT challenges and solutions from European Pharma Manufacturing. Technical Guide for Solid Dispersion Development Get the steps involved in the development and manufacturing of an ASD via the spray drying process. The Formulation Complex Tips and advice on overcoming the most common formulation mishaps and why beginning with the end in mind is crucial. From Candidate to Clinic Strategies to Select, Assess, Formulate, and Deliver the Right Drug Candidate in the Early Phase. Dose Selection Using Preclinical PK Modeling How pre-clinical tools used in the industry to study pharmacokinetics are used to guide the development of new chemical entities (NCEs). Design & Formulation for GLP Toxicology Studies Evaluate critical areas in the drug development process to help ensure a successful toxicology study. Review and Analysis of FDA Approved Drugs Using Lipids A review and quantitative analysis of the molecular properties of approved drugs formulated as lipid systems Bioavailability Enhancement Through Spray Dried Dispersions The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility. Bioavailability Enhancement through Spray Dried Dispersions The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility. Designing Complex Release Oral Solids Controlled and Modified Release dosage form can improve patient experience. Tech Talks with Catalent – Spray Drying Technology Successful spray drying process for clinical and commercial production. Smart Drug Development & Design from Candidate to Phase I Key considerations for transitioning a molecule from discovery to phase 1 readiness Data-Driven Approach to Overcome Bioavailability Challenges Unbiased & data-driven approach to select bioavailability enhancement technology. Solid Dose Trends How the industry’s most stable drug form is innovating and evolving to stay relevant. Formulating Candidates with Bioavailability Issues How formulation screening early in the process can reduce development timelines. Improve Patient Experience and Therapeutic Outcomes Advanced formulation and drug delivery technologies for patient-centric drug design. Developing Oral Dosage Forms Agnostic & data-driven approach for early stages to find optimal formulation technology Orally Disintegrating Tablets- A Patient-Centric Dosage Form Discover how orally disintegrating tablets (ODTs) can be both patient friendly and offer numerous formulation advantages. Oral Delivery of Macromolecule Drugs for Localized Treatment Latest formulation approaches on enabling oral route for macromolecule drugs for local treatment. Early-Phase Pharmaceutical Development Strategies Insight on early development, characterizing solid state forms and first-in-human strategies. Preclinical & First-in-Man Drug Development Strategies Methods for developing a sound, phase-appropriate formulation for early development. ODT: A Patient-Centric Dosage Form Discover new developments in ODT technology including delivery of peptides and vaccines. Improve Your Phase I Success Rate A parallel formulation feasibility assessment approach to enhance bioavailability. Overcome Barriers to Non-invasive Delivery Of Macromolecules Innovative, integrated approach to rapidly screen biomolecules potential for oral delivery. AAPS 2016 Presentations Discover the latest solutions and advancement in drug delivery technologies. A Dosage Form Designed for Difficult Patient Populations Explore how orally disintegrating tablets (ODTs) provide an alternative to overcome several challenges. A Holistic Approach for Drug Development and Delivery How can a patient-centric outlook help scientists tackle the key challenges of early drug development. Unlock Oral Delivery Potential for Macromolecules Effectively evaluate the potential of peptides and macromolecules for oral delivery. Innovative Drug Delivery Technologies for Better Treatments Better patient treatments fueled by innovations in lipid formulations. How Parallel Development with Proven Technologies Improves Efficiently and rapidly overcome complex bioavailability challenges for early stage molecules. Enhance Bioavailability with Parallel Screening Technologies Characterize molecules, apply right prediction model, & select ideal delivery technology. The Versatile Orodispersable Tablet (ODT) Technology ODT platform ideal for sublingual delivery of proteins, peptides & vaccines. Oral Dose Development of Macromolecules Discover new approach to optimize oral dose development for macromolecules. Optimal Formulation Technology for Better Patient Treatment Strategies for oral formulation selection which can lower attrition rates and more. Graphicaps™ Inline Printing Differentiate products at the unit dose level & deliver a more recognizable product. The Next Generation ODT New developments in ODT technology, including new ways to administer peptides & vaccines. Parallel Screening for Non-Invasive Macromolecule Delivery Integrated solutions to rapidly screen biomolecules potential for non-invasive delivery route. Strategies To Overcome Development Challenges Address development challenges early on and improve a drug’s path to market. Accelerate Development for Challenging Compounds Leverage solid dispersion & particle size reduction technology to enhance bioavailability. Optimizing API Properties And Formulation Utilize particle size reduction and formulation technologies to optimize the API. Novel Technologies To Deliver Oral Oncology Therapies Select optimal formulation technology to enhance therapeutic performance & patient experience. Create Effective Fast-Dissolving Oral Formulations Successfully manufacture oral dosage forms that disperse within 3 seconds & are enjoyable. The Medicine Maker – The Toolbox of 2025 Overcome therapeutic challenges and be prepared for years to come. Oral Formulation Strategies and Technologies Oral dose development with optimal therapeutic performance. Bringing a Small Molecule to Clinic Transition from preliminary formulation to commercial drug launch, quickly & cost-effectively. Pharmaceutical Abuse Deterrent Capsule Formulations Develop liquid capsule fill formulations that are mitigated to prevent abuse. New Approaches for Macromolecule Oral Delivery The toolkit of technologies based upon lipid-based drug delivery systems. OptiGel Bio Enables Delivery of Synthetic Oligosaccharides Macromolecules can potentially be converted from injectable to oral drug delivery. Expert Content Subscribe Investors Careers Contact Us Site Map Follow Us. Share Us. 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