Menu HOME > SOLUTIONS > INFORMATICS > PATIENT TECHNOLOGY > MEDICAL IMAGING > THERAPEUTIC EXPERTISE > ONCOLOGY IMAGING EXPERTISE > CRITERIA EXPERIENCE > 2007 IWG-NHL > KEY TOPICS: 2007 IWG-NHL ASSESSMENT CRITERIA > DEFINING NORMAL, ABNORMAL AND ... OFFERED BY KEY TOPICS: 2007 IWG-NHL ASSESSMENT CRITERIA INCORPORATES KEY TOPICS: 2007 IWG-NHL ASSESSMENT CRITERIA SOLUTIONS DEFINITIONS USABLE CRITERIA TO EVALUATE TARGET SITES OF DISEASE NON-TARGET SITES OF DISEASE ORGANOMEGALY NEW LESIONS BONE MARROW OTHER LABORATORY VALUES AND SYMPTOMS INCORPORATION OF FDG-PET DEFINING NORMAL, ABNORMAL AND MEASURABLE PROBLEM WITH CRU At baseline, nodal sites are considered abnormal and measurable when visible and/or palpable, attributable to lymphoma and when they measure >1.5 cm in longest diameter (LDi) or >1.0 cm in shortest diameter (SDi). Nodes which are both ≤1.5 cm in longest diameter (LDi) and ≤1.0 cm in shortest diameter (SDi) are considered normal and not part of the disease burden. Since nodal sites may never fully disappear, defining a normalization value is essential to correctly defining response. Large nodes (>1.5 cm in longest diameter (LDi)) must decrease in size such that the LDi is ≤1.5 cm to be considered normal. Small nodes (LDi >1.0 cm but ≤1.5 cm with a SDi >1.0 cm) must decrease in size such that the SDi ≤ 1.0 cm (the LDi must also remain ≤1.5 cm) to be considered normal. Extranodal sites are abnormal when either visible on imaging or palpable on physical exam. Extranodal sites must be absent for Complete Remission. All sites reported as disease should be attributable to lymphoma. DEFINITIONS USABLE CRITERIA TO EVALUATE TARGET SITES OF DISEASE NON-TARGET SITES OF DISEASE ORGANOMEGALY NEW LESIONS BONE MARROW OTHER LABORATORY VALUES AND SYMPTOMS INCORPORATION OF FDG-PET PROBLEM WITH CRU DEFINITIONS USABLE CRITERIA TO EVALUATE TARGET SITES OF DISEASE NON-TARGET SITES OF DISEASE ORGANOMEGALY NEW LESIONS BONE MARROW OTHER LABORATORY VALUES AND SYMPTOMS INCORPORATION OF FDG-PET PROBLEM WITH CRU LINKEDIN UPDATES VIEW PROFILE CAREERS AT PAREXEL® If you are inspired to make a difference in the world, we can help you make it possible. Search job openings worldwide PAREXEL International Corp. +1 781 487 9900 195 West Street Waltham, MA 02451 ABOUT PAREXEL® NEWS & EVENTS VOLUNTEER CONTACT MY PAREXEL PREFERENCE CENTER CLIENT LOGIN LIQUENT® CLINICAL TRIAL INVESTIGATOR SITE MAP TERMS OF SERVICE PRIVACY POLICY EU-U.S. AND SWISS-U.S. PRIVACY SHIELD NOTICE OF CERTIFICATION Copyright ©2000-2018 PAREXEL International Corporation.