Clinical Trials at Cardiology Associates Medical Group Clinical trials help doctors and researchers investigate whether new therapies or treatments are safe and/or better than those that already exist. Trials may explore treatments (medicines or surgeries), quality of life (making life better for people living with a disease or a health condition), preventative measures (medicines, lifestyle changes, or vaccines), or screening modalities (ways to detect or diagnosis disease). Clinical trials may benefit patients by offering treatments that are not currently available. While medical science develops new therapies that will benefit patients in the future, clinical trials may offer patients who are already battling a disease the opportunity to engage in a treatment that would currently be unavailable. The long term impact of clinical trials lies in their role in advancing medical science, thus empowering physicians to help develop new treatments or procedures. Clinical trial protocols are regulated by the U.S. government. During participation in the trials, patients are carefully monitored for side effects and to ensure that protocols are followed. All study results are carefully reviewed and documented in an unbiased fashion. Since its founding, Cardiology Associates Medical Group has actively participated in many clinical trials. Our physicians and staff are bound by the belief that we are advocates for our patients’ care. Advancing medical science by helping to develop new and effective treatments that will improve patient care and prevent cardiovascular disease is a cornerstone of our mission. Current Research Trials: EchoCRT, Biotronik, Inc. The EchoCRT trial evaluates the effects of Cardiac Resynchronization Therapy (CRT) on mortality and morbidity of subjects with heart failure due to left ventricular systolic dysfunction, already receiving optimized HF medication, with a narrow QRS width (< 130 ms) and echocardiographic evidence of ventricular dyssynchrony. This study is currently recruiting participants. ClinicalTrials.gov Identifier: NCT00683696 View Details Citadel, TyRx, Inc. The purpose of this study is to compare the incidence of cardiac rhythm management device (CRMD) infection and CRMD mechanical complication after CRMD replacement with an Implantable Cardioverter-Defibrillator (ICD) and AIGISRx Anti-Bacterial Envelope, to the incidence after replacement with an ICD and no AIGISRx. This study is currently recruiting participants. View Details ClinicalTrials.gov Identifier: NCT01043861 View Details IMPACT, Biotronik, Inc. The IMPACT Study will investigate the potential clinical benefit of the combined use of BIOTRONIK Home Monitoring (HM) technology and a predefined anticoagulation plan compared to conventional device evaluation and physician-directed anticoagulation in patients with implanted dual-chamber defibrillators or cardiac resynchronization therapy devices. This study is currently recruiting participants. ClinicalTrials.gov Identifier: NCT00559988 View Details Shock-Less, Medtronic, Inc. The purpose of this clinical trial is to determine whether periodic therapy programming reports illustrating physician usage of shock reduction programming can increase utilization of recommended programming guidelines for defibrillators. This study is ongoing, but is not recruiting participants. ClinicalTrials.gov Identifier: NCT00856349 View Details Citadel, TyRx, Inc. The purpose of this study is to compare the incidence of cardiac rhythm management device (CRMD) infection and CRMD mechanical complication after CRMD replacement with an Implantable Cardioverter-Defibrillator (ICD) and AIGISRx Anti-Bacterial Envelope, to the incidence after replacement with an ICD and no AIGISRx. This study is currently recruiting participants. ClinicalTrials.gov Identifier: NCT01043861 View Details Centurion, TyRx, Inc. The purpose of this study is to compare the incidence of cardiac rhythm management device (CRMD) infection and CRMD mechanical complication after CRMD replacement with a cardiac resynchronization therapy device (CRT) and AIGISRx Anti-Bacterial Envelope, to the incidence after replacement with a CRT and no AIGISRx. This study is currently recruiting participants. ClinicalTrials.gov Identifier: NCT01043705 View Details FLEXION, St. Jude Medical To demonstrate that ablation with the Therapy™ Cool Flex™ Irrigated Ablation System is effective in the treatment of typical atrial flutter (cavo-tricuspid dependent) and that its use does not result in an unacceptable risk of intra-procedural, serious cardiac adverse events. This study is ongoing, but is not recruiting participants. ClinicalTrials.gov Identifier: NCT01408485 Quadripolar Pacing Post Approval Study, St. Jude Medical The purpose of this post approval study is to evaluate the acute and chronic performance of a Quadrapolar CRT-D device system in a patient population indicated for cardiac resynchronization therapy. This study is currently recruiting participants. ClinicalTrials.gov Identifier: NCT01555619 View Details Ventura 168 North Brent Street Suite 503 Ventura, California 93003 Tel: (805) 653-0101 Fax: (805) 643-6285 Oxnard 1701 Solar Drive, Suite 150 Oxnard, California 93030 Tel: (805) 278-4020 Fax: (805) 278-4015 Community Memorial Hospital St. John Regional Medical Center Ventura County Medical Center Ojai Valley Community Hospital Cardiology Associates - © 2021