MyCELLINKSupport servicesContact us English OUR PRODUCTS OUR SCIENCE YOUR RESEARCH OUR EVENTS OUR STORY SHOP Get a quote 0 INTRODUCTION Bioinks are materials used to generate 3D tissue constructs using bioprinters. A bioink can be any natural or synthetic polymer selected for its biocompatible components and favorable rheological properties. These characteristics temporarily or permanently support living cells to facilitate their adhesion, proliferation and differentiation during maturation. CELLINK offers a wide range of bioinks with optimized formulations that ensure the viability of cells before, during and after the bioprinting process. SUPPORTING VIABILITY AND PROLIFERATION It is critical that the cells remain viable when blended within the bioinks during and after the printing process. An ideal bioink provides binding sites for cells while promoting their own extracellular matrix (ECM) production and ultimately help in generation of a functional tissue. FINE-TUNING THE VISCOELASTIC PROPERTIES Besides excellent bioactive properties, the second most important aspect in bioink development is printability to ensure that the ink can be extruded through a printing nozzle or needle into filaments while maintaining the shape fidelity and hierarchical deposit of the printed cells in 3D. Ideal rheological properties depend on the method used for generating 3D constructs. For example, extrusion-based bioprinting requires more gel-like bioink whereas droplet-based bioprinting can be achieved with more liquid-like bioinks. Characterization of the rheological properties is typically performed using a temperature-controlled rheometer. Eventually, new formulations need to be tested using a 3D bioprinter such as the BIO X or BIO X6. THE IMPORTANCE OF CROSSLINKING The process of crosslinking results in a shift from a rather viscous printable material to a more elastic material that provides and maintains structural rigidity. Crosslinking is commonly done by self-assembly, thermal gelation, UV light induction or by adding an ionic solution. Our bioprinters such as the BIO X come with a variety of different modules to facilitate crosslinking in a rapid and controlled manner. RELATED PUBLICATIONS 3D BIOPRINTING | INKREDIBLE | 01/17/2020 Polypeptide templating for designer hierarchical materials BIOINK | INKREDIBLE+ | 12/27/2019 Characterization and printability of Sodium alginate -Gelatin hydrogel for bioprinting NSCLC co-culture 3D BIOPRINTING | INKREDIBLE+ | 09/11/2018 Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus. RELATED PRODUCTS BIO X™ The most user-friendly bioprinter in the world thanks to its open system, intelligent and interchangeable printheads. Assists in developing complex tissue constructs, testing new drug compounds and streamline workflows in a range of application areas. READ MORE INKREDIBLE+ A pneumatic-based extrusion bioprinter with dual printheads and a UV LED curing system. It’s a cost-effective unit that enables innovators to enter the 3D bioprinting field and print living tissues at ease. READ MORE BIO X6™ The BIO X6 is the only true benchtop bioprinter to combine six printheads with our patented Clean Chamber Technology in a compact package, taking up a 78.1-cm footprint in your lab. READ MORE SUPPORT Series Our SUPPORT Series includes bioinks designed to support constructs and demonstrations. These bioinks incorporate thickeners, sacrificial materials and bright colors to make tailored architectures and educational projects easier than ever. READ MORE Keep up with the latest news by signing up to our newsletter SUBSCRIBE Contact us U.S. +1 (833) 235-5465 EU. +46 31-12 87 00 sales@cellink.com Navigation Our products Our science Your research Our events Our company Careers Privacy policyCookie policySite Map FacebookInstagramTwitterLinkedIn CELLINK 2021, All rights reserved.