Clinical settings Products Customer care Knowledge center About us Contact MyRadiometer Customer login Acutecaretesting.org Home > Webinars > The Benefit of Using a D-dimer Assay with a High Clinical Specificity The Benefit of Using a D-dimer Assay with a High Clinical Specificity November 29, 2016 Webinar presented by Karin Strandberg, MD, PhD, Assoc. Prof, Consultant, Labmedicine, Skåne, Sweden Playback Slides About this webinar D-dimer can be used to exclude venous thromboembolism (VTE) in outpatients. Together with a low pretest probability for VTE, a negative D-dimer can safely rule out VTE in 30-50 % of patients with suspected VTE. To date, there is no standardisation of D-dimer tests, which causes variation in results among methods. This webinar will discuss pitfalls and limitations of the D-dimer analyte with special focus on the performance differences among methods. The use of D-dimer requires a method with particular performance characteristics, most importantly: A high sensitivity and negative predictive value (NPV) to ensure that patients with VTE are not falsely characterized as ”not sick” Acceptable diagnostic specificity to minimize the number of radiological imagings on patients without VTE Good reproducibility around the cut-off (decision limit) to ensure reproducibility of whether a result is ”positive” or ”negative”. A verification of the performance of the assay in the local clinical population is also recommended, but it is a difficult and time-consuming task. Publications on comparisons between methods are therefore sometimes used to support the choice of method and the cut-off. Besides a sensitivity and negative predictive value (NPV) as close to 100 % as possible, a high specificity is of importance to limit the number of unnecessary radiological imagings for the benefit of the patient and to improve logistics and lower the costs of the health care costs. Who should attend? ED doctors and nurses Respiratory doctors Lab managers POC managers Cardiologists ICU doctors Operation theater doctors and nurses Continuing education US participants: One PACE® credit will be provided for each session Each session is approved for 1 Florida CE credit Florida Board of Clinical Laboratory Personnel approved number: 50-12563 International participants: A Certificate of Attendance will be available for all sessions for international participants to submit to their appropriate accrediting agencies Note: You can now join Webex Event Center from iPhones, iPads, and Android devices. Visit the Apple Store or Google Play to install the latest free app on your device. Knowledge website Check out the new acutecaretesting.org knowledge site or sign up for the quarterly acutecaretesting.org newsletter Learn more Legal notice | Use of cookies | Contact Radiometer Products ABL800 FLEX analyzer ABL90 FLEX analyzer ABL90 FLEX PLUS analyzer AQT90 FLEX analyzer safePICO PICO CLINITUBES Products TCM5 FLEX monitor TCM5 BASIC monitor TCM 400 monitor AQURE HemoCue Glucose Systems HemoCue Hb Systems Quality Control Solutions NICUs Emergency Departments Sepsis detection POC analyzer solutions Handbook, apps and guides Acute care testing handbook Preanalytical blood gas handbook Hemocue's my blood donor app Blood gas analysis video guides What is blood gas? Recent webinars Diagnosis and monitoring of sepsis: Lactate and beyond Benefit of using a D-dimer Assay with High Clinical Specificity Blood Conservation at the POC How can we help? Contact Radiometer Medical This is Radiometer Medical's global website and may contain information on products not released in all markets. For reference on specific blood gas testing solutions, immunoassay testing, transcutaneous monitoring, samplers, POC data management systems, QC and services available in specific markets, please go to your local Radiometer country website. HemoCue is part of the Radiometer Group. Find out more about HemoCue hematology and diabetes products on Hemocue.com. Browser compability: This website is best experienced using Microsoft IE 8.0+, Firefox 5.0+, Safari 5.0+, Google Chrome 12.0+. Older versions of these browsers and/or other browsers may not display content correctly. © 2017 Radiometer Medical ApS | Åkandevej 21 | DK-2700 | Brønshøj | Denmark | Phone +45 38 27 38 27 | CVR No. 27509185 Select your local site Argentina Australia Belgium Brazil Canada Chile China Colombia Czech Republic Denmark France Germany Hungary India Ireland Japan Luxemburg Malaysia Mexico Middle East and Africa Netherlands New Zealand Peru Poland Portugal Russia Singapore South Africa Spain Switzerland Turkey United Arab Emirates United Kingdom USA Cookies are used on this website Use of cookies Don't show this message again