Products Coffalyser.Net MLPA Procedure Support Ordering About us my products my Coffalyser.Net my profile login MLPA® is a rapid, high-throughput technique for copy number quantification and methylation status analysis of genomic sequences. MRC-Holland offers hundreds of MLPA® probe sets. Applications include: Congenital & Hereditary Disorders Tumours Profiling Methylation profiling Quantification of mRNA Online learning materials about MLPA Dear customer, As you probably are aware of, MRC-Holland frequently offers MLPA workshops to train customers in the use of MLPA. These workshops have proven to be very successful, but we can only train a limited number of customers. Therefore, to reach a broader audience, we are busy to create learning materials that will become available on our website. With these learning materials, customers can increase their knowledge about MLPA. Although we have great ideas ourselves, we are also very interested in what our customers look for when they want to learn about MLPA. We are in particular interested in information about the following: What topics do you like to be seen covered, Which knowledge level should the information should have (e.g. novice, mid-level, advanced), Would you like to incorporate the training materials in your laboratory training? If you train colleagues in MLPA, are you willing to share your experiences with this? Please e-mail your thoughts, ideas and suggestions to info@mlpa.com. Data sheets for Excel based Coffalyser not generated any more From 15 April onwards, the Excel based version of Coffalyser is no longer supported. This also means that the .txt analysis sheets are not generated anymore. We recommend to all our customers stepping over to the Coffalyser.Net, which is a free MLPA data analysis software created by MRC-Holland. Coffalyser.Net can support the entire MLPA workflow, from experimental setup to result interpretation using advanced charts and reporting tools. Coffalyser.Net supports input files that come directly from capillary systems (Applied Biosystems and CEQ by Beckman Coulter). The software contains a direct link to the MRC-Holland database allowing users to download all relevant MLPA probemix content directly into the software. The Coffalyser.Net program can easily be downloaded from this website free of charge upon registration. For people new to Coffalyser.Net, the Coffalyser Wordpress site offers the best introduction: http://coffalyser.wordpress.com. MLPA workshops this year To increase your understanding of MLPA, MRC-Holland organizes one-day MLPA workshops. The following workshops are currently organized and planned: National Harbor (Washington DC) - 11 November (prior to the annual AMP meeting) - When making a registration before September 26, an early bird fee of 95 Eur / 125 USD is applicable. Program MLPA raw data evaluation and troubleshooting Demonstration of MLPA raw data and peak pattern analysis using examples from daily practice. Instruction on how to recognise and solve common problems. Theory into Practice: MLPA troubleshooting Several cases of problematic MLPA experiments are analysed by the participants. Enhance your MLPA workflow Demonstration of the basic principles of MLPA data normalization with Coffalyser.Net software. Lunch Theory into Practice: MLPA data analysis Participants perform MLPA data analysis on a diverse set of MLPA data. Critical points in the analysis, such as selecting the optimal normalisation procedure and selecting reference samples, will be illustrated in practice. Advice will be given how to get the most out of your MLPA data. For Whom? A basic understanding of the MLPA technique as well as hands-on experience with MLPA is required. Experience with Coffalyser software is not required. All workshops will be held in English unless stated otherwise. Registration The registration fee for this workshop is 129 euro per person. This fee covers documentation, lunch and refreshments. The fee does not include travel or accommodation costs. If you are interested to participate in our workshops, please send an e-mail to info@mlpa.com. You will then receive more information how to register. We are looking forward to meet you at our workshops! Most critical points in performing MLPA experiments "My MLPA peak patterns are of low quality. What can I do to improve them and make my results more reliable?" You can find a list of the most important factors that contribute to a successful MLPA experiment here. Subscribe to our newsletter Subscribe here to our periodic newsletter to receive the latest information about our products, technology and website. You can unsubscribe anytime. MRC-Holland is ready to hit the road! With our new booth made by Expo Display Service delivered, MRC-Holland is ready to hit the road to attend several meetings in the United States. If you are attending one of the following meetings, please stop by our booth to learn more about how MLPA can be used to benefit your DNA, RNA or methylation analysis. October 18-22 - Annual American Society of Human Genetics Conference 2014 - San Diego, CA The annual meeting of the ASHG is organised in sunny San Diego. Please visit our booth #1031. For more information about this conference, please visit the website of the ASHG: ASHG.org November 13-15 - Association for Molecular Pathology (AMP) 2014 Annual Meeting - National Harbor, MD This year the annual conference of the AMP will be held in National Harbor, just outside of Washington, DC. Please visit our booth #229. For more information about this conference, please visit the website of the AMP: AMP.org December 6-9 - Annual meeting of the American Society of Hematology (ASH) - San Francisco, CA The 56th annual meeting of ASH will be held in San Francisco, known for the Golden Gate Bridge and its steep rolling hills. Come and meet us at booth 1747 to ask all your questions about MLPA applications on hematologic conditions. For more details about the conference, please visit the ASH website hematology.org new products P453-GAA Pompe Disease P380-Wilms' tumour Wilms' tumour P446-GALC Krabbe Disease P063-FHIT-WWOX FHIT-WWOX improved products P193-NPC1 Niemann-Pick type C disease (NPC) P269-FRMD7 Congenital nystagmus P209-Glycine Encephalopathy Glycine encephalopathy P075-TCF4-FOXG1 Pitt-Hopkins syndrome, Congential variant of Rett syndrome P337-TSC2 Tuberous sclerosis P228-TRPS1-EXT1 Trichorhinophalangeal syndrome type I (TRPS1), Langer-Giedion syndrome (LGS) Newsletter | Home | Site map | Terms and Conditions | Search | Copyright © 2014 MRC-Holland