About Us Contact Us Resources News & Events Technical Support Careers Applications Products Services Life Cycle Process Science Home • Life Cycle • Development • Process Science • Robust process development is a key responsibility of any pilot plant and can enable quick and efficient scale-up to commercial manufacturing. The rapid non-destructive headspace platforms from LIGHTHOUSE have revolutionized process studies by enabling the straightforward analysis of statistical samples sets, or even whole batches. LIGHTHOUSE provides full insight into process quality and robustness and our automated headspace analysis platforms can be delivered within weeks for project-based process studies in which full batches are inspected.. Characterizing N2 Purging Systems for Liquid or Powder Filling Lines Characterizing Freeze Dryers and Cappers for CCI Characterizing Freeze Dryers for Moisture Distribution Characterizing N2 Purging Systems for Liquid or Powder Filling Lines It is critical to limit the exposure of sensitive formulations to oxygen. LIGHTHOUSE headspace analysis platforms can be set up at- or in-line to a filling line to monitor headspace oxygen levels and the performance of nitrogen purging during filling. Real-time feedback can be invaluable for optimizing and validating the N2 purging process. As with all LIGHTHOUSE systems, the rapid nature of the measurement means statistical sample sets (and even full batches) can be quickly analyzed, and because the measurement method is nondestructive, there is no need to dispose of destroyed product samples. In Process Monitoring of Headspace Oxygen Poster: Characterizing and Optimizing Parenteral Manufacturing processes Nitrogen Purge Optimization & Validation FMS-Oxygen Headspace Analyzer Webinar: Protecting Oxygen Sensitive Formulations Characterizing Freeze Dryers and Cappers for CCI LIGHTHOUSE has characterized over 15 million commercial freezed dried pharmaceutical vials for container closure integrity (CCI) from sterile manufacturing facilities around the world. Both the freeze drying and capping processes can introduce risk into the container closure integrity of sterile freeze dried product vials. Our container closure integrity inspection applications quantifies this risk and supports your pharmaceutical process development. Stopper "Pop-Up" effects on CCI of Freeze Dried Vials Poster: Characterizing and Optimizing Parenteral Manufacturing processes FMS-Oxygen Headspace Analyzer White Paper: 100% Container Closure Integrity Testing PULSAR Lease System: 100% CCIT Characterizing Freeze Dryers for Moisture Distribution The use of LIGHTHOUSE platforms for the non-destructive measurement of headspace moisture levels in lyophilized pharmaceutical product enables efficient and insightful lyophilization process studies. Analyzing statistical sample sets, and even full batches, enables deep insight. This insight includes moisture mapping of the lyo chamber for freeze dryer qualification and full visibility into moisture variability within a batch for lyo cycle optimization and validation. Case Study: Lyo Chamber Moisture Mapping FMS-Water Activity Analyzer Webinar: Non-Destructive Moisture Analysis of Freeze Dried Product White Paper: Moisture Determination of Freeze Dried Product PULSAR Lease System: 100% CCIT FMS-Pressure/Moisture Headspace Analyzer Poster: Characterizing and Optimizing Parenteral Manufacturing processes Quick Links APPLICATIONS Container Closure Integrity Testing Oxygen Monitoring Water Activity Determination Moisture Determination PRODUCTS Automation Laboratory Instruments SERVICES Lab Testing On-site Testing Equipment Lease LIFE CYCLE Development Manufacturing Quality Control Contact Us Wherever you need support optimizing product and process quality throughout the product lifecycle, LIGHTHOUSE experts are available for you. Request Info Corporate Headquarters 2050 Avon Court Charlottesville, VA 22902 Telephone: +1 (434) 293-3081 E-mail: info@lighthouseinstruments.com European Support Center Science Park 408 1098XH Amsterdam The Netherlands Telephone: +31 20 7051 050 E-mail: euinfo@lighthouseinstruments.com Site Map | Cookie Policy | Privacy Policy | Terms of Use Subscribe to our newsletter Sign up to receive information on headspace analysis applications, industry updates, webinars and other events. Select your application area of interest below: LIGHTHOUSE © 2021 | Website created by Advanta Advertising, LLC We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok