about camurus news products technologies partnering contact technologies FluidCrystal® Injection depot Camurus' FluidCrystal® injection depot delivers therapeutic levels of drug substance over extended periods - tunable from days to months - from a single injection! While traditional depot therapeutics comprise complicated microsphere technology, Camurus' depot offers a liquid solution that transforms into a controlled release liquid crystal gel matrix in situ on contact with minute quantities of aqueous fluid at site of injection. The FluidCrystal® injection depot overcomes traditional side effects associated with high initial drug release on injection (drug burst), poor drug stability and complex processing requirements by effectively encapsulating the drug compound in the nanopores of the depot matrix, throughout the entire process from injection until final degradation. This makes the system highly suitable for sustained parenteral delivery of peptides and potent small molecule drug compounds. The release duration can be tuned to meet dosing frequency specifications ranging from once-daily to once-weekly or once-monthly. In special cases even longer duration of up to three months is feasible. Products are ready-to-inject Manufacturing of products based on Camurus' depot technology involves just a few standard pharmaceutical processing steps. Products are ready to inject, without the need for complicating reconstitution and mixing steps, thus making them ideal for prefilled syringes or other injection devices. The low viscosity of our injectable formulations permits the use of very thin needles. 23 to 27 gauge is standard, so there is less pain on injection. Key competitive advantages True ready-to-inject product design Subcutaneous, intramuscular or intracavital administration Small needle size; 23-27 gauge Low burst and consistent release Tunable duration from days to months Demonstrated safety in clinical trials Simple manufacturing by standard processes Low cost of goods Strong intellectual property Subcutaneous injection of lipid-based formulation Formation of liquid crystal gel by absorbtion of water (w) Slow release of drug (D), biodegration of depot › FluidCrystal® Topical bioadhesive Camurus' FluidCrystal® topical bioadhesive delivery technology is a film forming formulation providing local and sustained release of drug compounds administered topically. The delivery system is suited for delivery of peptide and small molecule drug compounds to dermal, buccal, ophthalmic, nasal, vaginal, and other topical biosurfaces. It also provides good temporary protection of sore, sensitive mucosa. › FluidCrystal® Nanoparticles Camurus' FluidCrystal® nanoparticle delivery technology is addressing bioavailability limitations for amphiphilic and lipophilic drugs with low aqueous solubility or biodegradation sensitive drugs such as peptides and proteins. The delivery system is available either as a non-aqueous precursor formulation which self-disperses to nanoparticles in contact with water or as aqueous nanoparticle dispersions for parenteral, transdermal or oral applications. › › UP Innovative nanoscale therapeutics © 2014 Camurus AB home about camurus news products technologies partnering career press contact This website contains information on products which is targeted to a wide audiences and could contain details or information other wise not accessible or valid in your country. Please be aware that we do not take any responibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your region. legal notice privacy policy sitemap Login