CHROMOGENIC IN SITU HYBRIDIZATION (CISH) PROBES Login Register Search Company Diseases Biomarkers Confirmatory Resources Contact SEARCH OUR PRODUCT CATALOG Search As of December 4th, Empire is operating as an essential New York State business and has no production or shipping delays FISH PROBE PRODUCTS & SERVICES Popular Panels Copy Number Variation Break Apart Fusions Dual Color Control Probes Custom Design CISH Probes Mouse Probes Search by Region REQUEST MORE INFORMATION Send Message CISH Probes Probe design for CISH is very similar to that for FISH with differences only in labelling and detection. FISH probes are generally labelled with a variety of different fluorescent tags and can only be detected under a fluorescence microscope, whereas CISH probes are labelled with biotin or digoxigenin and can be detected using a bright-field microscope. CISH methodology may be used to evaluate gene amplification, gene deletion, chromosome translocation, and chromosome number. CISH utilizes conventional peroxidase or alkaline phosphatase reactions visualized under a standard bright-field microscope, and is applicable to formalin-fixed, paraffin-embedded (FFPE) tissues, blood or bone marrow smears, metaphase chromosome spreads, and fixed cells. How Does CISH Compare To FISH & IHC? CISH FISH IHC Microscope Bright-field Fluorescence Bright-field Signal stability Archivable Fades over time Archivable Magnification 40x 60–100x 20–40x Morphology Good Limited Good Amount of training required Medium High Low Internal control Yes Yes No Interpretation Objective/quantitative Objective/quantitative Subjective/qualitative Amplification CISH Probes Empire Genomics currently offers over 30,000 CISH probes that are used to detect the amplification of specific genes. Search for almost any human gene and chances are we can make a probe that covers it in as little as 10 days. Search A1BG CISH Probe CHR19:58,858,171-58,864,865 Add To Cart A1CF CISH Probe CHR10:52,559,168-52,645,435 Add To Cart A2M CISH Probe CHR12:9,220,303-9,268,558 Add To Cart A2ML1 CISH Probe CHR12:8,975,149-9,029,377 Add To Cart A3GALT2 CISH Probe CHR1:33,306,765-33,321,097 Add To Cart A4GALT CISH Probe CHR22:43,088,126-43,116,876 Add To Cart A4GNT CISH Probe CHR3:137,842,559-137,851,229 Add To Cart AAA1 CISH Probe CHR7:34,386,123-34,797,884 Add To Cart AAAS CISH Probe CHR12:53,701,239-53,715,412 Add To Cart AACS CISH Probe CHR12:125,549,924-125,627,871 Add To Cart AADAC CISH Probe CHR3:151,531,860-151,546,276 Add To Cart AADACL2 CISH Probe CHR3:151,451,703-151,475,556 Add To Cart AADACL3 CISH Probe CHR1:12,776,117-12,788,726 Add To Cart AADACL4 CISH Probe CHR1:12,704,565-12,727,097 Add To Cart AADAT CISH Probe CHR4:170,981,372-171,011,372 Add To Cart AAED1 CISH Probe CHR9:96,641,250-96,655,330 Add To Cart AAGAB CISH Probe CHR15:67,493,366-67,547,074 Add To Cart AAK1 CISH Probe CHR2:69,685,126-69,870,977 Add To Cart AAMDC CISH Probe CHR11:77,821,113-77,901,280 Add To Cart AAMP CISH Probe CHR2:219,128,851-219,134,893 Add To Cart Previous 1 2 3 4 5 … 1959 Next Empire Genomics, Inc. Our mission is to improve individual patient care through the integration of innovative molecular diagnostic technologies. Contact Info 1000 Youngs Road, Suite 207 Williamsville, New York 14221 Tel. (716) 856-3873 | (800) 715-5880 info@empiregenomics.com Copyright © 2021 Empire Genomics, Inc.. Privacy Policy