News & Insights Contact Us Databases English Services About Us Our Science THERAPEUTIC AREAS Therapeutic Areas At Crown Bioscience, we are driven by our mission to ensure that every patient gets the right treatment at the right time. That is why we are trusted by the world’s leading biopharmaceutical companies to advance their preclinical and translational research programs. With our extensive experience in the areas of oncology, immuno-oncology, and immune-mediated inflammatory diseases. Leverage the infinite possibilities of scientific innovation. Oncology Accelerate your oncology program using our comprehensive suite of in vivo, in vitro and ex vivo biological services Learn More Immune-Mediated Inflammatory Diseases Advance IMID drug development with our integrated preclinical platform for diseases such as IBD, Rheumatoid Arthritis and Diabetes Learn More Immuno-oncology Explore a unique collection of validated syngeneic, mouse tumor homograft models, and humanized genetically engineered mouse models Learn More Cystopathic Diseases Discover a unique high content screening platform for Autosomal Dominant Polycystic Kidney Disease to enable the recapitulation of the in vivo disease phenotype Learn More © 2021 Crown BioScience. Terms of Use Privacy Statement

News & Insights Contact Us Databases English Services About Us Our Science THERAPEUTIC AREA IMMUNE MEDIATED INFLAMMATORY DISEASES Immune-Mediated Inflammatory Diseases (IMID) Rapidly select lead anti-inflammatory agents with our integrated preclinical platform A Translational Platform of In Vivo Inflammatory and Autoimmune Disease Models Our catalogue of inflammation models recapitulates key clinical and pathological features of human disease, forming an integrated platform for preclinical drug development. Model diverse autoimmune and inflammatory disease mechanisms in vivo. Determine agent efficacy and response to treatment. Rapidly select anti-inflammatory lead agents. In most cases, we can initiate preclinical studies on our inflammation platform in as little as fourteen days. Promising agents can be quickly identified in vivo and advanced with confidence in their clinical efficacy. Available Inflammation/Autoimmune Models Inflammatory Bowel Disease (IBD) In Vivo Models Systemic Lupus Erythematosus (SLE) In Vivo Models Liver Injury In Vivo Models Rheumatoid Arthritis (RA) In Vivo Models Type 1 Diabetes (T1D) In Vivo Models Hypersensitivity In Vivo Models Multiple Sclerosis (MS) In Vivo Models Peritonitis In Vivo Models Preclinical Inflammation and Autoimmune Platform Features Comprehensive selection of acute and chronic inflammation models. Diverse mechanisms of inflammatory and autoimmune disease. Innate and regulatory cell-mediated models. Robust determination of efficacy and response to treatment. Expert model selection and study design consultation. Discuss your IMID Project Tell us about your needs CONTACT US Oncology Immuno-oncology Immune-Mediated Inflammatory Diseases Cystopathic Diseases © 2021 Crown BioScience. Terms of Use Privacy Statement