Test Catalog Ordering Insurance & Billing Test Results Investigate Variants Register Sign In IntelliTest Manager Contact About Us Motor Neuron Diseases Hereditary motor neuron diseases affect the nerves that control voluntary muscle activity, which includes diseases such as amyotrophic lateral sclerosis (ALS), hereditary spastic paraplegia (HSP), and spinal muscular atrophy (SMA). These conditions are variably progressive with symptoms that include muscle weakness and atrophy, spasticity, and overactive tendon reflexes. Physician Resources Patient Resources Test Catalog Video: HSP and Ataxia Next Generation Sequencing Testing for Genetic Causes of Motor Neuron Disease Athena Diagnostics offers hereditary spastic paraplegia (HSP) evaluations to aid in diagnosis. HSP affects between 1.3 and 9.6 in 100,000 and is frequently diagnosed by exclusion, since MRI, cerebrospinal fluid (CSF) studies, electromyogram (EMG) and nerve conduction velocity (NCV) are often uninformative. (GeneReviews) We also offer genetic testing for amyotrophic lateral sclerosis (ALS) that may detect up to 70% of familial disease. Over 5,600 individuals in the U.S. are diagnosed with ALS each year, and 30,000 are estimated to have the disease at any one time. (ALSA.org). Nearly 1/3 of ALS patients are misdiagnosed with vascular pseudobulbar palsy or cervical myelopathy, with 20% undergoing unnecessary surgeries as a result. (Srinivasan J et al.) Our staff of genetic counselors and laboratory directors is available to assist you in the ordering process. Guides Motor Neuron Disease Guide HSP Algorithm Athena Insight Guide Further Educational Resources Quest Diagnostics Medical Education Center Quest Diagnostics Expert Newsletters Letters of Medical Necessity HSP, Comprehensive Evaluation - Test Code 6630 HSP, Common Sporadic Evaluation - Test Code 6601 HSP, Complete Dominant Evaluation - Test Code 6610 HSP, Common Dominant Evaluation - Test Code 6611 Medical Affairs Resources Athena Diagnostics Client Services - (800) 394-4493 Option 2 Athena Diagnostics Genetic Counselors - Genetics@AthenaDiagnostics.com Please select option from dropdown: Patient Physician Insurance Client Family Member The Person I spoke with was knowledgeable: I know what I need to do to complete the AAP application process: Yes No Please rate your call: My experience was exceptional My experience was average My experience was below average My experience will prevent me from ordering testing Do you have suggestions for making the APP education process more sucessful?: Did you find this page helpful? Yes No E-mail: If you'd like any follow up communication from this survey please provide your contact information here. Thank you for providing valueable feedback! Athena Diagnostics is a leader in diagnostic testing for neurological diseases and offers innovative tests for Alzheimer's disease, muscular dystrophy and other neuromuscular and developmental disorders. View Full Catalog About Us Accreditations and Licensing Patents Held Careers Copyright © 2021 Athena Diagnostics, Inc. All trademarks and service marks identified by ®, ™ or ℠ symbols or appearing in type form different from that of the surrounding text are marks owned by or licensed to Athena Diagnostics, Inc., its subsidiaries or affiliates, unless otherwise identified as being owned by another entity. See Full Notice Genetic Testing Policies Cookies Notice Privacy Shield Privacy Terms DO NOT SELL MY PERSONAL INFORMATION Language Assistance / Non-Discrimination Notice Asistencia de Idiomas / Aviso de no Discriminación 語言協助 / 不歧視通知 200 Forest Street, 2nd Floor Marlborough, MA 01752 Phone (508) 756-2886 Need Help?