NuVasive POROUS PEEK™ TECHNOLOGY Manufactured through a proprietary extrusion process, the first-of-its-kind porous architecture is designed to promote bone in-growth1 while maintaining the biomechanical1 and imaging properties of PEEK. Porous PEEK Advanced Materials Science® Adhering to the three core principles of Advanced Materials Science—Surface, Structure, and Imaging—NuVasive has pioneered design and manufacturing methods that combine the inherent benefits of porosity with the advantageous material properties of PEEK to create implants intelligently designed for fusion. PATIENTS Significantly better outcomes than structural allograft or smooth PEEK implants as early as 6 weeks as demonstrated in animal models.2 SURGEONS Porous PEEK implants have demonstrated >3x the integration strength of smooth, solid PEEK implants as demonstrated in animal models.3 HOSPITALS Porous PEEK avoids the need for in-hospital sterilization through sterile packaged implants. Porosity drives integration strength Interconnected porous PEEK scaffold supports strong mechanical interlock through bone in-growth in preclinical animal models. 1-2 Porosity drives outcomes Significant improvements in clinical outcomes reported with porous PEEK vs. smooth PEEK and structural allograft in anterior cervical discectomy and fusion as early as 6 weeks.3 Durable porous structure Porous PEEK maintains high porosity under conditions that replicate anatomic loading and resists abrasion damage and delamination under impacted insertion.4,5 Clear imaging for postoperative confirmation of fusion Created with imaging in mind, Porous PEEK leverages the radiolucent properties of PEEK to enable radiographic visualization on a variety of imaging modalities. This provides surgeons with the ability to assess placement of the implant intraoperatively and confirm fusion postoperatively. Porous PEEK portfolio COHERE TLIF-A COHERE TLIF-O COHERE XLIF COHERE CERVICAL COALESCE TLIF/PLIF COALESCE TLIF For important product safety information on each of the implants in the Porous PEEK portfolio, including, but not limited to, indications for use, contraindications, warnings, precautions, and potential adverse effects, please see the product specific Instructions for Use which can be found at nuvasive.com/eifu. 1. Evans NT, Torstrick FB, Lee CS, et al. High-strength, surface-porous polyether-ether-ketone for load-bearing orthopedic implants. Acta Biomater 2015;13:159-67. 2. Hill CP and Strenge KB. Early clinical outcomes comparing porous PEEK, smooth PEEK, and structural allograft interbody devices for anterior cervical discectomy and fusion. J Spine Neurosurg 2019;8(1):1-7i. 3. Torstrick FB, Lin ASP, Potter D, et al. Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK. Biomaterials 2018;185:106-16. 4. Cheng A, Cohen DJ, Boyan BD, et al. Laser-sintered constructs with bio-inspired porosity and surface micro/nano-roughness enhance mesenchymal stem cell differentiation and matrix mineralization in vitro. Calcif Tissue Int 2016;99:625-37. 5. Evans NT, Torstrick FB, Lee CS, et al. High strength surface-porous polyether-ether-ketone for load bearing applications. Acta Biomater 2015;13:159-67. SOLUTIONS PROCEDURES CONDITIONS RESOURCES ABOUT INVESTOR RELATIONS CAREERS CONTACT 7475 Lusk Blvd. San Diego, CA 92121 USA Toll Free 800-455-1476 Main 858-909-1800 FAX 800-475-9134 info@nuvasive.com facebook instagram twitter linkedin youtube The materials on this website are for your general educational information only. Information you read on this website cannot replace the relationship that you have with your healthcare professional. We do not practice medicine or provide medical services or advice as a part of this website. You should always talk to your healthcare professional for diagnosis and treatment. Cookie Settings Terms & Conditions Privacy ©2021 NuVasive®, Inc. We use cookies to deliver the best browsing experience, personalize content, service targeted advertisements and analyze site traffic. You can find out more or disable specific cookies by clicking “Cookie Settings.” You can withdraw your consent at any time using the Cookie Settings link in the footer of our website. Cookie Settings Accept Only Necessary Cookies Accept All Cookies