Test Catalog Ordering Insurance & Billing Test Results Investigate Variants Register Sign In IntelliTest Manager Contact About Us Epilepsy Epilepsy is a group of disorders caused by disturbances with electrical signaling in the brain. According to Epilepsy.com, epilepsy is the most common severe neurological condition, affecting 65 million individuals worldwide and 2 million in the US at any one time. Approximately 150,000 individuals in the US are diagnosed every year, and one-third of patients have poorly-controlled seizures despite trials of several antiepileptic drugs. Physician Resources Patient Resources Test Catalog Testing for Genetic and Immunologic Causes of Epilepsy Athena Diagnostics' Epilepsy Advanced Sequencing Evaluations are organized by phenotype in order to make test selection easy and efficient. Panels were created based on International League Against Epilepsy (ILAE) classification and may detect a disease-causing mutation in 48% of patients (Lemke et al.). Genes were chosen based on monogenic disorders for which epilepsy is a key feature according to the Online Mendelian Inheritance in Man (OMIM) database. Athena Diagnostics also offers testing for autoimmune causes of epilepsy. Autoantibodies to neuronal proteins have been found in the serum and CSF of over 10% of patients with epilepsy, whether newly-diagnosed or established (Brenner et al.). Patients with these pathogenic autoantibodies may respond well to a combination of antiepileptic drugs and immunotherapy. Our staff of genetic counselors and laboratory directors is available to assist you in the ordering process. Guides Epilepsy Next-Generation Sequencing Guide Autoimmune Epilepsy Guide Athena Insight Guide Letters of Medical Necessity Epilepsy Advanced Sequencing and CNV Evaluation Sub panels Generalized, Absence, Focal, Febrile, and Myoclonic Epilepsies Epileptic Encephalopathy Developmental Brain Malformations Intellectual Disability Neuronal Ceroid Lipofuscinosis Epilepsy with Migraine Syndromic Disorders Infantile Spasms Complete SCN1A Evaluation Order the EpilepsyTest Catalog Medical Affairs Resources Athena Diagnostics Client Services - (800) 394-4493 Option 2 Athena Diagnostics Genetic Counselors - Genetics@AthenaDiagnostics.com Please select option from dropdown: Patient Physician Insurance Client Family Member The Person I spoke with was knowledgeable: I know what I need to do to complete the AAP application process: Yes No Please rate your call: My experience was exceptional My experience was average My experience was below average My experience will prevent me from ordering testing Do you have suggestions for making the APP education process more sucessful?: Did you find this page helpful? Yes No E-mail: If you'd like any follow up communication from this survey please provide your contact information here. Thank you for providing valueable feedback! Athena Diagnostics is a leader in diagnostic testing for neurological diseases and offers innovative tests for Alzheimer's disease, muscular dystrophy and other neuromuscular and developmental disorders. View Full Catalog About Us Accreditations and Licensing Patents Held Careers Copyright © 2021 Athena Diagnostics, Inc. All trademarks and service marks identified by ®, ™ or ℠ symbols or appearing in type form different from that of the surrounding text are marks owned by or licensed to Athena Diagnostics, Inc., its subsidiaries or affiliates, unless otherwise identified as being owned by another entity. See Full Notice Genetic Testing Policies Cookies Notice Privacy Shield Privacy Terms DO NOT SELL MY PERSONAL INFORMATION Language Assistance / Non-Discrimination Notice Asistencia de Idiomas / Aviso de no Discriminación 語言協助 / 不歧視通知 200 Forest Street, 2nd Floor Marlborough, MA 01752 Phone (508) 756-2886 Need Help?