NEWS News NOV 16 2021 Roivant Discovery and Edelris Enter into Drug Discovery Research Collaboration Roivant Discovery, the drug discovery engine of Roivant Sciences, and Edelris are pleased to announce that they have entered into a Research Collaboration to identify small molecule ligands against a target of interest for Roivant. Learn more OCT 19 2021 We are looking for a talented and experienced Research Scientist in Biochemistry (F/H) Our expanding Team is looking for an experienced Research Scientist in Biochemistry (F/H) Learn more OCT 19 2021 Opportunity for a Laboratory Technician in Biochemistry (F/H) Due to sustained growth in our Screening department, we have a job opportunity for a talented Laboratory Technician in Biochemistry (F/H) Learn more OCT 12 2021 Opportunity for a Research Scientist in Medicinal Chemistry (F/H) Our expanding team is looking for a Research Scientist in Medicinal Chemistry (F/H) Learn more OCT 12 2021 Looking for a Laboratory Technician in Organic Chemistry and Synthesis (F/H) We are experiencing a sustained growth of our business, our expanding Medicinal Chemistry and synthesis teams are hiring a Laboratory Technician (Bac +2, Bac +3) Learn more JUL 18 2021 Opportunity for a Laboratory Technician in Biochemistry (F/H) Our expanding team is looking for a Laboratory Technician in Biochemistry. Learn more JUN 29 2021 Nadège Laborde appointed as Managing Director To support its ambition, EDELRIS is proud to welcome Nadège Laborde as its Managing Director. Learn more JUN 25 2021 Senior Research Scientist in Medicinal Chemistry (H/F) Due to a sustained growth of our business, we are opening new positions in our organization. Our expanding Edelris Medicinal Chemistry team is now hiring an experienced PhD in Medicinal Chemistry Learn more JUN 25 2021 Research Scientist in Medicinal Chemistry (H/F) Our business is growing and we are looking for a PhD in chemistry to join or expanding team of organic and medicinal chemistry experts. Learn more JUN 25 2021 Opportunity for a Laboratory Technician in organic chemistry and synthesis (H/F) We are experiencing a sustained growth of our business and our expanding Medicinal Chemistry and synthesis teams are hiring an experienced Laboratory Technician (Bac +2/ Bac +3). Learn more APR 23 2021 AS-MS symposium announcement Thrilling line-up of speakers for the “1st Edelris Symposium on Affinity Selection-Mass Spectrometry in Drug Discovery” - June 2 & 3 - If you need to accelerate the selection of high-quality hits for your biological targets, If you are having difficulties identifying small-molecule ligands through other screening paradigms, Register and listen to the Symposium’s leading speakers, They will share their experiences so you can take full profit from this breakthrough screening technology. Learn more FEB 26 2021 Edelris expands into the growing research area of PROTACS EDELRIS has signed an important research agreement on the AS-MS screening of several E3-ligases, a cardinal component in the PROTAC technology. Our unique 2 Million diverse, 3D-rich, and tangible Keymical Space™ will serve as the compound screening pool. Learn more FEB 18 2020 Edelris and Galapagos announce extension of a multi‐year research agreement Building upon the positive results of an ongoing research collaboration aimed at the production of jointly designed chemical libraries, Edelris and Galapagos announce today that they have agreed to extend their multi‐year partnership . Learn more FEB 04 2020 The Max Planck Institute and Edelris Announce a Research Collaboration Under the terms of the agreement, the aim of the collaboration will be to identify novel ligands towards groundbreaking biological targets. Learn more MAY 02 2019 Edelris in ESCulab - the story continues… Edelris will continue as a partner in ESCulab: the new project under the European Lead Factory brand. Learn more FEB 12 2019 We are moving to a new location in BioParc Lyon. We are happy to announce a new step forward with our move into the state-of-the-art laboratories in BioParc Learn more MAY 30 2018 Edelris is looking for a talented Research Associate (Analytical Chemistry) We are a leading Drug Discovery CRO for Life Sciences organizations, providing expert Organic, High-Throughput, Medicinal and Analytical Chemistry services to the Pharmaceutical, Cosmetic, Crop Protection and Biotech markets. Learn more MAY 23 2018 Edelris is looking for talented Research Associates B.Sc./M.Sc. (Organic/Medicinal Chemistry) We are a leading Drug Discovery CRO for Life Sciences organizations, providing expert Organic, High-Throughput, Medicinal and Analytical Chemistry services to the Pharmaceutical, Cosmetic, Crop Protection and Biotech markets. Due to a sustained growth of our business, we are opening new positions in our organization. We are looking for talented Research Associates (M/F) to join our organization based in Lyon, France. Learn more NOV 06 2017 Delivering 40 000 compounds to European Lead Factory : Learnings & Achievement Meeting 2017 We showcased the strategy put in place within Edelris to meet the target of delivering 40K innovative compounds to the ELF Public Compound Collection. By using the Lean Six Sigma approach we were able to significantly adjust our production tool, enabling us to reallocate effort to solving other demanding problems such as scaffold validation and additional value adding tasks. Key Performance Indicators have been shared and discussed. Learn more SEP 19 2017 EFMC ASMC 2017 – Results from our collaboration with Merck EDELRIS had the opportunity in August 2017 to present the work carried out in collaboration with Merck. This collaboration is a perfect example of the relevance and complementarity of EDELRIS’ Services. Learn more JUL 21 2017 Edelris is looking for talented organic/medicinal chemists We are a leading Drug Discovery CRO for Life Sciences Organizations, providing expert Organic High-Throughput, Medicinal Chemistry services... Learn more JUL 03 2017 RICT in Toulouse Edelris will give a presentation on "Mining from NP-Like Fragments in 3D: Discovery of a Potent Caspase-1 Inhibitor" Learn more JUN 12 2017 WPC Mastering Medicinal Chemistry (Boston, June 15th) Edelris will present positive results obtained with 3D fragments on Cyclophilin-D Learn more APR 10 2017 The Annual Meeting 2017 American Association for Cancer Research Our partner Bayer HealthCare presented interesting results from a collaboration with EDELRIS at the Annual Meeting AARC in Washington. This study case concerns a service of hit to lead on an epigenetic regulator: ATAD2. The work carried out by EDELRIS EDELRIS improved the affinity, selectivity and diffusion in tissues from Hits initially identified from a DNA-encoded compound libraries. Learn more MAR 17 2017 ACS 2017 (San Francisco) EMD-Serono will reveal new results on Cyclophilin-D inhibitors originating from Edelris 3D-fragments Learn more JAN 31 2017 Research Collaboration Agreement signed with Pfizer Inc. Edelris s.a.s., a leading medicinal chemistry company focused on applying its EDEN (Edelris Discovery ENgine) technology [...] Learn more JAN 12 2017 Edelris is looking for talented organic/medicinal chemists Designing and perfoming innovative molecule syntheses with a strong therapeutic potential Learn more SEP 09 2016 FBLD Boston 2016 Edelris will present positive results obtained with 3D fragments on Cyclophilin-D Learn more SEP 08 2016 FBLD Boston 2016 Mining from NP-Like Fragments in 3D: discovery of a Potent Caspase-1 Inhibitor presented by Edelris Learn more AUG 24 2016 SAHOC2016: [5+2]-Cycloaddition reactions for the generation of diverse 3D-scaffolds and library synthesis Cycloaddition reactions are highly useful tools to address 3D-rich and functionalized scaffolds. This presentation will show the successful applications of [5+2]-cycloaddition reactions to access library scaffolds containing seven-membered rings. The chemistries were validated by the University of Leeds scientists and after transfer of knowledge to our scientists at EDELRIS, up-scaling and final library syntheses were effectively performed. Hurdles, solutions and outcomes will be discussed. Learn more AUG 23 2016 Unprecedented inhibitors of the ATAD2 bromodomain from a DNA-encoded chemical library screen On the occasion of the 5th International Symposium on DNA-encoded chemical libraries (Zürich, August 26, 2016), Bayer AG discloses a poster co-authored by X-Chem and Edelris, and describing the discovery of BAY-850, a selective ATAD2 small molecule inhibitor, underscoring the value of DNA-encoded chemical libraries to address difficult-to-drug targets (soon to be published). Learn more JUL 12 2016 [3+2]-Cycloaddition reaction: Synthesis of Libraries of Drug-Like pyrrolidine scaffolds The [3+2]-cycloaddition reaction is a powerful tool to address 3D-rich and highly functionalized scaffolds for chemical library development. Applying this methodology, two diverse pyrrolidine containing scaffolds were designed. The in situ generated nitrone was reacted with N-Boc 2,5-dihydro-1H-pyrrole and its analog. The obtained isoxazolidine cycloaddition adducts were reduced and functionalized, leading to multiple entry points for diversity generation. Two 500-compound libraries were synthesized, validating the concept. Learn more JUN 28 2016 Scaffold Hopping from Complex 3D Fragments There is a strong interest for the discovery of novel inhibitors of Caspase-1 (ICE), a protein involved in various inflammatory diseases such as rheumatoid arthritis, osteoarthritis or psoriasis. In order to develop new inhibitors, we used our EDEN platform (Edelris Discovery ENgine) to successfully explore the possibility to rescaffold competitor's ligands from innovative, 3D-enriched Keymical FragmentsTM. Learn more Legal notice Credits Phone: +33 (0)437 561 900 60, Avenue Rockefeller, Bioparc, Bioserra 1 Building, 69008 LYON, FRANCE