About Our People Resources Careers News & Events Contact Drug Development Crop Protection Chemical Safety Crop Protection|Investigative|Preliminary toxicology Preliminary Toxicology Here at Sequani, we are proud of the support we give to clients and the excellent way we manage early stage toxicology studies in rodent and non-rodent species. At the early stages of product development rapid turnaround and communication of results are crucial. The Sequani team is second to none in providing this service with attention to detail and close collaboration with our Sponsors. We have extensive experience in this area including working with challenging molecules. INTRODUCTION A highly experienced team of study directors works closely with clients to ensure our work meets the needs of both product development and international regulatory standards. We can conduct studies by all routes of exposure other than inhalation and we have extensive experience in undertaking studies by the dietary route. In addition to the standard toxicology services, we are able to offer special expertise in the following areas: Creative and responsive services for early stage investigative toxicology. Non-rodent (dog and minipig) toxicology. Toxicology studies in mice. Toxicokinetic support. Meeting challenging time-lines. Highly experienced in-house toxicological pathologists. Our study directors are highly responsive and are actively involved with their projects from inception through to report finalisation. They work closely with the on-site laboratory animal services, formulation sciences, analytical chemistry, bioanalysis, clinical pathology, biomarkers, pathology, QA and information technology staff to ensure that clients receive high quality studies and reports, whatever the type. We have a reputation for meeting, or beating, reporting dates even against the most difficult target times. We always provide good practical scientific input into the study design and reporting but also have the ability to contribute a more specialised scientific content where required. STUDY TYPES • Comparative and early development toxicity Rodent and non-rodent Standard screening designs available Bespoke studies Toxicokinetics MTD and dose range-finding Repeat Dose Toxicity Investigative studies Bespoke study designs to investigate specific toxicological issues DOSING ROUTES Oral gavage Oral dietary Oral capsule Dermal SPECIES Rat Mouse Rabbit Dog Minipig CONTACT US LET'S FOCUS OUR NEWS & EVENTS European Teratology Society (ETS) 11 September 2014 Richard Bartlett appointed Secretary of the European Teratology Society READ MORE Celebrating a commitment to training 12 August 2014 Sequani's training is recognised for its quality and scope READ MORE Meet the Sequani team across Europe via our Autumn conference schedule 31 July 2014 Our experts will be at major meetings and conferences throughout the Autumn. Do come and see us to hear about our latest work and discuss forthcoming ... READ MORE VIEW ALL ARTICLES RELATED SPECIALISMS Investigative PRELIMINARY TOXICOLOGY Studies led by our highly experienced team of study directors to meet your product development and international regulatory needs Investigative GENETIC TOXICOLOGY A comprehensive range of genetic toxicity services for preclinical assessment and the early screening of candidate compounds Investigative BIOANALYSIS Bespoke analysis using advanced liquid chromatography and Sciex tandem mass spectrometry Investigative FORMULATION DEVELOPMENT Tailored service to optimise vehicle section and formulation methodology ‹ › VIEW ALL great people, great work, real results HOW CAN WE HELP? Tel.: +44 1531 634121 Fax: +44 1531 634753 Sequani Limited, Bromyard Road, Ledbury HR8 1LH United Kingdom CONTACT US Terms of Use | Privacy