RecipharmNewsEventsCareersInsights Home > Products > Inhalation Devices > BK357 MDI Valve and Actuator BK357 Metered Dose Inhaler (MDI) Valve and Actuator The BK357 MDI Valve As the most technically complex element in a metered dose inhaler (MDI), the valve is critical to delivering a consistent and precise metered dose of medication to patients. Our MDI valves are firmly established as one of the major HFA valves worldwide, forming a critical component in several FDA approved products. They have been developed to work with a wide range of formulations with low levels of extractables and leachables to ensure that they are both versatile and clean. Manufacturing Constructed from regulatory approved plastic, metal and elastomeric materials Specifically developed proprietary elastomer formulation Cleanroom manufacture Supported by in-house elastomer and ethanol extraction manufacturing facilities Robust cGMP compliant commercial supply chain Device Capillary retention design Exceptionally low levels of extractables and leachables Consistent through life performance Low drug deposition onto material surfaces Low drug absorption into components Low moisture ingress Materials inert to interaction with formulation Loss of prime characteristics to support dosing regime Anodised ferrules for cleanliness High speed pressure filling by design Ability to cold fill Designed to fit 20mm neck containers Customisation Suitable for ethanol and non-ethanol formulations Inverted or upright use with diptube Standard dose size ranges from 25-100µl Design fine tuneable to meet specific customer requirements: Leakage Shot weight Emitted dose Compatibility with active Usable with HFA propellant 134a and 227 Compatible with cut edge & roll neck aluminium or stainless steel canisters Complimentary press & breathe or dose counting actuators available to optimise valve performance Support Valve performance supports inhaler shelf life up to 3 years Dedicated in-house laboratory to support product testing DMF documentation available Actuator Our actuators are optimised to work with our MDI valves and common canisters. They are 100% airflow tested and supplied ready for immediate use in final packaging operations. Should you need exclusive actuator designs or formula-specific devices, we develop customised actuators in parallel with the chosen container closure system. Key Features Available in 2 body lengths to accommodate 14ml and 19ml canisters Supplied with dust cap to keep mouthpiece clean Range of exit orifice diameters and lengths available to suit end application Orifice diameters range from 0.22mm to 0.58mm Fully customisable sump geometry available 100% airflow tested to specification Available in standard range of colours or customisable to Pantone reference Actuator and dust cap can be provided with embossed detail or plain Polypropylene construction with 21 CFR material compliance Robust cGMP compliant commercial supply chain Contact an Expert View our fact sheet More in Inhalation Page BK640 Dose Counting Actuator Read More Page Easifill MDI Valve Read More Page Device Contract Manufacturing Read More Looking for another product? Products Bespak Europe Ltd Registered office: Bergen Way North Lynn Industrial Estate, King’s Lynn Norfolk PE30 2JJ. United Kingdom Quick Links Products Services Insights About us About Recipharm Contact Us Email Linkedin Privacy NoticeLegal StatementCookie PolicyTerms & ConditionsModern Slavery Act StatementStatement of Investment PrinciplesSitemap Website by Farrows By continuing to browse the site you are agreeing to our use of cookies I Understand