HOME BOOKSTORE USEFUL LINKS CONTACT US Sealed containers Could hydrogen peroxide decontamination affect the results of a sterility test? A case study of hydrogen peroxide penetration through the load packaging: a customer required support for «A Package Integrity Verification» which involved all the samples and consumables inside the Sterility Test Isolator. Author: Bernuzzi, Maria Luisa. Practical issues on PFS sterilization: an analysis of critical aspects Prefilled syringes offer several advantages over traditional packaging in vials. For example, microbial contamination is minimized due to less manipulation.This presentation discusses a method for sterilizing PFSs through a moist heat process, the most common and approved method used by pharmaceutical facilities for this type of products. The main issues to consider while sterilizing PFSs with a moist heat process are described. Author: Bernuzzi, Maria Luisa. Aqueous solutions in sealed containers: internal pressure under autoclaving This article is a technical support to the practice of autoclaving aqueous solutions in sealed containers. Two “classical” scientific contributions on the matter are due to Beck and to M. A. Joyce & J. W. Lorenz which are referred in the article. In this article, metric units (abs bar or abs mbar) are used for the pressure. KEYWORDS: moist-heat sterilization, steam sterilization of aqueous solutions, sealed containers, headspace volume, internal pressure, autoclaving, autoclave, superheated water sterilizers, steam/ air mixture sterilizers Author: Mascherpa, Vittorio. F0 value - What it means, how to calculate it and how to use it in moist-heat sterilization The purpose of this Fedegari Technical Note, firstly distributed in 1988 and perseveringly revised, is to clarify the nature of F0 and its related parameters (D, z, PNSU/SAL), and to explain their use and limits for the setting, adjustment, control and validation of moist-heat sterilization processes. Author: Mascherpa, Vittorio. Pistolesi, Dario. Process Aseptic processing Chemical bio-decontamination Cleaning Moist-heat sterilization Sterilization Application General(23) Environmental Monitoring(1) Hyaluronic Acid (Sodium Hyaluronate)(1) Package Integrity(1) Blood bags(2) Food(4) Pharma - Liquids(10) Pharmaceutical compounding(2) Pre-filled syringes (PFSs)(4) Robotics(2) Sealed containers(4) Validation(8) Other applications(8) Search Enter your keyword Process Select a process Aseptic processing Chemical bio-decontamination Cleaning Dry-heat sterilization Moist-heat sterilization Standards & regulations Sterilization Application Select an application Blood bags Environmental Monitoring Food General Hyaluronic Acid (Sodium Hyaluronate) Other applications Package Integrity Pharma - Liquids Pharmaceutical compounding Pre-filled syringes (PFSs) Robotics Sealed containers Validation Author: Select an author Mascherpa Vittorio Agalloco James Korczynski Michael S. Moldenhauer Jeanne Akers James Ferretti Sara Bernuzzi Maria Luisa Pistolesi Dario Mauri Sergio Sandle Tim Thorogood Doug Gori Andrea Member area If you are a registered user enter your e-mail address and password to log in. E-mail Password register! forgot your password ? About us What do you find here? Useful and detailed technical information regarding sterilization, bio-decontamination and cleaning processes. We aim to share our passion and knowledge providing valuable information for a better understanding of technologies, processes and equipment currently available in the market. This way, we hope to enhance good manufacturing practices and shape innovation. Who can benefit from our content? We offer a rich source to support students, researchers and professionals with high-quality papers and presentations. Who are we? Our collaborators are recognized and passionate professionals bringing together many years of experience on the above mentioned fields. How does it work? You can browse the articles by searching a term, category, subject or author. All the blog content is available for free, you just need to register to have full access to it. Contact us info@sterilize.it If you have any suggestion, comment or question, please contact us. If you would like to collaborate with technical documents, please contact us. Any material is subject to approval by our Scientific Committee. Follow us Newsletter Name Surname E-mail I accept the processing of my personal data in accordance with article 13 Legislative Decree 196/2003. © Copyright 2015 Sterilize.it. All rights reserved.