Contact English Home Company What we offer Partners Technical area and quality Sustainability Press release 1954 – 2013: ANTIBIOTICOS DE LEON, S.L.U. 1947 Letter from Sir Alexander Fleming to the pioneers of Antibiotics. 1954 Foundation of Antibióticos, S.A.as a pioneer in the manufacture of active pharmaceutical ingredients (APIs) with the largest fermentation (beta-lactam antibiotics) capacity in Europe. 1969 Starts manufacture of Ampicillin, Amoxicillin and other Sterile beta-lactams. 1972 First FDA inspection (USA). Antibióticos becomes a global leader. 1990 China enters into the production of penicillanic derivatives at a lower operating cost. Declining of leadership global position starts. 1992 Installation of the new Water Treatment plant. 2013 The advance of Asian countries in the sector brings Antibióticos bankrupt. 2014 – 2020: ADL BIOPHARMA 2014 The investment fund Black Toro Capital (BTC) acquires the assets in a bankruptcy process and Antibióticos de León, S.L.U, with trade name ADL BioPharma is established. Production activity is reactivated. 2015 The facilities are inspected and approved by the AEMPS. 2016 ADL obtains FMA from PMDA (Japan) and GMP approval from KFDA (Korea). 2017 The plant is audited and tested by the FDA (USA). The main fermentation facilities are revamped and updated with 8 fermenters of 225 m3. 2017 A new business strategy is defined, based on the use of fermentation capacity for use as CMO of non-Pharma grade molecules and the breaking of verticality in Pharma production, keeping only chemical production, mainly sterile. 2018 Reverse acquisition of Bionaturis by ADL BioPharma, creating the holding company ADL Bionatur, listed on BME Growth. Production focused in Biotech Markets. 2020 COVID-19 crisis takes a big toll on ADL and Kartesia, a new shareowner, takes control of the company introducing significant changes in both the Board of Directors and its management team. 2021- YTD: RELAUNCH OF ADL BIOPHARMA PROJECT 2021 Kartesia executes the purchase option whereby it acquires 100% of the shares. Turn around of the business starts and new ADL BioPharma is launched. Certifies Organizations Avenida Antibióticos, 59-61 24009 León, Spain Tel +34 987 895 800 Fax +34 987 895 803 © 2021 Antibióticos de León. All rights reserved Legal-notice | Privacy policy | Cookies policy

Contact English Home Company What we offer Partners Technical area and quality Sustainability Press release GET IN TOUCH ANYTIME! May you need any information regarding either our products or services, or what we can do for your project, do not hesitate to contact us.  EMAIL ADDRESS commercial@adlbiopharma.com purchasing@adlbiopharma.com job@adlbiopharma.com  CALL US Tel. +34 987 895 800 Fax +34 987 895 803  VISIT US Avenida Antibióticos, 59-61. 24009 León, Spain Certifies Organizations Avenida Antibióticos, 59-61 24009 León, Spain Tel +34 987 895 800 Fax +34 987 895 803 © 2021 Antibióticos de León. All rights reserved Legal-notice | Privacy policy | Cookies policy