CAPABILITIES CATALOG NEWS AND PUBLICATIONS ABOUT CONTACT US MODELS OF LOWER BACK PAIN AMD ARTHRITIS HOME » MODELS OF LOWER BACK PAIN AMD ARTHRITIS Models of Lower Back Pain amd Arthritis Post published: November 9, 2021 Post category: Pain / Publications Porsolt continues to expand, and improve its catalog of models for pain, inflammation and arthritis. This includes a rat model for Lower Back Pain, involving degeneration of the lumbar facet joints induced by intra-articular injection of monosodium iodoacetate (MIA). Evolution of the pain sensation is evaluated by tactile stimulation at the points of injury, and reactions to mechanical flexion/extension of the hind paws. Additional models of rheumatoid arthritis (RA) include: #arthritis rat model – chronic inflammatory pain caused by CFA in the ankle #polyarthritis rat model – chronic inflammatory pain caused by CFA in the base of the tail #osteoarthritis rat model – chronic inflammatory pain caused by MIA in the knee joint #osteoarthritis guinea pig model – chronic inflammatory pain associated with surgery of the knee Please contact us for further information and to learn more about our capabilities. contact@porsolt.com www.porsolt.com Read more articles Previous Post Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity Next Post Predictive Toxicology YOU MIGHT ALSO LIKE Preclinical profiling and safety studies of ABT-769 – A compound with potential for broad-spectrum antiepileptic activity September 11, 2005 Supplemental Studies for Cardiovascular Risk Assessment in Safety Pharmacology – A Critical Overview October 16, 2011 Whole-cell Configuration of the Patch-clamp Technique in the hERG Channel Assay. October 10, 2012 Categories Categories Select Category News Publications Cardiovascular system Central Nervous System Gastro-intestinal System Inflammation Obesity & Metabolic Disorders Oncology Pain Predictive Toxicity Respiratory System Safety Pharmacology Urogenital System Select Category Archives Archives Select Month November 2021 July 2021 June 2021 March 2021 November 2020 October 2020 November 2018 July 2018 May 2018 February 2018 January 2018 November 2017 August 2017 May 2017 May 2016 January 2016 October 2015 June 2014 March 2014 November 2013 October 2013 July 2013 March 2013 February 2013 October 2012 July 2012 March 2012 October 2011 August 2011 March 2011 August 2010 May 2010 January 2010 October 2009 June 2009 February 2009 October 2008 September 2008 April 2008 March 2008 February 2008 March 2007 October 2006 September 2005 November 2004 October 2004 July 2004 April 2004 October 2003 September 2003 December 2002 October 2002 December 2001 October 2001 December 2000 May 2000 March 2000 February 2000 Select Month Recent Posts Predictive Toxicology Models of Lower Back Pain amd Arthritis Employment Opportunities at Porsolt Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity Porsolt retains its AAALAC International accreditation News & Updates Sign up to get all the latest news and updates delivered directly to your email GO Accept GDPR Terms Search for: SEARCH BUTTON Follow Us © COPYRIGHT - PORSOLT 2021