Products Area of Interest Resources Support Company Careers Neuroscience Research Reimagine neuroscience with single cell and spatial multiomics Overview On-demand webinar Resources Publications Products Download brochure Journey deeper into the brain Gain a richer understanding of the nervous system and accelerate the discovery of fundamental biology driving complicated, multifactorial neurodegenerative, psychiatric, and neurodevelopmental diseases. Explore 10x Genomics single cell and spatial tools for neuroscience in this short video. Download eBook to Learn More Neurodegenerative Disease Build a complete picture of the complex biology of neurodegenerative diseases in multiple dimensions. Advance your understanding of how pathological features affect the surrounding microenvironment and deepen your insights into the cellular contribution to disease pathogenesis and progression. Psychiatric Disorders Discover the molecular foundations of psychiatric disorders with single cell and spatial technologies. Characterize disease-associated cellular phenotypes and uncover novel pathological effects. Explore the regulatory landscape of neural cells and identify epigenetic regulators of discrete cell types and states. Developmental Neuroscience Achieve a more detailed view of neural development and differentiation than previously possible. Dissect molecular pathways controlling cellular differentiation, identify novel cell subtype markers, and reveal the dynamic gene expression patterns and regulatory landscapes governing cell differentiation. On-demand webinar TREM2-Associated Cellular Responses in Alzheimer’s Disease Watch this featured webinar to see how single cell sequencing can reveal novel functional phenotypes of neural cells in disease. Learn about the effects of the Trem2 AD risk variant on distinct cell types, and hear about previously undescribed roles of glia in AD pathogenesis. See all Neuroscience On-Demand Webinars Explore featured resources to enhance your neuroscience research Brochure Explore how you can gain a better understanding of the cellular and molecular mechanisms underlying both normal brain function and disease with single cell and spatial gene expression tools. Download Brochure Application Note Learn how you can characterize large and complex biological tissues, such as the brain, at single cell resolution with Chromium Single Cell Gene Expression. Download App Note Poster See how you can examine gene expression profiles across different brain regions and in the context of disease by combining histological and transcriptomic analyses with Visium Spatial Gene Expression. View Poster Publications Neuroscience revealed: from development to health and disease Gain a holistic understanding of complex biology with technologies from 10x Genomics. See how neuroscientists are using these innovations to gain a multidimensional view of the nervous system. View all Neuroscience Publications Single-cell transcriptomic analysis of Alzheimer’s disease Mathys H et al. Nature. 2019 Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis Maniatis S et al. Science. 2019 Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis Weng Q et al. Cell Stem Cell. 2019 Products for Neuroscience research Single Cell Gene Expression Profile cell types and states with 3' gene expression, surface protein expression, and CRISPR perturbations in the same cell. Identify and characterize unique brain-region and disease-associated neural cell types to better understand the contributions of cellular states and subtypes to normal brain function and disease pathogenesis. More info Spatial Gene Expression Spatially profile gene expression with morphological context in intact FFPE or fresh frozen tissue sections. Localize molecularly defined cell types in context of brain tissue structures, and simultaneously detect morphology, activity, or connectivity to uncover new insights into brain development and disease. More info Targeted Gene Expression Profile a defined set of transcripts from single cells or fresh frozen tissue sections to focus on the genes that matter most. Use the pre-designed Human Neuroscience Panel containing 1,186 target genes for analysis of neurodegenerative and neuroimmune pathways. More info Single Cell ATAC Reveal the epigenomic landscape and analyze chromatin accessibility cell by cell to decipher gene regulatory mechanisms. Profile the chromatin accessibility of tens of thousands of single nuclei to gain insight into the regulatory dynamics that underlie normal neural development, aging, and disease. More info Single Cell Multiome ATAC + Gene Expression Explore combined gene expression and chromatin accessibility data from the same cell to uncover gene regulatory programs. Deeply characterize immune cell states, uncover gene regulatory programs driving immune cell lineage and differentiation. Identify target genes and cell types of genetic variants associated with immune-mediated disease. More info Reimagine neuroscience with single cell and spatial solutions from 10x Genomics View Products Contact Us ABOUT Products Platform Company Careers Contact Employment Verification LEGAL NOTICES Privacy Policy Terms of Use Email Preferences Other Legal Notices HEADQUARTERS +1 925 401 7300 +1 800 709 1208 info@10xgenomics.com RESOURCES Publications Support Videos SOCIAL SIGN UP FOR PRODUCT AND EVENT UPDATES Subscribe © 2021 10x Genomics. All Rights Reserved. English中文日本語