Enabling Precision Medicine for Breast Cancer Patients Breadcrumb Home Newsroom Blog Enabling Precision Medicine for Breast Cancer Patients October 19, 2021 Approximately every 2 minutes, a woman in the U.S. is diagnosed with breast cancer1. This high prevalence has led to rigorous standards of practice, from diagnosis to treatment. For oncologists, these standards are often foundational to therapy plans, especially when breast is one of the many cancers they will see every day. A recent survey found that oncology clinics typically see more than 74 patients each week2. However, care is shifting away from a one-size-fits-all approach. Cancer care has seen a rapid evolution toward what has become known as precision medicine. Precision medicine is a model where the care plan is customized to each patient and the unique hallmarks driving their cancer. The practice of precision medicine utilizes improved diagnostics and therapeutics, which have advanced outcomes and saved lives. But the shift toward precision oncology can create clinical confusion due to the vast number of breast cancer-focused tests. It can become further complicated when healthcare providers are required to utilize multiple cancer labs to complete the diverse range of tests for early-stage to advanced-stage breast cancer patients. The inconsistency of incorporating molecular profiling into cancer treatment was illustrated in a survey3 that polled 292 community-based oncologists and found that only 8% of providers ordered molecular profiling for breast cancer. In addition, when the polled physicians3 were asked to match molecular alterations with appropriate targeted therapies, up to 69% of the responses were incorrect. Similar results were observed from the patient perspective. A separate study that surveyed 203 stage III/IV breast cancer patients found that 72% had not received a genomic test for their disease. Molecular testing is an area of which patients are largely unfamiliar. This has been particularly true for patients treated at community centers, who were significantly less aware of genomic profiling than patients treated at an academic center4. It’s precisely these realities that fuel the NeoGenomics mission. We are dedicated to partnering alongside each cancer care team to improve outcomes. We strive to meet challenges in the cancer community. Navigating diagnostic test ordering and empowering physicians with quick and actionable results is the NeoGenomics purpose in action. NeoGenomics offers the continuum of testing: diagnostic, prognostic, predictive and germline testing for early-stage to advanced stage. Our breast cancer portfolio takes a more in-depth look at what’s driving the cancer, such as PD-L1 expression, as well as BRCA 1/2 and PIK3CA mutations. The NeoTYPE® Breast Tumor Profile analyzes 60 biomarkers through a combination of next-generation sequencing (NGS), FISH, and IHC and includes a summary interpretation of all results to help guide treatment decisions. This comprehensive and multimodal approach to breast cancer profiling is accurate and actionable. In an internal review of 100 consecutive NeoTYPE® Breast Tumor Profile cases informative for NGS, 96 patients had results with therapeutic implications, including clinical trials. For example, PIK3CA is an actionable biomarker. It is the second most common mutation observed in all breast cancer patients5 and the most common mutation in HR+/HER2- breast cancers. At NeoGenomics, we believe that every patient should have access to quality health care. We are proud to offer a first-of-its-kind sponsored testing program that provides eligible patients with an FDA-approved PIK3CA Mutation CDx Test at no cost. It can determine eligibility for PIQRAY® in patients with advanced or metastatic breast cancer harboring HR+/HER2- tumors. For a cancer typically with limited treatment options, this test can pave the way for more options. This is just one of the many offerings from NeoGenomics. Compared to other labs, NeoGenomics provides a complete suite of tests that meet the clinical demands throughout the breast cancer journey; all stages, all hormone status, and for all clinical needs. We are often referred to as a one-stop-shop for any cancer type because having diagnostic, prognostic, and predictive tests under one roof. This allows physicians to save time and reduce complexities by consolidating their testing into one lab. NeoGenomics is One Lab. Vital Answers. Transforming Care for Cancer Patients. References: https://www.nationalbreastcancer.org/breast-cancer-facts https://www.statista.com/statistics/606599/oncology-clinic-average-pati…. Singh BP, et al. J Clin Oncol. 2019;37:(suppl; abstr 10510). Stroiney A, et al. San Antonio Breast Cancer Symposium; Dec 8-11, 2020. Zardavas D, et al. Breast Cancer Res. 2014;16(1):201-210. Throughout the American Registry of Pathology Expert Opinions series, the focus is singular—to provide practical and useful guides to assist fellow pathologists in the pursuit of a precise diagnosis and a targeted approach for patient management. These articles reflect the views of a group of expert practitioners in subspecialty practice. These articles reflect the views of a group of experienced practitioners in subspecialty practice, with the goal to provide practical and useful guides to a specific diagnosis or problem area CONTACT US TO GET STARTED! Work with us – your premier oncology partner – to optimize cancer care for patients LEARN MORE Main navigation Diagnostic Services Pharma Services Data Services Inivata Patients Test Menu CONTACT US 9490 NeoGenomics Way Fort Myers, FL 33912 T: 239.768.0600 F: 239.690.4237 Glassdoor Icon Linkedin Icon Twitter Icon YouTube Icon MORE FROM NEO InVisionFirst®-Lung Lung Cancer Awareness Biomarker Assist™ KRAS SGT PIK3CA Mutation CDx Thyroid Testing Program NTRK NEONEWS SIGN UP Receive weekly updates on NeoGenomics tests, research, events, and publications. First Name last Name Email One Lab. Vital Answers. Transforming Care for Cancer Patients. Footer Utility Client Services About Billing Contact Careers NeoLink Login Copyright © 2021 NeoGenomics Laboratories. All rights Reserved. Privacy. Terms. Licensing. Do not sell my personal information. 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