Schrödinger SCIENCE BEHIND THE SCIENCE Schrödinger has made scientific breakthroughs across drug discovery and materials science through significant long-term investments in research. Schrödinger scientists have authored hundreds of peer-reviewed scientific publications that are frequently among the most cited in the field. You can access our scientific publications here. To cite the usage of Schrödinger technology, please click here. We have prepared several application-specific articles that dive into further detail. Explore the science behind Schrödinger’s industry-leading platform. Scientific Area (-) Remove All filter All Small Molecule Drug Discovery Apply Small Molecule Drug Discovery filter Biologics Drug Discovery Apply Biologics Drug Discovery filter Materials Science Apply Materials Science filter Type (-) Remove All filter All Application Note Apply Application Note filter Case Study Apply Case Study filter How Machine Learning Enables Accurate Prediction of Precursor Volatility How Machine Learning Enables Accurate Prediction of Volatility read more about how machine learning enables accurate prediction of precursor volatility The New Solution to the Induced Fit Docking Problem: How IFD-MD Rapidly and Reliably Predicts Accurate Ligand Binding Scientists from Schrödinger’s Structure Prediction, Structure Refinement, and Drug Discovery Groups recently published... read more about the new solution to the induced fit docking problem: how ifd-md rapidly and reliably predicts accurate ligand binding An Expedited Gene-to-Drug Approach using Thermo Scientific Cryo-EM and the Schrödinger Platform Here, we present the approach taken by Thermo Fisher Scientific and Schrödinger research teams that deployed GeneArt... read more about an expedited gene-to-drug approach using thermo scientific cryo-em and the schrödinger platform STORIES FROM DRUG DISCOVERY: Modeling Strategies in the Pursuit of Development Candidate in Oncology Program 1 In this month’s Stories from Drug Discovery series, Dr. Sayan Mondal, a Research Leader in Schrödinger’s Drug Discovery... read more about stories from drug discovery: modeling strategies in the pursuit of development candidate in oncology program 1 STORIES FROM DRUG DISCOVERY: Dialing Out Off-target Liabilities with Protein Residue Mutation FEP+ in an Active Drug Discovery Project Free energy calculations are revolutionizing how early-stage drug-discovery campaigns are undertaken. In this short, 10... read more about stories from drug discovery: dialing out off-target liabilities with protein residue mutation fep+ in an active drug discovery project Battery and Energy Storage Materials Schrödinger’s Materials Science solutions provide a comprehensive list of atomic-scale modeling and simulation tools... read more about battery and energy storage materials Improving the Accuracy of Protein Thermostability Predictions We sat down with Dr. Jianxin Duan to discuss his paper, “ Improving the Accuracy of Protein Thermostability Predictions... read more about improving the accuracy of protein thermostability predictions Massive Theoretical Screening of Organic Semiconductor Materials Using Cloud Computing Panasonic scientists in collaboration with Schrödinger researchers published a paper in The Journal of Physical... read more about massive theoretical screening of organic semiconductor materials using cloud computing Designing Macrocycles with Schrödinger Tools Macrocycles are a structurally broad class, including small molecules with cyclized linkages as well as large cyclic... read more about designing macrocycles with schrödinger tools Introducing a New in silico Workflow for Efficient and Automated Macrocycle Design Together with Sanofi, Schrödinger recently published a manuscript in the Journal of Medicinal Chemistry, titled “... read more about introducing a new in silico workflow for efficient and automated macrocycle design 1 2 3 Next Platform Platform Overview Small Molecule Drug Discovery Biologics Drug Discovery Materials Science Academic Licensing All Products Pipeline Learn Training Support & Documentation Scientific Events Science Articles Publications Our Company Team Corporate Responsibility Extrapolations Blog Working Here Current Positions Life at Schrödinger Investor Relations Overview Press Releases Investor Conferences Stock Information Analyst Coverage Financial Information Corporate Governance Shareholder Resources Sign In Download Software Contact Support Contact Us Twitter Linked In Subscribe to our newsletter Copyright © 2021 Schrödinger, Inc. Citations Privacy Policies Terms of Use FCOI Policy EULA Anti-Slavery Statement