Berg_Logo Site navigation ABOUT US RESEARCH & DEVELOPMENT PARTNERS MEDIA CAREERS CONTACT Search Research & Development Healthcare Professionals Publications RESEARCH & DEVELOPMENT Research and Development Healthcare Professionals Our Pipeline Publications Patients and Caregivers PUBLICATIONS AUGUST 21, 2020 High levels of ubidecarenone (oxidized CoQ 10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells Scientific Reports; 2020 August 17;10(1):13899 Jiaxin Sun, Chirag B Patel, Taichang Jang, Milton Merchant, Chen Chen, Shiva Kazerounian, Anne R Diers, Michael A Kiebish, Vivek K Vishnudas, Stephane Gesta, Rangaprasad Sarangarajan, Niven R Narain, Seema Nagpal, Lawrence Recht Metabolic reprogramming in cancer cells, vs. non-cancer cells, elevates levels of... JULY 22, 2020 Divergence in the metabolome between natural aging and Alzheimer’s disease Scientific Reports; 2020 July 22;10(1):12171 Holly C Hunsberger, Bennett P Greenwood, Vladimir Tolstikov , Niven R Narain , Michael A Kiebish , Christine Ann Denny Alzheimer’s disease (AD) is a progressive and debilitating neurodegenerative disorder and one of the leading causes of death in... JULY 16, 2020 Bayesian model infers drug repurposing candidates for treatment of COVID-19 Submitted for peer review. This abstract has been posted online to share with the scientific community given the severity of the COVID pandemic Michael A. Kiebish, Punit Shah, Rangaprasad Sarangarajan, Vivek K. Vishnudas, Stephane Gesta, Poornima... JULY 6, 2020 Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity GeroScience; 2020 July 6; doi: 10.1007/s11357-020-00221-0 Justin Darcy, Yimin Fang, Samuel McFadden, Matthew D. Lynes, Luiz O. Leiria, Jonathan M. Dreyfuss, Valerie Bussburg, Vladimir Tolstikov, Bennett Greenwood, Niven R. Narain, Michael A. Kiebish, Andrzej Bartke, Yu-Hua... MAY 29, 2020 Current Status of Metabolomic Biomarker Discovery: Impact of Study Design and Demographic Characteristics Metabolites; 2020 May 29;10(6):E224 Vladimir Tolstikov, A James Moser, Rangaprasad Sarangarajan, Niven R Narain, Michael A Kiebish Widespread application of omic technologies is evolving our understanding of population health and holds promise in providing precise guidance for selection of therapeutic... MAY 29, 2020 Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles Aging Cell; 2020 May 28;e13135 James Matthew Hinkley, Heather H. Cornnell, Robert A. Standley, Emily Y. Chen, Niven R. Narain, Bennett P. Greenwood, Valerie Bussberg, Vladimir V. Tolstikov, Michael A. Kiebish, Fanchao Yi, Rick B. Vega,... JANUARY 1, 2020 Skeletal muscle energetics and mitochondrial function are impaired following 10 days of bed rest in older adults The Journals of Gerontology: Series A 2020 Jan;pii: glaa001. doi: 10.1093/gerona/glaa001 Standley RA, Distefano G, Trevino MB, Chen E, Narain NR, Greenwood B, Kondakci G, Tolstikov VV, Kiebish MA, Yu G, Qi F, Kelly DP, Vega RB, Coen PM, Goodpaster BH Older adults exposed to periods of inactivity during hospitalization, illness... NOVEMBER 4, 2019 A Data-Driven Approach to Predicting Septic Shock in the Intensive Care Unit Biomedical Informatics Insights. 2019 Nov 4;11, 1178222619885147 Christopher R Yee, Niven R Narain, Viatcheslav R Akmaev, Vijetha Vemulapalli Early diagnosis of sepsis and septic shock has been unambiguously linked to lower mortality and better patient outcomes.... OCTOBER 1, 2019 12-lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat Cell Metabolism. 2019 Oct;30(4):768-783.e7 Luiz Osório Leiria, Chih-Hao Wang, Matthew D. Lynes, Kunyan Yang, Farnaz Shamsi, Mari Sato, Satoru Sugimoto, Emily Y. Chen, Valerie Bussberg, Niven R. Narain, Brian E. Sansbury, Justin Darcy, Tian Lian Huang,... SEPTEMBER 5, 2019 BAIcis: A novel Bayesian network structural learning algorithm and its comprehensive performance evaluation against open-source software Journal of Computational Biology. 2019 Sep 5;doi: 10.1089/cmb.2019.0210 Lixia Zhang, Leonardo O Rodrigues, Niven R Narain, Viatcheslav R Akmaev Structural learning of Bayesian networks (BNs) from observational data has gained increasing applied use and attention from various scientific and... SEPTEMBER 1, 2019 A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis Brain. 2019 Sept; 1;142(9):2756-2774 Wentling M, Lopez-Gomez C, Park HJ, Amatruda M, Ntranos A, Aramini J, Petracca M, Rusielewicz T, Chen E, Tolstikov V, Kiebish M, Fossati V, Inglese M, Quinzii CM, Katz Sand I, Casaccia... SEPTEMBER 1, 2019 Diablo ubiquitination analysis by sandwich immunoassay Journal of Pharmaceutical and Biomedical Analysis. 2019 Sept;173:40-46 Guven A, Wu WS, Patil S, Gokul K, Tekumalla P, Sharma S, Diers A, Gesta S, Vishnudas V, Sarangarajan R, Kellogg MD, Narain NR, Kiebish MA. Ubiquitin plays... JUNE 1, 2019 Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition. iScience. 2019 Jun;16:230-241 Haraszti RA, Miller R, Dubuke ML, Rockwell HE, Coles AH, Sapp E, Didiot MC, Echeverria D, Stoppato M, Sere YY, Leszyk J, Alterman JF, Godinho BMDC, Hassler MR, McDaniel J, Narain NR, Wollacott... MAY 1, 2019 Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course. EBioMedicine. 2019 May;43:392-410 Castro K, Ntranos A, Amatruda M, Petracca M, Kosa P, Chen EY, Morstein J, Trauner D, Watson CT, Kiebish MA, Bielekova B, Inglese M, Katz Sand I, Casaccia P. Multiple Sclerosis (MS) results... MAY 1, 2019 Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma. Communications Biology. 2019 May;2: 200 Mukherjee P, Augur ZM, Li M, Hill C, Greenwood B, Domin MA, Kondakci G, Narain NR, Kiebish MA, Bronson RT, Arismendi-Morillo G, Chinopoulos C, Seyfried TN. Glioblastoma (GBM) is an aggressive... FEBRUARY 1, 2019 A peroxidized omega-3-enriched polyunsaturated diet leads to adipose and metabolic dysfunction Journal of Nutritional Biochemistry. 2019 Feb;64:50-60 James L. Miller, Magdalena Blaszkiewicz, Cordell Beaton, Cory P. Johnson, Stephen Waible II, Amanda L. Dubois, Amanda Klemmer, Michael A. Kiebish, Kristy L. Townsend Consumption of diets that differ in... JANUARY 1, 2019 Genomic Alterations of Tenascin C in Highly Aggressive Prostate Cancer: A Meta-analysis Genes & Cancer. 2019;10(5-6):150-159 Prachi Mishra, Michael A. Kiebish, Jennifer Cullen, Alagarsamy Srinivasan, Aaliyah Paterson, Rangaprasad Sarangarajan, Niven R. Narain, Albert Dobi Tenascin C (TNC), an extra-cellular matrix (ECM) family gene, is expressed in several cancer... JANUARY 1, 2019 Omics Driven Medicine for Democratizing Healthcare Delivery and Health Economics Handbook of Biomarkers and Precision Medicine. 2019 Chapter 9.7, CRC Press Michael A. Kiebish, Viatcheslav R. Akmaev, Vivek Vishnudas, Stephane Gesta, Rangaprasad Sarangarajan, Niven R. Narain JANUARY 1, 2019 Identification of Biomarkers for the Diagnostics, Prediction, and Progression of Alzheimer’s Disease Handbook of Biomarkers and Precision Medicine. 2019 Chapter 8.7, CRC Press Bennett P. Greenwood, Vladimir Tolstikov, Paula P. Narain, Jeremy Chaufty, Viatcheslav R. Akmaev, Vivek Vishnudas, Stephane Gesta, Eric J. Nestler, Rangaprasad Sarangarajan, Niven R. Narain,... JANUARY 1, 2019 Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer Journal of Translational Medicine. 2019 Jan;18(1):10 Kiebish MA, Cullen, Mishra P, Ali A, Milliman E, Rodrigues LO, Chen EY, Tolstikov V, Zhang L, Panagopoulos K, Shah P, Chen EY, Petrovics G, Rosner IL, Sesterhenn IA, McLeod DG, Granger E, Sarangarajan R, Akmaev V, Srinivasan A, Srivastava S, Narain NR, Dobi A Predicting the clinical course of prostate cancer... JANUARY 1, 2019 Enabling biomarker discovery in Parkinson’s Disease Using Multiomics: Challenges, promise and the future Personalized Medicine. 2019 Jan;16(1):5-7 Michael A. Kiebish, Niven R. Narain Overview of the current state of biomarker discovery in Parkinson’s disease as well as the opportunity of using multi-omic discovery approach for engagement of novel biomarkers... Showing 21 of 80 publications - Page 1 of 4 1 2 3 4 Next Berg_Logo ABOUT US Leadership Team Founders Board of Directors Scientific Advisory Board RESEARCH & DEVELOPMENT Healthcare Professionals Our Pipeline Publications Patients and Caregivers Our Science Epidermolysis Bullosa (EB) Chemotherapy-Induced-Alopecia (CIA) Pancreatic Cancer Expanded Access and Compassionate Use Medical Resources Clinical Trials PARTNERS Pharmaceutical Healthcare Academic Government MEDIA News Features Press Releases Events Media Kit Clinical Trials CAREERS Join Our Team CONTACT Investor contact Media contact Partner contact Connect with us Headquarters and Innovation Center 500 Old Connecticut Path Framingham, MA 01701 Tel: (617) 588-0083 Email: Info@Berghealth.com © 2021 BERG LLCLEGAL Visit BERG on LinkedIn Visit BERG on Twitter Visit BERG on Facebook Visit the BERG YouTube channel