Your specialty Our products Why Biocomposites? Education Library News & Events Contact us Home Education Biofilm International Biofilm In this Biocomposites Biofilm Series, Professor Paul Stoodley answers some of the common questions surrounding the causes, impact and treatment of biofilm. You can also watch him answer some of the questions in our video series. Who is Paul Stoodley? 00:36 Who is Paul Stoodley? 00:36 What is a biofilm? 01:20 Should we always be concerned about biofilm? 01:16 What role does biofilm play in acute and chronic infections? 01:44 How long can biofilm remain dormant? 01:54 How do you treat biofilm? 02:57 Can you prevent biofilm forming? 02:37 Is there any difference in biofilm that forms on bone, soft tissue and implants? 01:09 Can implant design eliminate biofilm formation? 01:16 How effective are spacers in treating biofilm? 00:57 How effective are washouts in treating biofilm? 01:33 How do the antibiotic elution characteristics differ between calcium? 01:15 Biofilm - full interview 16:04 Professor Paul Stoodley PhD, Professor Microbial Infection and Immunity. ‘Surgeons are now starting to think of biofilms like cancer and that we must physically remove them….using surgical debridement with high levels of antibiotics and antimicrobial agents to break up and kill enough of the biofilm that our host immunity can then take care of the rest.’ Biofilm refers to a complex community of bacteria cells enclosed in a self-produced extracellular polymeric slime (EPS) matrix. Biofilm can adhere to inert or living surfaces. It can form on both foreign material and devitalized tissue. In vivo, biofilm can colonize, grow and cover a surface within 4-8 days. Biofilm is extremely hard to detect and eradicate and can be the cause of chronic disease. Biofilm is most often seen in soft tissue infections, chronic wounds and osteomyelitis. Q & A What is a biofilm? What are the symptoms of biofilm infection? What are the stages of biofilm formation? Should we always be concerned about biofilm? What role does biofilm play in acute and chronic infections? How long can biofilms remain dormant? How do you treat biofilm? Can you prevent biofilm from forming? Is there any difference in the biofilm that forms on bone, soft tissue and implants? Can implant design eliminate biofilm formation? How effective are washouts in removing biofilm? How effective are spacers in treating biofilm? How do the antibiotic elution characteristics differ between calcium sulfate and PMMA? Products genex® An innovative, versatile synthetic bone graft that supports natural healing and vanishes without a trace. View product > STIMULAN® Truly absorbable calcium sulfate antibiotic carrier approved for use in bone and soft tissue View product > MA0249R1 All rights reserved. No unauthorized copying, reproduction, distributing or republication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd. The opinions expressed in these videos and transcript are solely those of the presenter, they do not purport to reflect or represent the opinions or views of Biocomposites Ltd. Some comments relate to in vitro studies and may not correlate to clinical use. Your specialty Musculoskeletal infection Trauma Spine Sports injuries Our products STIMULAN® genex® Biosteon® Allogran-R® Bilok® Why Biocomposites? News & Events Contact us Education Biofilm Infected fractures Periprosthetic joint infection (PJI) Wound closure Our company COVID19 risk assessment Legal notices Sitemap Privacy statement Code of conduct Modern slavery statement Section 172 statement LinkedIn Twitter ©2021, Biocomposites. All rights reserved.