Product categories Resources Company Contact For investors For distributors Find a product for my lab Devyser CFTR NGS Full CFTR gene sequencing Single-tube NGS library prep kit CE-IVD View product Devyser CFTR 68 Detects 68 CFTR mutations Allele-specific detection CE-IVD View product Devyser CFTR Core Detects the 36 most common mutations found in populations of European origin Allele-specific detection of wild-type and variants View product Devyser CFTR Italia Designed for the Italian population Detects the normal and mutant alleles at 31 loci of the CFTR gene Includes ID markers for sample identity confirmation View product Devyser CFTR Iberia Designed for patients with Spanish and Portuguese ancestry Genotypes normal and mutant alleles at 15 loci of the CFTR gene Includes ID markers for sample identity confirmation View product Devyser CFTR UK Specifically designed for the UK population Genotypes normal and mutant alleles at 15 loci Includes ID markers for sample identity confirmation View product Cystic fibrosis A broad selection of genetic test kits for detection of variants in the CFTR gene. Allele-specific CFTR mutation detection and complete CFTR gene sequencing using NGS. CFTR mutation testing can be used in diagnosis of cystic fibrosis, male infertility caused by CBAVD, and acute recurrent or chronic pancreatitis. It can also be used to guide targeted therapies, and as an aid in newborn screening. More than 2,000 mutations and variants in the CFTR (cystic fibrosis transmembrane conductance regulator) gene have been described. The vast majority of these mutations have a population frequency below 0.1 % with high heterogeneity of mutation distribution between different ethnic groups. Devyser’s range of diagnostic CFTR kits enables allele specific detection as well as targeted, complete, CFTR gene sequencing using NGS for detection of all mutations, known and unknown, in a single test. The Devyser CFTR kits are easy to implement and highly cost-effective, making them a good match for laboratories of any size. With ready-to-use reagents and a user-friendly workflow, they suit both manual and automated workflows. Related articles Whitepaper: Next Generation Sequencing: Changing the game in CFTR analysis Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders – updated European recommendations ‍ Scientific publications F508del CFTR gene mutation in patients with allergic bronchopulmonary aspergillosis. M. N. Gamaletsou et al., J Asthma. 2018 Aug;55(8):837-843. Analysis of the CFTR gene inVenezuelan cystic fibrosis patients, identification of six novel cysticfibrosis-causing genetic variants. Sánchez K et al. Appl Clin Genet. 2016; 9:33–38. Results for life. Product categories Transplantation Thalassemias Oncology Fetal RHD screening NIPT Hereditary Cystic fibrosis Cardiovascular Male infertility Rapid aneuploidy analysis Accessories Resources Knowledge hub Whitepapers Tools IFU & certificates Company About us Teams Career News and events Privacy policy About cookies Contact Contact us Our offices Support Distributors © Devyser 2021