Products Services Solutions Resources Support Center Chinese Buxco Inhalation Exposure System Whether your study requires general or precise exposure, the Buxco FinePointe system helps you produce better results in less time. 2:23 Nose-Only Inhalation Tower System Produce reproducible results with precise, controlled lung deposition across all subjects with the Accumulated Inhaled Aerosol (AIA) parameter with the addition of plethysmography for collection of respiratory endpoints throughout exposure Get the highest quality data with the Buxco system designed to eliminate rebreathing of CO2 and uniform to all open ports. Cleaning and maintenance is a breeze with the stainless steel, stackable design. Save time by exposing up to 42 subjects simultaneously Learn more about the benefits of the FinePointe software platform Mass Dosing Buxco Mass Dosing Chambers are used to expose multiple subjects to an aerosol or gas when general dosing can be tolerated. Benefits of the Buxco chambers include: A perforated floor for for urine drainage Removable lid (no seal, should be used inside a containment hood) Two ports for aerosol or gas delivery Four luer ports for bias flow or other use Ability to hold approximately 15 mice, 6 rats or 2 guinea pigs. The Large Mass Dosing Chamber can hold approximately 25 mice, 10 rats or 4 guinea pigs Single Subject The Buxco system offers precise nose-only single subject exposure and general exposure through free roaming tubes. Nose-only: a cost effective version of the inhalation tower, enabling uniform exposure one subject at a time. Single Site Exposure Stations are available for mice, rats, and Hartley guinea pigs. Free-Roaming: single subject exposure for general dosing purposes. Smoke Generation and Delivery Turn-key options to deliver tobacco or vape smoke to subjects via traditional cigarettes, e-cigarettes, or vape devices. Multiple Applications and Derived Parameters With One System Model Development Safety Assessment Toxicology Expand all Tower & Plethysmograph Derived Parameters View the Tower Derived Parameters Table View Plethysmograph Derived Parameters Reference Publications Bosnjak B, Tilp C, Tomsic C, Dekan G, Pieper M, Erb K, EpsteinM. “Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice.” Pulmonary Pharmacology and Therapeutics. 2014;27:44-51. Glynn A, Alves D, Frick O, Erwin-Cohen R, Porter A, Norris S, Waag D, Nalca A. “Comparison of experimental respiratory tularemia in threenonhuman primate species.” Comparative Immunology, Microbiology and Infectious Diseases. 2015;39:13-24 Haapakoski R, Karisola P, Fyhrquist N, Savinko T, Wolff H, Turjanmaa K, Palosuo T, Reunala T, Lauerma A, Alenius H. “Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-gamma-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.” American Journal of Respiratory Cellular and Molecular Biology. 2011;44:639-647. Additional Information Webinar: Advancements in Buxco Inhalation Solutions from DSI Buxco Inhalation System Brochure AIA Tech Note Tower diagram Controller diagram Product Photo Gallery (Click image to enlarge) About DSI Contact US Our Story Harvard Bioscience Careers DSICare Newsroom Location Products Implantable Telemetry Respiratory Instrumentation Inhalation Instrumentation External Telemetry Signal Conditioners Software Product Warranty Resources Support Center Returning Products to DSI Blog Events Grant Writing Support Declaration of Conformity Sitemap Copyright 2021 Data Sciences International. Privacy Policy