CONTACT HOME ABOUT US RESEARCH AND TECHNOLOGY EDUCATION AND TRAINING CAREERS AND JOBS OUR EVENTS PRINCIPAL INVESTIGATORS Home Research and Technology Principal Investigators DEO faculty is composed of 23 Principal Investigators, whose complementary expertise in the fields of cancer biology, immunology/immunotherapy, genomics, epigenomics, transcriptomics, proteomics, cell signalling, cancer models, structural biology, molecular and pharmaco-epidemiology, cognitive and psychological science and computational biology ensures a comprehensive vision of cancer research. Myriam Alcalay Functional Genomics The advent of genomics in clinical practice is rapidly revolutionizing the approach to cancer prevention, diagnosis and therapy. Our objective... READ MORE Bruno Amati Oncogenes, Transcription and Cancer Our research aims at a better understanding of fundamental disease mechanisms and therapeutic opportunities in MYC-driven... READ MORE Tiziana Bonaldi Nuclear Proteomics to Study Gene Expression Regulation in Cancer We couple a strong technological attitude based on Mass Spectrometry (MS)-proteomics to the... READ MORE Ugo Cavallaro Unit of Gynecological Oncology Research Ovarian cancer (OC) remains an outstanding challenge in clinical oncology, mainly due to... READ MORE Susanna Chiocca Viruses and Cancer The overall focus of my research lab is to determine the mechanisms by which oncogenic viruses and other tumor microenvironmental stresses contribute to... READ MORE Pier Paolo Di Fiore Endocytosis, Signalling and Cancer Our multidisciplinary laboratory hosts projects in the fields of endocytosis, stem cells and functional genomics. Over recent years... READ MORE Federica Facciotti Mucosal Immunology My research group specifically focuses on understanding and functionally manipulating for therapeutic purposes the interactions between... READ MORE Sara Gandini Molecular and Pharmaco-Epidemiology Unit We work on primary and secondary cancer prevention projects, as well as on prognostics... READ MORE Luisa Lanfrancone Modeling and Targeting Metastatic Cancer The Lanfrancone Lab investigates how fundamental biological processes regulate... READ MORE Teresa Manzo Immunometabolism and Cancer Immunotherapy Cancer immunotherapy has been one of the major breakthroughsof cancer... READ MORE Marina Mapelli Molecular Basis of Asymmetric Cell Divisions The connection between deregulated stem cell divisions and tumorigenesis has been one of the... READ MORE Luca Mazzarella Translational oncology We believe that cancer can be understood and managed only by a multi-layered approach where methods proper of multiple disciplines... READ MORE Saverio Minucci Chromatin Alterations in Tumorigenesis Cancer cells show global changes in chromatin structure (DNA methylation and histone... READ MORE Gioacchino Natoli Transcriptional Control in Inflammation and Cancer The human genome contains more than 20.000 genes whose expression must be... READ MORE Luigi Nezi Microbiome and Antitumor Immunity There is a growing appreciation of the role of the microbiota in cancer-related outcomes and, in particular, response to immunotherapy. Our lab... READ MORE Diego Pasini Epigenetic Mechanisms in Cancer Control of cellular identity is regulated by a complex network of autonomous and non-cell autonomous signals that converge to the... READ MORE Salvatore Pece Hormone-Related Cancers and Stem Cell Pathobiology Our lab aims to understand the cellular and molecular basis of tumor heterogeneity in... READ MORE Giuliana Pelicci Biology of Glioblastomas and Brain Metastases and Potential Therapeutic Targets Unit Our research focuses on identifying and... READ MORE Pier Giuseppe Pelicci Molecular Mechanisms of Cancer and Aging Our group has traditionally focused on the elucidation of molecular and biological... READ MORE Stefano Santaguida Genome Integrity Genome integrity is maintained through faithful chromosome segregation at each cell division, in which one copy of a duplicated chromosome is... READ MORE Martin Hartmann Schaefer Computational Cancer Biology Lab We are interested how alterations of the DNA transform a healthy into a malignant cell. 10,000s of human genomes and epigenomes... READ MORE Nicola Segata Computational Metagenomics A healthy adult human harbours trillions of microbes that expand our own gene repertoire by at least two orders of... READ MORE Rosella Visintin Chromosome Segregation How do cells correctly inherit their chromosomes? Understanding how cells inherit a correct number of chromosomes during cell... READ MORE Giuseppe Testa High Definition Disease Modelling Lab: Stem Cell and Organoid Epigenetics The accelerated generation of multiple, digitally compatible datasets across scales of cellular and... READ MORE Istituto Europeo di Oncologia (IEO) Contact us Privacy policy Cookie policy Contact ®2021 Istituto Europeo di Oncologia - via Ripamonti 435 Milano - P.I. 08691440153 IEO.it Our site uses cookies for better browsing usability and statistics on its use. If you want to learn more, or refuse consent to all or some cookies, click here. I AGREE