Get the latest offers and updates from Lewis. Sign up to receive email alerts on Lewis weekly ads, coupons, in-store events and more. SIGN UP Newsletter Signup × SEARCH STORE MENU Black Friday Sneak Peek Make your list and check it twice! DEALS BLACK FRIDAYSANTA & REINDEERHoliday Look Book2021 Gift Guide2021 Toy Book Local Deals Get great deals on everyday favorites. Weekly Ad Our weekly ad is your first stop for savings! Pharmacy Refills We make getting your prescription filled easy. Find Your Store SEARCH EVENTS BLOG VIEW ALL Nov 26 Visit Santa & His Reindeer - Madison 9:00 am Don’t miss our Annual Live Reindeer Event at Lewis! Nov 26 Visit Santa & His Reindeer - Brookings 2:00 pm Don’t miss our Annual Live Reindeer Event at Lewis! Get the latest offers and updates from Lewis. Careers Contact About Employee Portal Need Help? (605) 367-2000 Download Our Apps MOBILE APPS Privacy Policy Coupon Policy Suppliers Info Garden Guarantee Gift Card Balance © 2021 Lewis Drug. All Rights Reserved Site by

SEARCH STORE MENU About Your first stop for over 79 years. Since 1942, shoppers have trusted family-owned Lewis as their neighborhood store and pharmacy. With 57 stores conveniently located throughout South Dakota, Iowa and Minnesota! In addition to quality prescription and non-prescription drugs, Lewis has a huge selection of everyday basics, plus name brands and specialty items—always at affordable prices. You’ll find everything on your list along with a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more. At Lewis, we promise you’ll be greeted with exceptional prices, friendly service and great products every time you walk through our doors. Make Lewis your first stop for all your family’s needs. Meet Our Executive Team It takes a dedicated team to keep Lewis bringing you everyday savings. Meet Our Executive Team. Questions or Comments? If you have any questions or concerns, please don’t hesitate to let us know. Contact us today. A Lewis representative will reach out to you shortly. Related Articles Looking Back: Lewis Drug December 16, 2015 | About On Feb. 10, 1942, South Dakota’s first self-service drugstore opened at 309 S. Phillips Ave. It was a little store called Lewis, and it occupied the space now run by CH Patisserie just south of Minerva’s. Get the latest offers and updates from Lewis. Careers Contact About Employee Portal Need Help? (605) 367-2000 Download Our Apps MOBILE APPS Privacy Policy Coupon Policy Suppliers Info Garden Guarantee Gift Card Balance © 2021 Lewis Drug. All Rights Reserved Site by