SEARCH LOGIN DONATE DONATE BLOOD PRODUCTS/SERVICES RESEARCH ABOUT US SUPPORT US NEWS COVID-19 RESEARCHINVESTIGATORS Xiuli An, MD, PhD Title Head, Laboratory of Membrane Biology Member, Lindsley F. Kimball Research Institute Research Area Our research focus is on developing a detailed molecular understanding of regulation of red cell production referred to as erythropoiesis. Erythropoiesis occurs exclusively in erythroid niches termed erythroblastic island (EBI) which is composed of a central macrophage surrounded by developing erythroid cells. Our lab has developed methods to purify both human and mouse erythroid cells at distinct developmental stages and methods to quantify the progress of erythroid differentiation in vivo. We have also developed methods to purify the EBI macrophages Through RNA-seq analysis, the lab has constructed global transcriptomes of human and murine erythroid cells as well as EBI macrophages. We are currently working on three main research areas: 1) regulation of erythropoiesis with focus on mechanisms for erythroblast enucleation; 2) how EBI macrophages regulate erythropoiesis; 3) Improving ex vivo red cell production from stem cells. Contact Information Email: XAn@nybc.org Phone: +1 (212) 570-3247 Lab Personnel Chengjie Gao, BS, Visiting Scientist, PhD Student Xinhua Guo, MS, Senior Research Associate Yongshuai Han, BS, Visiting Scientist, PhD Student Huan Zhang, BS, Visiting Scientist, PhD Student Funding Support NIH P01 HL149626 An (PI, Project 4) 07/20/2020 – 06/30/2025 "Hemolysis and the Hematopoietic Niche” NIH R01 HL140625 An, Lobo, Westhoff (Multi-PI) 12/15/2017-11/30/2021 "Use of forward genetic approaches to identify Babesia receptors” Education and Training Doctoral Training MD Henan Medical University, China PhD in Biochemistry, Tokyo Women’s Medical University, Japan Post-doctoral Training Molecular Biology and Cell Biology, Lawrence Berkeley National Laboratory, CA LIST OF PUBLICATIONS It takes more than blood to save a life MAKE A GIFT NEW YORK BLOOD CENTER New York Blood Center (NYBC) is one of the largest community-based, non-profit blood collection and distribution organizations in the United States. ©2021 New York Blood Center Privacy Policy Terms ABOUT NYBC Work Here Press Room NYBC Enterprises SUPPORT US Donate Blood Volunteer Make a Financial Contribution PRODUCTS & SERVICES Comprehensive Cell Solutions™ Hospital Customers Blood Products Laboratory Services Medical Services Clinical Services Blood Experts Blog Request Testing Kit GET CONNECTED Facebook Instagram LinkedIn Twitter Youtube CONTACT US 310 E 67th St New York, NY 10065 (212) 570-3000 Contact New York Blood Center BLOOD DRIVES VIEW TODAY'S DRIVES