FIXED-INCOME CORPORATE EVENTS GENERAL INFORMATION CORPORATE GOVERNANCE Institutional presentation Other presentations Shareholders Contact Investors Contact Universal Registration Document Significant equity shareholdings and treasury stock Offer to acquire outstanding shares and ADSs of Banco Santander Mexico (november 2021) History of Corporate Operations FAQs Institutional presentation 2021 Institutional Presentation 9M’21 5,3 MB Institutional Presentation H1’21 5,2 MB Institutional Presentation Q1’21 5,4 MB Other presentations 2021 28-04-2021 GSIBS Indicadores Cuantitativos (Only available in Spanish) 177,1 KB Shareholders Contact Santander Shareholder Relations www.santander.com accionistas@santander.com Shareholder Helpline: +34 91 276 92 90* WhatsApp: +34 91 276 92 90* Santander Group City. Av. Cantabria s/n 28660 Boadilla del Monte, Madrid (Spain) *Lines are open Monday to Friday from 8.00 a.m. to 7.00 p.m. and on Saturdays from 8.30 a.m. to 1:30 p.m. From 1 July to 30 September there will be no service on Saturdays. Holders of CREST Depositary Interests (CDIs) www.santandershareview.com santandershareholders@equiniti.com Shareholder Helpline: 0371 384 2000* *Lines are open Monday to Friday from 8.30 a.m. to 5.30 p.m. (excluding English and Welsh public holidays). Callers from overseas should contact +44 (0) 121 415 7188. Holders of American Depositary Receipts (ADRs) Citibank Shareholder Services PO Box 43077. Providence. RI 02940-3077 Phone: +1 888 810 7456 International phone: +1 781 575 4555 Lines open Monday to Friday 8:30am to 6:00pm EST citibank@shareholders-online.com www-us.computershare.com/investor MEET THE SHAREHOLDER RELATIONS TEAM Investors Contact INVESTOR RELATIONS TEAM Begoña Morenés GLOBAL HEAD OF SANTANDER SHAREHOLDER AND INVESTOR RELATIONS Carlos Berastain HEAD OF INVESTOR RELATIONS AND MARKET INTELLIGENCE EQUITY, FIXED INCOME & RATING AGENCIES Fernando Donoso INVESTOR RELATIONS Beatriz Serrano INVESTOR RELATIONS Gema Navamuel INVESTOR RELATIONS EQUITY, FIXED INCOME AMERICAS Paula Cricca SHAREHOLDER AND INVESTOR RELATIONS – US ESG Héctor Iturralde Tosin Iduh CORPORATE ACCESS COORDINATOR Marta Conde CONTACT THE INVESTOR RELATIONS TEAM AT: investor@gruposantander.com +34 91 259 65 14 Universal Registration Document This is the current Issuer Prospectus or Universal Registration Document (''Documento de Registro Universal'' formerly ''Folleto Informativo Continuado'' or ''Documento de Registro de Acciones''), which was registered with the National Securities Market Commission (''C.N.M.V.'') on the 30th March 2021. Universal Registration Document (PDF 21.2 Mb) (Only available in Spanish) First supplement to the Universal Registration Document (PDF 518 Kb) (only available in Spanish) Significant equity shareholdings and treasury stock Through the links provided below, you can access information shown in the public records of the Spanish Securities Market Commission (Comisión Nacional del Mercado de Valores or CNMV) on major holdings in Banco Santander’s share capital, significant shareholdings held by the Bank in other listed companies and the Bank’s treasury stock. In addition, there is link to the treasury stock policy. Major holdings in Banco Santander’s share capital, significant shareholdings held by the Bank in other listed companies and Bank’s treasury stock Treasury stock policy (PDF 777.3 Kb) Information related to Treasury Stock during 4Q20 and anual cash balances (PDF 188.2 Kb) Information related to Treasury Stock during 1Q21 (PDF 123.7 Kb) Information related to Treasury Stock during 2Q21 (PDF 123.5 Kb) Information related to Treasury Stock during 3Q21 (PDF 123.4 Kb) Offer to acquire outstanding shares and ADSs of Banco Santander Mexico (november 2021) The main documentation in connection with the offer conducted in the United States can be found below, while that in connection with the Mexican offer is accessible through here. Relevant Fact (PDF 137.3 Kb) US Offer to Purchase (PDF 695.8 Kb) Share Letter of Transmittal (PDF 2.5 Mb) ADS Letter of Transmittal (PDF 576.6 Kb) US form of acceptance (PDF 433.2 Kb) Letter to Brokers (PDF 111.6 Kb) Letter to Clients (PDF 119.8 Kb) Recommendation of the Board of Directors of Santander Mexico in connection with the tender offer (PDF 682 Kb) History of Corporate Operations Offer to acquire outstanding shares and ADSs of Banco Santander Mexico (August 2019) Banco Popular Acquisition Capital increase (July 2017) Historical information of Banesto Mergers Spin-offs Información pública de Popular Bolsa S.V., S.A.U. FAQs Santander share FAQ Dividends Group earnings General Shareholders' Meeting Shareholders' log USEFUL LINKS LEGAL LINKS OF INTEREST © Banco Santander S.A. All rights reserved. Corporate Headquarters: CGS Av. Cantabria s/n 28660 Boadilla del Monte, Madrid (Spain) COOKIE CONFIGURATION For Banco Santander, it is important to adapt to your tastes and preferences. 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