Home About Services Drug Discovery News Careers Contact Rodent Primary Neurons and Glia Culture Primary neuronal or glia cultures derived from wild-type or genetically engineered rodents represent a powerful tool to study mechanism of action and potential toxicity of compounds. Primary cultures also allow investigators to evaluate the effects of pharmaceutical agents, gene over expression, or transcript silencing, on neuronal development and survival, as well as changes in biomarkers expression. Figure 1: Primary cortical, hippocampal, and midbrain cells from embryonic day 18.5 (E18.5) C57BL/6 mouse. Cells were grown in vitro for 14 days. Immunocytochemistry staining were performed with Millipore MAB360 Anti-GFAP (Glial fibrillary acid protein) labeling Astrocytes, and Millipore AB5622 Anti-MAP-2 (microtubule-associated protein-2) labeling Neurons. Secondary antibodies used are from Invitrogen Alexa Fluor series. Cells were counterstained with DAPI (4′,6-diamidino-2-phenylindole), which fluorescently stain DNA. Imaging was performed on a Zeiss AXIO Imager A1 with a conjoining AxioCAM MRc5 and visualized using a 20 X objective. Want to get in touch? Connect with the PsychoGenics research team. Connect With Us CONTACT PsychoGenics Inc. 215 College Road, Paramus, NJ 07652 Email: info@psychogenics.com Phone: (914) 406-8019 Fax: (914) 406-8090 Privacy Policy Terms of Use Financial Conflict of Interest Policy Copyright ©2021 PsychoGenics Inc. All rights reserved. We are using cookies to give you the best experience on our website. You can find out more about which cookies we are using or switch them off in settings. Accept

Home About Services Drug Discovery News Careers Contact Schizophrenia & Mania View Fullscreen Want to get in touch? Connect with the PsychoGenics research team. Connect With Us CONTACT PsychoGenics Inc. 215 College Road, Paramus, NJ 07652 Email: info@psychogenics.com Phone: (914) 406-8019 Fax: (914) 406-8090 Privacy Policy Terms of Use Financial Conflict of Interest Policy Copyright ©2021 PsychoGenics Inc. All rights reserved. We are using cookies to give you the best experience on our website. You can find out more about which cookies we are using or switch them off in settings. Accept