Rumors that catfish contain cancer cells in social networks and word of mouth continue to spread. The impact of this issue that mothers are reluctant to buy catfish managed to summarize the comments of mothers who usually buy catfish for routine consumption as a side dish. Circulation of information that states that catfish contain cancer in pisu because of the life of catfish that can live in very dirty places though. The nickname as the filthiest fish refers to the nature of catfish that likes to consume various types of waste in the waters. In fact, an article that is quite vital on the internet mentions that human waste is also used as feed for a catfish cultivation in Haikou City, China. Based on these issues, in a mouthful of catfish meat, there are 3000 cancer cells. The issue quickly spread on social media and word of mouth. However, this issue has not dampened the sale of catfish in Medan and is still stable and has no effect. According to a number of traders in Medan and catfish farmers in the surrounding Medan, there is no effect of the issue on the consumption and sale of catfish. As admitted by Br Manalu, a catfish trader at Sukaramai Market, Medan. According to him, the sale of catfish remained stable and was not affected by the impact, related to the news, many people still consumed catfish. Sales of catfish remained normal and the price of catfish was also stable at Rp. 18000 per kilo, and it is very unfortunate with the news that catfish contains cancer cells, obviously this makes catfish farmers offended and we as traders will clearly find it difficult to find catfish supplies, he explained, Monday (16/11). A catfish farmer in the Medan Marelan area, Pujiono admitted that he did not affect the demand for catfish from his pond. Even the recent fish harvest has not been able to meet the market, the majority of which are sent to Aceh and the Medan market. Regarding catfish containing cancer cells, Community Nutrition Expert and Professor of Food and Nutrition at the Bogor Agricultural University (IPB), Prof. Dr. Ir Ali Khemsan MS, while in confirmation via cellular, Monday (16/11) denied the issue. He deeply regretted the news about cancer cell bacteria contained in catfish. In my opinion, the news is not true, in fact it makes catfish cultivators feel offended and devastated, because from there they can meet their needs, he explained. Instead, he said, the trigger for cancer cells was catfish frying oil. It is precisely what makes and causes cancer cells in people who fry something or even catfish themselves for sale using used cooking oil, that can trigger cancer. Therefore, it is hoped that all people will be more careful when buying food fried in oil, he concluded.