Patent Document ID: 9842194
Application ID: 14375810

Base Claim:
1. A method for estimating parameter values comprising: obtaining image data with an imaging apparatus; fitting a parameterized model function utilized to estimate myocardial blood flow and representing spillover by a scaling factor [ f v ( 1 - f v ) ⁢ K 1 ] where f v is a spillover fraction and K 1 is an influx value from the image data by: generating a N-dimensional grid, wherein N is a number of one or more terms that are non-linear in a parameter of the derived model function; pre-calculating the one or more non-linear terms given the parameter model function and the designated values of the non-linear parameters; calculating one or more remaining model terms of the parameter model function; and displaying at least one of the one or more non-linear and remaining linear model terms.

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Claim 2:
2. The method according to claim 1 , wherein the parameter model function is represented by y ⁡ ( t ) = [ v ⁡ ( T ) ⁢ ∫ e { - k 2 ⁡ ( t - T ) } ⁢ dT ] ⁡ [ f v ( 1 - f v ) ⁢ K 1 ] , wherein y(t) is the image data model, u(t) is an input activity, v(t) is a spillover activity, and k2 is an efflux value.