Patent Document ID: 20110104717
Application ID: 12910769
Patent Flag: 0

Claim One:
1. A method of diagnosing, prognosing, determining progression, predicting a response to a treatment or choosing a treatment in an individual, said method comprising: (1) classifying one or more hematopoietic cells in said individual by a method comprising: a) subjecting a cell population comprising said one or more hematopoietic cells from said individual to: no modulator, CD40L, H2O2, SCF, SDF-1α, TNFα, LPS, PMA, FLT3L and Thapsigargin, b) determining an activation level of p-Erk in one or more cells from said individual, and c) classifying said one or more hematopoietic cells based on said activation levels of p-Erk; and (2) making a decision regarding a diagnosis, prognosis, progression, response to a treatment or a selection of treatment in said individual based on said classification of said one or more hematopoietic cells.