Patent Document ID: 10162800
Application ID: 14051716
Patent Flag: 1

Claim One:
1. A system for determining a probability of achieving a pregnancy at a selected point in time, the system comprising: a central processing unit (CPU); and storage coupled to said CPU for storing instructions that when executed by the CPU cause the CPU to: accept as input, data representative of a plurality of fertility-associated phenotypic traits of a female subject; analyze the input data using a prognosis predictor generated by: obtaining a reference set of data from a plurality of women across one or more reproductive cycles, the reference set of data comprising fertility-associated phenotypic traits and known pregnancy outcomes, wherein the plurality of women accounts for a dropout population of women who ceased pregnancy attempts prior to reaching a live birth outcome and a non-dropout population of women who continued pregnancy attempts until live birth; determining one or more correlations between the at least one of the fertility-associated phenotypic traits and the known pregnancy outcomes at a plurality of time points across the reproductive cycles, wherein the dropout population is accounted for by estimating a likelihood of dropout for each subject at each reproductive cycle and weighing the women in the non-dropout population proportionally to the likelihood of dropout; and training the prognosis predictor on the reference set of data; provide a probability of achieving a pregnancy for the female subject at a selected point in time as a result of running the prognosis predictor on said input data; and treating the female subject with a fertility treatment based on the probability of achieving a pregnancy.