Patent Document ID: 20120221506
Application ID: 13464104
Patent Flag: 0

Claim One:
1. A non-transitory computer-readable storage medium storing a computer readable program of computer instructions, wherein the computer readable program when executed on a computer causes the computer to carry out the following operations: receiving a signature that is a collection of measurable node entities and their expected directions of change with respect to a reference node; and assessing a degree of activation of the signature by scoring one or more data sets against the signature to compute an amplitude score, where the amplitude score is computed from a differential data set, where the differential data set is a data set that has two conditions, a first condition, and a second condition; and wherein the first condition and the second condition are one of: a treated condition and a control condition, a disease condition and a non-diseased condition, a first disease condition and a second disease condition, a first patient population and a second patient population, a treatment with a first drug and the treatment with a second drug, a responder and a non-responder, pre- and post- drug treatment, pre- and post-development of a disease, and pre- and post-remission of a disease.