Patent Document ID: 7541448
Application ID: 11001785
Patent Flag: 1

Claim One:
1. An oligonucleotide comprising an internal axial molecular rod, wherein the molecular rod is a singly-linking axial molecular rod selected from the group consisting of an ethyne, a bicyclopentane, a bicyclooctane, acubane, a benzene, a napihalene, a pyrene, a pyridine, a phenylenc, a prophyrin, and combinations thereof, or a doubly-linking axial molecular rod selected from the group consisting of an ethylene, a cyclobutane, a cyclohexane, a cyclohexadiene, and combinations thereof, wherein the molecular rod is a rigid structure which does not bend and which covalently bonds two internal molecules of the oligonucleotide, one at each axial end of the rod, so that a distance between atoms of the two molecules covalently bound to the rod is fixed.