Patent Document ID: 9320900
Application ID: 11647700
Patent Flag: 1

Claim One:
1. A method of monitoring a subject, the method comprising: monitoring high frequency head vibration, muscle vibration, or speech production using an acoustic sensor mounted in the subject's head and coupled to a stimulating and recording circuit contained in an enclosure implanted in the subject; monitoring head movement and position with respect to gravity using an accelerometer mounted in the patient's head and coupled to the stimulating and recording circuit; delivering a first neuromodulation therapy with the stimulating and recording circuit to manage a neurological symptom of the subject, wherein the first neuromodulation therapy is specified by a first set of parameters derived at least in part from a comparison of a disease state estimate and a reference input corresponding to a target disease state, wherein the disease state estimate is based at least in part on a patient motion signal of the accelerometer and an acoustic signal of the acoustic sensor; recording the subject's response to the first neuromodulation therapy with the stimulating and recording circuit, the subject's response to the first neuromodulation therapy being calculated from a first set of data received from the accelerometer communicating with the subject and the acoustic sensor; wirelessly transmitting the subject's response to the first neuromodulation therapy from the stimulating and recording circuit to an external device that is external to the subject's body; delivering a second neuromodulation therapy with the stimulating and recording circuit, the second neuromodulation therapy specified by a second set of parameters, wherein the second set of parameters is defined by at least one parameter of the first set of parameters being automatically changed to a different value to provide the second set of parameters; recording the subject's response to the second neuromodulation therapy with the stimulating and recording circuit, the subject's response to the second neuromodulation therapy being calculated from a second set of data received from the accelerometer and the acoustic sensor; wirelessly transmitting the subject's response to the second neuromodulation therapy from the stimulating and recording circuit to the external device; and monitoring the responses to the first neuromodulation therapy and the second neuromodulation therapy from the external device.