Patent Document ID: 4880014
Application ID: 07160589
Patent Flag: 1

Claim One:
1. A method for determining a therapeutic drug dosage regimen for a biological subject which comprises the steps of: providing a first equation which relates at least one of the following personal characteristics, resistance, reactance, age, height, weight and sex of the subject, to a predictive value for volume of distribution (V) for a preselected drug in said subject; providing a second equation which relates at least one of the following personal characteristics, resistance, reactance, age, height, weight and sex of said subject, to a predictive value for elimination rate constant (K) for said preselected drug in said subject; determining the value of said personal characteristics of said subject which are related to said first equation for the predictive value for V; determining the value of said personal characteristics of said subject which are related to said second equation for the predictive value for K; calculating said predictive value of V using said first equation and said value of said measured personal characteristics related to said first equation; calculating said predictive value of K using said second equation and said value of said measured personal characteristics related to said second equation; determining a desired therapeutic concentration of said preselected drug for said subject; and calculating a dose and dosing interval to obtain said therapeutic concentrations of said drug using said calculated predictive values of V and K.