Patent Document ID: 20020142321
Application ID: 09940686
Patent Flag: 0

Claim One:
1. A method for achieving an optimal function of a biochemical reaction network in a cell comprising: (a) using optimization methods to calculate the optimal properties of a biochemical reaction network; (b) altering a listing of reactions in the biochemical reaction network and recomputing the optimal properties; (c) repeating b) until the desired optimal function is reached; (d) constructing the genetic makeup of a cell to contain the biochemical reactions which result from (c); (e) placing the cell constructed under (d) in culture under a specified environment to obtain a population of cells; and (f) cultivating the cells as in step (e) for a sufficient period of time and under conditions to allow the cells to evolve to the desired optimal function determined under (c), wherein the biochemical reaction network comprises a comprehensive biochemical reaction network.