Patent Document ID: 8178294
Application ID: 11564243
Patent Flag: 1

Claim One:
1. A method of determining that a human subject has a genetic predisposition for a biological condition, said method comprising: a) obtaining a biological sample from said subject, said sample containing nucleic acids from said subject; and b) detecting in said nucleic acids haplotype 12-1 in the lipoprotein lipase (LPL) gene, said haplotype 12-1 comprising: i) a T at the position corresponding to position 8393 of SEQ ID NO: 25; ii) a C at the position corresponding to position 9040 of SEQ ID NO: 25; iii) SEQ ID NO: 60, or the complement thereof, in exon 10 of the LPL gene; iv) SEQ ID NO: 64, or the complement thereof, in exon 10 of the LPL gene; v) SEQ ID NO: 68, or the complement thereof, m exon 10 of the LPL gene; vi) SEQ ID NO: 70, or the complement thereof, m exon 10 of the LPL gene; vii) SEQ ID NO: 72, or the complement thereof, m exon 10 of the LPL gene; viii) SEQ ID NO: 74, or the complement thereof, m exon 10 of the LPL gene; ix) SEQ ID NO: 78, or the complement thereof, m exon 10 of the LPL gene; x) SEQ ID NO: 80, or the complement thereof, m exon 10 of the LPL gene; xi) SEQ ID NO: 82, or the complement thereof, in exon 10 of the LPL gene; and xii) SEQ ID NO: 84, or the complement thereof; in exon 10 of the LPL gene; wherein said biological condition is a decreased risk of graft worsening and/or graft occlusion of a coronary artery bypass graft (CABG) and/or a decreased diastolic blood pressure (DBP).