Patent Document ID: 9708334
Application ID: 15306064
Patent Flag: 1

Claim One:
1. A compound of Formula I: (I), or pharmaceutically acceptable salts thereof, wherein R 1 is selected from the group consisting of: —CO 2 H, —C(O)N(R a ) 2 , —SO 2 (C 1-4 alkyl), —SO 2 CH 2 (C 3-6 cycloalkyl), —CN, where each R a is independently —H, or —C 1-3 alkyl; R 2 is selected from the group consisting of: —H, halo, —C 1-3 alkyl, —C 1-3 haloalkyl, —C 1-3 alkoxy, and —CN; R 3 is selected from the group consisting of: (a) —H, —C 1-6 alkyl, —C 1-6 haloalkyl, —(C 1-3 alkyl) 0-1 C 3-6 cycloalkyl, or —(C 1-3 alkyl) 0-1 heterocycloalkyl; (b) benzyl or phenyl, wherein the phenyl is unsubstituted or substituted with one to three members each independently selected from the group consisting of: halo, —C 1-4 alkyl, —C 1-4 haloalkyl, —C 1-6 alkoxy, and —CN; and (c) monocyclic five or six membered heteroaryl ring containing one to three nitrogen members, unsubstituted or substituted with one to three members each independently selected from the group consisting of: —C 1-6 alkyl, —C 1-6 haloalkyl, —C 1-3 alkoxy, —C 1-3 haloalkoxy, —C 3-6 cycloalkyl, and —CN; R 4 is selected from the group consisting of: —H, —F, —C 1-4 alkyl, —C 1-4 haloalkyl, —C 1-4 alkoxy, —OH, phenyl, and 4-trifluoromethylphenyl; R 5 is selected from the group consisting of: (a) —C 1-6 alkyl, —C 1-6 haloalkyl, —OC 1-6 alkyl or —OC 1-6 haloalkyl; (b) —(C 1-3 alkyl) 0-1 C 3-6 cycloalkyl, —(C 1-3 alkyl) 0-1 heterocycloalkyl, —O(C 1-3 alkyl) 0-1 C 3-6 cycloalkyl, —O(C 1-3 alkyl) 0-1 heterocycloalkyl, or —O(C 1-3 haloalkyl) 0-1 C 3-6 cycloalkyl, wherein each cycloalkyl member is unsubstituted or substituted with one to three members independently selected from the group consisting of: -D, —F, —OC 1-3 alkyl, and —C 1-4 haloalkyl, wherein each heterocycloalkyl member is a four, five, or six membered monocyclic ring, unsubstituted or substituted with one to three members each independently —F, or —C 1-6 alkyl; and (c) phenyl or pyridyl, each unsubstituted or substituted with one to three members each independently selected from the group consisting of: halo, —C 1-6 alkyl, and C 1-6 haloalkyl; X is —(CR b ) 1-2 —; and each R b is independently —H, or —C 1-3 alkyl.