Patent Document ID: 9347102
Application ID: 13913077
Patent Flag: 1

Claim One:
1. A signature set of full length complementary DNAs (cDNAs) for predicting risk of developing therapy-related myelodysplasia or acute myeloid leukemia (t-MDS/AML) after autologous hematopoietic cell transplantation (aHCT), wherein the full length cDNAs are amplified from RNA that is expressed by genes present in a biological sample, and are associated with the development of t-MDS/AML, wherein said genes consist of REEP1, ACTL6A, GOLPH3L, CCDC99, PDIA4, GOT1, XPOT, ZYG11B, ARL61P6, NRIP3, NR4A2, FOS, EGR1, CARD6, PEX11B, EGR3, EGR4, MRPL15, SLC7A11, FOSB, GOLGA5, SMAD7, SHMT2, LRPPRC, CDCA4, RTN3, KLF2, JUN, STK17B, PSMC2, LRBA, ZNF137, GEM, PGRMC2, SLC2A3P1, NR4A3, RGS2 and SLC26A2.