Patent Document ID: 20030215786
Application ID: 10287173
Patent Flag: 0

Claim One:
1. A method for identifying one or more components of a cell as putative targets for interaction with one or more agents, comprising the steps of: (a) specifying a biochemical network believed to be intrinsic to a phenotype of said cell; (b) simulating said network by (i) specifying the components of said network, and (ii) representing interrelationships between said components in one or more mathematical equations; (c) solving the mathematical equations to simulate a first state of the cell; (d) perturbing the simulated network by deleting one or more components thereof, changing the concentration of one or more components thereof or modifying one or more mathematical equations representing interrelationships between one or more of said components; (e) solving the equations representing the perturbed network to simulate a second state of the cell; and (f) comparing said first and second simulated states of the network to identify the effect of said perturbation on the state of the network, and thereby identifying one or more components for interaction with one or more agents.