Patent Document ID: 20040152075
Application ID: 09909317
Patent Flag: 0

Claim One:
1. A genetic testing method for systemic lupus erythematosus (SLE) in a human subject, comprising: a) collecting a tissue sample from a human subject; b) amplifying nucleic acids from said tissue sample to obtain amplification products, said nucleic acids comprising a genomic sequence of human chromosome 1 between microsatellite markers D1S2860 and D1S213; and c) detecting in the amplification products the presence or absence of a twelve-fold CA dinucleotide repeat sequence consisting of (SEQ. ID. NO.:6), wherein said CA dinucleotide repeat sequence is located in the genomic sequence upstream from a PARP transcription start site, corresponding to nucleotide positions 846 through 869 of (SEQ. ID. NO.:5), and wherein the presence of said CA dinucleotide repeat sequence is diagnostic of SLE in a subject having SLE symptoms or indicates a genetic predisposition to develop SLE in a subject not presenting SLE symptoms.