Patent Document ID: 9939533
Application ID: 14678550
Patent Flag: 1

Claim One:
1. A system for the ex vivo real-time detection of gamma radiation emitted by a subject from administration and uptake over a period of time of a radioactive analyte that decays in vivo by positron emission, the system comprising: at least one ex vivo measurement sensor having a sensor housing, a scintillation material, a light detector, a temperature sensor, a signal amplifier, and a sensor power source, the light detector, temperature sensor, signal amplifier, and sensor power source in operable communication, the scintillation material and light detector disposed within the sensor housing in a light proof manner, with the scintillation material adapted to receive a level of gamma radiation over the period of time from the in vivo radioactive analyte and to emit photons representative of the gamma radiation level, the light detector disposed with respect to the scintillation material to receive and convert the photons into signal data representative of the frequency level over time of gamma radiation received, the signal amplifier adapted to amplify the signal data, the measurement sensor having at least one sensor output for such amplified signal data; at least one computer processor having a non-transient memory and a clock, the computer processor in operable communication with the measurement sensor; wherein the memory includes control computer program code executable by the at least one computer processor, the control computer program code including a first module for measurement, a second module for data management; wherein the first module is adapted to receive the signal data in a record file format; a temperature compensator coupled with the temperature sensor, the temperature sensor adapted to measure an ambient temperature with the system adapted to communicate the ambient temperature to the temperature compensator, such that the temperature compensator is adapted to generate a temperature correction factor based on comparison of the ambient temperature to a reference temperature, the temperature compensator further adapted to apply the temperature correction factor to the signal data to produce temperature compensated signal data; wherein the second module is adapted to receive the signal data of a record file from the first module and to transmit the compensated signal data to a desired storage; and wherein the computer program code further comprises a third module adapted to receive stored data of a record file from the second module, to apply such stored data to calculate changes in the compensated signal data over a desired period, to apply stored data to a predictive model to generate predictive data values over a desired period for such record file as a predictive outcome, and to transmit such changes to a desired storage.