Patent Document ID: 10036758
Application ID: 12715259
Patent Flag: 1

Claim One:
1. A method of delivering a light activated cation channel into a brain of a subject, the method comprising: a) administering directly to a portion of a brain in a subject a viral vector comprising a nucleotide sequence encoding a light activated cation channel that comprises an amino acid sequence having at least about 95% amino acid sequence identity to the amino acid sequence set forth in SEQ ID NO: 1, wherein said nucleotide sequence is operably linked to a promoter that provides for expression of the light activated cation channel in a neuron in the portion of the brain, and wherein the portion of the brain is one or more of the anterior cingulate cortex, the subgenual anterior cingulate cortex, and the anterior limb of internal capsule; b) introducing a light source near the portion of the brain; and c) activating the light activated cation channel in the neuron using light from the light source.