Patent Document ID: 20060160877
Application ID: 10516777
Patent Flag: 0

Claim One:
1. A compound of the formula in which R 1 is 1-azabicyclo[2.2.2]oct-3-yl, which is optionally substituted via the nitrogen atom by a radical selected from the group of C 1 -C 4 -alkyl, benzyl and oxy, R 2 is hydrogen or C 1 -C 6 -alkyl, R 3 is hydrogen, halogen or C 1 -C 6 -alkyl, R 4 is hydrogen, halogen, cyano, amino, trifluoromethyl, trifluoromethoxy, C 1 -C 6 -alkyl, C 1 -C 6 -alkylcarbonyl, C 1 -C 6 -alkylamino, formyl, hydroxycarbonyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkoxycarbonyl, C 1 -C 6 -alkylthio, C 1 -C 6 -alkylcarbonylamino, C 1 -C 6 -alkylaminocarbonyl, C 1 -C 4 -alkylsulphonylamino, C 3 -C 8 -cycloalkylcarbonylamino, C 3 -C 6 -cycloalkylaminocarbonyl, pyrrolyl, C 1 -C 6 -alkylaminocarbonylamino, heterocyclylcarbonyl, heterocyclylcarbonylamino, heteroarylcarbonylamino, hydroxyl, phenyl or heterocyclyl, where C 1 -C 6 -alkyl may optionally be substituted by hydroxyl, cyano, amino, C 1 -C 6 -alkylaminocarbonylamino, C 1 -C 6 -alkylaminocarboxyl, heterocyclyl or aryl, C 1 -C 6 -alkylaminocarbonyl may optionally be substituted by C 1 -C 6 -alkoxy or C 1 -C 6 -alkylamino, C 1 -C 6 -alkylcarbonylamino may optionally be substituted by C 1 -C 6 -alkoxy, and heterocyclyl may optionally be substituted by oxo, A is oxygen or sulphur, the ring B is benzo or pyrido, each of which are optionally substituted by radicals from the series halogen, cyano, formyl, trifluoromethyl, trifluoromethoxy, nitro, amino, C 1 -C 6 -alkyl and C 1 -C 6 -alkoxy, and E is C≡C, arylene and heteroarylene, where arylene and heteroarylene may be substituted by radicals from the series halogen, cyano, trifluoromethyl, trifluoromethoxy, nitro, amino, C 1 -C 6 -alkoxy and C 1 -C 6 -alkyl, and the solvates, salts or solvates of the salts of these compounds.