Patent Document ID: 8076084
Application ID: 12406379
Patent Flag: 1

Claim One:
1. A method of predicting prognosis or overall survival of a non-small cell lung cancer (NSCLC) patient, comprising: obtaining a biological sample from the cancer patient; performing a detection sequence to detect HIF-1α marker; performing a detection sequence to detect TWIST marker or Snail marker; if HIF-1α and TWIST are co-expressed in the biological sample at a level higher than in a control sample known to lack expression of these markers, determining that the patient is an elevated risk for having non-small cell lung cancer; and if HIF-1α and Snail are co-expressed in the biological sample at a level higher than in a control sample known to lack expression of these markers, determining that the patient is an elevated risk for having non-small cell lung cancer wherein co-expression of said HIF-1α and TWIST or said HIF-1α and Snail markers in the biological sample indicates poor prognosis or overall survival of the cancer patient.