Patent Document ID: 9249463
Application ID: 13927389
Patent Flag: 1

Claim One:
1. A method of detecting a variant angiogenin (ANG) nucleic acid in a biological sample, which method comprises a. assaying the biological sample from a human subject with an oligonucleotide which specifically binds to a mutation in an ANG nucleic acid selected from the group consisting of A191T, A107T, A121G, G164A, C189G, and A208G, wherein the position of the mutation is calculated from the first nucleotide of the cDNA sequence encoding a full angiogenin transcript (SEQ ID NO:17), b. detecting hybridization of the oligonucleotide with the ANG nucleic acid, and c. detecting a variant ANG nucleic acid in the sample when hybridization is detected in step (b).