Patent Document ID: 9649358
Application ID: 14362891
Patent Flag: 1

Claim One:
1. A method for treating a lesion in the post-embryonic spinal nerves of a subject, the method consisting essentially of; (a) administering treatment to the spinal nerves by grafting human pluripotent neural stem cells evenly distributed throughout a transplantation matrix comprising fibrin together with brain-derived neurotropic factor (BDNF) into the lesion or no more than up to 1 mm away therefrom by injection or infusion; (b) determining pre- and post-treatment locomotor function in the subject, wherein, notwithstanding the inhibitory mileau of chondroitin sulfate proteoglycan in the spinal cord, stimulated axonal growth in response in the locomotor function of spinal nerves from the lesioned site in the subject comparable to significant improvement on the Basso, Beattie, and Bresnahan (BBB) scale.