Patent Document ID: 20120046283
Application ID: 13140694
Patent Flag: 0

Claim One:
1. A compound having the structure of Formula V or pharmaceutically acceptable salt or N-oxide thereof: wherein: W is a bond; R 6 is H, or halogen; R 7 is H, halogen, CN, OH, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, —C(═O)N(R 10 ) 2 , CO 2 R 10 , N(R 10 ) 2 , acyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; Q is substituted or unsubstituted cycloalkyl or heterocycloalkyl fused to ring A; ring A is substituted or unsubstituted aryl or heteroaryl substituted with 0-4 R 4 ; each R 4 is independently halogen, —CN, —NO 2 , —OH, —SR 8 , —S(═O)R 9 , —S(═O) 2 R 9 , —NR 10 S(═O) 2 R 9 , —S(═O) 2 N(R 10 ) 2 , —C(═O)R 9 , —OC(═O)R 9 , —CO 2 R 10 , —N(R 10 ) 2 , —C(═O)N(R 10 ) 2 , —NR 10 C(═O)R 10 , —NR 10 C(═O)OR 10 , —NR 10 C(═O)N(R 10 ) 2 , substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl or substituted or unsubstituted heterocycloalkyl; R 8 is H or substituted or unsubstituted alkyl; R 9 is substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl each R 10 is independently H, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl, or two R 10 together with the atoms to which they are attached form a heterocycle; ring B is aryl or heteroaryl substituted with R 5 ; each R 5 is independently halogen, —CN, —NO 2 , —OH, —SR 8 , —S(═O)R 9 , —S(═O) 2 R 9 , NR 10 S(═O) 2 R 9 , —S(═O) 2 N(R 10 ) 2 , —C(═O)R 9 , —OC(═O)R 9 , —CO 2 R 10 , —N(R 10 ) 2 , —C(═O)N(R 10 ) 2 , —NR 10 C(═O)R 10 , —NR 10 C(═O)OR 10 , —NR 10 C(═O)N(R 10 ) 2 , substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl or substituted or unsubstituted heterocycloalkyl; r is 0-8; provided that when Q is unsubstituted indane, tetrahydronaphthalene or fluorene, and R 6 is H, ring B is not unsubstituted phenyl and R 5 is not para substituted piperidinyl, pyrazolyl or methylpiperazinyl.