Patent Document ID: 8435949
Application ID: 13493514
Patent Flag: 1

Claim One:
1. A method of enhancing neurogenesis in a mammal in need thereof, comprising administering an effective amount of 1) a luteinizing hormone (LH), a human chorionic gonadotrophin (hCG), or combination thereof, and 2) a neural stem cell growth agent, a neural stem cell differentiation agent, or a combination thereof to the mammal, wherein neurogenesis is enhanced in the mammal; wherein the neural stem cell growth agent is selected from the group consisting of follicle-stimulating hormone (FSH), growth hormone (GH), insulin growth factor (IGF), growth hormone releasing hormone (GHRH), prolactin, prolactin releasing peptide (PRP), fibroblast growth factor (FGF), estrogen, serotonin, epidermal growth factor (EGF), transforming growth factor alpha (TGFα), gonadotropin releasing hormone (GnRH), ciliary neurotrophic factor (CNF), and leukemia inhibitory factor (LIF); and wherein the neural stem cell differentiation agent is selected from the group consisting of erythropoietin (EPO), brain derived neurotrophic factor (BDNF), transforming growth factor beta (TGFβ), bone morphogenic protein (BMP), thyroid hormone (TH), thyroid stimulating hormone (TSH), thyroid releasing hormone (TRH), sonic hedgehog (SHH), platelet derived growth factor (PDGF), cyclic AMP, pituitary adenylate cyclase activating polypeptide (PACAP), and serotonin.