Patent Document ID: 20080032291
Application ID: 11564243
Patent Flag: 0

Claim One:
1. A method of determining a genetic predisposition for a biological condition in a human subject, comprising: a) collecting a biological sample from the subject; b) genotyping the sample at nucleotide positions selected from rs320 (8393), rs328 (9040), rs11570891, rs3289, rs1803924, rs1059507, rs3735964, rs3200218, rs1059611, rs10645926, rs15285, and rs3866471; and c) assessing whether haplotype 1 (1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1), haplotype 2 (1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 1), or haplotype 4 (2, 2, 2, 1, 2, 1, 2, 1, 2, 2, 2, 1) is present in the sample, wherein the presence of haplotype 1 indicates an increased probability of insulin sensitivity in the subject and the presence of haplotype 2 or haplotype 4 indicates an increased risk of developing insulin resistance in the subject.