Patent Document ID: 20170211029
Application ID: 15011385
Patent Flag: 0

Claim One:
1. A neurovascular unit (NVU)-on-a-chip, comprising: an extracellular matrix (ECM) simulation material ( 70 ) in a gel state; and at least one channel ( 75 ) which passes through the ECM simulation material ( 70 ) and perfuses a culture medium, wherein the ECM simulation material ( 70 ) includes a plurality of types of human brain cells on an outer side of the channel ( 75 ), a brain microvessel endothelial cell lining ( 91 ) is formed on an inner side of the channel ( 75 ), and the plurality of types of human brain cells and the brain microvessel endothelial cell lining ( 91 ) contact each other through the channel ( 75 ) to simulate a blood brain barrier (BBB) of a human brain and a neurovascular unit (NVU) of the human brain including the BBB.