Patent Document ID: 10108776
Application ID: 14301069
Patent Flag: 1

Claim One:
1. A computerized trajectory-based method to represent translocon-associated protein trajectories, comprising: i) representing, by a processor, amino acids corresponding to a protein and an associated translocon as a plurality of coarse grain particles; ii) representing, by a processor, confinement and driving force effects of an active protein inserter; iii) representing, by a processor, interactions between the coarse grain particles; iv) calculating, by a processor, evolution of a chain of the coarse grain particles corresponding to the protein in the translocon as a function of time, with a translation rate of at least 6 res/s; v) based on steps i)-iv), building, by a processor, translocon-associated protein trajectories; and vi) providing, by a processor, spatial representation of the translocon-associated protein trajectories to a user.