Patent Document ID: 8609733
Application ID: 12993622
Patent Flag: 1

Claim One:
1. A method for selective sensory nerve blockade comprising administering a combination of effective amounts of a charged local anesthetic selected from the group consisting of local anesthetics of Formula I: where R 1 -R 5 are independently selected from linear or branched alkyl groups, and a chemical permeation enhancer selected from the group consisting of sulfoxide decylmethylsulfoxide (C 10 MSO); diethylene glycol monoethyl ether, dekaoxyethylene-oleylether, diethylene glycol monomethyl ethers; sodium lauryl sulfate (SLS), sodium octyl sulfate (SOS), dodecyltriethylammonium bromide (DDAB), octyltriethylammonium bromide (OTAB), and polysorbate, in a suitable pharmaceutically acceptable carrier to selectively increase or prolong the duration of sensory block, without affecting motor block.