Patent Document ID: 20090148431
Application ID: 12368838
Patent Flag: 0

Claim One:
1. A method of modulating production of neurons and/or oligodendrocytes from human white matter neural progenitor cells, said method comprising: administering, to human white matter neural progenitor cells, an agonist or antagonist of one or more molecules selected from the group consisting of BMP2, BMP7, FRZB, NELL1, NELL2, NRLN1, PTN, SLIT1, CHGB, CLU, MMP16, PRSS11, SCG2, SERPINE2, TIMP4, CNR1, FGFR3, GABBR1, GABRB1, GLRB, GPR19, GRIA2, GRIA3, GRIK1, GRIK2, KLRC3, LDLR, LRP1, PDGFRA, TM4SF2, TM4SF6, ACK1, ADCY8, ARHGEF4, ARHGEF6, ARL7, CAP2, CASK, DOK5, INSIG1, JIK, MAB21L1, MAGED1, NMA, PKIA, PPAP2B, RAB31, SHC3, SIAH1, SPRY2, ASTN, CDH11, CDH13, CDH18, CHL1, CLDN10, CLSTN1, DSCAM, FLRT2, GPM6A, ITGA7, KIAA1775, NCAM1, NLGN1, NRCAM, OPCML, PCDH8, SDC3, BGN, COL11A1, COL16A1, CRTL1, CSPG2, CSPG3, CSPG4, CSPG5, PTPRZ1, SPARCL1, THBS2, THBS4, TNR, ALDH1A3, ALDH5A1, ALDOC, B3GNT6, BAAT, CHST10, CKMT1, CPE, DUSP8, ELOVL5, GAD1, GLDC, H105E3, HMGCR, IDI1, KIAA0455, LCK, MOXD1, NME4, PDE8B, PFKM, PGM1, PRDX2, PTPN4, SC4MOL, SIAT8A, TRB2, ASCL1, CROC4, FHL1, FOXG1B, HCFC1, HES1, HLF, ING3, JUN, LHX2, NFIB, NR2F1, NRF, SOX13, SOX4, SOX5, ZFP36L2, ABCC8, ACCN2, ACTC, AF1Q, APOD, ATP1A2, ATP1B2, ATP2A2, ATP2B4, BASP1, BC008967, BSCL2, C11orf8, CADPS, CCND1, COG4, CRMP1, CRY1, D2S448, DCX, DNAJB1, DPYSL3, DZIP1, EEF1A2, EMU1, EPM2AIP1, EPN2, F3, FLJ13310, GAP43, HIS1, HSPH1, ITM2A, KCNB1, KCND3, KIAA0062, KIAA0354, KIAA0888, KIAA0931, KIAA0992, LAPTM4B, LOC348155, LOH11CR2A, LPHN3, MAP2, MEG3, MID1, N33, NCALD, NEBL, NICE-4, NPD009, NPIP, OIP106, OLFM1, PARD3, PCF11, PDE4DIP, PDZK3, PER1, PER2, PM5, PNMA2, ProSAPiP1, RAMP1, RARRES2, RBBP6, SCRG1, SEMA5A, SEMACAP3, SEZ6L, SLC1A1, SLC1A2, SMARCD3, SRPX, SYT11, TARBP1, THY1, TNKS, TRB@, TRIM9, TRO, TUBB, USP24, YAF2, CCL20, FGF1, GRN, IL1B, IL1RN, C3AR1, FCGR2A, IL10RA, LILRB4, CCR1, CCR5, CCRL2, DOK1, LYN, MPP1, SOCS4, BLVRB, GPX1, GSTO1, KYNU, LIPA, MEP1A, PTP4A2, HIF1A, TFEC, PPARG, CLIC1, FER1L3, KIAA0053, LOC253982, LPXN, LY86, TRIM44, APOC2, BCL2L2, FABP4, GAS7, HBA1, HBG1, HLA-DPA1, HLA-DQB1, HLA-DRB1, KIF1C, LCP1, LCP2, LGALS1, PXR1, RNASE6, S100A11, TRIM38, and UCP2 under conditions effective to modulate production of neurons and/or oligodendrocytes.