Patent Document ID: 9153024
Application ID: 14449852
Patent Flag: 1

Claim One:
1. A method for predicting spatial and temporal distributions of therapeutic substance carriers within a body, comprising: at a computing system, receiving an image dataset and a spectra dataset of a drug carrier; at the computing system, transforming the image dataset and the spectra dataset into a set of characteristics, wherein the set of characteristics comprises electrotopological characteristics, connectivity characteristics, molecular characteristics, and geometrical characteristics; generating a set of descriptors based upon the set of characteristics and a set of encoding functions; at the computing system, transforming the set of descriptors into a set of pharmacokinetic parameters and a set of pharmacodynamic parameters for the therapeutic substance carrier based upon a transformation model; at the computing system, transforming the set of pharmacokinetic parameters and the set of pharmacodynamic parameters into a spatial distribution and a temporal profile of the therapeutic substance carrier based upon a predictive model; and mapping the spatial distribution and the temporal profile onto at least a portion of an organ system of the user, thereby characterizing at least one of a concentration of the therapeutic substance carrier and a concentration of a therapeutic substance carried by the drug carrier in the organ system within a time window.