Patent Document ID: 20120040381
Application ID: 13282111
Patent Flag: 0

Claim One:
1. A method of identifying a subject having one or more diseases, the method comprising: determining a level of soluble ST2 in a biological sample from the subject; determining a level of one or more adjunct biomarkers selected from the group consisting of: N-terminal (NT)-pro-brain natriuretic peptide (BNP), proBNP, BNP, NT-pro-atrial natriuretic peptide (ANP), proANP, ANP, cardiac troponin I, cardiac troponin T, D-dimers, C-reactive protein, IL-6, albumin, creatinine, alanine transaminase, aspartate transaminase, alkaline phosphatase, total bilirubin, bacterial endotoxin, and blood urea nitrogen in a biological sample from the subject; comparing the level of soluble ST2 in the subject to a reference level of soluble ST2; comparing the level of the one or more adjunct biomarkers in the subject to a reference level of the one or more adjunct biomarkers; wherein an increase in the level of soluble ST2 compared to the reference level of soluble ST2 and an increase in the level of the one or more adjunct biomarkers in the subject to a reference level of the one or more adjunct biomarkers indicates that the subject has one or more diseases.