Patent Document ID: 20130310678
Application ID: 13886016
Patent Flag: 0

Claim One:
1. A method of reconstructing an MRI or ultrasound biomedical image, based on compressed sensing and comprising the steps of: a) exciting a body under examination with radiofrequency (RF) or ultrasound (US) pulses for generating signals; b) acquiring image data from said generated signals, wherein said signals are acquired by pseudo-random undersampling; c) reconstructing said image using a nonlinear iterative algorithm for minimizing an optimization function containing a term for image data sparsity in a predetermined domain and a term for finite differences of the image, with a data fidelity constraint term ensuring fidelity to the acquired image data; wherein two or more sets of image data are acquired from said generated signals, the index of each image data set being i in the equation below, each data set being acquired in a different undersampling scheme, denoted by u i in the equation below, and/or a different acquisition mode such as to make expected and unavoidable artifacts incoherent; each of the acquired image data set is multiplied by a correction matrix Δ i , which is calculated from a mathematical model of expected artifacts according to prior knowledge of such artifacts, for adjusting said fidelity term in such a way that the fidelity term ensures fidelity of the reconstructed image to the corrected acquired image data as in the following equation: f = ∑ i  F u i m - Δ i y i  2 + λ 1  Ψ m  1 + λ 2 TV ( m ) ; for each iteration of said nonlinear iterative algorithm the data sets are processed to generate a combination image m which will therefore be faithful to the acquired data but not to the incoherent artifacts, thereby leading to suppression of said artifacts.