Patent Document ID: 5589376
Application ID: 08290228
Patent Flag: 1

Claim One:
1. An isolated population of mammalian neural crest stem cells, wherein said cells are capable of self-renewal in a feeder cell-independent culture medium and capable of differentiation to peripheral nervous system neuronal or glial cells, wherein said neural crest stem cells express low-affinity nerve growth factor receptor (LNGFR) and nestin, but do not express glial fibrillary acidic protein (GFAP), wherein at least one of said isolated population is capable of differentiation to a peripheral nervous system neuronal cell that does not express LNGFR or nestin but does express neurofilament-160, and wherein at least one cell of said isolated population is capable of differentiation to a peripheral nervous system glial cell that expresses LNGFR, nestin and GFAP.