Patent Document ID: 10007766
Application ID: 15207825
Patent Flag: 1

Claim One:
1. A method of detecting a class label in a melanoma patient comprising: a) conducting mass spectrometry on a blood-based sample of the patient and obtaining mass spectrometry data; (b) obtaining integrated intensity values in the mass spectrometry data of a multitude of mass-spectral features, wherein the mass-spectral features include a multitude of features listed in Appendix A, Appendix B or Appendix C; and (c) operating on the mass spectral data with a programmed computer implementing a classifier; wherein in the operating step the classifier compares the integrated intensity values with feature values of a reference set of class-labeled mass spectral data obtained from blood-based samples obtained from a multitude of other melanoma patients treated with an antibody drug blocking ligand activation of programmed cell death 1 (PD-1) with a classification algorithm and detects a class label for the sample.