Patent Document ID: 8265955
Application ID: 13244762
Patent Flag: 1

Claim One:
1. A method for characterizing the probability of a clinical outcome of a subject, comprising: a. constructing one or more probability spaces with the aid of a computer processor that executes a program to construct said one or more probability spaces, wherein each probability space is defined by at least three discrete clinical outcomes, each discrete clinical outcome of said at least three discrete clinical outcomes is characterized by a statistical distribution of a set of biological marker(s), wherein the statistical distribution for a given set of biological marker(s) is different from all other statistical distributions for all other sets of biological markers characterizing each of the clinical outcomes within a given probability space, and wherein said given probability space is reflective of said at least three discrete clinical outcomes associated with a medical condition, medical procedure, therapy, clinical trial, drug discovery, or drug development; b. receiving, with the aid of a computer, subject data corresponding to the set of biological marker(s) for each discrete clinical outcome within the given probability space; c. calculating, with the aid of a computer processor that executes a program to determine the position of the subject data in the given probability space, the position of said subject data in said given probability space based on where said subject data falls within each statistical distribution of said set of biological marker(s) characterizing each said discrete clinical outcome; and d. repeating steps b) and c) at various time points to provide an output of a trajectory within said given probability space, wherein said trajectory is indicative of the likelihood of progression to one of said at least three discrete clinical outcomes.