Patent Document ID: 20090088418
Application ID: 12242389
Patent Flag: 0

Claim One:
1. A compound having the formula: wherein A is —N—; —CH—; or —C(C 1 -C 6 alkyl)-, optionally substituted with one or more groups selected from hydroxyl and halo; B is —NH—; —N(C 1 -C 6 alkyl)-, optionally substituted with one or more groups selected from hydroxyl and halo; —O—; or —S—; X is —O—; —NH—; —N(C 1 -C 6 alkyl)-, optionally substituted with one or more groups selected from hydroxyl and halo; —CH 2 —; or a bond; Y is a bond, —CH 2 —, —(CH 2 ) 2 —, —OCH 2 —, —C(O)—, —CH(OR 7 )—, —C(OR 7 ) 2 —, R 7 is independently —C 1 -C 6 alkyl, optionally substituted with one or more groups selected from hydroxyl and halo; R 1 and R 2 are each independently —H; —OH; —C 1 -C 6 alkoxy, optionally substituted with one or more groups selected from hydroxyl and halo; —C 1 -C 6 alkyl, optionally substituted with one or more groups selected from hydroxyl and halo; —C 1 -C 6 alkyl-(C 1 -C 6 alkoxy), optionally substituted with one or more groups selected from hydroxyl and halo; halo; —NO 2 ; —CN; —C(O)N(R 5 )R 6 ; —S(O) 2 R 5 ; —S(O) 2 N(R 5 )R 6 ; or wherein R 1 and R 2 are at adjacent carbons and together substituted with —O—CH 2 —O— to form a ring; and R 3 , R 4 , R 5 , and R 6 are each independently —H or —C 1 -C 6 alkyl, optionally substituted with one or more groups selected from hydroxyl and halo; with the proviso that when A is —N— or —CH—, B is —NH— or —N(C 1 -C 3 alkyl)-, X is —O—, Y is —CH 2 —, R 3 and R 4 are —H, and one of R 1 and R 2 is —H, then the other of R 1 and R 2 is not 7-alkoxy; or a pharmaceutically acceptable salt or solvate thereof.