Patent Document ID: 9984462
Application ID: 15705904
Patent Flag: 1

Claim One:
1. A method for distinguishing invasive cancerous pathology from non-invasive pathology, the method comprising: accessing a set of histology slices of a region of tissue demonstrating invasive cancerous pathology and non-invasive cancerous pathology, where a member of the set of histology slices has a thickness; generating a three dimensional (3D) histology reconstruction of the set of histology slices; accessing a set of 3D radiological images of the region of tissue, where a member of the set of 3D radiological images includes a texture feature or a shape feature; registering the 3D histology reconstruction with the set of 3D radiological images; generating a mapping of invasive cancerous pathology from the 3D histology reconstruction onto the set of 3D radiological images based, at least in part, on the registration; identifying, in a member of the set of 3D radiological images, a texture feature or a shape feature associated with invasive cancerous pathology based, at least in part, on the mapping; and training a classifier to distinguish invasive cancerous pathology from non-invasive cancerous pathology based, at least in part, on the mapping.