Patent Document ID: 7491543
Application ID: 11229327
Patent Flag: 1

Claim One:
1. A method of determining a subject's likelihood of longevity, likelihood of developing a cardiovascular related disease, likelihood of developing a metabolic syndrome, or likelihood of retaining cognitive function during aging, wherein the cardiovascular related disease is selected from the group consisting of hypertension, diabetes mellitus, myocardial infarction, stroke and transient ischemic attack, the method comprising comparing high density lipoprotein (HDL) particle size from the subject's plasma with high density lipoprotein (HDL) particle size from a control population, wherein an average size of the subject's high density lipoprotein (HDL) particles that is statistically significantly larger than an average size of high density lipoprotein (HDL) particles from the control population indicates that the subject has an increased likelihood of longevity, a decreased likelihood of developing a cardiovascular related disease, a decreased likelihood of developing a metabolic syndrome or an increased likelihood of retaining cognitive function during aging, or wherein an average size of the subject's high density lipoprotein (HDL) particles that is statistically significantly smaller than an average size of high density lipoprotein (HDL) particles from the control population indicates that the subject has an increased likelihood of developing a cardiovascular related disease or an increased likelihood of developing a metabolic syndrome.