Patent Document ID: 9924883
Application ID: 14317271
Patent Flag: 1

Claim One:
1. A method of recording neural signals in a subject, comprising: implanting a neural probe for recording the neural signals into neuronal tissue in the subject, wherein the neural probe comprises: a) a body comprising one or more electrodes exposed to the neuronal tissue, wherein the one or more electrodes are coupled to electrical conductors extending along the body which can be electrically coupled to a recording apparatus via one or more electrical leads; b) a parylene C insulating layer coating on the body and electrical conductors but not the one or more electrodes; and c) an L1 polypeptide coating conjugated to an exterior surface of the parylene C insulating layer and comprising from 0.1 ng/mm 2 to 10.0 ng/mm 2 L1 polypeptide; and recording the neural signals from the neuronal tissue after the neural probe has been implanted in the neuronal tissue for at least six months.