Patent Document ID: 20110245631
Application ID: 12751729
Patent Flag: 0

Claim One:
1. A method for predicting an onset of an acute hypotensive episode, the method comprising: reading heart rate data from a patient over a given time period; reading mean arterial pressure data from the patent over the given time period; conditioning the heart rate data and the mean arterial pressure data for use in determining an onset of an acute hypotensive episode; calculating a mean and standard deviation of random coefficients of a specific order linear neural model with a maximum likelihood estimator based on past read heart rate and mean arterial pressure data of the patient; generating predicted data points with mathematical models of a neural portion and an effector portion of a closed-loop system functioning of heart, vessels, and medullary cardiovascular centers with the calculated mean and standard deviation to determine the onset of the acute hypotensive episode; determining whether an acute hypotensive episode is occurring within the prediction window; and reporting the acute hypotensive episode and its onset time when detected.