Patent Document ID: 9568468
Application ID: 14212999
Patent Flag: 1

Claim One:
1. A method for identifying an agent that modulates motor or sensory neuron axon regeneration in an extended third instar (ETI) Drosophila larva, comprising: (i)contacting with a test agent an ETI Drosophila larva comprising a structural or functional disruption of one or more motor or sensory neuron axons; (ii) assessing motor or sensory neuron axon regeneration in the disrupted motor or sensory neuron axons by assessing one or more of growth of the disrupted motor or sensory neuron axons, neuromuscular junction formation, glial activation, motor or sensory neuron survival, or neuromuscular junction loss in the contacted ETI Drosophila larva, and (iii) identifying the test agent as an agent that modulates motor or sensory neuron axon regeneration if a result of the assessment of step (ii) in the presence of test agent differs from the result of the assessment in the absence of the test agent.