Patent Document ID: 9779206
Application ID: 13704655
Patent Flag: 1

Claim One:
1. A method for determining a quality control criterion for a target raw-Cq value of a target analyte obtained from quantitative polymerase chain reaction (PCR) measurements, the method comprising: determining, by a processor of a computing device, a target raw-Cq value from quantitative PCR measurements, the target raw-Cq value being representative of a concentration or activity of a target analyte from a first sample; determining by the processor, a reference raw-Cq value from quantitative PCR measurements, the reference raw-Cq value being representative of a concentration or activity of a reference analyte from at least one of (i) the first sample, and (ii) one or more other samples; calculating, by the processor, an unbounded delta-Cq value and respective confidence information based on a calculated difference between the target raw-Cq value and the reference raw-Cq value; calculating, by the processor, a bounded delta-Cq value and respective confidence information, wherein the bounded delta-Cq value is bounded by applying an upper bound, a lower bound, or both, the confidence information corresponding to the bounded delta-Cq value being used to determine a quality control criterion for the target raw-Cq value of the target analyte; and using the quality control criterion to perform a quality control action.