Patent Document ID: 9624307
Application ID: 14003963
Patent Flag: 1

Claim One:
1. A method of treating small ischemic injuries in a patient, comprising administering to the patient an effective amount of an inhibitor of Factor XII (FXII) to treat the small ischemic injuries, wherein the administering is performed before, during, and/or after a medical procedure in the patient comprising contact with at least one of: (a) the patient's heart, (b) at least one blood vessel in the patient chosen from: the aorta, the aortic arch, a carotid artery, a coronary artery, brachiocephalic artery, vertebrobasilar circulation, intracranial arteries, renal artery, a hepatic artery, a mesenteric artery, and/or a blood vessel of the arterial system cranial to the heart, and (c) a venous blood vessel in the patient if the patient has a known septal defect; wherein the medical procedure of (a), (b), and (c) comprises release of at least one microembolus in at least one of said heart and blood vessels of (a), (b), and (c) in the body.