Patent Document ID: 8271296
Application ID: 12729366
Patent Flag: 1

Claim One:
1. A computer-based method of improving operational effectiveness for a clinical trial in planning, wherein a computer-based calculating system performs the processes of: (i) inputting historical clinical trial operation data for a disease condition from different clinical trials, wherein said historical clinical trial operation data for each single trial of said different clinical trials comprise date site i closed for patient enrollment (Eti), date site i opened for patient enrollment (Sti), maximum number of sites (N) opened for enrollment in the duration of patient enrollment at the study level, date clinical trial closed for patient enrollment (Ets), and date clinical trial opened for patient enrollment (Sts); (ii) normalizing said data from different clinical trials; (iii) calculating Site Effectiveness Index (SEI) for said normalized data using said computer-based calculating system, wherein the SEI is defined as SEI = ∫ i = 1 N ⁢ ( Et i - St i ) ( Et s - St s ) × N ; and (iv) analyzing and identifying clinical trials based on said calculated SEIs, wherein clinical trial practices of the identified clinical trials could be used to improve operational effectiveness of a clinical trial in planning.