Patent Document ID: 10053733
Application ID: 14768578
Patent Flag: 1

Claim One:
1. A method of implanting an embryo in a female, the method comprising: (a) collecting oocytes with their cumulus and/or granulosa cells from the female; (b) measuring in the cumulus or granulosa cells from the oocytes exon levels of gene expression from the genes SASH1, CAMK1D and EFNB2; (c) making intra-patient based comparison of said exon level analysis of gene expression in the oocytes; (d) considering only p-values <0.05 in a paired t-test as significant for the biomarker genes SASH1, CAMK1D and EFNB2 in evaluating the competence of said oocytes to lead to childbirth, to implantation, to form a pre-implantation blastocyst or embryo, and/or to lead to fertilization; (e) fertilizing the oocyte having the highest competence as determined in (d); and (f) implanting the embryo in the female.