Patent Document ID: 10161004
Application ID: 14396827
Patent Flag: 1

Claim One:
1. A method for treating relapsing and remitting multiple sclerosis (RRMS) in a patient in need thereof at the clinical isolated syndrome (CIS) stage of RRMS, said method comprising: administering an immunomodulatory or immunosuppressive therapy to the CIS stage patient, wherein a sample taken from the patient before administration of the therapy is measured by next generation sequencing and exhibits: more than 6 read counts for hsa-miR-22-5p; more than 4.806 read counts for hsa-miR-125b-5p; more than 4.847 read counts for hsa-miR-629-5p; more than 418.792 read counts for hsa-miR-16-2-3p; more than 3.993 read counts for hsa-miR-100-5p; fewer than 7.194 read counts for hsa-miR-20a-5p; fewer than 580.403 read counts for hsa-miR-151a-3p; or fewer than 2.681 read counts for hsa-miR-7-1-3p.