Patent Document ID: 20130034907
Application ID: 13512453
Patent Flag: 0

Claim One:
1. A biological circuit chemotactic converter comprising: at least one input module (IM) n , at least one genetic toggle switch (TS) n , at least one logic module (LM) n , and at least two sensor modules (SM A and SM B ) n+1 , wherein the input module comprises an inducible promoter sequence (iP A ) operably linked to a repressor sequence encoding a repressor protein (R A ); wherein the genetic toggle switch (TS) n comprises a first repressible promoter sequence (rP 1 ) that drives expression of a second repressor sequence (R 2 ), and a second repressible promoter sequence (rP 2 ) that drives expression of a first repressor sequence (R 1 ), (rP 1 -R 2 and rP 2 -R 1 ); wherein the first and second repressor sequences encode first and second repressors proteins, and wherein the first repressible promoter sequence is inhibited by the first repressor protein and the second repressible promoter sequence is inhibited by the second repressor protein; wherein the logic module comprises a repressible promoter sequence (rP B ) operably linked to a repressor sequence (R B ); wherein each sensor module comprises a repressible promoter sequence (rP C and rP D ) operably linked to a nucleic acid sequence encoding a sensor molecule (sensor A and sensor B); and wherein n≧1.