Patent Document ID: 9060722
Application ID: 12796512
Patent Flag: 1

Claim One:
1. A method for generating a physiological estimate from input data, comprising the steps of: generating input data using a biomedical monitoring device comprising a data processor configured to run a dual estimation algorithm, wherein the input data comprises at least one of: a photoplethysmogram; and an electrocardiogram, processing said input data using said dual estimation algorithm, said dual estimation algorithm configured to use a dynamic state-space model to operate on the input data using both an iterative state estimator and an iterative model parameter estimator in generation of said physiological estimate, said dynamic state-space model configured to: mathematically represent probabilities of physiological processes that generate said physiological estimate and mathematically represent probabilities of physical processes that affect collection of the input data; said state estimator iteratively: operating on an initial input probability distribution function or a re-sampled probability distribution function using said dynamic state-space model to generate a second probability distribution function; applying Bayes rule to said second probability distribution function and the input data to form a third probability distribution function; and re-sampling said third probability distribution function as said re-sampled probability distribution function; generating said physiological estimate using said model parameter estimator, said physiological estimate comprising: a blood oxygen saturation; and a left-ventricular stroke volume; and warning of a hemorrhage using said physiological estimate.