Patent Document ID: 20050234238
Application ID: 10517416
Patent Flag: 0

Claim One:
1. A compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, wherein A is C or N; X is phenyl, pyridyl, pyrazinyl, thiaphenyl, quinolinyl, benzofuranyl, oxadiazolyl, diazolylpyridinyl, imidazolylpyridinyl, oxadiazolylphenyl, or benzodioxolyl; R 1 is hydrogen, halogen; or —C 1-6 alkyl, -cycloC 3-6 alkyl, or —C 1-6 alkenyl group, wherein any of the groups is optionally substituted with 1-6 substituents; wherein each substituent is independently halogen, —OH, —CN, or —SO 2 —C 1-6 alkyl; R 2 , and R 3 are each independently hydrogen, halogen, hydroxyl, —CN, —NO 2 ; or —C 1-6 alkyl, —C 2-6 alkenyl, —C 1-6 alkyl(C 2-6 alkenyl) 2 , —C 0-4 alkyl(C 3-6 cycloalkyl) 2 , —C 0-6 alkyl-N(C 0-6 alkyl) 2 , —C 0-4 alkyl-O—C 1-6 alkyl, —C 1-6 alkyl-phenyl, —C 0-6 alkyl-SO 2 —C 1-6 alkyl, —C 0-6 alkyl-C(O)—C 0-4 alkyl, —C 0-6 alkyl(O)—C 0-6 alkyl-phenyl, —C 0-6 alkyl-C(O)C 0-4 alkyl-O—C 0-6 alkyl, —C 0-6 alkyl-C(O)C 0-6 alkyl-O—C 0-6 alkyl-O—C 0-6 alkyl-C(O)C 0-6 alkyl, —C 2-6 alkenyl-C(O)—C 0-4 alkyl-O—C 0-6 alkyl, C 0-4 alkyl, C 3-6 cycloalkyl-C 0-6 alkyl-C(O)—C 0-6 alkyl, —C 0-4 alkyl-C 3-6 cycloalkyl-C 0-6 alkyl-C(O)C 0-6 alkyl-N(C 0-6 alkyl) 2 , —C 0-4 alkyl-C 3-6 cycloalkyl-C 0-6 alkyl-C(O)C 0-4 alkyl-O—C 0-6 alkyl, —C 2-6 alkenyl-C(O)—C 0-4 alkyl-N(C 0-6 alkyl)pyridyl, —C 0-6 alkyl-C(O)C 0-4 alkyl-N(C 0-4 alkyl) 2 , —C 0-6 alkyl-C(O)C 0-4 alkyl-N(C 0-4 alkyl)—C 3-6 cycloalkyl —C 2-6 alkenyl-C(O)—C 0-4 alkyl-N(C 0-4 alkyl)—C 3-6 cycloalkyl, —SO 2 —C 0-6 alkyl-phenyl, —SO 2 —C 0-6 alkyl-C 0-6 alkyl-phenyl)(C 0-6 alkyl-phenyl), —C 0-4 alkyl-SO 2 —C 0-4 alkyl-C 3-6 cycloalkyl-C 0-4 alkyl-C(O)—C 0-4 alkyl-O—C 0-4 alkyl, —S(O)—C 0-6 alkyl, —P(O)(O)—C 0-4 alkyl)(O)—C 0-4 alkyl), —C 2-6 alkenyl-C(O)C 0-4 alkyl-N(C 0-4 alkyl)pyridyl, —S—C 1-6 alkyl, —C 0-6 alkyl-N(C 0-6 alkyl)—C(O)—C 0-6 alkyl, —C 0-6 alkyl-N(C 0-6 alkyl)—C(O)N(C 0-6 alkyl) 2 , —C 0-4 alkyl-S—C 1-4 alkyl-oxadiazolyl(C 0-4 alkyl), —C 0-4 alkyl(O)—C 0-4 alkyl-phenyl, —C 0-4 alkyl-O—C 0-4 alkyl-phenyl, —C 0-4 alkyl-C 3-6 cycloalkyl-C 0-4 alkyl-tetrazolyl, —SO 2 —N(C 0-4 alkyl) 2 , —C 0-4 alkyl-S—C 0-4 alkyl-thiadiazolyl(C 0-4 alkyl), —C 0-4 alkyl-S—C 0-4 alkyl-diazolyl(C 0-4 alkyl), —C 0-4 alkyl-S—C 1-4 alkyl-Si(C 0-4 alkyl) 3 , —C 0-4 alkyl-S—C 0-4 alkyl-phenyl(C 0-4 alkyl), —C 0-4 alkyl-S—C 0-4 alkyl-C(O)—C 0-4 alkyl-O—C 0-4 alkyl, or —C 0-4 alkyl-S— 0-4 alkyl-C 3-6 cycloalkyl-C 0-4 alkyl-C(O)C 0-4 alkyl-O—C 0-4 alkyl, wherein any alkyl, cycloalkyl, alkenyl, phenyl, or pyridyl are each optionally substituted with 1-9 independently halogen, hydroxyl, —C 0-4 alkyl-O—C 1-6 alkyl, or —C 0-4 alkyl-S—C 1-6 alkyl; optionally, R 2 forms ═O with an adjoining bond; R 4 is hydrogen, or halogen; and any ring nitrogen optionally forms N-oxide or N-chloride.