Patent Document ID: 9760676
Application ID: 15098248
Patent Flag: 1

Claim One:
1. A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: for each biological sample of an aggregate set of samples associated with a population of subjects: determining a microorganism nucleic acid sequence, comprising: identifying primers for nucleic acid sequences associated with the endocrine system condition; fragmenting nucleic acid material from the biological sample; and amplifying the fragmented nucleic acid material using the identified primers; and determining an alignment of the microorganism nucleic acid sequence to a reference nucleic acid sequence associated with the endocrine system condition; generating a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects based upon the alignment; receiving a supplementary dataset, associated with at least a subset of the population of subjects, wherein the supplementary dataset is informative of characteristics associated with the endocrine system condition; generating a characterization of the endocrine system condition based upon the supplementary dataset and features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model for improving a state of the endocrine system condition; and at an output device associated with the subject, providing a therapy to the subject with the endocrine system condition based upon the characterization and the therapy model, wherein the therapy modulates microbiome composition of the subject towards an equilibrium state.