Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD
NCT Number: NCT06510686
Acronym: COPD
Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Copd
Interventions: OTHER: İnspiratory muscle training|OTHER: Core training
Sponsor: Mustafa Ertuğrul Yaşa
Sex: ALL
Age: ADULT, OLDER_ADULT
Enrollment: 38
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2024-08-01
Completion Date: 2025-09-01

Summary:
In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the respiratory workload. This results in impaired coordination of muscle groups, leading to muscle dysfunction. Respiratory muscle dysfunction is a significant determinant of life expectancy in COPD. Additionally, respiratory muscles unable to cope with increased workloads lead to impaired respiratory functions and reduced exercise capacity.

It is widely accepted that appropriate training of respiratory muscles can increase their strength, endurance, and their close relationship with lung volume capacities. Besides their role in respiration, respiratory muscles also contribute to postural function and core stabilization. Studies on respiratory muscle training in COPD have primarily focused on inspiratory muscle strength training, neglecting the core stabilization function of respiratory muscles. However, optimal gains in a muscle can only be achieved with training tailored to its functional characteristics. Therefore, a comprehensive training program should be developed considering the multifunctional nature of respiratory muscles. Studies published in healthy individuals and different patient populations demonstrate that core training can improve lung functions. The aim of this study is to compare the effects of inspiratory muscle training and core stabilization training on diaphragm activation, inspiratory muscle strength, functional capacity, respiratory functions, physical activity, and quality of life in individuals with COPD.

Primary Outcome Measures: Inspiratory Muscle Strength, Maximal Inspiratory Pressure (MIP) (cmH2O),, 8 weeks|Inspiratory Muscle Activation, surface EMG (TLC from FRC (TLC maneuver)(cmH2O), 8 weeks|Respiratory function tests FEV1, Spirometry, FEV1 (lt), 8 weeks|Respiratory function tests FVC, Spirometry, FVC (lt), 8 weeks|Respiratory function tests PEF, Spirometry, PEF (lt/sn), 8 weeks|Respiratory function tests FEV1/FVC, Spirometry, FEV1/FVC %, 8 weeks|Respiratory function MVV, Spirometry, MVV(L/min), 8 weeks|Functional capacity, Six Minute Walking Test (6MVT) (m), 8 weeks|Symptoms, MMRC Dyspnea Scale (Scores range from 0 to 4), 8 weeks
Secondary Outcome Measures: Physical activity,, IPAQ (MET/minute), 8 week|Quality of life Tests, SGRQ (Scores range from 0 to 100), 8 week|Core Strength, 1 minute sit to stand ( how many times sit and stand during 1 minute), 8 week|Core Strength flexion, Mcgill Endurance Tests For Trunk Flexion (sec), 8 week|Core Strength extension, Mcgill Endurance Tests For Trunk Extension (sec), 8 week|Core Strength side bridge, Mcgill Endurance Tests For Side Bridge (sec), 8 week