Respiratory Training in Individuals With Ankylosing Spondylitis
NCT Number: NCT06490796
Status: RECRUITING
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Ankylosing Spondylitis|Exercise Training|Diaphragm|Mobility
Interventions: BEHAVIORAL: Expanded diaphragm exercise|BEHAVIORAL: Standard diaphragm exercise
Sponsor: Izmir University of Economics
Sex: ALL
Age: ADULT
Enrollment: 50
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Start Date: 2024-06-06
Completion Date: 2025-03-01
Locations: Izmir University of Economics, Izmir, 35330, Turkey

Summary:
This study was designed to investigate and compare the effects of standard diaphragmatic breathing and physiotherapy exercises versus 360-degree expandable diaphragmatic breathing and physiotherapy exercises on respiratory functions, respiratory muscle strength, clinical course of the disease (such as thoracic mobility, flexibility), and functional status in individuals with Ankylosing Spondylitis (AS).

Primary Outcome Measures: Spinal movements and spinal mobility, The Bath Ankylosing Spondylitis Metrology Index (BASMI) will be used to measure clinical differences in spinal movements and spinal mobility. BASMI includes five measurements: cervical rotation, tragus-to-wall distance, lateral lumbar flexion, anterior lumbar flexion, and intermalleolar distance. A lower score on the BASMI indicates better spinal mobility (15)., From enrollment to the end of treatment at 6 weeks
Secondary Outcome Measures: Functional status, The functional status of individuals with ankylosing spondylitis will be assessed using Bath Ankylosing Spondylitis Functional Index (BASFI,0-10 cm)., From enrollment to the end of treatment at 6 weeks|Respiratory muscle strength, Respiratory muscle strength will be measured using a portable device capable of electronically measuring intraoral pressure (RP Check, MD Diagnostics Ltd., Maidstone, UK). Using the non-invasive method of intraoral pressure measurement, maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) will be recorded., From enrollment to the end of treatment at 6 weeks|Expiratory Forced Vital Capacity (FVC), the maximum amount of air that can forcibly be blown out after full inspiration, From enrollment to the end of treatment at 6 weeks|Forced Expiratory Volume in one second (FEV1), FEV1 is the volume of air that can forcibly be blown out in first 1 second after full inspiration., From enrollment to the end of treatment at 6 weeks|Forced Expiratory Flow at 25-75% of FVC (FEF25-75%), Mean of forced expiratory flow over the middle half of the forced vital capacity., From enrollment to the end of treatment at 6 weeks|FEV1/FVC ratio (FEV1%), Ratio of forced expiratory volume in one second to forced vital capacity., From enrollment to the end of treatment at 6 weeks|Disease activity, Disease activity will be assessed using Ankylosing Spondylitis Disease Activity Index' in (BASDAI) clinical diagnosis and evaluation of disease activity. This index is used to define the activity, progression, and prognosis of the disease. It is interpreted on a score ranging from 0-10. An increase in the score indicates an increase in disease activity., From enrollment to the end of treatment at 6 weeks