Risk of Sudden Cardiac Death in UN Athletes
NCT Number: NCT06518252
Acronym: Suddendeath
Status: RECRUITING
Study Type: OBSERVATIONAL
Conditions: Death, Sudden, Cardiac|Electrocardiogram QT Prolonged|Athlete Heart|Athletic Injuries
Sponsor: Universidad Nacional de Colombia
Sex: ALL
Age: ADULT
Enrollment: 250
Study Design: Observational Model: |Time Perspective: p
Start Date: 2023-11-24
Completion Date: 2025-06-25
Locations: Juan Murillo-Coca, Bogotá, Cundinamarca, 110821, Colombia

Summary:
The detection of sudden cardiac death risk in athletes is a topic of great relevance in the field of sports physiotherapy and physical activity. High-performance sports practice involves anatomical and physiological changes that can modify the mechanical and electrical properties of the heart, increasing the risk of potentially fatal cardiac events. Therefore, it is essential to implement early detection strategies to identify at-risk athletes and prevent tragedies during sports practice.

Methodology: This study focuses on the prevalence of sudden cardiac death risk, using a 12-lead electrocardiogram as the primary detection tool. This examination will allow for the evaluation of the heart's electrical activity and the detection of potential anomalies that could predispose athletes to adverse cardiac events during sports practice. In addition to the electrocardiogram, cardiovascular screening questionnaires will be administered to collect information on personal and family health histories, as well as other relevant risk factors. In conjunction with the project's researchers, the sports medical team of the Universidad Nacional de Colombia will be responsible for conducting the evaluations, ensuring the precision and reliability of the obtained results. A detailed analysis of the collected data will be performed using statistical tools to identify possible correlations between the evaluated risk factors and the presence of sudden cardiac death risk in athletes. Logistic regression models will be employed to determine the strength of association between the studied variables and cardiovascular risk in this specific population.

Expected Results: It is anticipated that implementing pre-participation evaluations, including the electrocardiogram and cardiovascular screening questionnaires, will enable the identification of athletes at higher risk of sudden cardiac death. These results will allow for the establishment of individualized risk profiles and the design of personalized prevention strategies for each athlete. Additionally, it is expected that the findings of this study will contribute to the development of early detection protocols for sudden cardiac death risk in athletes, which can be effectively implemented in sports settings. The information generated from this study will provide a solid foundation for clinical decision-making and the implementation of preventive measures to benefit the health and well-being of high-performance athletes.

Primary Outcome Measures: Sudden death due to ventricular hypertrophy., People whose electrocardiographic findings are outside the normal parameters and who present left or right ventricular hypertrophy with isolated QRS voltage to the left side (SV1 þ RV5 or RV6 \>3.5 mV) or right ventricular hypertrophy (RV1 þ SV5 or SV6 \> 1.1mV), 8 months|Sudden death due right bundle branch block, People whose electrocardiographic findings are outside normal parameters and presenting rSR0 in V1 and qRS pattern in V6 with QRS duration \<120 ms., 8 months|Sudden death due to repolarization pattern, People whose electrocardiographic findings are outside the parameters of normality/ST elevation with J point elevation, ST segment elevation, J waves or dragged terminal QRS in the inferior and/or lateral leads, 8 months|Sudden death due to ST elevation, ST elevation followed by T wave inversion in V1-V4 in black athletes: J-point elevation and convex ("domed") ST segment elevation followed by T wave inversion in leads V1-V4 in athletes black, 8 months
Secondary Outcome Measures: Sporting modality, Human behavior characterized by a playful and competitive attitude of verification or challenge expressed through physical and mental exercise, within established disciplines and rules. Includes different types of sports according to specific rules and game norms., 8 months|Training volume, Training Duration is a quantitative variable that measures the total time spent in an exercise or physical training session. It is expressed in units of time and is understood as the number of minutes of training per week., 8 months|Borg scale modified., Exercise intensity during a training session, measured by coach and athlete self-report using the modified Borg scale with a score from 0 to 10. Scale Description: 0: No effort, 0.5: Very, very light, 1 : Very light, 2: Light, 3: Moderate, 4: Somewhat heavy, 5: Heavy, 6-7: Very heavy, 8-10: Very, very heavy, 8 months|Weekly Training Frequency, Number of training sessions that a person performs in a week, I understand a training session as the activity planned and carried out for more than 30 minutes. The total number of exercise sessions performed in a week will be taken., 8 months
Other Outcome Measures: Age, Time of life that a person has lived since birth. It will include individuals whose ages range from 18 to 35 years old., 8 months|Sex, Organic condition that defines individuals as male or female. Individuals will not be discriminated against based on gender., 8 months