Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section
NCT Number: NCT06514040
Status: RECRUITING
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Precedex|DRUG: Sumatriptan 25 mg
Sponsor: Fayoum University Hospital
Sex: FEMALE
Age: ADULT
Enrollment: 48
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Start Date: 2023-11-27
Completion Date: 2024-09
Locations: Fayoum University hospital, Madīnat Al Fayyūm, Faiyum Governorate, Egypt

Summary:
comparison between oral sumatriptan and Nebulized Dexmedetomidine in Post Dural Puncture Headache in Cesarean Section

Primary Outcome Measures: visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, First 48 hours
Secondary Outcome Measures: visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 6 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 12 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 18 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 24 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 30 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 36 hours.|visual analogue scale, VAS Score from 0 to 10 where score 0 is no headache and 10 is the worst one, 42 hours.|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 6 hours|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 12 hours|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 18 hours|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 24 hours|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 30 hours|Lybecker score, Mild

Mild:Daily activities slightly restricted. Patient is not bedridden

No associated symptoms

Moderate:Daily activities significantly restricted and most of the day patient is bedridden with or without associated symptoms

Severe:Daily activities completely restricted, patient is bedridden all the day and always with associated symptoms, 36 hours