Dexamethasone With Ropivacaine for PENG Block in Total Hip Arthroplasty
NCT Number: NCT06470334
Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL
Phases: PHASE4
Conditions: Hip Osteoarthritis|Hip Pain Chronic|Hip Arthritis
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine+Dexamethasone
Sponsor: Poznan University of Medical Sciences
Sex: ALL
Age: OLDER_ADULT
Enrollment: 60
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Start Date: 2024-07-01
Completion Date: 2025-09-30
Locations: Poznan University of Medical Sciences, Poznan, Poznań, 61-701, Poland

Summary:
Does adding Dexamethasone to the Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty reduce the dose of ropivacaine?

Primary Outcome Measures: Time to first rescue opioid analgesia, Time after surgery when the patient needs opiate for the first time, 48 hours after surgery
Secondary Outcome Measures: Total Opioid Consumption, Total opiate consumption after surgery, 48 hours after surgery|Numerical Rating Scale [range 0:10], Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt), 4 hours after surgery|Numerical Rating Scale [range 0:10], Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt), 8 hours after surgery|Numerical Rating Scale [range 0:10], Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt), 12 hours after surgery|Numerical Rating Scale [range 0:10], Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt), 24 hours after surgery|Numerical Rating Scale [range 0:10], Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt), 48 hours after surgery|Quadriceps muscle strength assessed using medical research council scale [range 0:5], Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating, 4 hours after surgery|Quadriceps muscle strength assessed using medical research council scale [range 0:5], Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating, 8 hours after surgery|Quadriceps muscle strength assessed using medical research council scale [range 0:5], Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating, 12 hours after surgery|Quadriceps muscle strength assessed using medical research council scale [range 0:5], Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating, 24 hours after surgery|Quadriceps muscle strength assessed using medical research council scale [range 0:5], Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating, 48 hours after surgery|NLR, Neutrophil-to-lymphocyte ratio, 24 hours after surgery|NLR, Neutrophil-to-lymphocyte ratio, 48 hours after surgery|PLR, platelet-to-lymphocyte ratio, 24 hours after surgery|PLR, platelet-to-lymphocyte ratio, 48 hours after surgery|glucose, blood glucose level, 24 hours after surgery|glucose, blood glucose level, 48 hours after surgery