Assessment of Facial Symmetry After Facial Reconstruction Using Three-dimensional Stereophotogrammetry
NCT Number: NCT06534970
Acronym: SymFACE
Status: NOT_YET_RECRUITING
Study Type: OBSERVATIONAL
Conditions: Facial Reconstruction
Interventions: DEVICE: Three-dimensional stereophotogrammetry|OTHER: Questionnaires
Sponsor: Assistance Publique Hopitaux De Marseille
Collaborators: Fondation des Gueules Cassées
Sex: ALL
Age: ADULT, OLDER_ADULT
Enrollment: 50
Study Design: Observational Model: |Time Perspective: p
Start Date: 2024-09
Completion Date: 2026-09

Summary:
Facial reconstruction follows removal of a malignant or benign tumor of the oral cavity or face, complex facial trauma, or resection of osteonecrosis of the jaws. It's a challenge that aims to restore not only the functions of the face, but also its aesthetics, which is just as crucial. A poor aesthetic result after facial reconstruction has a serious impact on patients' lives. To develop more personalized surgery, and to anticipate and correct poor results in the future, it is essential to better understand the factors associated with poor aesthetic results in this type of surgery, as well as their impact on the patient's life.

This means correctly assessing the aesthetic outcome of this surgery. Today, however, aesthetic evaluation criteria remain inadequate. A number of criteria are involved in facial attractiveness, and facial symmetry is a key factor. It is generally accepted that severe facial asymmetries considerably diminish facial attractiveness. Currently, aesthetic evaluation criteria (particularly symmetry) are based primarily on the subjective perception of the surgeon or patient. However, there is a need to be able to measure facial symmetry objectively.

Methods for assessing symmetry rely on the placement of anatomical landmarks and the calculation of Euclidean distance, which involves locating homologous landmarks on each side of the face and comparing the length ratios of all possible lines connecting the landmarks on each side. However, these techniques are based on measurements often on two-dimensional (2D) photographs and do not take into account the three-dimensional nature of the face. Methods for three-dimensional analysis of facial symmetry have been developed based on three-dimensional CT reconstructions. However, this technique implies the use of an irradiating imaging technique, not systematically indicated at a distance from surgery.

Our study aims to validate a method for analyzing facial symmetry using three-dimensional stereophotogrammetry, to identify risk factors for facial asymmetry in patients who have undergone facial reconstruction, and to assess the impact of facial asymmetry on patients' quality of life.

Primary Outcome Measures: Correlation coefficient between root mean square deviation (RMSE) score and surgeon's assessment score, Day 1
Secondary Outcome Measures: Intraclass Correlation Coefficient to assess intra-operator reproducibility, Day 1|Intraclass Correlation Coefficient to assess inter-operator reproducibility, Day 1|Demographic factors associated with objective facial asymmetry one year after facial reconstruction surgery, Day 1|Clinical factors associated with objective facial asymmetry one year after facial reconstruction surgery, Day 1|Therapeutic factors associated with objective facial asymmetry one year after facial reconstruction surgery, Day 1|Relationship between objective measurement of facial asymmetry and the patient's subjective assessment of perception (satisfaction and body image), The patient perception score is assessed by a scale constructed by the investigative team., Day 1|Relationship between objective measurement of facial asymmetry and the patient's quality of life, The patient quality of life score is assessed by the French-validated SF-36 quality of life scale for general health inquiry" (36 items)., Day 1|Relationship between objective measurement of facial asymmetry and patient self-esteem, The patient self-esteem score is assessed by the French-validated Rosenberg self-esteem scale (10 items)., Day 1