How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion
NCT Number: NCT06494293
Acronym: TRAP
Status: NOT_YET_RECRUITING
Study Type: OBSERVATIONAL
Conditions: Trauma Injury
Interventions: OTHER: Data Collection
Sponsor: Hôpital NOVO
Collaborators: Direction Centrale du Service de Santé des Armées
Sex: ALL
Age: ADULT, OLDER_ADULT
Enrollment: 200
Study Design: Observational Model: |Time Perspective: p
Start Date: 2024-09
Completion Date: 2024-10
Locations: Resuscitation Services (SMUR) Ballanger - Centre Hospitalier Intercommunal Robert Ballanger, Aulnay-sous-Bois, 93600, France|Resuscitation Services (SAMU/SMUR) - Hôpital NOVO -Beaumont/Oise Site, Beaumont-sur-Oise, 95260, France|Resuscitation Services (SAMU/SMUR) - Hôpital NOVO -Pontoise Site, Pontoise, 95300, France|Resuscitation Services (SMUR) Delafontaine - Centre Hospitalier de Saint-Denis, Saint-Denis, 93000, France

Summary:
The aim of the study is to measure the number of patients being cared for by a medical team for major trauma who could benefit from a transfusion labile blood products and thus provide a scientific argument in favour of supplying labile blood products to pre-hospital

Primary Outcome Measures: Measurement of the proportion of patients being cared for a medical team for major trauma who could have benefited from a pre-hospital transfusion, The main analysis criterion will be the presence, during pre-hospital management, of a massive and immediate blood transfusion criterion measured by the ABC (Assessment of Blood Consumption) score between the arrival of the MICU and 10 minutes before arrival at the hospital.

This score is used to predict the need for massive transfusion, defined in particular as the administration of 4 labile blood products within the first hour of hospital care.

This score will be calculated retrospectively on the basis of data collected from the medical record at the time the patient is taken into medical care, and then every 10 minutes during the course of the care until 10 minutes after arrival at hospital.

An ABC score greater than or equal to 2 indicates a probability of massive transfusion greater than 75%. We will consider a score \>= 2 as "probably requiring a pre-hospital transfusion"., At the end of the study, an average of 4 month
Secondary Outcome Measures: Evaluation of the concordance between the number of patients who received a transfusion during their pre-hospital care and the ABC (Assessment of Blood Consumption) score, The concordance will be assessed by the presence of at least one transfusion, whatever the volume between the work-up and arrival at hospital., At the end of the study, an average of 4 month|Assessment of patient mortality on arrival at the resuscitation/recovery centre, Mortality will be assessed by the number of patients alive on arrival of the MICU and dead on arrival at hospital., At the end of the study, an average of 4 month|Assessment of patients care time, Care time will be determined by the time between the arrival of the medical team and arrival at the hospital., At the end of the study, an average of 4 month|Assessment of the number of patients who could have benefited of a REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta), This number will be assessed as follow : number of patients potentially eligible for placement of a REBOA in terms of the presence of abdominal or pelvic bleeding on ultrasound, a PAS \> 90 mmHg despite 3 mg/h NAD (noradrenaline) and the absence of thoracic trauma or Supra Aortic Trunks (SATs)., At the end of the study, an average of 4 month