Relative Energy Deficiency in Sport and Dance
NCT Number: NCT06480682
Status: NOT_YET_RECRUITING
Study Type: OBSERVATIONAL
Conditions: Relative Energy Deficiency in Sport|Bone Stress Reaction
Interventions: RADIATION: Dual x-ray scan|DIAGNOSTIC_TEST: Blood screen|OTHER: Questionnaires|OTHER: Anthropometric measurements|PROCEDURE: Resting Metabolic rate|OTHER: Energy expenditure
Sponsor: University of Wolverhampton
Sex: ALL
Age: CHILD, ADULT
Enrollment: 200
Study Design: Observational Model: |Time Perspective: p
Start Date: 2024-09-10
Completion Date: 2029-07-30
Locations: University of Wolverhampton, Walsall, West Midlands, WS1 3BD, United Kingdom

Summary:
The International Olympic Committee recently published its consensus statement on relative energy deficiency syndrome (REDs) in sport which was followed by a similar version for dance by clinicians and researchers in dance. REDs is a complex multisystem syndrome with low energy availability as its foundation. Dancers and gymnasts, particularly in ballet, have long been reported to have body weight issues with an increase prevalence of eating disorders which has been associated with early onset osteoporosis. Combat sports have a similar issue, with athletes needing to "make weight" to compete in their ideal weight category that has lead to similar eating disorder and associated issues to dance. Currently there are no data on REDs prevalence in dance, gymnastics or combat sports and therefore understanding the underlying prevalence of REDs in both these populations will provide important information for both clinicians and coaches to help develop a safe and healthy environment for their dancers and athletes to compete/perform and to be able to retire from sport/dance without an increased risk of osteoporosis. In a few sports and dance genres, some participants might be more prone to a negative health effect referred to as relative energy deficiency syndrome (REDs). This is an energy deficiency relative to the balance between dietary energy intake and energy availability required to support homeostasis, health and activities of daily living, growth and sporting activities that can result in multiple systems being affected including decreases in bone health, energy metabolism, reproductive function, musculoskeletal health, immunity, glycogen synthesis and cardiovascular and haematological health. The purpose of this study is to examine the prevalence of REDs in specific sports (combat sports and gymnastics) and dance genres (ballet and musical theatre). Voluntary participants will be tested three times a year over a 5-year period. This will include an annual dual-energy x-ray absorptiometry and blood tests plus resting energy expenditure and questionnaires three times a year.

Primary Outcome Measures: Relative energy deficiency (REDs), Prevalence of REDs in cohorts by diagnosis by elimination by medical team., Throughout study; an average of 3 times a year
Secondary Outcome Measures: Bone stress injuries, Reported bone stress injuries by the inhouse medical teams, Number of participants with bone stress injuries. Throughout study an average of 3 times a year|Primary Amenorrhea (females), Loss of menses for at least 6 months, Number of participants with primary and secondary amenorrhea. Throughout study an average of 3 times a year|Resting Metabolic rate, Actual resting metabolic rate/estimated metabolic rate below 0.9, Throughout study; an average of 3 times a year|Monitoring of all blood markers for below normal values (red flags), Blood markers: full blood count, ferritin, B12, folate, erythrocyte sedimentation rate (ESR), renal function, liver function, thyroid stimulating hormone (TSH), Free thyroxine (T4), luteinizing hormone (LH), oestradiol, testosterone, follicle-stimulating hormone (FSH), coeliac screen, vitamin D (25(OH)D), Leptin and Ghrelin, Throughout study; an average of 3 times a year