Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
NCT Number: NCT06469073
Status: RECRUITING
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Anesthesia
Interventions: PROCEDURE: Transversus thoracic muscle plane block or Erector spinal plane block
Sponsor: Le Yu
Sex: ALL
Age: ADULT, OLDER_ADULT
Enrollment: 60
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Start Date: 2024-06-25
Completion Date: 2024-09-01
Locations: Shanghai East Hospital of Tongji University, Shanghai, Shanghai, 200120, China

Summary:
Sternum midline incision can offer better view under open-heart surgery and bigger operating space, and therefore it has been widely used in most cardiac surgery. If an event of urgency occurs, it takes on a more important role than infrasternal small incision. However, sternum midline incision may cause serious pain and aggravates stress response, and therefore patients are often reluctant to cooperate to cough which exerts adverse effect on postoperative rehabilitation, and even causes serious complications such as pulmonary inflammation, myocardial infarction and heart failure. Thus, the relief of pain and better perioperative analgesia are very important for these patients. Transversus thoracic muscle plane(TTMP) block and erector spinal muscle plane(ESP) block are used in open heart surgery currently, and they can provide good analgesia. This study aimed to investigate the hemodynamic stability, total amount of analgesic use, perioperative pain, stress response, postoperative complication and recovery in patients receiving TMP and ESP.

Primary Outcome Measures: Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, entering the operating room (T0)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, intubation (T1)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, skin incision (T2)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, breast opening (T3)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, sternal retractor placement (T4)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, pericardium incision (T5)|Mean arterial pressure, an average blood pressure in an individual during a single cardiac cycle, steel wire pulling (T6)|Heart beats, the number of times each minute that heart beats, entering the operating room (T0)|Heart beats, the number of times each minute that heart beats, intubation (T1)|Heart beats, the number of times each minute that heart beats, skin incision (T2)|Heart beats, the number of times each minute that heart beats, breast opening (T3)|Heart beats, the number of times each minute that heart beats, sternal retractor placement (T4)|Heart beats, the number of times each minute that heart beats, pericardium incision (T5)|Heart beats, the number of times each minute that heart beats, steel wire pulling (T6)