Geriatric Assessment at Discharge From the Intensive Care Unit in Patients Aged 75 Years and Older: a Feasibility Study
NCT Number: NCT06513130
Acronym: PreGEDI
Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Critical Illness|Geriatric Assessment|Older People|Frailty
Interventions: OTHER: Geriatric assessment in the 7 days following ICU discharge.|OTHER: No geriatric assessment in the 7 days following ICU discharge.
Sponsor: University Hospital, Strasbourg, France
Sex: ALL
Age: OLDER_ADULT
Enrollment: 70
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Start Date: 2024-08-01
Completion Date: 2026-10-01
Locations: Service de Médecine Intensive - Réanimation / CHU Strasbourg - France, Strasbourg, 67091, France

Summary:
The number of patients aged over 75 continues to grow, and, according to INSEE, will represent almost 10% of the French population in 2021, an increase of 2.4 points since 2000. This demographic change is also observed in the intensive care units, where admitted patients aged over 80 represent now up to 10-20% of critical care admissions, depending on the facility.

The admission of these patients remains controversial, with questions about the benefit to elderly patients, both in terms of in-hospital and distant survival, as well as induced morbidity or subsequent quality of life: functional status is impaired in up to two-thirds of survivors.

The challenge of identifying the patients most able to withstand a stay is a major one. Indeed, a stay in intensive care represents a major stress for the organism, due to the acute condition associated with one or more organ failure(s). Bed rest, immobilization and the use of drugs are responsible for formidable complications in the elderly: muscle-wasting, loss of adaptation to physical effort, loss of autonomy, delirium and agitation, all of which have their own long-term impact.

While many studies have looked at the prognostic factors on admission of these patients, and the selection of the patient with the greatest probability of surviving the intensive care unit (ICU), improving the outcome of patients who survive to the ICU stay remains a little-investigated subject. However, the impact of physical and psychological disturbances induced by these patients' stay in intensive care is major, and their detection and management could be elements of interest in improving the care of this population. However, the feasibility of carrying out such an assessment immediately after an ICU stay has yet to be evaluated. The aim of this study would be to evaluate the feasibility of a geriatric assessment at the end of the ICU stay (or within 7 days of discharge) and at 6 months. This study is a prospective, randomized, single-center, open-label interventional study.

Primary Outcome Measures: Rate of patients for whom a geriatric assessment is carried out between the end of their stay in intensive care and 7 days after discharge., At 6 Month after ICU discharge
Secondary Outcome Measures: Rate of patients for whom consultation at M6 is carried out., At 6 Month after ICU discharge|Frailty, assessed using the Clinical Frailty Scale, At 6 Month after ICU discharge|Total hospital length of stay, At 6 Month after ICU discharge|Number of hospitalization, At 6 Month after ICU discharge|Regular treatment modifications, collection of current treatments on admission to intensive care, on discharge from intensive care and hospitalization, and at M6 (prescription), At 6 Month after ICU discharge|Modification of place of living, location (single-family dwelling, retirement home, etc.), At 6 Month after ICU discharge|Evolution of the quality of life assessed by the SF-36 questionnary, For the interventional arm, At 6 Month after ICU discharge|Evolution of the psychological behaviours through the mini Geriatric depression score evolution and the Covi test evolution for the anxiety component., For the interventional arm, At 6 Month after ICU discharge|Evolution of the psychological behaviours through the Covi test evolution for the anxiety component., For the interventional arm, At 6 Month after ICU discharge|Evolution of the Katz-ADL score between initial assessment and month 6, For the interventional arm For the control arm,, At 6 Month after ICU discharge|Evolution of the IADL score between initial assessment and month 6, For the interventional arm For the control arm,, At 6 Month after ICU discharge|Evolution of the locomotor abilities, At 6 Month after ICU discharge|Evolution of cognition evaluation: mini Mental State Examination, At 6 Month after ICU discharge|At M6: main organ function assessment, At 6 Month after ICU discharge