Regulation of HIIT Combined With IET on Vascular Function in Young Women With Normal Weight Obesity
NCT Number: NCT06556875
Status: COMPLETED
Study Type: INTERVENTIONAL
Phases: NA
Conditions: Normal Weight Obesity
Interventions: BEHAVIORAL: HIIT|BEHAVIORAL: HIIT combined IET
Sponsor: Beijing Sport University
Sex: FEMALE
Age: ADULT
Enrollment: 45
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Start Date: 2023-02-23
Completion Date: 2023-12-30
Locations: School of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, China

Summary:
Comparison of the effects of combined IET with HIIT and HIIT on vascular function in young NWO women.

Primary Outcome Measures: Intima-Media Thickness (IMT), The subjects were required to sit still for 5～10 minutes before the test, and the carotid artery structural and functional parameters were recorded using a GE vivid 7 colour ultrasound instrument from the United States as follows: the subjects were required to lie in the supine position, and the probe was used to sweep longitudinally along the outer edge of the sternocleidomastoid muscle, and the maximal Intima-media thickness (IMT) was measured. Changes in Intima media thickness before and after intervention., 8 weeks|Flow-Mediated Dilation (FMD), Vascular endothelial function was measured with a Japanese-made UNEX EF vascular endothelial function tester. Pressure was applied on top of the resting blood pressure and the ischaemic process was performed for 5 min. At the end of the ischaemic process, the pressure band was removed and flow-mediated dilation (FMD) of the brachial artery was calculated. Changes in Flow-mediated dilation before and after Intervention, 8 weeks
Secondary Outcome Measures: Body Composition Indicators, Body composition indicators analysis was assessed using DXA. Body composition indicators include: fat mass(kg), lean body mass(kg), percentage of body fat(%)., 8 weeks|Body Mass Index (BMI), Is calculated from the formula, Weight (kg) / Height2 (m2), whose unit is kg/m2. It is a rough indicator of total body fat. Changes in Body mass index before and after Intervention., 8 weeks|Blood Pressure (BP), Quiet blood pressure: Systolic and diastolic blood pressures are measured using a standard mercury sphygmomanometer. Changes in blood pressure before and after intervention, including systolic blood pressure, diastolic blood pressure, and pulse pressure difference., 8 weeks|Pulse Wave Velocity (PWV) and ankle brachial index (ABI), The testing instrument is Omron Atherosclerosis Tester (BP-203RPEIII). During the test, the subjects need to expose their limbs, lie flat on the bed, and keep their bodies relaxed. At the same time, they need to tie cuffs around their limbs to avoid any physical movement and ensure the accuracy of the test results. The unit of PWV is (cm/s), and ABI is a numerical value. Changes in Pulse wave velocity and ankle brachial index before and after Intervention., 8 weeks|Volume Oxygen Maximum (VO2max), During the test, gradually increasing loads were performed using the Bruce running table protocol, and gas metabolism metrics were obtained at each stage of exercise using a portable Cortex-3B gas metabolism analyser. Changes in Volume oxygen maximum before and after Intervention., 8 weeks