user: Problem: Background: The primary role of red blood cells in the circulatory system is to transport oxygen to the tissues. The actual carrier of oxygen molecules is the protein hemoglobin, which binds to the oxygen and moves it throughout the body, releasing it in areas where the concentration of dissolved oxygen is low. A certain mutation in the gene for hemoglobin causes a slight change in the structure of this crucial protein, resulting in a disease called sickle-cell anemia. For people with this mutation, the hemoglobin produced by their red blood cells has a tendency to clump together, distorting the shape of the red blood cells and giving rise to the crescent-shaped cells seen above. By understanding the changes in structure that are the underlying cause of this disease, we have developed various ways to treat and manage this illness.  Paragraph: Dan had two children: Karen which had sickle-cell anemia, and his son Bob, which was healthy.  Given the paragraph above, please answer correctly the following question: Which child doesn't have a hemoglobin that gives rise to the crescent-shaped cells?

A: Bob


Problem: Given the question: Background: When you go to the dentist to get a tooth pulled, you really don’t want to feel any pain. The dentist injects an anesthetic into your gum and it eventually becomes numb. One theory as to why anesthetics work deals with the movement of ions across the cell membrane. The anesthetic gets into the membrane structure and causes shifts in how ions move across the membrane. If ion movement is disrupted, nerve impulses will not be transmitted and you will not sense pain – at least not until the anesthetic wears off.  Paragraph: Two men, Sam and Frodo, go into the doctor's office to have the exact same procedure done to one of their arms. They won't need to be knocked out for this, but they will be given anesthetic to help with the pain. After the nurse administers the anesthetic to both men, the ions in Sam's arm continue moving across the membrane, but the ions in Frodo's arm stop moving. The doctor then comes in to begin the procedure.  Given the paragraph above, please answer correctly the following question: Who will not experience pain when the doctor starts the procedure?
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The answer is:
Frodo


input question: Background: Many different chemical substances cause cancer. Dozens of chemicals in tobacco smoke, including nicotine, have been shown to cause cancer ( Figure below ). In fact, tobacco smoke is one of the main sources of chemical carcinogens. Smoking tobacco increases the risk of cancer of the lung, mouth, throat, and bladder. Using smokeless tobacco can also cause cancer. Other chemicals that cause cancer include asbestos, formaldehyde, benzene, cadmium, and nickel.  Paragraph: Walter and Jesse, two coworkers, are sitting at a hotel bar having a drink together after a long day at a conference when they start discussing their homes. Jesse says that he just recently discovered that the home he has been living in his entire life has had asbestos in it. Walter says that he has never lived in a home with asbestos.  Given the paragraph above, please answer correctly the following question: Is Jesse's chance of having cancer higher or lower than Walter's????
output answer: higher


Background: Another example of negative feedback has to do with blood glucose levels. When glucose (sugar) levels in the blood are too high, the pancreas secretes insulin to stimulate the absorption of glucose and the conversion of glucose into glycogen, which is stored in the liver. As blood glucose levels decrease, less insulin is produced. When glucose levels are too low, another hormone called glucagon is produced, which causes the liver to convert glycogen back to glucose.  Paragraph: Rob is studying medicine in a prestigious university. Today, his professor is teaching about blood glucose levels. He gave example of two patients, patient A and patient B. Patient A had high blood glucose level, but patient B had low blood glucose level. Rob was amazed to find how body keeps its balance.  Given the paragraph above, please answer correctly the following question: Which patient would secrete more insulin, patient A or patient B?
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Answer: patient A


Q: Background: When soil is flooded, hypoxia develops, as soil microorganisms consume oxygen faster than diffusion occurs. The presence of hypoxic soils is one of the defining characteristics of wetlands. Many wetland plants possess aerenchyma, and in some, such as water-lilies, there is mass flow of atmospheric air through leaves and rhizomes. There are many other chemical consequences of hypoxia. For example, nitrification is inhibited as low oxygen occurs and toxic compounds are formed, as anaerobic bacteria use nitrate, manganese, and sulfate as alternative electron acceptors. The reduction-oxidation potential of the rhizhosphere decreases and metal ions such as iron and manganese precipitate. Aerenchyma is a modification of the parenchyma.  Paragraph: Two farmers are having a conversation at a bar about how their soil is doing. Jeff takes a sip of his beer and says that he just discovered that his soil is hypoxic. Brandon is trying to get the attention of the bartender so he can order another martini. Upon hearing Jeff's remark about his soil, Brandon states that the soil on his own farm is not hypoxic. Brandon is relieved when he notices the bartender is finally walking over to them.  Given the paragraph above, please answer correctly the following question: Which person has soil with inhibited nitrification?
A: Jeff


[Q]: Background: Unfortunately, the layer of good ozone is being destroyed by air pollution. The chief culprits are chlorine and bromine gases. They are released in aerosol sprays, coolants, and other products. Loss of ozone has created an ozone hole over Antarctica. Ozone depletion results in higher levels of UV radiation reaching Earth. In humans, this increases skin cancers and eye cataracts. It also disturbs the nitrogen cycle, kills plankton, and disrupts ocean food webs. The total loss of the ozone layer would be devastating to most life. Its rate of loss has slowed with restrictions on pollutants, but it is still at risk.  Paragraph: Russian research spent most of their time in Antarctica to study the loss of ozone in the atmosphere. The Canadian team went north of the Polar Circle, close to the North Pole to do the same thing. They spent several months there. The Canadian team didn't find any ozone holes at the North Pole.  Given the paragraph above, please answer correctly the following question: Which team was more exposed to skin cancers?
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[A]:

assistant: Russian