Lok Sabha Question No. 64 (STARRED), answered on 2024-07-26
Subject: Affordable Prices of Cancer Drugs
Ministry: CHEMICALS AND FERTILIZERS
Asked by: Shri Hanuman Beniwal, Shri Pradeep Kumar Singh

## GOVERNMENT OF INDIA MINISTRY OF CHEMICALS & FERTILIZERS DEPARTMENT OF PHARMACEUTICALS

LOK SABHA STARRED QUESTION NO. † *64 TO BE ANSWERED ON 26 th  July, 2024

## Affordable Prices of Cancer Drugs

## †*64 Shri Hanuman Beniwal: Shri Pradeep Kumar Singh:

Will the Minister of CHEMICALS AND FERTILIZERS be pleased to state:

- (a)  whether  the  Government  is  aware  that  the  number  of  cancer  patients  in  the  country  is increasing year after year particularly among people from lower middle class;
- (b) if so, the steps taken/proposed to be taken by the Government to ensure the availability of cancer drugs to patients at affordable prices;
- (c) whether the National Pharmaceutical Pricing Authority has issued a notification to notify the maximum price of scheduled cancer drugs, if so, the details thereof; and
- (d)  whether  the  Government  has  ensured  large  scale  manufacturing  of  cancer  drugs  by pharmaceutical companies in the country and their distribution at affordable rates, if so, the Government's action plan thereto?

## ANSWER

MINISTER IN THE MINISTRY OF CHEMICALS & FERTILIZERS (SHRI JAGAT PRAKASH NADDA)

(a) to (d):  A statement is laid on the Table of the House.

Statement referred to in reply to the Lok Sabha Starred Question No. 64 (4 th  POSITION) for answer on 26.07.2024 raised by Shri Hanuman Beniwal and Shri Pradeep Kumar Singh regarding 'Affordable Prices of Cancer Drugs'

(a): As  per  the  Indian  Council  of  Medical  Research  (ICMR)  -  National  Cancer  Registry Programme (ICMR-NCRP), under the Ministry of Health & Family Welfare, the estimated number of incidence of cancer cases in the country for the year 2021 to 2024 is given below:

| Year                                | 2021      | 2022      | 2023      | 2024      |
|-------------------------------------|-----------|-----------|-----------|-----------|
| Estimated incidence of cancer cases | 14,26,447 | 14,61,427 | 14,96,972 | 15,33,055 |

(b) to (c):  The National Pharmaceutical Pricing Authority (NPPA) under the Department of Pharmaceuticals (DoP) has fixed the ceiling prices of 131 anti-cancer scheduled formulations included  in  Scheduled-I  of  the  Drugs  (Prices  Control)  Order,  2013  (DPCO,  2013)  under National List of Essential medicines (NLEM) 2015 and 2022. Of the 131 anti-cancer drugs for which ceiling prices were fixed, 120 formulations are under NLEM 2022. This has resulted in the reduction of around 20 percent in the ceiling prices from the existing ceiling price under NLEM, 2015 leading to annual savings of around Rs. 294 Crore to the patients. The list of 131 formulations along with their ceiling prices is at Annexure I. NPPA has also fixed retail price of  28  Anti-Cancer  formulations  as  on  22.07.2024  which  are  applicable  to  the  applicant manufacturing and marketing company.

NPPA vide order S.O. 1041 (E) dated 27 th February, 2019, put a cap of 30% Trade Margin on 42 selected non-scheduled anti-cancer medicines under 'Trade Margin Rationalization' approach. By this approach, the Maximum Retail Price (MRP) of 526 brands of these medicines were reduced by average around 50 percent, resulting in annual savings of around Rs. 984 Crore to the patients. The details of revised prices are available on the website of the NPPA, i.e., nppaindia.nic.in.

The government ensures that the scheduled drugs for cancer are not sold above their ceiling price fixed by NPPA and non-scheduled drugs do not avail increase in MRP beyond 10 percent in preceding 12 months.  DPCO, 2013 provide for deposition of overcharge amount by the manufacturers in case of default in implementing the provisions of this Order.

Further,  under  Pradhan  Mantri  Bhartiya  Janaushadhi  Pariyojana  (PMBJP),  quality medicine at affordable prices is offered to people. The price of Jan Aushadhi medicines are cheaper by at least by 50%, and in some cases, by 80% to 90% of the market price of branded medicines available in the market. 83 products for cancer treatment have been brought under the basket of drugs offered by Jan Aushadhi Kendras. The list of 83 products is at Annexure II.

In addition, support to cancer patients is also provided by Ministry of Health and Family Welfare (MoHFW). As per the information provided by MoHFW support is extended under following scheme/initiative:

i.  Ayushman  Bharat  Pradhan  Mantri  Jan  Arogya  Yojana  (AB  PM-JAY):   provides treatment corresponding to a total of 1,949 procedures under 27 different specialties including oncology, nephrology, cardiology and general medicine, etc. Health Benefit Packages (HBP) covers all the costs related to treatment, including drugs, supplies, diagnostic  services,  physician's  fees,  room  charges,  surgeon  charges,  OT  and  ICU

charges, etc.  Further, 37.76 lakhs hospital admissions amounting to Rs.7,130 crores have been authorized under the scheme for treatment related to cancer.

ii.  Affordable Medicines and Reliable Implants for Treatment (AMRIT), an initiative launched by the MoHFW, aims to provide affordable medicines for treatment of cancer, cardiovascular and other diseases. AMRIT Pharmacies spread across 29 States/Union Territories,  are  selling  more  than  5,200  drugs  (including  cardiovascular,  cancer, diabetes,  stents,  etc),  implants,  surgical  disposables  and  other  consumables  at  a significant discounts upto 50% on market rates.

(d): The DoP  is implementing the Production Linked Incentive (PLI) Scheme  for Pharmaceuticals with total financial outlay of Rs. 15,000 crore to enhance manufacturing of critical  drugs  in  the  country.  The  product  categories  covered  under  the  scheme inter  alia include anti-cancer drugs etc. The anti-cancer drugs approved under the scheme are given at Annexure III.

## Ceiling Prices of Anti-Cancer Formulation (as on 22.07.2024)

| S.N.   | Name of the Scheduled Formulation   | Dosage form and strength     | Unit      | Current Ceiling Price (Rs.)   |
|--------|-------------------------------------|------------------------------|-----------|-------------------------------|
| (1)    | (2)                                 | (3)                          | (4)       | (5)                           |
| 1      | 5-Fluorouracil                      | Injection 250 mg/5 ml        | 1 ml      | 2.90                          |
| 2      | 6-Mercaptopurine                    | Tablet 50mg                  | 1 Tablet  | 5.26                          |
| 3      | Actinomycin D                       | Powder for Injection 0.5mg   | 1 Vial    | 331.03                        |
| 4      | Allopurinol                         | Tablet 100mg                 | 1 Tablet  | 1.89                          |
| 5      | Amitriptyline                       | Tablet 25mg                  | 1 Tablet  | 2.49                          |
| 6      | Amitriptyline                       | Tablet 10mg                  | 1 Tablet  | 2.39                          |
| 7      | Arsenic Trioxide                    | Injection 1mg/ml             | 1 ml      | 67.60                         |
| 8      | Azathioprine                        | Tablet 50mg                  | 1 Tablet  | 11.26                         |
| 9      | Bendamustine hydrochloride          | Injection 100 mg/vial        | 1 Vial    | 4946.80                       |
| 10     | Bicalutamide                        | Tablet 50mg                  | 1 Tablet  | 43.30                         |
| 11     | Bleomycin                           | Powder for Injection 15units | 1 Vial    | 677.41                        |
| 12     | Bortezomib                          | Powder for Injection 2mg     | 1 Vial    | 5260.50                       |
| 13     | Calcium folinate                    | Tablet 15mg                  | 1 Tablet  | 47.54                         |
| 14     | Capecitabine                        | Tablet 500mg                 | 1 Tablet  | 112.73                        |
| 15     | Carboplatin                         | Injection 10mg/mL            | 1 ML      | 59.07                         |
| 16     | Chlorambucil                        | Tablet 2 mg                  | 1 Tablet  | 45.95                         |
| 17     | Chlorambucil                        | Tablet 5 mg                  | 1 Tablet  | 103.26                        |
| 18     | Cisplatin                           | Injection 1mg/mL             | 1 ML      | 7.09                          |
| 19     | Cyclophosphamide                    | Tablet 50mg                  | 1 Tablet  | 3.73                          |
| 20     | Cyclophosphamide                    | Powder for Injection 500mg   | 1 Vial    | 73.48                         |
| 21     | Cyclosporine                        | Capsule 50 mg                | 1 Capsule | 55.11                         |
| 22     | Cyclosporine                        | Capsule 25 mg                | 1 Capsule | 28.04                         |
| 23     | Cyclosporine                        | Capsule 100mg                | 1 Capsule | 103.12                        |
| 24     | Cyclosporine                        | Oral liquid 100mg/mL(p)      | 1 ML      | 80.58                         |
| 25     | Cytosine arabinoside                | Injection 1000mg/vial        | 1 Vial    | 1130.33                       |
| 26     | Cytosine arabinoside                | Injection 500mg/vial         | 1 Vial    | 536.33                        |
| 27     | Cytosine arabinoside                | Injection 100mg/vial         | 1 Vial    | 139.59                        |
| 28     | Dacarbazine                         | Powder for Injection 200mg   | 1 Vial    | 381.75                        |
| 29     |                                     | Powder for Injection 500mg   | 1 Vial    | 518.83                        |
| 30     | Dacarbazine Dexamethasone           | Injection 4mg/mL (5 ML)      | 1 ML      | 2.57                          |
| 31     | Dexamethasone                       | Tablet 0.5mg                 | 1 Tablet  | 0.22                          |
| 32     | Dexamethasone                       | Injection 4mg/mL (2 ML)      | 1 ML      | 5.09                          |

| S.N.   | Name of the Scheduled Formulation   | Dosage form and strength         | Unit      | Current Ceiling Price (Rs.)   |
|--------|-------------------------------------|----------------------------------|-----------|-------------------------------|
| (1)    | (2)                                 | (3)                              | (4)       | (5)                           |
| 33     | Dexamethasone                       | Tablet 4 mg                      | 1 Tablet  | 4.62                          |
| 34     | Dexamethasone                       | Injection 4mg/mL (Pack of 10ML)  | 1 ML      | 1.57                          |
| 35     | Dexamethasone                       | Injection 4mg/mL (Pack of 20 ML) | 1 ML      | 1.35                          |
| 36     | Dexamethasone                       | Injection 4mg/mL (Pack of 30ML)  | 1 ML      | 0.90                          |
| 37     | Diazepam                            | Tablet 5 mg                      | 1 Tablet  | 1.63                          |
| 38     | Diazepam                            | Tablet 2 mg                      | 1 Tablet  | 1.44                          |
| 39     | Diazepam                            | Injection 5mg/mL                 | 1 ML      | 5.54                          |
| 40     | Docetaxel                           | Powder for Injection 20mg        | 1 Vial    | 2868.39                       |
| 41     | Docetaxel                           | Powder for Injection 80mg        | 1 Vial    | 10333.69                      |
| 42     | Doxorubicin                         | Injection2mg/mL                  | 1 ML      | 31.75                         |
| 43     | Etoposide                           | Capsule 50mg                     | 1 Capsule | 56.63                         |
| 44     | Etoposide                           | Injection 20mg/mL                | 1 ML      | 34.51                         |
| 45     | Filgrastim                          | Injection 300mcg                 | 1 Vial    | 1159.97                       |
| 46     | Fluoxetine                          | Capsule 20 mg                    | 1 Capsule | 3.99                          |
| 47     | Fluoxetine                          | Tablet 20 mg                     | 1 Tablet  | 4.15                          |
| 48     | Gefitinib                           | Tablet 250mg                     | 1 Tablet  | 237.14                        |
| 49     | Gemcitabine                         | Powder for Injection 200 mg      | 1 Vial    | 1299.80                       |
| 50     | Gemcitabine                         | Powder for Injection 1000mg      | 1 Vial    | 5592.55                       |
| 51     | Haloperidol                         | Injection 5mg/mL                 | 1 ML      | 6.51                          |
| 52     | Haloperidol                         | Tablet 5mg                       | 1 Tablet  | 3.57                          |
| 53     | Haloperidol                         | Tablet 1.5mg                     | 1 Tablet  | 1.58                          |
| 54     | Hydroxyurea                         | Capsule 500mg                    | 1 Capsule | 12.12                         |
| 55     | Ifosfamide                          | Powder for Injection 1000mg      | 1 Vial    | 318.96                        |
| 56     | Ifosfamide                          | Powder for Injection 2000mg      | 1 Vial    | 643.16                        |
| 57     | Imatinib                            | Capsule 100mg                    | 1 Capsule | 73.48                         |
| 58     | Imatinib                            | Tablet 100mg                     | 1 Tablet  | 69.75                         |
| 59     | Imatinib                            | Tablet 400mg                     | 1 Tablet  | 199.62                        |
| 60     | Irinotecan HCltrihydrate            | Solution for injection 20mg/mL   | 1 ML      | 964.89                        |
| 61     | Lactulose                           | Oral liquid 10 g/15mL            | 1 ML      | 1.23                          |
| 62     | L-Asparaginase                      | Powder for Injection 10000KU     | 1 Vial    | 1707.74                       |
| 63     | L-Asparaginase                      | Powder for Injection 5000 KU     | 1 Vial    | 1034.88                       |
| 64     | Lenalidomide                        | Capsule 5mg                      | 1 Capsule | 67.25                         |
| 65     | Lenalidomide                        | Capsule 25 mg                    | 1 Capsule | 292.28                        |

| S.N.   | Name of the Scheduled Formulation   | Dosage form and strength                    | Unit          | Current Ceiling Price (Rs.)   |
|--------|-------------------------------------|---------------------------------------------|---------------|-------------------------------|
| (1)    | (2)                                 | (3)                                         | (4)           | (5)                           |
| 66     | Letrozole                           | Tablet 2.5mg                                | 1 Tablet      | 29.32                         |
| 67     | Leuprolide acetate                  | Powder for injection 11.25mg                | 1 Vial        | 9294.48                       |
| 68     | Leuprolide acetate                  | Powder for injection 22.5 mg                | 1 Vial        | 17081.50                      |
| 69     | Leuprolide acetate                  | Powder for injection 3.75 mg                | 1 Vial        | 3112.67                       |
| 70     | Loperamide                          | Tablet 2mg                                  | 1 Tablet      | 2.28                          |
| 71     | Loperamide                          | Capsule 2mg                                 | 1 Capsule     | 3.79                          |
| 72     | Melphalan                           | Tablet 2 mg                                 | 1 Tablet      | 122.14                        |
| 73     | Melphalan                           | Tablet 5 mg                                 | 1 Tablet      | 209.49                        |
| 74     | Mesna                               | Injection 100mg/mL                          | 1 ML          | 15.51                         |
| 75     | Methotrexate                        | Tablet 5mg                                  | 1 Tablet      | 9.43                          |
| 76     | Methotrexate                        | Tablet 2.5mg                                | 1 tablet      | 5.31                          |
| 77     | Methotrexate                        | Tablet 10mg                                 | 1 tablet      | 13.29                         |
| 78     | Metoclopramide                      | Tablet 10mg                                 | 1 Tablet      | 1.35                          |
| 79     | Metoclopramide                      | Injection 5mg/mL (Less than 10ML Pack)      | 1 ML          | 2.67                          |
| 80     | Metoclopramide                      | Oral liquid 5mg/5mL(p)                      | 1 ML          | 0.50                          |
| 81     | Metoclopramide                      | Injection 5mg/mL (10 ML&More Pack)          | 1 ML          | 1.62                          |
| 82     | Midazolam                           | Injection 1mg/mL                            | 1 ML          | 5.92                          |
| 83     | Mycophenolate mofetil               | Tablet 250mg                                | 1 Tablet      | 49.60                         |
| 84     | Mycophenolate mofetil               | Tablet 500mg                                | 1 Tablet      | 73.88                         |
| 85     |                                     | Oral liquid                                 |               | 1.25                          |
| 86     | Ondansetron Ondansetron             | 2mg/5mL(p) Tablet 4 mg                      | 1 ML 1 Tablet | 5.14                          |
| 87     | Ondansetron                         | Injection 2mg/mL                            | 1 ML          | 5.96                          |
| 88     | Ondansetron                         | Tablet 8 mg                                 | 1 Tablet      | 9.06                          |
| 89     | Oxaliplatin                         | Injection 5 mg/mL in 10 mLvial              | 1 Vial        | 2233.95                       |
| 90     | Oxaliplatin                         | Injection 100mg(as licensed)                | Each Vial     | 4979.68                       |
| 91     |                                     | Injection 30 mg/5 mL, injection 100 mg/16.7 |               | 215.44                        |
| 92     | Paclitaxel Prednisolone             | ml Tablet 20mg                              | 1 ML 1 Tablet | 2.40                          |
| 93     | Prednisolone                        | Tablet 10mg                                 | 1 Tablet      | 1.20                          |
| 94     | Prednisolone                        | Tablet 40mg                                 | 1 Tablet      | 3.41                          |
| 95     | Prednisolone                        | Oral liquid 15mg/5mL(p)                     | 1 ML          | 0.86                          |
| 96     | Prednisolone                        | Oral liquid 5mg/5mL(p)                      | 1 ML          | 0.49                          |

| S.N.   | Name of the Scheduled Formulation   | Dosage form and strength                  | Unit           | Current Ceiling Price (Rs.)   |
|--------|-------------------------------------|-------------------------------------------|----------------|-------------------------------|
| (1)    | (2)                                 | (3)                                       | (4)            | (5)                           |
| 97     | Rituximab                           | Injection 10mg/mL                         | 1 ML           | 761.81                        |
| 98     | Tacrolimus                          | Tablet 1 mg                               | 1 Tablet       | 39.98                         |
| 99     | Tacrolimus                          | Tablet 2 mg                               | 1 Tablet       | 77.69                         |
| 100    | Tacrolimus                          | Tablet 0.5 mg                             | 1 Tablet       | 20.97                         |
| 101    | Tacrolimus                          | Capsule 2mg                               | 1 Capsule      | 84.34                         |
| 102    | Tacrolimus                          | Capsule 0.5mg                             | 1 Capsule      | 20.66                         |
| 103    | Tacrolimus                          | Capsule 1mg                               | 1 Capsule      | 40.62                         |
| 104    | Tamoxifen                           | Tablet 20mg                               | 1 Tablet       | 2.95                          |
| 105    | Tamoxifen                           | Tablet 10mg                               | 1 Tablet       | 2.21                          |
| 106    | Temozolomide                        | Tablet 250 mg                             | 1 Tablet       | 3758.15                       |
| 107    | Temozolomide                        | Capsule 250mg                             | 1 Capsule      | 4304.01                       |
| 108    | Temozolomide                        | Tablet 20 mg                              | 1 Tablet       | 336.65                        |
| 109    | Temozolomide                        | Capsule 20 mg                             | 1 Capsule      | 441.33                        |
| 110    | Temozolomide                        | Capsule 100mg                             | 1 Capsule      | 1508.70                       |
| 111    | Thalidomide                         | Capsule 100mg                             | 1 Capsule      | 62.01                         |
| 112    | Thalidomide                         | Capsule 50 mg                             | 1 Capsule      | 31.16                         |
| 113    | Tramadol                            | Tablet 100 mg                             | 1 Tablet       | 24.49                         |
| 114    | Tramadol                            | Tablet 50 mg                              | 1 Tablet       | 9.70                          |
| 115    |                                     | Injection 50mg/mL                         |                | 11.79                         |
| 116    | Tramadol Tramadol                   | (upto 2ml pack) Capsule 50mg              | 1 ML 1 Capsule | 4.82                          |
| 117    | Tramadol                            | Capsule 100mg                             | 1 Capsule      | 9.04                          |
| 118    | Trastuzumab                         | Injection 440mg/50mL                      | 1 Vial         | 54725.21                      |
| 119    | Vincristine                         | Injection 1mg/mL                          | 1 ML           | 57.52                         |
| 120    | Zoledronic acid                     | Powder for Injection 4mg                  | 1 Vial         | 2392.05                       |
| 121    | All-trans Retinoic Acid             | Capsule 10 mg                             | 1 Capsule      | 101.85                        |
| 122    | Cyclosporine                        | Injection 50 mg/ml                        | 1 ml           | 335.80                        |
| 123    |                                     | Powder for I.V. Injection 20 mg (5 mg/ml) |                | 302.76                        |
|        | Daunarubicin                        |                                           | Each pack      |                               |
| 124    | Imatinib                            | Capsule 400 mg                            | 1 Capsule      | 318.01                        |
| 125    | Methotrexate                        | Injection 50 mg/ml                        | 1 ml           | 49.86                         |
| 126    | Morphine                            | Tablet 10 mg                              | 1 Tablet       | 6.63                          |
| 127    | Morphine                            | SR Tablet 30 mg                           | 1 Tablet       | 6.78                          |
| 128    | Prednisolone                        | Injection 20 mg/2ml                       | 1 ml           | 4.46                          |
| 129    | Temozolomide                        | Tablet 100 mg                             | 1 Tablet       | 1925.59                       |
| 130    | Tramadol                            | Injection 50 mg/ml (20 ml Pack)           | 1 ml           | 1.55                          |
| 131    | Vinblastine                         | Injection 1mg/ml                          | 1 ml           | 25.54                         |

|         |                                            |             | Annexure II   |
|---------|--------------------------------------------|-------------|---------------|
| Sl. No. | Name of the Medicine/Product               | Unit        | MRP (in Rs.)  |
| 1       | Bleomycin Injection IP 15 IU               | Vial        | 300.00        |
| 2       | Cisplatin Injection IP 10 mg per10ml       | Vial        | 35.00         |
| 3       | Cisplatin Injection BP 50mg/50ml           | Vial        | 156.00        |
| 4       | Doxorubicin Injection IP 50mg (2mg per ml) | Vial        | 300.00        |
| 5       | Etoposide Injection IP 100 mg per 5 ml     | Vial        | 99.00         |
| 6       | Gemcitabine 1000 mg Injection IP           | Vial        | 836.00        |
| 7       | Gemcitabine Injection IP 200mg             | Vial        | 240.00        |
| 8       | Tamoxifen Citrate Tablets IP 10 mg         | 10's        | 11.00         |
| 9       | Tamoxifen Citrate Tablets IP 20 mg         | 10's        | 16.00         |
| 10      | Trastuzumab Injection 440 mg With Wfi      | 1's         | 15000.00      |
| 11      | Methotrexate Tablets IP 7.5 mg             | 10's        | 25.00         |
| 12      | Megestrol Acetate Tablets IP 40mg          | 10's        | 140.00        |
| 13      | Anastrozole Tablets IP 1mg                 | 10's        | 78.00         |
| 14      | Bicalutamide Tablets IP 50mg               | 10's        | 137.00        |
| 15      | Bortezomib Injection IP 3.5 mg             | Vial        | 990.00        |
| 16      | Dacarbazine Injection 200mg                | VIAL        | 188.00        |
| 17      | Daunorubicin HCl Injection 20mg            | vial        | 204.00        |
| 18      | Imatinib Mesylate Tablets IP 400mg         | 10's        | 225.00        |
| 19      | Lenalidomide Capsules 10mg                 | 10's        | 464.00        |
| 20      | Letrozole Tablets IP 2.5mg                 | 10's        | 34.00         |
| 21      | Leuprolide Acetate Injections 3.75mg       | 1's         | 1800.00       |
| 22      | Oxaliplatin Injections IP 50mg             | Vial        | 475.00        |
| 23      | Paclitaxel Injection IP 100mg (6mg/ml)     | Vial        | 540.00        |
| 24      | 5-Flurouracil Inj. 500mg                   | 10 ml       | 11.50         |
| 25      | Carboplatin Injection 150mg                | 15 ml Vial  | 375.00        |
| 26      | Carboplatin Injection IP 450mg             | 45 ml Vial  | 1707.00       |
| 27      | Cyclophosphamide 500 mg injection          | VIAL        | 35.00         |
| 28      | Hydroxyurea Capsules IP 500mg              | 10's        | 66.00         |
| 29      | Ifosfamide Inj. 1GM                        | VIAL        | 170.00        |
| 30      | Docetaxel Injection IP 80 mg               | VIAL        | 1800.00       |
| 31      | Docetaxel Injection IP 120 mg              | VIAL        | 2700.00       |
| 32      | Erlotinib Tablets IP 150 mg                | 10's Bottle | 700.00        |
| 33      | Gefitinib Tablets IP 250 mg                | 10's        | 440.00        |

|   Sl. No. | Name of the Medicine/Product                             | Unit                              |   MRP (in Rs.) |
|-----------|----------------------------------------------------------|-----------------------------------|----------------|
|        34 | Pemetrexed Injection IP 100 mg                           | VIAL                              |            810 |
|        35 | Pemetrexed Injection IP 500 mg                           | VIAL                              |           2310 |
|        36 | Temozolomide Capsules IP 100mg                           | 5's in Bottle                     |           1463 |
|        37 | Temozolomide Capsules IP 250 mg                          | 5's                               |           2685 |
|        38 | Capecitabine Tablets IP 500mg                            | 10's                              |            250 |
|        39 | Etoposide Capsules IP 50 mg                              | 8's                               |            216 |
|        40 | Methotrexate Tablets IP 2.5mg                            | 10's                              |             15 |
|        41 | Methotrexate Tablets IP 10mg                             | 10's                              |             30 |
|        42 | Methotrexate Tablets IP 5mg                              | 10's                              |             20 |
|        43 | Dasatinib 50mg Tablets                                   | 60's Bottle                       |           1100 |
|        44 | Lenalidomide Capsules 25mg                               | 30's in PET bottle in Mono Carton |           1480 |
|        45 | Lenalidomide Capsules 5mg                                | 30's in PET bottle in Mono Carton |            380 |
|        46 | Thalidomide Capsules 100mg                               | 10's                              |            160 |
|        47 | Thalidomide Capsules 50mg                                | 10's                              |             90 |
|        48 | Lapatinib Tablets IP 250mg                               | 30's Bottle                       |           2710 |
|        49 | Bortezomib 2mg powder for Injection                      | Vial with WFI                     |            710 |
|        50 | Dasatinib Tablets 20mg                                   | 60's Bottle in Monopack           |           1285 |
|        51 | Dasatinib Tablets 50mg                                   | 60's Bottle in Monopack           |           2365 |
|        52 | Dasatinib Tablets 70mg                                   | 60's Bottle in Monopack           |           2999 |
|        53 | Methotrexate Tablets IP 15mg                             | 10's                              |             35 |
|        54 | Methotrexate Tablets IP 20mg                             | 10's                              |             45 |
|        55 | Pazopanib Tablets 200mg                                  | 30's bottle in Monopack           |           2200 |
|        56 | Pazopanib Tablets 400mg                                  | 30's bottle in Monopack           |           3100 |
|        57 | Sorafenib Tablets 200mg                                  | 30's bottle in Monopack           |           3000 |
|        58 | Sunitinib Capsules 12.5mg                                | 10's                              |            499 |
|        59 | Sunitinib Capsules 25mg                                  | 10's                              |            910 |
|        61 |                                                          | 10's                              |            250 |
|        60 | Temozolomide Capsules IP 20mg Thalidomide Capsules 200mg | 10's                              |            335 |

|   Sl. No. | Name of the Medicine/Product                                | Unit                    | MRP (in Rs.)                  |
|-----------|-------------------------------------------------------------|-------------------------|-------------------------------|
|        62 | Rituximab 100mg/10ml Injection                              | 10ml vial               | New (Under Tendering Process) |
|        63 | Rituximab 500mg/50ml Injection                              | 50ml vial               | New (Under Tendering Process) |
|        64 | Abiraterone Acetate Tablets 250mg                           | 120's bottle            | New (Under Tendering Process) |
|        65 | Nintedanib Soft gelatin Capsules 150mg                      | 10's                    | New (Under Tendering Process) |
|        66 | Pomalidomide 2mg Capsules                                   | 21's in bottle          | New (Under Tendering Process) |
|        67 | Bortezomib 2.5mg powder for Injection                       | Vial with WFI           | New (Under Tendering Process) |
|        68 | Crizotinib Capsules 250mg                                   | 60's Bottle in Monopack | New (Under Tendering Process) |
|        69 | Nintedanib Soft Gelatin Capsules 100mg                      | 10's                    | New (Under Tendering Process) |
|        70 | Methotrexate Injection IP 25mg/ml                           | 1ml Ampoule             | New (Under Tendering Process) |
|        71 | Methotrexate Injection IP 50mg/2ml                          | 2ml Ampoule             | New (Under Tendering Process) |
|        72 | Panitumumab 100mg Infusion                                  | 5ml Vial                | New (Under Tendering Process) |
|        73 | Panitumumab 400mg Infusion                                  | 20ml Vial               | New (Under Tendering Process) |
|        74 | Cabozantinib Tablets 20 mg                                  | 30's bottle             | New (Under Tendering Process) |
|        75 | Cabozantinib Tablets 40 mg                                  | 30's bottle             | New (Under Tendering Process) |
|        76 | Cabozantinib Tablets 60 mg                                  | 30's bottle             | New (Under Tendering Process) |
|        77 | Octreotide long acting release Injection 20mg (Lyophilised) | Vial                    | New (Under Tendering Process) |
|        78 | Octreotide long acting release Injection 30mg (Lyophilised) | Vial                    | New (Under Tendering Process) |

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|   Sl. No. | Name of the Medicine/Product   | Unit           | MRP (in Rs.)                  |
|-----------|--------------------------------|----------------|-------------------------------|
|        79 | Octreotide injection 50 mcg    | 1ml Ampoule    | New (Under Tendering Process) |
|        80 | Octreotide injection 100mcg    | 1ml Ampoule    | New (Under Tendering Process) |
|        81 | Olaparib Tablet 100 mg         | 30's in bottle | New (Under Tendering Process) |
|        82 | Olaparib Tablet 150 mg         | 30's in bottle | New (Under Tendering Process) |
|        83 | Vincristine Injection 1mg      | 1ml Vial       | New (Under Tendering Process) |

## The List of anti-cancer Drugs approved under PLI Scheme for Pharmaceuticals

|   S. No. | Generic Name of the Product            |
|----------|----------------------------------------|
|        1 | 5-Fluorouracil                         |
|        2 | Abiraterone                            |
|        3 | Abiraterone acetate                    |
|        4 | Acalabrutinib                          |
|        5 | Afatinib                               |
|        6 | ALECTINIB Tablet                       |
|        7 | Anastrozole                            |
|        8 | Apalutamide                            |
|        9 | Arsenic Trioxide                       |
|       10 | Asenapine Maleate                      |
|       11 | Asparaginase                           |
|       12 | Axitinib                               |
|       13 | Azacitidine                            |
|       14 | Bendamustine                           |
|       15 | Bevacizumab                            |
|       16 | BEXAROTENE                             |
|       17 | Bicalutimide                           |
|       18 | Bleomycin                              |
|       19 | BORTEZOMIB                             |
|       20 | Bosutinib Monohydrate                  |
|       21 | Busulphan                              |
|       22 | Cabazitaxel                            |
|       23 | Cabozantinib                           |
|       24 | Calcium Folinate                       |
|       25 | Capecitabine                           |
|       26 | Capecitabine + Cyclophosphamide Tablet |
|       27 | Carboplatin                            |
|       28 | Carfilzomib                            |
|       29 | Carmustine                             |
|       30 | CASPOFUNGIN                            |
|       31 | Chlorambucil                           |
|       32 | Cisplatin                              |
|       33 | Clofarabine                            |
|       34 | Cyclophosphamide                       |
|       35 | Cytarabine + Daunorubicin              |
|       36 | Cytarabine                             |
|       37 | Daratumumab                            |
|       38 | Dasatanib                              |
|       39 | Daunorubicin + Cytarabine TBD          |
|       40 | Decitabine                             |
|       41 | Degarelix acetate                      |

|   42 | DOCETAXEL                                   |
|------|---------------------------------------------|
|   43 | Doxorubicin Hydrochloride                   |
|   44 | Enzalutamide                                |
|   45 | Epirubicin                                  |
|   46 | Eribulin                                    |
|   47 | Erlotinib Hydrochloride                     |
|   48 | Erwinase                                    |
|   49 | Erythropoietin                              |
|   50 | Etoposide                                   |
|   51 | Everolimus (Zortress, Afinitor and Disperz) |
|   52 | EXEMESTANE                                  |
|   53 | Filgrsatim                                  |
|   54 | Fluorouracil                                |
|   55 | Fulvestrant                                 |
|   56 | Fulvestrant + Ethanol                       |
|   57 | Gefitinib                                   |
|   58 | GEMCITABINE                                 |
|   59 | GOSERELIN                                   |
|   60 | Hydromorphone                               |
|   61 | Hydroxyurea                                 |
|   62 | Ibrutinib                                   |
|   63 | IMATINIB                                    |
|   64 | Imatinib Mesylate                           |
|   65 | Imiquimod                                   |
|   66 | IRINOTECAN                                  |
|   67 | Irinotecan Hcl Injection                    |
|   68 | Lanreoride Acetate                          |
|   69 | Lapatinib 250mg                             |
|   70 | LEFLUNOMIDE                                 |
|   71 | Lenalidomide                                |
|   72 | Lenvatinib                                  |
|   73 | Letrozole                                   |
|   74 | LEUCOVORIN                                  |
|   75 | LEUPROLIDE                                  |
|   76 | Leuprolide Acetate                          |
|   77 | Levoleucovorin Calcium                      |
|   78 | Megestrol Acetate                           |
|   79 | MELPHALAN                                   |
|   80 | Mesna                                       |
|   81 | METHOTREXATE                                |
|   82 | MIDOSTAURIN                                 |
|   83 | Mitomycin                                   |
|   84 | Nab-Paclitaxel                              |
|   85 | Nelarabine                                  |
|   86 | Nilotinib                                   |
|   88 | NINTEDANIB                                  |

|   89 | Niraparib                                                      |
|------|----------------------------------------------------------------|
|   90 | NIVOLUMAB                                                      |
|   91 | OCTREOTIDE                                                     |
|   92 | Olaparib                                                       |
|   93 | Osirmetinib                                                    |
|   94 | Oxaliplatin                                                    |
|   95 | Paclitaxel (Protein-bound particles) for Injectable Suspension |
|   96 | PALBOCICLIB                                                    |
|   97 | Panobinostat 20mg                                              |
|   98 | Pazopanib                                                      |
|   99 | Pegaspargase                                                   |
|  100 | Pegfilgrastim                                                  |
|  101 | Peglypodoxorubicin                                             |
|  102 | Pemetrexed                                                     |
|  103 | Pertuzumab                                                     |
|  104 | Pirfenidone                                                    |
|  105 | PLERIXAFOR                                                     |
|  106 | Pomalidomide                                                   |
|  107 | Prednisone                                                     |
|  108 | Prochlorperazine HCL                                           |
|  109 | Relugolix                                                      |
|  110 | Rituximab                                                      |
|  111 | Romidepsin                                                     |
|  112 | Ruxolitinib                                                    |
|  113 | Sargamostim                                                    |
|  114 | Sorafenib Tosylate                                             |
|  115 | Sunitinib                                                      |
|  116 | Tamoxifen Citrate                                              |
|  117 | Temozolomide                                                   |
|  118 | Thiotepa                                                       |
|  119 | Tipiracil + Trifluridine Tab                                   |
|  120 | TOFACITINIB                                                    |
|  121 | Topotecan                                                      |
|  122 | Toremifene Citrate                                             |
|  123 | Trabectedin                                                    |
|  124 | Trastuzumab                                                    |
|  125 | TRASTUZUMAB EMTANSINE                                          |
|  126 | Trifluradine                                                   |
|  127 | Trifluradine + Tiperacil                                       |
|  128 | Triptorelin Pamoate                                            |
|  129 | Tucatinib                                                      |
|  130 | Venetoclax                                                     |
|  131 | Vincristine sulphate                                           |