Lok Sabha Question No. 716 (UNSTARRED), answered on 2024-07-26
Subject: Research on Medicinal Plants
Ministry: AYUSH
Asked by: Dr. Jayanta Kumar Roy, Shri Matheswaran V S

## GOVERNMENT OF INDIA MINISTRY OF AYUSH LOK SABHA UNSTARRED QUESTION NO. 716 TO BE ANSWERED ON 26.07.2024

## 'Research on Medicinal Plants'

## 716. Dr. Jayanta Kumar Roy:

## Shri Matheswaran V S:

Will the Minister of  Ayush be pleased to state:

(a)  whether  the  Government  has  established/proposes  to  establish  any  research  centres  to promote research and development on medicinal plants in the country including North West Bengal;

(b)  if  so,  the  details  of  thereof,  State/UT-wise  along  with  the  details  of  ongoing  projects pertaining to medicinal plants and if not, the reason therefor;

(c)  whether  the  Government  has  conducted  any  survey  regarding  availability  of  medicinal plants  in  the  Kolli  Hills  region  of  Namakkal  district  of  Tamil  Nadu  and  if  so,  the  details thereof;

(d)  whether  the  Government  has  any  plan  to  set  up  Herbarium  and  Museum  based  on medicinal  plants  at  Kolli  Hills  region  of  Namakkal  district  of  Tamil  Nadu  and  if  so,  the details thereof?

## ANSWER

## MINISTER OF STATE (INDEPENDENT CHARGE) MINISTRY OF AYUSH

## (SHRI PRATAPRAO JADHAV)

Ans.  (a  &  b): Yes  Sir,  Presently,  various  Research  Institutes/Centres/Units  of  different Research Councils under the Ministry of Ayush, Government of India, viz. Central Council for  Research  in  Ayurvedic  Sciences  (CCRAS),  Central  Council  for  Research  in  Unani Medicine  (CCRUM),  Central  Council  for  Research  in  Homoeopathy  (CCRH),  Central Council  for  Research  in  Siddha  (CCRS),  North  Eastern  Institute  of  Ayurveda  &  Folk Medicine Research (NEIAFMR) and the National Institute of Sowa Rigpa (NISR), have been established and engaged in the area of medicinal plant research across the country. State/UTwise details of the Institutes/Centres are appended in Annexure-I.

Further,  various  national  institutes  under  the  Ministry  of  Ayush,  viz.  All  India Institute  of  Ayurveda  (AIIA),  New  Delhi;  National  Institute  of  Ayurveda  (NIA),  Jaipur; National Institute of Unani Medicine (NIUM), Bangalore; National Institute of Siddha (NIS), Chennai;  Institute  of  Teaching  and  Research  in  Ayurveda,  (ITRA),  Institute  of  National

Importance  (INI),  Jamnagar  and  North  Eastern  Institute  of  Ayurveda  and  Homoeopathy (NEIAH),  Shillong  are  the  apex  institutes,  also  involved  in  academic  research  activities related to medicinal plants in the concerned systems of medicines across the country.

In  addition,  the  constituent  laboratory  of  the  Council  of  Scientific  &  Industrial Research (CSIR) is a frontier organization working on medicinal plant research through its various laboratories/centres across the country. State/UT-wise details are placed in Annexure-II.

Further,  the  Indian  Council  of  Medical  Research  (ICMR),  through  its  National Institute of Traditional  Medicine  (NITM),  Belagavi,  Karnataka, conduct research on Traditional Medicine; the Institute is working on documentation and validation (in silico, in vitro, in vivo and clinical evaluation) of various selected medicinal plants.

Besides,  the  Directorate  of  Medicinal  and  Aromatic  Plants  Research  (DMAPR), Anand, Gujarat, under the Indian Council for Agricultural Research (ICAR), conducts basic, applied and adaptive research on medicinal plants.

The  details  of  ongoing  projects  pertaining  to  medicinal  plants  in  the  different Research  Councils  of  the  Ministry  of  Ayush  and  other  Ministries  throughout  the  country, including North West Bengal, are appended in Annexure-III.

In addition, the National Medicinal Plants Board (NMPB), Ministry of Ayush, under its Central Sector Scheme (CSS) on 'Conservation, Development and Sustainable Management  of  Medicinal  Plants'  provides  project-based  financial  support  to  carry  out research activities on various aspects of medicinal plants to Government as well as private universities/research  institutions/organizations  across  the  country.  Details  of  the  ongoing projects  supported  throughout  the  country,  including  North  West  Bengal,  are  appended  in Annexure IV.

Ans.  (c): Yes  Sir,  the  Central  Council  for  Research  in  Unani  Medicine  (CCRUM)  and Central Council for Research in Siddha (CCRS) under the Ministry of Ayush has conducted a series  of  surveys  regarding  the  availability  of  medicinal  plants  in  the  Kolli  Hills  region  of Namakkal district of Tamil Nadu. The details of the  area surveyed in the Kolli Hills region of Namakkal district are appended in Annexure-V

Ans.  (d): No  Sir,  however  presently,  the  NMPB,  Ministry  of  Ayush  has  supported  the Regional  Raw  Drug  Repository  (RRDR-Southern  Plateau  Region)  in  respect  of  raw  drugs being used in the ASU&H systems of medicine under the Central Sector Scheme at National Institute  of  Siddha  (NIS),  Chennai  as  lead  institute  along  with  Siddha  Central  Research Institute (SCRI) of Central Council for Research in Siddha (CCRS) and Regional Research Institute  of  Unani  Medicine  (RRIUM),  Chennai  as  other  two  collaborating  Institute.  The repository will serve as a one-stop library for raw drugs available in the Southern part of the country and act as an accredited reference library  (Herbarium, Raw Drug Museum etc.) to authenticate raw drugs.

## Annexure-I

## A. State / UT-wise details of Research Institute / Centre / Unit under Central Council for Research in Ayurvedic Sciences (CCRAS) involved in medicinal plant research:

|   S.No. | State/UT                 | Name of Institute/Centre                                               |
|---------|--------------------------|------------------------------------------------------------------------|
|       1 | Andaman &Nicobar Islands | Regional Ayurveda Research Institute, Port Blair.                      |
|       2 | Arunachal Pradesh        | Regional Ayurveda Research Institute, Itanagar.                        |
|       3 | Assam                    | Central Ayurveda Research Institute, Guwahati.                         |
|       4 | Himachal Pradesh         | Regional Ayurveda Research Institute, Mandi.                           |
|       5 | Jammu &Kashmir           | Regional Ayurveda Research Institute, Jammu.                           |
|       6 | Karnataka                | Central Ayurveda Research Institute, Bengaluru.                        |
|       7 | Kerala                   | National Ayurveda Research Institute for Panchakarma, Cheruthuruthy.   |
|       7 | Kerala                   | Regional Ayurveda Research Institute, Thiruvananthapuram               |
|       8 | Madhya Pradesh           | Regional Ayurveda Research Institute, Gwalior.                         |
|       9 | Maharastra               | Regional Ayurveda Research Institute, Pune.                            |
|      10 | Nagaland                 | Regional Ayurveda Research Centre, Dimapur, Nagaland.                  |
|      11 | Punjab                   | Central Ayurveda Research Institute, Patiala.                          |
|      12 | Rajasthan                | M.S. Regional Ayurveda Research Institute, Jaipur.                     |
|      13 | Sikkim                   | Regional Ayurveda Research Institute, Gangtok.                         |
|      14 | Tamil Nadu               | Captain Srinivasa Murthy Central Ayurveda Research Institute, Chennai. |
|      15 | Telangana                | National Centre of Indian Medical Heritage, Hyderabad.                 |
|      16 | Uttar Pradesh            | Central Ayurveda Research Institute, Jhansi.                           |
|      17 | Uttarakhand              | Regional Ayurveda Research Institute, Ranikhet.                        |
|      18 | West Bengal              | Central Ayurveda Research Institute, Kolkata.                          |

## B. State / UT-wise details of Research Institute / Centre / Unit under Central Council for Research in Unani Medicine (CCRUM) involved in medicinal plant research:

|   S. No. | State/UT            | Name and address of the Institute                                            |
|----------|---------------------|------------------------------------------------------------------------------|
|        1 | Jammu& Kashmir (UT) | Regional Research Institute of Unani Medicine, Srinagar.                     |
|        2 | Odisha              | Regional Research Institute of Unani Medicine, Bhadrak.                      |
|        3 | Tamil Nadu          | Regional Research Institute of Unani Medicine, Chennai.                      |
|        4 | Telangana           | National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. |
|        5 | Uttar Pradesh       | Regional Research Institute of Unani Medicine, Aligarh.                      |
|        6 | West Bengal         | Regional Research Institute of Unani Medicine, Howrah.                       |

## C. State / UT-wise details of Research Institute / Centre / Unit under Central Council for Research in Homoeopathy (CCRH) involved in medicinal plant research:

|   S. No. | State/UT      | Name of the Institute                                                      |
|----------|---------------|----------------------------------------------------------------------------|
|        1 | Tamil Nadu    | Centre of Medicinal Plants Research in Homoeopathy, Ooty .                 |
|        2 | West Bengal   | Dr. Anjali Chatterjee Regional Research Institute of Homoeopathy, Kolkata. |
|        3 | Uttar Pradesh | Dr. D.P. Rastogi Central Research Institute of Homoeopathy, Noida.         |

## D.  State  /  UT-wise  details  of  the  Research  Institute  /  Centre  /  Unit  under  Central Council for Research in Siddha (CCRS) involved in medicinal plant research:

|   S. No. | State/UT   | Name of the Institute                                          |
|----------|------------|----------------------------------------------------------------|
|        1 | Tamil Nadu | 1. Siddha Medicinal Plants Garden (SMPG) at Mettur Dam, Salem. |
|        1 | Tamil Nadu | 2. Siddha Central Research Institute, Chennai.                 |
|        2 | Kerala     | 3. Siddha Regional Research Institute, Thiruvananthapuram.     |

## E.  State  /  UT-wise  details  of  the  Autonomous  National  Research  Institute  under  the Ministry of Ayush, Government of India involved in medicinal plant research:

|   S. No. | State/UT          | Name of the Institute                                                             |
|----------|-------------------|-----------------------------------------------------------------------------------|
|        1 | Arunachal Pradesh | North Eastern Institute of Ayurveda & Folk Medicine Research (NEIAFMR), Pasighat. |
|        2 | Ladakh            | National Institute of Sowa Rigpa (NISR), Leh.                                     |

## Annexure-II

## A.  State  /  UT-wise  details  of  Research  Institute  /  Centre  /  Unit  under  Council  of Scientific & Industrial Research (CSIR) involved in medicinal plant research:

|   Sr. No | State/ UT        | Name of the Institute                                                                                                                                |
|----------|------------------|------------------------------------------------------------------------------------------------------------------------------------------------------|
|        1 | Assam            | Council of Scientific and Industrial Research (CSIR) - North East Institute of Science and Technology (NEIST), Jorhat.                               |
|        2 | Himachal Pradesh | Council of Scientific and Industrial Research (CSIR)-Institute of Himalayan Bioresource Technology (IHBT), Palampur.                                 |
|        3 | Jammu & Kashmir  | Council of Scientific and Industrial Research (CSIR)-Indian Institute Of Integrative Medicine (IIIM), Jammu.                                         |
|        4 | Uttar Pradesh    | Council of Scientific and Industrial Research (CSIR)-Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow.                            |
|        5 | Andhra Pradesh   | Council of Scientific and Industrial Research (CSIR)-Central Institute of Medicinal and Aromatic Plants (CIMAP) research centres, Hyderabad.         |
|        6 | Karnataka        | Council of Scientific and Industrial Research (CSIR)-Central Institute of Medicinal and Aromatic Plants (CIMAP) research centres, Bangalore.         |
|        7 | Uttrakhand       | Council of Scientific and Industrial Research (CSIR)-Central Institute of Medicinal and Aromatic Plants (CIMAP) research centres, Pantnagar &Purara. |

## Annexure-III

A. Details of ongoing projects pertaining to medicinal plants research conducting at the peripheral  Institute  under  the  Central  Council  for  Research  in  Ayurvedic  Sciences (CCRAS), Ministry of Ayush, Government of India, throughout the country, including North West Bengal:

|   S. NO | Name of the State/UT   | Name of the Ongoing Project                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
|---------|------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|       1 | West Bengal            | 1. Optimization of extraction process for the enrichment of extract with selected markers of some important Ayurvedic plants at CARI, Kolkata. 2. Pharmacognostical and chemical profiling of selected Indian medicinal flowers at RARI, Jammu &CARI, Kolkata. 3. Digitalization and indexing of herbarium sheets at CARI Kolkata collected from 1970-2000, CARI, Kolkata. 4. Comparative pharmacognostical and phytochemical standardization of commonly adulterating Ayurvedic drugs and adulterants CARI, Kolkata. 5. Development of Quality Standards of Selected Extra- pharmacopoeial Drugs (Anukta Dravyas) Used in Local Health Traditions Collected from Different Regions of India. CARI, Kolkata. |
|       2 | Uttar Pradesh          | 1. Anthology of Survey Research Outcome from Medico Ethno Botanical Survey (MEBS), CARI, Jhansi 2. Plant Diversity Database of Selected Ayurvedic Medicinal Plant Species from Medicinal Plants Garden of RARI, Pune, JNU, CARI, Jhansi. 3. Characterization of important Ayurvedic medicinal plants through DNA barcoding. CARI Jhansi, CARI, New Delhi. 4. Identification of adulterants/substitutes for Ayurveda plant raw material in trade using pharmacognostic and phytochemical parameters. CARI, Jhansi and NBRI, Lucknow. 5. A comparative study on hydroponic and field cultivated medicinal plants used in Ayurveda. CARI, Jhansi and BHU, Varanasi.                                             |
|       3 | Maharashtra            | 1. Development of Quality Standards of Selected Extra- pharmacopoeial Drugs (Anukta Dravyas) Used in Local Health Traditions Collected from Different Regions of India. RARI, Pune. 2. Mass Cultivation of Selected Economically Important Medicinal Plants at RARI, Pune. 3. Investigating the Effect of Vesicular Arbuscular Mycorrhiza (VAM) on Growth, Yield, Phytochemical Contents and                                                                                                                                                                                                                                                                                                                 |

|    |                   | Pharmacological Activities of Shalaparni and Prishniparni. RARI Pune. 4. Establishment of In vitro propagation protocol for the conservation of Hydnocarpus pentandrus (Buch.-Ham.) Oken, a Vulnerable medicinal plant used in Ayurvedic formulations, RARI, Pune. 5. Developing image-based taxonomical database of plants used in the Ayurveda. RARI, Pune.                                                                                                                                                                                                           |
|----|-------------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|  4 | Tamil Nadu        | 1. Developing Quality Standards for Selected Extra-pharmacopoeial Drugs Collected from Irula tribes of Thandarai, Kancheepuram District, Tamil Nadu. 2. Development and Digitalization of Authentic Ayurvedic Raw Drugs and Herbarium for the Medicinal Plants Appearing in Ayurvedic Formularies of India in Mandatory Drug Testing Laboratories of CCRAS, CSMCARI, Chennai. 3. Development of Quality Standards of Selected Extra Pharmacopoeial ( Anukta Dravya ) Drugs Used in Local Health Traditions collected from different regions of India. CSMCARI, Chennai. |
|  5 | Arunachal Pradesh | 1. Documentation of wild edible and medicinal plants commercialized at local market in Papum Pare and lower Lower Subansiri district of Arunachal Pradesh. RARI Itanagar.                                                                                                                                                                                                                                                                                                                                                                                               |
|  6 | Uttarakhand       | 1. Anthology of Survey Research outcomes from Medico-Ethno Botanical Survey (MEBS), RARI, Ranikhet (Uttarakhand). 2. Mass cultivation of the selected economically important medicinal plants at RARI, Ranikhet.                                                                                                                                                                                                                                                                                                                                                        |
|  7 | Himachal Pradesh  | 1. Documentation and Validation of Local Health Traditions and Ethno-Medicinal Practices in Lahul and Spiti district of Himachal Pradesh. RARI, Mandi.                                                                                                                                                                                                                                                                                                                                                                                                                  |
|  8 | Madhya Pradesh    | 1. Development Of Quality Standards of Selected Extra- Pharmacopoeial Drugs (AnuktDravyas) Used in Local Health Traditions Collected from Different Regions of India. RARI, Gwalior. 2. Macroscopic and microscopic atlas preparation for Ayurvedic Pharmacopeia of India Part -I, Vol-IV. RARI, Gwalior. 3. Development of Quality Standards for Useful Parts of Selected Medicinal Plants of Ayurveda. RARI, Gwalior.                                                                                                                                                 |
|  9 | Sikkim            | 1. Medico Ethno Botanical Survey in the forest areas of Darjeeling district of West Bengal'. RARI, Gangtok                                                                                                                                                                                                                                                                                                                                                                                                                                                              |
| 10 | Telangana         | 2. Comprehensive inventory of local health traditions (LHTS) & ethno medicinal practices (EMPS) in INDIA - validation through ayurvedic and ethnomedicinal literature to establish uniqueness. NIIMH, Hyderabad.                                                                                                                                                                                                                                                                                                                                                        |

|   11. | Jammu                     | 1. Documentation and Validation of Local Health Traditions and Ethno medicinal practices in Sunderbani block of District Rajouri, Jammu and Kashmir. RARI Jammu.                                                                                                                                                                                                                                                                                                                                                                                                                                     |
|-------|---------------------------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    12 | New Delhi                 | 1. Anthology of pharmacognostical research outcomes of CCRAS on selected medicinal plants used in the Ayurveda at CCRAS hqrs, New Delhi.                                                                                                                                                                                                                                                                                                                                                                                                                                                             |
|    13 | Karnataka                 | 1. Comparative evaluation of field and hydroponic cultivation of selected Ayurvedic medicinal plants. CARI, Bengaluru and IIHR, Bengaluru. 2. Study of seasonal variation on bioactive compounds of Panchavalkal-05 medicinal plants used in Ayurveda. CARI, Bengaluru and UAS-B, GKVK. 3. Documentation of Traditional Food Recipes of Karnataka and their Validation with Ayurveda and Nutritional Perspective, TDU, University; CARI, Bengaluru. 4. Formulation and product development of Ayurveda recipes and nutritional evaluation of selected products, CSIR-CFTRI, Mysuru; CARI, Bengaluru. |
|    14 | Kerala                    | 1. In vitro propagation and genetic stability studies of Ipomoea mauritiana Jacq. -a Rare medicinal plant. NARIP, Cheruthuruthy and SNGS College, Pattambi.                                                                                                                                                                                                                                                                                                                                                                                                                                          |
|    15 | Andaman & Nicobar Islands | 2. Standardization the cultivation and seed germination conditions of Centratherum anthelminticum (L.) Kuntze. RARI, Port Blair; ICAR-CIARI, Port Blair.                                                                                                                                                                                                                                                                                                                                                                                                                                             |

## B. Details of ongoing projects pertaining to medicinal plants conducting by peripheral institutes  /  units  of  Central  Council  for  Research  in  Siddha  (CCRS),  Chennai,  Tamil Nadu:

|   Sr No | Name of the State/UT   | Project Tittle                                                                                                                                                       |
|---------|------------------------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|       1 | Tamil Nadu             | Isolation of chemical marker from selected plants used in Reproductive and Child Health.                                                                             |
|       2 | -Do-                   | Analysis of inorganic composition of selected plants used in Siddha system.                                                                                          |
|       3 | -Do-                   | Metabolomic profiling and Identification of Principle Components from herbals used in Siddha System for Cognitive disorders using multivariate statistical analysis. |
|       4 | -Do-                   | Development of DNA based markers for some substitute / adulterant / controversial Siddha medicinal plants                                                            |
|       5 | -Do-                   | Pharmacognostic exploration of under explored medicinal plants of Tamilnadu.                                                                                         |
|       6 | -Do-                   | Preparation of Monographs for some least studied/extra- pharmacopoeial medicinal plants in Siddha system of medicine.                                                |
|       7 | -Do-                   | Survey on the traditional and common uses of medicinal plants from                                                                                                   |

|    |      | Dharmapuri District, Tamil Nadu.                                                                                                  |
|----|------|-----------------------------------------------------------------------------------------------------------------------------------|
|  8 | -Do- | Qualitative and quantitative analysis of Lead in 'Lead containing Plants'- a scientific validation of Siddha Claim.               |
|  9 | -Do- | Qualitative and Quantitative Analysis of Chembu (copper) in 'Chembu containing Plants' - A Scientific validation of Siddha claim. |

## C. Details of ongoing projects pertaining to medicinal plants conducted by peripheral institutes/units of the Department of Biotechnology, Ministry of Science and Technology:

|   S. No. | Name of the Supported Institutions                                                                                                                   | Title of the Project                                                                                                                                                                      |
|----------|------------------------------------------------------------------------------------------------------------------------------------------------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|        1 |  Fragrance and Flavour Development centre (FFDC), Kannauj, U.P  Rama Devi Womens University, Odisha.  Siksha 'O' Anusandhan, Bhubaneswar, Odisha. | Propagation of Elite Kewda ( Pandanus fascicularis ) in association with other Aromatic crops to enhance farmer's income through high quality oil production.                             |
|        2 |  National Institute of Pharmaceutical Education and research (NIPER)- Guwahati, Assam.                                                              | Establishment of GMP accredited Pilot Scale extraction facilities for development of Herbal or phytopharmaceutical products from the Medicinal Plants of NE India.                        |
|        3 |  GLA University, Mathura, U.P.                                                                                                                      | Development of nutraceutical feed additive using medicinal plants ( Moringa oligofiera and Chenopodium album ) against mycobacterial infections in domestic livestock.                    |
|        4 |  National Institute of Technology, Rourkela, Odisha.                                                                                                | Screening and identification of canonical mitophagy inducing phytochemicals from Bacopa monnieri to target NLRP3 inflammasome activation for oral cancer therapeutics.                    |
|        5 |  CSIR- Central Drug Research Institute, Lucknow, UP.                                                                                                | Phytopharmaceutical development of a standardized fraction from the root of Desmodium gangeticum for the treatment of chronic kidney disease-induced skeletal and vascular complications. |
|        6 |  National Institute of Animal Biotechnology, Hyderabad, Telangana  Birla Institute of Technology & Science, Pilani, Hyderabad, Telangana.          | Extraction and evaluation of small molecules from medicinal plants with therapeutic potential against theileriosis.                                                                       |

|   7. |  Birla Institute of Technology & Science, Pilani, Hyderabad, Telangana.  Institute of Medical Sciences, BHU, Varanasi, Uttar Pradesh.                                                       | Molecular studies on Bacopa monnieri to evaluate the modulation of neuronal receptors for schizophrenia using cell based and mouse models.                                                             |
|------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    8 |  CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh.                                                                                                                               | Preclinical Development of a natural molecule (N-012- 0006) from Crotalaria juncea for the management of diabetic nephropathy.                                                                         |
|    9 |  Institute of Advanced Virology, Kerala.                                                                                                                                                     | Development of a rapid and reliable in vitro screening platform based on fluorescent reporter knock-in targeting host cell IFITM gene to identify phytochemical immunomodulators against Dengue virus. |
|   10 |  Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology, Bhubaneshwar  School of Biotechnology, Kalinga Institute of Industrial Technology, Bhubaneshwar, Odisha. | Development of first ever Zingibain containing muco- adhesive buccal patch for management of Oral Submucous Fibrosis.                                                                                  |
|   11 |  Aligarh Muslim University, Aligarh, Uttar Pradesh.                                                                                                                                          | Biotechnological interventions for conservation and phytochemical characterization of Saraca asoca : a venerable medicinal tree.                                                                       |
|   12 |  SRM University, Kattankulathur, Chennai, Tamil Nadu.                                                                                                                                        | Evaluation of antidiabetic nephropathy activity of natural products Withaferin A, limonoids and their analogs from Withania somnifera and Azadirachta indica using in vitro and in vivo models.        |

## Annexure-IV

## Details of ongoing projects supported by the National Medicinal Plants Board (NMPB), Ministry of Ayush, under its Central Sector Scheme on Conservation, Development and Sustainable Management of Medicinal Plants on medicinal plants research throughout the country, including West Bengal:

|   S.No. | State                                                    | Project Title and Organization Details                                                                                                                                                                                                                                                                                                                                                                                                                                                                        |
|---------|----------------------------------------------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|       1 | Assam Arunachal Pradesh Itanagar Nagaland Tripura Sikkim | 1. Critical appraisal and validation of Local Health Traditions (LHTs), Oral Health Traditions (OHTs) and Ethno Medicinal Practices (EMPs): An inclusive study among Ethnic communities of Northeast India. Central Ayurveda Research Institute (CARI), Guwahati, Assam Regional Ayurveda Research Institute, Itanagar. Arunachal Pradesh. Regional Ayurveda Research Institute, Gangtok, Sikkim. Regional Ayurveda Research Centre, Dimapur, Nagaland. Regional Ayurveda Research Centre, Agartala, Tripura. |
|       1 | Assam Arunachal Pradesh Itanagar Nagaland Tripura Sikkim | 2. DNA barcoding of select plants of Assam used in Ayurveda and tradtional medicine along with adulterant detection in marketed Ayurvedic products. Department of Life Sciences, Dibrugarh University, Assam.                                                                                                                                                                                                                                                                                                 |
|       1 | Assam Arunachal Pradesh Itanagar Nagaland Tripura Sikkim | 3. Bio evaluation, identification, quantification of bio active compounds and development of bio-pesticides from ethno- medicinal plant extracts against major insect pest of vegetable crops. Assam Agricultural University, Assam                                                                                                                                                                                                                                                                           |
|       1 | Assam Arunachal Pradesh Itanagar Nagaland Tripura Sikkim | 4. Development of high yielding varieties, phytochemical analysis and bioactivity of Kaempferia parviflora wall. Ex baker: a high value endangered medicinal plant of North East India. CSIR-North East Institute of Science and Technology , CSIR- NEIST                                                                                                                                                                                                                                                     |
|       2 | Chandigarh                                               | 5. Evaluation of suitable microclimatic conditions for certain MAP's by qualitative and quantitative chemical analysis with special reference to secondary metabolites. ICAR- Indian Institute of Soil and Water Conservation ( IISWC), Chandigarh. Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh.                                                                                                                                                                           |

|   3. | Delhi            | 6. Spatial Niche Modelling and Genetic Diversity analysis of Desmodium gangeticum: An Important Medicinal Species of Shivalik Himalayas. The Energy and Resources Institute (TERI), TERI, Delhi Forest Research Institute, Dehradun, Uttarakhand. 7. Bioassay guided fractionation of Acacia catechu and Rhodiola imbricata for the inhibition of PEPCK gene expression and gluconeogenesis in H4IIE hepatoma cell line. National Forensic Sciences University (An Institute of National   |
|------|------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    4 | Gujarat          | 8. Credentials of region-specific selected medicinal herbs that have a specific geographical origin to ensure sustainable supply of quality raw herbal drugs ICAR - Directorate of Medicinal & Aromatic Plants Research, Anand.                                                                                                                                                                                                                                                            |
|    5 | Himachal Pradesh | 9. In vivo and In vitro study on synergistic effect of medicinal plants in breast cancer of mice. Central University of Himachal Pradesh, Kangra, Himachal Pradesh .                                                                                                                                                                                                                                                                                                                       |
|    5 | Himachal Pradesh | 10. Development of Chemometric Database: A Futuristic Approach for the Quality Assurance of Commercially Important Himalayan Medicinal Plants CSIR-Institute of Himalayan Bioresource Technology, Palampur. 11. Collection, Conservation and Characterization of Fritillaria                                                                                                                                                                                                               |
|    6 | Jammu& Kashmir   | 12. 'Conservation, Bioprospection and Development of good agricultural practices for Rheum emodi, Sassurea costus, Podophyllum hexandrum and Aconitum heterophyllum for Ex situ cultivation in Jammu and Kashmir. CSIR-Indian Institute of Integrative Medicine, Sanatnagar, Srinagar.                                                                                                                                                                                                     |
|    6 | Jammu& Kashmir   | 13. Development of Microbial Consortia for Improving Growth and Active Components in Bacopa monnieri (L.)                                                                                                                                                                                                                                                                                                                                                                                  |

|    |                | University of Kashmir, Srinagar.                                                                                                                                                                                                                                                                                     |
|----|----------------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|  7 | Karnataka      | 14. Intercropping of medicinal crops in Coffee plantation in high altitude zone of Karnataka. Indian Institute of Horticultural Research, Hessaraghatta, Bangalore.                                                                                                                                                  |
|  7 | Karnataka      | 15. Genetic enhancement and post-harvest studies in Bacopa monnieri. Indian Institute of Horticultural Research, Hessaraghatta, Bangalore.                                                                                                                                                                           |
|  7 | Karnataka      | 16. Pre and post-harvest enhancement of secondary metabolites in Withania somnifera by adopting patented process and technology transfer. Padmashree Institute of Management and Sciences, Kengeri.                                                                                                                  |
|  7 | Karnataka      | 17. Medicinal plants-based Ecorestoration of Coffee Plantations in Hassan and Chickmagalur Districts of Western Ghats. Institute of Wood Science and Technology, Bangalore .                                                                                                                                         |
|  8 | Kerala         | 18. Exploring the ayurveda concept of controversial drug (Sandigdha Dravya) by pharmacognostical, phytochemical and DNA barcoding of source plants of ayurvedic drug 'Murva'                                                                                                                                         |
|  8 | Kerala         | Vaidyaratnam Ayurveda College, Ollur, Kerala. 19. Identification of substitute /sustainable alternative species or plant part for selected rare medicinal plants by phytochemical and pharmacological evaluation Arya Vaidya Sala, Kottakkal, Malappuram 20. Preparation of a Monograph on Selected Medicinal Plants |
|  8 | Kerala         | Used as Substitutes/Adulterants in Ayurveda with Special Reference to Mesua ferrea L.: An Integrated Pharmacognostic, Phytochemical, and Pharmacological Approach Jawaharlal Nehru Tropical Botanic Garden & Research Institute, Palode, Thiruvananthapuram,                                                         |
|  9 | Madhya Pradesh | 21. Germplasm collection and bio-molecular characterization Black Turmeric ( Curcuma caesia Roxb.). Jawaharlal Nehru Krishi Vishwa Vidhalya, Jabalpur.                                                                                                                                                               |

|   10. | Maharashtra   | 22. Substitution of Root/Barks with leaves of Medicinal Plants, a Strategic method for conservation of some medicinal plants from Vidarbha region". Rashtrasant Tukadoji Maharaj Nagpur, University, Nagpur                                                                                             |
|-------|---------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    11 | Odisha        | 23. Harnessing the potential of endophytes of Piper longum as an alternate source for piperine production: optimization of protocol for laboratory production and exploration of its anticancer properties. Regional Plant Resource Centre, Bhubaneswar                                                 |
|    11 | Odisha        | 24. Chemotyping and genotyping of Embelia ribes Brum F. for authentic identification, selection and conservation of elites. Centurion University of Technology and Management, Bhubaneswar.                                                                                                             |
|    12 | Rajasthan     | 25. Exploration and Documentation of Ethno-medicinal Practices of Rural and Tribal Population of Rajasthan. JyotiVidyapeeth Women's University, Jaipur                                                                                                                                                  |
|    13 | Tamil Nadu    | 26. Development of microbial consortia to mitigate the soil-borne pathogens problem in Glorylily. Tamil Nadu Agricultural University, Coimbatore 27. Quantitative documentation of medicines used in Varmam therapeutics by the non institutionally trained Siddha Practitioners of Southern Tamil Nadu |
|    13 | Tamil Nadu    | St Xavier's College, Palayamkottai, Tirunelveli                                                                                                                                                                                                                                                         |
|    13 | Tamil Nadu    | 28. Deciphering the response of Ficus fruit polysaccharides on Major Histocompatibility Complex (MHC) in Inflammatory Bowel Disease (IBD). Bharathiar University, Coimbatore                                                                                                                            |
|    13 | Tamil Nadu    | 29. Green nanopriming technology based efficient in vitro and in vivo seed germination of Saraca asoca (Roxb.) De Wilde; an endangered medicinal plant . Bharathiar University, Coimbatore                                                                                                              |
|    13 | Tamil Nadu    | 30. Studies on Reassessment of Population, Reproductive Biology and Restoration of Six Endemic and Endangered Species of Cinnamomum from the Western Ghats. The Gandhigram Rural Institute (Deemed To Be University), Dindigul.                                                                         |

|   14. | Telangana     | 31. Isolation and evaluation of Bioactive Components of Young Roots and Leaf Extracts of Bilva for IL-2 Immunotherapy: In Vitro and In Vivo Studies. University of Hyderabad, Gachibowli, Hyderabad.                                                                                                        |
|-------|---------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|    15 | Uttar Pradesh | 32. In vitro regeneration of multipurpose and medicinally important Butea monosperma Lam. and its assessment for mass propagation of genetically uniform quality planting material ICAR-Central Agroforestry Research Institute (CAFRI), Jhansi.                                                            |
|    15 | Uttar Pradesh | 33. Morpho-anatomical and quality attributes characterization in Sida cordifolia L . For high root biomass yielding genotypes Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow. 34. Isolation, characterization of herbal plant constituents and their                                   |
|    15 | Uttar Pradesh | effect on curing Osteoporosis using osteoblastic cell lines. Sharda University, Greater Noida.                                                                                                                                                                                                              |
|    16 | Uttarakhand   | 36. Phytochemical, morphological and molecular evaluation of RET medicinal plant Trillium govanianum (Nag chhatri) distributed in Northwestern Himalayan Region for its Conservation and Utilization. Forest Research Institute, Dehradun. 37. Bio prospecting of Lindera pulcherrima by chemoprofiling and |
|    16 | Uttarakhand   | Forest Research Institute, Dehradun. 38. Field genebank: a sustainable tool for conservation of some threatened high altitude medicinal plant species. High Altitude Plant Physiology Research Centre (HAPPRC), HNBGU, Srinagar.                                                                            |
|    17 | West Bengal   | 39. Chemotyping, quality assessment, in vitro propagation of Indian olibanum ( Boswellia serrata Roxb.) from Eastern part of India and their plantation in a new area Ramakrishna Mission Vivekananda Centenary College, Rahara, Kolkata.                                                                   |

Annexure-V A. Details of survey by the Central Council for Research in Unani Medicine (CCRUM)

## has been conducted in the Kolli Hills region of Namakkal district of Tamil Nadu:

|   S.No | Year     | Name of the Forest Divisions   | Name of the Forest Areas                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |   Number of plant species collected and documented |
|--------|----------|--------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|----------------------------------------------------|
|      1 | 2012- 13 | Namakkal                       | Bailnadu RF, Ariyur RF, Ariyurkusba, Kulivalavu RF, Karumbur RF, Puranikadu RF, Ariyursolai lower slope, Puliyansolai, Vazhavanthinadu RF, Valapurnadu RF, Azhakadu RF, Sellurnadu RF, Veeraganurpatti RF, Semmedu RF, Karavalli RF. Athanur RF, Pazhanthinipatti RF, Puthupatti RF, Mathimaduvu Dam RF, Oathakadai RF, Wayalnadu RF. Palliparai RF, Puthupatti RF, Maval RF, Adukam RF, Perumalmalai RF, Velikattupatti RF, Seradi RF, Adukamparai RF. Puliyansolai RF, Erumaipatti RF, Nadukombai RF and Karavalli RF. |                                                201 |
|      2 | 2015- 16 | Namakkal                       | Podimattu, Viripara, Letchmi, Rajamalai, Pattimudi, Eravikulam National Park, Perumalkoil, Naikankombai, Pallaniyappar Koil, Mathimaduvu, Karavalli, Nadukombai, Ariyur, Nadukombai, Vazhavanthinadu, Karuvalli, Bailnadu, Puliyansolai, Karavalli upper slopes and Kollimalai lower slopes.                                                                                                                                                                                                                             |                                                 86 |
|      3 | 2020- 21 | Namakkal,                      | Ariyursholai, Ariyursholai Kasba, Ariyurnadu, Panamarattupatti, Semedu, Karavalli, Nathakkadu. Masi Periyanna Temple hills, Thathan Kombai (MPCA), Kolli hills, Lower slope, Sakkaraipatti Forest area. Puliyansholai, Periyasami koil, Pasilaikombai, Kullathu kombai. Nadukombai, Palliparai.                                                                                                                                                                                                                          |                                                156 |

## B. Details of the survey by the Central Council for Research in Siddha (CCRS) has been conducted in the Kolli Hills region of Tamil Nadu:

|   S. No |   Year | Locality                          |   Number of plant species collected and documented |
|---------|--------|-----------------------------------|----------------------------------------------------|
|       1 |   2022 | Kollimalai, Cholakkadu (Adivaram) |                                                 55 |