Lok Sabha Question No. 3260 (UNSTARRED), answered on 2021-12-17
Subject: Treatment of Epilepsy
Ministry: HEALTH AND FAMILY WELFARE
Asked by: Queen Oja, Vishnu Dutt Sharma, Arvind Kumar Sharma, Bharatiben Dhirubhai Shyal

## GOVERNMENT OF INDIA

## MINISTRY OF HEALTH AND FAMILY WELFARE DEPARTMENT OF HEALTH RESEARCH

## LOK SABHA UNSTARRED QUESTION NO. 3260

## TO BE ANSWERED ON 17 th  DECEMBER, 2021

## TREATMENT OF EPILEPSY

## 3260.   SHRIMATI QUEEN OJA:

SHRI VISHNU DATT SHARMA:

DR. ARVIND KUMAR SHARMA:

DR. BHARATIBEN DHIRUBHAI SHIYAL:

Will the Minister of HEALTH AND FAMILY WELFARE be pleased to state:

- (a) whether the Government proposes to promote dedicated research and development for the treatment  and  other  medical  aspects  of  Epilepsy,  the  fourth  most  common  neurological
- disorder in India;
- (b) if so, the details thereof; and
- (c) if not, the reasons therefor?

## THE MINISTER OF STATE FOR HEALTH AND FAMILY WELFARE

## ANSWER DR. BHARATI PRAVIN PAWAR

- (a)  to  (c): Government  of  India  provides  funds  for  Research  and  developing  treatment  of Epilepsy. The details of projects by various organisations are given in Annexure.

## Annexure

|   SI. No. | Funding Agency                                             | Project period   | Title of the Project                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
|-----------|------------------------------------------------------------|------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|         1 | Indian Council of Medical Research                         | 2021-2022        | Defferential expression of epilepsy-associated long non-coding RNAs (IncRNAs) in Epileptogenic Brain Tissue and peripheral Blood.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |
|         2 | Indian Council of Medical Research                         | 2019-2022        | Awareness of head-injury while driving in patients with epilepsy: A preventive and public education study                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |
|         3 | Indian Council of Medical Research                         | 2021-2024        | "Can capacity building at primary care level improve access to epilepsy care in Chhattisgarh? An Implementation Research"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |
|         4 | Indian Council of Medical Research                         |                  | Towards developing a National Epilepsy Control Program: A Pilot community - Based, Randomized Trial of Delivery of Care to People with Epilepsy.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      |
|         5 | Department of Biotechnology                                | 2018-2022        | Elucidating region specific alterations of glutamatergic excitatory neurotransmission in a rodent pilocarpine model of temporal lobe epilepsy.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        |
|         6 | Biotechnology Industry Research Assistance Council (BIRAC) | 2019-2020        | A Portable, Affordable & Accessible Diagnostic Tool for Mental Health Conditions including Seizures and Epilepsy                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      |
|         7 | O/o the Principal Scientific Adviser, GoI                  | 2018-2022        | Investigation of the role of dysfunctional benzodiazepine hinding site on GABA A receptor in benzodiazepine-resistance associated with drug-resistant epilepsy                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        |
|         8 | Department of Science and Technology                       | 2020-2023        | Elucidating the Efficacy of yoga meditation and its associated epilenetic modulation in person with temporal plus and temporal lobe epilepsy.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
|         9 | Department of Science and Technology                       | 2021-2024        | Association of social cognition and behavioural impairment in persons with epilepsy or antiepileptic drug monotherapy correlation with neuroimaging findings and trace elements status                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                |
|        10 | Department of Science and Technology                       |                  | Various research activities are going on in the Department of Neurology's R. Madhavan Nayar Center for Comprehensive Epilepsy Care (RMNC) in the Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum, under the aegis of Department of Science and Technology, with regard to presurgical evaluation of refractory epilepsy, electrophysiology, neuropsychology, multimodality imaging, electroencephalography functional MRI co-registration (EEG-fMRI), intracranial EEG along with brain mapping evaluation strategies, genetics of complex childhood epilepsies such as developmental-epileptic encephalopathies and the Kerala Registry of Epilepsy and Pregnancy (KREP) to support women with epilepsy. |
|        11 | All India Institute of Medical Sciences, Delhi             | 2019-2020        | Elucidating region specific alterations of glutamatergic excitatory neurotransmission in a rodent pilocarpine model of temporal lobe epilepsy.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        |
|        12 | Board of Research in Nuclear Sciences (BRNS), Mumbai       | 2018-2022        | Effect of plasma jet on tumor tissues resected from patients with tumor linked refractory epilepsy                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    |