Lok Sabha Question No. 3440 (UNSTARRED), answered on 2021-12-17
Subject: Technology of AYUSH-64
Ministry: AYURVEDA,YOGA & NATUROPATHY,UNANI,SIDDHA AND HOMEOPATHY (AYUSH)
Asked by: Suresh Kodikunnil, Bheemrao Baswanthrao Patil, Bhartruhari Mahtab

## GOVERNMENT OF INDIA MINISTRY OF AYUSH

## LOK SABHA UNSTARRED QUESTION NO. 3440 TO BE ANSWERED ON 17 TH  DECEMBER, 2021

## TECHNOLOGY IN AYUSH-64

3440.  SHRI KODIKUNNIL SURESH, SHRI B.B. PATIL, SHRI BHARTRUHARI MAHTAB

Will the Minister of AYUSH be pleased to state:

- (a) whether  the  Central  Council  for  Research  in  Ayurvedic  Sciences  (CCRAS) has transferred the technology of AYUSH-64, a drug used in mild and asymptomatic and mild to moderate cases of COVID-19, to different companies for manufacturing the medicine;
- (b) if so, the details thereof, State/UT-wise;
- (c) whether the Government proposes to promote usage of ayurvedic medications  to  treat  patients  experiencing  COVID  related  medical  conditions  and post COVID ailments, if so, the details thereof;
- (d) whether clinical trials of the said drug conducted by the Government and the Council  of  Scientific  and  Industrial  Research  (CSIR)  has  proved  to  be  effective  in treating COVID-19, if so, the details thereof;
- (e) whether AYUSH-64 administered on patients quarantined at home was found beneficial, if so the details thereof; and
- (f) whether  the  necessary  guidelines  laid  down  in  Drugs  and  Cosmetics  Act, 1940 were complied with in the case of the said drug, if so, the details thereof?

## ANSWER

## THE MINISTER OF AYUSH (SHRI SARBANANDA SONOWAL)

- (a)&(b)  Yes, Sir. The technology for manufacturing AYUSH 64 has been transferred to 46 companies. The details are annexed.
- (c) Government of India has released ' National Clinical Management Protocol based on Ayurveda and Yoga for management of COVID-19'

This  protocol  is  for  management  of  mild  COVID-19.  Moderate  to Severe COVID-19 individuals may have informed choice of treatment options. It  includes  general  &physical  measures,  dietary  measures  and  symptom management for prophylactic care, asymptomatic COVID-19 positive and mild COVID-19 positive along with post-COVID management.

In addition to this, Ministry of Ayush has also issued -

- i. Guidelines for Registered Practitioners of respective system of AYUSH. These guidelines  are  made  available  in  public  domain  for  the  benefit  of  registered AYUSH  practitioners  including  Homoeopathy  to  help  in  the  management  of COVID 19 pandemic uniformly.
- ii. Ayurveda, Unani and Siddha preventive measures for self-care during COVID19  and  Guidelines  for  Ayush  Practitioners  for  COVID-19  Patients  in  Home Isolation.
- iii. Home care guidelines for children and Advisory for AYUSH Practitioners about prophylactic care in Children during the COVID-19 Pandemic.
- iv. Ayush  Recommendations  for  the  public  on  holistic  health  and  well-being Preventive measures and care during COVID-19 and Long COVID-19.
5. (d)&(e)  The Council of Scientific and Industrial Research (CSIR) and the Ministry of AYUSH has conducted clinical trials for AYUSH interventions for COVID-19, that  included  AYUSH-64.  AYUSH-64  was  found  effective  &  safe,  and recommended for mild to moderate COVID-19 patients. The outcome of the study has highlighted that AYUSH 64 has hastened clinical recovery, reduced hospitalization  and  improved  overall  health  in  mild  and moderate COVID-19 when co-administered with standard of care.
6. (f) All  State  Licensing  Authorities  (SLA's)/Drug  Controllers  were  requested  to allow  the  licensed  manufacturers  for  AYUSH-64  under  their  jurisdiction  to include new indication of AYUSH 64 for repurposing as an intervention for the management  of  asymptomatic,  mild  to  moderate  COVID-19  in  addition  to existing indication(s) and also to expedite the process of the licensing/approval  of  such  applications  for  the  manufacturing  of  AYUSH  64 medicine,  provided  the  prescribed  standards  and  relevant  provisions  of  the Drugs & Cosmetics Rules, 1945, are fulfilled.

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ANNEXURE REFERRED IN REPLY TO PART (A & B) OF LOK SABHA UNSTARRED QUESTION  NO.  3440  FOR  ANSWER  OF  17.12.2021  REGARDING  TECHNOLOGY  OF AYUSH-64 -LIST OF MANUFACTURING UNITS TO WHICH AYUSH-64 TECHNOLOGIES HAVE BEEN TRANSFERRED

|   Sl. No. | Name of the Company                                                                                                 | State/UT wise    |
|-----------|---------------------------------------------------------------------------------------------------------------------|------------------|
|         1 | M/s Multani Pharmaceuticals Ltd. , New Delhi.                                                                       | NCT of Delhi     |
|         2 | M/s Mangalam Biotech Research, 39/23, 2nd Floor, Lane No. 15, Sameyapur Industrial Area, Delhi-110042               | NCT of Delhi     |
|         3 | M/s Hamdard Laboratories (India)- Medicine Division, Hamdard Building, 2A/3 Asaf Ali Road, New Delhi-110002         | NCT of Delhi     |
|         4 | M/s Goa Antibiotics &Pharmaceuticals Ltd., Tuem Industrial Area, Tuem, Pernem, Goa-403512                           | Goa              |
|         5 | M/s Nirav Healthcare, Plot No. 25, GIDC Phase-I, Industrial Estate, Rajpipla, Narmada, Gujarat-393145,              | Gujarat          |
|         6 | M/ s Nagarjun Pharmaceuticals Pvt Ltd., Sherisa, Kalol-Khatraj Road, Kalol, Gandhinagar, Ahmedabad, Gujarat- 382721 | Gujarat          |
|         7 | M/s Amulya Labs Private Ltd. , Plot No 74, Industrial Estate HSIIDC, Alipur, Barwala, Panchkula, Haryana- 134118    | Haryana          |
|         8 | M/s North India Life Sciences Private Limited, Plot No-430, Sec-3, HSIIDC Karnal, Haryana- 132001                   | Haryana          |
|         9 | M/s Alna Biotech Pvt. Ltd., SCF 1013, Ground Floor Motor Market, Manimajra, Chandigarh-160101                       | Haryana          |
|        10 | M/s Tirupati Medicare Ltd ., Paonta Sahib, Distt. Sirmour, H.P.                                                     | Himachal Pradesh |
|        11 | M/s Shree Dhanwantri Herbals, Village Kishanpura, Tehsil Nalagarh, District Solan, Himachal Pradesh-174101          | Himachal Pradesh |
|        12 | M/s Baijnath Pharmaceuticals Pvt Ltd., P.O. Paprola, Tehsil Baijnath, Distt. Kangra, Himachal Pradesh-176115        | Himachal Pradesh |
|        13 | M/s Zeon Lifesciences Ltd., Village Kunja, Rampur Road, Paonta Sahib, Himachal Pradesh- 173025                      | Himachal Pradesh |
|        14 | M/s Himalaya Research Laboratory, EPIP, Bari Brahmna, Jammu- 181133                                                 | Jammu& Kashmir   |

|   Sl. No. | Name of the Company                                                                                                                            | State/UT wise   |
|-----------|------------------------------------------------------------------------------------------------------------------------------------------------|-----------------|
|        15 | M/s Sriveda Sattva Private Ltd ., Third Floor, No. 54/46, 39 th A Cross, 11 th Main Road, 4 th T Block, Jayanagar, Bangalore, Karnataka-560041 | Karnataka       |
|        16 | M/s Revinto Life Science Pvt. Ltd, Plot No. 21, KIDAB Industrial Area, Shirwada, Karwar, Uttara Kannada District, Karnataka- 581306            | Karnataka       |
|        17 | M/s Karnataka Antibiotics &Pharmaceuticals Ltd ., Dr. Rajakumar Road, First Block, Rajajinagar, Bangalore-560010                               | Karnataka       |
|        18 | M/s S.D.P. Remedies and Research Centre , Business Office at Udayagiri, Korungu, Kemminje, Village Puttur, DK, Karnataka- 574202               | Karnataka       |
|        19 | M/s Dhathri Ayurveda Pvt. Ltd ., 33/1882B, Adappilly Road, Ernakulum, Kerala                                                                   | Kerala          |
|        20 | M/s Pharmaceutical Corporation (IM) Kerala Ltd., Kuttanellur P.O., Trissur, Kerala-680014                                                      | Kerala          |
|        21 | M/s HLL Lifecare Limited, HLL Bhavan, Mahilamandiram Road, Poojappura, Thiruvananthapuram, Kerala- 695012                                      | Kerala          |
|        22 | M/s Bipha Drug Laboratories Private Ltd . XIII/804, Pallipurathukavu Junction, Kottayam, Kerala- 686039                                        | Kerala          |
|        23 | M/s Haritha Pharmaceuticals, Building No. 332, Vadakkumuri, Varandarappilly, Thrissur, Kerala- 680303                                          | Kerala          |
|        24 | M/s Jamna Herbal Research Limited , 15, Zone-II, Maharana Pratap Nagar, Bhopal                                                                 | Madhya Pradesh  |
|        25 | M/s Upkaran Pharmaceuticals , Shop No. 25, Board Office Square, Zone-II, Maharana Pratap Nagar, Bhopal, Madhya Pradesh 462011                  | Madhya Pradesh  |
|        26 | M/s Dindayal Industries Ltd. , 5-6, Industrial Estate, Tansen Road, Birla Nagar, Gwalior- 474004, M.P.                                         | Madhya Pradesh  |
|        27 | M/s Minor Forest Produce Processing &Research Centre, Van Parisar, Barkheda, Pathani, Bhopal-462021                                            | Madhya Pradesh  |
|        28 | M/s Dhootpapeshwar Ltd ., Veer Savarkar Chowk, Panvel, Raigad- 410206, Maharashtra                                                             | Maharashtra     |
|        29 | M/s Karnani Pharmaceuticals Pvt Ltd. 19/23, Vithoba Lane, Vithalwadi, Mumbai, Maharashtra- 400002                                              | Maharashtra     |

|   Sl. No. | Name of the Company                                                                                                                 | State/UT wise   |
|-----------|-------------------------------------------------------------------------------------------------------------------------------------|-----------------|
|        30 | M/s OMPharmaceuticals Ltd., 202, Vishwa Nanak Apartments, Gurunanak Wadi, Chakala, Andheri (East), Mumbai, Maharashtra- 400099      |                 |
|        31 | M/s Pharmaveda (India) Private Ltd., B-4 Kamdar Shopping Centre, Opp Railway Station Vile Parle (East), Mumbai, Maharashtra- 400057 |                 |
|        32 | Aayukart Private Ltd. H1-2213, RIICO Industrial Area, Ramchandrapura, Sitapura Extension, Jaipur, Rajasthan- 302022                 | Rajasthan       |
|        33 | M/ s Rajasthan Herbal International Pvt Ltd., F- 143, IInd Phase, Riico Industrial Area, Jhunjhunu, Rajasthan- 333001               | Rajasthan       |
|        34 | M/s Sarvotham Care Limited, 197, Nicholson Road, Tadbund, Secunderabad, Telangana-500009                                            | Telangana       |
|        35 | M/s Dabur India Pvt. Ltd., Sahibabad, Ghaziabad                                                                                     |                 |
|        36 | M/s Indian Medicines Pharmaceuticals Co. Ltd. (IMPCL), Mohan, Ramnagar, Distt. Almora                                               |                 |
|        37 | M/s Uttarakhand State Medicine& Pharmaceuticals Ltd., Haldwani, U.K.                                                                |                 |
|        38 | M/s Meghdoot Gramodyog Sewa Sansthan , A1/18, Sector- H, Puraniya Chauraha, Aliganj, Lucknow , U.P.                                 |                 |
|        39 | M/s Uma Ayurvedics Private Ltd ., Madhav Puri, Nadrai Gate, Kasganj (Etah), - 207123, U.P.                                          | Uttar Pradesh   |
|        40 | M/s Basic Ayurveda, 46, Anand Industrial Estate, Mohan Nagar, Ghaziabad- 201007, U.P.                                               |                 |
|        41 | M/s Amar Pharmaceuticals and Labs (India) Pvt. Ltd., 17/110 Nawab Compound,Ram Narain Bazar, Kanpur, Uttar Pradesh-208001           |                 |
|        42 | M/s Royal Bee Natural Products Pvt. Ltd., S-61 Loni Road, Site-2 Mohan Nagar, Ghaziabad- 201007 U.P.                                |                 |
|        43 | M/s Desh Rakshak Aushdhalya Ltd ., Kankhal, Haridwar-249408                                                                         | Uttarakhand     |
|        44 | M/s Maheshwari Pharmaceuticals (India) Ltd. , Plot No. 7, Sector 6B IIE SIDCUL, Haridwar,Uttarakhand-249403                         | Uttarakhand     |
|        45 | M/s Multi State Cooperative Pharmaceuticals &Research, Lane No. 1, Mangal Parao, Haldwani, Nainital -263139, Uttarakhand            | Uttarakhand     |

|   Sl. No. | Name of the Company                                                                          | State/UT wise   |
|-----------|----------------------------------------------------------------------------------------------|-----------------|
|        46 | M/s Co-operative Drug Factory, Udyog Nagar, Ganiadeoli, Ranikhet, Almora, Uttarakhand-263645 |                 |