Lok Sabha Question No. 4285 (UNSTARRED), answered on 2018-03-21
Subject: Traditional Knowledge Digtial Library
Ministry: SCIENCE AND TECHNOLOGY
Asked by: JANARDAN MISHRA

## GOVERNMENT OF INDIA

## MINISTRY OF SCIENCE AND TECHNOLOGY

## DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH LOK SABHA

UNSTARRED QUESTION No. 4285

(TO BE ANSWERED ON 21.03.2018)

## TRADITIONAL KNOWLEDGE DIGITAL LIBRARY

## 4285.   SHRI JANARDAN SINGH SIGRIWAL:

Will the Minister of SCIENCE AND TECHNOLOGY be pleased to state:

- (a) whether  the  Government  has  formulated  any  scheme/plan  for  having public  access  to  the  Traditional  Knowledge  Digital  Library  (TKDL) database;
- (b)
- if so, the details thereof and if not, the reasons therefor;
- (c) the  number  and  details  of  cases  where  the  usage  of  TKDL  database has proved as an effective deterrent against biopiracy and resulted in protection of traditional knowledge; and
- (d) the  number  of  pre-grant  opposition  cases,  filed  by  TKDL,  pending  at various international patent offices?

## ANSWER

## MINISTER OF SCIENCE AND TECHNOLOGY AND EARTH SCIENCES (DR. HARSH VARDHAN)

- (a) No, Madam. At present no scheme/plan has been formulated for having public  access  to  the  Traditional  Knowledge  Digital  Library  (TKDL) database.
- (b) Safeguarding  the  information  present  in  the  TKDL  database  from misappropriation is of paramount importance.
- (c) There  are  220  cases  wherein  patent  applications  have  been  either withdrawn/deemed withdrawn or amended or set aside on the basis of TKDL  evidence  thus  protecting  Indian  traditional  knowledge.  These cases have been at the patent offices of Europe, USA, India, Canada, Australia and United Kingdom. The details of these patent applications are at Annexure-1.
- (d) About 900 submissions as pre-grant oppositions/ third party observations filed by TKDL are pending at patent offices worldwide.

## ANNEXURE-I

| TKDL Outcomes against biopiracy   | TKDL Outcomes against biopiracy   | TKDL Outcomes against biopiracy                                                                                 | TKDL Outcomes against biopiracy                                                                                    | TKDL Outcomes against biopiracy   |
|-----------------------------------|-----------------------------------|-----------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------|-----------------------------------|
| Sr. No.                           | Pub. No.                          | Title                                                                                                           | Applicant                                                                                                          | Date of Filing                    |
| 1                                 | EP1520585                         | Cancer treatment using natural plant products or essential oils or components from some pistacia species.       | Data Medica Padova, SPA, Italy                                                                                     | 24-Sep-04                         |
| 2                                 | EP1747786                         | Natural product in cream with anti- vitiligo therapeutic properties.                                            | Perdix Eurogroup, S.L., Spain                                                                                      | 24-Jul-06                         |
| 3                                 | EP1660007                         | Compositions for Diabetes treatment and Prophylaxis                                                             | Ayurvedic-Life International, LLC, P.O. Box 10, Neenah, WI 54957 / US                                              | 11-Aug-04                         |
| 4                                 | EP2464363                         | Natural extract from whole Banana fruit                                                                         | M/S Medasani, Munisekhar/ India                                                                                    | 11-Aug-10                         |
| 5                                 | EP2435057                         | Compositions and methods for modulating lipid composition                                                       | New Chapter, Inc. / US                                                                                             | 28-May-10                         |
| 6                                 | EP1607006                         | Functional berry composition.                                                                                   | UNILEVER NV, Netherland                                                                                            | 18-Jun-04                         |
| 7                                 | EP2044850                         | Method for altering the metabolism characteristic of food products.                                             | Clara's ApS, Denmark                                                                                               | 19-Sep-07                         |
| 8                                 | EP1889638                         | Medicaments and food for treatment or prevention of obesity and/or diabetes containing cicer arietinum extract. | Jumpsun Bio-Medicine (Shanghai) Co. Ltd, China                                                                     | 6-Mar-06                          |
| 9                                 | EP1750809                         | Citrus Fruit Skin extract for Angiogenesis promotion                                                            | Industrial Research Limited and Otago Innovation Limited / New Zealand                                             | 29-Apr-05                         |
| 10                                | EP1807098                         | Herbal compositions for treatment of diabetes.                                                                  | Amcod Limited, Mombasa, Kenya                                                                                      | 13-Sep-05                         |
| 11                                | EP1967197                         | Use of preparations, purifications and extracts of aloe.                                                        | Cognis IP Management GmbH, Germany                                                                                 | 9-Mar-07                          |
| 12                                | EP2065031                         | Skin treatment composition.                                                                                     | Evonik Goldschmidt GmbH,Germany                                                                                    | 30-Nov-07                         |
| 13                                | EP1906980                         | Method of treatment or managment of Stress.                                                                     | Natreon Inc. 2-D Janine Place New Brunswick, NJ 08901/United States                                                | 27-Jul-06                         |
| 14                                | EP1660106                         | Biotherapetutics for Mitigation of health disorders from Terminalia Arjuna.                                     | Avesthagen Limited Unit 3, Discoverer, 9th Floor International Tech Park Whitefield Road Bangalore 560 066 / India | 15-Aug-03                         |
| 15                                | EP1825845                         | Cosmetic herbal compositions.                                                                                   | Jan Marini Skin Research Inc. 6951 Via del Oro San Jose, California 95119/United States                            | 22-Feb-07                         |

|   16 | EP2015761   | Methods and composition for treating Sore Throat.                                                                                                                                                                | Naveh Pharma (1996) Ltd. P.O. Box 8139 42505 Netanya/Israel2009/04                                                                | 29-Mar-07   |
|------|-------------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------------------------------------------------|-------------|
|   17 | EP1937231   | Pharmaceutical compositions for the treatment of Chronic Obstructive Pulmonary Disease.                                                                                                                          | GW Pharma Limited Porton Down Science Park Salisbury, Wiltshire SP4 OJR/Great Britain                                             | 11-Oct-06   |
|   18 | EP2133089   | Compositions for the treatment of disorders of the upper respiratory tract and influenza syndromes.                                                                                                              | Indena S.p.A. Viale Ortles, 12 20132 Milano / Italy[2009/51]                                                                      | 12-Jun-08   |
|   19 | EP2133080   | Compounds containing equol.                                                                                                                                                                                      | Haelan Schweiz GmbH Schützenstrasse 188808 Pfäffikon Switzerland [2009/51]                                                        | 13-Jun-08   |
|   20 | EP2070545   | Oral compositions for the prevention and treatment of inflammatory disorders of the colon.                                                                                                                       | Bios Line S.p.a. Viale Finladia 4 35020 Ponte S. Nicolo (PD) / Italy[2009/25]                                                     | 10-Dec-08   |
|   21 | EP2101800   | Extracts from the skin of fruits of plants from genus vitis, compositions containing the same and a process for its manufacture.                                                                                 | Aché Laboratórios Farmacêuticos S.A. Rodovia Presidente Dutra Km 222,2 Porto da Igreja 07034-904 Guarulhos- SP /Brazil [2009/39]  | 14-Dec-07   |
|   22 | EP1949889   | Fibroblast activator, method for activation of fibroblast, collagen synthesis promoter, method for promotion of collagen synthesis, skin aging-preventing agent, and method for prevention of aging of the skin. | Mercian corporation 5-8, Kyobashi 1-chome Chuo- ku, Tokyo 104-8305 / Japan[2008/31]                                               | 17-Oct-06   |
|   23 | EP1709995   | Asthma/allergy therapy using nigella sativa.                                                                                                                                                                     | Al-Jassim, Rawaa 2578 River Wood Drive Napperville, Illinois 60565 / United States, Great Britain, Germany, Netherlands and Qatar | 2-Mar-00    |
|   24 | EP1958641   | Treatment and prevention of inflammation.                                                                                                                                                                        | Bionature E.A. Limited 1 Poseidon 2406 Egomi, Nicosia/ Cyprus [2008/34]                                                           | 16-Feb-07   |
|   25 | EP1729593   | Cysteine Protease from Ginger                                                                                                                                                                                    | Natbio Pty Ltd. 41/8 Goodwin Street Kangaroo Point, QLD 4169 / Australia [2006/50]                                                | 23-Feb-05   |
|   26 | EP1971354   | Composition comprising liquiritigenin for preventing and treating liver disease.                                                                                                                                 | Seoul National University Industry Foundation San 4- 2, Bongcheon-dong, Gwanak-gu Seoul 151-818 / South Korea [2008/39]           | 5-Jan-07    |

|   27 | EP2089505   | Reduced-hangover alcoholic beverage.                                                                                   | Morning-After Herbal Infusion Corporation 180 Boul. rene-Levesque East Suite 208 Monreal, QC H2X 1N6 / Canada [2009/34]    | 8-Nov-07   |
|------|-------------|------------------------------------------------------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------------------------|------------|
|   28 | EP1942917   | Compositions and methods for Use of juice organic, juice based skin care products.                                     | Juice Beauty 711 Grand Avenue, Suite 290 San Rafael, CA 94901 / US                                                         | 30-Oct-06  |
|   29 | EP2175848   | Therapeutic uses of Cannabigerol.                                                                                      | GW Pharma Limited Porton Down Science Park Salisbury Wiltshire SP4 0JR / Great Britain [2010/16]                           | 25-Jun-08  |
|   30 | EP2218455   | Dolichos biflorus extract for use in therapeutic skin treatment.                                                       | Cognis IP Management GmbH Henkelstrasse 67 40589 Dusseldorf / Germany[2010/33]                                             | 7-Feb-09   |
|   31 | EP2014295   | Topical compositions for the prevention and treatment of inflammatory and/or infective conditions of the genital area. | Velleja Research SRL Via Natta, 28 29010 Pontenure (PC) / Italy [2009/03]                                                  | 28-May-08  |
|   32 | EP2008661   | Formulation based on marigold aloe and centellae.                                                                      | Spannagel, Lucia Antonia Guemes 235, barrio Los Eucaliptos Villa Carlos Paz Provincia de Cordoba / Argentina[2009/01]      | 5-May-08   |
|   33 | EP1759706   | Use of mash of Gentiana root and corresponding agents.                                                                 | Priebe, Ingrid Thierschstrasse 10 83471 Schonau / Germany[2007/10]                                                         | 4-Sep-06   |
|   34 | EP2167072   | Use of Oleocanthal for Treatment of Cutaneous Inflammation.                                                            | B.C. DEVELOPMENT S.A. route de France 17 / CP 18 2926 Boncourt / Switzerland,Sprim 2 Square Petrarque 75016 Paris / France | 4-Jul-08   |
|   35 | EP2029150   | Extract of Herbal and the composition containing the same.                                                             | DONG-A PHARM. CO., LTD. 252, Yongdu-dong Dong- daemun-ku Seoul 130-823 / Republic Of Korea                                 | 27-Feb-07  |
|   36 | EP2263481   | Green tea extracts of improved bioavailability.                                                                        | Nestec S.A. Avenue Nestle 55 1800 Vevey / Switzerland                                                                      | 29-May-09  |
|   37 | EP1553851   | Cosmetic composition for preventing and/or correcting the functional disorders of the pilo- sebaceous unit of mammals. | L'Oreal 14, rue Royale 75008 Paris / France Nestec S.A. Avenue Nestle 55 1800 Vevey / Switzerland                          | 16-Dec-03  |
|   38 | EP1755402   | Compositions for inhalation therapy and methods of use.                                                                | Tower Laboratories, Ltd. 8 Industrial Park Road Centerbrook, CT 06409 / United States                                      | 6-May-05   |

|   39 | EP1140123   | Use of tropical root crops in effective intervention strategies for treating difficult and complex cases and chronic diseases.                                                   | Slimak, Karen M. P.O. Box 2444 Springfield, VA 22152 / United States                                                 | 13-Nov-00   |
|------|-------------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------------------|-------------|
|   40 | EP2146739   | Methods of immune or hematological enhancement, inhibiting tumour formation or growth, and treating or preventing cancer, cancer symptoms, or the symptoms of cancer treatments. | Fonterra Co-Operative Group Limited 9 Princes Street Auckland / New Zealand                                          | 14-May-08   |
|   41 | EP1925311   | Use of a plant extract or plant juice                                                                                                                                            | BIOPROGRESS TECHNOLOGY LIMITED Units 15-17 Cambridge Science Park Milton Road Cambridge, CB4 0FQ / Great Britain     | 15-Nov-06   |
|   42 | EP2152284   | A SYNERGISTIC AYURVEDIC / FUNCTIONAL FOOD BIOACTIVE COMPOSITION [CINCATA]                                                                                                        | Avesthagen Limited Discoverer' 9th Floor International Tech Park Whitefield Road Bangalore Karnataka 560 066 / India | 29-Jun-07   |
|   43 | EP1609476   | Composition for treating Hepatitis C                                                                                                                                             | Original Image Co., Ltd. 3- 21-2 Motohama-cho Naka- ku Yokohama-shi Kanagawa 231-0004 / Japan                        | 4-Mar-04    |
|   44 | EP1991241   | compositions and methods for the induction and maintenance of quality sleep                                                                                                      | Iomedix Sleep International SRL The Grove 21 Pine Road Belleville 11113 Saint Michael / Barbados                     | 14-Jul-06   |
|   45 | EP1855701   | Metal Chelator                                                                                                                                                                   | Georgiou, George J. Panayia Aimatousa 300 Aradippou 7101, Larncaca / Cyprus                                          | 1-Feb-06    |
|   46 | EP1906982   | Plant extracts and methods and uses therefore                                                                                                                                    | Avesthagen Limited Unit 3, Discoverer, 9th Floor International Tech Park Whitefield Road Bangalore 560 066 / India   | 23-Feb-05   |
|   47 | EP2223616   | Food supplement preparation with an active ingredient mixture                                                                                                                    | PM-International AG 17, rue des Gaulois 1618 Luxembourg                                                              | 13-Feb-09   |
|   48 | EP1998758   | Spray composition for topical use for treating and/or preventing herpes simplex labial infections                                                                                | Istituto Farmacoterapico Italiano S.P.A. Via Paolo Frisi 21/23 00197 Rome / Italy                                    | 21-Mar-03   |
|   49 | EP1718143   | Agents for Sequestering Serum Aging factors and uses therefore                                                                                                                   | Nu Skin International, Inc. 75 West Center Street Provo, UT 84601 / United States                                    | 4-Feb-05    |

|   50 | EP2033650   | Inhibitor of Expression Of Nuclear Transcription Factor Ap-1,and Pharmaceutical product and product using the inhibitor           | ARKRAY, Inc. 57 Nishiaketa-cho Higashikujo Minami-ku Kyoto-shi, Kyoto 601-8045 / Japan                  | 19-Jun-07   |
|------|-------------|-----------------------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------------------------------------------|-------------|
|   51 | EP2251032   | Lactoferrin and brain health and protection in adults                                                                             | Nestec S.A., Avenue Nestle 55, 1800 Vevey/ Switzerland                                                  | 12-May-09   |
|   52 | EP2251029   | Lactoferrin and gut neuronal health in adults and/or elderly                                                                      | Nestec S.A. Avenue Nestle 55 1800 Vevey/ Switzerland                                                    | 12-May-09   |
|   53 | EP1812028   | Herbal composition phy906 and its use in Chemotherapy.                                                                            | Yale University Two Whitney Avenue New Haven, CT 06511 / United States                                  | 9-Nov-05    |
|   54 | EP2371374   | Soluble fiber from Musa spp. for treating gastroenteritis or diarrhea                                                             | PROVEXIS (IBD) LIMITED Thames Court 1 Victoria Street Windsor Berkshire SL4 1YB / United Kingdom        | 10-Feb-04   |
|   55 | EP1498132   | Compositions for preventing or treating Pollenosis, Allergic Nephritis, Atopic Dermatitits, Asthma or Urticaria                   | Original Image Co., Ltd., 21-2 Motohama-cho 3- chome Naka-ku Yokohama- shi, Kanagawa 231-0004/ JAPAN    | 21-Apr-03   |
|   56 | EP1945237   | Use of Extracts of Myrtle and other Mediterranean plant species, as Antimycotic agent towards Yeast and Yeast-like Microorganisms | Romani, Annalisa, Via Delle Lame 4, 51031 Agliana / ITALY                                               | 17-Oct-06   |
|   57 | EP1863498   | Composition Comprising Isoorientin for Suppressing Histamine                                                                      | Unigen, Inc. 200-1, Songjeong-ri Byeongcheon- myeon, Cheonan-si Chungcheongnamdo 330- 863 / South Korea | 17-Mar-06   |
|   58 | EP2094091   | Antimicrobial Composition                                                                                                         | Nature Therapeutics Limited, 4 Mill Fields Bassingham Lincoln, Lincolnshire LN5 9NP / United Kingdom    | 6-Dec-07    |
|   59 | EP2086560   | Methods of treating Epiphora                                                                                                      | Riolan Technologies, Inc., 8575 Prestwick Drive, La Jolla, CA 92037 / United States                     | 1-Nov-07    |
|   60 | EP2251024   | Plant-Origin drug for preventing or improving Hyperuricemia                                                                       | Kaneka Corporation, 2-4, Nakanoshima 3-chome Kita-ku, Osaka-shi, Osaka 530-8288 / Japan                 | 21-Jan-09   |
|   61 | EP2163252   | Composition containing Licorice- derived Polyphenol                                                                               | Kaneka Corporation, 2-4, Nakanoshima 3-chome Kita-ku, Osaka-shi, Osaka 530-8288 / Japan                 | 16-May-08   |

|   62 | EP2144591   | Personal care compositions comprising an Antimicrobial Blend of essential oils or constituents thereof                                                                                                       | The Procter & Gamble Company, One Procter & Gamble Plaza, Cincinnati, OH 45202 / United States    | 15-Apr-08   |
|------|-------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------------------------------------|-------------|
|   63 | EP1841320   | Methods and pharmaceutical compositions useful for treating psoriasis                                                                                                                                        | S.U.L.V.E. Ltd., P.O. Box 899, Business Center, 25147 Kfar-vradim / Israel                        | 12-Jan-06   |
|   64 | EP2227247   | Anticancer composition comprising plant stem cell line derived from Taxus Cambium or Procambium                                                                                                              | Unhwa Corporation, 865-5 Hoseongdong 1-gaDeokjin- guJeonju-si, Jeollabuk-do 561-211 / South Korea | 10-Oct-08   |
|   65 | EP2139504   | Standardized Bioactive Herbal Extracts                                                                                                                                                                       | Ranbaxy Laboratories Limited., Plot No. 90, Sector-32 Gurgaon, Haryana 122001, Delhi / INDIA      | 24-Mar-08   |
|   66 | EP2377543   | Ophthalmic, pharmaceutical and other healthcare preparations with naturally ocurring plant compounds, extracts and derivatives                                                                               | Natural Disinfectant Technologies., Landhuis Joonchi, P.O. Box 837, Curacao / NETH. ANTILLES      | 4-Apr-03    |
|   67 | EP2157978   | MC-1 R, MC-2 R, and MU Opioid Receptors Modulation                                                                                                                                                           | BASF Beauty Care Solutions France SAS, France                                                     | 6-Jun-08    |
|   68 | EP2144621   | Guava Extract                                                                                                                                                                                                | OMNICA GMBH, Plan 5, 20095 Hamburg / Germany                                                      | 22-Apr-08   |
|   69 | EP2046357   | Antioxidant compositions comprising extracts of Myrtle and Rosemary                                                                                                                                          | Nuraging Biotech S.r.l., Localita Piscinamanna, edif.5, 09010 Pula (CA) / Italy                   | 24-Jul-07   |
|   70 | EP2323501   | Reduced sesame seed derived pigments                                                                                                                                                                         | OMNICA GMBH, Plan 5, 20095 Hamburg / Germany                                                      | 28-Jul-09   |
|   71 | EP2349305   | Phytochemical Compositions and Methods for Activating Amp-Kinase                                                                                                                                             | Metaproteomics LLC / United States                                                                | 4-Nov-09    |
|   72 | EP2060621   | Wheat-germ oil concentrate, a method for the production thereof, a method for producing wheat- germ oil and a medicinal and prophylactic composition based thereon and used for treating sexual dysfunctions | Otkrytoe Aktsionernoe Obschestvo Zavod Ekologicheskoy Tekhniki, Moscow 115114 / Russia            | 27-Nov-06   |
|   73 | EP1825861   | Anti-inflammatory extract and agent and method for the production thereof                                                                                                                                    | Otkrytoe Aktsionernoe Obschestvo Zavod Ekologicheskoy Tekhniki I Ekopitaniya 'Diod' / Russia      | 15-Nov-05   |
|   74 | EP2094094   | Composition comprising a milled cereal product                                                                                                                                                               | F. Coy, Johannes F. , Mestemacher GmbH / Germany                                                  | 7-Dec-07    |
|   75 | EP1998727   | Herbal composition for treatment of infections caused by Dermatophytes /                                                                                                                                     | Piramal Enterprises Limited India                                                                 | 27-Mar-07   |

|   76 | EP2124636   | Novel use of (-)-Epigallocatechin Gallate                                                                         | DSM IP Assets B.V., Het Overloon 1, 6411 TE Heerlen / Netherlands                                                     | 17-Jan-08   |
|------|-------------|-------------------------------------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------------------------------------|-------------|
|   77 | EP2204176   | Nutritional Composition                                                                                           | Societe des Produits Nestle S.A., P.O.Box 353, 1800 Vevey / Switzerland                                               | 17-Jul-01   |
|   78 | EP2089044   | Anti-obesity product and it's method of preparation                                                               | Chongquing institute of Ecological Materia Medica Co Limited / China and Phynova Limited/ Great Britain               | 9-Jul-07    |
|   79 | EP1993522   | Resveratrol and/or Grape leaf extract as i.a. Endurance Improver, Anti-aging agent, Muscle strength improver      | Kao Corporation 14-10, Nihonbashi-Kayabacho, 1- chome Chuo-ku Tokyo 103- 8210 / Japan                                 | 25-Oct-06   |
|   80 | EP2269598   | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2  | Metaproteomics, LLC / US                                                                                              | 17-Jul-02   |
|   81 | EP2293689   | Food product                                                                                                      | Mars, Incorporated / US                                                                                               | 28-May-09   |
|   82 | EP1901701   | Personal care and medicinal products incorporating bound Organosulfur groups                                      | Ott, David M., 777 Panoramic Way, Berkeley, CA 94704 / US                                                             | 24-May-06   |
|   83 | EP1881839   | Compositions of Bakuchiol and methods of making the same                                                          | Unigen, Inc. / US                                                                                                     | 9-May-06    |
|   84 | EP2419508   | Method for the induction of a reward response by modulation of dopaminergic systems in the central nervous system | Somalabs, Inc., 40 Allen Road, South Burlington, VT 05403 / US                                                        | 16-Apr-10   |
|   85 | EP1558271   | Compositions that treat or inhibit pathological conditions associated with inflammatory response                  | Metaproteomics, LLC / US                                                                                              | 20-Oct-03   |
|   86 | EP2266586   | Compositions and method for alleviating inflammation and oxidative stress in a mammal                             | Lifeline Nutraceuticals Corporation 6400 South Fiddler's Green Circle, Suite 1970 Englewood, CO 80111 / United States | 23-Mar-05   |
|   87 | EP2243383   | A method and composition for nutritionally improving glucose control and insulin action                           | Nestec S.A. / Switzerland                                                                                             | 4-Apr-06    |
|   88 | EP2361602   | A hair building solid agent                                                                                       | M/S Pangaea Laboratories Limited / Great Britain                                                                      | 11-Feb-11   |
|   89 | EP2689806   | Oral compositions containing extracts of myristica fragrans and related methods                                   | Colgate-Palmolive Company / United States of America                                                                  | 1-Dec-10    |
|   90 | EP2328598   | Novel compositions containing isolated Tetrameric type a Proanthocyanadin and methods of use and manufacture      | Phenolics, LLC / US                                                                                                   | 4-Aug-09    |

|   91 | EP1572219   | Efficient method for producing compositions enriched in total phenols                                                                                                                                                                                             | Phenolics, LLC, P.O. Box 2439, 846 San Carlos Avenue, El Granada, CA 94108-2439 / US       | 21-Nov-03   |
|------|-------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------|-------------|
|   92 | EP1941899   | Agent for promoting Glucagon-like Peptide 1 Secretion, food or drink for promoting Glucagon-like Peptide 1 Secretion, agent for inhibiting postprandial increase in blood sugar level and food or drink for inhibiting postprandial increase in blood sugar level | Morinaga Milk Industry Co., Ltd., 33-1, Shiba 5-chome, Minato-ku, Tokyo 108-8384 / Japan   | 29-Sep-06   |
|   93 | EP2192910   | Oral compositions containing botanical extracts                                                                                                                                                                                                                   | Colgate-Palmolive Company, 300 Park Avenue, New York, NY 10022/ United States of America   | 29-Sep-08   |
|   94 | EP2415469   | Anti-resorptive and bone building dietary supplements and methods of use                                                                                                                                                                                          | Krempin, David W. , 30150 Corte Cantera, Temecula, CA 92591 / US                           | 24-Oct-07   |
|   95 | EP2367526   | Compositions and methods for alleviating hyposalivation and for providing oral comfort                                                                                                                                                                            | VDF Futureceuticals, Inc., 819 Dixie Highway, Momence, IL 60954 / United States of America | 13-Nov-09   |
|   96 | EP1883416   | Compositions and methods for the prevention and treatment of conditions associated with inflammation                                                                                                                                                              | Wellgen, Inc, 63 Dudley Road, New Brunswick NJ 08901-8520 / US                             | 24-May-06   |
|   97 | EP2691072   | Triglyceride Compositions of Plant Origin for Cosmetic Applications Obtained from Olive Oil Deodorization Distillate                                                                                                                                              | M/S LEHVOSS ITALIA s.r.l. / Italy                                                          | 29-Mar-12   |
|   98 | EP1849473   | Chinese traditional medicine composition for treatment of avian influenza/Bird Flu, method for preparation, and application thereof.                                                                                                                              | Livzon Pharmaceutical Group Inc., CN, China                                                | 19-Jan-07   |
|   99 | EP1722805   | Bioactive compositions from Theacea plants and processes for their production and use                                                                                                                                                                             | Integrated Botanical Technologies, 23 Snowden Avenue, Ossining, New York 10562-3218 / US   | 12-Jan-05   |
|  100 | EP1880719   | Composition for prophylaxis or treatment of urinary system infection and method thereof.                                                                                                                                                                          | CHIH-HSIUNG LIN, Taiwan, Province of China                                                 | 6-Jun-07    |
|  101 | EP2153831   | Anti-Fatigue Agent and Oral composition each comprising Andrographolide as active ingredient                                                                                                                                                                      | Suntory Holdings Ltd. / Japan                                                              | 30-May-08   |

|   102 | EP2062883   | Insulin sensitivity improving agent.                                                                                                                                                                         | Kao Corporation 14-10, Nihonbashi-Kayabacho, 1- chome Chuo-ku Tokyo 103- 8210 / Japan                                                                                                                                             | 5-Sep-07   |
|-------|-------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------|
|   103 | EP1795200   | Medicine and food/beverage for ameliorating hyperglycemia.                                                                                                                                                   | MORINAGA MILK INDUSTRY CO., LTD. 33-1, Shiba 5-chome Minato-ku, Tokyo-to 108-0014 / Japan                                                                                                                                         | 30-Mar-05  |
|   104 | EP2223930   | Eriocitrin-containing material, method for production of the Eriocitrin-containing material, and food, beverage, pharmaceutical preparation and cosmetic each comprising the Eriocitrin- containing material | POKKA CORPORATION, 4- 2-29, Sakae Naka-ku Nagoya-shi, Aichi 460-8415 / Japan                                                                                                                                                      | 26-Dec-08  |
|   105 | EP2112929   | Catechin as Insulin sensitivity improving agent                                                                                                                                                              | Kao Corporation 14-10, Nihonbashi-Kayabacho, 1- chome Chuo-ku Tokyo 103- 8210 / Japan                                                                                                                                             | 28-Nov-07  |
|   106 | EP2182963   | Herbal Composition on the basis of extracts of Foeniculum Vulgare, Murraya Koenigii and Triphala                                                                                                             | "Delhi Institute Of Pharmaceutical Sciences And Research (DIPSAR) Pushp Vihar Sector III New Dehli 110 017 / India" and "Promed Exports Private Limited 210 Ashirwad Commercial Complex D-1 Green Park New Delhi 110 016 / India" | 17-Jun-08  |
|   107 | EP2229403   | Recovery of hydrophobic peptides from oils                                                                                                                                                                   | University of Saskatchewa Box 5000, RPO University Suite 501-121 Research Drive Saskatoon, Saskatchewan S7N 1K5 / Canada                                                                                                          | 22-Dec-08  |
|   108 | EP2155222   | Extract of Trigonella Foenum- Graecum                                                                                                                                                                        | BIOTEK HOLDING APS V. Vimmelskaftet 43 1161 Copenhagen K / Denmark                                                                                                                                                                | 14-Apr-08  |
|   109 | EP2269621   | Agents for maturing, normalizing or stabilizing blood vessels and wrinkle-preventing and improving agents                                                                                                    | Shiseido Company Ltd., 5-5 Ginza 7-chome Chuo-ku, Tokyo 104-8010 / Japan                                                                                                                                                          | 31-Mar-09  |
|   110 | EP2319537   | Stabilizer for Lymph Vessel                                                                                                                                                                                  | Shiseido Company Ltd., 5-5 Ginza 7-chome Chuo-ku, Tokyo 104-8010 / Japan                                                                                                                                                          | 17-Jun-09  |
|   111 | EP1859834   | Anti-Inflammatory agent                                                                                                                                                                                      | Maruzen Pharmaceuticals Co., Ltd., 14703-10, Mukaihigashi-cho Onomichi-shi, Hiroshima 7220062 / Japan                                                                                                                             | 15-Mar-05  |
|   112 | EP2303298   | Compositions comprising extracts from Boswellia Serrata                                                                                                                                                      | Ganga Raju Gokaraju, Andhra Pradesh / India                                                                                                                                                                                       | 2-Jun-09   |

|   113 | EP2379095   | Compositions Comprising Lipophilic extracts of Zingiber Officinale and Echinacea Angustifolia for the prevention and treatment of Gastro-Oesophageal Reflux                                     | Indena S.p.A., Via Ortles, 12, 20139 Milano / Italy                                                        | 15-Jan-10   |
|-------|-------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------------------------------------------------------------------------------------------------------|-------------|
|   114 | EP2275113   | Skin circulation-improving agent and skin temperature-elevating agent                                                                                                                           | Shiseido Company, Ltd., 5- 5 Ginza 7-chome Chuo-ku, Tokyo 104-8010/ JAPAN                                  | 26-Mar-09   |
|   115 | EP2134316   | Novel cosmetic and/or pharmaceutical compositions and applications thereof                                                                                                                      | Legacy Healthcare Holding Ltd., 85, St. John Street, Valleta VLT 1165 / Malta                              | 8-Feb-08    |
|   116 | EP2262503   | Formulations with Sanguinarine, Chelerythrine or Chelidonine for the treatment of Warts, Verrucas and Psoriatic Plaques                                                                         | INDENA S.p.A., Viale Ortles, 12, 20139 Milano / ITALY                                                      | 9-Mar-09    |
|   117 | EP1781235   | Anti-hypersensitive Inflammation and Anti-allergy activities of Zingiber Zerumbet                                                                                                               | Wholesome Life Science Co., Ltd. 5F, 170, Sec 3 Ming-Chuan E. Rd Taipei 105 / Taiwan                       | 18-Jul-05   |
|   118 | EP2379092   | Compositions comprising a Lipophilic extract of Zingiber Officinale and an extract of Cynara Scolymus                                                                                           | INDENA S.p.A., Viale Ortles, 12, 20139 Milano / ITALY                                                      | 15-Jan-10   |
|   119 | EP2493490   | harmaceutical or Veterinary Medical preparation obtained from Coconut                                                                                                                           | Mehlhorn, Heinz / GERMANY, King Saud University / Saudi Arabia                                             | 8-Oct-09    |
|   120 | EP2152281   | Composition for treatment of ischemic heart disease, facilitation of blood circulation and angiogenesis, improving skin beauty, improving male sexual function containing ginseng berry extract | Amorepacific Corporation, 181, 2-ga Hangang-ro Yongsan-gu, Seoul 140- 777 / Republic of Korea              | 28-May-08   |
|   121 | EP1296698   | Therapeutic Agents - II                                                                                                                                                                         | Peplin Research Pty Ltd, Ground Floor, South Tower, 527 Gregory Terrace, Bowen Hills, QLD 4006 / Australia | 7-Jun-01    |
|   122 | EP2416793   | A plant extract comprising statins and preparation techniques and uses thereof                                                                                                                  | Nanyang Polytechnic / Singapore                                                                            | 8-Apr-10    |
|   123 | EP2052731   | Composition for preventing and/or treating Itching containing component originating in the Bark of Tree Belonging to the Genusacacia                                                            | Mimozax Co., Ltd. , 4291- 1, Miyauchi Hatsukaichi- shi, Hiroshima 738-0034 / Japan                         | 10-Aug-06   |
|   124 | EP2506724   | Vigna Unguiculata seed extract and compositions containing the same                                                                                                                             | Laboratoires Expanscience / France                                                                         | 30-Nov-10   |
|   125 | EP2226071   | Composition for oral administration                                                                                                                                                             | Unitika, Ltd. / Japan                                                                                      | 28-Aug-08   |

|   126 | EP2046324   | Treatment and prevention Mucositis by Anthocyanidin derivatives                               | M/S Indena S.p.A. / Italy                                                                       | 27-Jul-07   |
|-------|-------------|-----------------------------------------------------------------------------------------------|-------------------------------------------------------------------------------------------------|-------------|
|   127 | EP1750651   | Composition for improving skin, hair and coat health containing flavanones                    | Nestec S.A., Avenue Nestle 55, 1800 Vevey / Switzerland                                         | 17-Dec-04   |
|   128 | EP1827362   | Compositions and methods of their use for improving the condition and appearance of skin      | Avon Products, Inc. / US                                                                        | 28-Nov-05   |
|   129 | EP2157966   | MC-1R, MC-2R, AND/OR [mu] OPIOID RECEPTORS STIMULATION                                        | BASF Beauty Care Solutions France SAS / France                                                  | 6-Jun-08    |
|   130 | 20100203117 | Anti-adipogenic compositions containing piper betle and dolichos biflorus.                    | Kramer & Amado, P.C. 1725 Duke Street, Suite 240,Alexandria, VA, 22314, United States           | 24-Mar-10   |
|   131 | 20100203078 | Anti-obese compositions containing holoptelea integrifolia extracts.                          | LAILA NUTRACEUTICALS, Vijayawada, India                                                         | 20-Aug-07   |
|   132 | 20110097424 | Herbal formulations for the management of chronic ulcers and wounds.                          | Apptec Inc,C/o Bregen TechnicaL ConsultantS L.L.C., 154 old clinton road flemington nj 08822    | 26-Oct-10   |
|   133 | 20110052737 | Topical skin formulations comprising Botanical Extracts.                                      | Mary Kay Inc.Dallas Texas, United States                                                        | 12-Aug-10   |
|   134 | 20100178367 | Herbal formulation for Wound Healing                                                          | Manish Saxena , New Delhi, India                                                                | 25-Mar-10   |
|   135 | 20100129296 | Extract of Trigonella Foenum- Graecum.                                                        | SUGHRUE MION, PLLC 2100 PENNSYLVANIA AVENUE, N.W.,SUITE 800, WASHINGTON DC 20037, United States | 17-Nov-09   |
|   136 | 20110177184 | Bloat therapeutic agent for a Ruminant                                                        | Chie Suzuki, Kyo Nagashima, Masami Mochizuki, Japan                                             | 28-Sep-09   |
|   137 | 20100203178 | Synergistic Herbal Composition                                                                | Suresh Kumar Gupta, New Delhi, India                                                            | 22-Apr-10   |
|   138 | 20100291249 | Pomegranate-derived Products for the Treatment of Skin Sores and Lesions                      | MDIP LLC, Post Office Box 2630 Montgomery Village, MD, 20886-2630, US                           | 27-Jul-10   |
|   139 | 20110118346 | Novel use of Lignan-type compounds or extract of Nutmeg or Aril of Nutmeg comprising the same | Hwang; Jae Kwan; Cho; Yu-Mi; Kim; Gyu Hoi; South Korea                                          | 17-Oct-08   |
|   140 | 20120128808 | Agents from Ficus Hispida for the Amelioration of Metabolic syndrome and related diseases     | Laila Nutraceuticals, India                                                                     | 2-Feb-12    |
|   141 | 20130005830 | Sandalwood oil and its uses                                                                   | Santalis Pharmaceuticals Inc., US                                                               | 31-Aug-12   |

|   142 | 20120115891                                                                      | Method for the induction of a reward response by modulation of dopaminergic systems in the central nervous system                   | Somalabs Inc., US                                                                                    | 1-Mar-12   |
|-------|----------------------------------------------------------------------------------|-------------------------------------------------------------------------------------------------------------------------------------|------------------------------------------------------------------------------------------------------|------------|
|   143 | 20120329739 treating Poliosis or comprising a Pueraria genus extract or Puerarin | Composition for preventing or Vitiligo plant                                                                                        | Kim; Hyoung-Jun, Korea                                                                               | 31-Aug-12  |
|   144 | 20100239696                                                                      | Flaxseed lignan complex, methods of using and compositions thereof                                                                  | Pearl Cohen Zedek Latzer, LLP, 1500 Broadway, 12th Floor, New York 10036, United States              | 1-Jun-10   |
|   145 | 20090269398                                                                      | Compositions for the encapsulation of natural product extracts in oil medium in hard gelatin capsules and a method of encapsulation | Vilambi NRK Reddy, US                                                                                | 26-Apr-08  |
|   146 | 20100173022                                                                      | Composition for the treatment of Diabetes Mellitus and Metabolic Syndrome                                                           | Morrison & Foerster LLP, 12531 High Bluff Drive, Suite 100, San Diego, CA, 92130-2040, United States | 22-Mar-10  |
|   147 | 20100061944                                                                      | Oral hygiene composition comprising myrtle                                                                                          | Mars Incorporated, US                                                                                | 14-Aug-09  |
|   148 | 20120231032                                                                      | Agent for expelling parasites in humans, animals or birds                                                                           | Maria Wilhemina Meijs, US                                                                            | 3-May-12   |
|   149 | 20130017279                                                                      | Formulations for treatment of skin disorders                                                                                        | N. B. Baktha Reddy, Chennai, India                                                                   | 13-Sep-12  |
|   150 | 20130095171                                                                      | Herbal composition and method for treatment of airway inflammation using the same                                                   | Taichung Veterans General Hospital, Taiwan                                                           | 11-Oct-12  |
|   151 | 20080199550                                                                      | Novel Anticancer Agent, Methods for Obtaining the Same and Pharmaceutical Compositions Thereof                                      | MMI Corporation, US                                                                                  | 29-Feb-08  |
|   152 | 20110305779                                                                      | Phytochemical combinations that regulate pathological immunity                                                                      | COWAN; Fred M., US                                                                                   | 9-Jun-11   |
|   153 | 20140106002                                                                      | Homeopathic composition and method for the treatment of Skin Irritations and other Skin diseases                                    | M/S Jensen; Ned L, US                                                                                | 15-Mar-13  |
|   154 | 20130337057                                                                      | Novel herbal composition for the treatment of kidney stone and other urinary tract disorders                                        | M/S Patankar; Suresh Balkrishna, India                                                               | 3-Sep-03   |
|   155 | CA 2387703                                                                       | Method for calming human beings using personal care compositions.                                                                   | Johnson & Johnson Consumer Companies Inc, United States of America                                   | 29-Feb-00  |
|   156 | CA 2579562                                                                       | Method for improving sleep behaviors.                                                                                               | Johnson & Johnson Consumer Companies Inc, United States of America                                   | 26-Feb-07  |
|   157 | CA 2448513                                                                       | Isoflavone Concentrates, as well as methods for their production.                                                                   | Aquanova German Solubilisate Technologies (AGT) GMBH, Germany                                        | 29-Jun-02  |

|   158 | CA 2366318   | Novel pharmaceutical, dietary and cosmetic compositions comprising zinger officinale roscoe, eicosapentaenoic acid and/or docosahexaenoic acid.   | IDA ROYALTY APS, Denmark                        | 2-Mar-00   |
|-------|--------------|---------------------------------------------------------------------------------------------------------------------------------------------------|-------------------------------------------------|------------|
|   159 | CA 2572031   | Fat combustion accelerator.                                                                                                                       | SUNTORY LIMITED, Japan                          | 29-Jun-05  |
|   160 | CA 2616602   | Method of treatment or management of Stress                                                                                                       | NATREON, INC. (United States of America)        | 27-Jul-06  |
|   161 | CA 2697020   | Method of producing Plant extract formulations                                                                                                    | QUINN PHARMACEUTICALS, Australia                | 20-Aug-08  |
|   162 | CA 2409051   | Antimigraine Combination Comprising Sapindus and Emblica Extracts                                                                                 | LUPIN LIMITED, India                            | 25-May-00  |
|   163 | CA 2625433   | Carotenoid Oxidation products as Chemopreventive and Chemotherapeutic Agents                                                                      | LYCORED LTD., Israel                            | 5-Oct-06   |
|   164 | CA 2642184   | Composition containing ginseng and cinnamon                                                                                                       | Goliath Oil and Gas Corporation, Canada         | 28-Oct-08  |
|   165 | CA 2470603   | Methods for the treatment of peripheral Neural and Vascular Ailments                                                                              | THE QUIGLEY CORPORATION, USA                    | 6-Nov-02   |
|   166 | CA 2467664   | Methods of making and using Theaflavin, Theaflavin-3-Gallate, Theaflavin-3'-Gallate and Theaflavin 3,3'-Digallate and Mixtures Thereof            | Nashai Biotech, LLC, United States of America   | 27-Nov-07  |
|   167 | CA 2530345   | Composition and method for Mitigating a negative effect of Alcohol consumption.                                                                   | EFFECTLIVE INC. (Canada)                        | 15-Dec-05  |
|   168 | CA 2473143   | Compositions containing Oat Straw and Willowherb Extract.                                                                                         | JOHNSON & JOHNSON GMBH ((Germany))              | 10-Feb-03  |
|   169 | CA 2485389   | Formulations useful in the treatment of male and female impotence.                                                                                | INDENA S.P.A.(Italy)                            | 2-May-03   |
|   170 | CA 2485264   | Formulations useful in the treatment of male and female impotence.                                                                                | INDENA S.P.A.(Italy)                            | 30-Apr-03  |
|   171 | CA 2601777   | Compositions and methods for enhancing cognitive function.                                                                                        | SIGNUM BIOSCIENCES, INC., USA                   | 3-Feb-06   |
|   172 | CA 2485530   | Throat Spray.                                                                                                                                     | CNS, INC. USA                                   | 14-Feb-03  |
|   173 | CA 2445373   | Use of Phyllanthus constituents for treating or preventing infections caused by Hepatitis B viruses.                                              | PHYTRIX AG (Germany)                            | 26-Apr-02  |
|   174 | CA 2555728   | Agents for sequestering serum aging factors and uses therefore.                                                                                   | Nu Skin International, Inc. (USA)               | 4-Feb-05   |
|   175 | CA 2454171   | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of Cyclooxygenase-2                                  | Metaproteomics, LLC. (United States of America) | 17-Jul-02  |

|   176 | CA 2588119   | Composition and method for facilitating the healing of non- healing and slow-healing wounds and ulcerations                  | Berkson, Lindsey (United States of America)                      | 17-Nov-05   |
|-------|--------------|------------------------------------------------------------------------------------------------------------------------------|------------------------------------------------------------------|-------------|
|   177 | CA 2334621   | Composition and method for treatment of Inflammation and Pain in Mammals                                                     | Metagenics, INC. (United States of America)                      | 10-Apr-00   |
|   178 | CA 2632684   | Protein Kinase modulation by hops and acacia products                                                                        | Metaproteomics, LLC (United States of America)                   | 11-Dec-06   |
|   179 | CA 2570989   | Product of vegetal origin comprising Proanthocyanidines and its preparation process                                          | Investigacion Y Nutricion, S.L. (Spain)                          | 21-Jun-05   |
|   180 | CA 2511431   | Pharmaceutical compositions comprising Flavonoids and Menthol                                                                | Immupharm A/S (Denmark)                                          | 19-Sep-03   |
|   181 | CA 2679847   | Methods and compositions for promoting bone and joint health                                                                 | Metaproteomics, LLC. (United States of America)                  | 14-Mar-08   |
|   182 | CA 2649514   | Licorice Polyphenol Preparation                                                                                              | Kaneka Corporation (Japan)                                       | 12-Apr-07   |
|   183 | CA 2618613   | Protein Kinase modulation by Hops and Acacia products                                                                        | Metaproteomics, LLC (United States of America)                   | 9-Aug-06    |
|   184 | CA 2584124   | Flavonoid composition for treating oral diseases                                                                             | Unigen Pharmaceuticals, INC. (United States of America)          | 19-Oct-05   |
|   185 | CA 2641950   | All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization | Mannatech, INC. (United States of America)                       | 26-Oct-06   |
|   186 | CA 2684853   | Dietary supplement for promoting wellness and weight loss and methods of administering the same                              | Reliv International, Inc. (United States of America)             | 9-Nov-09    |
|   187 | CA 2606392   | Hair Tonic                                                                                                                   | INDENA S.P.A. (Italy)                                            | 5-Apr-06    |
|   188 | CA 2412435   | Phytonutrient formula for the relief of Chronic pain resulting from Inflammation                                             | WYETH (United States of America)                                 | 13-Jun-01   |
|   189 | CA 2731454   | A herbal and vitamin C composition used for treating Inflammation and the mainenance of good health                          | LEBLANC, RUSSELL (Canada)                                        | 10-Feb-11   |
|   190 | CA 2574518   | Pharmaceutical composition and non dependence coffee comprising edible Carboxylic Acid and/or its Acid Salt and Coffeine     | SHIAO, SHIN-JEN (Taiwan)                                         | 24-Oct-05   |
|   191 | CA 2546464   | Sequential application of oral and topical formulations for treating wrinkles and other damage to skin                       | Wachsberg, Richard (Canada)                                      | 1-May-06    |
|   192 | 2009217410   | Composition for treating skin lesions.                                                                                       | Dynamiclear Pty Ltd, 19 Byrnes Street Mareeba QLD 4880 Australia | 21-Sep-09   |

|   193 | 2008278764      | Fortification of nutritional products with olive extracts containing hydroxytyrosol and hydroxytyrosol fortified nutritional products.                            | PROBELTE PHARMA, S.A., Ctra. Madrid Km.389 Poligono Industrial el Tiro E-30100, Espinardo Murcia Spain                    | 23-Jul-08   |
|-------|-----------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------------------------------------------------------------|-------------|
|   194 | 2009222618      | NGNA compositions and methods of use                                                                                                                              | Life Science Nutrition AS, Industrivegen 42 N-6160 Hovdebygda / Norway                                                    | 7-Oct-09    |
|   195 | 2009240851      | A composition for treating AIDS and associated conditions.                                                                                                        | Willfred-Ramix, Inc., United States of America                                                                            | 26-Nov-09   |
|   196 | GB2448535       | New use for cannabinoid- containing plant extracts.                                                                                                               | GW PHARMA LTD, Porton Down Science Park, SALISBURY, Wiltshire, SP4 0JR / United Kingdom                                   | 19-Apr-07   |
|   197 | 252093          | A Synergistic Ayurvedic/ Functional Food Bioactive Composition                                                                                                    | M/s Avesthagen Limited Discoverer, 9th Floor International Tech Park, Whitefield Road, Bangalore, Karnataka 560066, India | 23-May-07   |
|   198 | 182/MUMNP/200 9 | Cinnamomi and Poria composition and uses thereof                                                                                                                  | Jiangsu Kanion Pharmaceuticals Co Ltd/ China                                                                              | 22-Jan-09   |
|   199 | 881/CHENP/2008  | Process for producing enriched fractions of Tetrahydroxycurcumin and Tetrahydrotetrahydroxycurcumin                                                               | Gogaraju Ganga Raju/ India                                                                                                | 21-Feb-08   |
|   200 | 1576/DEL/2006   | A Novel Herbal Composition Effective against Skin Disorders and to a Process for the Preparation Thereof                                                          | Director, Central Council For Research in Unani Medicine (CCRUM), New Delhi, India                                        | 4-Jul-08    |
|   201 | 1864/DEL/2006   | A novel herbal composition and a process for preparation thereof effective against Diarrhaea and Dysentery                                                        | Central Council for Research in Unani Medicines (CCRUM) / India                                                           | 21-Aug-06   |
|   202 | 1313/DEL/2006   | A preparation for the treatment of running and stuffy nose, productive or non-productive cough with or without fever and to a process for the preparation thereof | Central Council for Research of Ayurveda and Siddha / India                                                               | 31-May-06   |
|   203 | 2426/DEL/2007   | Hard Boiled Herbal Skin Candy                                                                                                                                     | M/S Sharadendu Bali/ India                                                                                                | 20-Nov-07   |
|   204 | 692/DEL/2004    | A Synergistic Pharmaceutical Composition for the Treatment of Cancer                                                                                              | M/S Anshul Kumar Agrawal / India                                                                                          | 8-Apr-04    |
|   205 | 1865/DEL/2006   | A novel herbal composition effective against general weakness and a process thereof                                                                               | Central Council for Research in Unani Medicines (CCRUM) / India                                                           | 21-Aug-06   |
|   206 | 369/DEL/2005    | A composition for the treatment of sex drive and weakness                                                                                                         | Shrivastav, Yashvardhan and Shrivastav, Anand / India                                                                     | 21-Feb-05   |

|   207 | 1642/DEL/2006    | A novel herbal composition effective against headache and a process for the preparation thereof                                      | Central Council for Research in Unani Medicines (CCRUM) / India                               | 17-Jul-06   |
|-------|------------------|--------------------------------------------------------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------------|-------------|
|   208 | 3387/DELNP/200 4 | Formulations useful in the treatment of male and female impotence                                                                    | INDENA S.P.A/ Italy                                                                           | 1-Nov-04    |
|   209 | 1962/MUM/2008    | A herbal formulation for treating sickle cell disease                                                                                | Atul Desai/ India                                                                             | 16-Sep-08   |
|   210 | 1734/DEL/2007    | A novel herbal composition for the treatment of Eczema                                                                               | Central Council for Research in Unani Medicines (CCRUM) / India                               | 14-Sep-07   |
|   211 | 1735/DEL/2007    | A novel herbal preparation for the treatment of Sinusitis                                                                            | Central Council for Research in Unani Medicines (CCRUM) / India                               | 14-Aug-07   |
|   212 | 907/DEL/2005     | A synergistic herbal formulation useful in reducing undesirable after-effects of alcoholic beverages                                 | Anil Sharma / India                                                                           | 8-Apr-05    |
|   213 | 193/CHE/2007     | A herbal preparation effective in the prevention and management of Rheumatoid Arthritis and associated compliants                    | Dr. Swaminathan / India                                                                       | 31-Jan-07   |
|   214 | 172/DEL/2007     | A preparation for treatment of Vitiligo and a method of preparation thereof                                                          | Central Council for Research in Unani Medicines (CCRUM) / India                               | 29-Jan-07   |
|   215 | 212/DEL/2006     | A herbal preparation for the prevention and management of various types of Carcinoma                                                 | Prof. S. S. Trivedi / India                                                                   | 25-Jan-06   |
|   216 | 1783/DEL/2007    | Nutraceutical Biscuits                                                                                                               | Central Council for Research in Unani Medicines (CCRUM) / India                               | 21-Aug-07   |
|   217 | 1732/DEL/2007    | A novel composition of the herbal tea                                                                                                | Central Council for Research in Unani Medicines (CCRUM) / India                               | 14-Sep-07   |
|   218 | 833/DEL/2007     | An Edible Oil Blend Of Mustard and Rice Bran and a Process Thereof                                                                   | M/S Dr.Shakir Ali, Dr.Jafar Salamat Khan, Dr.Malik Zainul Abdin, Mr. Hamid Nawaz Khan / India | 16-Apr-07   |
|   219 | 529/KOL/2007     | Unique Natural Oils and Cream for Recovering the Disease like Spondylosis, Osteo-Arthritis etc and the Process of Producing the Same | M/S Apurba Ganguly / India                                                                    | 2-Apr-07    |
|   220 | 926/CHENP/2010   | Antiobese Compositions containing Holoptelea Integrifolia Extracts                                                                   | M/S Laila Nutraceuticals / India                                                              | 18-Feb-10   |

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