Lok Sabha Question No. 1089 (UNSTARRED), answered on 2017-07-21
Subject: Kidney Failure Cases
Ministry: HEALTH AND FAMILY WELFARE
Asked by: R.P. MARUTHARAJAA

## GOVERNMENT OF INDIA MINISTRY OF HEALTH AND FAMILY WELFARE DEPARTMENT OF HEALTH AND FAMILY WELFARE

## LOK SABHA UNSTARRED QUESTION NO. 1089 TO BE ANSWERED ON 21 ST JULY, 2017

## KIDNEY FAILURE CASES

## 1089. SHRI R.P. MARUTHARAJAA:

Will the Minister of HEALTH AND FAMILY WELFARE be pleased to state:

(a) whether the Government has taken note of the fact that four to five patients suffer kidney failure due to UTI infection each year which is either caused by the infection itself or heavy dosage of antibiotics ad ministered to treat them;

(b) if so, whether the Government proposes to take any action in this regard; and

- (c) the details of study on antibiotic resistan e?

## ANSWER THE MINISTER OF STATE IN THE MINISTRY OF HEALTH AND FAMILY WELFARE (SMT. ANUP RIYA PATEL )

(a): It  is  a  fact  that  antimicrobial  resistance  is  growing  in  common  bacteria  su Escherichia coli, Klebsiella sp, Enterococcus sp, which can cause urinary tract infection lead to complications like kidney failure. However, there is no p recise data available for UTI leading to Kidney failure.

(b): Government of India has taken serious note of rising antimicrobial resistance (AMR common bacterial pathogens and to address the problem, Ministry of Health & Family Welfa has  launched  th e  'National  Programme  on  Containment  of  Antimicrobial  Resistance'  with National Centre for Disease Control (NCDC) as the coordinating centre.

Under the programme, following activities are being conducted:

- National treatment guidelines for antimicrobial us e in infectious diseases have been released to  serve  as  reference  for  all  hospitals  to  promote  rational  use  of  antimicrobi disseminated for use throughout the country.
- Infection  control  guidelines  are  available  for  use  in  health  care  facilities  t prevent transmission of healthcare associated infections.
- A Network of labs have already been established in this programme for AMR Surveillanc and  surveillance  activity  is  being  carried  out  at  these  sites  and  AMR  trends  are analyzed to understand and monitor the trends of AMR in different geographical regions the country.
- IEC  activities are  undertaken for  creating  awareness  in  community  and  among  medical practitioners for right use of antimicrobial drugs .
- Besides, to check indiscrim inate use of antibiotics, Schedule H1 in the Drugs and Cosmetic Rules  has  covered  24  antibiotics  falling  under  third  and  fourth  generation  beside -anxiety  and  anti - Tuberculosis  drugs  so  as  to  prevent  their  over  the  counter  (OTC)  sa without prescript ion at the pharmacies all over the country. Schedule H1 warning has been printed on the label in a box with red border and the Rx symbol in red. They can be s pharmaceutical chemists only on production of a valid prescription by registered me pr actitioner s.
- Trainings on Antibiotic Stewardship have been initiated by NCDC for different stakeholders to promote rational use of antibiotics.
- A  comprehensive  National  Action  plan  for  containment  of  AMR  has  been  prepared  to address all factors leading t o rise in AMR and has been shared with all stakeholders.

(c): As per trends obtained for the year 2015 from the AMR surveillance being carried ou network  laboratories,  resistance  rates  to  most  of  the  antimicrobials  are  high  in pathogens like E. coli, Klebsiella, Enterococcus, which can cause UTI. The resistance has b observed in fluoroquinolones, third generation cephalosporins, aminoglycosides carbapenems. However, no resistance has been observed in reserve drugs such as vancomyc inS.aureusand colistin in gram negative pathogens.